CN115006446A - Formula for enhancing immunity, preventing and treating influenza and preparation method thereof - Google Patents

Formula for enhancing immunity, preventing and treating influenza and preparation method thereof Download PDF

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CN115006446A
CN115006446A CN202110247497.7A CN202110247497A CN115006446A CN 115006446 A CN115006446 A CN 115006446A CN 202110247497 A CN202110247497 A CN 202110247497A CN 115006446 A CN115006446 A CN 115006446A
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root
portions
radix
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张长禄
丁世仓
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Shengmengtang Hainan Biotechnology Co ltd
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Shengmengtang Hainan Biotechnology Co ltd
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
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Abstract

The invention provides a formula for enhancing immunity, preventing and treating influenza and a preparation method thereof, the raw materials of the formula comprise 15 to 25 portions of radix codonopsitis, 25 to 35 portions of astragalus root, 5 to 15 portions of divaricate saposhnikovia root, 5 to 15 portions of baical skullcap root, 5 to 15 portions of platycodon root, 7 to 17 portions of Chinese thorowax root, 5 to 15 portions of whiteflower hogfennel root, 5 to 15 portions of Szechuan lovage rhizome, 5 to 15 portions of incised notopterygium rhizome and root, 5 to 15 portions of doubleteeth pubescent angelica root, 5 to 15 portions of mint and 5 to 10 portions of liquoric root, the invention adopts the multi-level membrane separation and concentration technology to ensure that the medicinal materials can be fully absorbed in the body, the liquid of the medicinal materials is clear, no precipitate exists, and the cold symptoms of different degrees can be relieved, meanwhile, the immunity of the human body can be improved, and the aims of inhibiting the continuous development of diseases and treating cold can be fulfilled.

Description

Formula for enhancing immunity, preventing and treating influenza and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicinal materials, and particularly relates to a formula for enhancing immunity, preventing and treating influenza and a preparation method thereof.
Background
The cold can be caused by various different viruses and germs, most of cold medicines mainly have the functions of relieving symptoms during cold and cannot help to accelerate self-healing, for example, nasal obstruction, sneezing, rhinorrhea, pharyngalgia and other symptoms caused by the cold, the cold is a self-limiting disease, if the symptoms are slight, the cold medicines are not taken, a small number of cold medicines have antiviral components, antiviral medicines with certain effects on a small number of viruses causing the cold can possibly display limited effects only when being used at an early stage, the aim of medicine treatment is to relieve the symptoms, improve the life quality and prevent and treat complications, so the cold medicines are meaningful for treating the cold, the existing cold medicines have poor drug effects, the cold symptoms are not obviously relieved during use, the immunity of a human body cannot be improved, and the phenomenon of cold recurrence is easy to occur.
Disclosure of Invention
The invention aims to provide a formula for enhancing immunity, preventing and treating influenza and a preparation method thereof, and aims to solve the problems that cold medicines are poor in efficacy, the symptom of the cold is not obviously relieved during use, the immunity of a human body cannot be improved, and the cold is easy to relapse.
The invention provides the following technical scheme, a formula for enhancing immunity, preventing and treating influenza comprises the following raw materials of codonopsis pilosula, astragalus, divaricate saposhnikovia root, baical skullcap root, platycodon root, Chinese thorowax root, whiteflower hogfennel root, szechwan lovage rhizome, incised notopterygium rhizome, doubleteeth pubescent angilica root, mint and liquoric root, and the raw materials of the formula comprise the following traditional Chinese medicines in parts by weight: 15-25 parts of codonopsis pilosula, 25-35 parts of astragalus membranaceus, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of baical skullcap root, 5-15 parts of platycodon grandiflorum, 7-17 parts of radix bupleuri, 5-15 parts of whiteflower hogfennel root, 5-15 parts of szechuan lovage rhizome, 5-15 parts of incised notopterygium rhizome, 5-15 parts of doubleteeth pubescent angelica root, 5-15 parts of mint and 5-10 parts of liquorice.
Preferably, the raw materials are prepared from the following components in parts by weight: 20 parts of codonopsis pilosula, 30 parts of astragalus membranaceus, 10 parts of divaricate saposhnikovia root, 10 parts of baical skullcap root, 10 parts of platycodon root, 12 parts of Chinese thorowax root, 10 parts of whiteflower hogfennel root, 10 parts of szechuan lovage rhizome, 10 parts of incised notopterygium rhizome, 10 parts of doubleteeth pubescent angelica root, 10 parts of mint and 7 parts of liquoric root.
Preferably, the preparation of the cold medicine comprises the following steps: selecting raw materials → pretreating → airing for standby → mixing according to the weight ratio of the Chinese medicinal materials → breaking wall and crushing → heating a medicinal material container → collecting liquid medicine → primary filtering → secondary filtering → multi-stage separation → concentrating the medicinal materials → adding sweetening agent → uniformly stirring → sterilizing and boxing.
Preferably, the Chinese medicinal materials after wall breaking and crushing are 400-500 meshes, the heating of the medicinal material container is carried out in an electric heating mode, and the heating time is 25-30 minutes after boiling by small fire.
Preferably, the sweetener is any one of maltose and mannose, and the sweetener is 2 parts.
Preferably, the preparation method of the cold medicine formula comprises the following steps:
(1) selecting various high-quality medicinal materials, cleaning the medicinal materials, treating different medicinal materials, and air-drying for later use.
(2) 20 parts of codonopsis pilosula, 30 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 10 parts of scutellaria baicalensis, 10 parts of poria cocos, 10 parts of platycodon grandiflorum, 12 parts of radix bupleuri, 10 parts of radix peucedani, 10 parts of ligusticum chuanxiong hort, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of mint and 7 parts of liquorice are mixed and crushed, the crushed medicinal materials are placed in a container, meanwhile, 5 times of clean water of the medicinal materials is added, heating and boiling are carried out, then, the fire is turned for 25 minutes to 30 minutes, and liquid medicine is collected.
(3) The collected liquid medicine is filtered for 2 times to remove impurities in the liquid medicine, the filtration of harmful ingredients such as pesticide residue heavy metal and the like is realized by adopting a multi-stage membrane separation mode, the beneficial ingredients in the liquid medicine can be ensured to control colloid and soluble beneficial macromolecules through physical action, the separated liquid medicine is concentrated, the concentration temperature is 70 degrees, and the concentration time is 1-1.5 hours.
(4) Adding 2 parts of sweetening agent, mixing and stirring the liquid medicine, directly bottling and storing, sterilizing the finished product of the cold medicine, and then externally packaging.
The invention has the beneficial effects that: the invention can prepare various traditional Chinese medicinal materials into medicinal powder and medicinal blocks by a wall-breaking crushing technology, can finish crushing instantly, has high speed, can reserve bioactive components of the medicinal materials to the maximum extent so that the medicinal materials can exert the required medicinal effect, can ensure that the medicinal materials can be fully absorbed in vivo by the cold medicament oral liquid by adopting a multi-stage membrane separation and concentration technology, has clear medicinal liquid without precipitates, can relieve cold symptoms of different degrees, can improve the immunity of a human body, can achieve the aims of inhibiting the continuous development of diseases and treating cold, and can treat cold more thoroughly.
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FIG. 1 is a schematic diagram of the preparation process of the present invention.
Detailed Description
The following detailed description of the preferred embodiments of the present invention is provided to enable those skilled in the art to more readily understand the advantages and features of the present invention and to clearly and clearly define the scope of the present invention.
Example 1
A formulation for enhancing immunity, preventing and treating influenza, characterized in that: the formula raw materials comprise radix codonopsitis, radix astragali, radix sileris, radix scutellariae, poria, platycodon grandiflorum, radix bupleuri, radix peucedani, ligusticum chuanxiong hort, notopterygium root, radix angelicae pubescentis, mint and liquorice, and the formula raw materials comprise the following traditional Chinese medicines in parts by weight: 15-25 parts of codonopsis pilosula, 25-35 parts of astragalus membranaceus, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of baical skullcap root, 5-15 parts of platycodon grandiflorum, 7-17 parts of radix bupleuri, 5-15 parts of whiteflower hogfennel root, 5-15 parts of szechuan lovage rhizome, 5-15 parts of incised notopterygium rhizome, 5-15 parts of doubleteeth pubescent angelica root, 5-15 parts of mint and 5-10 parts of liquorice.
Preferably, the raw materials are prepared from the following components in parts by weight: 20 parts of codonopsis pilosula, 30 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 10 parts of scutellaria baicalensis, 10 parts of poria, 10 parts of platycodon grandiflorum, 12 parts of radix bupleuri, 10 parts of radix peucedani, 10 parts of ligusticum chuanxiong hort, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of mint and 7 parts of liquorice.
Preferably, the preparation of the cold medicine comprises the following steps: selecting raw materials → pretreating → airing for standby → mixing according to the weight ratio of the Chinese medicinal materials → breaking wall and crushing → heating a medicinal material container → collecting liquid medicine → primary filtering → secondary filtering → multi-stage separation → concentrating the medicinal materials → adding sweetening agent → uniformly stirring → sterilizing and boxing.
Preferably, the Chinese medicinal materials after wall breaking and crushing are 400-500 meshes, the heating of the medicinal material container is carried out in an electric heating mode, and the heating time is 25-30 minutes after boiling by small fire.
Preferably, the sweetener is any one of maltose and mannose, and the sweetener is 2 parts.
Preferably, the preparation method of the cold medicine formula comprises the following steps:
(1) selecting various high-quality medicinal materials, cleaning the medicinal materials, treating different medicinal materials, and air-drying for later use.
(2) 20 parts of codonopsis pilosula, 30 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 10 parts of scutellaria baicalensis, 10 parts of poria cocos, 10 parts of platycodon grandiflorum, 12 parts of radix bupleuri, 10 parts of radix peucedani, 10 parts of ligusticum chuanxiong hort, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of mint and 7 parts of liquorice are mixed and crushed, the crushed medicinal materials are placed in a container, meanwhile, 5 times of clean water of the medicinal materials is added, heating and boiling are carried out, then, the fire is turned for 25 minutes to 30 minutes, and liquid medicine is collected.
(3) The collected liquid medicine is filtered for 2 times, impurities in the liquid medicine are removed, the filtration of harmful ingredients such as pesticide residue heavy metal and the like is realized by adopting a multi-stage membrane separation mode, the beneficial ingredients in the liquid medicine can be ensured to control colloid and soluble beneficial macromolecules through physical action, the separated liquid medicine is concentrated, the concentration temperature is 70 degrees, and the concentration time is 1-1.5 hours.
(4) Adding 2 parts of sweetening agent, mixing and stirring the liquid medicine, directly bottling and storing, sterilizing the finished product of the cold medicine, and then externally packaging.
Example 2
A formulation for enhancing immunity, preventing and treating influenza, characterized in that: the formula raw materials comprise radix codonopsitis, radix astragali, radix sileris, radix scutellariae, poria, platycodon grandiflorum, radix bupleuri, radix peucedani, ligusticum chuanxiong hort, notopterygium root, radix angelicae pubescentis, mint and liquorice, and the formula raw materials comprise the following traditional Chinese medicines in parts by weight: 15-25 parts of codonopsis pilosula, 25-35 parts of astragalus membranaceus, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of baical skullcap root, 5-15 parts of platycodon grandiflorum, 7-17 parts of radix bupleuri, 5-15 parts of whiteflower hogfennel root, 5-15 parts of szechuan lovage rhizome, 5-15 parts of incised notopterygium rhizome, 5-15 parts of doubleteeth pubescent angelica root, 5-15 parts of mint and 5-10 parts of liquorice.
Preferably, the raw materials are prepared from the following components in parts by weight: 15 parts of codonopsis pilosula, 25 parts of astragalus mongholicus, 5 parts of divaricate saposhnikovia root, 5 parts of scutellaria baicalensis, 5 parts of poria, 5 parts of platycodon grandiflorum, 7 parts of radix bupleuri, 5 parts of radix peucedani, 5 parts of ligusticum chuanxiong hort, 5 parts of notopterygium root, 5 parts of radix angelicae pubescentis, 5 parts of mint and 5 parts of liquorice.
Preferably, the preparation of the cold medicine comprises the following steps: selecting raw materials → pretreating → airing for later use → mixing according to the weight ratio of the Chinese medicinal materials → wall breaking and crushing → heating of a medicinal material container → collecting medicinal liquid → primary filtering → secondary filtering → multistage separation → concentration of the medicinal materials → adding of a sweetening agent → uniform stirring → sterilization and encasement.
Preferably, the Chinese medicinal materials after wall breaking and crushing are 400-500 meshes, the heating of the medicinal material container is carried out in an electric heating mode, and the heating time is 25-30 minutes after boiling by small fire.
Preferably, the sweetener is any one of maltose and mannose, and the sweetener is 2 parts.
Preferably, the preparation method of the cold medicine formula comprises the following steps:
(1) selecting various high-quality medicinal materials, cleaning the medicinal materials, treating different medicinal materials, and air-drying for later use.
(2) 15 parts of codonopsis pilosula, 25 parts of astragalus mongholicus, 5 parts of divaricate saposhnikovia root, 5 parts of scutellaria baicalensis, 5 parts of poria cocos, 5 parts of platycodon grandiflorum, 7 parts of radix bupleuri, 5 parts of radix peucedani, 5 parts of ligusticum chuanxiong, 5 parts of notopterygium root, 5 parts of radix angelicae pubescentis, 5 parts of mint and 5 parts of liquorice are mixed and crushed, the crushed medicinal materials are placed in a container, meanwhile, 5 times of clear water of the medicinal materials is added, heating and boiling are carried out, then, the fire is turned for 25 minutes to 30 minutes, and liquid medicine is collected.
(3) The collected liquid medicine is filtered for 2 times to remove impurities in the liquid medicine, the filtration of harmful ingredients such as pesticide residue heavy metal and the like is realized by adopting a multi-stage membrane separation mode, the beneficial ingredients in the liquid medicine can be ensured to control colloid and soluble beneficial macromolecules through physical action, the separated liquid medicine is concentrated, the concentration temperature is 70 degrees, and the concentration time is 1-1.5 hours.
(4) Adding 2 parts of sweetening agent, mixing and stirring the liquid medicine, directly bottling and storing, sterilizing the finished product of the cold medicine, and then externally packaging.
Example 3
A formulation for enhancing immunity, preventing and treating influenza, characterized in that: the formula comprises the following raw materials of codonopsis pilosula, astragalus membranaceus, divaricate saposhnikovia root, scutellaria baicalensis, poria, platycodon grandiflorum, radix bupleuri, radix peucedani, ligusticum wallichii, notopterygium root, radix angelicae pubescentis, mint and liquorice, and the formula comprises the following traditional Chinese medicines in parts by weight: 15-25 parts of codonopsis pilosula, 25-35 parts of astragalus membranaceus, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of baical skullcap root, 5-15 parts of platycodon grandiflorum, 7-17 parts of radix bupleuri, 5-15 parts of whiteflower hogfennel root, 5-15 parts of szechuan lovage rhizome, 5-15 parts of incised notopterygium rhizome, 5-15 parts of doubleteeth pubescent angelica root, 5-15 parts of mint and 5-10 parts of liquorice.
Preferably, the raw materials are prepared from the following components in parts by weight: 25 parts of codonopsis pilosula, 35 parts of astragalus membranaceus, 15 parts of divaricate saposhnikovia root, 15 parts of baical skullcap root, 15 parts of platycodon root, 17 parts of Chinese thorowax root, 15 parts of whiteflower hogfennel root, 15 parts of szechuan lovage rhizome, 15 parts of incised notopterygium rhizome, 15 parts of doubleteeth pubescent angilica root, 15 parts of mint and 10 parts of liquoric root.
Preferably, the preparation of the cold medicine comprises the following steps: selecting raw materials → pretreating → airing for standby → mixing according to the weight ratio of the Chinese medicinal materials → breaking wall and crushing → heating a medicinal material container → collecting liquid medicine → primary filtering → secondary filtering → multi-stage separation → concentrating the medicinal materials → adding sweetening agent → uniformly stirring → sterilizing and boxing.
Preferably, the Chinese medicinal materials after wall breaking and crushing are 400-500 meshes, the heating of the medicinal material container is carried out in an electric heating mode, and the heating time is 25-30 minutes after boiling by small fire.
Preferably, the sweetener is any one of maltose and mannose, and the sweetener is 2 parts.
Preferably, the preparation method of the cold medicine formula comprises the following steps:
(1) selecting various high-quality medicinal materials, cleaning the medicinal materials, treating different medicinal materials, and air drying for later use.
(2) Mixing and crushing 25 parts of codonopsis pilosula, 35 parts of astragalus membranaceus, 15 parts of divaricate saposhnikovia root, 15 parts of scutellaria baicalensis, 15 parts of poria cocos, 15 parts of platycodon grandiflorum, 17 parts of radix bupleuri, 15 parts of radix peucedani, 15 parts of ligusticum chuanxiong hort, 15 parts of notopterygium root, 15 parts of radix angelicae pubescentis, 15 parts of mint and 10 parts of liquorice, placing the crushed medicinal materials in a container, adding 5 times of clear water into the container, heating and decocting the mixture until the mixture is boiled, turning to small fire for 25 to 30 minutes, and collecting liquid medicine.
(3) The collected liquid medicine is filtered for 2 times, impurities in the liquid medicine are removed, the filtration of harmful ingredients such as pesticide residue heavy metal and the like is realized by adopting a multi-stage membrane separation mode, the beneficial ingredients in the liquid medicine can be ensured to control colloid and soluble beneficial macromolecules through physical action, the separated liquid medicine is concentrated, the concentration temperature is 70 degrees, and the concentration time is 1-1.5 hours.
(4) Adding 2 parts of sweetening agent, mixing and stirring the liquid medicine, directly bottling and storing, sterilizing the finished product of the cold medicine, and then externally packaging.
Experimental cases:
subject: the cold medications of examples 1-3 above were prepared using the same raw materials and processed using the same equipment during the preparation process, with the processed cold medications randomly divided into 3 groups: control group one, control group two and experimental group.
The test method comprises the following steps:
the first control group was processed with the formula of example 2, the second control group was processed with the formula of example 3, and the experimental group was processed with the formula of example 1.
And (4) judging the standard:
the effect is expressed: the color and taste of the cold medicine, the efficacy of the cold medicine, the time for relieving cold symptoms and the capability of improving the immunity of human bodies.
The results of the comparison of the 3 groups of cold medications are shown in the following table:
Figure BDA0002964612310000071
Figure BDA0002964612310000081
through checking 3 groups of experiments, the cold medicine dry in the experimental group has clear liquid, no precipitate, sweet taste and long drug effect action time, can quickly relieve cold symptoms, can improve the immunity of a human body, and achieves the aim of treating both symptoms and root causes of cold.
The above description is only an embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that are not thought of through the inventive work should be included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope defined by the claims.

Claims (6)

1. A formulation for enhancing immunity in the prevention and treatment of influenza, characterized in that: the formula raw materials comprise radix codonopsitis, radix astragali, radix sileris, radix scutellariae, poria, platycodon grandiflorum, radix bupleuri, radix peucedani, ligusticum chuanxiong hort, notopterygium root, radix angelicae pubescentis, mint and liquorice, and the formula raw materials comprise the following traditional Chinese medicines in parts by weight: 15-25 parts of codonopsis pilosula, 25-35 parts of astragalus membranaceus, 5-15 parts of divaricate saposhnikovia root, 5-15 parts of baical skullcap root, 5-15 parts of platycodon grandiflorum, 7-17 parts of radix bupleuri, 5-15 parts of whiteflower hogfennel root, 5-15 parts of szechuan lovage rhizome, 5-15 parts of incised notopterygium rhizome, 5-15 parts of doubleteeth pubescent angelica root, 5-15 parts of mint and 5-10 parts of liquorice.
2. The formulation of claim 1 for enhancing immune prophylaxis and treatment of influenza, wherein: the raw materials comprise the following components in parts by weight: 20 parts of codonopsis pilosula, 30 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 10 parts of scutellaria baicalensis, 10 parts of poria, 10 parts of platycodon grandiflorum, 12 parts of radix bupleuri, 10 parts of radix peucedani, 10 parts of ligusticum chuanxiong hort, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of mint and 7 parts of liquorice.
3. The method of claim 1 for the preparation of a composition for the immunoprophylaxis and treatment of influenza, wherein the immunoprophylaxis is selected from the group consisting of: the preparation method of the cold medicine comprises the following steps: selecting raw materials → pretreating → airing for later use → mixing according to the weight ratio of the Chinese medicinal materials → wall breaking and crushing → heating of a medicinal material container → collecting medicinal liquid → primary filtering → secondary filtering → multistage separation → concentration of the medicinal materials → adding of a sweetening agent → uniform stirring → sterilization and encasement.
4. The method of claim 3 for the preparation of a composition for enhancing immunity, preventing and treating influenza, wherein the composition comprises: the traditional Chinese medicine raw materials after wall breaking and crushing are 400-500 meshes, the heating of the medicine container is carried out in an electric heating mode, and the heating time is 25-30 minutes after boiling by turning to soft fire.
5. The method of claim 3, wherein the immunoprophylaxis and treatment of influenza are performed by: the sweetener is any one of maltose and mannose, and the sweetener is 2 parts.
6. The method of claim 3, wherein the immunoprophylaxis and treatment of influenza are performed by: the preparation method of the cold medicine formula comprises the following steps:
(1) selecting various high-quality medicinal materials, cleaning the medicinal materials, treating different medicinal materials, and air-drying for later use.
(2) 20 parts of codonopsis pilosula, 30 parts of astragalus mongholicus, 10 parts of divaricate saposhnikovia root, 10 parts of scutellaria baicalensis, 10 parts of poria, 10 parts of platycodon grandiflorum, 12 parts of radix bupleuri, 10 parts of radix peucedani, 10 parts of ligusticum wallichii, 10 parts of notopterygium root, 10 parts of radix angelicae pubescentis, 10 parts of mint and 7 parts of liquorice are mixed and crushed, the crushed medicinal materials are placed in a container, meanwhile, 5 times of clear water is added into the medicinal materials, the mixture is heated, decocted and boiled, then the mixture is turned to small fire for 25 minutes to 30 minutes, and liquid medicine is collected.
(3) The collected liquid medicine is filtered for 2 times to remove impurities in the liquid medicine, the filtration of harmful ingredients such as pesticide residue heavy metal and the like is realized by adopting a multi-stage membrane separation mode, the beneficial ingredients in the liquid medicine can be ensured to control colloid and soluble beneficial macromolecules through physical action, the separated liquid medicine is concentrated, the concentration temperature is 70 degrees, and the concentration time is 1-1.5 hours.
(4) Adding 2 parts of sweetening agent, mixing and stirring the liquid medicine, directly bottling and storing, sterilizing the finished product of the cold medicine, and then externally packaging.
CN202110247497.7A 2021-03-05 2021-03-05 Formula for enhancing immunity, preventing and treating influenza and preparation method thereof Withdrawn CN115006446A (en)

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