Background
The essential milk is more and more favored by consumers in modern life, and various functional essential milk products are in endless.
CN110840771A discloses a skin-refreshing essence milk, specifically to the technical field of cosmetic preparation, the skin-refreshing essence milk comprises the following raw materials by weight: deionized water, glycerol, propylene glycol, pearl extract, olive oil, hydrolyzed oat protein, angelica rotundifolia root extract, chamomile extract, glyceryl stearate, ceteareth-6, ceteareth-25, shea butter oil, ethylhexyl palmitate, polydimethylsiloxane, cyclomethicone, trehalose, titanium dioxide, nicotinamide, squalane, lecithin, tocopheryl acetate, hyaluronic acid, carbomer, xanthan gum, triethanolamine, allantoin, dipotassium glycyrrhizinate, methylparaben, phenoxyethanol. The product adopts the pearl powder nanotechnology, is added with various natural plant essence stock solutions, has 6 effects of whitening, moisturizing, making up, sun screening, concealing blemishes and nourishing, is simple to prepare, and can replace the traditional BB or CC and sun screen cream for use.
CN109157450A discloses an acne-removing essence milk, which comprises an acne-removing composition a; the acne-removing composition A comprises salvia miltiorrhiza root extract, clove bud extract, scutellaria baicalensis root extract, angelica sinensis root extract, liquorice root extract and centella asiatica extract. According to the acne-removing essence disclosed by the invention, mild plant extract components are added and matched with basic raw materials to prepare the acne-removing essence, so that the water-oil balance of the skin can be adjusted, acnes can be removed, acne marks can be reduced, the damaged skin can be repaired, and the natural health state of the skin can be recovered.
CN111821236A relates to essence milk and a preparation method thereof, which comprises the following steps: oriental cherry flower extract; bisabolol; a Uncaria tomentosa extract; hydrogenated lecithin; glyceryl stearate citrate; polyglyceryl-3 methyl glucose distearate; sodium lauroyl lactylate; a solvent; also relates to a preparation method of the essence milk, which comprises the following steps: step 1, mixing hydrogenated lecithin and a solvent to obtain a first mixture; step 2, mixing glycerol stearate citrate and polyglycerol-3-methyl glucose distearate to obtain a second premix; step 3, uniformly mixing the second premix with the first mixture to obtain a second mixture; step 4, mixing the sodium lauroyl lactylate, the bisabolol and the second mixture to obtain a third mixture; and 5, mixing the cherry blossom extract, the Uncaria tomentosa extract and the third mixture to obtain the essence milk.
People's life rhythm accelerates, people's pressure of living is also increasing along with the increase of age, and more people inevitably appear the wrinkle on the face, this is mainly because the metabolism of skin weakens, and blood circulation is not smooth, and the nutrient substance supply is not enough leads to the accelerated ageing that the free radical level increases and lead to, but simultaneously people also are more and more high to the requirement of self maintenance, consequently, people also more and more pay more attention to the crease-resistance of skin, antisenescence product for people's crease-resistance, antisenescence product's attention is more and more high.
Disclosure of Invention
In order to solve the problems, the invention provides anti-wrinkle and anti-aging essence milk.
The sheep placenta has the most similar structure and components to human placenta, and has good nutritive value. The active substance extracted and purified from the sheep placenta by a scientific method has the main components of micromolecule and skin, has the effects of enhancing the immunity of the organism, resisting aging, resisting tumors and the like, and is widely applied to the fields of medical care, food, cosmetics and the like. Astaxanthin is the natural antioxidant with the strongest antioxidant capacity, and has a special structure, each astaxanthin molecule has two ionone rings, and hydroxyl groups and ketone groups on the rings pass through a cell membrane when protecting the cell membrane, so that the astaxanthin molecules can penetrate through the whole cell membrane structure, but other antioxidants do not have the characteristic. The anti-aging effect of astaxanthin is concerned by more and more researchers, and the anti-aging effect of astaxanthin is reflected in the effects of resisting oxidation, ultraviolet rays and wrinkles, and skin cells are protected from being damaged by adverse factors such as ultraviolet rays. Based on the above thought, the invention provides the anti-wrinkle and anti-aging essence milk.
An anti-wrinkle and anti-aging essence cream, which comprises the following components: a water phase component, an oil phase component and a functional post-addition phase; the water phase components comprise 0.08-0.18% of disodium ethylene diamine tetraacetate, 2.5-5.5% of 1, 3-butanediol, 0.25-0.55% of xanthan gum, 1.5-3.4% of hyaluronic acid and the balance of pure water in parts by mass; the oil phase component comprises 0.8-1.6% of oleyl polyether-3 phosphate, 3.5-6.2% of avocado oil, 1.6-2.4% of cyclopentasiloxane, 1.5-2.4% of emulsifier, 1.5-2.4% of shea butter, 1.5-2.4% of meadowfoam seed oil, 0.35-0.60% of vitamin E acetate and 2.4-3.8% of synergist; the latter components are 1-5% of anti-wrinkle and anti-aging nano microcapsule and 0.1-0.3% of essence.
The anti-wrinkle and anti-aging nano microcapsule is prepared by the following method:
adding 0.55-1.40 parts of sheep placenta dry powder into 8-12 parts of water according to the mass parts, uniformly mixing, adding 0.05-0.18 part of propylene glycol and 0.08-0.24 part of glycerol, uniformly stirring, uniformly mixing, heating to 75-90 ℃, carrying out heat preservation treatment for 10-30min, then adding the mixture, cooling to 50-65 ℃, carrying out heat preservation for 5-20min, then regulating the pH value of the reaction solution to 6.5-8.5 by using a pH value regulator, then adding protease (3000 minus 5500U/g), carrying out heat preservation enzymolysis for 100 minus smash, heating to boiling for inactivation, then regulating the pH value to be neutral, centrifuging, collecting the supernatant, adding 0.2-0.6 part of lecithin and 0.1-0.4 part of dipropylene glycol into 3.5-6.5 parts of supernatant, heating to 65-75 ℃, uniformly mixing, then adding 0.55-0.85 part of astaxanthin oil and 0.8-1.4 part of glycerol, stirring and mixing evenly, and then homogenizing for 20-40min under the pressure of 500-1000bar to obtain the anti-wrinkle anti-aging nano microcapsule.
The preparation method of the synergist comprises the following steps:
according to the mass parts, 10-20 parts of acryloyl dimethyl taurate, 15-22 parts of sulfhydryl polyethylene glycol mercaptopyridine, 2.2-3.5 parts of sodium ethoxide and 0.05-0.2 part of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 70-78 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 2-4 hours, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
The chemical structure of the sulfhydryl polyethylene glycol mercaptopyridine is as follows:
further, the content of the lecithin is 75% -80%.
Further, the emulsifier is lecithin or hydrogenated lecithin.
Further, the pH value regulator is 0.1-0.4mol/L sodium hydroxide solution.
Further, the anti-wrinkle and anti-aging essence milk is prepared from the following components in parts by weight:
1) weighing the water phase components according to the formula, uniformly mixing, heating to boil, and sterilizing for 10-20 min;
2) weighing the oil phase components according to the formula, uniformly mixing, heating to boil, and sterilizing for 10-20 min;
3) respectively and uniformly mixing the two phases, cooling to 60-80 ℃, slowly adding the oil phase component into the water phase component under stirring, homogenizing under the pressure of 100-300bar for 5-15min, cooling to 40-55 ℃, adding the latter components, and continuously homogenizing for 5-10min to obtain the anti-wrinkle and anti-aging essence emulsion.
The reaction mechanism is as follows:
the addition reaction is carried out on acryloyl dimethyl taurate and mercapto polyethylene glycol mercaptopyridine, and the structural formula is shown as follows:
the technical effects are as follows:
according to the invention, sheep placenta dry powder is used as a raw material, an enzyme method is adopted to prepare antioxidant peptide, an enzymolysis product is separated and purified, and then the antioxidant peptide and astaxanthin oil are used as functional active additives to prepare the anti-wrinkle anti-aging nano microcapsule, so that on one hand, the problem of insufficient water solubility of the antioxidant peptide and astaxanthin can be solved by virtue of the microcapsule structure; on the other hand, the stability problem caused by the characteristic that the double bond structure in astaxanthin is highly sensitive to oxygen and heat (is easily oxidized even under room temperature conditions) can also be solved by the microcapsule structure; the anti-wrinkle and anti-aging nano microcapsule can effectively improve the long-term stability and bioavailability of active ingredients and promote the absorption of the active ingredients; the anti-wrinkle and anti-aging essence emulsion can obviously increase the water content of the skin cuticle, reduce the water loss and enhance the skin elasticity; the product of the invention has better skin smoothness, softness and water-moistening feeling than similar products, can obviously lighten skin fine lines and has good anti-wrinkle and anti-aging effects.
Detailed Description
The invention is further illustrated by the following specific examples:
example 1
Adding water phase components 0.08kg of disodium ethylene diamine tetraacetate, 2.5kg of 1, 3-butanediol, 0.25kg of xanthan gum and 1.5kg of hyaluronic acid into 90kg of pure water, uniformly mixing, heating to boil, and sterilizing for 10 min; the oil phase components comprise 0.8kg of oleyl polyether-3 phosphate, 3.5kg of avocado oil, 1.6kg of cyclopentasiloxane, 1.5kg of emulsifier, 1.5kg of shea butter, 1.5kg of white Potentilla seed oil, 0.35kg of vitamin E acetate and 2.4kg of synergist, which are mixed uniformly and heated to boiling for 10min for sterilization; and cooling to 60 ℃ after completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 5min under the pressure of 100bar after adding, then cooling to 40 ℃, adding the subsequent components of 1kg of anti-wrinkle and anti-aging nano-microcapsule and 0.1kg of essence, and continuously homogenizing for 5min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle and anti-aging nano microcapsule is prepared by the following method:
adding 0.55kg of sheep placenta dry powder into 8kg of water, adding 0.05kg of propylene glycol and 0.08kg of glycerin after uniformly mixing, heating to 75 ℃ after uniformly stirring and mixing, carrying out heat preservation treatment for 10min, then adding the mixture, cooling to 50 ℃, carrying out heat preservation for 5min, adjusting the pH value of the reaction solution to 6.5 by using a sodium hydroxide solution, then adding protease (3000U/g), heating to boil and inactivate after carrying out heat preservation and enzymolysis for 100min, then adjusting the pH value to be neutral, centrifuging, collecting the supernatant, adding 0.2kg of lecithin and 0.1kg of dipropylene glycol into 3.5kg of the supernatant, heating to 65 ℃, uniformly mixing and stirring, then adding 0.55kg of astaxanthin oil and 0.8kg of glycerin, uniformly mixing and homogenizing under the pressure of 500bar for 20min, thus obtaining the anti-wrinkle and anti-aging nanocapsule.
The preparation method of the synergist comprises the following steps:
according to the mass kg, 10kg of acryloyl dimethyl taurate, 15kg of sulfhydryl polyethylene glycol mercaptopyridine, 2.2kg of sodium ethoxide and 0.05kg of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 70 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 2 hours, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
Further, the content of the lecithin is 75%.
Further, the emulsifier is lecithin.
Example 2
Adding water phase components 0.14kg of disodium ethylene diamine tetraacetate, 3.5kg of 1, 3-butanediol, 0.45kg of xanthan gum and 2.2kg of hyaluronic acid into 94kg of pure water, mixing uniformly, heating to boil, and sterilizing for 15 min; the oil phase components of 1.2kg of oleyl polyether-3 phosphate, 4.8kg of avocado oil, 1.8kg of cyclopentasiloxane, 2.0kg of emulsifier, 1.9kg of shea butter, 2.0kg of white Potentilla seed oil, 0.48kg of vitamin E acetate and 3.2kg of synergist are mixed uniformly, heated to boiling and sterilized for 15 min; cooling to 70 ℃ after the completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 10min under the pressure of 200bar after the addition, then cooling to 45 ℃, adding the subsequent components of 2kg of anti-wrinkle and anti-aging nano-microcapsule and 0.2kg of essence, and continuously homogenizing for 8min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle and anti-aging nano microcapsule is prepared by the following method:
adding 0.85kg of sheep placenta dry powder into 10kg of water, uniformly mixing, adding 0.12kg of propylene glycol and 0.16kg of glycerin, uniformly stirring, uniformly mixing, heating to 85 ℃, carrying out heat preservation treatment for 20min, then adding, cooling to 55 ℃, carrying out heat preservation for 12min, adjusting the pH value of a reaction solution to 7.5 by using a sodium hydroxide solution, then adding protease (4500U/g), carrying out heat preservation and enzymolysis for 200min, heating to boil and inactivate, then adjusting the pH value to be neutral, centrifuging, collecting a supernatant, adding 0.4kg of lecithin and 0.3kg of dipropylene glycol into 4.5kg of the supernatant, heating to 70 ℃, uniformly mixing and stirring, then adding 0.75 kg of astaxanthin oil and 1.2kg of glycerin, uniformly mixing and uniformly stirring, and homogenizing under the pressure of 800bar for 30min to obtain the anti-wrinkle nano microcapsule.
The preparation method of the synergist comprises the following steps:
according to the mass kg, 12kg of acryloyl dimethyl taurate, 17kg of sulfhydryl polyethylene glycol mercaptopyridine, 2.8kg of sodium ethoxide and 0.1kg of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 75 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 2.5h, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
Further, the content of the lecithin is 78%.
Further, the emulsifier is 8 hydrogenated lecithin.
Example 3
Adding water phase components 0.18kg of disodium ethylene diamine tetraacetate, 5.5kg of 1, 3-butanediol, 0.55kg of xanthan gum and 3.4kg of hyaluronic acid into 96kg of pure water, mixing uniformly, heating to boil, and sterilizing for 20 min; the oil phase components of 1.6kg of oleyl polyether-3 phosphate, 6.2kg of avocado oil, 2.4kg of cyclopentasiloxane, 2.4kg of emulsifier, 2.4kg of shea butter, 2.4kg of white Potentilla seed oil, 0.60kg of vitamin E acetate and 3.8kg of synergist are mixed uniformly, heated to boiling and sterilized for 20 min; and cooling to 80 ℃ after completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 15min under the pressure of 300bar after adding, then cooling to 55 ℃, adding the subsequent components of 5kg of anti-wrinkle and anti-aging nano-microcapsule and 0.3kg of essence, and continuously homogenizing for 10min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle anti-aging nano microcapsule is prepared by the following method:
adding 1.40kg of sheep placenta dry powder into 12kg of water, adding 0.18kg of propylene glycol and 0.24kg of glycerin after uniformly mixing, heating to 90 ℃ after uniformly mixing, carrying out heat preservation treatment for 30min, then adding the mixture, cooling to 65 ℃, carrying out heat preservation for 20min, adjusting the pH value of the reaction solution to 8.5 by using a sodium hydroxide solution, then adding protease (5500U/g), heating to boil and inactivate after carrying out heat preservation and enzymolysis for 300min, then adjusting the pH value to be neutral, centrifuging, collecting the supernatant, adding 0.6kg of lecithin and 0.4kg of dipropylene glycol into 6.5kg of the supernatant, heating to 75 ℃, mixing and uniformly stirring, then adding 0.85kg of astaxanthin oil and 1.4kg of glycerin, uniformly stirring and uniformly mixing, and then homogenizing for 40min under the pressure of 1000bar to obtain the anti-wrinkle and anti-aging nanocapsule.
The preparation method of the synergist comprises the following steps:
according to the mass kg, 20kg of acryloyl dimethyl taurate, 22kg of sulfhydryl polyethylene glycol mercaptopyridine, 3.5kg of sodium ethoxide and 0.2kg of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 78 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 4 hours, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
Further, the content of the lecithin is 80%.
Further, the emulsifier is lecithin.
Comparative example 1
Adding water phase components 0.08kg of disodium ethylene diamine tetraacetate, 2.5kg of 1, 3-butanediol, 0.25kg of xanthan gum and 1.5kg of hyaluronic acid into 90kg of pure water, uniformly mixing, heating to boil, and sterilizing for 10 min; the oil phase components comprise 0.8kg of oleyl polyether-3 phosphate, 3.5kg of avocado oil, 1.6kg of cyclopentasiloxane, 1.5kg of emulsifier, 1.5kg of shea butter, 1.5kg of white Potentilla seed oil, 0.35kg of vitamin E acetate and 2.4kg of synergist, which are mixed uniformly and heated to boiling for 10min for sterilization; cooling to 60 ℃ after completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 5min under the pressure of 100bar after adding, then cooling to 40 ℃, adding the subsequent components of 1kg of anti-wrinkle and anti-aging component and 0.1kg of essence, and continuously homogenizing for 5min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle and anti-aging component is prepared according to the following method:
adding 0.55kg of sheep placenta dry powder into 8kg of water, adding 0.05kg of propylene glycol and 0.08kg of glycerin after uniformly mixing, stirring and uniformly mixing, heating to 75 ℃, carrying out heat preservation treatment for 10min, then adding the mixture, cooling to 50 ℃, carrying out heat preservation for 5min, adjusting the pH value of the reaction solution to 6.5 by using a sodium hydroxide solution, then adding protease (3000U/g), carrying out heat preservation and enzymolysis for 100min, heating to boiling for inactivation, then adjusting the pH value to be neutral, centrifuging, collecting supernatant, adding 0.55kg of astaxanthin oil and 0.8kg of glycerin into 3.5kg of supernatant, and stirring and uniformly mixing to obtain the anti-wrinkle and anti-aging component.
The preparation method of the synergist comprises the following steps:
according to the mass kg, 10kg of acryloyl dimethyl taurate, 15kg of sulfhydryl polyethylene glycol mercaptopyridine, 2.2kg of sodium ethoxide and 0.05kg of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 70 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 2 hours, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
Further, the emulsifier is lecithin.
Comparative example 2
Adding water phase components 0.08kg of disodium ethylene diamine tetraacetate, 2.5kg of 1, 3-butanediol, 0.25kg of xanthan gum and 1.5kg of hyaluronic acid into 90kg of pure water, uniformly mixing, heating to boil, and sterilizing for 10 min; the oil phase components comprise 0.8kg of oleyl polyether-3 phosphate, 3.5kg of avocado oil, 1.5kg of emulsifier, 1.5kg of shea butter, 1.5kg of chinaroot greenbrier seed oil, 0.35kg of vitamin E acetate and 2.4kg of synergist, which are mixed uniformly and heated to boiling, and sterilized for 10 min; and cooling to 60 ℃ after completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 5min under the pressure of 100bar after adding, then cooling to 40 ℃, adding the subsequent components of 1kg of anti-wrinkle and anti-aging nano-microcapsule and 0.1kg of essence, and continuously homogenizing for 5min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle and anti-aging nano microcapsule is prepared by the following method:
adding 0.55kg of sheep placenta dry powder into 8kg of water, adding 0.05kg of propylene glycol and 0.08kg of glycerin after uniformly mixing, heating to 75 ℃ after uniformly stirring and mixing, carrying out heat preservation treatment for 10min, then adding the mixture, cooling to 50 ℃, carrying out heat preservation for 5min, adjusting the pH value of the reaction solution to 6.5 by using a sodium hydroxide solution, then adding protease (3000U/g), heating to boil and inactivate after carrying out heat preservation and enzymolysis for 100min, then adjusting the pH value to be neutral, centrifuging, collecting the supernatant, adding 0.2kg of lecithin and 0.1kg of dipropylene glycol into 3.5kg of the supernatant, heating to 65 ℃, uniformly mixing and stirring, then adding 0.55kg of astaxanthin oil and 0.8kg of glycerin, uniformly mixing and homogenizing under the pressure of 500bar for 20min, thus obtaining the anti-wrinkle and anti-aging nanocapsule.
The preparation method of the synergist comprises the following steps:
according to the mass kg, 10kg of acryloyl dimethyl taurate, 15kg of sulfhydryl polyethylene glycol mercaptopyridine, 2.2kg of sodium ethoxide and 0.05kg of benzoyl peroxide are added into a dry three-neck flask, the reaction temperature is controlled at 70 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 2 hours, and then the vacuum pumping is carried out to remove unreacted materials, so as to obtain the synergist.
Further, the content of the lecithin is 75%.
Further, the emulsifier is lecithin.
Comparative example 3
Adding water phase components 0.08kg of disodium ethylene diamine tetraacetate, 2.5kg of 1, 3-butanediol, 0.25kg of xanthan gum and 1.5kg of hyaluronic acid into 90kg of pure water, mixing uniformly, heating to boil, and sterilizing for 10 min; the oil phase components comprise 0.8kg of oleyl polyether-3 phosphate, 3.5kg of avocado oil, 1.6kg of cyclopentasiloxane, 1.5kg of emulsifier, 1.5kg of shea butter, 1.5kg of white Potentilla seed oil and 0.35kg of vitamin E acetate, uniformly mixing, heating to boil, and sterilizing for 10 min; and cooling to 60 ℃ after completion, slowly adding the oil phase component into the water phase component under stirring, homogenizing for 5min under the pressure of 100bar after adding, then cooling to 40 ℃, adding the subsequent components of 1kg of anti-wrinkle and anti-aging nano-microcapsule and 0.1kg of essence, and continuously homogenizing for 5min to obtain the anti-wrinkle and anti-aging essence emulsion.
The anti-wrinkle and anti-aging nano microcapsule is prepared by the following method:
adding 0.55kg of sheep placenta dry powder into 8kg of water, adding 0.05kg of propylene glycol and 0.08kg of glycerin after uniformly mixing, heating to 75 ℃ after uniformly stirring and mixing, carrying out heat preservation treatment for 10min, then adding the mixture, cooling to 50 ℃, carrying out heat preservation for 5min, adjusting the pH value of the reaction solution to 6.5 by using a sodium hydroxide solution, then adding protease (3000U/g), heating to boil and inactivate after carrying out heat preservation and enzymolysis for 100min, then adjusting the pH value to be neutral, centrifuging, collecting the supernatant, adding 0.2kg of lecithin and 0.1kg of dipropylene glycol into 3.5kg of the supernatant, heating to 65 ℃, uniformly mixing and stirring, then adding 0.55kg of astaxanthin oil, uniformly mixing and stirring, and then homogenizing under the pressure of 500bar for 20min to obtain the anti-wrinkle and anti-aging nano microcapsule.
Further, the content of the lecithin is 75%.
Further, the emulsifier is lecithin.
The centrifugal stability test method of the skin care essence milk prepared by the above examples and comparative examples comprises the following steps: the skin care essence milk is filled into a centrifuge tube and centrifuged for 20min at 1000rpm, and then the particle size and the polydispersity index (PDI) are tested, so that the influence of centrifugation on the system stability is examined.
The statistical results of the stability data of the products of the above examples after centrifugation are as follows:
numbering
|
Particle size (nm)
|
Polydispersity index (PDI)
|
Example 1
|
112
|
0.31
|
Example 2
|
105
|
0.28
|
Example 3
|
88
|
0.23
|
Comparative example 1
|
273
|
0.51
|
Comparative example 2
|
142
|
0.38
|
Comparative example 3
|
367
|
0.73 |