CN104435246A - Compound pomegranate bark dampness-excreting diarrhea-checking tablets and preparation method - Google Patents
Compound pomegranate bark dampness-excreting diarrhea-checking tablets and preparation method Download PDFInfo
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- CN104435246A CN104435246A CN201410520027.3A CN201410520027A CN104435246A CN 104435246 A CN104435246 A CN 104435246A CN 201410520027 A CN201410520027 A CN 201410520027A CN 104435246 A CN104435246 A CN 104435246A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 150000001875 compounds Chemical class 0.000 title claims abstract description 12
- 206010012735 Diarrhoea Diseases 0.000 title abstract description 17
- 235000014360 Punica granatum Nutrition 0.000 title abstract 3
- 241000219991 Lythraceae Species 0.000 title 1
- 239000011248 coating agent Substances 0.000 claims abstract description 7
- 238000000576 coating method Methods 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 208000004880 Polyuria Diseases 0.000 claims description 14
- 230000035619 diuresis Effects 0.000 claims description 14
- 230000001142 anti-diarrhea Effects 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000008187 granular material Substances 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 7
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 7
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 5
- 239000012141 concentrate Substances 0.000 claims description 5
- 238000007602 hot air drying Methods 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 5
- 239000002002 slurry Substances 0.000 claims description 5
- 239000007779 soft material Substances 0.000 claims description 5
- 238000005507 spraying Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 13
- 239000003814 drug Substances 0.000 abstract description 11
- 229940079593 drug Drugs 0.000 abstract description 8
- 210000000952 spleen Anatomy 0.000 abstract description 8
- 208000024891 symptom Diseases 0.000 abstract description 5
- 241000721047 Danaus plexippus Species 0.000 abstract description 4
- 206010010774 Constipation Diseases 0.000 abstract description 3
- 206010000087 Abdominal pain upper Diseases 0.000 abstract description 2
- 230000001684 chronic effect Effects 0.000 abstract description 2
- 206010009887 colitis Diseases 0.000 abstract description 2
- 239000002994 raw material Substances 0.000 abstract description 2
- 244000294611 Punica granatum Species 0.000 abstract 2
- 206010000060 Abdominal distension Diseases 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 241000675108 Citrus tangerina Species 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000002598 Inula helenium Nutrition 0.000 abstract 1
- 244000116484 Inula helenium Species 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 241001180876 Saposhnikovia Species 0.000 abstract 1
- 208000027503 bloody stool Diseases 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 208000035861 hematochezia Diseases 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 229910000014 Bismuth subcarbonate Inorganic materials 0.000 description 1
- HWSISDHAHRVNMT-UHFFFAOYSA-N Bismuth subnitrate Chemical compound O[NH+]([O-])O[Bi](O[N+]([O-])=O)O[N+]([O-])=O HWSISDHAHRVNMT-UHFFFAOYSA-N 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- MGLUJXPJRXTKJM-UHFFFAOYSA-L bismuth subcarbonate Chemical compound O=[Bi]OC(=O)O[Bi]=O MGLUJXPJRXTKJM-UHFFFAOYSA-L 0.000 description 1
- 229940036358 bismuth subcarbonate Drugs 0.000 description 1
- 229960001482 bismuth subnitrate Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 241000712461 unidentified influenza virus Species 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses compound pomegranate bark dampness-excreting diarrhea-checking tablets and a preparation method. The preparation method comprises the following steps: by taking pomegranate bark as a monarch drug and eight traditional Chinese medicines such as poria cocos, bighead atractylodes rhizome, elecampane, dried tangerine or orange peel, Divaricate Saposhnikovia Root, white paeony root, liquorice and coptis chinensis as auxiliary raw materials, decocting, tabletting and coating, thereby preparing the diarrhea-checking tablets. The diarrhea-checking tablets have the effects of replenishing qi to invigorate the spleen and excreting dampness and checking diarrhea, are used for treating excessive dampness due to deficiency in spleen and intestine asthenic diarrhea and have obvious curative effects on symptoms such as diarrhea and abdominal distension, constipation, chronic colitis, sloppy diarrhea or mucous bloody stool or constipation, stomachache and the like.
Description
Technical field
The present invention relates to the technical field of Chinese patent medicine, espespecially a kind of Pericarpium Granati compound recipe eliminating dampness by diuresis antidiarrheal tablet and preparation method.
Background technology
Diarrhoea is common a kind of symptom or disease, and diarrhoea is conducive to pungent and the toxicant of removing intestinal, and conventional diarrhea, as bismuth subcarbonate, bismuth subnitrate etc.Bismuth is water insoluble, has astriction, can be attached to gut mucosal surface and shield after for oral administration, but also has certain toxic and side effects and untoward reaction to human body simultaneously; Although the traditional Chinese medical science has many diarrhoea medicines, its curative effect is not fairly obvious, how to improve the curative effect of the traditional Chinese medical science to symptom of diarrhea, has become the focus that vast traditional Chinese medical science worker pays close attention to.
Summary of the invention
A kind of Pericarpium Granati compound recipe eliminating dampness by diuresis antidiarrheal tablet of the present invention and preparation method, employing Pericarpium Granati is monarch drug, be aided with Poria again, the Rhizoma Atractylodis Macrocephalae, the Radix Aucklandiae, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, the Radix Paeoniae Alba, Radix Glycyrrhizae, Rhizoma Coptidis 8 taste Chinese medicine is raw material, processing step through decoction, film-making, coating prepares eliminating dampness by diuresis antidiarrheal tablet, realize replenishing QI to invigorate the spleen, the object of eliminating dampness by diuresis antidiarrheal.
To achieve these goals, technical solution of the present invention is: the Chinese medicinal components of a kind of Pericarpium Granati compound recipe eliminating dampness by diuresis antidiarrheal tablet and preparation method: Pericarpium Granati 20%, Poria 10% ~ 12%, the Rhizoma Atractylodis Macrocephalae 8% ~ 10%, the Radix Aucklandiae 10% ~ 12%, Pericarpium Citri Reticulatae 8% ~ 10%, Radix Saposhnikoviae 10% ~ 12%, the Radix Paeoniae Alba 10% ~ 12%, Radix Glycyrrhizae 8% ~ 10%, Rhizoma Coptidis 8% ~ 10%.
Preparation process is as follows:
(1) decoct: Chinese medicinal components is pulverized, inserts in Decocting pot and add 10 times of pure water, decoct 5h, get decoction liquor; Add family 6 again by doubly pure water, decoct 5h, merge decoction liquor, use 100 mesh screen, then carry out oil-water separation through gun barrel, will isolate decoction liquor concentrates in concentration tank, then carry out spraying dry, and obtain concentrated powder;
(2) film-making: concentrated powder is inserted in kneader and adds ethanol and be uniformly mixed, make soft material; Be squeezed into granule, carrying out hot air drying, dried granule adds Borneolum Syntheticum and is uniformly mixed, and is pressed into the tablet of 50mg by tablet machine;
(3) coating: in rotary blender, the tablet made evenly is sprayed and shine one deck Opadry liquid slurry, wrap a glace to tablet outside, dry, obtain compound recipe eliminating dampness by diuresis antidiarrheal tablet.
Effect of Chinese medicinal components of the present invention and effect: wherein: have antibacterial, resisiting influenza virus effect with Pericarpium Granati can relieving diarrhea with astringents be monarch drug; Regulating qi-flowing for strengthening spleen eliminating dampness by diuresis effect played altogether by Poria, Radix Saposhnikoviae, the Pericarpium Citri Reticulatae Rhizoma Atractylodis Macrocephalae, and the spleen invigorating effect strengthening monarch drug is ministerial drug; Radix Paeoniae Alba relieving spasm to stop pain, easing the affected liver reason spleen, soup only profit after Rhizoma Coptidis, it is adjuvant drug that Radix Aucklandiae circulation of qi promoting is fallen apart stagnant; Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, influences each other, collaborative altogether as making medicine, play replenishing QI to invigorate the spleen altogether, effect of eliminating dampness by diuresis antidiarrheal, for the treatment of insufficiency of the spleen leading to overabundance of dampness, the sliding chronic diarrhea of intestinal,, chronic colitis, diarrhea not well to diarrhoea abdominal distention, defecation or mucus hemafecia or constipation, the symptoms such as stomachache have significant curative effect.
Detailed description of the invention
Embodiment 1
(1) component:
Pericarpium Granati 20%, Poria 10%, the Rhizoma Atractylodis Macrocephalae 10%, the Radix Aucklandiae 10%, Pericarpium Citri Reticulatae 10%, Radix Saposhnikoviae 10%, the Radix Paeoniae Alba 10%, Radix Glycyrrhizae 10%, Rhizoma Coptidis 10%.
(2) preparation process is as follows:
1. decoct: Chinese medicinal components is pulverized, inserts in Decocting pot and add 10 times of pure water, decoct 5h, get decoction liquor; Add 6 again by times pure water, decoct 5h, merge decoction liquor, use 100 mesh screen, then carry out oil-water separation through gun barrel, will isolate decoction liquor concentrates in concentration tank, then carry out spraying dry, and obtain concentrated powder;
2. film-making: concentrated powder is inserted in kneader and adds ethanol and be uniformly mixed, make soft material; Be squeezed into granule, carrying out hot air drying, dried granule adds Borneolum Syntheticum and is uniformly mixed, and is pressed into the tablet of 50mg by tablet machine;
3. coating: in mixer, the tablet made evenly is sprayed and shine one deck Opadry liquid slurry, wrap a glace to tablet outside, dry, obtain compound recipe eliminating dampness by diuresis antidiarrheal tablet.
Embodiment 2
(1) component:
Pericarpium Granati 20%, Poria 11%, the Rhizoma Atractylodis Macrocephalae 9%, the Radix Aucklandiae 11%, Pericarpium Citri Reticulatae 9%, Radix Saposhnikoviae 11%, the Radix Paeoniae Alba 11%, Radix Glycyrrhizae 9, Rhizoma Coptidis 9%.
(2) technique preparation process is as follows:
1. decoct: Chinese medicinal components is pulverized, inserts in Decocting pot and add 10 times of pure water, decoct 5h, get decoction liquor; Add 6 again by times pure water, decoct 5h, merge decoction liquor, use 100 mesh screen, then carry out oil-water separation through gun barrel, will isolate decoction liquor concentrates in concentration tank, then carry out spraying dry, and obtain concentrated powder;
2. film-making: concentrated powder is inserted in kneader and adds ethanol and be uniformly mixed, make soft material; Be squeezed into granule, carrying out hot air drying, dried granule adds Borneolum Syntheticum and is uniformly mixed, and is pressed into the tablet of 50mg by tablet machine;
3. coating: in mixer, the tablet made evenly is sprayed and shine one deck Opadry liquid slurry, wrap a glace to tablet outside, dry, obtain nourishing the stomach blood stasis dispelling XIAOSHI PIAN.
Embodiment 3
(1) component:
Pericarpium Granati 20%, Poria 12%, the Rhizoma Atractylodis Macrocephalae 8%, the Radix Aucklandiae 12%, Pericarpium Citri Reticulatae 8%, Radix Saposhnikoviae 12%, the Radix Paeoniae Alba 12%, Radix Glycyrrhizae 8%, Rhizoma Coptidis 8%.
(2) technique preparation process is as follows:
1. decoct: Chinese medicinal components is pulverized, inserts in Decocting pot and add 10 times of pure water, decoct 5h, get decoction liquor; Add 6 again by times pure water, decoct 5h, merge decoction liquor, use 100 mesh screen, then carry out oil-water separation through gun barrel, will isolate decoction liquor concentrates in concentration tank, then carry out spraying dry, and obtain concentrated powder;
2. film-making: concentrated powder is inserted in kneader and adds ethanol and be uniformly mixed, make soft material; Be squeezed into granule, carrying out hot air drying, dried granule adds Borneolum Syntheticum and is uniformly mixed, and is pressed into the tablet of 50mg by tablet machine;
3. coating: in mixer, the tablet made evenly is sprayed and shine one deck Opadry liquid slurry, wrap a glace to tablet outside, dry, obtain compound recipe eliminating dampness by diuresis antidiarrheal tablet.
Application result:
Apply this product clinical treatment through 150 routine patients, after medication, symptom can well be alleviated, and has no obvious toxic and side effects, do not find untoward reaction in application patient; Total effective rate reaches 100%.
The above; embodiment is only be described the preferred embodiment of the present invention; not scope of the present invention is limited; under the prerequisite of spirit not departing from the technology of the present invention; the various distortion that this area engineers and technicians make technical scheme of the present invention and improvement, all should fall in protection domain that claims of the present invention determine.
Claims (2)
1. Pericarpium Granati compound recipe eliminating dampness by diuresis antidiarrheal tablet and a preparation method, is characterized in that: Chinese medicinal components is Pericarpium Granati 20%, Poria 10% ~ 12%, the Rhizoma Atractylodis Macrocephalae 8% ~ 10%, the Radix Aucklandiae 10% ~ 12%, Pericarpium Citri Reticulatae 8% ~ 10%, Radix Saposhnikoviae 10% ~ 12%, the Radix Paeoniae Alba 10% ~ 12%, Radix Glycyrrhizae 8% ~ 10%, Rhizoma Coptidis 8% ~ 10%.
2. a kind of Pericarpium Granati compound recipe eliminating dampness by diuresis antidiarrheal tablet according to claim 1 and preparation method, is characterized in that: preparation process is as follows:
(1) decoct: Chinese medicinal components is pulverized, inserts in Decocting pot and add 10 times of pure water, decoct 5h, get decoction liquor; Add family 6 again by doubly pure water, decoct 5h, merge decoction liquor, use 100 mesh screen, then carry out oil-water separation through gun barrel, will isolate decoction liquor concentrates in concentration tank, then carry out spraying dry, and obtain concentrated powder;
(2) film-making: concentrated powder is inserted in kneader and adds ethanol and be uniformly mixed, make soft material; Be squeezed into granule, carrying out hot air drying, dried granule adds Borneolum Syntheticum and is uniformly mixed, and is pressed into the tablet of 50mg by tablet machine;
(3) coating: in rotary blender, the tablet made evenly is sprayed and shine one deck Opadry liquid slurry, wrap a glace to tablet outside, dry, obtain compound recipe eliminating dampness by diuresis antidiarrheal tablet.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410520027.3A CN104435246A (en) | 2014-10-08 | 2014-10-08 | Compound pomegranate bark dampness-excreting diarrhea-checking tablets and preparation method |
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| CN201410520027.3A CN104435246A (en) | 2014-10-08 | 2014-10-08 | Compound pomegranate bark dampness-excreting diarrhea-checking tablets and preparation method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250954A (en) * | 2015-10-19 | 2016-01-20 | 马应龙药业集团股份有限公司 | Traditional Chinese medicine for treating irritable bowel syndrome and preparation method of traditional Chinese medicine |
| CN106237245A (en) * | 2016-08-30 | 2016-12-21 | 林天东 | A kind of Chinese medicine composition treating acute and chronic diarrhea and preparation thereof and application |
| CN106236954A (en) * | 2016-08-05 | 2016-12-21 | 太仓张根木生物科技有限公司 | A kind of herbal mixture of antiinflammatory antidiarrheal and preparation method thereof |
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2014
- 2014-10-08 CN CN201410520027.3A patent/CN104435246A/en active Pending
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| CN105250954A (en) * | 2015-10-19 | 2016-01-20 | 马应龙药业集团股份有限公司 | Traditional Chinese medicine for treating irritable bowel syndrome and preparation method of traditional Chinese medicine |
| CN106236954A (en) * | 2016-08-05 | 2016-12-21 | 太仓张根木生物科技有限公司 | A kind of herbal mixture of antiinflammatory antidiarrheal and preparation method thereof |
| CN106237245A (en) * | 2016-08-30 | 2016-12-21 | 林天东 | A kind of Chinese medicine composition treating acute and chronic diarrhea and preparation thereof and application |
| CN106237245B (en) * | 2016-08-30 | 2018-03-27 | 林天东 | A kind of Chinese medicine composition for treating acute and chronic diarrhea and its preparation and application |
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