CN114946871B

CN114946871B - Pesticide composition and application thereof

Info

Publication number: CN114946871B
Application number: CN202110912789.8A
Authority: CN
Inventors: 廖明玮; 李次平; 叶宇平; 杨建江
Original assignee: Foshan Yinghui Crop Science Co Ltd
Current assignee: Foshan Yinghui Crop Science Co Ltd
Priority date: 2021-08-10
Filing date: 2021-08-10
Publication date: 2023-09-15
Anticipated expiration: 2041-08-10
Also published as: CN114946871A

Abstract

The embodiment of the invention relates to a pesticide composition and application thereof, and relates to the field of pesticides, and the pesticide composition is characterized in that active ingredients comprise phosphorus sesquioxide and spirotetramat, wherein the weight ratio of the phosphorus sesquioxide to the spirotetramat is 99:1-1:99, optionally 10:1-1:1, optionally 6:1-2:1, optionally 6:1-4:1, optionally 5:1-4:1, and optionally 4:1. The composition is suitable for controlling pests such as green beans, mangoes, melons and the like, such as thrips, aphids and psyllids, and is especially suitable for controlling mangoes thrips. The two pesticide active ingredients have synergistic effect, and can reduce the total application amount, thereby being more efficient and environment-friendly.

Description

Pesticide composition and application thereof

Technical Field

The invention relates to the field of pesticides, in particular to a pesticide composition and application thereof.

Background

The information disclosed in this background section is only for enhancement of understanding of the general background of the invention and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person of ordinary skill in the art.

The suspension emulsion (suspension emulsions, SE for short) is a preparation in which at least two water-insoluble active ingredients are uniformly dispersed in the form of solid particles and fine liquid beads respectively under the condition of taking water as a continuous phase by means of various auxiliary agents to form a stable suspension emulsion system, namely, a preparation in which the main ingredients consist of a water-insoluble oil phase substance and a solid phase substance, and are emulsified and suspended in water. The suspoemulsion has the double advantages of a suspending agent and an aqueous emulsion. The water replaces a large amount of organic solvent as a carrier, so that the use safety of the product is improved, and the phytotoxicity after the application is greatly reduced; the liquid suspension emulsion has good diffusion in water, and can be directly prepared into spray liquid for use; is an excellent, safe and environment-friendly pesticide water-based preparation. In addition, the suspension emulsion is composed of a plurality of effective active ingredients, and has the advantages of expanding the prevention and treatment spectrum, avoiding the incompatibility of barrel mixing, improving the efficiency and the like. Therefore, it is necessary to develop, produce and use the suspoemulsion products, thereby achieving the purpose of efficiently and safely controlling agricultural diseases and insect pests.

The inhibitor has broad-spectrum and quick-acting effects of killing and stomach poisoning and fumigation. Has strong permeability, stable hydrolysis, low volatility, long lasting period and certain systemic effect. Is suitable for preventing and controlling various pests on rice, cotton, fruit trees, vegetables and soybeans, and is also effective on mites. Oxidation to sulfoxide and sulfone in plant body can raise insecticidal activity.

The spirotetramat is a novel tetronic acid derivative pesticide, and has wide insecticidal spectrum and long lasting period. It is to reduce the reproductive capacity of adults by interfering with the fat biosynthesis of insects, resulting in larval death. Due to the unique action mechanism, the pesticide can effectively control pests with resistance to the existing pesticide, and can be used as an important variety for the resistance management of the nicotine pesticide. Spirotetramat is the only modern pesticide to date with dual inward conduction properties at xylem and phloem. The compound can move up and down in the whole plant body and reach leaf surfaces and bark, so that pests such as lettuce and cabbage on the inner leaves and on the bark of fruits can be prevented and controlled. This unique systemic property protects the new buds, leaves and roots from the growth of eggs and larvae of the pest. The bidirectional systemic conductivity means that the pest has no safe hidden place and the control effect is more thorough.

Disclosure of Invention

Object of the Invention

The invention aims to provide a pesticide composition and application thereof, and solves the problem that the existing pesticide is difficult to comprehensively control plant diseases and insect pests of crops in a high-efficiency and environment-friendly manner.

Solution scheme

In order to achieve the aim of the invention, the embodiment of the invention provides a pesticide composition, active ingredients comprise phosphorus sesquialter and spirotetramat, and the weight ratio of the phosphorus sesquialter to the spirotetramat is 99:1-1:99.

Further, the weight ratio of the fenthion to the spirotetramat is 10:1-1:1, optionally 6:1-2:1, optionally 6:1-4:1, optionally 5:1-4:1, optionally 4:1.

Further, the content of the active ingredient accounts for 10% -80% of the total composition, alternatively 35% -60%, alternatively 50%, and the balance being auxiliary agents.

Further, the auxiliary agent is any one or more of dispersing agent, emulsifying agent, antifreezing agent, thickening agent, preservative, defoaming agent, solvent, wetting agent, disintegrating agent, water and filler.

Further, the pesticide composition is in the form of suspending agent, aqueous emulsion, microemulsion, emulsifiable concentrate, wettable powder, microcapsule suspending agent, water dispersible granule, soluble powder, soluble granule or suspoemulsion.

Further, the pesticide composition is in the form of a suspension emulsion, and optionally, the auxiliary agent comprises medium oil, a wetting dispersant, an emulsifier, a thickener, an anti-freezing agent, a stabilizer, an antifoaming agent, a preservative and water.

Further, the mass fractions of the auxiliary agent in the composition are respectively as follows: 0.5-20% of medium oil, 3-15% of wetting dispersant, 1-10% of emulsifier, 0.1-3% of thickener, 1-5% of antifreeze agent, 0.1-10% of stabilizer, 0.1-2% of defoamer, 0.1-1.5% of preservative and water which are added to 100%.

Further, the mass fractions of the auxiliary agent in the composition are respectively as follows: 1-13% of medium oil, 8-15% of wetting dispersant, 3-10% of emulsifier, 0.1-0.2% of thickener, 4-5% of antifreeze agent, 2-5% of stabilizer, 0.1-0.2% of defoamer, 0.1-1.5% of preservative and water which are added to 100%.

Further, the medium oil is selected from vegetable oil, mineral oil and/or paraffin oil.

Further, the wetting dispersant is one or more selected from sodium dodecyl benzene sulfonate, nekal, dodecyl polyoxyethylene ether phosphate, nonylphenol polyoxyethylene ether, potassium oleate, sodium lignin sulfonate, sodium laureth sulfate and alkyl naphthalene formaldehyde condensate sulfonate.

Further, the emulsifier is selected from one or more of high molecular EO-PO block copolymer, NP series nonylphenol polyoxyethylene ether, alkylphenol polyoxyethylene polyether and sulfate or phosphate thereof, AEO series fatty alcohol polyoxyethylene ether, nonylphenol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate phosphate, styrene phenol formaldehyde resin polyoxyethylene ether phosphate, styrylphenol polyoxyethylene polyoxypropylene ether, sodium lignin sulfonate, span series and Tween series.

Further, the thickener is selected from one or more of xanthan gum, acacia, carboxymethyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, methyl cellulose and polyvinyl alcohol.

Further, the antifreeze agent is selected from one or more of ethylene glycol, glycerol, propylene glycol, polyethylene glycol and sorbitol or urea.

Further, the stabilizer is one or more selected from epoxidized soybean oil, linseed oil, citric acid and sodium sorbate.

Further, the defoamer is one or more selected from organosilicon defoamer, C8-C10 fatty alcohol compound or II-ethyl alcohol.

Further, the preservative is one or more selected from sodium benzoate, benzoic acid and sodium diacetate.

Preferably, the pesticide composition comprises the following raw materials in percentage by mass: 30-50% of benfofos, 5-10% of spirotetramat, 1-13% of medium oil, 8-15% of wetting dispersant, 3-10% of emulsifier, 0.1-0.2% of thickener, 4-5% of antifreeze agent, 2-5% of stabilizer, 0.1-0.2% of defoamer, 0.1-1.5% of preservative and water which are added to 100%.

A preferred embodiment is: the pesticide composition comprises the following raw materials in percentage by mass: 40% of phosphorus sesquisulfate, 10% of spirotetramat, 5% of mineral oil, 10% of sodium dodecyl benzene sulfonate, 5% of EO-PO block copolymer, 4% of propylene glycol, 0.1% of hydroxyethyl cellulose, 0.5% of benzoic acid, 0.1% of organosilicon, 2% of linseed oil and 100% of deionized water.

On the other hand, the preparation method of the pesticide composition is provided, the fenthion, the spirotetramat and the auxiliary agent are uniformly mixed according to the corresponding proportion, and continuous sanding is carried out through a sand mill, so that the D90 particle size is less than 5 mu m, and the pesticide suspoemulsion containing the fenthion and the spirotetramat is obtained.

In yet another aspect, there is provided the use of the pesticidal composition for controlling plant pests.

Further, the plant pest includes at least one of thrips, psyllids, whiteflies and aphids, and optionally thrips.

In yet another aspect, a method for controlling plant diseases and insect pests with the pesticide composition is provided, wherein the pesticide composition is prepared into a dosage form and is spread in a farmland.

Advantageous effects

(1) The composition is suitable for controlling pests such as green beans, mangoes, melons and the like, such as thrips, aphids and psyllids, and is especially suitable for controlling mangoes thrips. The two pesticide active ingredients have synergistic effect, and can reduce the total application amount, thereby being more efficient and environment-friendly.

(2) The invention adopts the suspending agent type preferentially, and the particles of the phoxim, the spirotetramat and the mineral oil are dispersed in water, thus having the following advantages: the flash point is high, the combustion and explosion are avoided, and the production, storage and use are safe; the dust is less, the environmental pollution is less, and the environment is safe for producers and users; the water is used as a matrix, so that the resource is rich, the product cost is low, and the packaging is easy; after the preparation is sprayed, fine particles are distributed on the surface of crops, so that the pesticide effect is good; after the adhesive is added, the surface tension of the liquid medicine can be reduced, the adhesiveness of the liquid medicine can be improved, the wetting expansibility and the rain wash resistance of the liquid medicine can be improved, and the utilization rate of the liquid medicine can be improved.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention. Throughout the specification and claims, unless explicitly stated otherwise, the term "comprise" or variations thereof such as "comprises" or "comprising", etc. will be understood to include the stated element or component without excluding other elements or components.

In addition, numerous specific details are set forth in the following description in order to provide a better illustration of the invention. It will be understood by those skilled in the art that the present invention may be practiced without some of these specific details. In some embodiments, materials, elements, methods, means, etc. well known to those skilled in the art are not described in detail in order to highlight the gist of the present invention.

The phoxim and spirotetramat of the invention can be obtained by a commercial method.

EXAMPLE 1 35% Phosphaerofos-spirotetramat suspoemulsion

The composition is as follows:

example 2 60% phoxim spirotetramat suspoemulsion consists of:

EXAMPLE 3 50% Phosphaerofos spirotetramat suspoemulsion

The composition is as follows:

EXAMPLE 4 40% Phosphaphos-spirotetramat suspoemulsion

The composition is as follows:

example 5 45% Phosphaerofos spirotetramat suspoemulsion

The composition is as follows:

the preparation method of the suspoemulsion comprises the following steps:

uniformly mixing the phoxim, the spirotetramat and the auxiliary agent according to the corresponding proportion, and continuously sanding by a sand mill to ensure that the D90 particle size is below 5 mu m, thus obtaining the pesticide suspoemulsion containing the phoxim and the spirotetramat.

Test example 1

In order to know the exact toxicity of the compound of the fenthion and the spirotetramat on thrips, the proportion of the compound is screened through indoor toxicity measurement, so that the co-toxicity coefficient (CTC) of the compound of the two medicaments according to a certain proportion is clear, CTC is smaller than 80 and is antagonistic, CTC is larger than or equal to 80 and smaller than or equal to 120 and is additive, and CTC is larger than 120 and is synergistic.

The specific test method comprises the following steps: the mother liquor of each mixed agent is diluted into 5 series of concentrations respectively and is placed in a beaker for standby. Placing 20 thrips and cleaned mango tender leaves in a breathable transparent box, uniformly spraying liquid medicine in the box and on plants, and feeding at 26 ℃. Each treatment was repeated 5 times while a water spray blank was set, and the number of dead insects was checked after 24 hours. Calculating mortality and correcting mortality, solving a virulence regression equation and calculating LC ₅₀ Values. If the control mortality rate is greater than 10%, it is considered an ineffective test. The calculation formula is as follows:

mortality (%) = (number of live insects before drug-number of live insects after drug)/number of live insects before drug x 100

Corrected mortality (%) = (treatment group mortality-control group mortality)/(1-control group mortality) ×100

Converting the corrected mortality of the pests into a mechanical value (y), converting the treatment concentration (μg/ml) into a logarithmic value (x), deriving a virulence regression equation by a least squares method, and thereby calculating LC for each agent ₅₀ Values. Calculating the co-toxicity coefficient according to Sun Yun Pei formula

CTC calculation formula (standard agent of phosphorus bisulfide, toxicity index 100):

LC of spirotetramat Toxicity Index (TI) =fenthion ₅₀ LC of spirotetramat ₅₀ ×100

LC of actual virulence index (ATI) =fenthion of M ₅₀ LC of/M ₅₀ ×100

Theoretical virulence index (TTI) =ti×p of fenthion for M _{Phosphorus sesquialter} TI x P of +spirotetramat _{Spirotetramat}

TTI/M TTI x 100 for co-toxicity coefficient (CTC) =M

Wherein: m is the mixture of the phoxim and the spirotetramat in different proportions

P _{Spirotetramat} Is the proportion of the spirotetramat in the mixture

P _{Phosphorus sesquialter} Is the proportion of the phosphorus-sulfur-doubling compound in the mixture

Test pest: mango thrips

The test agents are all provided by the Buddha's Yinghui crop science Co. And (3) test design: and a preliminary test is carried out to determine the effective lethal concentration range of the mixed agent of the fenthion and the spirotetramat in different proportions. The experimental results are shown in table 1 below:

table 1 determination of indoor toxicity of various formulations of phoxim and spirotetramat to mango thrips

Proportioning of	Toxicity regression equation	Correlation coefficient	LC ₅₀ (mg/l)	Co-toxicity coefficient (CTC)
					Phosphorus sesquialter (A)	Y＝0.2938+1.7919x	0.9902	422.99	—
Spirotetramat (B)	Y＝2.0410+1.9753x	0.9962	31.48	—
					A:B(6:1)	Y＝1.1958+1.9105x	0.9877	97.99	155.45
A:B(5:1)	Y＝1.4616+1.8748x	0.9863	77.15	178.42
					A:B(4:1)	Y＝1.6920+1.8651x	0.9855	59.37	204.29
A:B(3:1)	Y＝1.6536+1.7644x	0.9914	78.82	130.60
					A:B(2:1)	Y＝1.7578+1.8262x	0.9820	59.61	137.89

As can be seen from table 1, the fenthion and the spirotetramat show a synergistic effect on the control of mango thrips in the range of 6:1-2:1, wherein when the ratio of the fenthion to the spirotetramat to the mango thrips is 4:1, the co-toxicity coefficient of the control of the mango thrips is above 200, and the synergistic effect is more remarkable.

Test example 2

Field efficacy test

Experimental treatment: the experiment designs two medicament dosages according to different components, wherein the medicament dosages are the mass sum of the effective components of the phoxim and the spirotetramat. The control agent is 50% of a suspending agent of phosphorus sulfate and 22.4% of a suspending agent of spirotetramat and a blank clear water test.

The test method comprises the following steps: each cell area is 66.7m ² Repeating for 3 times; the investigation and drug effect method after the drug application is that 5 points are randomly sampled in a test treatment area, and the insect population investigation is carried out according to the relevant national field test standard, so as to calculate the control effect. The test results are shown in tables 2 and 3 below:

table 2 field efficacy test of different drug treatments on mango thrips

Table 3 field efficacy test of different drug treatments on thrips carob

As shown in tables 2 and 3, the field efficacy test results show that after the combination of the fenthion and the spirotetramat, mango and bean thrips can be effectively prevented and treated, the composition provided by the invention has obvious synergistic effect, and the prevention effect is higher than that of a single fenthion agent and a single spirotetramat agent, so that the pesticide composition provided by the invention can be used for preventing and treating thrips well, reducing the dosage, reducing the cost, delaying the generation of drug resistance of thrips and reducing the pollution to the environment. In conclusion, the pesticide composition is worthy of popularization and application in production.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. The pesticide composition is characterized in that the active ingredients comprise the phoxim and the spirotetramat, and the weight ratio of the phoxim to the spirotetramat is 6:1-2:1.

2. The pesticide composition as set forth in claim 1, wherein the weight ratio of the fenthion to the spirotetramat is 6:1 to 4:1.

3. The pesticide composition as set forth in claim 1, wherein the weight ratio of the fenthion to the spirotetramat is 5:1 to 4:1.

4. A pesticide composition as set forth in claim 1 wherein the weight ratio of the fenthion to the spirotetramat is 6:1, 5:1, 4:1, 3:1 or 2:1.

5. The pesticide composition as set forth in claim 1, wherein the content of the active ingredient is 10% to 80% of the total amount of the composition, and the balance is the adjuvant.

6. The pesticide composition as set forth in claim 1, wherein the content of the active ingredient is 35% -60% of the total amount of the composition, and the balance is the adjuvant.

7. The pesticide composition as set forth in claim 1, wherein the content of the active ingredient is 50% -60% of the total amount of the composition, and the balance is the adjuvant.

8. A pesticide composition as set forth in claim 1, characterized in that the active ingredient is present in an amount of 50% of the total composition, the balance being adjuvants.

9. The pesticidal composition according to claim 5, wherein the adjuvant is any one or more of a dispersant, an emulsifier, an antifreezing agent, a thickener, a preservative, an antifoaming agent, a solvent, a wetting agent, a disintegrant and a filler.

10. A pesticide composition as set forth in claim 9 wherein said solvent is water.

11. A pesticide composition as set forth in any one of claims 5 to 10, wherein said pesticide composition is in the form of a suspension, an aqueous emulsion, a microemulsion, an emulsifiable concentrate, a wettable powder, a microcapsule suspension, a water dispersible granule, a soluble powder, a soluble granule or a suspoemulsion.

12. A pesticidal composition according to any of claims 5 to 10, in the form of a suspoemulsion, and the adjuvants comprise a medium oil, a wetting dispersant, an emulsifier, a thickener, an anti-freeze agent, a stabilizer, an antifoaming agent, a preservative and water.

13. The pesticide composition as set forth in claim 12, wherein the auxiliary agent comprises the following components in mass percent: 0.5-20% of medium oil, 3-15% of wetting dispersant, 1-10% of emulsifier, 0.1-3% of thickener, 1-5% of antifreeze agent, 0.1-10% of stabilizer, 0.1-2% of defoamer, 0.1-1.5% of preservative and water which are added to 100%.

14. The pesticide composition as set forth in claim 12, wherein the auxiliary agent comprises the following components in mass percent: 1-13% of medium oil, 8-15% of wetting dispersant, 3-10% of emulsifier, 0.1-0.2% of thickener, 4-5% of antifreeze agent, 2-5% of stabilizer, 0.1-0.2% of defoamer, 0.1-1.5% of preservative and water which are added to 100%.

15. A pesticide composition as set forth in claim 13 wherein said medium oil is selected from vegetable oil, mineral oil and/or paraffinic oil.

16. A pesticide composition as set forth in claim 13 wherein said wetting dispersant is selected from one or more of sodium dodecylbenzene sulfonate, nekal, dodecyl polyoxyethylene ether phosphate, nonylphenol polyoxyethylene ether, potassium oleate, sodium lignin sulfonate, sodium laureth sulfate and alkyl naphthalene formaldehyde condensate sulfonate.

17. The pesticide composition of claim 13, wherein the emulsifier is selected from one or more of a high molecular EO-PO block copolymer, a NP series of nonylphenol polyoxyethylene ether, alkylphenol polyoxyethylene polyether and its sulfate or phosphate, an AEO series of fatty alcohol polyoxyethylene ether, a nonylphenol polyoxyethylene ether phosphate, an alkylphenol polyoxyethylene ether formaldehyde condensate sulfate phosphate, a styrylphenol formaldehyde resin polyoxyethylene ether phosphate, a styrylphenol polyoxyethylene polyoxypropylene ether, a span series, and a tween series.

18. A pesticide composition as set forth in claim 13 wherein said thickener is selected from one or more of xanthan gum, acacia, carboxymethylcellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, methylcellulose and polyvinyl alcohol.

19. A pesticide composition as set forth in claim 13 wherein said antifreeze agent is selected from one or more of ethylene glycol, glycerol, propylene glycol, polyethylene glycol and sorbitol or urea.

20. A pesticide composition as set forth in claim 13 wherein said stabilizer is selected from one or more of epoxidized soybean oil, linseed oil, citric acid and sodium sorbate.

21. A pesticide composition as set forth in claim 13 wherein said defoamer is selected from one or more of silicone defoamers, C8-C10 fatty alcohol compounds and II-ethyl alcohol.

22. A pesticide composition as set forth in claim 13 wherein said preservative is selected from one or more of sodium benzoate, benzoic acid and sodium diacetate.

23. A process for preparing a pesticidal composition as claimed in any one of claims 1 to 22, characterized in that the phosphorus sesquioxide, spirotetramat and auxiliary agent are mixed in the corresponding proportions and continuously sanded by a sand mill to give D ₉₀ The grain diameter is below 5 mu m, and the pesticide suspending emulsion containing the phoxim-spirotetramat is obtained.

24. Use of a pesticidal composition according to any one of claims 1 to 22 for controlling plant pests.

25. The use according to claim 24, wherein said plant-pest pests include at least one of thrips, psyllids, whiteflies and aphids.

26. The use of claim 24, wherein the plant pest is thrips.

27. A method of controlling plant diseases and insect pests with the pesticidal composition according to any one of claims 1 to 22, wherein the pesticidal composition is prepared in a form of a dosage form for application to a farmland.