CN103877430B - A kind of medicine and preparation method for the treatment of degeneration of macula - Google Patents
A kind of medicine and preparation method for the treatment of degeneration of macula Download PDFInfo
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Abstract
The invention discloses a kind of medicine and preparation method for the treatment of degeneration of macula, belong to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of: Herba Eragrostidis pilosae, Leontopodium leontopodioides (Willd.) Beauv., Nidus Vespae, Fructus Rubi, Fructus Momordicae charantiae, Herba Reineckeae Carneae, Fructus Solani Lyrati, Fructus Mahoniae, Clematis filamentosa Dunn, Semen Astragali Complanati, cypress, Fel python, Semen Euryales, Herba Cassiae Nomamis, Cortex Cinnamomi and Semen Fagopyri Esculenti; Selected by medicine of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has effect of detumescence improving eyesight, heat clearing and blood circulation promoting, anti-inflammatory analgetic and spleen diuretic, there is significant curative effect, short treating period, instant effect to treatment degeneration of macula, non-relapse after healing, safe and reliable, without any side effects, period in a medicine can normally work and live, special effect is practical, bring bright prospect to patient, be easy to be accepted by patient, should be widely promoted application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of degeneration of macula.
Background technology
The pathomechanism of degeneration of macula is mainly the Aging change of macular area structure, show as retinal pigment epithelium and digestive function decline is engulfed to visual cell external world dish film, make not digested dish film residual body retention in the former oar of basilar part cell, and discharge to extracellular, form glass-film wart, therefore after secondary pathological change, degeneration of macula is caused to occur, main and macular area long-term chronic photic damage in a word, choroidal vessels sclerosis, retinal pigment epithelium is aging relevant.
The natural result that degeneration of macula is normally degenerated advanced age, along with the age increases, retinal tissue is degenerated, thinning, causes macular function to decline.In the degeneration of macula patient of 10, be responsible for supply nutrition and just there will be seepage to amphiblestroid blood capillary, even form cicatrix, newborn abnormal blood vessel is also very common, the liquid of vascular leakage can destroy macula lutea, causes metamorphopsia, visual deterioration, overstocked cicatrix causes that central vision significantly declines, affect quality of life, even cecutiency, sometimes, degeneration of macula also can be caused by wound, infection or inflammation, this sick inherited genetic factors certain in addition.In western countries, degeneration of macula is the main cause causing more than 50 years old crowd blind, U.S.'s degeneration of macula cause blind to become these three kinds of commonly encountered diseases blinding number summations than glaucoma, cataract and ret diab also many.Also not low at Chinese degeneration of macula sickness rate, 60-69 year sickness rate is 6.04%-11.19%.Along with the quickening of Chinese population aging, this disease has obvious ascendant trend, but common people are inadequate with concern to the understanding of degeneration of macula.
Degeneration of macula is one of the most refractory oculopathy that international ophthalmic industry is generally acknowledged.Current effective Therapeutic Method for degeneration of macula also few U.S. now takes Avastin to treat degeneration of macula, obtained U.S. FDA and approved, and China only has Hongkong to carry out this medicine of employing to treat degeneration of macula at present.
Still imperfectly understand the cause of disease of degeneration of macula at present, Therapeutic Method need to continue research and development, and patient can pay close attention to the new therapy of this disease.Degeneration of macula is a kind of chronic ocular disease, and it can cause the sharply decline of central vision, and central vision to be daily routines necessary, as read, seeing the time, identify facial characteristics and driving etc.It is decline or the forfeiture of irreversible central vision, is difficult to cure again.Senile degeneration of macula mostly occurs more than 45 years old, and the age is larger, and sickness rate is higher.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of degeneration of macula; Selected by medicine of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and has effect of detumescence improving eyesight, heat clearing and blood circulation promoting, anti-inflammatory analgetic and spleen diuretic, there is significant curative effect, short treating period, instant effect to treatment degeneration of macula, non-relapse after healing, safe and reliable, without any side effects, period in a medicine can normally work and live, special effect is practical, bring bright prospect to patient, be easy to be accepted by patient, should be widely promoted application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for degeneration of macula, raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Raw material composition and the parts by weight of making described effective ingredient are:
Treat a preparation method for the medicine of degeneration of macula, comprise following processing step:
(1) Herba Eragrostidis pilosae, Leontopodium leontopodioides (Willd.) Beauv., Fructus Rubi, Herba Reineckeae Carneae, Fructus Mahoniae, Clematis filamentosa Dunn, Semen Astragali Complanati, cypress, Semen Euryales, Herba Cassiae Nomamis and Cortex Cinnamomi are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Nidus Vespae and Fructus Solani Lyrati are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) cleaned by Fructus Momordicae charantiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) cleaned by Fel python, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) be placed in pot by Semen Fagopyri Esculenti, it is yellow and savory spilling that intense fire is fried to surface, and taking-up cools, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the medicine for the treatment of degeneration of macula of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Eragrostidis pilosae: sweet in the mouth, light, cool in nature.Inducing diuresis for treating stranguria syndrome, heat clearing and blood circulation promoting.Cure mainly pyretic stranguria, stranguria caused by urinary stone, conjunctival congestion is itched bitterly, traumatic injury." Chinese herbal medicine handbook is commonly used in northeast " carries: " cure mainly urinary tract infection, pyelonephritis.”
Leontopodium leontopodioides (Willd.) Beauv.: mildly bitter flavor, cold in nature.Clearing away heat and cooling blood, diuresis.For acute nephritis.Someone think offset removing protein urine and hematuria have certain effect.
Nidus Vespae: sweet in the mouth, property is put down, and returns stomach warp.Removing the necrotic tissue and promoting granulation, anti-inflammatory analgetic, antiallergic.Be suitable for toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot, allergic constitution.Modern medicine study confirms, Nidus Vespae preparation has the effect promoting Immune Function.
Fructus Rubi: sweet in the mouth, property is put down, nontoxic; Enter liver, kidney two warp.Invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Control sexual impotence, seminal emission, frequency of micturition, incontinence of urine, asthenia, order is dark." not Lu " carries: " main QI invigorating is made light of one's life by commiting suicide, and order is sent out not white.
Fructus Momordicae charantiae: bitter in the mouth, cold in nature; Enter the heart, spleen, stomach three warp.Clearing away summer-heat washs heat, and improving eyesight is detoxified.Control calentura excessive thirst taking fluids profusely, heatstroke, dysentery, acute conjunctivitis pain, carbuncle erysipelas, malignant boil." Quanzhou book on Chinese herbal medicine " carries: " cure mainly dysphoria with smothery sensation to quench one's thirst taking fluids profusely, wind heat acute conjunctivitis, heatstroke dysentery.”
Herba Reineckeae Carneae: sweet in the mouth, cool in nature.Clearing away lung-heat to relieve cough, cooling blood for hemostasis.Cure mainly cough due to lung-heat, spitting of blood, has blood in stool, laryngopharynx swelling and pain; Cataract, carbuncle furuncle." Tian Bao book on Chinese herbal medicine " carries, and " clearing away lung-heat to relieve cough reduces phlegm.Control nosebleed, red skin ulcer, acute catarrhal conjunctivitis, traumatic injury "
Fructus Solani Lyrati: sour in the mouth, property is put down.Improving eyesight, pain relieving.Cure mainly dim eyesight conjunctival congestion, epiphora induced by wind, cataracta, toothache." Traditional Chinese Medicine in Sichuan will " carries: " control dental caries.”
Fructus Mahoniae: bitter in the mouth, cool in nature, return spleen, kidney, urinary bladder channel.Clearind deficient heat, the kidney invigorating dampness.Cure mainly osteopyrexia and fever, soreness of the waist and knees, dizziness and tinnitus, damp-heat diarrhea, leukorrhagia, stranguria with turbid discharge." modern Practical Chinese medicinal " carries: " for Tuberculous hectic fever, hectic fever due to YIN-deficiency, soreness of waist and knee, the diseases such as dizziness, tinnitus.”
Clematis filamentosa Dunn: bitter in the mouth, slightly cool in nature; GUIXIN, Liver Channel.Sedation and analgesia, clearing away liver-fire, mind calming god, blood pressure lowering, removing obstruction in the collateral to relieve pain.Main hypertension, insomnia, headache, numb limbs and tense tendons, wind-heat of liver channel, conjunctival congestion and swelling pain, acute toothache, rheumatic arthralgia.Modern medicine study confirms, Clematis filamentosa Dunn is to the symptom improved caused by hypertension, as headache, giddy, feeling of fullness in the head, numb limbs and tense tendons, insomnia etc. has good curative effect, and preliminary observation all has therapeutical effect to the hemiplegic patient caused patients with coronary heart disease and cerebrovas-cularaccident simultaneously.
Semen Astragali Complanati: sweet in the mouth, warm in nature; Enter liver, kidney channel.Invigorating the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, improving eyesight.Cure mainly the soreness of waist and knee joint that Liver and kidney void causes, dizziness and blurred vision, seminal emission premature ejaculation, the enuresis, frequent micturition, leukorrhagia, the diseases such as poor vision.Modern medicine study confirms, Semen Astragali Complanati containing retinoid material, fatty oil, tannin, have dispel the wind antipyretic, the effect of tonifying kidney for improving eyesight.
Cypress: go wind to detoxify, circulation of qi promoting exclusion, arteries and veins of invigorating blood circulation, the meridian dredging, wind-damp dispelling, clear pathogen heat.Can body fluid balance be kept, control excessive water and run off, so quite helpful to adult form skin, regulating action is had to hyperhidrosis and oiliness skin.And it promotes the function scabbed in addition, is conducive to the healing of wound.
Fel python: sweet-bitter flavor, cold in nature, slightly poisonous; Enter liver, spleen two warp.Dampness, parasite killing, improving eyesight.Control gastral cavity abdomen worm pain, dysentery, epilepsy disease, hemorrhoid, corneal nebula swells and ache." not Lu " carries, and " main trusted subordinate reveals pain, and hide skin ulcer in bottom, order swells and ache.”
Semen Euryales: sweet in the mouth, puckery, property is put down; Return spleen, kidney channel.Supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.Be usually used in nebulousurine, leukorrhagia, seminal emission, incontinence of urine, the turbid damp person that holds concurrently is especially suitable.According to Compendium of Material Medica record " Semen Euryales cure mainly arthralgia chiefly caused by damp pathogen, spinal column gonalgia, invigorating middle warmer, except sudden and violent disease, the strong will of beneficial vital essence, make normal hearing and eyesight, appetizing helps gas, quenches the thirst, after frying, property is partially warm, and gas is fragrant, strengthens spleen reinforcing and astringent or styptic treatment for spontaneous sweating effect.”
Herba Cassiae Nomamis: sweet-bitter flavor, cold in nature, nontoxic; Enter liver,kidney,spleen three warp.Liver heat removing and eyesight improving, and spleen diuretic.Cure mainly order flower, nyctalopia, migraine, edema, beriberi, jaundice." Guizhou side's medicine among the people collection " carries, and " diuresis, purges heat, antitussive, and the kidney invigorating is empty, clears away heart-fire, tomorrow.Modern medicine study confirms, Herba Cassiae Nomamis all herbal medicine, can control nyctalopia, mist, migraine ".
Cortex Cinnamomi: acrid in the mouth, sweet, extremely hot in nature; Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Semen Fagopyri Esculenti: sweet in the mouth, flat, cold in nature; Enter spleen, stomach, large intestine channel.Stomach invigorating restrains, and blood pressure lowering is stopped blooding.Be applicable to hypertension, blood capillary vulnerability is hemorrhage, prevents and treats apoplexy, retinal hemorrhage, pneumorrhagia; External convergence hidroschesis, antiinflammatory.
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has effect of detumescence improving eyesight, heat clearing and blood circulation promoting, anti-inflammatory analgetic and spleen diuretic, has significant curative effect, short treating period, instant effect, non-relapse after healing to treatment degeneration of macula, safe and reliable, without any side effects.
2, selected by medicine of the present invention, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, and period in a medicine can normally work and live, and special effect is practical, and bring bright prospect to patient, be easy to be accepted by patient, should be widely promoted application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Treat a preparation method for the medicine of degeneration of macula, comprise following processing step:
(1) Herba Eragrostidis pilosae, Leontopodium leontopodioides (Willd.) Beauv., Fructus Rubi, Herba Reineckeae Carneae, Fructus Mahoniae, Clematis filamentosa Dunn, Semen Astragali Complanati, cypress, Semen Euryales, Herba Cassiae Nomamis and Cortex Cinnamomi are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Nidus Vespae and Fructus Solani Lyrati are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(3) cleaned by Fructus Momordicae charantiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) cleaned by Fel python, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) be placed in pot by Semen Fagopyri Esculenti, it is yellow and savory spilling that intense fire is fried to surface, and taking-up cools, and grinds into powder, crosses 200 order fine powders, for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the medicine for the treatment of degeneration of macula of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every sheet 0.5g), warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of degeneration of macula, select the routine clinical observation of patients with macular degeneration 344 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 172 example, wherein male 86 example, women 86 example, 31 ~ 68 years old age, 49.5 years old mean age, the course of disease 8.1 years; Matched group 172 example, wherein male 86 example, women 86 example, 30 ~ 67 years old age, 48.5 years old mean age, the course of disease 7.9 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every sheet 0.5g), warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group uses Shi Tulun, follows the doctor's advice, every day one, in instillation eye conjunctival sac (position, canthus of nearly ear side), closes one's eyes and take a momentary rest after dripping, and forbids dropper and eye contact, and the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: symptom all disappears, eye recovers normal.
(2) effective: symptom obviously alleviates, eye takes a turn for the better to some extent.
(3) effective: symptom alleviates to some extent, and eye is clearly better.
(4) invalid: by treating rear symptom without alleviating or increasing the weight of.
4, result:
Select in the treatment group of medicine of the present invention, cure 81 examples, effective 56 examples, effective 33 examples, invalid 2 examples, cure rate 47.1%, total effective rate 98.8%.
42 examples are cured, effective 37 examples, effective 25 examples, invalid 68 examples, cure rate 24.4%, total effective rate 60.5% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, certain is gone into business, female, 32 years old, Tianjin people from Hebei District.Worse and worse, and the thing seen is sinuate, diminished for patient's vision, color is also thin out, and patient feels have individual shadow to keep off always at the moment, how to fall, remove hospital admission, be diagnosed as degeneration of macula, give Drug therapy of the present invention, after taking 1 course for the treatment of, symptom takes a turn for the better to some extent, after continuing to take 2 courses for the treatment of, and transference cure, recovery from illness, follows up a case by regular visits to so far without recurrence.
2, Wei, man, 38 years old, people from Discharge Engineering in Shanghai Jinshan District.Patient's eye is uncomfortable, does not see a little, thinks and just overworks, do not take notice of, vision declined always afterwards, removed examination in hospital, found that it is two degeneration of macula, take Drug therapy of the present invention, after taking 1 course for the treatment of, symptom alleviates to some extent, after taking 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
3, fourth, female, 52 years old, people from Fushun.Patient suffers from the stage occurred frequently of degeneration of macula, and along with the continuous growth at age, every function of health, all in declaration strike, takes Drug therapy of the present invention, after taking 1 course for the treatment of, symptom is alleviated to some extent, after taking 3 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after 2 years without recurrence.
4, Xue, man, 45 years old, people from Liaoyuan, Jilin.The right visual deterioration of patient's readme 1 first quarter moon, shadow is had before conscious right eye, depending on thing obfuscation distortion, without furious, ophthalmalgia history, before 3 years, left eye once had kindred circumstances, recovery is had through treatment about one year vision, nearest patient work is nervous, check: the right 4.6(0.4 of vision), left 4.9(0.8), two external eyes no abnormality seen, refractive media is clear, little pupil examination of ocular fundus: Binocular vison nipple is normal, arteria retina is slightly thin, vein is normal, right eye macula area slightly swells, there is yellow-white pointing object, left eye macula area pigment is disorderly, central fovea luminous reflectance is dim, upon somebody's introduction, take Drug therapy of the present invention, after taking 1 course for the treatment of, symptom alleviates to some extent, after taking 3 courses for the treatment of, transference cure, recovery from illness, follow up a case by regular visits to so far without recurrence.
5, leaf, female, 57 years old, people from Langfang in Hebei Province.Eye is uncomfortable, and suffer from age-related macular degeneration for many years, left vision is only 0.06, right vision is 0.2, remove hospital admission, be diagnosed as age-related macular degeneration, give Drug therapy of the present invention, after taking 1 course for the treatment of, symptom is alleviated to some extent, after taking 3 courses for the treatment of, and transference cure, recovery from illness, follows up a case by regular visits to after 2 years without recurrence.
6, the Yan, man, 63 years old, Distributions in Liaocheng of Shandong Province people.Patient has suffered from maculopathy, right vision 0.1, left vision index, cornea of both eyes is transparent, Qian Fangqing, and pupil can to light emission, crystal little cloudy, two macular area foveal reflexs disappear, and Magnifying chromoscopy is disorderly, the loose property glass-film wart of companion, removes hospital admission, used multiple Drug therapy, after treating 2 courses for the treatment of, symptom is clearly better, after continuing to take 2 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to so far without recurrence.
Claims (5)
1. treat a medicine for degeneration of macula, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Eragrostidis pilosae 51 ~ 75 parts of Leontopodium leontopodioides (Willd.) Beauv. 49 ~ 73 parts of Nidus Vespae 45 ~ 69 portions of Fructus Rubies 45 ~ 69 parts
Fructus Momordicae charantiae 43 ~ 67 parts of Herba Reineckeae Carneaes 42 ~ 66 parts of Fructus Solani Lyratis 42 ~ 66 parts of Fructus Mahoniaees 40 ~ 64 parts
Clematis filamentosa Dunn 39 ~ 63 parts of Semen Astragali Complanatis 39 ~ 63 parts of cypresses 37 ~ 61 parts of Fel pythons 35 ~ 59 parts
22 ~ 46 parts, Semen Euryales 31 ~ 55 parts of Herba Cassiae Nomamis 30 ~ 54 portions of Cortex Cinnamomis 26 ~ 50 portions of Semen Fagopyri Esculentis.
2. a kind of medicine for the treatment of degeneration of macula according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Eragrostidis pilosae 54 ~ 70 parts of Leontopodium leontopodioides (Willd.) Beauv. 52 ~ 68 parts of Nidus Vespae 48 ~ 64 portions of Fructus Rubies 48 ~ 64 parts
Fructus Momordicae charantiae 47 ~ 63 parts of Herba Reineckeae Carneaes 46 ~ 62 parts of Fructus Solani Lyratis 46 ~ 62 parts of Fructus Mahoniaees 44 ~ 60 parts
Clematis filamentosa Dunn 43 ~ 59 parts of Semen Astragali Complanatis 43 ~ 59 parts of cypresses 41 ~ 57 parts of Fel pythons 39 ~ 55 parts
26 ~ 42 parts, Semen Euryales 35 ~ 51 parts of Herba Cassiae Nomamis 34 ~ 50 portions of Cortex Cinnamomis 30 ~ 46 portions of Semen Fagopyri Esculentis.
3. a kind of medicine for the treatment of degeneration of macula according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Eragrostidis pilosae 58 ~ 66 parts of Leontopodium leontopodioides (Willd.) Beauv. 56 ~ 64 parts of Nidus Vespae 52 ~ 60 portions of Fructus Rubies 52 ~ 60 parts
Fructus Momordicae charantiae 51 ~ 59 parts of Herba Reineckeae Carneaes 50 ~ 58 parts of Fructus Solani Lyratis 50 ~ 58 parts of Fructus Mahoniaees 48 ~ 56 parts
Clematis filamentosa Dunn 47 ~ 55 parts of Semen Astragali Complanatis 47 ~ 55 parts of cypresses 45 ~ 53 parts of Fel pythons 43 ~ 51 parts
30 ~ 38 parts, Semen Euryales 39 ~ 47 parts of Herba Cassiae Nomamis 38 ~ 46 portions of Cortex Cinnamomis 34 ~ 42 portions of Semen Fagopyri Esculentis.
4. a kind of medicine for the treatment of degeneration of macula according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Herba Eragrostidis pilosae 62 parts of Leontopodium leontopodioides (Willd.) Beauv. 60 parts of Nidus Vespae 56 portions of Fructus Rubies 56 parts
Fructus Momordicae charantiae 55 parts of Herba Reineckeae Carneaes 54 parts of Fructus Solani Lyratis 54 parts of Fructus Mahoniaees 52 parts
Clematis filamentosa Dunn 51 parts of Semen Astragali Complanatis 51 parts of cypresses 49 parts of Fel pythons 47 parts
34 parts, Semen Euryales 43 parts of Herba Cassiae Nomamis 42 portions of Cortex Cinnamomis 38 portions of Semen Fagopyri Esculentis.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of degeneration of macula, it is characterized in that: comprise following processing step:
(1) Herba Eragrostidis pilosae, Leontopodium leontopodioides (Willd.) Beauv., Fructus Rubi, Herba Reineckeae Carneae, Fructus Mahoniae, Clematis filamentosa Dunn, Semen Astragali Complanati, cypress, Semen Euryales, Herba Cassiae Nomamis and Cortex Cinnamomi are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Nidus Vespae and Fructus Solani Lyrati are put into container, carry out pulverization process, grind into powder, cross 180 orders and obtain fine powder, for subsequent use;
(3) cleaned by Fructus Momordicae charantiae, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(4) cleaned by Fel python, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) be placed in pot by Semen Fagopyri Esculenti, it is yellow and savory spilling that intense fire is fried to surface, and taking-up cools, and grinds into powder, crosses 200 orders and obtains fine powder, for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make tablet, obtain the medicine of described treatment degeneration of macula.
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| CN1678342A (en) * | 2002-07-02 | 2005-10-05 | 加州大学评议会 | Treatment for eye disorder |
| CN101628088A (en) * | 2009-07-31 | 2010-01-20 | 刘昌州 | Traditional Chinese medicine composition for treating dermatosis |
| CN102813780A (en) * | 2012-09-17 | 2012-12-12 | 通化师范学院 | Chinese herbal medicinal compound preparation used for treating macular degeneration of old people and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1678342A (en) * | 2002-07-02 | 2005-10-05 | 加州大学评议会 | Treatment for eye disorder |
| CN101628088A (en) * | 2009-07-31 | 2010-01-20 | 刘昌州 | Traditional Chinese medicine composition for treating dermatosis |
| CN102813780A (en) * | 2012-09-17 | 2012-12-12 | 通化师范学院 | Chinese herbal medicinal compound preparation used for treating macular degeneration of old people and preparation method thereof |
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