CN103230566A - Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof - Google Patents
Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof Download PDFInfo
- Publication number
- CN103230566A CN103230566A CN2013101366716A CN201310136671A CN103230566A CN 103230566 A CN103230566 A CN 103230566A CN 2013101366716 A CN2013101366716 A CN 2013101366716A CN 201310136671 A CN201310136671 A CN 201310136671A CN 103230566 A CN103230566 A CN 103230566A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- radix
- herba
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
The invention relate to a traditional Chinese medical composition for treating cholecystitis cholelithiasis. The composition is prepared by the following raw material medicines as follows: oriental wormwood, Lysimachia christinae Hance, Polygonum cuspidatum, radix curcumae, elecampane and raw fructus aurantii. The invention further relates to a traditional Chinese medical composition for treating cholecystitis cholelithiasis. The composition is prepared by the following raw material medicines as follows: oriental wormwood, Lysimachia christinae Hance, Polygonum cuspidatum, radix curcumae, elecampane, raw fructus aurantii, Corymbose Hedyotis Herb, rheum officinale and corn stigma. The invention further provides an application of the traditional Chinese medical composition. The traditional Chinese medical composition provided by the invention has the advantages that the traditional Chinese medical composition provided by the invention meets the principle of monarch, minister, assistant and guide in all formula, is exact in curative effect for treating cholecystitis cholelithiasis, and can improve symptoms and alleviate pain of patients. The traditional Chinese medical composition is convenient to use and worth applying.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically, is a kind of Chinese medicine composition and application thereof for the treatment of cholecystitis and cholelithiasis.
Background technology
Cholecystitis and cholelithiasis is a kind of common clinical, frequently-occurring disease, has course of disease characteristics long, that show effect repeatedly, and modern medicine thinks that cholecystitis is many owing to antibacterial and viral infection, and obstruction of bile duct or pancreatic juice cause to multiple chemical factors such as the anti-streams of biliary tract.Along with people's living standard improves day by day, the increase of the change of dietary structure and work life stress, the sickness rate of primary disease is in rising trend.Cholecystitis and cholelithiasis has become one of principal disease that influences human health.
Chinese patent literature CN101045116A discloses a kind of Chinese medicine medicine for the treatment of cholecystitis, made by following bulk drugs: 2～4 parts of Herba Artemisiae Scopariaes, 1～2 part of Radix Scutellariae, 0.6～1.3 part of son, 0.6～1.3 part of Radix Et Rhizoma Rhei, 0.6～1.3 part of the Radix Aucklandiae are practiced in the river, 0.6～1.3 part of Rhizoma Alismatis, 0.6～1.3 part of Radix Bupleuri proves the obviously generation of inflammation-inhibiting of this medicine by the modern pharmacology experimental technique, and the cholecystitis and cholelithiasis model is had prevention and therapeutical effect.
Summary of the invention
The objective of the invention is at deficiency of the prior art, a kind of Chinese medicine composition for the treatment of cholecystitis and cholelithiasis is provided.
One purpose more of the present invention is that the Chinese medicine composition of another kind for the treatment of cholecystitis and cholelithiasis is provided.
Another purpose of the present invention is that a kind of application for the treatment of the Chinese medicine composition of cholecystitis and cholelithiasis is provided.
For achieving the above object, the technical scheme that the present invention takes is: a kind of Chinese medicine composition for the treatment of cholecystitis and cholelithiasis, described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part.
Described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2.5-3.5 part, Herba Lysimachiae 2.5-3.5 part, Rhizoma Polygoni Cuspidati 1.7-1.9 part, Radix Curcumae 1.1-1.3 part, Radix Aucklandiae 1.1-1.3 part, living Fructus Aurantii 1.1-1.3 part.
Described Chinese medicine composition is made by following bulk drugs: 3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis.
For realizing above-mentioned second purpose, the technical scheme that the present invention takes is: a kind of Chinese medicine composition for the treatment of cholecystitis and cholelithiasis, described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part, Herba Hedyotidis Corymbosae 2-4 part, Radix Et Rhizoma Rhei 0.1-0.5 part, Stigma Maydis 2-4 part.
Described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2.5-3.5 part, Herba Lysimachiae 2.5-3.5 part, Rhizoma Polygoni Cuspidati 1.7-1.9 part, Radix Curcumae 1.1-1.3 part, Radix Aucklandiae 1.1-1.3 part, living Fructus Aurantii 1.1-1.3 part, Herba Hedyotidis Corymbosae 2.5-3.5 part, Radix Et Rhizoma Rhei 0.2-0.4 part, Stigma Maydis 2.5-3.5 part.
Described Chinese medicine composition is made by following bulk drugs: 3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis, 3 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 3 parts of Stigma Maydis.
For realizing above-mentioned the 3rd purpose, the technical scheme that the present invention takes is: the application of described Chinese medicine composition in the medicine of preparation treatment cholecystitis and cholelithiasis.
The invention has the advantages that:
The full side's compatibility of Chinese medicine composition of the present invention meets Chinese medicine " monarch " principle, and treatment cholecystitis and cholelithiasis determined curative effect can improve symptom, alleviates the patient suffering.Medication is convenient, is worthy to be popularized.
The specific embodiment
Below in conjunction with embodiment the specific embodiment provided by the invention is elaborated.
The invention provides a kind of Chinese medicine composition one for the treatment of cholecystitis and cholelithiasis, made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part.
Embodiment 1 Chinese medicine composition one
2 parts of Herba Artemisiae Scopariaes, 4 parts of Herba Lysimachiaes, 1.5 parts of Rhizoma Polygoni Cuspidati, 1.5 parts of Radix Curcumaes, 1 part of the Radix Aucklandiae, 1.5 parts of living Fructus Aurantiis.
Embodiment 2 Chinese medicine compositions one
2.2 parts of Herba Artemisiae Scopariaes, 3.7 parts of Herba Lysimachiaes, 1.6 parts of Rhizoma Polygoni Cuspidati, 1.4 parts of Radix Curcumaes, 1.1 parts of the Radix Aucklandiae, 1.4 parts of living Fructus Aurantiis.
Embodiment 3 Chinese medicine compositions one
2.4 parts of Herba Artemisiae Scopariaes, 3.5 parts of Herba Lysimachiaes, 1.7 parts of Rhizoma Polygoni Cuspidati, 1.3 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.3 parts of living Fructus Aurantiis.
Embodiment 4 Chinese medicine compositions one
2.5 parts of Herba Artemisiae Scopariaes, 3.4 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.3 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis.
Embodiment 5 Chinese medicine compositions one
2.6 parts of Herba Artemisiae Scopariaes, 3.2 parts of Herba Lysimachiaes, 1.9 parts of Rhizoma Polygoni Cuspidati, 1.1 parts of Radix Curcumaes, 1.4 parts of the Radix Aucklandiae, 1.1 parts of living Fructus Aurantiis.
Embodiment 6 Chinese medicine compositions one
2.8 parts of Herba Artemisiae Scopariaes, 2.8 parts of Herba Lysimachiaes, 2 parts of Rhizoma Polygoni Cuspidati, 1 part of Radix Curcumae, 1.5 parts of the Radix Aucklandiae, 1 part of living Fructus Aurantii.
Embodiment 7 Chinese medicine compositions one
3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis.
Embodiment 8 Chinese medicine compositions one
3.2 parts of Herba Artemisiae Scopariaes, 2.6 parts of Herba Lysimachiaes, 1.9 parts of Rhizoma Polygoni Cuspidati, 1.1 parts of Radix Curcumaes, 1.4 parts of the Radix Aucklandiae, 1.1 parts of living Fructus Aurantiis.
Embodiment 9 Chinese medicine compositions one
3.4 parts of Herba Artemisiae Scopariaes, 2.5 parts of Herba Lysimachiaes, 1.7 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.5 parts of the Radix Aucklandiae, 1.3 parts of living Fructus Aurantiis.
Embodiment 10 Chinese medicine compositions one
3.5 parts of Herba Artemisiae Scopariaes, 2.4 parts of Herba Lysimachiaes, 1.6 parts of Rhizoma Polygoni Cuspidati, 1.3 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.4 parts of living Fructus Aurantiis.
Embodiment 11 Chinese medicine compositions one
3.8 parts of Herba Artemisiae Scopariaes, 2.2 parts of Herba Lysimachiaes, 1.5 parts of Rhizoma Polygoni Cuspidati, 1.4 parts of Radix Curcumaes, 1.1 parts of the Radix Aucklandiae, 1.5 parts of living Fructus Aurantiis.
Embodiment 12 Chinese medicine compositions one
4 parts of Herba Artemisiae Scopariaes, 2 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.5 parts of Radix Curcumaes, 1 part of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis.
The present invention also provides a kind of Chinese medicine composition two for the treatment of cholecystitis and cholelithiasis, is made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part, Herba Hedyotidis Corymbosae 2-4 part, Radix Et Rhizoma Rhei 0.1-0.5 part, Stigma Maydis 2-4 part.
Embodiment 13 Chinese medicine compositions two
2 parts of Herba Artemisiae Scopariaes, 4 parts of Herba Lysimachiaes, 1.5 parts of Rhizoma Polygoni Cuspidati, 1.5 parts of Radix Curcumaes, 1 part of the Radix Aucklandiae, 1.5 parts of living Fructus Aurantiis, 2 parts in Herba Hedyotidis Corymbosae, 0.5 part of Radix Et Rhizoma Rhei, 2 parts of Stigma Maydis.
Embodiment 14 Chinese medicine compositions two
2.2 parts of Herba Artemisiae Scopariaes, 3.7 parts of Herba Lysimachiaes, 1.6 parts of Rhizoma Polygoni Cuspidati, 1.4 parts of Radix Curcumaes, 1.1 parts of the Radix Aucklandiae, 1.4 parts of living Fructus Aurantiis, 2.2 parts in Herba Hedyotidis Corymbosae, 0.4 part of Radix Et Rhizoma Rhei, 2.2 parts of Stigma Maydis.
Embodiment 15 Chinese medicine compositions two
2.4 parts of Herba Artemisiae Scopariaes, 3.5 parts of Herba Lysimachiaes, 1.7 parts of Rhizoma Polygoni Cuspidati, 1.3 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.3 parts of living Fructus Aurantiis, 2.4 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 2.4 parts of Stigma Maydis.
Embodiment 16 Chinese medicine compositions two
2.5 parts of Herba Artemisiae Scopariaes, 3.4 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.3 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis, 2.5 parts in Herba Hedyotidis Corymbosae, 0.2 part of Radix Et Rhizoma Rhei, 2.5 parts of Stigma Maydis.
Embodiment 17 Chinese medicine compositions two
2.6 parts of Herba Artemisiae Scopariaes, 3.2 parts of Herba Lysimachiaes, 1.9 parts of Rhizoma Polygoni Cuspidati, 1.1 parts of Radix Curcumaes, 1.4 parts of the Radix Aucklandiae, 1.1 parts of living Fructus Aurantiis, 2.6 parts in Herba Hedyotidis Corymbosae, 0.1 part of Radix Et Rhizoma Rhei, 2.6 parts of Stigma Maydis.
Embodiment 18 Chinese medicine compositions two
2.8 parts of Herba Artemisiae Scopariaes, 2.8 parts of Herba Lysimachiaes, 2 parts of Rhizoma Polygoni Cuspidati, 1 part of Radix Curcumae, 1.5 parts of the Radix Aucklandiae, 1 part of living Fructus Aurantii, 2.8 parts in Herba Hedyotidis Corymbosae, 0.2 part of Radix Et Rhizoma Rhei, 2.8 parts of Stigma Maydis.
Embodiment 19 Chinese medicine compositions two
3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis, 3 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 3 parts of Stigma Maydis.
Embodiment 20 Chinese medicine compositions two
3.2 parts of Herba Artemisiae Scopariaes, 2.6 parts of Herba Lysimachiaes, 1.9 parts of Rhizoma Polygoni Cuspidati, 1.1 parts of Radix Curcumaes, 1.4 parts of the Radix Aucklandiae, 1.1 parts of living Fructus Aurantiis, 3.2 parts in Herba Hedyotidis Corymbosae, 0.4 part of Radix Et Rhizoma Rhei, 3.2 parts of Stigma Maydis.
Embodiment 21 Chinese medicine compositions two
3.4 parts of Herba Artemisiae Scopariaes, 2.5 parts of Herba Lysimachiaes, 1.7 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.5 parts of the Radix Aucklandiae, 1.3 parts of living Fructus Aurantiis, 3.4 parts in Herba Hedyotidis Corymbosae, 0.5 part of Radix Et Rhizoma Rhei, 3.4 parts of Stigma Maydis.
Embodiment 22 Chinese medicine compositions two
3.5 parts of Herba Artemisiae Scopariaes, 2.4 parts of Herba Lysimachiaes, 1.6 parts of Rhizoma Polygoni Cuspidati, 1.3 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.4 parts of living Fructus Aurantiis, 3.5 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 3.5 parts of Stigma Maydis.
Embodiment 23 Chinese medicine compositions two
3.8 parts of Herba Artemisiae Scopariaes, 2.2 parts of Herba Lysimachiaes, 1.5 parts of Rhizoma Polygoni Cuspidati, 1.4 parts of Radix Curcumaes, 1.1 parts of the Radix Aucklandiae, 1.5 parts of living Fructus Aurantiis, 3.8 parts in Herba Hedyotidis Corymbosae, 0.2 part of Radix Et Rhizoma Rhei, 3.8 parts of Stigma Maydis.
Embodiment 24 Chinese medicine compositions two
4 parts of Herba Artemisiae Scopariaes, 2 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.5 parts of Radix Curcumaes, 1 part of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis, 4 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 4 parts of Stigma Maydis.
The preparation of embodiment 25 Chinese medicine composition decoctions
Adopt the manufacture method of Chinese medicine decoction routine, namely get the arbitrary described Chinese medicine composition of embodiment 1-24 and decoct with water into decoction.
The preparation of embodiment 26 Chinese medicine composition tablets/capsules
Get the arbitrary described Chinese medicine composition of embodiment 1-24, add 6-10 times of water gaging, decocted 1-3 hour, leach medicine juice.Add 6-10 times of water gaging again, decocted 0.5-2 hour, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds concentrated solution 2-3 and doubly measures ethanol, stirs precipitation and spends the night.Get supernatant, be concentrated into thick extractum; Add pharmaceutical aids, vacuum drying is pulverized and is granulated, and is pressed into tablet or fills encapsulated.
The preparation of embodiment 27 Chinese medicine composition composition granules
Get the arbitrary described Chinese medicine composition of embodiment 1-24, add 10 times of water gagings, decocted 2 hours, leach medicine juice.Add 8 times of water gagings again, decocted 1 hour, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds 2 times of amounts of concentrated solution ethanol, stirs precipitation and spends the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids, granulate, drying, granulate gets granule, packing 5g/ bag.
The preparation of embodiment 28 Chinese medicine composition mixture/oral liquid/syrups
Get the arbitrary described Chinese medicine composition of embodiment 1-24, add 10 times of water gagings, decocted 2 hours, leach medicine juice.Add 8 times of water gagings again, decocted 1 hour, leach medicine juice, merge the secondary decocting liquid, leave standstill, the leaching supernatant concentrates, and puts coldly, adds 2 times of amounts of concentrated solution ethanol, stirs precipitation and spends the night.Get supernatant, be concentrated into thick extractum; Add suitable pharmaceutical aids (white sugar, Mel, benzene first propanoic acid or ethyl hydroxybenzoate etc.), make mixture, oral liquid or syrup.
The clinical experiment of embodiment 29 traditional Chinese medicine composition for treating cholecystitis and cholelithiasis
1 data and method
1.1 physical data
Cholecystitis and cholelithiasis patient 150 examples of selecting 2010-2011 hospital's Gastroenterology dept.'s outpatient service and in-patient department to go to a doctor all meet " new Chinese medicine clinical research guideline " and determine diagnosis.Include standard in: meet the patient of chronic cholecystitis diagnosis and Chinese medical discrimination standard, can include the test case in.Exclusion standard: (1) does not meet the standard of including in; (2) discomforts such as side of body rib distension pain of being brought out by factors such as medicine or other diseases.(3) merge to have the inclination, serious diseases such as brain, lung, kidney.(4) gestation or women breast-feeding their children are to this medicine allergy sufferers.(5) serious symptom cholecystitis: acute suppuration cholecystitis, acute gangrenous cholecystitis, acute obstructive suppurative cholangitis, the concurrent diffuse peritonitis person of perforation of gallbladder.(6) take other similar medicine persons simultaneously.
150 examples are included the patient in, by the table of random number method, are divided into one group for the treatment of, treatment two groups and matched group with the 2:2:1 ratio:
Treat one group of 60 example, 1 example that comes off, totally 59 examples, male's 30 examples, women's 29 examples, 18-29 year 13 people, 30-49 year 27 people, 50-65 year 19 people, patient's course of disease＜1 year 11 people, 1-5 28 people, 5-10 20 people;
Treat two group of 60 example, 1 example that comes off, totally 59 examples, male's 31 examples, women's 28 examples, 18-29 year 12 people, 30-49 year 28 people, 50-65 year 19 people, patient's course of disease＜1 year 10 people, 1-5 30 people, 5-10 19 people;
Matched group 30 examples, 2 examples that come off, totally 28 examples, male's 15 examples wherein, women's 13 examples, 18-29 year 5 people, 30-49 year 13 people, 50-65 year 10 people, patient's course of disease＜1 year 4 people, 1-5 14 people, 5-10 10 people.Three groups of case physical data (sex, age, the course of disease) comparing difference not statistically significant.
1.2 Therapeutic Method
Treat one group of oral Chinese medicine compositions one (with reference to embodiment 7 and 25 preparations), every day 2-4 time; Treat two groups of oral Chinese medicine compositionss two (with reference to embodiment 19 and 25 preparations), every day 2-4 time; The oral DANNING PIAN of matched group (already being produced main component Radix Et Rhizoma Rhei, Rhizoma Polygoni Cuspidati, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, Radix Curcumae, Fructus Crataegi, Rhizoma Imperatae by Shanghai and xanthate), 5/time, every day three times.Treated for 8 weeks.Period in a medicine is avoided greasy, zest diet, work and rest rule.
1.3 observation index and method
1.3.1 clinical symptoms integral estimation: carry out the clinical symptoms integral estimation before the treatment one time, the back is weekly.
1.3.2 lab index: hematuria stool routine, electrocardiogram, B ultrasonic and ALT, serum creatinine.Contained item inspection once carries out ALT, serum creatinine inspection around the back is every before the treatment, finishes back check hematuria stool routine, electrocardiogram and B ultrasonic the course for the treatment of.B ultrasonic result before and after the contrast therapy observes the change of calculus size, gallbladder wall thickness.
1.4 criterion of therapeutical effect
Formulate with reference to " new Chinese medicine clinical research principle ".Recovery from illness: after finishing the course for the treatment of, symptom and sign disappears, and ultrasound diagnosis gallbladder size and wall thickness are normal; Produce effects: after finishing the course for the treatment of, symptom integral reduces 2 grades, and ultrasound diagnosis gallbladder size and wall thickness obviously improve; Effectively: after finishing the course for the treatment of, symptom integral reduces 1 grade, and ultrasound diagnosis gallbladder size and wall thickness have improvement; Invalid: do not reach above-mentioned standard person, ultrasound diagnosis gallbladder size still increases, wall thickness, crude.
1.5 statistical method
Adopt the SPSS15.0 statistical software to carry out computational analysis, measurement data adopts the t check, and enumeration data adopts X 2 test, and there is statistical significance P＜0.05 for difference.
2 results
2.1 therapeutic evaluation treat behind one group, treatment two groups and treatment of control group clinical efficacy by statistics credit analyse, three groups curative effect difference has statistical significance (P＜0.05), treats one group and treatment and is better than matched group (table 1) for two groups.
The comparison of three groups of clinical efficacies of table 1 [example (%)]
| Group | The example number | Produce effects | Effectively | Invalid | Total effective rate (%) |
| Treat one group | 59 | 34（57.6） | 19（32.2） | 6（10.2） | 89.8 |
| Treat two groups | 59 | 41（70.0） | 15（24.8） | 3（5.2） | 94.8 |
| Matched group | 28 | 15（55.8） | 7（23.6） | 6（20.6） | 79.4 |
2.2 untoward reaction: three groups untoward reaction all do not occur during treating.
3 discuss
Modern medicine thinks that cholecystitis is many because the infection of antibacterial and virus, obstruction of bile duct or pancreatic juice cause that to chemical factors such as the anti-streams of biliary tract the gallbladder inflammation sexually transmitted disease (STD) becomes, biliary drainage is not smooth, bile that concentrate stimulates gallbladder mucosa, cause secretion to increase, intracavity is pressed and is increased, gall bladder emptying postpones in addition, self purification weakens the infringement that has more increased the weight of cyst wall, thereby more is conducive to the growth of antibacterial, so vicious cycle.
Motherland's medical science claims that gallbladder is " extraordinary Fu-organ ", has " full and unreal, also hide also rush down ", is suitable characteristics with logical, think " receptor of institute at his mansion, all to turbid thing, only gallbladder then be subjected to the five internal organs refined juice also ".Though do not have " cholecystitis ", according to its symptom, it can be attributed to motherland's medical science " gallbladder-distention ", " hypochondriac pain " category.Jing-Yue Complete Works is pointed out: " so disease of hypochondriac pain, this genus liver and gall two warps with the arteries and veins of two warps, all follow the side of body also." " Ling Shu Miraculous Pivot or Divine Axis expands and discusses " " gallbladder-distention person, pain over the hypochondrium expands, and is bitter in mouthful, sighing frequently ".How the sick position of primary disease causes disorder of QI movement by the exopathogen internal injury in liver and gall, and QI stagnation of the liver and galibladder is violated and taste, and transporting and transforming function of the spleen and stomach is unfavorable, and endogenous damp formation is strongly fragrant in the damp, and for a long time and heat-transformation, damp-heat accumulation hinders in side of body network.The present invention's research is accumulating rich experience aspect treatment chronic cholecystitis, the cholelithiasis, think gallbladder-heat pent-up, it is the important pathogenesis of this disease that irritability is not dredged, treatment should be based on clearing heat secreting bile, dispersing the stagnated live-QI to relieve the stagnation of QI, sum up Chinese medicine composition one of the present invention and Chinese medicine composition two as the experience prescription for the treatment of primary disease, contained Herba Lysimachiae has the Huang of dispelling that helps digestion in the side, the effect of clearing away heat-damp and promoting diuresis.The logical intestinal of internal organs falls in Radix Et Rhizoma Rhei energy clearing away heat-fire.Herba Artemisiae Scopariae clearing away damp-heat, jaundice eliminating subcutaneous ulcer.Above-mentioned Chinese medicine still can promote bile secretion, increases bile solids, bile acid and bilirubinic output.Result of study of the present invention shows that Chinese medicine composition one of the present invention and Chinese medicine composition two treatment cholecystitis and cholelithiasis determined curative effects can improve symptom, alleviate the patient suffering.Medication is convenient, is worthy to be popularized.
The above only is preferred implementation of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the inventive method; can also make some improvement and replenish, these improvement and replenish and also should be considered as protection scope of the present invention.
Claims (7)
1. Chinese medicine composition for the treatment of cholecystitis and cholelithiasis, it is characterized in that described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part.
2. Chinese medicine composition according to claim 1, it is characterized in that described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2.5-3.5 part, Herba Lysimachiae 2.5-3.5 part, Rhizoma Polygoni Cuspidati 1.7-1.9 part, Radix Curcumae 1.1-1.3 part, Radix Aucklandiae 1.1-1.3 part, living Fructus Aurantii 1.1-1.3 part.
3. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition is made by following bulk drugs: 3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis.
4. Chinese medicine composition for the treatment of cholecystitis and cholelithiasis, it is characterized in that described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2-4 part, Herba Lysimachiae 2-4 part, Rhizoma Polygoni Cuspidati 1.5-2 part, Radix Curcumae 1-1.5 part, Radix Aucklandiae 1-1.5 part, living Fructus Aurantii 1-1.5 part, Herba Hedyotidis Corymbosae 2-4 part, Radix Et Rhizoma Rhei 0.1-0.5 part, Stigma Maydis 2-4 part.
5. Chinese medicine composition according to claim 4, it is characterized in that described Chinese medicine composition is made by following bulk drugs: Herba Artemisiae Scopariae 2.5-3.5 part, Herba Lysimachiae 2.5-3.5 part, Rhizoma Polygoni Cuspidati 1.7-1.9 part, Radix Curcumae 1.1-1.3 part, Radix Aucklandiae 1.1-1.3 part, living Fructus Aurantii 1.1-1.3 part, Herba Hedyotidis Corymbosae 2.5-3.5 part, Radix Et Rhizoma Rhei 0.2-0.4 part, Stigma Maydis 2.5-3.5 part.
6. Chinese medicine composition according to claim 4, it is characterized in that described Chinese medicine composition is made by following bulk drugs: 3 parts of Herba Artemisiae Scopariaes, 3 parts of Herba Lysimachiaes, 1.8 parts of Rhizoma Polygoni Cuspidati, 1.2 parts of Radix Curcumaes, 1.2 parts of the Radix Aucklandiae, 1.2 parts of living Fructus Aurantiis, 3 parts in Herba Hedyotidis Corymbosae, 0.3 part of Radix Et Rhizoma Rhei, 3 parts of Stigma Maydis.
7. according to the application of the arbitrary described Chinese medicine composition of claim 1-6 in the medicine of preparation treatment cholecystitis and cholelithiasis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310136671.6A CN103230566B (en) | 2013-04-19 | 2013-04-19 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310136671.6A CN103230566B (en) | 2013-04-19 | 2013-04-19 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103230566A true CN103230566A (en) | 2013-08-07 |
| CN103230566B CN103230566B (en) | 2014-11-26 |
Family
ID=48878681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310136671.6A Active CN103230566B (en) | 2013-04-19 | 2013-04-19 | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103230566B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104547721A (en) * | 2015-02-05 | 2015-04-29 | 王昌荣 | Traditional Chinese medicine for treating cholecystitis |
| CN104606620A (en) * | 2015-02-01 | 2015-05-13 | 徐鸿刚 | Traditional Chinese medicine for treating cholecystitis |
| CN109224034A (en) * | 2018-11-13 | 2019-01-18 | 谭龙 | A kind of Hepatoprotective cholagogue Nieron Capsules and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150041A (en) * | 1996-09-24 | 1997-05-21 | 秦应中 | Chinese patent medicine for curing gallstones and kidney stones |
| CN101274087A (en) * | 2008-05-14 | 2008-10-01 | 刘庆常 | Chinese medicine decoction for invigorating gallbladder and removing gall-stone |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150041C (en) * | 2000-09-26 | 2004-05-19 | 兴运实业（成都）有限公司 | Multi-source infrared energy therapy room |
-
2013
- 2013-04-19 CN CN201310136671.6A patent/CN103230566B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1150041A (en) * | 1996-09-24 | 1997-05-21 | 秦应中 | Chinese patent medicine for curing gallstones and kidney stones |
| CN101274087A (en) * | 2008-05-14 | 2008-10-01 | 刘庆常 | Chinese medicine decoction for invigorating gallbladder and removing gall-stone |
Non-Patent Citations (1)
| Title |
|---|
| 刘志勇: "利胆法在胃肠病治疗中的应用体会", 《河北中医》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104606620A (en) * | 2015-02-01 | 2015-05-13 | 徐鸿刚 | Traditional Chinese medicine for treating cholecystitis |
| CN104547721A (en) * | 2015-02-05 | 2015-04-29 | 王昌荣 | Traditional Chinese medicine for treating cholecystitis |
| CN109224034A (en) * | 2018-11-13 | 2019-01-18 | 谭龙 | A kind of Hepatoprotective cholagogue Nieron Capsules and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103230566B (en) | 2014-11-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101700358A (en) | Medicine for treating acute and chronic nonspecific ulcerative colitis and preparation method thereof | |
| CN103007206A (en) | Oral liquid for treating chronic atrophic gastritis | |
| CN104587381B (en) | A kind of Chinese medicine preparation for the treatment of chronic cholecystitis | |
| CN103230566B (en) | Traditional Chinese medical composition for treating cholecystitis cholelithiasis and application thereof | |
| CN102423423A (en) | Traditional Chinese medicine for treating urinary tract infection | |
| CN104225218A (en) | Traditional Chinese medicine preparation for chronic urinary infection treatment | |
| CN103784932A (en) | Traditional Chinese medicine decoction for treating hyperplasia of mammary glands | |
| CN101073648A (en) | Method for treating senile constipation | |
| CN102973696B (en) | Traditional Chinese medicine composition for treating chronic enteritis and preparation method of traditional Chinese medicine composition | |
| CN102205068A (en) | Medicament for treating chronic ulcerative colitis and preparation method thereof | |
| CN100577199C (en) | Application of stomachic pill with cyperus and amomum | |
| CN104524085A (en) | Drug for treatment of primary dysmenorrhea | |
| CN103845689A (en) | External application medicine for treating benign prostatic hyperplasia | |
| CN102302744A (en) | Chinese medicinal preparation for treating chronic cholecystitis | |
| CN103520638B (en) | A kind of Traditional Chinese medicine compound composition for the treatment of prostate hyperplasia and preparation method thereof and application thereof | |
| CN102988945B (en) | Traditional Chinese medicine prescription for treating enteritis | |
| CN102836403B (en) | Chinese medicine for treating chronic nephritis by using root of low greenbrier | |
| CN102228661B (en) | Chinese medicinal cholecystitis treatment mixture for treating chronic cholecystitis | |
| CN101987162B (en) | Traditional Chinese medical preparation for treating anaphylatic purpura nephritis nephrotic syndrome | |
| CN103263516B (en) | Medicine for treating cholecystitis | |
| CN102423454A (en) | Chinese medicinal preparation for treating chronic cholecystitis | |
| CN104001077A (en) | Traditional Chinese medicine composition for treating urinary tract infection and application thereof | |
| CN105168879A (en) | Traditional Chinese medicine for treating ulcerative colitis | |
| CN103585506B (en) | A kind of Chinese medicinal enema for the treatment of infantile autumn diarrhea | |
| CN104367862A (en) | Traditional Chinese medicinal composition for treating urethral calculus |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |