CN1830480A - Medicine for treating myopia and its preparation method - Google Patents
Medicine for treating myopia and its preparation method Download PDFInfo
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- CN1830480A CN1830480A CN 200510031319 CN200510031319A CN1830480A CN 1830480 A CN1830480 A CN 1830480A CN 200510031319 CN200510031319 CN 200510031319 CN 200510031319 A CN200510031319 A CN 200510031319A CN 1830480 A CN1830480 A CN 1830480A
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Abstract
A Chinese medicine in the form of pill, tablet, particle, capsule, or oral liquid for preventing and treating the myopia of juveniles is prepared from pilose asiabell root, wolfberry fruit, Chinese angelica root, tuckahoe and ophiopogon root. Its preparing process is also disclosed.
Description
[technical field]
The present invention relates to a kind of medicine of preventing and treating myopia and preparation method thereof, belong to the field of Chinese medicines.
[background technology]
Myopia is one of modal oculopathy in the world wide, and AAO estimates that global myopia sickness rate is at least 25%, if calculate with this, then global myopia patient never is less than 1,000,000,000.In the area, Asia, our country particularly, bathomorphic sickness rate is higher.2000, the 4th national physique constitution of students investigation shows: China's myopia of student rate is: the pupil 20.23%, and the junior school student 48.18%, and the high school student 71.29%, and the university students 73.01%.Myopia is brought the great inconvenience except giving student learning and life, and high myopic eye also can cause a series of serious ocular complications, is one of main causes of blindness.If can not control effectively, it will have a strong impact on follow-on healthy, even have influence on the raising of nation's quality and china's overall national strength.Therefore, bathomorphic study on prevention is the important topic that people study always.But up to this point, also there are not a kind of therapy and medicine to effect a radical cure myopia from the cause of disease.At present, bathomorphic treatment can be divided into operative therapy and non-operative treatment.Operative therapy mainly contains: surface cornea mirror art, keratomileusis, keratotomy laser, back sclera Reinforcement etc., keratorefractive surgery has solved the mirror problem of wearing of high myopia to a certain extent, also satisfy people's requirements of one's work of being engaged in special occupation, be subjected to myopia patient's welcome.But, operation simple, safety no matter how, also perfectly safe absolutely not, furthermore keratorefractive surgery also is not a very sophisticated operation, many aspects also need to improve and improve, and also exist many complication after the operation simultaneously.Non-operative treatment the best way is to wear glasses, but image appearance is bad, and is also inconvenient, and high myopia is not suitable for.Drug therapy has eye drop and oral formulations, looks granule, vision 1+1 etc. as atropine, melyltropeine, Rhizoma Corydalis Decumbentis, general Shandong tropine, Anisodamine, pilocarpine, compound recipe bendazol, ZHENZHU MINGMUYE and make eye bright mental eye liquid medicine and benefit.Also have some physiotherapys in addition, as acupuncture and moxibustion treatment, the Flos Mume skill of handling needles, ear acupuncture, acusector, low-frequency current method, supercritical ultrasonics technology and laser acupuncture irradiation, but the relief of symptoms that these therapies can only be of short duration, what have also has side effect, influences the physical and mental health of user.Above-mentioned these therapies are having certain effect aspect the treatment of the prevention of myopia and pseudomyopia, but true myopia not have definitely sure curative effect.
[summary of the invention]
In order to overcome the unfavorable shortcoming of existing treatment medicine for treating myopia effect, it is better to the invention provides a kind of therapeutic effect, low price, medicine of control myopia easy to use and preparation method thereof.
Medicament selection Fructus Lycii of the present invention, Radix Codonopsis, Radix Angelicae Sinensis, Radix Ophiopogonis and Poria make up, and make each efficacy of drugs produce synergism these drug regimens, thereby can treat myopia, make eye eyesight recover normal.Wherein select for use Fructus Lycii to be because Fructus Lycii property is sweet, replenishing vital essence to improve eyesight, nourishing the liver and kidney confirms according to pharmacological research: Fructus Lycii has the human central nervous of adjusting, hormonal system, functions of immune system, helps visual deterioration person's recovery.Select for use Radix Codonopsis to be because Radix Codonopsis is sweet flat, go into the spleen lung meridian, invigorating the spleen and replenishing QI belongs to tonic; Radix Angelicae Sinensis, the sweet arduous temperature of property is gone into liver, the heart, spleen channel is enriched blood and is invigorated blood circulation, loosening bowel to relieve constipation, genus limonium medicine; Radix Ophiopogonis, the sweet little bitter cold of property is gone into the heart, lung, and the stomach warp, replenishing YIN and removing heat, nourishing the lung to arrest cough is a YIN-tonifying drug; Poria, property is sweet flat, goes into stomach, kidney channel, heat-clearing and toxic substances removing, spleen invigorating, mind calming is calmed the nerves, and is damp-clearing drug.
In order to reach better curative effect, medicine of the present invention also makes up with Rhizoma Acori Graminei, Fructus Schisandrae Chinensis, Radix Polygalae, Cortex Moutan and Rhizoma Alismatis, and common assistant helps the monarch and his subjects' product blood-activating and qi-promoting, the effect that convergence makes eye bright.This is because the hot temperature of Rhizoma Acori Graminei is gone into the heart, Liver Channel, causing resuscitation with aromatic drugs and in ward off turbid; Fructus Schisandrae Chinensis, property acid temperature is gone into lung, the stomach warp, the sword lung, cloudy now, the smart antidiarrheal of sword is regulated in the nerve and is distinguished; Radix Polygalae, property toil temperature is gone into lung heart kidney channel, the sharp key that eliminates the phlegm, the Fructus Alpiniae Oxyphyllae of calming the nerves; Cortex Moutan, property is arduous to be slightly cold, and goes into conscience stomach warp, clearing away heat and cooling blood, blood circulation promoting competent silt; Rhizoma Alismatis, property is sweet cold, goes into kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen is purged heat.
Medicine each component consumption of the present invention is all to have curative effect preferably in the following weight parts scope:
Fructus Lycii 15-25 part, Radix Codonopsis 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Ophiopogonis 2-6 part and Poria 2-5 part.
Be preferably: 3 parts in 20 parts of Fructus Lycii, 10 parts of Radix Codonopsis, 10 parts of Radix Angelicae Sinensis, 3.6 parts of Radix Ophiopogonis and Poria.
Medicine each component consumption of the present invention can also be: Fructus Lycii 15-25 part, Radix Codonopsis 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Ophiopogonis 2-6 part, Poria 2-5 part, Rhizoma Acori Graminei 1-4 part, Fructus Schisandrae Chinensis 1-4 part, Radix Polygalae 1-4 part, Cortex Moutan 1-5 part and Rhizoma Alismatis 1-5 part.
Be preferably: 2.4 parts of 20 parts of Fructus Lycii, 10 parts of Radix Codonopsis, 10 parts of Radix Angelicae Sinensis, 3.6 parts of Radix Ophiopogonis and 3 parts in Poria, 1.8 parts of Rhizoma Acori Graminei, 1.8 parts of Fructus Schisandrae Chinensis, 1.8 parts of Radix Polygalaes, 2.4 parts of Cortex Moutans and Rhizoma Alismatis.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any routine preparation for oral administration.For example these raw material pulverize mixings can be made powder and take after mixing it with water, or make granule, also can be, concentrate, after the drying and crushing, make tablet or capsule with these crude drug decoctings.
Preferably, the preparation method of medicine of the present invention is as follows:
(1) Radix Codonopsis, Poria, Radix Polygalae and the four kinds of crude drug of Fructus Schisandrae Chinensis with described weight proportion are ground into fine powder, make composition powder 1 after sieving.
(2) Fructus Lycii, Radix Angelicae Sinensis, Radix Ophiopogonis, Rhizoma Acori Graminei, Cortex Moutan and the Rhizoma Alismatis with described weight proportion decocts respectively 2～4 times, and each 60～180 minutes, collecting decoction filtered, and is condensed into thick paste, makes compositions 2
(3) in spissated thick paste compositions 2, add the composition powder 1 that makes, mixing, drying is ground into fine powder, just has been prepared into the active component of medicine of the present invention.
(4) active component of the present invention can add various conventional adjuvant required when preparing different dosage form, prepare any conventional Chinese medicine dosage form as disintegrating agent, lubricant, binding agent etc. with the method for Chinese medicinal of routine, as pill, granule, tablet, capsule, oral liquid etc.
Medicine of the present invention has benefiting vital QI and blood, nourishing the liver and kidney, makes eye bright and calm the nerves, increase the effect of vision.Be used for the treatment of myopia.
[specific embodiment]
One, tests the beneficial effect that further specifies medicine of the present invention below in conjunction with clinical observation.
The clinical observation of Drug therapy myopia of the present invention
1, clinical data
Receive and observe in 180 eyes, 97 of men, 83 eyes of woman.The oldest 20 years old, minimum 11 years old, 15.64 ± 1.87 years old mean age.The course of disease is the longest 5 years, and is the shortest 0.25, average course of disease 1.85 ± 1.29 years old.108 eyes of low myopia, 72 eyes of medium myopia eye.
2, treatment standard: cure: vision rises to more than 1.0; Produce effects: vision rising 3 row, effectively: 2-3 is capable in the vision rising, and is invalid: vision rises less than 2 row or does not have progress.
3, Therapeutic Method:
The capsule of oral medicine of the present invention, every day 3 times, each 2-3 grain, warm water delivery service.30 days is a course of treatment, 2 courses of treatment of logotype.
4, therapeutic outcome:
Accept 180 myopia altogether for medical treatment with medicament capsule of the present invention and suffer from the eye, cure 21, account for 11.7%, effective 117 eyes account for 65.0%, and invalid 42 eyes account for 23.3%, and total effective rate is 76.7%.
Further set forth the preparation method of medicine of the present invention below by embodiment:
The capsule preparation of embodiment 1 medicine of the present invention.
(1) with Radix Codonopsis 100g, Poria 30g, Radix Polygalae 18g, four kinds of crude drug of Fructus Schisandrae Chinensis 18g are ground into fine powder, make compositions 1 after sieving, and are standby.
(2) with Fructus Lycii 200g, Radix Angelicae Sinensis 100g, Radix Ophiopogonis 36g, Rhizoma Acori Graminei 18g, Cortex Moutan 24g, Rhizoma Alismatis 24g decoct respectively 2 times, each 120 minutes, collecting decoction was condensed into thick paste after the filtration, make compositions 2.
(3) in compositions 2, add compositions 1 powder, mixing is also made fine powder, the hard capsule of packing into.Each capsule dress mixing fine powders 0.5 gram.
The preparation tablets of embodiment 2 medicines of the present invention.
(1) take by weighing each crude drug by following weight proportion:
Fructus Lycii 200g, Radix Codonopsis 100g, Radix Angelicae Sinensis 100g, Radix Ophiopogonis 36g, Poria 30g, Rhizoma Alismatis 24g, Cortex Moutan 24g, Rhizoma Acori Graminei 18g, Fructus Schisandrae Chinensis 18g, Radix Polygalae 18g, standby.
(2) Radix Codonopsis, Poria, Radix Polygalae, Fructus Schisandrae Chinensis four flavor crude drug are ground into fine powder, sieve, make compositions fine powder 1.
(3) with other the 6 flavor crude drug beyond the crude drug in (2), decoct respectively 4 times, each 100 minutes, collecting decoction was condensed into thick paste, made compositions 2
(4) merge compositions 1 and compositions 2, add adjuvant and make granule, drying is pressed into tablet, promptly.
Claims (5)
1, a kind of medicine of preventing and treating myopia is characterized in that it mainly is made up of following bulk drugs: Fructus Lycii 15-25 part, Radix Codonopsis 5-15 part, Radix Angelicae Sinensis 5-15 part, Radix Ophiopogonis 2-6 part and Poria 2-5 part.
2, medicine according to claim 1 is characterized in that: wherein the consumption of each material medicine is: 3 parts in 20 parts of Fructus Lycii, 10 parts of Radix Codonopsis, 10 parts of Radix Angelicae Sinensis, 3.6 parts of Radix Ophiopogonis and Poria.
3, medicine according to claim 1 is characterized in that: also have Rhizoma Acori Graminei 1-4 part, Fructus Schisandrae Chinensis 1-4 part, Radix Polygalae 1-4 part, Cortex Moutan 1-5 part and Rhizoma Alismatis 1-5 part in its material medicine.
4, medicine according to claim 3 is characterized in that: wherein the consumption of each component is: 2.4 parts of 20 parts of Fructus Lycii, 10 parts of Radix Codonopsis, 10 parts of Radix Angelicae Sinensis, 3.6 parts of Radix Ophiopogonis and 3 parts in Poria, 1.8 parts of Rhizoma Acori Graminei, 1.8 parts of Fructus Schisandrae Chinensis, 1.8 parts of Radix Polygalaes, 2.4 parts of Cortex Moutans and Rhizoma Alismatis.
5, the preparation method of claim 1 or 4 described medicines is characterized in that: comprise the following steps, extract the active ingredient of medicine earlier, add required conventional adjuvant again, make various Chinese medicine preparation, concrete steps are as follows:
(1) with Radix Codonopsis, Poria, Radix Polygalae and the Fructus Schisandrae Chinensis four flavor raw material of Chinese medicine of described weight proportion, is ground into fine powder, makes compositions 1 after sieving;
(2) Fructus Lycii, Radix Angelicae Sinensis, Radix Ophiopogonis, Rhizoma Acori Graminei, Cortex Moutan and the Rhizoma Alismatis Six-element raw material of Chinese medicine with described weight proportion decocts 2-4 time respectively, and each 60-180 minute, collecting decoction filtered, and is condensed into thick paste, makes compositions 2;
(3) merge resulting composition 1 and compositions 2, mixing, crushed after being dried becomes fine powder, promptly becomes the active ingredient of medicine of the present invention;
(4) active ingredient of the medicine of the present invention that step (3) is made, the conventional adjuvant of adding Chinese medicine preparation as disintegrating agent, lubricant, binding agent, is prepared into different form of Chinese drug, as pill, tablet, granule, capsule, oral liquid, slow releasing agent etc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510031319 CN1830480A (en) | 2005-03-07 | 2005-03-07 | Medicine for treating myopia and its preparation method |
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| CN 200510031319 CN1830480A (en) | 2005-03-07 | 2005-03-07 | Medicine for treating myopia and its preparation method |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194378A (en) * | 2015-10-10 | 2015-12-30 | 刘子辰 | Preparation suitable for middle school students to prevent and treat myopia and preparation method thereof |
| CN105194386A (en) * | 2015-10-10 | 2015-12-30 | 刘子辰 | Liver-nourishing and kidney-tonifying preparation for myopia patients and preparation method |
| CN105287987A (en) * | 2015-12-07 | 2016-02-03 | 黑龙江省智诚医药科技有限公司 | Traditional Chinese medicine dispersible tablets used for treating myopia and preparation method thereof |
| CN106110066A (en) * | 2016-07-30 | 2016-11-16 | 南京正宽医药科技有限公司 | A kind of collyrium |
| CN108126086A (en) * | 2018-01-29 | 2018-06-08 | 张兴科 | A kind of drug for treating myopia and preparation method thereof |
| CN114917299A (en) * | 2022-05-12 | 2022-08-19 | 陕西省中医医院 | Traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and preparation method thereof |
-
2005
- 2005-03-07 CN CN 200510031319 patent/CN1830480A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194378A (en) * | 2015-10-10 | 2015-12-30 | 刘子辰 | Preparation suitable for middle school students to prevent and treat myopia and preparation method thereof |
| CN105194386A (en) * | 2015-10-10 | 2015-12-30 | 刘子辰 | Liver-nourishing and kidney-tonifying preparation for myopia patients and preparation method |
| CN105287987A (en) * | 2015-12-07 | 2016-02-03 | 黑龙江省智诚医药科技有限公司 | Traditional Chinese medicine dispersible tablets used for treating myopia and preparation method thereof |
| CN106110066A (en) * | 2016-07-30 | 2016-11-16 | 南京正宽医药科技有限公司 | A kind of collyrium |
| CN108126086A (en) * | 2018-01-29 | 2018-06-08 | 张兴科 | A kind of drug for treating myopia and preparation method thereof |
| CN114917299A (en) * | 2022-05-12 | 2022-08-19 | 陕西省中医医院 | Traditional Chinese medicine eye applying preparation for treating adolescent accommodation myopia and preparation method thereof |
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