CN106491730A - A kind of treat Chinese medicine composition of glaucoma and preparation method thereof - Google Patents
A kind of treat Chinese medicine composition of glaucoma and preparation method thereof Download PDFInfo
- Publication number
- CN106491730A CN106491730A CN201710002663.0A CN201710002663A CN106491730A CN 106491730 A CN106491730 A CN 106491730A CN 201710002663 A CN201710002663 A CN 201710002663A CN 106491730 A CN106491730 A CN 106491730A
- Authority
- CN
- China
- Prior art keywords
- parts
- semen
- glaucoma
- chinese medicine
- medicine composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/09—Lichens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Present invention offer is a kind of to treat Chinese medicine composition of glaucoma and preparation method thereof, and the Chinese medicine composition is made up of the raw material of following weight portion:5 10 parts of Folium Ginkgo, 5 10 parts of Cladonia alpestris (L.) Rabenh., 5 10 parts of Semen Plantaginiss, 10 15 parts of the Radix Paeoniae Alba, 7 12 parts of Herba Senecionis Scandentiss, 10 15 parts of Radix et Caulis Opuntiae Dillenii, 10 15 parts of Spica Prunellae, 25 parts of Blumeae preparatum Tabellae, 7 12 parts of Semen Euryaless, 36 parts of Semen Pharbitidiss, 7 12 parts of Fructus Ligustri Lucidi, 10 15 parts of Flos Buddlejae.The present invention can not only reduce intraocular pressure, moreover it is possible to promote the microcirculation of circumference of eyes, protect optic nerve, improve antioxidant ability of organism, have good curative effect to glaucoma, have no side effect safely, and effective percentage has good popularizing value up to 97%.
Description
Technical field
The present invention relates to technical field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating glaucoma and its preparation side
Method.
Background technology
Glaucoma refer to as intraocular pressure increases and cause regarding nipple infringement and a kind of oculopathy of visual disorder, normal eyes
10-21mmHg is pressed in, is pathological phenomenon more than 24mmHg.As pathologic intraocular pressure has exceeded the tolerant degree of optic nerve institute,
Cause optic atrophy, cause the loss of the apoptosis and optic nerve fiber of pattern of retinal ganglion cells (RGC) irreversibility, so as to cause
Visual function damage, defect of visual field may cause blind at any time.Glaucoma morbidity is rapid, and hazardness is big, is blinding main at present
One of property oculopathy, World Health Organization (WHO) has been classified as second diseases causing blindness.
Treatment of the modern medical service technology to glaucoma, how using therapeutic method of surgery, cuts art, trabecular resection in such as iris week
Art, valve implanation, goniotomy, room angle exclusion, cyclocryoapplication, diathermanous and Light utilization etc..But
Costly, there is higher requirement to the condition that performs the operation, the especially technical merit of doctor.In addition operative treatment is merely resting on
In treatment to " disease ", do not have to solve the problems, such as " because ", thoroughly change eye microcirculation, therefore still suffer from recur can
Energy.In addition to operative therapy, the medicines such as choline, pantothenic acid, rutacultin, vitamin B complex, vitamin C, vitamin E are also supplemented
Therapeutic Method.These drug treatments have certain clinical effectiveness, but are usually unable to thoroughly cure symptoms of glaucoma, and
And the application of some Western medicine is easily caused to damage to heart, Liver and kidney, large side effects, long-term taking are very big to body harm.Motherland
Medical science thinks that glaucoma belongs to pupil god's disease, and when ancient times fall ill according to which, in pupil god, the change pictograph of color is described as " in glaucoma
Barrier ", " absolute glaucoma with cataract ", " bluish glaucoma ", " black glaucoma ", " glaucoma ", are listed within " five kinds of glaucoma " category, or with normal
Witness awaits your instructions entitled " mydriasis ", or is listed in the categories such as " thunder-headache ", " migraine ", its basic pathogenesis be by wind, fire, expectorant,
Strongly fragrant and imbalance of YIN and YANG, causes qi-blood disharmony, and passages through which vital energy circulates is unfavorable, and sweat pore obstruction in mesh, caused by stagnation of QI-blood and body fluid in eyeball.Inventor's root
According to clinical practice for many years, it is proposed that technical scheme, for glaucoma has good therapeutic effect.
Content of the invention
For the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for treating glaucoma and its preparation side
Method.
For realizing that object above, the present invention are achieved by the following technical programs:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:Folium Ginkgo 5-10 parts, Cladonia alpestris (L.) Rabenh.
5-10 parts, Semen Plantaginiss 5-10 parts, Radix Paeoniae Alba 10-15 parts, Herba Senecionis Scandentiss 7-12 parts, Radix et Caulis Opuntiae Dillenii 10-15 parts, Spica Prunellae 10-15 parts, Blumeae preparatum Tabellae
2-5 parts, Semen Euryaless 7-12 parts, Semen Pharbitidiss 3-6 parts, Fructus Ligustri Lucidi 7-12 parts, Flos Buddlejae 10-15 parts.
Preferably, it is made up of the raw material of following weight portion:8 parts of Folium Ginkgo, 7 parts of Cladonia alpestris (L.) Rabenh., 8 parts of Semen Plantaginiss, 11 parts of the Radix Paeoniae Alba,
10 parts of Herba Senecionis Scandentiss, 12 parts of Radix et Caulis Opuntiae Dillenii, 11 parts of Spica Prunellae, 4 parts of Blumeae preparatum Tabellae, 10 parts of Semen Euryaless, 5 parts of Semen Pharbitidiss, 10 parts of Fructus Ligustri Lucidi, Flos Buddlejae
12 parts.
Preferably, it is made up of the raw material of following weight portion:7 parts of Folium Ginkgo, 8 parts of Cladonia alpestris (L.) Rabenh., 8 parts of Semen Plantaginiss, 13 parts of the Radix Paeoniae Alba,
11 parts of Herba Senecionis Scandentiss, 13 parts of Radix et Caulis Opuntiae Dillenii, 12 parts of Spica Prunellae, 4 parts of Blumeae preparatum Tabellae, 10 parts of Semen Euryaless, 4 parts of Semen Pharbitidiss, 9 parts of Fructus Ligustri Lucidi, Flos Buddlejae
14 parts.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, step are as follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 110-120 DEG C of heating furnace, rolling heating
30-40s, obtains material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 8- is added
The water of 10 times of quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continues to decoct 1-2h, mistake
Filter, obtains filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stir
Mix uniformly, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, be prepared into corresponding pharmaceutical dosage form.
Preferably, the dosage form is tablet, granule, decoction, capsule or pill.
In the present invention, effect of each raw material is as follows:
Folium Ginkgo:Mild-natured, sweet in the mouth, hardship, puckery, thoughts of returning home warp, lung meridian, have functions that astringing the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.
Cladonia alpestris (L.) Rabenh.:Mild-natured, lightly seasoned, Return liver, stomach, have functions that suppressing the hyperactive liver and easing the stomach, regulating menstruation, hemostasis.
Semen Plantaginiss:Cold nature, sweet in the mouth return kidney, liver, lung, small intestine meridian, with clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminating the phlegm
Effect.
The Radix Paeoniae Alba:Cold nature, bitter in the mouth, acid, Return liver, spleen channel, have functions that smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Herba Senecionis Scandentiss:Cold in nature, bitter in the mouth, Return liver, lung meridian, with heat-clearing and toxic substances removing, cool blood detumescence, liver heat removing and eyesight improving, parasite killing pain relieving it
Effect.
Radix et Caulis Opuntiae Dillenii:Cold in nature, bitter in the mouth returns stomach, have functions that promoting flow of QI and blood, cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling.
Spica Prunellae:Cold in nature, acrid in the mouth, hardship, return liver warp, gallbladder meridian, have functions that relieving inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence, with controlling mesh
Red swell and ache, mesh pearl nyctalgia, dizziness of having a headache, scrofula, goiter, acute mastitis swell and ache, thyromegaly, tuberculous lymphadenitiss, cyclomastopathy, height
Blood pressure.
Blumeae preparatum Tabellae:Cold in nature, bitter in the mouth, pungent, puckery, have functions that heat clearing away, detumescence, pain relieving.
Semen Euryaless:Mild-natured, sweet in the mouth is puckery, returns spleen, kidney channel, have functions that invigorating the spleen and replenishing QI, supplementing the kidney to control the nocturnal, eliminating dampness and arresting leucorrhea.
Semen Pharbitidiss:Cold in nature, bitter in the mouth, return lung, kidney, large intestine channel are washed drink, parasite killing with removing water retention by purgation relieving constipation, expectorant and attack long-pending effect.
Fructus Ligustri Lucidi:Cool in nature, sweet in the mouth, hardship return liver and kidney channel, have functions that nourishing the liver and kidney, improving eyesight black hair.
Flos Buddlejae:Cold nature, sweet in the mouth, return liver warp, have functions that heat clearing away nourishing the liver, pathogenic fire purging, improving acuity of vision and removing nebula.
Beneficial effect of the present invention:The mutual compatibility of each medicine in the present invention, based on liver and kidney tonifying, helps with heat clearing away, pathogenic fire purging, work
Blood, liver heat removing, can not only reduce intraocular pressure, moreover it is possible to promote the microcirculation of circumference of eyes, protect optic nerve, improve body antioxidation energy
Power, has good curative effect, has no side effect safely to glaucoma, and effective percentage has good popularizing value up to 97%.
Specific embodiment
Purpose, technical scheme and advantage for making the embodiment of the present invention is clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment, rather than whole embodiments.Embodiment in based on the present invention, those of ordinary skill in the art are not being made
The every other embodiment obtained under the premise of creative work, belongs to the scope of protection of the invention.
Embodiment 1:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:8 parts of Folium Ginkgo, Cladonia alpestris (L.) Rabenh. 7
Part, 8 parts of Semen Plantaginiss, 11 parts of the Radix Paeoniae Alba, 10 parts of Herba Senecionis Scandentiss, 12 parts of Radix et Caulis Opuntiae Dillenii, 11 parts of Spica Prunellae, 4 parts of Blumeae preparatum Tabellae, 10 parts of Semen Euryaless, lead a cow
5 parts of son, 10 parts of Fructus Ligustri Lucidi, 12 parts of Flos Buddlejae.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, step are as follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 110 DEG C of heating furnace, rolling heating 35s,
Obtain material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 8 times are added
The water of quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continue to decoct 1.5h, filter,
Obtain filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stir
Mix uniformly, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, prepare piece agent.
Embodiment 2:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:7 parts of Folium Ginkgo, Cladonia alpestris (L.) Rabenh. 8
Part, 8 parts of Semen Plantaginiss, 13 parts of the Radix Paeoniae Alba, 11 parts of Herba Senecionis Scandentiss, 13 parts of Radix et Caulis Opuntiae Dillenii, 12 parts of Spica Prunellae, 4 parts of Blumeae preparatum Tabellae, 10 parts of Semen Euryaless, lead a cow
4 parts of son, 9 parts of Fructus Ligustri Lucidi, 14 parts of Flos Buddlejae.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, step are as follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 115 DEG C of heating furnace, rolling heating 35s,
Obtain material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 9 times are added
The water of quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continues to decoct 2h, filters, obtain
Filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stir
Mix uniformly, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, be prepared into decoction.
Embodiment 3:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:10 parts of Folium Ginkgo, Cladonia alpestris (L.) Rabenh. 8
Part, 8 parts of Semen Plantaginiss, 12 parts of the Radix Paeoniae Alba, 9 parts of Herba Senecionis Scandentiss, 12 parts of Radix et Caulis Opuntiae Dillenii, 12 parts of Spica Prunellae, 3 parts of Blumeae preparatum Tabellae, 9 parts of Semen Euryaless, Semen Pharbitidiss 3
Part, 8 parts of Fructus Ligustri Lucidi, 13 parts of Flos Buddlejae.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, step are as follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 120 DEG C of heating furnace, rolling heating 30s,
Obtain material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 8 times are added
The water of quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continues to decoct 1h, filters, obtain
Filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stir
Mix uniformly, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, be prepared into capsule.
Embodiment 4:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:10 parts of Folium Ginkgo, Cladonia alpestris (L.) Rabenh. 5
Part, 10 parts of Semen Plantaginiss, 10 parts of the Radix Paeoniae Alba, 12 parts of Herba Senecionis Scandentiss, 10 parts of Radix et Caulis Opuntiae Dillenii, 15 parts of Spica Prunellae, 2 parts of Blumeae preparatum Tabellae, 12 parts of Semen Euryaless, lead a cow
3 parts of son, 12 parts of Fructus Ligustri Lucidi, 10 parts of Flos Buddlejae.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, step are as follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 110 DEG C of heating furnace, rolling heating 40s,
Obtain material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 10 are added
The water of times quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continue to decoct 2h, filter,
Obtain filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stir
Mix uniformly, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, be prepared into pill.
Embodiment 5:
A kind of Chinese medicine composition for treating glaucoma, is made up of the raw material of following weight portion:5 parts of Folium Ginkgo, Cladonia alpestris (L.) Rabenh. 10
Part, 5 parts of Semen Plantaginiss, 15 parts of the Radix Paeoniae Alba, 7 parts of Herba Senecionis Scandentiss, 15 parts of Radix et Caulis Opuntiae Dillenii, 10 parts of Spica Prunellae, 5 parts of Blumeae preparatum Tabellae, 7 parts of Semen Euryaless, Semen Pharbitidiss 6
Part, 7 parts of Fructus Ligustri Lucidi, 15 parts of Flos Buddlejae.
The preparation method of the Chinese medicine composition for the treatment of glaucoma, with embodiment 4.
Pharmacology's detection is carried out to medicine obtained in the embodiment of the present invention, wherein, toxicity drug effect reality is carried out using white mice
Test, do not find obvious toxic and side effects, illustrate that safety of medicine prepared by the embodiment of the present invention has no toxic side effect.The medicine that will be prepared
Clinic is further applied, through clinical drug best results prepared by Clinical detection, embodiment 1.
Clinical case:
Case selection:The glaucoma patient 100 that makes a definite diagnosis, wherein male 56, women 44 is selected, the age is in 35-70
Between year, the mean age, before patient's medication, in more than 30mmHg, fluctuation range was more than intraocular pressure meansigma methodss within 24 hours at 46 years old
8mmHg.
1st, diagnostic criteria:Recurrent exerbation visual deterioration (still declines containing Postoperative visual acuity or open angle glaucoma visual deterioration is slow
Slowly, non-evident sympton patient) sometimes eye pain, ictal iridization, platycoria, intraocular pressure 32-75mmHg, optic atrophy, repeatedly
Outbreak is blind to be less than 1 month.
2nd, Therapeutic Method:The Chinese medicinal tablet prepared using the embodiment of the present invention 1,2g/ pieces, 2 times a day, 2 every time, warm water
Take, be within 7 days 1 course for the treatment of, treatment cycle is 3 courses for the treatment of.
3rd, Outcome measure
Effective:Intraocular pressure control all disappears in below 21mmHg, primary symptom and adjoint disease;
Effectively:Intraocular pressure control disappears in below 21mmHg, primary symptom, mitigates with disease;
Invalid:Intraocular pressure is unchanged, and simultaneous phenomenon does not change.
4th, therapeutic outcome:
After taking 3 courses for the treatment of, in 100 glaucoma patients, effective 64, effective 33, invalid 3, total effective rate reaches
97%.
Model case:
Zhang, 54 years old, suffers from glaucoma and has 3 years, and intraocular pressure is sometime up to 50mmHg, and fluctuation range is more than within 24 hours
12mmHg, eyeball distending pain, platycoria, after taking 3 courses for the treatment of of medicine of the embodiment of the present invention 1, eyeball distending pain disappears, follow-up one
Year does not recur.
It should be noted that herein, such as first and second or the like relational terms are used merely to a reality
Body or operation are made a distinction with another entity or operation, and are not necessarily required or implied these entities or deposit between operating
In any this actual relation or order.And, term " including ", "comprising" or its any other variant are intended to
Nonexcludability includes, so that a series of process, method, article or equipment including key elements not only includes that those will
Element, but also other key elements including being not expressly set out, or also include for this process, method, article or equipment
Intrinsic key element.In the absence of more restrictions, the key element for being limited by sentence "including a ...", it is not excluded that
Also there is other identical element in process, method, article or equipment including the key element.
Above example only in order to technical scheme to be described, rather than a limitation;Although with reference to the foregoing embodiments
The present invention has been described in detail, it will be understood by those within the art that:Which still can be to aforementioned each enforcement
Technical scheme described in example is modified, or carries out equivalent to which part technical characteristic;And these modification or
Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (5)
1. a kind of Chinese medicine composition for treating glaucoma, it is characterised in that be made up of the raw material of following weight portion:Folium Ginkgo 5-10
Part, Cladonia alpestris (L.) Rabenh. 5-10 parts, Semen Plantaginiss 5-10 parts, Radix Paeoniae Alba 10-15 parts, Herba Senecionis Scandentiss 7-12 parts, Radix et Caulis Opuntiae Dillenii 10-15 parts, Spica Prunellae 10-
15 parts, Blumeae preparatum Tabellae 2-5 parts, Semen Euryaless 7-12 parts, Semen Pharbitidiss 3-6 parts, Fructus Ligustri Lucidi 7-12 parts, Flos Buddlejae 10-15 parts.
2. as claimed in claim 1 treatment glaucoma Chinese medicine composition, it is characterised in that by the raw material group of following weight portion
Into:8 parts of Folium Ginkgo, 7 parts of Cladonia alpestris (L.) Rabenh., 8 parts of Semen Plantaginiss, 11 parts of the Radix Paeoniae Alba, 10 parts of Herba Senecionis Scandentiss, 12 parts of Radix et Caulis Opuntiae Dillenii, 11 parts of Spica Prunellae, Chinese mugwort
4 parts of piece, 10 parts of Semen Euryaless, 5 parts of Semen Pharbitidiss, 10 parts of Fructus Ligustri Lucidi, 12 parts of Flos Buddlejae.
3. as claimed in claim 1 treatment glaucoma Chinese medicine composition, it is characterised in that by the raw material group of following weight portion
Into:7 parts of Folium Ginkgo, 8 parts of Cladonia alpestris (L.) Rabenh., 8 parts of Semen Plantaginiss, 13 parts of the Radix Paeoniae Alba, 11 parts of Herba Senecionis Scandentiss, 13 parts of Radix et Caulis Opuntiae Dillenii, 12 parts of Spica Prunellae, Chinese mugwort
4 parts of piece, 10 parts of Semen Euryaless, 4 parts of Semen Pharbitidiss, 9 parts of Fructus Ligustri Lucidi, 14 parts of Flos Buddlejae.
4. as described in claim 1-3 is arbitrary treatment glaucoma Chinese medicine composition preparation method, it is characterised in that step
As follows:
1) Folium Ginkgo, the Radix Paeoniae Alba and Radix et Caulis Opuntiae Dillenii are crushed, adds and be pre-heated in 110-120 DEG C of heating furnace, rolling heating 30-
40s, obtains material I;
2) Blumeae preparatum Tabellae is ground crushing, obtains material II;
3) by Cladonia alpestris (L.) Rabenh., Semen Plantaginiss, Herba Senecionis Scandentiss, Spica Prunellae, Semen Euryaless, Semen Pharbitidiss, Fructus Ligustri Lucidi, Flos Buddlejae mixing, 8-10 times is added
The water of quality, decocts after extracting 1h, is added thereto to step 1) the uncooled material I of fresh baked, continue to decoct 1-2h, filter,
Obtain filtrate;
4) filtrate is carried out concentrating under reduced pressure, obtains the clear paste that relative density is 1.05 (60 DEG C), be added thereto to material II, stirring is
Even, obtain mixed liquor;
5) pharmaceutically acceptable carrier is added in mixed liquor, be prepared into corresponding pharmaceutical dosage form.
5. the preparation method of the Chinese medicine composition for the treatment of glaucoma as claimed in claim 4, it is characterised in that the dosage form is
Tablet, granule, decoction, capsule or pill.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710002663.0A CN106491730A (en) | 2017-01-03 | 2017-01-03 | A kind of treat Chinese medicine composition of glaucoma and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710002663.0A CN106491730A (en) | 2017-01-03 | 2017-01-03 | A kind of treat Chinese medicine composition of glaucoma and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106491730A true CN106491730A (en) | 2017-03-15 |
Family
ID=58344959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710002663.0A Pending CN106491730A (en) | 2017-01-03 | 2017-01-03 | A kind of treat Chinese medicine composition of glaucoma and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106491730A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108175818A (en) * | 2018-03-07 | 2018-06-19 | 黑龙江中医药大学 | A kind of Chinese medicine composition for treating glaucoma and its preparation method and application |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104398543A (en) * | 2014-12-05 | 2015-03-11 | 上海信谊百路达药业有限公司 | Application of folium ginkgo composition to preparation of medicine for preventing or treating glaucoma |
-
2017
- 2017-01-03 CN CN201710002663.0A patent/CN106491730A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104398543A (en) * | 2014-12-05 | 2015-03-11 | 上海信谊百路达药业有限公司 | Application of folium ginkgo composition to preparation of medicine for preventing or treating glaucoma |
Non-Patent Citations (1)
Title |
---|
谭浅等: ""三子加明汤对急性高眼压兔视网膜保护作用的实验研究"", 《湖南中医学院学报》 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108175818A (en) * | 2018-03-07 | 2018-06-19 | 黑龙江中医药大学 | A kind of Chinese medicine composition for treating glaucoma and its preparation method and application |
CN108175818B (en) * | 2018-03-07 | 2020-12-22 | 黑龙江中医药大学 | Traditional Chinese medicine composition for treating glaucoma and preparation method and application thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103656290B (en) | Medicine for treating optic atrophy and preparation method of medicine | |
CN102327443B (en) | Method for preparing traditional Chinese medicine (TCM) lotion for treating pruritus bedsore | |
CN108653429B (en) | Traditional Chinese medicine composition for treating hordeolum disease and application thereof | |
CN102198227B (en) | Method for preparing Chinese medicine for treating yin-deficiency glaucoma | |
CN102824622B (en) | Preparation method of traditional Chinese medicine lotion for treating closed fracture with syndrome of palpitation | |
CN106491730A (en) | A kind of treat Chinese medicine composition of glaucoma and preparation method thereof | |
CN107929670A (en) | A kind of Medicated eye-mask for treating eye-blurred and preparation method thereof | |
CN106362089A (en) | External medicine for treating eye diseases | |
CN110433232A (en) | A kind of compound huang lian granules of external application and preparation method thereof | |
CN105213887A (en) | One is used for the treatment of glaucomatous Chinese medicine composition | |
CN104523981A (en) | Traditional Chinese medicine preparation for treating optic neuritis and preparation method | |
CN101301447B (en) | Chinese medicinal composition for treating epilepsy | |
CN114452365B (en) | Traditional Chinese medicine preparation for treating chalazion | |
CN102579724B (en) | Chinese medicine composition for treating glaucoma | |
CN103610797B (en) | Traditional Chinese medicine composition for treating keratoconjunctivitis due to congestion and excess of dampness-heat | |
CN104324139B (en) | A kind of pharmaceutical composition treating xerophthalmia | |
CN104258113B (en) | A kind of Chinese medicine composition for the treatment of cerebral hemorrhage | |
CN106267023A (en) | A kind of active pills for improving acuity of sight for optic atrophy | |
CN105168963A (en) | Traditional Chinese medicinal composition for treating xerophthalmia | |
CN104771638A (en) | Traditional Chinese medicine composition for treating optic atrophy | |
CN104524036A (en) | Traditional Chinese medicine preparation for treating optic neuritis and preparation method thereof | |
CN1062165C (en) | Medicinal cream for curing myopia and weak visual acuity | |
CN104587364A (en) | Traditional Chinese medicine composition used for treating uveitis | |
CN105816723A (en) | Traditional Chinese medicine composition for treating keratohelcosis | |
CN106983820A (en) | Chinese medicine composition and preparation method for treating cataract |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170315 |