CN114869989A - Traditional Chinese medicine fumigation lotion for treating diabetic foot - Google Patents
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Abstract
The invention relates to a traditional Chinese medicine fumigation lotion for treating diabetic foot, which belongs to the technical field of traditional Chinese medicines and comprises the following raw materials in parts by mass: 10-20 parts of garden balsam, 5-15 parts of radix aconiti agrestis, 5-10 parts of small kusnezoff monkshood root, 10-15 parts of rhizoma anemarrhenae, 15-25 parts of turmeric, 5-10 parts of asafetida, 3-8 parts of ligusticum wallichii, 5-10 parts of momordica grosvenori and 10-15 parts of purslane. In the technical scheme of the invention, the rhizoma anemarrhenae, the turmeric, the perilla, the verbena, the asafetida, the ligusticum wallichii, the momordica grosvenori and the purslane have the effects of oxidation resistance and inflammation diminishing, and the garden balsam: clearing away heat and toxic materials, promoting blood circulation, dispelling blood stasis, relieving swelling, and promoting pus discharge; radix seu herba Tetrastigmatis Hypoglauci: setting bone and promoting granulation, dispelling pathogenic wind and removing dampness, promoting blood circulation and removing obstruction in collaterals; radix aconiti agrestis: clear heat and cool blood, nourish yin and remove toxicity, dissipate blood stasis and alleviate pain.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine fumigation lotion for treating diabetic foot.
Background
The diabetic foot is one of chronic complications of diabetes, ulcer and gangrene are important causes of disability and death of a diabetic patient, one of advanced treatment means is amputation, the pathophysiological change of the diabetic limb ischemia is angiopathy and dysfunction of a nervous system caused by metabolic disorder, the immune function of the diabetic patient is often damaged, the foot infection is easy to occur clinically, even healing difficulties such as ulceration, gangrene and the like occur, amputation is needed by a serious patient, the health of the patient is seriously threatened, and a plurality of foot complications of the diabetic patient are caused by sensory neuropathy and mild autonomic and motor neuropathy. Where sensory neuropathy combined with excessive mechanical stress is a major initiating factor in causing foot ulcers and infections.
In the prior art, antibiotics are selected for local dressing change conventionally, but the wound healing time is long, the pain is obvious, and the pain of a patient is aggravated.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine fumigation lotion for treating diabetic foot, which can realize quick cure of the diabetic foot and has small harm to patients through a traditional Chinese medicine combined preparation of garden balsam, radix aconiti agrestis, rhizoma anemarrhenae, turmeric, ferula asafetida, ligusticum wallichii, momordica grosvenori and purslane.
The technical problems to be solved by the invention are as follows: antibiotics are selected for local dressing change in a conventional method for treating diabetic feet, the wound healing time is long, the pain is obvious, and the pain of a patient is aggravated.
The purpose of the invention can be realized by the following technical scheme:
a traditional Chinese medicine fumigation lotion for treating diabetic foot comprises the following raw materials in parts by mass: 10-20 parts of garden balsam, 5-15 parts of radix aconiti agrestis, 5-10 parts of small kusnezoff monkshood root, 10-15 parts of rhizoma anemarrhenae, 15-25 parts of turmeric, 5-10 parts of asafetida, 3-8 parts of ligusticum wallichii, 5-10 parts of momordica grosvenori and 10-15 parts of purslane.
Further, the feed comprises the following raw materials in parts by mass: 10-18 parts of garden balsam, 5-12 parts of radix aconiti agrestis, 5-9 parts of small kusnezoff monkshood root, 10-14 parts of rhizoma anemarrhenae, 15-20 parts of turmeric, 5-9 parts of asafetida, 3-7 parts of ligusticum wallichii, 5-8 parts of momordica grosvenori and 10-15 parts of purslane.
Further, the feed comprises the following raw materials in parts by mass: 12-18 parts of garden balsam, 7-12 parts of radix aconiti agrestis, 6-9 parts of small kusnezoff monkshood root, 11-14 parts of rhizoma anemarrhenae, 17-20 parts of turmeric, 6-9 parts of asafetida, 4-7 parts of ligusticum wallichii, 6-8 parts of momordica grosvenori and 12-15 parts of purslane.
Further, the preparation method of the traditional Chinese medicine fumigation lotion for treating diabetic foot comprises the following steps:
weighing the raw materials in parts by mass, putting the traditional Chinese medicines into water for decoction, filtering to obtain primary filter residue and primary filtrate, putting the primary filter residue into water for decoction, filtering to obtain secondary filter residue and secondary filtrate, and combining the primary filtrate and the secondary filtrate to obtain the traditional Chinese medicine fumigation lotion for treating diabetic foot.
Further, the Chinese medicine is put into water for decocting for 1-2 h.
Further, the decoction temperature of the Chinese medicinal materials in water is 90-95 deg.C.
Further, the time for decocting the primary filter residue in water is 30 min.
Further, after the primary filtrate and the secondary filtrate are combined, the temperature of the liquid medicine is kept between 45 and 50 ℃.
The invention has the beneficial effects that:
in the technical scheme of the invention, the used traditional Chinese medicine mainly has the following advantages:
the rhizoma anemarrhenae contains mango sweet which is a polyphenol and is antioxidant through ROS inhibition and anti-inflammatory action;
turmeric contains a large amount of curcumin, which is a polyphenol and has antioxidant and anti-inflammatory properties beneficial to wound healing applications;
the perilla and verbena contain apigenin, and the apigenin has the characteristics of oxidation resistance and antibiosis and has good curative effect on wound healing;
the resina Ferulae and rhizoma Ligustici Chuanxiong contain a large amount of ferulic acid, have anti-inflammatory and antioxidant effects on wound, and can promote wound healing;
fructus Siraitiae Grosvenorii and herba Portulacae contain vitamin C, has antioxidant and anti-apoptosis effects, and can promote wound healing, epidermal and dermal development, collagen production, and reduce apoptosis;
impatiens chinensis: clearing away heat and toxic materials, promoting blood circulation, dispelling blood stasis, relieving swelling, and promoting pus discharge;
radix seu herba Tetrastigmatis Hypoglauci: setting bone and promoting granulation, dispelling pathogenic wind and removing dampness, promoting blood circulation and removing obstruction in collaterals;
radix aconiti agrestis: clear heat and cool blood, nourish yin and remove toxicity, dissipate blood stasis and alleviate pain.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine fumigation lotion for treating diabetic foot comprises the following raw materials in parts by mass: 12 parts of garden balsam, 7 parts of radix aconiti agrestis, 6 parts of small kusnezoff monkshood root, 11 parts of rhizoma anemarrhenae, 17 parts of turmeric, 6 parts of asafetida, 4 parts of ligusticum wallichii, 6 parts of momordica grosvenori and 12 parts of purslane;
weighing the raw materials in parts by mass, putting the traditional Chinese medicines into water, decocting for 1h at 90 ℃, filtering to obtain primary filter residue and primary filtrate, putting the primary filter residue into water, decocting for 30min, filtering to obtain secondary filter residue and secondary filtrate, mixing the primary filtrate and the secondary filtrate, and keeping the temperature of the liquid medicine at 45 ℃ to obtain the traditional Chinese medicine fumigation lotion for treating diabetic foot.
Example 2
A traditional Chinese medicine fumigation lotion for treating diabetic foot comprises the following raw materials in parts by mass: 16 parts of garden balsam, 10 parts of radix aconiti agrestis, 8 parts of small kusnezoff monkshood root, 12 parts of rhizoma anemarrhenae, 18 parts of turmeric, 8 parts of asafetida, 6 parts of ligusticum wallichii, 7 parts of momordica grosvenori and 13 parts of purslane;
weighing the raw materials in parts by mass, putting the traditional Chinese medicines into water, decocting at 92 ℃ for 1.5h, filtering to obtain primary filter residue and primary filtrate, putting the primary filter residue into water, decocting for 30min, filtering to obtain secondary filter residue and secondary filtrate, mixing the primary filtrate and the secondary filtrate, and keeping the temperature of the liquid medicine at 47 ℃ to obtain the traditional Chinese medicine fumigation lotion for treating diabetic foot.
Example 3
A traditional Chinese medicine fumigation lotion for treating diabetic foot comprises the following raw materials in parts by mass: 18 parts of garden balsam, 12 parts of Japanese ardisia herb, 9 parts of small kusnezoff monkshood root, 14 parts of common anemarrhena rhizome, 20 parts of turmeric, 9 parts of Chinese asafetida, 7 parts of szechuan lovage rhizome, 8 parts of grosvenor momordica fruit and 15 parts of purslane;
weighing the raw materials in parts by mass, putting the traditional Chinese medicines into water, decocting at 95 ℃ for 2h, filtering to obtain primary filter residue and primary filtrate, putting the primary filter residue into water, decocting for 30min, filtering to obtain secondary filter residue and secondary filtrate, mixing the primary filtrate and the secondary filtrate, and keeping the temperature of the liquid medicine at 50 ℃ to obtain the traditional Chinese medicine fumigation lotion for treating diabetic foot.
The traditional Chinese medicine fumigation lotion for treating diabetic foot prepared in example 2 was now tested:
200 diabetic foot patients were randomized into treatment and control groups of 100 patients each. Treatment groups: 45 men and 55 women, age 47-66, mean (56.2 ± 2.65) years. Control group: 48 men and 52 women, age 42-68 years, mean (57.5 ± 3.47) years. The average course of disease is treated statistically, the difference is not statistically significant (P >0.05), and the injection is comparable, the control group intravenous injection is 20ml daily, and the two groups are 20 days as a treatment course, and two treatment courses are continuously used.
The evaluation standard of the curative effect refers to the Chinese traditional medicine disease diagnosis curative effect standard in 1992. And (3) healing: the pain, numbness, coolness and other symptoms disappear after treatment, and the skin color returns to normal; the effect is shown: the symptoms of pain, numbness, coolness and the like are obviously improved after treatment, and the skin color is obviously improved; the method has the following advantages: the symptoms of pain, numbness, coolness and the like are improved after treatment, and the skin color is improved; and (4) invalidation: the symptoms of pain, numbness, coolness and the like are not obviously changed or worsened after treatment, the skin color is not changed, and the test results are shown in the following table 1.
TABLE 1
As can be seen from table 1 above, the traditional Chinese medicine fumigation lotion for treating diabetic foot prepared in the embodiment of the present invention has better therapeutic effect than the comparative example.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.
Claims (8)
1. A traditional Chinese medicine fumigation lotion for treating diabetic foot is characterized in that: the composite material comprises the following raw materials in parts by mass: 10-20 parts of garden balsam, 5-15 parts of radix aconiti agrestis, 5-10 parts of small kusnezoff monkshood root, 10-15 parts of rhizoma anemarrhenae, 15-25 parts of turmeric, 5-10 parts of asafetida, 3-8 parts of ligusticum wallichii, 5-10 parts of momordica grosvenori and 10-15 parts of purslane.
2. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 1, characterized in that: the composite material comprises the following raw materials in parts by mass: 10-18 parts of impatiens balsamina, 5-12 parts of radix aconiti agrestis, 5-9 parts of small kusnezoff monkshood root, 10-14 parts of rhizoma anemarrhenae, 15-20 parts of turmeric, 5-9 parts of asafetida, 3-7 parts of ligusticum wallichii, 5-8 parts of momordica grosvenori and 10-15 parts of purslane.
3. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 1, characterized in that: the composite material comprises the following raw materials in parts by mass: 12-18 parts of garden balsam, 7-12 parts of radix aconiti agrestis, 6-9 parts of small kusnezoff monkshood root, 11-14 parts of rhizoma anemarrhenae, 17-20 parts of turmeric, 6-9 parts of asafetida, 4-7 parts of ligusticum wallichii, 6-8 parts of momordica grosvenori and 12-15 parts of purslane.
4. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 3, characterized in that: the preparation method comprises the following steps:
weighing the raw materials in parts by mass, putting the traditional Chinese medicines into water for decoction, filtering to obtain primary filter residue and primary filtrate, putting the primary filter residue into water for decoction, filtering to obtain secondary filter residue and secondary filtrate, and combining the primary filtrate and the secondary filtrate to obtain the traditional Chinese medicine fumigation lotion for treating diabetic foot.
5. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 4, characterized in that: decocting the Chinese medicinal materials in water for 1-2 hr.
6. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 4, characterized in that: decocting the Chinese medicinal materials in water at 90-95 deg.C.
7. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 4, characterized in that: decocting the primary residue in water for 30 min.
8. The traditional Chinese medicine fumigation lotion for treating diabetic foot according to claim 4, characterized in that: mixing the primary filtrate and the secondary filtrate, and keeping the temperature of the liquid medicine at 45-50 ℃.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263549A (en) * | 2013-05-21 | 2013-08-28 | 王玉亮 | Chinese medicine fumigating and washing agent for treating diabetic feet |
| CN105663688A (en) * | 2016-03-01 | 2016-06-15 | 张俊然 | Traditional Chinese medicine fumigant for treating diabetic foot |
| CN106344850A (en) * | 2016-11-04 | 2017-01-25 | 盛芳 | Traditional Chinese medicine composition for treating diabetic foot |
| CN106474444A (en) * | 2016-11-29 | 2017-03-08 | 佛山健翔医院有限公司 | A kind of external application Chinese medicine medicated bag formula, medicated bag and its using method |
| CN109420128A (en) * | 2017-08-20 | 2019-03-05 | 梁肆生 | A kind of external application Chinese medicine pack formula, pack and its application method |
-
2022
- 2022-05-27 CN CN202210589825.6A patent/CN114869989A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103263549A (en) * | 2013-05-21 | 2013-08-28 | 王玉亮 | Chinese medicine fumigating and washing agent for treating diabetic feet |
| CN105663688A (en) * | 2016-03-01 | 2016-06-15 | 张俊然 | Traditional Chinese medicine fumigant for treating diabetic foot |
| CN106344850A (en) * | 2016-11-04 | 2017-01-25 | 盛芳 | Traditional Chinese medicine composition for treating diabetic foot |
| CN106474444A (en) * | 2016-11-29 | 2017-03-08 | 佛山健翔医院有限公司 | A kind of external application Chinese medicine medicated bag formula, medicated bag and its using method |
| CN109420128A (en) * | 2017-08-20 | 2019-03-05 | 梁肆生 | A kind of external application Chinese medicine pack formula, pack and its application method |
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