CN102091296B - Medicament for treating breast hyperplasia - Google Patents
Medicament for treating breast hyperplasia Download PDFInfo
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- CN102091296B CN102091296B CN2011100247481A CN201110024748A CN102091296B CN 102091296 B CN102091296 B CN 102091296B CN 2011100247481 A CN2011100247481 A CN 2011100247481A CN 201110024748 A CN201110024748 A CN 201110024748A CN 102091296 B CN102091296 B CN 102091296B
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Abstract
The invention discloses a medicament for treating breast hyperplasia, belonging to the technical field of Chinese traditional medicines. Angelica, white peony root, safflower, prepared rehmannia root, spatholobus stem, chuanxiong rhizome, notopterygium root, radix angelicae, dangshen, milk vetch, honeysuckle, licorice, sealwort, corydalis tuber, rhizoma cyperi, mastic, myrrh, peach kernel, self-heal, dandelion, spina gleditsiae, common burreed rhizome, rhizoma zedoariae, radix sileris, cowherb seed and crow pheasant are used as raw materials; and the raw materials are added into the white wine the concentration of which is 50 for soaking for 90-100 days to be prepared into a traditional Chinese medicine wine, wherein the mass ratio of the raw medicines to the wine is 1:8. The medicament disclosed by the invention is a traditional Chinese medicine preparation which is prepared according to the traditional Chinese medicine theory, has reasonable medical combination, has the functions of supplementing qi and activating blood circulation, and can be used for treating both principal and secondary aspects of the disease. Proven by clinical observation of patients for many years, the medicament disclosed by the invention has an obvious treatment effect.
Description
Technical field the invention belongs to technical field of pharmaceuticals, relates to a kind of medicine of treating cyclomastopathy, is the oral Chinese medicine wine of feedstock production specifically with the Chinese herbal medicine.
Background technology lump in breast and pain are the main feature of cyclomastopathy, and breast often has distending pain, twinge, takes out pain, and patient's pain appears at before the menstruation arriving mostly; The patient's chest that also has continues irregular pain; Sometimes takeing on back, upper limb also has acid, bloated pain symptom, and lump in breast is in a side or the bilateral breast, and lump size, hardness can change with menstrual cycle; Pain increases the weight of when pushing, sometimes from nipple trickle etc.Cause the cause of disease of cyclomastopathy that following several kinds of situations are arranged: 1. estrogen secretion is disorderly; The breast disease age occurred frequently is the 40-60 women in year; This age bracket is women's estrogen secretion imbalance estrogen level higher period just; Because the secretion increasing of body inner estrogen, can make the hyperplasia of the chrotoplast on the breast duct like this and breast lesion takes place; 2. fertility and lactication prove through a large amount of investigation in recent years, do not give birth to or to have had the women who gives birth to seldom lactication that the breast disease women longer than repeatedly lactication, lactication time take place many; 3. inherited genetic factors has mainly shown on the breast disease family history, and common have two kinds of hereditary situation, and mother suffers from breast disease; Daughter also possibly change breast disease, and this breast disease mostly occurs before amenorrhea, often is bilateral property; Another kind was not suffered from breast disease for mother, but in one family, had at least two sisters to suffer from breast disease; Mastotic sickness rate is higher 2 to 3 times than sickness rate in the family of no family history in this family, and this breast disease mostly occurs after amenorrhea, often is one-sided property.The early stage judgement and the diagnostic criteria of clinical cyclomastopathy are: 1. breast often has local discomfort, particularly postclimacteric women, and it is uncomfortable to feel that sometimes a side breast mild pain is uncomfortable or a side shoulder is sent out heavy, acid is expanded, even leads and the upper arm of this side; 2. can touch the lump of Semen Viciae fabae size in the breast, harder, movable, there is not obvious pain, the X line is taken the photograph the visible lump of sheet; 3. the breast profile changes; 4. bounce back with nipple; 5. nipple discharge, especially discharge are the color serosity; 6. regional lymph enlargement.Cyclomastopathy is a common clinical, frequently-occurring disease.At present, the treatment cyclomastopathy is Western medicine antibiotic or operative treatment mostly.The side effect that the long-term excessive use of medicine of western medicine cyclomastopathy is brought is obvious to all, directly influences people's physical and mental health, directly brings spirit and burden economically for patient and family; The operative treatment patient suffering is big, medical expense is high.
Summary of the invention the purpose of this invention is to provide a kind of reducing swelling and alleviating pain, the medicine of active treatment cyclomastopathy of promoting blood circulation.
The objective of the invention is according to pathogenetic understanding and the Therapeutic Principle thereof of motherland's traditional medicine cyclomastopathy; With reference to modern pharmacological research; Therefrom filter out reducing swelling and alleviating pain, the demountable natural Chinese medicinal herb of promoting blood circulation and Chinese liquor compatibility, press the Chinese medical theory prescription, make the unobstructed effect of its performance meridians.
Medicine of the present invention is the medicated wine of being processed by following raw material medicaments: Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 10g, Flos Carthami 5g, Radix Rehmanniae Preparata 25g, Caulis Spatholobi 30g, Rhizoma Chuanxiong 25g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Dahuricae 25g, Radix Codonopsis 25g, Radix Astragali 30g, Flos Lonicerae 10g, Radix Glycyrrhizae 10g, Rhizoma Polygonati 25g, Rhizoma Corydalis 10g, Rhizoma Cyperi 15g, Olibanum 10g, Myrrha 10g, Semen Persicae 10g, Spica Prunellae 20g, Herba Taraxaci 20g, Spina Gleditsiae 5g, triangular 20g, Rhizoma Curcumae 20g, windproof 10g, Semen Vaccariae 10g, Centropus sinensis (Stephens) 30g; Processed Chinese medicinal liquor in 90-100 days with soaking in above-mentioned each component adding 50 degree Chinese liquor, the mass ratio of crude drug and wine is 1: 8.
Chinese medicinal liquor of the present invention, name for: the breast that disappears increases oral liquid.Radix Angelicae Sinensis acrid in the mouth wherein is warm in nature, enriches blood and invigorates blood circulation; The acid of Radix Paeoniae Alba bitter in the mouth, cold nature has the kind cloudy blood tonification effect of convergence; The Flos Carthami acrid in the mouth is warm in nature, the blood stasis expelling effect of invigorating blood circulation; Radix Rehmanniae Preparata sweet-bitter flavor tepor, kidney nourishing and blood enriching; Caulis Spatholobi bitter in the mouth tepor, the promoting blood circulation to remove obstruction in the collateral effect of enriching blood; The Rhizoma Chuanxiong acrid in the mouth is warm in nature, the blood stasis expelling of invigorating blood circulation, wind-expelling pain-stopping effect; Rhizoma Et Radix Notopterygii acrid in the mouth tepor, relaxing muscles and tendons and activating QI and blood in the collateral, dispersing wind and cold dehumidifying; Radix Angelicae Dahuricae acrid in the mouth tepor, the evacuation of pus of invigorating blood circulation, dispersing wind and cold; Radix Codonopsis sweet in the mouth property is flat, invigorating the spleen and replenishing QI, slakes thirst and help produce saliva; Radix Astragali sweet in the mouth is warm in nature, QI invigorating hidroschesis, holder hypergene flesh; The Flos Lonicerae acrid in the mouth is cold in nature, control the pain pestilence from the beginning of, enrich blood; Radix Glycyrrhizae sweet in the mouth cold nature, invigorating the spleen and replenishing QI; Rhizoma Polygonati sweet in the mouth property is flat, spleen reinforcing lung moistening, supplementing QI for promoting the production of body fluid; Rhizoma Corydalis acrid in the mouth bitterness temperature, eliminating stasis to stop pain; Rhizoma Cyperi acrid in the mouth property is flat, and regulating the flow of vital energy, separating becomes silted up controls the lump in breast pain; The Olibanum acrid in the mouth is bitter, warm in nature, blood circulation promoting regulates qi, pain relieving granulation promoting; Myrrha bitter in the mouth property is flat, and reducing swelling and alleviating pain, to control congestion not all right; Semen Persicae bitter in the mouth property is flat, the removing blood stasis blood stasis expelling, controls the congestion lump; The Spica Prunellae acrid in the mouth is cold in nature, liver heat removing, eliminating stagnation, diuresis; Control that pestilence, acute mastitis, ophthalmalgia, jaundice, gonorrhea, hypertension, lymphoid tuberculosis, thyromegaly, scrofula, goiter, acute mastitis, breast carcinoma, order pearl nyctalgia, photophobia are shed tears, the vertigo, facial hemiparalysis, bones and muscles pain, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, all diseases of leukorrhagia; The Herba Taraxaci sweet in the mouth is cold in nature, and heat-clearing and toxic substances removing, promoting the circulation of blood collateral dredging, eliminating carbuncle eliminating stagnation treatment pyretic toxicity are stopped up the carbuncle sore tumefacting virus of tying due to the muscle, and acute mastitis is had good effect, can the detoxicating and resolving stagnation of pathogens lactogenesis; The Spina Gleditsiae acrid in the mouth is warm in nature, is apt to attack diffusing, reducing swelling and alleviating pain; Triangular bitter in the mouth property is flat, and removing blood stasis with potent drugs blood, detumescence are amassed, removing blood stasis is cut heavily fortified point; The Rhizoma Curcumae bitter in the mouth is warm in nature, and QI invigorating dissipating blood stasis piece, removing blood stasis are cut heavily fortified point; Windproof sweet in the mouth is warm in nature, Pulvis Diaphoreticus wind and cold, dehumidifying; Semen Vaccariae sweet in the mouth bitterness is flat, promoting blood circulation to restore menstrual flow; Centropus sinensis (Stephens) has the blood circulation promoting and enriching function; The Chinese liquor promoting blood circulation to remove obstruction in the collateral.Above-mentioned all medicines have specially good effect through reasonable compatibility to the treatment cyclomastopathy.
The present invention disappears, and to increase oral liquid be Chinese medicine preparation to breast, according to the theory of Chinese medical science prescription, select medicine rationally, QI invigorating, enrich blood, blood circulation promoting and blood stasis dispelling, the hard eliminating stagnation of change, alleviating pain and detumescence, treating both the principal and secondary aspects of a disease.Year clinical observation patient surplus the medicine of the present invention, warp 20, evident in efficacy, the cyclomastopathy patient that a variety of causes is caused has remarkable result.
The present invention's breast that disappears increases the clinical result of taking of oral liquid and shows that it is raw material that the present invention selects natural plant for use, and each component meets the pharmaceutical control law regulation; Utilize the comprehensive function treatment cyclomastopathy of the medicine of respectively distinguishing the flavor of, no chemicals, harmless to human non-toxic; Have no side effect, safe and reliable; Crude drug steeps with steeping in wine, and effective ingredient scatters and disappears few, and curative effect is high, and is cheap, taking convenience, no any discomfort disease, clinical observation, the medicine of instead other treatment cyclomastopathy.
For showing that the present invention's breast that disappears increases the therapeutic effect of oral liquid to cyclomastopathy; The present invention is through the clinical observation of 100 routine cyclomastopathy patient systems; And select medical history, the state of an illness, age and cyclomastopathy patient 10 examples suitable to organize as a comparison with traditional therapy; 29～65 years old age, course of disease February～1 year.Test group: the conventional medicine of stopping using, take medicine of the present invention; Matched group: take conventional medicine.Observation period is 1 month, checks after half a year, and the present invention's breast that disappears increases the therapeutic evaluation of oral liquid: the thorough rehabilitation of lump disappearance health does not have recurrence and is produce effects, and lump disappears, and painless sb.'s illness took a favorable turn is evident as effectively, and it is not obvious that sb.'s illness took a favorable turn is invalid.
Instructions of taking: a 25g, 2 times on the one, 10 days is a course of treatment.Clinical realization result sees table 1.
Table 1: take the present invention's breast that disappears and increase oral liquid and take the observation of curative effect of conventional medicine to the cyclomastopathy patient.
| Group | Case load | Produce effects (routine number) | Effectively (routine number) | Invalid (routine number) | Total effective rate (%) |
| Test group | 100 | 89 | 11 | 0 | 100 |
| Matched group | 10 | 0 | 8 | 2 | 80.0 |
| T | 2.60 | 2.50 | 2.40 | 3.92 | |
| P | ＜0.05 | ＜0.05 | ＜0.05 | ＜0.05 | ＜0.05 |
Can find out that from table 1 the present invention's breast that disappears increases oral liquid to 100 routine cyclomastopathy patients, obtains 89 examples that have of significant curative effect, accounts for 89.0%; That takes a turn for the better has 11 examples, accounts for 11.0%; Total effective rate reaches 100%.
Model case
1, the king so-and-so, woman, 29 years old, king family government's bank village, Yinan County Yang Jiapo town.On August 10th, 2009 was come the here first visit, and its cyclomastopathy condition of illness of private prosecution is heavier, went to various places hospitalize 2 years to have no resolution.Check that through me breast bilateral lump like chicken egg size, has the tenderness sense.Take the present invention disappear breast increase oral liquid after course of treatment symptom take a turn for the better the lump deliquescing.Second the course of treatment lump disappear basically, the 3rd the lump complete obiteration course of treatment also do not have pain, drug withdrawal is taken the photograph sheet inspection through hospital's X line, lump thoroughly disappears, it is normal that health recovers fully.What the patient was glad says: " treatment in 2 years of my warp spends nearly 3,000 yuan and does not all cure.I am very glad now, have spent 500 yuan of diseases of less than just to cure ".Pay a return visit after 1 year, healthy.So-and-so treated cyclomastopathy in here afterwards with eight, the nine people elder generation that has in village with the king over 20 years, all cured with I " breast that disappears increases oral liquid " of development.
2, my Guo neighbours so-and-so, the man, 57 years old, Zuo Quanzhong village, Yinan County Yang Jiapo town came the here first visit on July 20th, 2008, found the bilateral breast hypertrophy, during discovery such as the lump of pigeon egg size, the tenderness sense was arranged.Take the present invention disappear breast increase oral liquid after course of treatment patient oneself agreed, but outbreak again soon asks that the breast that disappears of a course of treatment of its reason increases the oral dose of oral liquid, he took one month, was the little cause of taking dose.Second course of treatment, require the patient necessarily on request dosage taken orally on 10th, take the photograph the sheet inspection through hospital's X line, lump thoroughly disappears, health recovers normally fully, fully recovers.Pay a return visit after 1 year, healthy.
3, Lee so-and-so, woman 32 years old came the here first visit on May 20th, 2005, right breast has the lump of Semen Viciae fabae size on inspection; Take the present invention's breast that disappears and increase oral liquid after course of treatment, further consultation, the patient oneself agreed, and takes the photograph the sheet inspection through hospital's X line; Lump thoroughly disappears, and health recovers normally fully, recovery from illness.Pay a return visit after 1 year, healthy.
4, Shao so-and-so, woman, 42 years old; The laid-off worker of Yinan County non-staple food company, here first visit on June 11 in 2002, readme county hospital X line is taken the photograph the sheet inspection and is suffered from bilateral breast hypertrophy disease; Through me further consultation symptom bilateral breast hypertrophy such as Ovum Columba livia size lump, can move firmly, the tenderness sense is arranged; Uncomfortable relaxing both alleviated later before menstruation came, and be like this month in and month out.Take the present invention and disappear that breast increases oral liquid course of treatment after hospital's X line is taken the photograph the sheet inspection, lump thoroughly disappears, and health recovers normally fully, fully recovers.Pay a return visit after 1 year, healthy.
5, the king so-and-so, woman, 43 years old, king family government's bank village, Yinan County Yang Jiapo town, peasant.On May 6th, 1989 was come the here first visit, and is bad during readme chest pain fashion, in lump is arranged, angry fatigue is both heavy.There is the big Ovum Columba livia of lump in the breast left side on inspection, can move, and touches pain.Take the present invention disappear breast increase oral liquid after course of treatment symptom take a turn for the better the lump deliquescing; Second the lump lump complete obiteration course of treatment also do not have pain, takes the photograph the sheet inspection through hospital's X line, and lump thoroughly disappears, and it is normal that health recovers fully.
6, a left side so-and-so, woman, 35 years old, Zuo Quanqian village, Yinan County Yang Jiapo town, peasant.Came the here first visit on August 10th, 2010, it is sick that the bilateral breast hypertrophy is suffered from readme, invalid through multi-treatment.Lump is big and hard on inspection, can move, and the tenderness sense is arranged.Take the present invention disappear breast increase oral liquid after course of treatment symptom take a turn for the better not obvious; Lump atrophy deliquescing after second course of treatment; The 3rd the lump lump complete obiteration course of treatment also do not have pain, takes the photograph the sheet inspection through hospital's X line, and lump thoroughly disappears, and it is normal that health recovers fully.
7, Guo so-and-so, woman, 36 years old, the left Quan Hou in Yinan County Yang Jiapo town village, peasant.Came the here first visit on July 16th, 2010, it is sick that the bilateral breast hypertrophy is suffered from readme, through me further consultation symptom bilateral breast hypertrophy such as Ovum Columba livia size lump, can move, and uncomfortable relaxing both alleviated later before menstruation came, and be like this month in and month out.Take the present invention and disappear that breast increases oral liquid course of treatment after hospital's X line is taken the photograph the sheet inspection, lump thoroughly disappears, and health recovers normally fully, fully recovers.Pay a return visit after 1 year, healthy.
8, Guo so-and-so, woman, 40 years old, the left Quan Hou in Yinan County Yang Jiapo town village, peasant.Cyclomastopathy is suffered from February, 209 here first visit, readme, and hospitalize is invalid in Qingdao, takes the present invention's breast that disappears and increases oral liquid after course of treatment; Sx, serve on four courses of treatment again after, take the photograph sheet inspection through hospital's X line; Lump thoroughly disappears, and health recovers normally fully, recovery from illness.Pay a return visit after 1 year, healthy.
The specific embodiment takes by weighing raw material by following proportioning:
Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 10g, Flos Carthami 5g, Radix Rehmanniae Preparata 25g, Caulis Spatholobi 30g, Rhizoma Chuanxiong 25g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Dahuricae 25g, Radix Codonopsis 25g, Radix Astragali 30g, Flos Lonicerae 10g, Radix Glycyrrhizae 10g, Rhizoma Polygonati 25g, Rhizoma Corydalis 10g, Rhizoma Cyperi 15g, Olibanum 10g, Myrrha 10g, Semen Persicae 10g, Spica Prunellae 20g, Herba Taraxaci 20g, Spina Gleditsiae 5g, triangular 20g, Rhizoma Curcumae 20g, windproof 10g, Semen Vaccariae 10g, Centropus sinensis (Stephens) 30g; Processed Chinese medicinal liquor in 95 days with soaking in above-mentioned each component adding 50 degree Chinese liquor, the mass ratio of crude drug and wine is 1: 8.
Claims (1)
1. a medicine of treating cyclomastopathy is characterized in that it is the medicated wine of being processed by following raw material medicaments: Radix Angelicae Sinensis 25g, Radix Paeoniae Alba 10g, Flos Carthami 5g, Radix Rehmanniae Preparata 25g, Caulis Spatholobi 30g, Rhizoma Chuanxiong 25g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Dahuricae 25g, Radix Codonopsis 25g, Radix Astragali 30g, Flos Lonicerae 10g, Radix Glycyrrhizae 10g, Rhizoma Polygonati 25g, Rhizoma Corydalis 10g, Rhizoma Cyperi 15g, Olibanum 10g, Myrrha 10g, Semen Persicae 10g, Spica Prunellae 20g, Herba Taraxaci 20g, Spina Gleditsiae 5g, triangular 20g, Rhizoma Curcumae 20g, windproof 10g, Semen Vaccariae 10g, Centropus sinensis (Stephens) 30g; Processed Chinese medicinal liquor in 90-100 days with soaking in above-mentioned each component adding 50 degree Chinese liquor, the mass ratio of crude drug and wine is 1: 8.
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| CN2011100247481A CN102091296B (en) | 2011-01-24 | 2011-01-24 | Medicament for treating breast hyperplasia |
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| CN2011100247481A CN102091296B (en) | 2011-01-24 | 2011-01-24 | Medicament for treating breast hyperplasia |
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| CN102091296B true CN102091296B (en) | 2012-07-25 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104116796B (en) * | 2014-08-12 | 2016-03-09 | 李海英 | A kind of pharmaceutical composition for the treatment of cyclomastopathy |
| CN107582992A (en) * | 2017-11-08 | 2018-01-16 | 杨小丽 | A kind of medicine for treating lump in breast and preparation method thereof |
| CN108404057A (en) * | 2018-05-24 | 2018-08-17 | 武汉启馨文化传播有限公司 | A kind of exterior-applied medical wine for treating the proliferation of mammary gland |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1951481A (en) * | 2006-10-12 | 2007-04-25 | 张元道 | Medicament for treating cerebral thrombosis |
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| CN1895438B (en) * | 2006-06-21 | 2010-12-08 | 三九医药股份有限公司 | Chinese-medicinal composition for treating cephalagia and its preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1951481A (en) * | 2006-10-12 | 2007-04-25 | 张元道 | Medicament for treating cerebral thrombosis |
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