CN106581345A - Stomach disease treating medicine and production method thereof - Google Patents

Stomach disease treating medicine and production method thereof Download PDF

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Publication number
CN106581345A
CN106581345A CN201510670257.2A CN201510670257A CN106581345A CN 106581345 A CN106581345 A CN 106581345A CN 201510670257 A CN201510670257 A CN 201510670257A CN 106581345 A CN106581345 A CN 106581345A
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CN
China
Prior art keywords
parts
radix
medicine
extractum
gastropathy
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Pending
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CN201510670257.2A
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Chinese (zh)
Inventor
龙凤荣
王瑶
李珂
孙敏
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GUIZHOU HONGKANG PHARMACEUTICAL CO Ltd
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GUIZHOU HONGKANG PHARMACEUTICAL CO Ltd
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Priority to CN201510670257.2A priority Critical patent/CN106581345A/en
Publication of CN106581345A publication Critical patent/CN106581345A/en
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Abstract

The invention discloses a stomach disease treating medicine and a production method thereof, wherein the stomach disease treating medicine is mainly prepared from licorice root, angelica dahurica, codonopsis pilosula, panax notoginseng, milkvetch root, radix aucklandiae, radix cynanchi auriculati, scutellaria barbata d. don, cynanchum otophyllum, saruma henryi oliv, radix cynanchi auriculati, eaglewood, sauussurea costus, radix aristolochiae, magnolia officinalis, longpeduncle kadsura root, radix pseudostellariae, pericarpium citri reticulatae, and pinellia ternata processed with ginger. The stomach disease treating medicine of the present invention has effects of stomach fire clearing, stomach yin nourishing, food stagnancy removing, qi promoting and pain stopping, can be used for stomach diseases, and further has characteristics of significant treatment effect, short treatment cycle, safety, and no side effect.

Description

One kind treats stomach medicine and preparation method thereof
Technical field
The present invention relates to a kind of treat medicine of gastropathy and preparation method thereof, belong to the field of medicine technology.
Technical background
People's work strain, pressure are big now, and rhythm of life is also increasingly faster, change and the not good living habit of dietary structure, And overwork, frightened, Nervous and Mental Factors etc. affect, the patient of gastropathy increases year by year, and sickness rate is high.Gastropathy be a kind of commonly encountered diseases, Frequently-occurring disease, cardinal symptom have gastric abscess, gastric and duodenal ulcers, hyperchlorhydria, cold syndrome of the stomach etc., gastropathy include acute or chronic gastritis, Superficial gastritiss, oesophageal reflux gastritis, peracidity gastritis, gastric ulcer and duodenal ulcer etc. are various, such as control not in time And treatment, can also cause the incurable diseases such as gastric cancer.
For above-mentioned disease, although have much currently used for the medicine for the treatment of gastropathy, but most drug is slow just for drug effect Slowly, treatment cycle is long.
The content of the invention:
It is an object of the present invention to provide a kind of treat medicine of gastropathy and preparation method thereof.The medicine has clearing stomach fire, grows The effect of stomach-Yin, intestinal stasis relieving removing food stagnancy, promoting the circulation of QI to relieve pain.Can be used for gastropathy;Evident in efficacy, treatment cycle is short, has no side effect safely.
To solve above-mentioned technical problem, the present invention employs the following technical solutions realization:A kind of medicine for treating gastropathy, by weight Calculate, mainly by Radix Glycyrrhizae 20-35 parts, Radix Angelicae Dahuricae 25-35 parts, Radix Codonopsis 20-30 parts, Radix Notoginseng 15-25 parts, Radix Astragali 10-15 parts, Radix Aucklandiae 10-20 parts, Radix cynanchi wilfordii 10-20 parts, Herba Scutellariae Barbatae 1-10 parts, Radix Paeoniae Alba 1-10 parts, Herba Asari 20-30 parts, Radix cynanchi wilfordii 25-35 parts, Lignum Aquilariae Resinatum 25-35 parts, Radix Aucklandiae (Radix Vladimiriae) 25-35 parts, Radix Aristolochiae 25-35 parts, Cortex Magnoliae Officinalis 15-25 part, Radix Kadsurae longipedunculatae 10-20 Part, Radix Pseudostellariae 25-35 parts, Pericarpium Citri Reticulatae 25-35 parts and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 25-35 parts are made.
It is aforesaid treatment gastropathy medicine in, calculate by weight, mainly by 28 parts of Radix Glycyrrhizae, 30 parts of the Radix Angelicae Dahuricae, 25 parts of Radix Codonopsis, 20 parts of Radix Notoginseng, 12 parts of the Radix Astragali, 15 parts of the Radix Aucklandiae, 15 parts of Radix cynanchi wilfordii, 5 parts of Herba Scutellariae Barbatae, 5 parts of the Radix Paeoniae Alba, 25 parts of Herba Asari, 30 parts of Radix cynanchi wilfordii, 30 parts of Lignum Aquilariae Resinatum, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Radix Aristolochiae, 20 parts of Cortex Magnoliae Officinalis, 15 parts of Radix Kadsurae longipedunculatae, Radix Pseudostellariae 30 parts of 30 parts, 30 parts of Pericarpium Citri Reticulatae and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are made.
A kind of manufacture method of the medicine of aforesaid treatment gastropathy, takes said medicine, can add adjuvant, it is also possible to be not added with adjuvant, Make oral formulations.
It is aforesaid treatment gastropathy medicine manufacture method in, the oral formulations be granule, capsule, tablet, pill, Powder or cream.
In the manufacture method of the medicine of aforesaid treatment gastropathy, the granule so makes:Take said medicine, plus 10 times of amount water Decoct 3 times, each 1.5h, filter, merge decoction liquor, extractum of the relative density for 1.15-1.20 when being condensed into 50-60 DEG C, The starch of extractum and extractum amount 20% and 20% dextrine powder mixing granulation, are dried, obtain final product.
In the manufacture method of the medicine of aforesaid treatment gastropathy, the manufacture method of the capsule is:Said medicine is taken, with 6 times The alcohol reflux of amount 70% 2 times, 1 hour every time, extracting solution was filtered, and filtrate recycling ethanol is simultaneously condensed into 50-60 DEG C of phase It is the extractum of 1.20-1.25 to density, separately takes the starch of extractum amount 30% and 0.7% magnesium stearate and mix with extractum, use 60% Alcohol granulation, dry, pulverize, fill capsule, obtain final product.
In the manufacture method of the medicine of aforesaid treatment gastropathy, the manufacture method of the tablet is:Take said medicine, plus 10 times of amounts Decocting is boiled 3 times, each 1.5h, is filtered, and merges decoction liquor, leaching of the relative density for 1.15-1.20 when being condensed into 50-60 DEG C Cream, extractum are mixed with the starch of above-mentioned mixed powder and extractum amount 20%, and tabletting, film coating are obtained final product.
Compared with prior art, medicine of the present invention is mainly by Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Radix Codonopsis, Radix Notoginseng, the Radix Astragali, the Radix Aucklandiae, mountain on the other way round Disappear, it is Herba Scutellariae Barbatae, the Radix Paeoniae Alba, Herba Asari, Radix cynanchi wilfordii, Lignum Aquilariae Resinatum, Radix Aucklandiae (Radix Vladimiriae), Radix Aristolochiae, Cortex Magnoliae Officinalis, Radix Kadsurae longipedunculatae, Radix Pseudostellariae, old Skin and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are made.In prescription, each raw material has good synergism, play altogether clearing stomach fire, grow stomach-Yin, intestinal stasis relieving removing food stagnancy, The effect of promoting the circulation of QI to relieve pain.Can be used for gastropathy;Evident in efficacy, treatment cycle is short, has no side effect safely.
Treatment example:
Poplar ××, man, 60 years old, with acute or chronic gastritis, is entered to eat medicine of the present invention by embodiment 1, after 2 months, symptom It is relieved, after 4 months, recovers normal.
Shen ××, man, 45 years old, with oesophageal reflux gastritis, is entered to eat medicine of the present invention by embodiment 1, after 2 months, Symptom is relieved, and recovers normal after 4 months.
Invention is further described with reference to embodiment, but is not intended as the foundation limited to the present invention.
Specific embodiment:
Embodiment 1.
Formula:Radix Glycyrrhizae 28g, Radix Angelicae Dahuricae 30g, Radix Codonopsis 25g, Radix Notoginseng 20g, Radix Astragali 12g, Radix Aucklandiae 15g, Radix cynanchi wilfordii 15g, Herba Scutellariae Barbatae 5g, Radix Paeoniae Alba 5g, Herba Asari 25g, Radix cynanchi wilfordii 30g, Lignum Aquilariae Resinatum 30g, Radix Aucklandiae (Radix Vladimiriae) 30g, Radix Aristolochiae 30g, Cortex Magnoliae Officinalis 20g, Radix Kadsurae longipedunculatae 15g, Radix Pseudostellariae 30g, Pericarpium Citri Reticulatae 30g and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 30g.
Technique:Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and is merged decoction liquor, is condensed into 50-60 DEG C When relative density for 1.15-1.20 extractum, the starch of extractum and extractum amount 20% and 20% dextrine powder mixing granulation be dried, Obtain final product granule.
Specification:0.5g/ grains.
Usage and dosage:2-3 grains, daily 2-3 time every time.
Embodiment 2.
Formula:Radix Glycyrrhizae 20g, Radix Angelicae Dahuricae 25g, Radix Codonopsis 20g, Radix Notoginseng 15g, Radix Astragali 10g, Radix Aucklandiae 10g, Radix cynanchi wilfordii 10g, half Branch lotus 1g, Radix Paeoniae Alba 1g, Herba Asari 20g, Radix cynanchi wilfordii 25g, Lignum Aquilariae Resinatum 25g, Radix Aucklandiae (Radix Vladimiriae) 25g, Radix Aristolochiae 25g, Cortex Magnoliae Officinalis 15g, Radix Kadsurae longipedunculatae 10g, Radix Pseudostellariae 25g, Pericarpium Citri Reticulatae 25g and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 25g.
Technique:Said medicine is taken, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filter When liquid reclaims ethanol and is condensed into 50-60 DEG C, relative density is the extractum of 1.20-1.25, separately takes the starch and 0.7% of extractum amount 30% Magnesium stearate and extractum mix, with 60% alcohol granulation, dry, pulverize, fill capsule, obtain final product capsule.
Specification:0.5g/ grains.
Usage and dosage:2-3 grains, daily 2-3 time every time.
Embodiment 3.
Formula:Radix Glycyrrhizae 35g, Radix Angelicae Dahuricae 35g, Radix Codonopsis 30g, Radix Notoginseng 25g, Radix Astragali 15g, Radix Aucklandiae 20g, Radix cynanchi wilfordii 20g, half Branch lotus 10g, Radix Paeoniae Alba 10g, Herba Asari 30g, Radix cynanchi wilfordii 35g, Lignum Aquilariae Resinatum 35g, Radix Aucklandiae (Radix Vladimiriae) 35g, Radix Aristolochiae 35g, Cortex Magnoliae Officinalis 25g, Radix Kadsurae longipedunculatae 20g, Radix Pseudostellariae 35g, Pericarpium Citri Reticulatae 35g and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 35g.
Technique:Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and is merged decoction liquor, is condensed into 50-60 DEG C When relative density for 1.15-1.20 extractum, the starch of extractum and extractum amount 20% and 20% dextrine powder mixing granulation be dried, Obtain final product granule.
Specification:0.5g/ grains.
Usage and dosage:2-3 grains, daily 2-3 time every time.

Claims (7)

1. a kind of medicine for treating gastropathy, it is characterised in that:Calculate by weight, mainly by Radix Glycyrrhizae 20-35 parts, Radix Angelicae Dahuricae 25-35 parts, Radix Codonopsis 20-30 parts, Radix Notoginseng 15-25 parts, Radix Astragali 10-15 parts, Radix Aucklandiae 10-20 parts, Radix cynanchi wilfordii 10-20 parts, Herba Scutellariae Barbatae 1-10 Part, Radix Paeoniae Alba 1-10 parts, Herba Asari 20-30 parts, Radix cynanchi wilfordii 25-35 parts, Lignum Aquilariae Resinatum 25-35 parts, Radix Aucklandiae (Radix Vladimiriae) 25-35 parts, green grass or young crops Radix Aucklandiae 25-35 parts, Cortex Magnoliae Officinalis 15-25 part, Radix Kadsurae longipedunculatae 10-20 parts, Radix Pseudostellariae 25-35 parts, Pericarpium Citri Reticulatae 25-35 parts and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 25-35 parts are made.
2. the medicine of gastropathy is treated as claimed in claim 1, it is characterised in that:Calculate by weight, mainly by 28 parts of Radix Glycyrrhizae, white It is 30 parts of the root of Dahurian angelica, 25 parts of Radix Codonopsis, 20 parts of Radix Notoginseng, 12 parts of the Radix Astragali, 15 parts of the Radix Aucklandiae, 15 parts of Radix cynanchi wilfordii, 5 parts of Herba Scutellariae Barbatae, white 5 parts of Chinese herbaceous peony, 25 parts of Herba Asari, 30 parts of Radix cynanchi wilfordii, 30 parts of Lignum Aquilariae Resinatum, 30 parts of Radix Aucklandiae (Radix Vladimiriae), 30 parts of Radix Aristolochiae, 20 parts of Cortex Magnoliae Officinalis, 30 parts of 15 parts of Radix Kadsurae longipedunculatae, 30 parts of Radix Pseudostellariae, 30 parts of Pericarpium Citri Reticulatae and Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) are made.
3. it is a kind of it is as claimed in claim 1 or 2 treatment gastropathy medicine manufacture method, it is characterised in that:Said medicine is taken, can To add adjuvant, it is also possible to be not added with adjuvant, make oral formulations.
4. the manufacture method for treating the medicine of gastropathy as claimed in claim 3, it is characterised in that:The oral formulations be granule, Capsule, tablet, pill, powder or cream.
5. the manufacture method for treating the medicine of gastropathy as claimed in claim 4, it is characterised in that:The granule so makes:Take Said medicine, plus 10 times amount decoctings boil 3 times, each 1.5h, filter, merge decoction liquor, be condensed into relatively close when 50-60 DEG C The starch of the extractum for 1.15-1.20, extractum and extractum amount 20% and 20% dextrine powder mixing granulation are spent, is dried, is obtained final product.
6. the manufacture method for treating the medicine of gastropathy as claimed in claim 4, it is characterised in that:The manufacture method of the capsule is: Said medicine is taken, with the alcohol reflux 2 times of 6 times of amounts 70%, 1 hour every time, extracting solution was filtered, filtrate recycling ethanol And when being condensed into 50-60 DEG C, relative density is the extractum of 1.20-1.25, separately takes the starch of extractum amount 30% and 0.7% stearic acid Magnesium is mixed with extractum, with 60% alcohol granulation, dry, pulverize, and is filled capsule, is obtained final product.
7. the manufacture method for treating the medicine of gastropathy as claimed in claim 4, it is characterised in that:The manufacture method of the tablet is: Said medicine is taken, plus 10 times of amount decoctings are boiled 3 times, each 1.5h is filtered, and is merged decoction liquor, is condensed into relative when 50-60 DEG C Extractum of the density for 1.15-1.20, extractum are mixed with the starch of above-mentioned mixed powder and extractum amount 20%, tabletting, film coating, Obtain final product.
CN201510670257.2A 2015-10-16 2015-10-16 Stomach disease treating medicine and production method thereof Pending CN106581345A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107551170A (en) * 2017-10-19 2018-01-09 广西民族大学 A kind of Chinese medicine composition for treating gastrointestinal disease and preparation method thereof
CN110302274A (en) * 2019-07-30 2019-10-08 数源汇通(北京)医药科技有限公司 Alleviate the Traditional Chinese drug mixture and preparation method thereof of stomach disease

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107551170A (en) * 2017-10-19 2018-01-09 广西民族大学 A kind of Chinese medicine composition for treating gastrointestinal disease and preparation method thereof
CN110302274A (en) * 2019-07-30 2019-10-08 数源汇通(北京)医药科技有限公司 Alleviate the Traditional Chinese drug mixture and preparation method thereof of stomach disease

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Application publication date: 20170426

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