CN104587364A - Traditional Chinese medicine composition used for treating uveitis - Google Patents
Traditional Chinese medicine composition used for treating uveitis Download PDFInfo
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Abstract
The invention belongs to the field of Traditional Chinese medicine technology, and especially relates to a traditional Chinese medicine composition used for treating uveitis. The traditional Chinese medicine composition is prepared from the following traditional Chinese raw materials in parts by weight: 3-5 parts of schizonepeta, 3-5 parts of saposhnikovia, 5-10 parts of Japanese violet, 3-5 parts of fried coix seed, 5-10 parts of chicken's egg membrane, 5-8 parts of rice-paper plant pith, 5-8 parts of fetid cassia seed, 3-5 parts of vitex seed, 3-5 parts of dodder,1-3 parts of amomum, 3-5 parts of prunella, 1-3 parts of pubescent angelica,5-8 parts of pine needle, 5-8 parts of mulberry leaf, 3-5 parts of honeysuckles, 5-8 parts of radix scutellariae, 5-8 parts of phellodendron, 3-5 parts of leonurus fruit and 3-5 parts of red peony. According to the preparation method, the traditional Chinese medicine composition can be prepared into eyedrops. The traditional Chinese medicine composition disclosed by the invention is quick in effectiveness and high in cure rate when used for treating the uveitis, and has no antibiotics and little toxic or side effects.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly one treats uveitic Chinese medicine composition.
Background technology
Uveitis refers to iris, corpus ciliare, choroidal inflammation; Iris and capsulociliary blood supply are all greater ring of iris, therefore the two often inflammation simultaneously, and be generically and collectively referred to as iridocyclitis.If choroid is inflammation simultaneously also, be then called uveitis.Be a kind of oculopathy being mainly in person between twenty and fifty, of a great variety, the cause of disease is quite complicated, and malpractice can cause blind, in diseases causing blindness, occupy critical role, has caused worldwide attention.Because its morbidity and Mechanisms of recurrence still imperfectly understand, therefore its prevention is had no way of handling, and therapeutic effect is also very undesirable.Therefore, reasonable and effective medicine, become a problem demanding prompt solution in field of ophthalmology.
Chinese patent (CN103006847A) discloses one and treats uveitic eye drop and preparation method thereof, and Chinese Medicine and Clavicular Western medicine is made, and treats, but zest is strong, and cure rate has much room for improvement, and possesses certain limitation.
Summary of the invention
The object of this invention is to provide one and treat uveitic Chinese medicine composition, there is instant effect, cure rate is high, advantage that toxic and side effects is little, and there is simple and easy to do preparation method.
The invention provides one and treat uveitic Chinese medicine composition, formulated by the raw material of Chinese medicine of following parts by weight: Herba Schizonepetae 3 ~ 5 parts, Radix Saposhnikoviae 3 ~ 5 parts, Herba Violae japonicae 5 ~ 10 parts, Semen Coicis (parched) 3 ~ 5 parts, Membrana Follicularis ovi 5 ~ 10 parts, white Medulla Tetrapanacis 5 ~ 8 parts, Semen Cassiae 5 ~ 8 parts, Fructus Viticis 3 ~ 5 parts, Semen Cuscutae 3 ~ 5 parts, Fructus Amomi 1 ~ 3 part, Spica Prunellae 3 ~ 5 parts, Qiang's Radix Angelicae Pubescentis 1 ~ 3 part, 5 ~ 8 parts, Folium Pini, 5 ~ 8 parts, Folium Mori, Flos Lonicerae 3 ~ 5 parts, Radix Scutellariae 5 ~ 8 parts, Cortex Phellodendri 5 ~ 8 parts, Fructus Leonuri 3 ~ 5 parts, Radix Paeoniae Rubra 3 ~ 5 parts.
More preferably formulated by the raw material of Chinese medicine of following parts by weight: Herba Schizonepetae 4 parts, Radix Saposhnikoviae 4 parts, Herba Violae japonicae 7 parts, Semen Coicis (parched) 4 parts, Membrana Follicularis ovi 8 parts, white Medulla Tetrapanacis 6 parts, Semen Cassiae 6 parts, Fructus Viticis 4 parts, Semen Cuscutae 4 parts, Fructus Amomi 2 parts, Spica Prunellae 4 parts, Qiang's Radix Angelicae Pubescentis 2 parts, 6 parts, Folium Pini, 7 parts, Folium Mori, Flos Lonicerae 4 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 6 parts, Fructus Leonuri 4 parts, Radix Paeoniae Rubra 4 parts.
Preparation method is prepared into collyrium, is made up of following steps: (1) first by above-mentioned Chinese medicinal material every part by 1g, add water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, stir evenly again adding distil water to 1000 ~ 5000 milliliter and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 0.8 ~ 1.2%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
Pharmacology analysis:
Herba Schizonepetae: acrid in the mouth, slightly warm in nature; Return lung, Liver Channel.Effect is induced sweat loose wind, rash, and disappear skin ulcer; Cure mainly flu, headache, measles, rubella, skin infection from the beginning of.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.Return bladder, liver, spleen channel; Cure mainly affection of exogenous wind-cold; Headache general pain; Joint is ached; Discharging fresh blood stool; Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.
Herba Violae japonicae: taste bitter, acrid, cold.GUIXIN, lung meridian.Have heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling, and the effect of clearing away heat-damp and promoting diuresis, cures mainly furuncle, carbuncle, scrofula, jaundice, dysentery, diarrhoea, conjunctival congestion, sore throat, venom.
Semen Coicis (parched): sweet, be slightly cold, nontoxic.Function spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal; For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Membrana Follicularis ovi: sweet in the mouth, light, property is put down; Return spleen, stomach, lung meridian.Function nourishing YIN and clearing away lung-heat, sore, removing nebula, synthetism; Asthma is coughed, pharyngalgia aphonia, lymphoid tuberculosis, ulcer being unable to heal, the raw cataracta of order, the vertigo, trauma fracture outside curing mainly.
Bai Tongcao: function cures mainly dysuria, gonorrhea, edema, puerpera's galactostasis, blurred vision, nasal obstruction.
Semen Cassiae: bitter in the mouth, sweet and cool in nature, has clearing away liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight.
Fructus Viticis: acrid in the mouth, hardship, cold nature, returns lung, bladder, Liver Channel.Effect dispelling wind and heat pathogens, the clear sharp head, dehumidifying place joint; For headache due to invasion of exogenous pathogens, polarization wind syndrome of head, the order that swoons is dark, the many tear of acute conjunctivitis, pain in order eyeball, gingivitis, arthralgia chiefly caused by damp pathogen contracture.
Semen Cuscutae: acrid-sweet flavor, property is put down, and enters liver, kidney two warp.There is the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antiabortive effect.Can be used for soreness of waist and knee joint, sexual impotence, premature ejaculation, seminal emission, the enuresis, the frequent micturition heeltap, tinnitus, dizziness dim eyesight, visual deterioration, threatened abortion, the inferior disease of band.
Fructus Amomi: warm in nature, acrid in the mouth; Enter spleen, stomach warp; Function cures mainly in circulation of qi promoting tune, and stomach function regulating, is amusing; Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.
Spica Prunellae: pungent, bitter, cold.Return liver, gallbladder meridian.This product bitter cold master enters Liver Channel, and kind removing fire from the liver is with improving eyesight.With controlling flaming up of liver-fire, conjunctival congestion and swelling pain.
Qiang's Radix Angelicae Pubescentis: pungent, bitter, tepor.Return liver, kidney, urinary bladder channel.Function cures mainly expelling wind and dampness, dispersing cold for relieving pain; Cure mainly anemofrigid-damp arthralgia; Lumbocrural pain, few cloudy volt wind headache, headache toothache.Modern pharmacology proves, Radix Angelicae Pubescentis has good analgesia, calmness and antiinflammatory action.
Folium Pini: bitter, puckery, temperature.Function expelling wind and activating blood circulation, improving eyesight, calms the nerves, removing toxic substances, antipruritic; Cure mainly influenza, rheumatic arthritis, treating swelling and pain by traumatic injury, nyctalopia, hypertension, neurasthenia, external treating chilblain.
Folium Mori: be used for the treatment of anemopyretic cold; Pathogenic wind-warm from the beginning of, fever and headache, perspiration and aversion to wind, cough chest pain; Or dryness of the lung dry cough without phlegm; Dry throat and mouth; Wind heat and liver-yang are disturbed; Conjunctival congestion and swelling pain; Can dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing the hyperactive liver improving eyesight, cooling blood for hemostasis.
Flos Lonicerae: cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat effect of wind, cures mainly disease under distension, epidemic febrile disease heating, the diseases such as pyretic toxicity carbuncle and ulcer and tumor.The diseases such as it is dizzy for giddy, xerostomia is done yearningly, hyperhidrosis is unhappy, enteritis, bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, erysipelas, parotitis, suppurative tonsillitis all have certain curative effect.
Radix Scutellariae: bitter in the mouth, cold in nature, enters the heart, lung, gallbladder, large intestine channel; There are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive; Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.Modern pharmacology proves, Radix Scutellariae has the effects such as antibacterial action, antifungic action, antivirus action and antiinflammatory antiallergic action, and does not develop immunity to drugs.
Cortex Phellodendri: bitter in the mouth, cold in nature; Return kidney, bladder, large intestine channel.Function heat clearing away, dampness, pathogenic fire purging, removing toxic substances; Cure mainly hematodiarrhoea, have loose bowels, quench one's thirst, jaundice ， flaccidity of feet with lamenness, nocturnal emission, stranguria with turbid discharge, hemorrhoid, have blood in stool, leucorrhea with red and white discharge, hectic fever due to YIN-deficiency consumptive fever, conjunctival congestion and swelling pain, aphtha of the mouth and tongue, sore swollen toxin.
Fructus Leonuri: acrid in the mouth, hardship, cold nature; GUIXIN bag, Liver Channel.There is the function of promoting blood flow to regulate menstruation, liver heat removing and eyesight improving; Raw Fructus Leonuri is longer than liver heat removing and eyesight improving, for conjunctival congestion and swelling pain or the raw nebula film of order.
Radix Paeoniae Rubra: bitter, is slightly cold; Return Liver Channel; Function clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia abdominal mass is gathered, injury from falling down.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Modern pharmacology research proves, Radix Paeoniae Rubra has antipyretic, antibacterial, spasmolytic, analgesic activity.
The present invention is Chinese medicine preparation sheerly, proves through years of researches and clinical practice: instant effect, cure rate are high, not containing antibiotic, drug safety is reliable, medicine valency is cheap, portably use convenience, avoids toxic and side effects and the anaphylaxis of chemicals.Preparation method is simple and easy to do, easily implements.
Outcome measure:
Recovery from illness: symptom disappears completely, and corpus ciliare redness disappears, ocular foreign bodies sense is eliminated, and conjunctival congestion is disappeared.
Take a turn for the better: symptom disappears substantially, red and swollen and foreign body sensation symptom obviously alleviates.
Invalid: all diseases are without improvement.
Therapeutic outcome: treatment Uveitis Patients 141 example, drip and use medicine of the present invention, first three sky every two hours uses collyrium of the present invention once, uses three every day afterwards.If feel Ocular irritation, have stopping using immediately of allergic symptom, Pregnant and lactant women should be cautious use of.Treat after 2 ~ 4 weeks, recovery from illness 103 example, accounts for 73.0%; Take a turn for the better 37 examples, accounts for 26.2%; Invalid 1 example, accounts for 0.8%.
Attached several routine case is done into an explanation:
Case 1: beam so-and-so, man, 29 years old, because right eye is red, bitterly, is admitted to hospital for blind one week, and companion local is red, pain and headache, and without Nausea and vomiting, be diagnosed as uveitis, use medicine of the present invention to take effect for 2 weeks, within 3 weeks, rear symptom disappears completely.Follow up a case by regular visits to half a year without recurrence.
Case 2: Liu so-and-so, female, 45 years old, patient told eyes and occurs that shadow does not see more than 10 day, is diagnosed as uveitis, used medicine of the present invention 3 weeks symptoms obviously to improve, and after 4 weeks months, symptom disappears completely, followed up a case by regular visits to 1 year without recurrence.
Detailed description of the invention
Embodiment 1:
One treats uveitic Chinese medicine composition, formulated by the raw material of Chinese medicine of following parts by weight: Herba Schizonepetae 4 parts, Radix Saposhnikoviae 4 parts, Herba Violae japonicae 7 parts, Semen Coicis (parched) 4 parts, Membrana Follicularis ovi 8 parts, white Medulla Tetrapanacis 6 parts, Semen Cassiae 6 parts, Fructus Viticis 4 parts, Semen Cuscutae 4 parts, Fructus Amomi 2 parts, Spica Prunellae 4 parts, Qiang's Radix Angelicae Pubescentis 2 parts, 6 parts, Folium Pini, 7 parts, Folium Mori, Flos Lonicerae 4 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 6 parts, Fructus Leonuri 4 parts, Radix Paeoniae Rubra 4 parts.
Preparation method is prepared into collyrium, is made up of following steps: (1) first by above-mentioned Chinese medicinal material every part by 1g, add water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, stir evenly again adding distil water to 3000 milliliter and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 1.0%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
Embodiment 2:
One treats uveitic Chinese medicine composition, formulated by the raw material of Chinese medicine of following parts by weight: Herba Schizonepetae 3 parts, Radix Saposhnikoviae 5 parts, Herba Violae japonicae 5 parts, Semen Coicis (parched) 5 parts, Membrana Follicularis ovi 5 parts, white Medulla Tetrapanacis 8 parts, Semen Cassiae 5 parts, Fructus Viticis 5 parts, Semen Cuscutae 3 parts, Fructus Amomi 3 parts, Spica Prunellae 3 parts, Qiang's Radix Angelicae Pubescentis 3 parts, 5 parts, Folium Pini, 8 parts, Folium Mori, Flos Lonicerae 3 parts, Radix Scutellariae 8 parts, Cortex Phellodendri 5 parts, Fructus Leonuri 5 parts, Radix Paeoniae Rubra 3 parts.
Preparation method is prepared into collyrium, is made up of following steps: (1) first by above-mentioned Chinese medicinal material every part by 1g, add water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, stir evenly again adding distil water to 1000 milliliter and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 0.8%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
Embodiment 3:
One treats uveitic Chinese medicine composition, formulated by the raw material of Chinese medicine of following parts by weight: Herba Schizonepetae 5 parts, Radix Saposhnikoviae 3 parts, Herba Violae japonicae 10 parts, Semen Coicis (parched) 3 parts, Membrana Follicularis ovi 10 parts, white Medulla Tetrapanacis 5 parts, Semen Cassiae 8 parts, Fructus Viticis 3 parts, Semen Cuscutae 5 parts, Fructus Amomi 1 part, Spica Prunellae 5 parts, Qiang's Radix Angelicae Pubescentis 1 part, 8 parts, Folium Pini, 5 parts, Folium Mori, Flos Lonicerae 5 parts, Radix Scutellariae 5 parts, Cortex Phellodendri 8 parts, Fructus Leonuri 3 parts, Radix Paeoniae Rubra 5 parts.
Preparation method is prepared into collyrium, is made up of following steps: (1) first by above-mentioned Chinese medicinal material every part by 1g, add water 5000 milliliters, slow fire boils 1 hour, gets filtrate;
(2) residue adds water 5000 milliliters again, and slow fire boils 1 hour, twice filtrate is merged;
(3) above-mentioned filtrate is concentrated into 125 milliliters, adds the ethanol mixing that 375 milliliters of mass fractions are 95% after cooling, place after 24 hours with filter paper filtering;
(4), after filtrate being waved most or recovery ethanol, stir evenly again adding distil water to 5000 milliliter and obtain medicinal liquid;
(5) adjust medicinal liquid and be equivalent to the osmotic pressure that mass fraction is the sodium chloride of 1.2%, adding preservative agent cyanogen Mercury difluoride. in medicinal liquid, wherein, the volume ratio of cyanogen Mercury difluoride. and medicinal liquid is 1:1500, then adjusts pH value to 7.0 with the sodium hydroxide that mass fraction is 10%;
(6) last medicinal liquid is through filter paper filtering, seals, autoclave sterilization, subpackage 8 mls/branch.
Claims (2)
1. treat a uveitic Chinese medicine composition, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Schizonepetae 3 ~ 5 parts, Radix Saposhnikoviae 3 ~ 5 parts, Herba Violae japonicae 5 ~ 10 parts, Semen Coicis (parched) 3 ~ 5 parts, Membrana Follicularis ovi 5 ~ 10 parts, white Medulla Tetrapanacis 5 ~ 8 parts, Semen Cassiae 5 ~ 8 parts, Fructus Viticis 3 ~ 5 parts, Semen Cuscutae 3 ~ 5 parts, Fructus Amomi 1 ~ 3 part, Spica Prunellae 3 ~ 5 parts, Qiang's Radix Angelicae Pubescentis 1 ~ 3 part, 5 ~ 8 parts, Folium Pini, 5 ~ 8 parts, Folium Mori, Flos Lonicerae 3 ~ 5 parts, Radix Scutellariae 5 ~ 8 parts, Cortex Phellodendri 5 ~ 8 parts, Fructus Leonuri 3 ~ 5 parts, Radix Paeoniae Rubra 3 ~ 5 parts.
2. one as claimed in claim 1 treats uveitic Chinese medicine composition, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: Herba Schizonepetae 4 parts, Radix Saposhnikoviae 4 parts, Herba Violae japonicae 7 parts, Semen Coicis (parched) 4 parts, Membrana Follicularis ovi 8 parts, white Medulla Tetrapanacis 6 parts, Semen Cassiae 6 parts, Fructus Viticis 4 parts, Semen Cuscutae 4 parts, Fructus Amomi 2 parts, Spica Prunellae 4 parts, Qiang's Radix Angelicae Pubescentis 2 parts, 6 parts, Folium Pini, 7 parts, Folium Mori, Flos Lonicerae 4 parts, Radix Scutellariae 6 parts, Cortex Phellodendri 6 parts, Fructus Leonuri 4 parts, Radix Paeoniae Rubra 4 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105168525A (en) * | 2015-09-21 | 2015-12-23 | 江志鑫 | Medicine composition for treating ophthalmologic inflammation and application of medicine composition |
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| CN103055112A (en) * | 2012-11-07 | 2013-04-24 | 山东施尔明眼科医院 | Traditional Chinese medicine compound composition for treating uveitis |
| CN103816356A (en) * | 2012-11-19 | 2014-05-28 | 天津博莱恩科技发展有限公司 | Refined honey syrup for treating uveitis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055112A (en) * | 2012-11-07 | 2013-04-24 | 山东施尔明眼科医院 | Traditional Chinese medicine compound composition for treating uveitis |
| CN103816356A (en) * | 2012-11-19 | 2014-05-28 | 天津博莱恩科技发展有限公司 | Refined honey syrup for treating uveitis |
Non-Patent Citations (1)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105168525A (en) * | 2015-09-21 | 2015-12-23 | 江志鑫 | Medicine composition for treating ophthalmologic inflammation and application of medicine composition |
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Application publication date: 20150506 |