CN1150041A - Chinese patent medicine for curing gallstones and kidney stones - Google Patents
Chinese patent medicine for curing gallstones and kidney stones Download PDFInfo
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- CN1150041A CN1150041A CN96109863A CN96109863A CN1150041A CN 1150041 A CN1150041 A CN 1150041A CN 96109863 A CN96109863 A CN 96109863A CN 96109863 A CN96109863 A CN 96109863A CN 1150041 A CN1150041 A CN 1150041A
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Abstract
A Chinese patent medicine for treating cholangiocalculus, cholecystolithiasis, choledocholithiasis, cholecystitis and renal calculus is prepared from 14 Chinese medicinal materials such as lysimachia, bitter orange, aucklandia root, rhubarb, Chinese gentian, etc. It has functions of soothing liver and regulating qi, dissolving and draining off calculus, normalizing liver and deinflammation, relieving heat and removing moisture, etc.
Description
The present invention relates to a kind of Chinese patent medicine for the treatment of gallstones and kidney stones, the Chinese medicine that is prepared from for the main pharmacodynamics composition with the Chinese herbal medicine particularly, can be used for treating diseases such as hepatic calculus, cholelithiasis, choledocholithiasis, cholecystitis, urinary system calculus, belong to field of traditional Chinese.
Clinically, calculus is that liver and bile stone and urinary system calculus are seen more with digestion.For the Iithiasic treatment of this class, traditional Therapeutic Method is a surgical calculus removing, and the patient is difficult for accepting because of painful, financial burden weigh; And the postoperative recurrence rate is higher, even some patient operation for the second time of being compelled to do.The another kind of method that adopts is large-scale lithotripsy in treatment at present, and expense is higher, and not necessarily can both be broken, can not arrange the broken back of part calculus, even cause that tube chamber stops up, and causes whole body xanthochromia or hydronephrosis, influence the function of liver, gallbladder or kidney, give to continue to treat and bring difficulty.The common chemical medicine has chenodeoxycholic acid and male deoxycholic acid etc., according to external, the complete lithodialysis rate of moth deoxycholic acid is 13.6%, effectively the lithodialysis rate is 40.5%, the lithodialysis rate of ursodesoxycholic acid is 25.8%, the effective lithodialysis rate of domestic report is 39.5%, and its side effect is more, and the patient who is not suitable for the women of child-bearing age and hepatic and kidney function obstacle takes.In addition, ursodesoxycholic acid can make the calculus calcification, is unfavorable for lithodialysis.Practical application proves: chenodeoxycholic acid and ursodesoxycholic acid medication cycle are long, and lithodialysis blood fat reducing lithagogue effect is poor.At present, also carried out some researchs aspect traditional Chinese medicine lithagogue, and there have the urinary calculus removing Chinese patent medicine to be applied to be clinical, still, if these drug mains based on calculus, carry out lithagogue treatment for the cholelithiasis of major diameter calculus, its effect is undesirable, even does not have effect.
The object of the invention provides a kind of pharmaceutical composition made from Chinese herbal medicine with calculus, fossilization.
The composition of pharmaceutical composition of the present invention is counted by weight ratio:
Herba Lysimachiae 40-70 part
Fructus Aurantii 10-30 part
Radix Aucklandiae 10-30 part
Radix Et Rhizoma Rhei 20-40 part
Radix Gentianae 10-30 part
Endothelium Corneum Gigeriae Galli 20-40 part
Rhizoma Polygoni Cuspidati 40-60 part
The preferred weight proportioning of pig's bile 5-25 part root of herbaceous peony 15-35 part radix bupleuri 20-40 part oriental wormwood 15-35 part root tuber of aromatic turmeric 15-35 part Fructus meliae toosendan 20-40 part root of large-flowered skullcap 10-30 part pharmaceutical composition of the present invention is: the optimum weight proportioning of desmodium 50-65 part Fructus Aurantii 15-25 part banksia rose 15-25 part rheum officinale 25-35 part felwort 15-25 part the membrane of a chicken's gizzard 25-30 part giant knotweed 45-55 part pig's bile 10-20 part root of herbaceous peony 20-30 part radix bupleuri 25-35 part oriental wormwood 20-30 part root tuber of aromatic turmeric 20-30 part Fructus meliae toosendan 25-35 part root of large-flowered skullcap 15-25 part medicine of the present invention is: 30 parts of 25 parts of radix bupleuri of 15 portions of root of herbaceous peonys of 50 parts of pig's biles of 30 parts of giant knotweeds of 20 parts of thes membrane of a chicken's gizzard of 30 portions of felworts of 20 parts of rheum officinales of 20 parts of banksia rose of 60 parts of Fructus Aurantiis of desmodium
25 parts of Herba Artemisiae Scopariaes
25 parts of Radix Curcumaes
30 parts of Fructus Toosendans
20 parts of Radix Scutellariaes
Pharmaceutical composition of the present invention can be prepared into common drug dosage form clinically, for example, and pill, tablet, unguentum, capsule, impact, oral liquid etc.
The pill preparation method of medicine of the present invention is:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 600 grams, make honeyed pill at last with the medicine mixing.
Medicine of the present invention has the good curing effect to gallstones and kidney stones, has multiple functions such as depressed liver-energy dispersing and QI regulating, dissovling and discharging calculus, cholagogue and eliminating inflammation, clearing away heat and eliminating dampness, calculus softening and dissolving.Medicine of the present invention is particularly suitable for being used with the another kind of external used medicine of inventor's development, by oral pills, allomeric function is strengthened, and strengthens the gallbladder wriggling, promotes bile secretion to drain, and further promotes calculus; By the cooperation of inside and outside medicine, can make lax, the expansion of stone location tube chamber height, be retracted again then.The repeated multiple times wriggling can make the calculus that becomes shortcake layer by layer come off like this, and the broken end that comes off can be got rid of external immediately.
Following clinical observation material can prove absolutely the good result of medicine of the present invention.
Clinical observation report
1, physical data:
50 routine patients, male's 24 examples, women's 26 examples; The oldest person 70 years old, reckling 20 years old, surplus the elder of the course of disease reaches 20 year, the shortest person 1 month.
1) the calculus size and the form of observing under the B ultrasonic:
Microlith (diameter is person below 0.5 centimetre) 9 examples, medium calculus (calculus diameter more than or equal to 0.5 centimetre, and be less than or equal to 1.5 centimetres of persons) 25 examples, maximum size (diameter is greater than 1.5 centimetres of persons) 8 examples, muddy stone 3 examples, multiple calculus 5 examples that are full of.
2) calculus size and the form that feces is drawn out washed to draw in the treatment back:
Maximum 0.7 centimetre, minimum as silt sample and grain of rice shape; The calculus as hard as flint that has hits and not broken; The calculus short texture that has is the agglomerate sample.Form has circle, oval, not shaping, has the sense of wax sample individually.
3) complication:
Concurrent cholecystitis person 20 examples, atrophy of gallbladder 2 examples, obstructive jaundice 1 example.
4) various calculus types:
Calculus of intrahepatic duct 3 examples, cholelithiasis 32 examples, choledocholithiasis 5 examples, urinary system calculus 10 examples.
5) tcm syndrome differentiation and typing:
Divide type of depression of QI and damp-heat type two big classes.
2, Therapeutic Method:
The fossil lithagogue pill is for oral administration, is mainly used in the damp-heat type calculi therapy; The fossil lithagogue pill cooperates fossil cream to be used for the treatment of type of depression of QI calculus.
3, criterion of therapeutical effect:
1) recovery from illness:
Through treatment, draw out calculus in the stool, the symptom and sign complete obiteration; The B ultrasonic check confirms the calculus emptying, and common bile duct is clear, no abnormal sound shadow.
2) produce effects:
Symptom and sign obviously alleviates or disappears, and confirms to discharge 1/2 above calculus person through the B ultrasonic check.
3) effective:
Symptom and sign takes a turn for the better or basic the disappearance, confirms that through the B ultrasonic check calculus quantity reduces or obviously dwindles.
4) invalid:
Through 1 course of therapy (30 days), symptom and sign does not have obvious improvement, and B ultrasonic check calculus as before.
4, result:
Among the 50 routine patients, 28 examples of fully recovering, produce effects 10 examples, effective 8 examples, invalid 4 examples, total effective rate is 80%.
Embodiment 1
Prescription:
Herba Lysimachiae 40 grams
Fructus Aurantii 10 grams
The Radix Aucklandiae 10 grams
Radix Et Rhizoma Rhei 20 grams
Radix Gentianae 10 grams
Endothelium Corneum Gigeriae Galli 20 grams
Rhizoma Polygoni Cuspidati 40 grams
Fel Sus domestica 5 grams
The Radix Paeoniae Alba 15 grams
Radix Bupleuri 20 grams
Herba Artemisiae Scopariae 15 grams
Radix Curcumae 15 grams
Fructus Toosendan 20 grams
Radix Scutellariae 10 grams
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 400 grams, make honeyed pill at last with the medicine mixing.
Embodiment 2
Herba Lysimachiae 70 grams
Fructus Aurantii 30 grams
The Radix Aucklandiae 30 grams
Radix Et Rhizoma Rhei 40 grams
Radix Gentianae 30 grams
Endothelium Corneum Gigeriae Galli 40 grams
Rhizoma Polygoni Cuspidati 60 grams
Fel Sus domestica 25 grams
The Radix Paeoniae Alba 35 grams
Radix Bupleuri 40 grams
Herba Artemisiae Scopariae 35 grams
Radix Curcumae 35 grams
Fructus Toosendan 40 grams
Radix Scutellariae 30 grams
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 700 grams, make honeyed pill at last with the medicine mixing.
Embodiment 3
Prescription:
Herba Lysimachiae 50 grams
Fructus Aurantii 15 grams
The Radix Aucklandiae 15 grams
Radix Et Rhizoma Rhei 25 grams
Radix Gentianae 15 grams
Endothelium Corneum Gigeriae Galli 25 grams
Rhizoma Polygoni Cuspidati 45 grams
Fel Sus domestica 10 grams
The Radix Paeoniae Alba 20 grams
Radix Bupleuri 25 grams
Herba Artemisiae Scopariae 20 grams
Radix Curcumae 20 grams
Fructus Toosendan 25 grams
Radix Scutellariae 15 grams
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with alcohol granulation, add magnesium stearate, granulate is used the tablet machine tabletting, makes tablet.
Embodiment 4
Herba Lysimachiae 65 grams
Fructus Aurantii 25 grams
The Radix Aucklandiae 25 grams
Radix Et Rhizoma Rhei 35 grams
Radix Gentianae 25 grams
Endothelium Corneum Gigeriae Galli 30 grams
Rhizoma Polygoni Cuspidati 55 grams
Fel Sus domestica 20 grams
The Radix Paeoniae Alba 30 grams
Radix Bupleuri 35 grams
Herba Artemisiae Scopariae 30 grams
Radix Curcumae 30 grams
Fructus Toosendan 35 grams
Radix Scutellariae 25 grams
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, oven dry is ground into fine powder, after again other several drugs component being mixed, be ground into fine powder together,, cross 100 mesh sieves with above-mentioned Fel Sus domestica cream fine powder mix homogeneously, encapsulated, make capsule.
Embodiment 5
Prescription:
Herba Lysimachiae 60 grams
Fructus Aurantii 20 grams
The Radix Aucklandiae 20 grams
Radix Et Rhizoma Rhei 30 grams
Radix Gentianae 20 grams
Endothelium Corneum Gigeriae Galli 30 grams
Rhizoma Polygoni Cuspidati 50 grams
Fel Sus domestica 15 grams
The Radix Paeoniae Alba 25 grams
Radix Bupleuri 30 grams
Herba Artemisiae Scopariae 25 grams
Radix Curcumae 25 grams
Fructus Toosendan 30 grams
Radix Scutellariae 20 grams
Method for making:
Earlier Herba Lysimachiae, Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati three flavor medicines are decocted with water twice, merge decocting liquid, high temperature is condensed into extractum, then, and with the mixed Fel Sus domestica cream that gets of Fel Sus domestica, after again other several drugs component being mixed, be ground into fine powder together, cross 100 mesh sieves, then this powder and Fel Sus domestica cream mixing, with refining good Mel 700 grams, make honeyed pill at last with the medicine mixing.
Claims (5)
1, a kind of pharmaceutical composition for the treatment of gallstones and kidney stones is characterized in that being made up of the component of following weight ratio:
Herba Lysimachiae 40-70 part
Fructus Aurantii 10-30 part
Radix Aucklandiae 10-30 part
Radix Et Rhizoma Rhei 20-40 part
Radix Gentianae 10-30 part
Endothelium Corneum Gigeriae Galli 20-40 part
Rhizoma Polygoni Cuspidati 40-60 part
Fel Sus domestica 5-25 part
Radix Paeoniae Alba 15-35 part
Radix Bupleuri 20-40 part
Herba Artemisiae Scopariae 15-35 part
Radix Curcumae 15-35 part
Fructus Toosendan 20-40 part
Radix Scutellariae 10-30 part
2,, it is characterized in that forming by the component of following weight ratio according to the pharmaceutical composition of claim 1:
Herba Lysimachiae 50-65 part
Fructus Aurantii 15-25 part
Radix Aucklandiae 15-25 part
Radix Et Rhizoma Rhei 25-35 part
Radix Gentianae 15-25 part
Endothelium Corneum Gigeriae Galli 25-30 part
Rhizoma Polygoni Cuspidati 45-55 part
Fel Sus domestica 10-20 part
Radix Paeoniae Alba 20-30 part
Radix Bupleuri 25-35 part
Herba Artemisiae Scopariae 20-30 part
Radix Curcumae 20-30 part
Fructus Toosendan 25-35 part
Radix Scutellariae 15-25 part
3,, it is characterized in that forming by the component of following weight ratio according to the pharmaceutical composition of claim 2:
60 parts of Herba Lysimachiaes
20 parts of Fructus Aurantiis
20 parts of the Radix Aucklandiae
30 parts of Radix Et Rhizoma Rhei
20 parts of Radix Gentianaes
30 parts of Endothelium Corneum Gigeriae Galli
50 parts of Rhizoma Polygoni Cuspidati
15 parts of Fel Sus domestica
25 parts of the Radix Paeoniae Albas
30 parts of Radix Bupleuri
25 parts of Herba Artemisiae Scopariaes
25 parts of Radix Curcumaes
30 parts of Fructus Toosendans
20 parts of Radix Scutellariaes
4,, it is characterized in that it is any dosage form of acceptable drug clinically according to the pharmaceutical composition of claim 1 or 2 or 3.
5,, it is characterized in that it is a kind of pill according to the pharmaceutical composition of claim 4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109863A CN1052163C (en) | 1996-09-24 | 1996-09-24 | Chinese patent medicine for curing gallstones and kidney stones |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96109863A CN1052163C (en) | 1996-09-24 | 1996-09-24 | Chinese patent medicine for curing gallstones and kidney stones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1150041A true CN1150041A (en) | 1997-05-21 |
| CN1052163C CN1052163C (en) | 2000-05-10 |
Family
ID=5120672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96109863A Expired - Fee Related CN1052163C (en) | 1996-09-24 | 1996-09-24 | Chinese patent medicine for curing gallstones and kidney stones |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1052163C (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101224292B (en) * | 2008-02-20 | 2010-08-04 | 肖永雪 | Medicine for treating cholecystitis and preparing method thereof |
| CN101491652B (en) * | 2009-02-24 | 2012-05-09 | 王成果 | Traditional Chinese medicine lithagogue pill and preparation method thereof |
| CN102579973A (en) * | 2012-02-02 | 2012-07-18 | 陈中元 | Medicine for treating gall-stone |
| CN103230566A (en) * | 2013-04-19 | 2013-08-07 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
| CN104825943A (en) * | 2015-04-22 | 2015-08-12 | 李丽丽 | Cholagogue calculus-expelling traditional Chinese medicine composition for treating cholelithiasis and preparation method thereof |
| CN105031521A (en) * | 2015-06-30 | 2015-11-11 | 赵德欣 | Traditional Chinese medicine composition for treating acute bile duct infection and preparation method thereof |
| CN105597009A (en) * | 2016-01-29 | 2016-05-25 | 粟春生 | Pharmaceutical composition for treating gallstones and preparation method of pharmaceutical composition |
| CN106266130A (en) * | 2016-08-23 | 2017-01-04 | 刘军 | Fast-acting antiphlogistic, ethoxybenzamide Chinese patent medicine preparation |
| CN107737303A (en) * | 2017-11-17 | 2018-02-27 | 闫柏林 | Stone oral liquid is arranged in stagnation resolvation |
| CN107823445A (en) * | 2017-10-10 | 2018-03-23 | 季艮 | A kind of Chinese medicine composition for treating gall stone |
| CN110694032A (en) * | 2019-11-01 | 2020-01-17 | 陕西理工大学 | A Chinese medicinal composition for treating cholelithiasis, nephrolithiasis, and vesical calculus, and its preparation method |
| CN112022999A (en) * | 2020-09-25 | 2020-12-04 | 郭建大 | Traditional Chinese medicine composition for treating liver and gall stone, and preparation method and application thereof |
-
1996
- 1996-09-24 CN CN96109863A patent/CN1052163C/en not_active Expired - Fee Related
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101224292B (en) * | 2008-02-20 | 2010-08-04 | 肖永雪 | Medicine for treating cholecystitis and preparing method thereof |
| CN101491652B (en) * | 2009-02-24 | 2012-05-09 | 王成果 | Traditional Chinese medicine lithagogue pill and preparation method thereof |
| CN102579973A (en) * | 2012-02-02 | 2012-07-18 | 陈中元 | Medicine for treating gall-stone |
| CN103230566A (en) * | 2013-04-19 | 2013-08-07 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
| CN104825943A (en) * | 2015-04-22 | 2015-08-12 | 李丽丽 | Cholagogue calculus-expelling traditional Chinese medicine composition for treating cholelithiasis and preparation method thereof |
| CN105031521A (en) * | 2015-06-30 | 2015-11-11 | 赵德欣 | Traditional Chinese medicine composition for treating acute bile duct infection and preparation method thereof |
| CN105597009A (en) * | 2016-01-29 | 2016-05-25 | 粟春生 | Pharmaceutical composition for treating gallstones and preparation method of pharmaceutical composition |
| CN106266130A (en) * | 2016-08-23 | 2017-01-04 | 刘军 | Fast-acting antiphlogistic, ethoxybenzamide Chinese patent medicine preparation |
| CN107823445A (en) * | 2017-10-10 | 2018-03-23 | 季艮 | A kind of Chinese medicine composition for treating gall stone |
| CN107737303A (en) * | 2017-11-17 | 2018-02-27 | 闫柏林 | Stone oral liquid is arranged in stagnation resolvation |
| CN110694032A (en) * | 2019-11-01 | 2020-01-17 | 陕西理工大学 | A Chinese medicinal composition for treating cholelithiasis, nephrolithiasis, and vesical calculus, and its preparation method |
| CN112022999A (en) * | 2020-09-25 | 2020-12-04 | 郭建大 | Traditional Chinese medicine composition for treating liver and gall stone, and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1052163C (en) | 2000-05-10 |
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