CN114917299A - Traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and preparation method thereof - Google Patents

Traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and preparation method thereof Download PDF

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CN114917299A
CN114917299A CN202210516500.5A CN202210516500A CN114917299A CN 114917299 A CN114917299 A CN 114917299A CN 202210516500 A CN202210516500 A CN 202210516500A CN 114917299 A CN114917299 A CN 114917299A
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preparation
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chinese medicine
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accommodation
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CN114917299B (en
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韩治华
杨淑焕
安胜
吴沂旎
冀璐
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Shaanxi Traditional Chinese Medicine Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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Abstract

The invention relates to a traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and a preparation method thereof, and also discloses a using method thereof, wherein the traditional Chinese medicine eye applying preparation comprises the following components: radix rehmanniae, folium Mori, radix Ophiopogonis, radix Angelicae sinensis, rhizoma Acori Graminei, cortex et radix Polygalae and herba Taraxaci; the components in parts by mass are as follows: 6-12 parts of radix rehmanniae, 6-12 parts of mulberry leaves, 6-12 parts of radix ophiopogonis, 4-10 parts of angelica sinensis, 4-10 parts of rhizoma acori graminei, 4-10 parts of polygala tenuifolia and 4-10 parts of dandelion; the angelica is processed, and the polygala is processed.

Description

Traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and preparation method thereof
Technical Field
The invention belongs to the technical field of biological medicines, and particularly relates to a traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and a preparation method thereof.
Background
Juvenile myopia has become a common disease in the global scope, and the axial length of the eye of the accommodation myopia is normal or in the accommodation range, so that the vision can be recovered to a certain degree through related intervention treatment. Modern medicine believes that accommodative myopia occurs as a result of ciliary muscle spasms resulting from overuse of the eye. The traditional Chinese medicine considers that the accommodation myopia belongs to the category of 'capable of approaching and removing short-distance symptoms', and is also called as 'a lot of eyes'. The disease prevention is the root of the Chinese medicine 'preventive treatment' before the disease is maintained firstly, and plays an important guiding role in the prevention and treatment of the adolescent accommodation myopia. Modern medicine cannot radically cure myopia, so the adoption of prevention and treatment measures is particularly important. At present, the treatment of the traditional Chinese medicine mainly adopts acupuncture point massage, acupuncture and moxibustion around eyes and ear acupuncture points, but is easily limited by time, economy and technology, time and labor are consumed, and a child patient cannot be completely matched. The traditional Chinese medicine eye application treatment is a simple, convenient and fast intervention means which has no side effect and is easily accepted by teenagers, so as to reduce the incidence of myopia and complications thereof.
Chinese patent 'a traditional Chinese medicine eye fumigating preparation and a preparation method and application thereof' (application date: 2021.01.13; application number: 202110044456.8; application publication number: CN 112717001A) discloses a traditional Chinese medicine eye fumigating preparation and a preparation method and application thereof, although the invention has obvious curative effect on ocular surface diseases including xerophthalmia, meibomian gland dysfunction, keratitis and conjunctivitis, the scheme has unknown curative effect on adolescent accommodation myopia, and the traditional Chinese medicine formula is strict in proportion and complex in dispensing procedure, thus resulting in low safety.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides the traditional Chinese medicine eye applying preparation for treating the juvenile accommodation myopia and the preparation method and the use method thereof, so that the eye discomfort caused by the juvenile accommodation myopia can be effectively relieved, the stability of the tear film is ensured, the defects of time and labor consumption of other traditional Chinese medicine treatment methods are avoided, and the traditional Chinese medicine eye applying preparation has higher safety.
In order to achieve the above purpose, the invention adopts the technical scheme that: a traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia comprises the following components: radix rehmanniae, folium Mori, radix Ophiopogonis, radix Angelicae sinensis, rhizoma Acori Graminei, cortex et radix Polygalae and herba Taraxaci;
the components in parts by mass are as follows: 6-12 parts of dried rehmannia root, 6-12 parts of mulberry leaf, 6-12 parts of dwarf lilyturf tuber, 4-10 parts of Chinese angelica, 4-10 parts of grassleaf sweelflag rhizome, 4-10 parts of thinleaf milkwort root-bark and 4-10 parts of dandelion;
processing the angelica; processing cortex et radix Polygalae.
Further, 0.24-0.6 part by mass of liquorice is also included; the radix Glycyrrhizae can be used for processing cortex et radix Polygalae.
A preparation method of a traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia comprises the steps of processing 60-120 g of radix rehmanniae, 60-120 g of folium mori, 60-120 g of radix ophiopogonis, 40-100 g of wine-processed angelica sinensis, 40-100 g of rhizoma acori graminei and 40-100 g of prepared polygala tenuifolia and dandelion, mixing and crushing into coarse powder, uniformly stirring, filling the coarse powder into non-woven fabric bags of 7cm x 9cm in size, sewing and subpackaging, and filling 10g of the coarse powder into each bag.
Further, a preparation method of the traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia comprises the following steps:
(1) selecting 60-120 g of radix rehmanniae, 60-120 g of mulberry leaves, 60-120 g of radix ophiopogonis, 40-100 g of rhizoma acori graminei and 40-100 g of dandelion, removing impurities, cleaning with clear water, and moistening thoroughly;
(2) taking the angelica slices, adding yellow wine, stirring uniformly, slightly stewing, frying to deep yellow with slow fire after the wine is completely absorbed, taking out, and cooling to obtain 40-100 g of wine-treated angelica;
(3) the weight ratio of polygala root: taking liquorice at a ratio of 50:3, adding a proper amount of water to decoct, removing residues, adding clean polygala tenuifolia, decocting with slow fire until the decoction is completely absorbed, taking out, and drying to prepare 40-100 g of polygala tenuifolia;
(4) mixing the seven medicinal materials, placing in a ventilation chamber, and pulverizing into coarse powder with a full-automatic Chinese medicinal pulverizer;
(5) mixing the coarse powders uniformly to prepare mixed powder;
(6) and filling the mixed powder into non-woven fabric bags with the size of 7cm x 9cm, and sewing into finished products, wherein each bag contains 10g of the mixed powder, so that the traditional Chinese medicine eye applying preparation is obtained.
Further, the slow fire in the step (2) is 80-120 ℃; the Chinese angelica in the finished wine is prepared from the following Chinese angelica in percentage by mass: the yellow wine is prepared in a ratio of 10: 1.
Further, the proper amount of water is added in the step (3) to just submerge the medicine; the slow fire in the step (3) is 80-120 ℃.
Further, screening by using a screen with the mesh number of 24 meshes in the step (4); the drying conditions were: drying temperature: drying at 60-70 ℃ for: 3-5 h.
A method for using a Chinese medicinal eye-applying preparation for treating adolescent accommodation myopia comprises soaking a Chinese medicinal eye-applying bag in cold water for 10min, heating, boiling water for 5min, turning off fire, cooling, taking out the bag in water, drying, and directly applying to eyes until the bag is cooled.
The invention has the technical effects that: (1) the traditional Chinese medicine eye compress preparation prepared by the invention is prepared by adding and subtracting a classic prescription Zengye decoction (radix rehmanniae and radix ophiopogonis), the original prescription adds the functions of nourishing liver, enriching blood, regulating qi and inducing resuscitation of mulberry leaves, angelica sinensis, rhizoma acori graminei, polygala tenuifolia and dandelion, the prescription has the functions of clearing heat and promoting the production of body fluid, nourishing liver and enriching blood, calming the heart and tranquilizing the mind, regulating qi and inducing resuscitation, and clearing liver and improving eyesight, is suitable for the diseases of congenital endowment deficiency or chronic sight blood injury, liver blood consumption or yin and yang imbalance, yang deficiency and light failure to cross distant, and is suitable for eye diseases such as blurred vision, eye fatigue, dry and acerbity pain, eye swelling and pain and discomfort and the like. Can effectively relieve the discomfort of eyes caused by the adolescent accommodation myopia.
(2) The traditional Chinese medicine eye compress preparation prepared by the invention has the effects of diminishing inflammation, sterilizing, regulating immunity, resisting aging and the like, and can stimulate acupuncture points around eyes and relax muscles around eyes, thereby quickly relieving uncomfortable symptoms such as blurred vision, dry eyes, fatigue, swelling pain of eye sockets and the like.
(3) The traditional Chinese medicine eye compress preparation prepared by the invention can avoid frequent eye dropping to wash and dilute tears, ensure the stability of tear film, avoid the defects of time and labor consumption of other traditional Chinese medicine treatment methods, and is easy to accept by children patients and has higher safety.
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FIG. 1 is a flow chart of one embodiment of the present invention;
fig. 2 is a flow chart of a preferred embodiment of the present invention.
Detailed Description
The technical solutions of the embodiments of the present invention will be described clearly and completely below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without any inventive step, are within the scope of the present invention.
The invention discloses a traditional Chinese medicine eye compress preparation for treating adolescent accommodation myopia and a preparation method thereof, which is prepared by mixing and crushing rehmannia root, mulberry leaf, dwarf lilyturf tuber, wine-treated Chinese angelica, grassleaf sweelflag rhizome, prepared polygala root and dandelion into coarse powder, uniformly stirring, filling the coarse powder into non-woven fabric bags with the size of 7cm x 9cm, sewing and subpackaging, and filling about 10g of the coarse powder into each bag. By adopting the technical scheme of the invention, the discomfort of eyes caused by the adolescent accommodation myopia can be effectively treated, and the myopia of children and adolescents can be effectively prevented and controlled.
Specifically, the traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia comprises the following components: radix rehmanniae, folium Mori, radix Ophiopogonis, radix Angelicae sinensis, rhizoma Acori Graminei, cortex et radix Polygalae and herba Taraxaci.
The components in parts by mass are as follows: 6-12 parts of dried rehmannia root, 6-12 parts of mulberry leaf, 6-12 parts of dwarf lilyturf tuber, 4-10 parts of Chinese angelica, 4-10 parts of grassleaf sweelflag rhizome, 4-10 parts of thinleaf milkwort root-bark and 4-10 parts of dandelion;
processing the angelica; processing cortex et radix Polygalae.
A preparation method of a traditional Chinese medicine eye compress preparation for treating adolescent accommodation myopia comprises the steps of processing 60-120 g of radix rehmanniae, 60-120 g of folium mori, 60-120 g of radix ophiopogonis, 40-100 g of wine angelica, 40-100 g of rhizoma acori graminei and 40-100 g of prepared polygala tenuifolia and dandelion, mixing and crushing into coarse powder, uniformly stirring, filling the coarse powder into non-woven fabric bags of 7cm x 9cm in size, sewing and subpackaging, and filling 10g of the coarse powder into each bag.
Preferably, the preparation method of the traditional Chinese medicine eye applying preparation for treating the adolescent accommodation myopia comprises the following steps:
(2) selecting 60-120 g of radix rehmanniae, 60-120 g of mulberry leaves, 60-120 g of radix ophiopogonis, 40-100 g of rhizoma acori graminei and 40-100 g of dandelion, removing impurities, cleaning with clear water, and moistening thoroughly;
(2) taking the angelica slices, adding yellow wine, stirring uniformly, slightly stewing, frying with slow fire (the temperature is 80-120 ℃, the flame is small and light) to deep yellow after the wine is completely absorbed, taking out, and cooling to obtain wine angelica (40-100 g) (according to the mass ratio of the angelica to the yellow wine is 10: 1).
(3) Taking liquorice (polygala tenuifolia: liquorice is 50:3 in mass ratio), adding a proper amount of water (just submerging the medicines), decocting the liquorice into soup, removing residues, adding neat polygala tenuifolia, decocting the mixture with slow fire (the temperature is 80-120 ℃, the flame is small, the mixture floats and is light, and the soup slowly boils) until the soup is absorbed completely, taking out the mixture, and drying the mixture to prepare polygala tenuifolia (40-100 g).
(4) Mixing the seven medicinal materials, placing the mixture in a ventilation chamber, and crushing the mixture into coarse powder (the mesh number of a screen is 24 meshes, the drying condition is that the drying temperature is 60-70 ℃ and the drying time is 3-5 hours) by using a full-automatic traditional Chinese medicine crusher.
(5) Mixing the above coarse powders, and making into mixed powder.
(6) The mixed powder is packed into non-woven fabric bags with the size of 7cm x 9cm and sewed into finished products (about 10g per bag). Thus obtaining the traditional Chinese medicine eye compress preparation.
Example (b):
the invention relates to a traditional Chinese medicine eye compress preparation for treating adolescent accommodation myopia, which is prepared by mixing medicine compositions in proportion, and comprises the following components in parts by weight: 6-12 g of radix rehmanniae, 6-12 g of folium mori, 6-12 g of radix ophiopogonis, (processed) 4-10 g of angelica sinensis, 4-10 g of rhizoma acori graminei, (processed) 4-10 g of polygala tenuifolia and 4-10 g of dandelion. Wherein, the dried rehmannia root, the dwarf lilyturf tuber, the mulberry leaf and the dandelion have the efficacies of nourishing yin, clearing heat, removing heat from the liver and improving eyesight, the dried rehmannia root has the efficacies of clearing heat, promoting fluid, cooling blood and stopping bleeding, the dwarf lilyturf tuber has the efficacies of nourishing yin, moistening lung, benefiting stomach, promoting fluid, clearing heart and relieving restlessness, the mulberry leaf has the efficacies of dispelling wind and heat, clearing lung, moistening dryness, clearing liver and improving eyesight, the grassleaf sweelflag rhizome and the polygala root (processed) have the efficacies of calming heart, soothing nerves, inducing resuscitation and refreshing mind, and the angelica has the efficacies of enriching blood, activating blood and resisting aging. Modern pharmacological studies show that the extracts or effective components of the medicines such as the rehmannia root, the mulberry leaf, the dwarf lilyturf tuber and the like have the effects of expanding blood vessels, improving local microcirculation and promoting tear secretion to achieve the effects of supplementing liquid and improving eyesight, and the grassleaf sweelflag rhizome and the processed thinleaf milkwort root-bark also have the effects of resisting inflammation, resisting oxidation, regulating immunity and the like. Meanwhile, the radix ophiopogonis has the effects of removing free radicals and relieving eye muscle fatigue, and the folium mori has the anti-fatigue effect.
Various medicines in the traditional Chinese medicine eye compress preparation have the effects of diminishing inflammation, sterilizing, regulating immunity, resisting aging and the like. The traditional Chinese medicine can stimulate acupuncture points around the eyes and relax muscles around the eyes when being applied to the eyes, so that uncomfortable symptoms such as blurred vision, dry eyes, fatigue, orbital swelling pain and the like can be quickly relieved; can also avoid the washing and dilution of tears by frequent eye dropping and ensure the stability of the tear film. Finally, the eye compress avoids the defects of time and labor consumption of other traditional Chinese medicine treatment methods, and meanwhile, the children patients are easy to accept, and the eye compress medicine has higher safety.
Besides the advantages of the traditional Chinese medicine eye compress, the traditional Chinese medicine eye compress preparation can be flexibly applied to portable or household operation, so that the eye compress preparation can be carried about or used at home, the dependence of patients on hospitals is eliminated, and the eye compress preparation can be really used anytime and anywhere, so that the purposes of the convenience of eye drops, more sufficient absorption than the eye drops and more lasting effect are realized. Has the advantages of economy, convenience, good curative effect, small side effect and the like, and is suitable for popularization.
The traditional Chinese medicine eye compress preparation of the invention is used for treating adolescent accommodation myopia and has the following curative effect analysis:
in 2020, 346 children patients who have undergone diagnosis and diagnosis of the accommodative myopia in Shaanxi province in TCM hospitals are statistical subjects. Patients were randomly divided into a group of eye application with rational eyes + outdoor activity + eye application with hot towel (hereinafter referred to as a control group) and a group of eye application with rational eyes + outdoor activity + hot towel + eye application with Chinese medicine of the present invention (hereinafter referred to as a treatment group). Among 346 patients, 208 men and 138 women; the age is 5-15 years, and the average age is 8.7 years; the treatment group was randomly divided into 259 cases and the control group was divided into 87 cases. The disease duration of the patient is 1-6 months, and the average disease duration is 2.3 months; all patients had normal near vision with an average distance vision of 0.35. There was no significant difference in the general case of the two groups of patients compared (P > 0.05).
The treatment method comprises the following steps: the reasonable eye using, outdoor activity and hot towel eye applying treatment method comprises controlling eye using posture of children patients, increasing outdoor activity (2 h/day), and applying eye topically. The eye applying method comprises soaking the medicated bag in cold water for 10min, heating, boiling for 5min, turning off fire, cooling, taking out the medicated bag, and directly applying onto eyes until the medicated bag is cooled. Every 10 times is a treatment course, and the next treatment is carried out 1 week after the treatment is finished, and 4 continuous treatment courses are carried out. The myopia curative effect judgment standard is drawn up according to the clinical research guiding principle of the new traditional Chinese medicine, and the effect is obvious: the clinical symptoms are basically eliminated or the main symptoms are basically eliminated, the distance vision is improved by more than 3 lines, or the refraction of the inspection optometry myopia after mydriasis is obviously reduced compared with that before treatment; the method has the following advantages: the clinical symptoms are obviously improved, the distance vision is improved by 2 lines, or the refractive power of the eye test near vision after mydriasis is reduced compared with that before treatment; and (4) invalidation: the clinical symptoms are improved to different degrees or not improved, the distance vision is improved by less than 1 line, or the myopia diopter of the examination vision after mydriasis is reduced. The total effective is significant effect plus effective. The statistical method comprises the following steps: data were counted using the χ 2 test, expressed as rate (%), (P <0.05 with significant differences).
TABLE 1 statistics of therapeutic effects after treatment of accommodative myopia
Group of N (number of cases) Show effect Is effective Nullification The total effective rate%
Treatment group 259 121(46.72) 104(40.15) 34(13.13) 225(86.87)
Control group 87 32(36.78) 35(40.23) 20(22.99) 67(77.01)
t 4.8080
P 0.0283
The curative effect is shown in the following table 1, the effective rate of eye application of the traditional Chinese medicine is 86.87%, and the difference is obvious by chi fang test of a far higher control group.
TABLE 2 comparison of vision and diopter before and after treatment
Figure BDA0003639862400000091
Figure BDA0003639862400000092
The vision of the treatment group and the control group is improved compared with that before the treatment, the vision of the treatment group is improved obviously compared with that of the control group after the treatment, and the comparison difference of the two groups has statistical significance (P is less than 0.05); the diopter of the treatment group and the control group is reduced compared with that of the control group before treatment, the diopter of the treatment group is reduced compared with that of the control group after treatment, and the comparison difference of the two groups has statistical significance (P is less than 0.05);
the reasonable use of eyes and outdoor activities combined with the eye application of the traditional Chinese medicine eye application preparation can improve the clinical symptoms of asthenopia of children patients, and further control the development of myopia.
2 cases of the traditional Chinese medicine eye compress preparation for treating the accommodation myopia are analyzed:
case 1
Zhang Xin, female, 5 years old, Xian city, Token Lin district, and the doctor visits our hospital on 15/01/2020 mainly by "find children with binocular vision degraded by more than 2 months". Parents find that children patients like squinting in sight before 2 months, frequently twinkling eyes, rubbing eyes and no red eyes, and eye drops such as sodium hyaluronate eye drops and Runjie are used before and after local hospitals, so that frequent twinkling symptoms can be improved, but the children patients still feel long-distance blurred vision and the symptoms are aggravated. The doctor visits the clinic at our hospital. After onset, the patient has clear mind, good spirit, normal stomach, and good sleep, and is convenient for adjustment without obvious weight loss. The disease is marked as follows: both eyes are blurred and blink frequently, and they like rubbing and closing eyes. A pale-red tongue with thin and white coating and a thready and rapid pulse. Parents are both high myopia with eyes, and children patients have a history of using the mobile phone for a long time.
Special examination: and (3) eyesight: OD: 0.3, OS: 0.3-, intraocular pressure: OD: 11mmHg, OS: 14mmHg, binocular conjunctival congestion, narrow lacrimal river, clear cornea, deep in the anterior chamber, round pupil, diameter about 3mm, sensitive to light reflection, clear lens, fundus: the optic disk is red, the macula is inversely visible, and the retina is flat.
Auxiliary inspection: before mydriasis: and (3) for the right eye: -0.75DS, left eye: 1.00DS, atropine mydriatic refraction: and (3) for the right eye: degree, left eye: -0.25DS → 1.0.
And (3) diagnosis: binocular accommodative myopia.
The treatment process comprises the following steps: the children are informed to reasonably use the eyes, the using time of electronic products is reduced, the patients can pay attention to diet sanitation and control eye rubbing by proper outdoor activities, and meanwhile, the eyes are locally matched with traditional Chinese medicines for eye application treatment. After 4 treatment courses, the children are more clear in vision, blink frequently, and like rubbing eyes and closing eyes are improved obviously.
The children patients have the following vision for the second visit after treatment: OD: 0.9, OS: 0.7-, mydriatic binocular diopters as follows: and (3) for the right eye: degree, left eye: 0.25DS → 1.0, the clinical curative effect is good.
Case 2
Wang, man, 4 years old, Amaran, Xian, who was first diagnosed in my family on 7 months 03 days in 2020 as the chief complaint of "finding binocular vision low for about 3 months" in physical examination. Parents unconsciously find that the eyes of children are lower than those of children of the same age before 3 months, and the children are free from discomfort such as red eyes, ophthalmalgia and the like, and then go to the hospital for the children refractive outpatient service. After onset, the patient has clear mind, good spirit, normal stomach, and good sleep, and is convenient for adjustment without obvious weight loss. The disease is marked as follows: the children patients have impaired vision in both eyes, prefer rubbing eyes, have pale red tongue with thin coating and wiry pulse. Family history: the mother and the sister of the child have high myopia.
Special examination: intraocular pressure: eyes of 10mmHg, naked eye vision: OD: 0.25, OS: 0.3, mild redness of conjunctiva of both eyes, narrow lacrimal river, transparent cornea, deep in the anterior chamber, round pupil, diameter of about 3mm, sensitivity to light reflection, transparent lens, fundus: the optic disk is red, the macula is inversely visible, and the retina is flat.
Auxiliary inspection: before mydriasis: and (3) for the right eye: 0.75DS, left eye: 0.50DS, atropine mydriatic refraction: and (3) for the right eye: -0.25DS → 0.8, left eye: there are no degrees.
And (3) diagnosis: binocular accommodation myopia.
The treatment process comprises the following steps: the children are informed to reasonably use the eyes, the using time of electronic products is reduced, the patients can pay attention to diet sanitation and control eye rubbing by proper outdoor activities, and meanwhile, the eyes are locally matched with traditional Chinese medicines for eye application treatment. After 4 treatment courses, the children who suffer from the disease are willing to knead eyes better obviously.
The children patients have the following vision for the second visit after treatment: OD: 0.8, OS: 0.7, mydriatic binocular diopters are as follows: two eyes: no degree, good clinical curative effect.
Case analysis: two cases of children in the group have symptoms of binocular accommodation myopia, double eyes are fond of rubbing eyes, family history of high myopia and the like, although reasonable eye use and outdoor movement are used for alleviating the symptoms, the effect is not obvious, as the ages of the children are increased, academic pressure is increased, close-range eye use is increased, clinical curative effect of conventional protection treatment is poor, and myopia develops early. Modern medicine does not have a safe and reliable method for preventing and controlling the occurrence of the accommodative myopia. The eye application of the traditional Chinese medicine can help children patients to delay the occurrence of myopia, is safe and reliable, has lasting symptom relief, and embodies the advantages of clinical treatment.
The traditional Chinese medicine eye applying preparation is prepared aiming at the accommodation myopia, the whole formula mainly takes the effects of nourishing yin, clearing heat, inducing resuscitation and improving eyesight, and the problem that children patients with the myopia have no medicine can be treated is successfully solved. More importantly, the early occurrence of the accommodation myopia is avoided, and the traditional Chinese medicine is applied to the eyes to combine with the correct myopia prevention and control measures, so that the development of the infant patient to true myopia can be delayed. And for young patients, the traditional Chinese medicine eye compress has no discomfort, simple operation, easier cooperation and more ideal curative effect.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered as the technical solutions and the inventive concepts of the present invention within the technical scope of the present invention.

Claims (8)

1. A traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia is characterized by comprising the following components: radix rehmanniae, folium Mori, radix Ophiopogonis, radix Angelicae sinensis, rhizoma Acori Graminei, cortex et radix Polygalae and herba Taraxaci;
the components in parts by mass are as follows: 6-12 parts of dried rehmannia root, 6-12 parts of mulberry leaf, 6-12 parts of dwarf lilyturf tuber, 4-10 parts of Chinese angelica, 4-10 parts of grassleaf sweelflag rhizome, 4-10 parts of thinleaf milkwort root-bark and 4-10 parts of dandelion;
processing the angelica; processing cortex et radix Polygalae.
2. The traditional Chinese medicine eye compress preparation for treating adolescent accommodation myopia according to claim 1, which is characterized in that: 0.24-0.6 parts by mass of liquorice is also included; the radix Glycyrrhizae can be used for processing cortex et radix Polygalae.
3. A preparation method of a traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia is characterized in that: 60-120 g of radix rehmanniae, 60-120 g of mulberry leaves, 60-120 g of radix ophiopogonis, 40-100 g of wine-treated angelica, 40-100 g of rhizoma acori graminei and 40-100 g of prepared polygala tenuifolia and dandelion which are prepared by processing liquorice decoction are mixed and crushed into coarse powder, the coarse powder is uniformly stirred and filled into non-woven bags of 7cm x 9cm in size for sewing and subpackaging, and 10g of the coarse powder is filled into each bag.
4. The preparation method of the traditional Chinese medicine eye compress preparation for treating juvenile accommodation myopia according to claim 3, characterized by comprising the following steps:
(1) selecting 60-120 g of radix rehmanniae, 60-120 g of mulberry leaves, 60-120 g of radix ophiopogonis, 40-100 g of rhizoma acori graminei and 40-100 g of dandelion, removing impurities, cleaning with clear water, and moistening thoroughly;
(2) taking the angelica slices, adding yellow wine, stirring uniformly, slightly stewing, frying to deep yellow with slow fire after the wine is completely absorbed, taking out, and cooling to obtain 40-100 g of wine-treated angelica;
(3) the weight ratio of polygala root: taking liquorice, adding a proper amount of water to decoct, removing slag, adding clean polygala tenuifolia, decocting with slow fire until the decoction is completely absorbed, taking out, and drying to prepare 40-100 g of polygala tenuifolia;
(4) mixing the seven medicinal materials, placing in a ventilation chamber, and pulverizing into coarse powder with a full-automatic Chinese medicinal pulverizer;
(5) mixing the coarse powders uniformly to prepare mixed powder;
(6) and filling the mixed powder into non-woven fabric bags with the size of 7cm x 9cm, and sewing into finished products, wherein each bag contains 10g of the mixed powder, so that the traditional Chinese medicine eye fumigation preparation is obtained.
5. The preparation method of the traditional Chinese medicine eye applying preparation for treating juvenile accommodation myopia according to claim 4, wherein the slow fire in the step (2) is a slow fire with a temperature of 80-120 ℃; the Chinese angelica in the finished wine is prepared from the following Chinese angelica in percentage by mass: yellow wine is prepared in the ratio of 10 to 1.
6. The method for preparing a Chinese medicinal eye compress preparation for treating juvenile accommodation myopia according to claim 4, wherein the proper amount of water is just enough to submerge the medicine in step (3); the slow fire in the step (3) is 80-120 ℃.
7. The method for preparing a Chinese medicinal eye compress preparation for treating juvenile accommodation myopia according to claim 4, wherein the step (4) is performed by sieving with a sieve with 24 meshes; the drying conditions were: drying temperature: drying at 60-70 ℃ for: 3-5 h.
8. The use method of the traditional Chinese medicine eye compress preparation for treating the adolescent accommodation myopia according to any one of claims 1 to 7, which is characterized in that: soaking the medicated bag in cold water for 10min, heating, boiling for 5min, turning off fire, cooling, taking out the medicated bag in water, and wringing to dry.
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CN1830480A (en) * 2005-03-07 2006-09-13 湖南德海制药有限公司 Medicine for treating myopia and its preparation method
CN105560660A (en) * 2014-10-16 2016-05-11 刘强 Traditional Chinese medicine for treating nearsightedness and asthenopia
CN107158220A (en) * 2017-05-04 2017-09-15 王维维 A kind of Chinese medicine composition for preventing and treating teenage pseudomyopia and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1166353A (en) * 1997-01-11 1997-12-03 程宏亮 Oral medicine pill for curing myopia and amblyopia
CN1830480A (en) * 2005-03-07 2006-09-13 湖南德海制药有限公司 Medicine for treating myopia and its preparation method
CN105560660A (en) * 2014-10-16 2016-05-11 刘强 Traditional Chinese medicine for treating nearsightedness and asthenopia
CN107158220A (en) * 2017-05-04 2017-09-15 王维维 A kind of Chinese medicine composition for preventing and treating teenage pseudomyopia and preparation method thereof

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