CN114869946B - Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof - Google Patents
Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof Download PDFInfo
- Publication number
- CN114869946B CN114869946B CN202210685010.8A CN202210685010A CN114869946B CN 114869946 B CN114869946 B CN 114869946B CN 202210685010 A CN202210685010 A CN 202210685010A CN 114869946 B CN114869946 B CN 114869946B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- traditional chinese
- parts
- portions
- paste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/235—Foeniculum (fennel)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a traditional Chinese medicine wax moxibustion phase change paste and a preparation and use method thereof, wherein the raw materials comprise: medical paraffin, medical vaseline and various traditional Chinese medicine powder. The melting point, hardness and cohesiveness of the traditional Chinese medicine wax moxibustion phase change paste are adjusted by adding the medical vaseline, the risk of low-temperature scalding is reduced, the use safety is improved, and compared with the traditional wax moxibustion paste, the traditional Chinese medicine wax moxibustion phase change paste has the effects of softness, no separation, hardness and no dispersion, the plasticity of the traditional Chinese medicine wax moxibustion phase change paste is improved, the fit with a human body is improved, the medicine uniformity of the phase change paste is improved, and the phase change paste is more convenient to reuse; the angelica dahurica component is added, the problem of greasy skin existing in the existing wax moxibustion ointment is solved, and the use experience of the traditional Chinese medicine wax moxibustion phase change ointment is greatly improved.
Description
Technical Field
The invention belongs to the field of external use of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine wax moxibustion phase change paste and a preparation and use method thereof.
Background
The Chinese medicinal wax moxibustion ointment is a practical external treatment technology of Chinese traditional medicine which is combined with the traditional Chinese medicine and the modern medical technology after wax therapy and medicinal moxibustion, and achieves the effects of warming channels, dispelling cold, promoting blood circulation, relieving pain, dispelling wind and removing dampness by applying the Chinese medicinal ointment to affected parts or acupuncture points of human bodies and utilizing the medicinal effect of the Chinese traditional medicine and the heat conduction and mechanical effect of the wax therapy.
The common wax therapy is made of medical paraffin, has only heat conduction and mechanical pressure effects, cannot realize the unique effects of the traditional Chinese medicine, is crisp and fragile in texture, and is not easy to be applied to the concave-convex joint surface; the traditional Chinese medicine moxibustion has good permeation effect, but has low heat capacity, large heat conductivity coefficient, high temperature accuracy requirement in operation, easy scald initiation, difficult smearing and easy dry cracking in use.
The inventor tries the traditional Chinese medicine wax moxibustion ointment on the market, and discovers that the following problems exist: the existing traditional Chinese medicine wax moxibustion ointment usually directly uses paraffin as a phase change material, but the phase change temperature of the paraffin exceeds 45 ℃, and long-term sticking of the paraffin to human skin can increase the risk of low-temperature scalding, so that the melting point of the traditional Chinese medicine wax moxibustion ointment needs to be adjusted. In addition, when the conventional paraffin-based moxibustion cream is used, the inventor finds that the conventional paraffin-based moxibustion cream is not strong in cohesiveness when peeled off from human skin after being used, and the powder and the paraffin are easy to separate (hard and loose), so that the skin is polluted by some traditional Chinese medicine fine powder and the paraffin, and the powder and the paraffin are easy to separate (soft and separate) when being heated and melted, and the powder and the paraffin are required to be fully stirred in condensation to be uniformly mixed again, so that the conventional paraffin-based moxibustion cream is very troublesome to operate when being repeatedly used. In addition, after the skin is peeled off after the traditional wax moxibustion cream is used, the greasy feeling of the skin is reflected by a patient to be stronger, which indicates that the residual low-melting-point wax oil on the skin is more.
Disclosure of Invention
Aiming at the defects and drawbacks existing in the prior art, the invention provides a traditional Chinese medicine wax moxibustion phase-change paste with a phase-change temperature of 40-45 ℃ and a preparation and use method thereof, and the phase-change paste is mainly compounded by using medical paraffin and medical vaseline in proportion so as to achieve the purpose of reducing the melting point of the traditional Chinese medicine wax moxibustion phase-change paste.
In order to solve the technical problems, the invention provides the following technical scheme:
the traditional Chinese medicine wax moxibustion phase change paste is characterized by comprising medical paraffin, medical vaseline and traditional Chinese medicine fine powder.
Preferably, the phase change paste for wax moxibustion comprises 450-520 parts of medical paraffin, 40-70 parts of medical vaseline and 200-300 parts of traditional Chinese medicine fine powder, wherein each part of traditional Chinese medicine fine powder comprises 10-20 parts of radix angelicae pubescentis, 25-30 parts of mistletoe, 10-20 parts of eucommia ulmoides, 15-25 parts of radix cyathulae, 8-12 parts of frankincense, 8-14 parts of myrrh, 25-30 parts of rheum officinale, 3-8 parts of pericarpium zanthoxyli, 3-6 parts of borneol, 4-5 parts of fennel, 8-10 parts of green tangerine peel, 10-15 parts of rhizoma corydalis, 15-20 parts of ground beetle, 25-35 parts of lycopodium clavatum, 20-35 parts of suberect spatholobus stem and 5-10 parts of radix angelicae.
In addition, the invention also provides a preparation method of the traditional Chinese medicine wax moxibustion phase change paste, which is characterized by comprising the following steps:
(1) According to the weight parts of the traditional Chinese medicine fine powder, the traditional Chinese medicine fine powder comprises 10-20 parts of radix angelicae pubescentis, 25-30 parts of mistletoe, 10-20 parts of eucommia ulmoides, 15-25 parts of medicinal cyathula root, 8-12 parts of frankincense, 8-14 parts of myrrh, 25-30 parts of rheum officinale, 3-8 parts of pericarpium zanthoxyli, 3-6 parts of borneol, 4-5 parts of fennel, 8-10 parts of green tangerine peel, 10-15 parts of rhizoma corydalis, 15-20 parts of ground beetle, 25-35 parts of lycopodium clavatum, 20-35 parts of suberect spatholobus stem and 5-10 parts of angelica dahurica, and is crushed into 200 mesh fine powder after being weighed, uniformly mixed for standby;
(2) And (2) adding 450-520 parts of medical paraffin, 40-70 parts of medical vaseline and 200-300 parts of traditional Chinese medicine fine powder according to the weight ratio, heating and melting the medical paraffin to be liquid, adding the medical vaseline, continuously stirring until the medical paraffin is completely melted and uniformly mixed, adding the traditional Chinese medicine fine powder prepared in advance in the step (1), uniformly stirring, continuously heating until the traditional Chinese medicine fine powder is completely melted to be thin paste, pouring the thin paste into a clean container with a cover, and sealing and storing at normal temperature.
Preferably, the clean container with cover can be a transparent cutlery box made of polypropylene.
In addition, the invention also provides a use method of the traditional Chinese medicine wax moxibustion phase change paste, which is characterized by comprising the following steps:
1) Putting the traditional Chinese medicine wax moxibustion phase change paste into a microwave oven, and heating for 5 minutes to melt the phase change paste again into flowable thin paste;
2) Slowly pouring the thin pasty traditional Chinese medicine wax moxibustion phase-change paste obtained in the step 1) on a preservative film, automatically spreading the thin pasty traditional Chinese medicine wax moxibustion phase-change paste into a pancake shape, standing and cooling, covering a layer of mulberry paper after the surface of the thin pasty traditional Chinese medicine wax moxibustion phase-change paste loses luster and does not flow, and then attaching one side of the traditional Chinese medicine wax moxibustion phase-change paste mulberry paper to the skin of a certain part of a human body;
3) Then covering clothes or applying a heat preservation bag on the preservative film, and removing the traditional Chinese medicine wax moxibustion phase change paste after the heat of a human body is felt to be eliminated, wherein the traditional Chinese medicine wax moxibustion phase change paste is hardened into a pancake which is fit with the curve of the human body part;
4) Cutting the traditional Chinese medicine wax moxibustion phase change paste obtained in the step 3) into small blocks, placing the small blocks into a clean container with a cover, sealing and preserving at normal temperature, and waiting for the next use.
Preferably, the phase change paste for wax moxibustion of traditional Chinese medicine can be reused for at most 10 times.
In the invention, the medical paraffin has large heat capacity and small heat conductivity, and is not suitable for scalding; slow heat dissipation, strong heat preservation capability and continuous effect of improving blood circulation; has plasticity and viscosity, and can exert mechanical compression on the treatment part during cooling and solidification, promote edema absorption, and facilitate heat transfer to deep tissue, soften scar and connective tissue adhesion.
According to the invention, the medical vaseline has small skin irritation, and the traditional Chinese medicine wax moxibustion phase-change paste can be added to soften the traditional Chinese medicine wax moxibustion phase-change paste, so that the traditional Chinese medicine wax moxibustion phase-change paste can be soft and not separated (when the traditional Chinese medicine wax moxibustion phase-change paste is melted and softened, the medicinal powder, the medical paraffin and the medical vaseline are uniformly mixed, and no gravity delamination occurs), and is hard and not scattered (when the medical vaseline is cooled and solidified and hardened, the whole paste has good molding plasticity, and no fracture and cracking and debris contamination occur), and can prevent the traditional Chinese medicine wax moxibustion phase-change paste from generating low-temperature scalding to the skin when the traditional Chinese medicine wax moxibustion phase-change paste is used for a long time, and avoid irreversible damage to the skin. Experimental data show that the melting point range of the traditional Chinese medicine wax moxibustion phase change paste can be effectively reduced to 40-45 ℃ by adopting the component proportion of the traditional Chinese medicine paraffin and the medical vaseline.
Herba Taxilli and cortex Eucommiae in the fine powder can strengthen tendons and bones; radix Angelicae Pubescentis, pericarpium Citri Reticulatae viride, rhizoma corydalis, herba Lycopodii, and Olibanum can dredge collaterals and relieve pain; radix Cyathulae, radix et rhizoma Rhei, myrrha, eupolyphaga Seu Steleophaga, and caulis Spatholobi can promote blood circulation and remove blood stasis; the fructus zanthoxyli, the borneol and the fennel can dispel cold and relieve pain, have aromatic substances, can promote the comprehensive effect of the permeable traditional Chinese medicine fine powder of the active ingredients of the traditional Chinese medicine, can obviously improve the blood circulation state of a human body and prevent diseases; meanwhile, the traditional Chinese medicine composition has the effects of strengthening tendons and bones, warming channels, dredging collaterals, activating blood circulation, removing blood stasis, dispelling cold and relieving pain, and can effectively improve uncomfortable symptoms of diseases such as cervical spondylosis, lumbar disc herniation, knee osteoarthritis, scapulohumeral periarthritis, mastitis, chronic prostatitis, pelvic effusion and the like. The Chinese medicinal fine powder comprises Chinese taxillus herb, lignans and flavonoids of eucommia ulmoides, phenylpropanoids of radix angelicae pubescentis, volatile oils and flavonoids of green tangerine peel, various alkaloids of rhizoma corydalis and lycopodium clavatum, volatile oils of frankincense and myrrh, sterols of medicinal cyathula root, anthraquinones of rheum officinale, n-hexane and n-butanol of ground beetle and flavonoids of suberect spatholobus stem which are taken as main active ingredients, and can play roles in promoting blood circulation, resisting bacteria, diminishing inflammation, easing pain and promoting organism immunity.
The radix angelicae powder has the viscosity and adsorptivity similar to those of flour, so that the cohesiveness of the traditional Chinese medicine wax moxibustion phase-change paste can be increased, the adsorption effect on low-melting-point oily substances in medical paraffin and medical vaseline is increased, and the precipitation of the low-melting-point oily substances in the medical paraffin and the medical vaseline is reduced, so that the technical effect of adhesion and non-staining is realized, namely, the traditional Chinese medicine wax moxibustion phase-change paste can be separated from skin after being used, the residual quantity of wax oil is reduced, the skin of a human body is not stained, and the greasy feeling of the traditional Chinese medicine wax moxibustion phase-change paste to the skin is reduced.
Compared with the prior art, the invention has the following beneficial effects:
(1) The external traditional Chinese medicine wax moxibustion phase change paste disclosed by the invention is added with a plurality of traditional Chinese medicines, can realize the unique functions of activating blood circulation to remove blood stasis, regulating qi movement, strengthening tendons and bones, dredging collaterals and relieving pain, and has the advantages of good curative effect, quick response, safety and no side effect; the medical paraffin is added, so that the heat dissipation is slow, the heat preservation capability is strong, the medicine absorption can be accelerated, the transfer of medicine components to deep tissues by means of heat is facilitated, the scar and connective tissue adhesion are softened, and the blood circulation is continuously improved;
(2) The traditional Chinese medicine wax moxibustion phase-change paste is soft and not layered (namely, when melted and softened, the traditional Chinese medicine wax moxibustion phase-change paste is uniformly mixed with the paraffin and the vaseline, and gravity layering does not occur, and the layering of the medicine components and the matrix does not occur when solidified, so that the reduction of the effect of medicine components due to heat permeation can be avoided, and through repeated experiments, the traditional Chinese medicine fine powder has the key effect of solving the problem of uniform mixing of the medicine powder and the matrix, is hard and not scattered (namely, when cooled and solidified and hardened, the molding plasticity of the whole paste is good, and fracture and cracking do not occur), thereby avoiding the defects of premature reduction of uniformity and easy reduction of the shaping property and paste dispersion occurring when the traditional Chinese medicine wax moxibustion phase-change paste is repeatedly used, and further improving the repeated use times of the traditional Chinese medicine wax moxibustion phase-change paste. Test results show that the traditional Chinese medicine wax moxibustion phase change paste can be stably and repeatedly used for 10 times.
(3) Through the compounding of medical paraffin and medical Vaseline, the phase change melting point of single medical paraffin-based wax moxibustion ointment is reduced, and the material ratio used in the application can enable the overall melting point of the traditional Chinese medicine wax moxibustion phase change ointment to be reduced to the range of 40-45 ℃ from the vicinity of 53 ℃, so that the phenomenon of low-temperature scalding caused by long-time contact of human skin with materials higher than 45 ℃ is avoided, and the use safety of the traditional Chinese medicine wax moxibustion phase change ointment is greatly improved.
(4) The radix angelicae powder has the viscosity and adsorptivity similar to those of flour, so that the cohesiveness of the traditional Chinese medicine wax moxibustion phase-change paste can be increased, the adsorption effect on low-melting-point oily substances in medical paraffin and medical vaseline is increased, and the precipitation of part of low-melting-point wax oil in the cooling process is reduced, so that the technical effect of adhesion and non-staining is realized, namely, the wax oil residue on the surface of the skin is reduced when the traditional Chinese medicine wax moxibustion phase-change paste is separated from the skin after the traditional Chinese medicine wax moxibustion phase-change paste is used, and the skin is not stained, so that the greasy feeling of the skin is easily caused after the traditional Chinese medicine wax moxibustion phase-change paste is used is reduced.
Drawings
Fig. 1 Chinese medicinal wax moxibustion phase change paste product
FIG. 2 is a flow chart for preparing phase-change paste by wax moxibustion
FIG. 3 is a flow chart of the use of the phase change paste for wax moxibustion
Detailed Description
Example 1
A Chinese medicinal wax moxibustion phase change paste comprises the following components: 450g of medical paraffin, 40g of medical vaseline, 16g of radix angelicae pubescentis, 25g of Chinese taxillus twig, 10g of eucommia ulmoides, 15g of medicinal cyathula root, 8g of frankincense, 8g of myrrh, 25g of rheum officinale, 3g of pericarpium zanthoxyli, 3g of borneol, 4g of fennel, 8g of green tangerine peel, 10g of rhizoma corydalis, 15g of ground beetle, 25g of lycopodium clavatum, 20g of suberect spatholobus stem and 5g of radix angelicae.
The preparation method of the traditional Chinese medicine wax moxibustion phase change paste comprises the following steps:
(1) Weighing 16g of radix angelicae pubescentis, 25g of mistletoe, 10g of eucommia ulmoides, 15g of medicinal cyathula root, 8g of frankincense, 8g of myrrh, 25g of rheum officinale, 3g of pericarpium zanthoxyli, 3g of borneol, 4g of fennel, 8g of green tangerine peel, 10g of rhizoma corydalis, 15g of ground beetle, 25g of lycopodium clavatum, 20g of suberect spatholobus stem and 5g of radix angelicae, 200g in total, crushing the medicaments into 200-mesh fine powder, and uniformly mixing for later use; then weighing 450g of medical paraffin and 40g of medical vaseline;
(2) Placing the medical paraffin in the step (1) into a stainless steel container, heating the medical paraffin in a water bath to melt the medical paraffin into a liquid state, adding the medical vaseline in the step (1), continuously stirring the medical vaseline until the medical vaseline is completely melted and uniformly mixed, adding the traditional Chinese medicine fine powder prepared in the step (1) in advance, uniformly stirring the traditional Chinese medicine fine powder, continuously heating the traditional Chinese medicine fine powder in a water bath until the traditional Chinese medicine fine powder is completely melted into a thin paste state, pouring the thin paste into a transparent cutlery box made of polypropylene, and sealing the transparent cutlery box for normal-temperature storage.
The application method of the traditional Chinese medicine wax moxibustion phase change paste comprises the following steps:
(1) The container which is stored at normal temperature and is filled with the traditional Chinese medicine wax moxibustion phase change paste is opened, the container is put into a microwave oven and heated for 5 minutes, so that the container is melted again into a flowable thin paste;
(2) Slowly pouring the thin pasty traditional Chinese medicine wax moxibustion phase-change paste obtained in the step (1) on a preservative film, automatically spreading the thin pasty traditional Chinese medicine wax moxibustion phase-change paste into a pancake shape, standing and cooling, covering a layer of mulberry paper after the surface of the thin pasty traditional Chinese medicine wax moxibustion phase-change paste loses luster and does not flow, and then attaching one side of the traditional Chinese medicine wax moxibustion phase-change paste mulberry paper to the skin of a certain part of a human body;
(3) Then covering clothes or applying a heat preservation bag by the preservative film, and removing the traditional Chinese medicine wax moxibustion phase change paste after the heat of a human body is felt to be eliminated, wherein the traditional Chinese medicine wax moxibustion phase change paste is hardened into a thin cake which is fit with the curve of the human body part;
(4) Cutting the traditional Chinese medicine wax moxibustion phase change paste obtained in the step (3) into small blocks, placing the small blocks into a clean container with a cover, sealing and preserving at normal temperature, and waiting for the next use.
The melting point of the wax moxibustion paste of example 1 was determined as follows:
the traditional Chinese medicine wax moxibustion phase-change paste prepared in the embodiment 1 and the box body are directly placed into a microwave oven to be heated, the traditional Chinese medicine wax moxibustion phase-change paste is taken out after being changed into liquid about 5 minutes, a thermometer (measuring range of 0-100 ℃) is rapidly placed into the liquid wax moxibustion paste, temperature readings are recorded every 20 seconds, and descending data of temperature change along with time are obtained, so that the melting point of the wax moxibustion paste in the embodiment 1 is 42.4 ℃, and the melting point is shown in the table 1.
Examples 2 to 6
Examples 2 to 6 differ from example 1 in the specific amounts of the medical paraffin, the medical vaseline and the fine powder of the Chinese medicine used, which differ from example 1.
Comparative examples 1 to 6
Comparative examples 1 and 2 were prepared by weighing 100g of medical paraffin and 100g of medical vaseline, respectively, and measuring the melting point; comparative example 3 is a combination of 450g of medical paraffin and 200g of fine powder of traditional Chinese medicine; comparative example 4 is that 520g of medical paraffin and 40g of medical vaseline are compounded without adding traditional Chinese medicine fine powder; comparative example 5 is a treatment in which 30g of medical vaseline, 520g of medical paraffin and 200g of fine powder of traditional Chinese medicine are mixed; 80g of medical vaseline used in comparative example 6, 450g of medical paraffin and 200g of traditional Chinese medicine fine powder are selected. Comparative examples 1 to 6 were prepared according to the preparation method given in example 1, and the melting point determination method was as described in example 1. The melting point measurements of comparative examples 1 to 6 and examples 1 to 6 are shown in Table 1.
Table 1 Material ratios and melting Point test data for each treatment group
From the test data shown in table 1, it can be seen that the phase change melting point of the phase change paste of the traditional Chinese medicine wax moxibustion can be well reduced after the medical vaseline is mixed with the medical paraffin according to a certain proportion, so that the phase change melting point meets the use requirement of < 45 ℃ and the occurrence of low-temperature scalds is avoided. Comparison of the test data of comparative example 1 and comparative example 3 shows that the melting point of the traditional Chinese medicine ointment is affected to a lesser extent by the traditional Chinese medicine fine powder. The weight ratio of the medical paraffin to the medical vaseline to the traditional Chinese medicine fine powder is 450-520:40-70: in the proportion of 200-300, the phase transition temperature of the phase transition paste of the Chinese medicinal wax moxibustion can be controlled within 40-45 ℃ excluding 45 ℃.
Greasy feel effect evaluation test
Based on the test protocol of example 3, the protocols of the fine powder of the traditional Chinese medicine containing 0 part of angelica dahurica (comparative example 7), 2 parts (comparative example 8), 5 parts (example 3) and 10 parts (example 3 a) are compared with a brand of wax moxibustion plaster A and wax moxibustion plaster B which are purchased from the market. In the experiment, 9 adult females (age in the range of 30-40 years) were randomly selected during the outpatient period, and were divided into A, B, C groups of three persons (respectively numbered A1, A2, A3; B1, B2, B3; C1, C2, C3), which were asked to experience the products of comparative example 7, comparative example 8, example 3 and example 3a, respectively, and were subjectively scored for the greasy feeling, the subjective feeling of the greasy feeling was divided into four levels of 0-3 (0 represents no greasy feeling, 1 represents weak greasy feeling, 2 represents greasy feeling, and 3 represents strong greasy feeling), and the subjective scores of the greasy feeling of the participants on the applicable wax moxibustion phase change cream were detailed, and the results are shown in Table 2.
TABLE 2 subjective feeling score for greasy feeling
As can be seen from the scoring results in Table 2, the addition of a proper amount of radix Angelicae Dahuricae powder (5-10 parts) to the wax moxibustion phase-change paste can significantly improve the greasy feeling of the skin caused by the use of the wax moxibustion paste and improve the comfort of patients. Compared with the existing wax moxibustion cream in the market, the invention has the advantages that the greasy feeling of human skin is obviously controlled after the formula is improved. Although the angelica dahurica can improve the greasiness of the wax moxibustion phase-change paste, the dosage cannot be excessive, otherwise the self-leveling performance of the wax moxibustion phase-change paste can be seriously affected, and the paste is easy to solidify too fast when the angelica dahurica is poured on a preservative film for flattening, thus causing trouble to flattening operation.
Repeated cycle use test
The phase change paste of wax moxibustion obtained in example 3 was compared with two commercially available traditional Chinese medicine wax moxibustion pastes of certain brands (A and B) by taking 750G, respectively heating example 3 and brands A and B in a microwave oven for 5 minutes after cooling and solidifying, heating in a microwave oven for 5 minutes again after cooling and solidifying, repeating circularly, recording the hardness performance of the paste after each standing and cooling and solidifying (measuring the penetration degree of the product, measuring the lower the penetration degree, indicating the higher the hardness, the worse the shaping property, the measuring method can refer to GB/T4985-1998 "petroleum wax penetration degree measuring method", the measuring method uses a domestic SYD-2801G penetration tester in the test, the instrument resolution is 0.01 mm), the drug taste performance (evaluated by using the smell of experimenters, the drug taste performance is divided into no, light, thick and 5 levels), the uniformity (using the naked eyes of experimenters, when the upper and lower obvious color difference appears after condensation, the uniformity of the paste and the base are not good, the layering test result and the difference of 3 obvious levels can be recorded after each layer of the condensation table shows that the performance is 3. And (3) injection: the measured penetration of the medical paraffin and the medical vaseline used in the test were 14.647mm and 201.548mm, respectively.
TABLE 3 penetration, taste and uniformity performance
As shown in Table 3, the penetration of the condensed phase change ointment of the traditional Chinese medicine wax moxibustion prepared by the invention is obviously increased due to the addition of medical vaseline, which is higher than that of the traditional Chinese medicine wax moxibustion ointment with single paraffin base on the market, and the shaping property of the phase change ointment is greatly improved compared with the existing product, and the phase change ointment has better fitting property with human body curve when in use. Although the medicine taste is obviously reduced after 15 times of recycling, the requirement of repeated use is basically met, the medicine taste release is not only related to the matrix, but also related to the formula of the traditional Chinese medicine fine powder, the dosage formulas of the brand A and the brand B are not clear, the difference exists for improving diseases, and the brand B medicine taste cannot be simply considered to have good overall effect after repeated recycling and larger medicine taste exists. In the aspect of uniformity of the wax moxibustion ointment, the wax block which is used for 10 times repeatedly has almost no layering phenomenon compared with the layering phenomenon of the brand A and the brand B, and the wax moxibustion ointment has obvious layering after 15 times of cyclic use and has better uniformity than the existing wax moxibustion ointment on the market.
The test results in table 3 show that the penetration of the single paraffin-based traditional Chinese medicine wax moxibustion paste is slightly reduced after a plurality of times of circulation, but after 15 times of circulation use, the penetration of the traditional Chinese medicine wax moxibustion phase change paste is still larger than that of the traditional Chinese medicine wax moxibustion paste, which shows that the hardness of the traditional Chinese medicine wax moxibustion phase change paste is smaller than that of the single paraffin-based wax moxibustion paste, but as the circulation heating times are increased, the low-melting point and volatile components in the phase change paste are more and more scattered along with heating, so that the enrichment of high-melting point wax and difficult volatile components is caused, and the penetration of the phase change paste is obviously reduced after a certain circulation times. In the clinical use, the invention can be recycled for 10 times to ensure the quality of the product and the curative effect on patients as waste judging standard. The waste-judged traditional Chinese medicine wax moxibustion phase change paste can be recovered to be used as a common wax therapy material or can play a role again after further supplementing traditional Chinese medicine fine powder.
It should be understood that while the present description has been described in terms of embodiments, such description is for clarity only, and that the description as a whole should be construed by those skilled in the art to form other embodiments that will be apparent to those skilled in the art, and should also fall within the scope of the invention.
Claims (2)
1. A traditional Chinese medicine wax moxibustion phase change paste is characterized in that: the phase-change ointment is prepared from 450-520 parts of medical paraffin, 40-70 parts of medical vaseline and 200-300 parts of traditional Chinese medicine fine powder, wherein each part of traditional Chinese medicine fine powder comprises 10-20 parts of radix angelicae pubescentis, 25-30 parts of mistletoe, 10-20 parts of eucommia ulmoides, 15-25 parts of medicinal cyathula root, 8-12 parts of frankincense, 8-14 parts of myrrh, 25-30 parts of rheum officinale, 3-8 parts of pericarpium zanthoxyli, 3-6 parts of borneol, 4-5 parts of fennel, 8-10 parts of green tangerine peel, 10-15 parts of rhizoma corydalis, 15-20 parts of ground beetle, 25-35 parts of lycopodium clavatum, 20-35 parts of suberect spatholobus stem and 5-10 parts of radix angelicae.
2. A method for preparing a phase change paste for wax moxibustion of traditional Chinese medicine according to claim 1, which is characterized by comprising the following steps:
(1) According to the weight portions of each traditional Chinese medicine fine powder, the traditional Chinese medicine fine powder consists of 10-20 portions of radix angelicae pubescentis, 25-30 portions of mistletoe, 10-20 portions of eucommia bark, 15-25 portions of medicinal cyathula root, 8-12 portions of frankincense, 8-14 portions of myrrh, 25-30 portions of rheum officinale, 3-8 portions of pericarpium zanthoxyli, 3-6 portions of borneol, 4-5 portions of fennel, 8-10 portions of green tangerine peel, 10-15 portions of rhizoma corydalis, 15-20 portions of ground beetle, 25-35 portions of lycopodium clavatum, 20-35 portions of suberect spatholobus stem and 5-10 portions of angelica dahurica, after weighing, crushing the traditional Chinese medicine fine powder into 200-mesh fine powder, and uniformly mixing the fine powder for standby;
(2) And (2) adding 450-520 parts of medical paraffin, 40-70 parts of medical vaseline and 200-300 parts of traditional Chinese medicine fine powder according to the weight ratio, heating and melting the medical paraffin to be liquid, adding the medical vaseline, continuously stirring until the medical paraffin is completely melted and uniformly mixed, adding the traditional Chinese medicine fine powder prepared in advance in the step (1), uniformly stirring, continuously heating until the traditional Chinese medicine fine powder is completely melted to be thin paste, pouring the thin paste into a clean container with a cover, and sealing and storing at normal temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210685010.8A CN114869946B (en) | 2022-06-15 | 2022-06-15 | Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210685010.8A CN114869946B (en) | 2022-06-15 | 2022-06-15 | Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114869946A CN114869946A (en) | 2022-08-09 |
| CN114869946B true CN114869946B (en) | 2023-06-20 |
Family
ID=82681233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210685010.8A Active CN114869946B (en) | 2022-06-15 | 2022-06-15 | Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114869946B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115381921B (en) * | 2022-08-26 | 2023-10-27 | 吉林省中医药科学院（吉林省中医药科学院第一临床医院） | Traditional Chinese medicine composition and medicinal wax for treating knee osteoarthritis and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102920987B (en) * | 2012-11-03 | 2014-07-23 | 乔守军 | Acupuncture point soft body wax moxibustion medicine for external application and manufacture and external application methods thereof |
| CN109589396A (en) * | 2018-12-17 | 2019-04-09 | 郭宇欣 | A kind of Moxa conditioning essential oil and preparation method thereof |
-
2022
- 2022-06-15 CN CN202210685010.8A patent/CN114869946B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN114869946A (en) | 2022-08-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101317996B (en) | Traditional Chinese medicine emplastrum for rheumatism of muscles and bones | |
| CN104857157A (en) | Decoction medicine for treating endometrial hyperplasia and preparation method thereof | |
| CN114869946B (en) | Traditional Chinese medicine wax moxibustion phase change paste and preparation method thereof | |
| CN104173264B (en) | Rose essence oil hydrogel patch and preparation method thereof | |
| CN102755436A (en) | External use drug for treating rheumatoid arthritis and preparation method thereof | |
| CN102302605A (en) | Angelica dahurica, goldthread and Chinese angelica powder for cracked nipple | |
| CN101507776A (en) | Traditional Chinese medicine preparation for treating kidney deficiency, waist and knees soreness and preparation method thereof | |
| CN102205064B (en) | Traditional Chinese medicine (TCM) for treating threatened abortion | |
| CN103203006A (en) | Traditional Chinese medicine decoction for treating uterus coldness | |
| CN102274417A (en) | Chinese patent medicament for treating aplastic anemia | |
| CN102846872B (en) | Traditional Chinese medicine for treating facial paralysis and preparation method thereof | |
| CN103977367A (en) | Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof | |
| CN1546088A (en) | Dysmenorrhea treating Chinese traditional medicine preparation | |
| CN104740481A (en) | Traditional Chinese medicine for treating functional uterine bleeding | |
| CN104958723A (en) | Wine with gentiana macrophylla, cinnamon, poria cocos and astragalus | |
| CN104042930A (en) | Traditional Chinese medicine composition for nourishing blood and tonifying kidney | |
| CN103989968A (en) | Oral traditional Chinese medicinal composition for treating cervical spinal stenosis | |
| CN104189402A (en) | Traditional Chinese medicine preparation for treating uterine bleeding | |
| CN103751301A (en) | Product for patients with aseptic necrosis of femoral head | |
| CN103536839A (en) | Medicament for treating cystitis and preparation method thereof | |
| CN105920255A (en) | Ointment for orthopedics department and production method thereof | |
| CN101274061A (en) | Compound formulation of capsules for nourishing yin and preparing process | |
| CN104689156A (en) | Medicinal preparation for treatment of chloasma spleen deficiency syndrome of accumulated dampness-toxicity and preparation method thereof | |
| CN106038802A (en) | Preparation method of traditional Chinese medicinal composition for treating premature ovarian failure of women and traditional Chinese medicinal composition | |
| CN104800824A (en) | Soft capsule for treating postpartum lochiorrhea and preparation method of soft capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |