CN114752497A - Sterile culture device for preparing influenza vaccine - Google Patents

Sterile culture device for preparing influenza vaccine Download PDF

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Publication number
CN114752497A
CN114752497A CN202210676786.3A CN202210676786A CN114752497A CN 114752497 A CN114752497 A CN 114752497A CN 202210676786 A CN202210676786 A CN 202210676786A CN 114752497 A CN114752497 A CN 114752497A
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plate
shaped
column
air
gas
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陈则
王帅
张玉辉
贾春玉
王凯
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Jiangsu Zhonghui Yuantong Biotechnology Co ltd
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Jiangsu Zhonghui Yuantong Biotechnology Co ltd
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Priority to CN202210676786.3A priority Critical patent/CN114752497A/en
Publication of CN114752497A publication Critical patent/CN114752497A/en
Priority to CN202211338331.7A priority patent/CN115537337A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/10Bioreactors or fermenters specially adapted for specific uses adapted for the cultivation of avian eggs or in avian eggs, e.g. for vaccine production
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/20Heat exchange systems, e.g. heat jackets or outer envelopes the heat transfer medium being a gas
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
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Abstract

The invention relates to the technical field of vaccine culture, in particular to an aseptic culture device for preparing influenza vaccine, which comprises a shelter shell, wherein a plurality of uniformly distributed main control frames are arranged in the shelter shell, each main control frame comprises a conveying belt, a gas control assembly, a power assembly, a sliding rail member and a door assembly, a plurality of uniformly distributed gas control assemblies are arranged above the conveying belt, the structural design of the invention realizes the process of conveying a vessel bottle to the outside of a shelter, only an electronic gas valve above the conveying belt needs to be controlled to be opened, and meanwhile, a collecting and distributing pipe is supplied with temperature gas flow, the transmission control of the gas control assembly and the power assembly can be triggered, the gas control assembly and the power assembly are matched to realize the effect of highly automatic control, and then appointed household utensils bottle is outside by accurate transport shelter casing, and the inside temperature of in-process shelter casing is lived by effective management and control, and the inside constant temperature culture environment of guarantee shelter casing is stable.

Description

Sterile culture device for preparing influenza vaccine
Technical Field
The invention relates to the technical field of vaccine culture, in particular to an aseptic culture device for preparing an influenza vaccine.
Background
In the sterile culture process for preparing influenza vaccine in the prior art, a plurality of culture temperature control square cabins are placed in a sterile room and used for storing a plurality of culture dishes or culture eggs, the vaccine is injected into the culture dishes or culture eggs and used for culturing the vaccine, the temperature in the square cabin needs to be controlled to ensure the safe growth of bacteria, workers need to take out the culture dishes or the eggs regularly and observe and treat the culture dishes or the eggs, so that the constant temperature environment in the square cabin is influenced, a constant temperature compensation mechanism of the sterile culture system is provided for the people, after a square cabin door is opened, the heat in the square cabin overflows, the constant temperature compensation mechanism continuously injects air flow with temperature into the square cabin in the opening stage of the square cabin door to ensure the internal temperature of the square cabin without influencing other bacteria cultured in the square cabin, and the temperature compensation mechanism in the square cabin is matched and connected with a culture dish accurate conveying mechanism, only need to the air feed of temperature compensation mechanism, open through the electronic pneumatic valve of system master control terminal management and control assigned position simultaneously, trigger a series of automated work in the shelter promptly, promote the intelligent automated control effect of whole cultivation shelter.
Disclosure of Invention
The invention aims to provide an influenza vaccine preparation sterile culture device to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: an aseptic culture device for preparing influenza vaccines comprises a shelter shell, wherein a plurality of uniformly distributed main control frames are arranged in the shelter shell, each main control frame comprises a conveying belt, an air control assembly, a power assembly, a sliding rail piece and a door assembly, the plurality of uniformly distributed air control assemblies are arranged above the conveying belt, one end of each air control assembly is provided with the power assembly, the sliding rail pieces are distributed on one side of the conveying belt in parallel and are in transmission connection with the air control assemblies, parts of the conveying belt and the sliding rail pieces extend out of the shelter shell, a plurality of uniformly distributed square holes are formed in the shell on one side of the shelter shell, the door assemblies are blocked at the square holes of the shelter shell, each sliding rail piece comprises a blocking plate, an L-shaped short plate, a tension spring, a braking plate, a direction control rail column and a braking long plate, a T-shaped columnar direction control rail column is distributed on one side of the braking long plate in parallel, the direction control rail column is arranged in a T-shaped sliding groove formed in the long braking plate.
Preferably, the one end of accuse rail post extends to the braking long slab outside, and just accuse rail post tip fixedly connected with interception board, is fixed with the short board of L type on the braking long slab of interception board one side, and one side fixedly connected with extension spring of interception board, the one end fixedly connected with braking plate of extension spring, the braking plate is fixed on the braking long slab, is provided with a plurality of evenly distributed's protruding tooth on the lateral wall of braking long slab.
Preferably, the door subassembly includes switch door, keeper pole, pressure plate and concave grillage, the square hole department of switch door shutoff on the shelter casing, the one end fixed connection pressure plate of switch door, the one end top of keeper pole is on the pressure plate, the other end contact L type short slab of keeper pole, fixed concave grillage on the shells inner wall of shelter casing, the keeper pole runs through the inner chamber of concave grillage, keeper pole part activity cup joints in the through-hole of seting up on shelter casing.
Preferably, accuse gas subassembly includes riser, gas column, cuts off piece, sleeve, L type accuse to board, first spring, household utensils bottle, lifting plate frame, loading board and L type trachea, the upper end of riser extends to the shelter casing outside, and the inside activity of lower extreme of riser has cup jointed the gas column, and one side intercommunication of riser has L type trachea, and the tracheal one end of L type extends to power component in, the cover has sleeve and first spring on the gas column, and the sleeve fixed cover is on the gas column, and the upper end contact sleeve of first spring, the lower extreme contact L type of first spring accuse to the board, and one side fixed connection of gas column cuts off the piece, cuts off the piece setting in the trompil hole that the board was seted up to L type accuse, and the gas column runs through the plate body of L type accuse to the board.
Preferably, the bottom fixedly connected with of gas column lifts the grillage, lift the grillage shape and be the integrative riser of connecting between the L template of two parallel distributions, lifts on the lifting grillage and has loaded the board, loads the board and be T type platelike, and loads and offer the disc groove on the board body, places the household utensils bottle in the disc groove of loading the board.
Preferably, power component includes a pressure boost section of thick bamboo, L type vaulting pole, fan, external frame, a section of thick bamboo gear, elevator, cross axle, second spring, L type interception board, fishplate bar, internal control post, air duct and gas box, L type interception board one side sliding contact has the elevator, and it has the cross axle to run through on the elevator, and the fixed cover of one end of cross axle has a section of thick bamboo gear, and the fixed cover of the other end of cross axle has the fan, and the fan shape is the square slab that a plurality of evenly distributed are established to the ring on the drum lateral wall, and the braking long slab is connected in the transmission of section of thick bamboo gear below, and the braking long slab is located under the section of thick bamboo gear, and section of thick bamboo gear whereabouts is connected with the meshing of braking long slab.
Preferably, a trapezoidal cylindrical pressurizing cylinder is arranged above the fan, an air box is arranged below the fan, the pressurizing cylinder is in a funnel shell shape, an L-shaped air pipe is arranged above the pressurizing cylinder, the bottom end of the L-shaped air pipe extends into the pressurizing cylinder, and an L-shaped support rod is fixedly connected between the pressurizing cylinder and the lifting block.
Preferably, an inner control column is fixedly connected to the lower portion of the lifting block, a second spring is sleeved on the inner control column, the second spring is cushioned between the lifting block and the L-shaped interception plate, the inner control column is movably sleeved in a through hole formed in a bottom plate of the L-shaped interception plate, one side of the bottom of a vertical plate of the L-shaped interception plate is fixedly connected with a U-shaped plate-shaped inner connection plate, one end of the inner connection plate is fixed on the L-shaped interception plate, the other end of the inner connection plate is fixed on a gas box, the gas box is in a square box shell shape with an opening at the top, one side of the top of the vertical plate of the L-shaped interception plate is fixedly connected with an external frame, one end of the external frame is fixedly connected with the direction control rail column, the direction control rail column portion protrudes to the outside of the braking long plate, and the external frame is fixed on the protruding portion of the direction control rail column.
Preferably, the gas box is a box shell body with an open top, one side of the gas box is communicated with a gas guide tube, a part of the gas guide tube body is distributed above the conveying belt in parallel, and a plurality of uniformly distributed through holes are formed in the part of the gas guide tube body.
Compared with the prior art, the invention has the beneficial effects that:
1. the structural design of the invention realizes the process of sending the vessel bottle to the outside of the shelter, the transmission control of the gas control assembly and the power assembly can be triggered only by controlling the opening of the electronic gas valve above the vessel bottle and supplying temperature air flow to the collecting and distributing pipe, the gas control assembly and the power assembly are matched to realize the effect of highly automatic control, and further the specified vessel bottle is accurately sent to the outside of the shelter shell, and the temperature in the shelter shell is effectively controlled in the process, so that the stability of the constant temperature culture environment in the shelter shell is ensured;
2. according to the invention, a series of exquisite transmission parts are arranged in the gas control assembly and the power assembly, so that the kinetic energy of the airflow is effectively controlled and guided, and further, the automatic control effect is realized.
Drawings
FIG. 1 is a schematic view of the structure of the present invention.
Fig. 2 is a schematic structural diagram of a main control rack.
Fig. 3 is a schematic structural view of the slide rail member.
Fig. 4 is a schematic view of the structure of the conveyor belt.
FIG. 5 is a schematic view of a door assembly configuration.
FIG. 6 is a schematic view of a gas control assembly.
Fig. 7 is a schematic structural view of the power assembly.
FIG. 8 is a schematic view of the airway tube configuration.
Fig. 9 is a schematic view of the gas box structure.
Fig. 10 is a schematic view of a brake long plate structure.
Fig. 11 is an L-shaped trachea position distribution diagram.
Fig. 12 is a schematic view of the structure at a in fig. 11.
In the figure: the device comprises a shelter shell 1, a main control frame 2, a conveying belt 3, an air control assembly 4, a power assembly 5, a slide rail member 6, a door assembly 7, an electronic air valve 8, a collecting and distributing pipe 9, a blocking plate 10, an L-shaped short plate 11, a tension spring 12, a braking plate 13, a control rail column 14, a braking long plate 15, a switch door 16, a door bolt rod 17, a pressure plate 18, a concave plate frame 19, a vertical pipe 20, an air column 22, a blocking block 23, a sleeve 24, an L-shaped control plate 25, a first spring 26, a vessel bottle 27, a lifting plate frame 28, a loading plate 29, an L-shaped air pipe 30, a pressurizing cylinder 31, an L-shaped supporting rod 32, a fan 33, an external connecting frame 34, a cylinder gear 35, a lifting block 36, a transverse shaft 37, a second spring 38, an L-shaped blocking plate 39, an internal connecting plate 40, an internal control column 41, an air guide pipe 42 and an air box 43.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. Based on the technical solutions in the present invention, all other embodiments obtained by a person of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.
Referring to fig. 1 to 12, the present invention provides a technical solution: an aseptic culture device for preparing influenza vaccine comprises a shelter shell 1, wherein a plurality of uniformly distributed main control frames 2 are arranged in the shelter shell 1, each main control frame 2 comprises a conveying belt 3, a gas control assembly 4, a power assembly 5, a sliding rail piece 6 and a door assembly 7, a plurality of uniformly distributed gas control assemblies 4 are arranged above the conveying belts 3, one end of each gas control assembly 4 is provided with the power assembly 5, one side of each conveying belt 3 is provided with a sliding rail piece 6 in parallel, the sliding rail pieces 6 are in transmission connection with the gas control assemblies 4, parts of the conveying belts 3 and the sliding rail pieces 6 extend out of the shelter shell 1, a plurality of uniformly distributed square holes are formed in the shell on one side of the shelter shell 1, the door assemblies 7 are blocked at the square holes of the shelter shell 1, each sliding rail piece 6 comprises a blocking plate 10, an L-shaped short plate 11, a tension spring 12, a brake plate 13, a direction control rail column 14 and a brake long plate 15, one side of the long brake plate 15 is provided with a T-shaped columnar direction control rail column 14 in parallel, the direction control rail column 14 is arranged in a T-shaped sliding groove formed in the long braking plate 15.
One end of a direction control rail column 14 extends to the outside of a long braking plate 15, the end of the direction control rail column 14 is fixedly connected with an interception plate 10, an L-shaped short plate 11 is fixed on the long braking plate 15 on one side of the interception plate 10, a tension spring 12 is fixedly connected on one side of the interception plate 10, one end of the tension spring 12 is fixedly connected with a braking plate 13, the braking plate 13 is fixed on the long braking plate 15, a plurality of protruding teeth which are uniformly distributed are arranged on one side wall of the long braking plate 15, as can be understood by referring to fig. 4, the conveying belt 3 is a conveying belt mechanism in the prior art, a gear structure is arranged on a driving shaft at one end of the conveying belt, the gear structure is in meshing transmission connection with the long braking plate 15, and the conveying belt is driven by movement of the long braking plate 15.
The door component 7 comprises a switch door 16, a door bolt rod 17, a pressure plate 18 and a concave plate frame 19, the switch door 16 is plugged at a square hole on the shelter shell 1, one end of the switch door 16 is fixedly connected with the pressure plate 18, one end of the door bolt rod 17 is propped against the pressure plate 18, the other end of the door bolt rod 17 is contacted with the L-shaped short plate 11, the concave plate frame 19 is fixed on the inner wall of the shell of the shelter shell 1, the door bolt rod 17 penetrates through the inner cavity of the concave plate frame 19, part of rod bodies of the door bolt rod 17 are movably sleeved in through holes formed in the shell of the shelter shell 1, as understood by referring to figure 12, the switch door 16 is an upper and lower flip-top rotating door controlled by a torsion spring in the prior art, the rotating shaft of the door is sleeved with the torsion spring, one end of the torsion spring is fixed on the shell of the shelter shell 1, the torsion spring applies continuous elasticity to the door, the pressure plate 18 fixedly connected with one end of the door shaft is propped by the door bolt rod 17, if the door bolt rod 17 is retracted into the shelter shell 1, at this time, the door shaft only stressed by the torsion spring rotates, the door plate turns upwards to expose the square discharge hole on the shelter shell 1, and the door bolt rod 17 retracts into the shelter shell 1 because the L-shaped short plate 11 moves and does not support the bottom end of the door bolt rod 17 any more.
The gas control assembly 4 comprises a vertical pipe 20, a gas column 22, a stop block 23, a sleeve 24, an L-shaped direction control plate 25, a first spring 26, a vessel bottle 27, a lifting plate frame 28, a loading plate 29 and an L-shaped gas pipe 30, wherein the upper end of the vertical pipe 20 extends to the outside of the shelter shell 1, the gas column 22 is movably sleeved inside the lower end of the vertical pipe 20, one side of the vertical pipe 20 is communicated with the L-shaped gas pipe 30, one end of the L-shaped gas pipe 30 extends into the power assembly 5, the sleeve 24 and the first spring 26 are sleeved on the gas column 22, the sleeve 24 is fixedly sleeved on the gas column 22, the upper end of the first spring 26 is contacted with the sleeve 24, the lower end of the first spring 26 is contacted with the L-shaped direction control plate 25, one side of the gas column 22 is fixedly connected with the stop block 23, the stop block 23 is arranged in a long hole formed in the L-shaped direction control plate 25, the gas column 22 penetrates through a plate body of the L-shaped direction control plate 25, as can be understood by referring to fig. 2 and fig. 6, the top end of the vertical pipe 20 is connected with the electronic gas valve 8 in the prior art, the collecting and distributing pipe 9 is connected with a plurality of electronic air valves 8, one end of the collecting and distributing pipe 9 is connected with a hot air supply mechanism in the prior art, the air supply process is carried out in the shelter shell 1, the regulation and control terminal of the culture system is controlled, the appointed electronic air valves 8 are controlled to work, the top ends of the corresponding vertical pipes 20 are in a smooth state, the hot air injected into the collecting and distributing pipe 9 is then injected into the vertical pipes 20, and the control on the air control assembly 4 and the power assembly 5 is further triggered.
The bottom end of the gas column 22 is fixedly connected with a lifting plate frame 28, the lifting plate frame 28 is in the shape of an integrally connected vertical plate between two L-shaped plates which are distributed in parallel, a loading plate 29 is lifted on the lifting plate frame 28, the loading plate 29 is in a T-shaped plate shape, a circular plate groove is formed in the plate body of the loading plate 29, and a vessel bottle 27 is placed in the circular plate groove of the loading plate 29.
The power assembly 5 comprises a pressurizing cylinder 31, an L-shaped support rod 32, a fan 33, an external connection frame 34, a cylinder gear 35, a lifting block 36, a transverse shaft 37, a second spring 38, an L-shaped interception plate 39, an internal connection plate 40, an internal control column 41, an air guide pipe 42 and an air box 43, wherein the lifting block 36 is in sliding contact with one side of the L-shaped interception plate 39, the transverse shaft 37 penetrates through the lifting block 36, the cylinder gear 35 is fixedly sleeved at one end of the transverse shaft 37, the fan 33 is fixedly sleeved at the other end of the transverse shaft 37, the fan 33 is in a shape that a plurality of square plates which are uniformly distributed are annularly arranged on the outer side wall of a cylinder, the lower part of the cylinder gear 35 is in transmission connection with a braking long plate 15, the braking long plate 15 is positioned under the cylinder gear 35, and the cylinder gear 35 falls down and is in meshing connection with the braking long plate 15.
A ladder-shaped cylindrical pressurizing cylinder 31 is arranged above the fan 33, an air box 43 is arranged below the fan 33, the pressurizing cylinder 31 is in a funnel shell shape, an L-shaped air pipe 30 is arranged above the pressurizing cylinder 31, the bottom end of the L-shaped air pipe 30 extends into the pressurizing cylinder 31, an L-shaped support rod 32 is fixedly connected between the pressurizing cylinder 31 and the lifting block 36, and as understood by referring to fig. 11, the closing-up inner diameter of the pressurizing cylinder 31 is smaller than the air outlet of the L-shaped air pipe 30, so that the air flow sprayed out of the L-shaped air pipe 30 impacts on the pressurizing cylinder 31 to force the pressurizing cylinder 31 to fall.
An inner control column 41 is fixedly connected below the lifting block 36, a second spring 38 is sleeved on the inner control column 41, the second spring 38 is cushioned between the lifting block 36 and the L-shaped interception plate 39, the inner control column 41 is movably sleeved in a through hole formed in a bottom plate of the L-shaped interception plate 39, one side of the bottom of a vertical plate of the L-shaped interception plate 39 is fixedly connected with a U-shaped plate-shaped inner connecting plate 40, one end of the inner connecting plate 40 is fixed on the L-shaped interception plate 39, the other end of the inner connecting plate 40 is fixed on a gas box 43, the gas box 43 is in a shape of a square box shell with an opening at the top, one side of the top of the vertical plate of the L-shaped interception plate 39 is fixedly connected with an external frame 34, one end of the external frame 34 is fixedly connected with the direction control rail column 14, the direction control rail column 14 partially protrudes out of the braking long plate 15, and the external frame 34 is fixed on a protruding part of the direction control rail column 14.
The gas box 43 is in a box shell shape with an open top, one side of the gas box 43 is communicated with the gas guide tubes 42, part of the gas guide tubes 42 are distributed above the conveying belt 3 in parallel, a plurality of through holes are uniformly distributed in the part of the gas guide tubes, the position distribution of the gas guide tubes 42 is understood by referring to fig. 8, and thus hot gas exhausted from the gas guide tubes 42 can be rapidly diffused in the shelter shell 1.
When the vessel bottle 27 at the designated position needs to be inspected or injected with nutrition, the electronic air valve 8 above the vessel bottle is controlled to be opened, hot air is supplied into the collecting and distributing pipe 9, then the hot air is injected into the designated vertical pipe 20, the air pressure in the vertical pipe 20 rises, and the air column 22 is ejected downwards, the air column 22 overcomes the elastic pushing influence of the first spring 26 in the downward extending process, the air column 22 drives the lifting plate frame 28, the lifting plate frame 28 controls the loading plate 29 to fall, when the loading plate 29 falls onto the conveying belt 3, the lifting plate frame 28 continues to fall behind, the loading plate 29 and the lifting plate frame 28 are separated, at the moment, the loading plate 29 lifts the lifting plate frame 28 to fall on the conveying belt 3 completely, at the moment, the air column 22 extends downwards to the maximum distance, the top end of the air column 22 falls below the L-shaped air pipe 30, so that the hot air injected into the vertical pipe 20 is injected into the L-shaped air pipe 30 subsequently, referring to the attached figure 6 of the specification, the loading plate 29 is specifically shaped as a square plate with a convex plate integrally connected at the bottom, and a circular plate groove for placing the vessel bottle 27 is formed in the square plate, so that after the lifting plate frame 28 falls down, the convex plate part of the loading plate 29 is firstly contacted with the conveying belt, and the lifting plate frame 28 continuously falls down, so that the separation between the lifting plate frame 28 and the loading plate 29 can be realized; when the air in the vertical pipe 20 is injected into the L-shaped air pipe 30, one end of the L-shaped air pipe 30 is communicated with the vertical pipe 20, the top of the air column 22 extends into the vertical pipe 20 and blocks the top opening of the L-shaped air pipe 30, after the air is introduced into the vertical pipe 20, the air pressure in the vertical pipe 20 lowers the air column 22 and then exposes the top opening of the L-shaped air pipe 30, so that the air in the vertical pipe 20 is injected into the L-shaped air pipe 30, the hot air flow is ejected from the L-shaped air pipe 30 and impacts the pressurizing cylinder 31, the pressurizing cylinder 31 falls down and drives the L-shaped support rod 32, the lifting block 36 falls down, the lifting block 36 drives the transverse shaft 37, the cylinder gear 35 is controlled, the cylinder gear 35 falls down for a short distance and is meshed with the braking long plate 15, in addition, the fan 33 falls along with the short distance, the lifting space of the fan 33 is provided between the pressurizing cylinder 31 and the air box 43, and the hot air flow ejected from the pressurizing cylinder 31 impacts the fan 33, the fan 33 is controlled to rotate, then hot air flow impacts the air box 43 and is diffused above the conveying belt 3 after being guided by the air guide pipe 42 to assist in heating the inner space of the shelter shell 1, the fan 33 rotates to drive the transverse shaft 37, further the barrel gear 35 is controlled to rotate, the barrel gear 35 drives the long braking plate 15, the long braking plate 15 slides under the directional guide of the control rail column 14, the long braking plate 15 moves away from the interception plate 10, the tension spring 12 elastically pulls the long braking plate 15 to realize the later reset of the long braking plate 15, the long braking plate 15 moves to drive the L-shaped short braking plate 11, the L-shaped short plate 11 moves along with the initial movement, the L-shaped short plate 11 does not support the door bolt rod 17 any more, the door opening and turning operation of the switch door 16 is directly triggered, the top end of the L-shaped short plate 11 is finally intercepted by the transverse shaft 37 falling down in the short-distance movement process of the long braking plate 15, and the L-shaped short plate 11 reversely controls the long braking plate 15, therefore, the drum gear 35 continuously rotates and cannot drive the long braking plate 15, the drum gear 35 is jacked up for a certain distance, the meshing state between the drum gear 35 and the long braking plate 15 is broken, even if the fan 33 continuously rotates, the clamping state between the L-shaped short plate 11 and the transverse shaft 37 exists, the long braking plate 15 is still all the time, the long braking plate 15 drives the driving shaft on the conveying belt 3, the conveying belt 3 works and conveys the loading plate 29 falling onto the conveying belt 3, the conveying belt 3 is static after conveying for a specified distance, at the moment, the loading plate 29 drives the vessel bottle 27 to move to the end position of the conveying belt 3 outside the shelter shell 1, and therefore a worker can process culture solution in the vessel bottle 27.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (7)

1. An influenza vaccine preparation is with aseptic culture apparatus, includes shelter casing (1), its characterized in that: the square cabin comprises a square cabin shell (1), wherein a plurality of uniformly distributed main control frames (2) are arranged in the square cabin shell (1), each main control frame (2) comprises a conveying belt (3), an air control assembly (4), a power assembly (5), a sliding rail piece (6) and a door assembly (7), the plurality of uniformly distributed air control assemblies (4) are arranged above the conveying belt (3), the power assembly (5) is arranged at one end of each air control assembly (4), the sliding rail pieces (6) are distributed on one side of the conveying belt (3) in parallel, the sliding rail pieces (6) are in transmission connection with the air control assemblies (4), a plurality of holes for the conveying belts (3) and the sliding rail pieces (6) to penetrate through are formed in the square cabin shell (1), parts of the conveying belt (3) and the sliding rail pieces (6) extend to the outside of the square cabin shell (1), a plurality of uniformly distributed square holes are formed in one side of the square cabin shell (1), and the door assemblies (7) are blocked at the square holes of the square cabin shell (1), the slide rail part (6) comprises a blocking plate (10), an L-shaped short plate (11), a tension spring (12), a brake plate (13), a direction control rail column (14) and a long brake plate (15), wherein the T-shaped columnar direction control rail column (14) is distributed on one side of the long brake plate (15) in parallel, the direction control rail column (14) is arranged in a T-shaped slide groove formed in the long brake plate (15), the gas control assembly (4) comprises a vertical pipe (20), a gas column (22), a stop block (23), a sleeve (24), an L-shaped direction control plate (25), a first spring (26), a vessel bottle (27), a lifting plate frame (28), a loading plate (29) and an L-shaped gas pipe (30), the upper end of the vertical pipe (20) extends to the outside of the shelter shell (1), the gas column (22) is movably sleeved in the lower end of the vertical pipe (20), and the L-shaped gas pipe (30) is communicated with one side of the vertical pipe (20), one end of an L-shaped air pipe (30) extends into the power assembly (5), a sleeve (24) and a first spring (26) are sleeved on the air column (22), the sleeve (24) is fixedly sleeved on the air column (22), the upper end of the first spring (26) is in contact with the sleeve (24), the lower end of the first spring (26) is in contact with an L-shaped direction control plate (25), one side of the air column (22) is fixedly connected with a stop block (23), the stop block (23) is arranged in a long plate hole formed in the L-shaped direction control plate (25), the air column (22) penetrates through a plate body of the L-shaped direction control plate (25), the bottom end of the air column (22) is fixedly connected with a lifting plate frame (28), the lifting plate frame (28) is in a shape that a vertical plate is integrally connected between two L-shaped plates which are distributed in parallel, a loading plate (29) is lifted on the lifting plate frame (28), the loading plate (29) is in a T-shaped plate shape, and a round plate groove is formed in the loading plate body of the loading plate (29), the vessel bottle (27) is placed in the circular plate groove of the loading plate (29).
2. The sterile culture apparatus for preparing an influenza vaccine according to claim 1, wherein: the one end of accuse to rail post (14) extends to braking long slab (15) outside, and accuse to rail post (14) tip fixedly connected with interception board (10), be fixed with L type short slab (11) on the braking long slab (15) of interception board (10) one side, one side fixedly connected with extension spring (12) of interception board (10), the one end fixedly connected with braking plate (13) of extension spring (12), braking plate (13) are fixed on braking long slab (15), be provided with a plurality of evenly distributed's protruding tooth on the lateral wall of braking long slab (15).
3. The sterile culture apparatus for preparing an influenza vaccine according to claim 1, wherein: door subassembly (7) are including switch door (16), keeper pole (17), pressure plate (18) and concave grillage (19), square hole department of switch door (16) shutoff on shelter casing (1), one end fixed connection pressure plate (18) of switch door (16), the one end top of keeper pole (17) is on pressure plate (18), the other end contact L type short slab (11) of keeper pole (17), fixed concave grillage (19) on the shells inner wall of shelter casing (1), the inner chamber of concave grillage (19) is run through in keeper pole (17), keeper pole (17) part body of rod activity cup joints in the through-hole of seting up on shelter casing (1).
4. The sterile culture apparatus for preparing an influenza vaccine according to claim 1, wherein: the power component (5) comprises a pressurizing cylinder (31), an L-shaped stay bar (32), a fan (33), an external connecting frame (34), a cylinder gear (35), a lifting block (36), a transverse shaft (37), a second spring (38), an L-shaped interception plate (39), an internal connecting plate (40), an internal control column (41), an air duct (42) and an air box (43), l type blocks board (39) one side sliding contact and has elevator (36), it has cross axle (37) to run through on elevator (36), the fixed cover of one end of cross axle (37) has section of thick bamboo gear (35), the fixed cover of the other end of cross axle (37) has fan (33), fan (33) shape is the square plate that a plurality of evenly distributed's were established to the ring on the drum lateral wall, braking long slab (15) are connected in section of thick bamboo gear (35) below transmission, braking long slab (15) are located section of thick bamboo gear (35) under, section of thick bamboo gear (35) whereabouts are connected with braking long slab (15) meshing.
5. The sterile culture apparatus for preparing an influenza vaccine according to claim 4, wherein: a trapezoidal cylindrical pressurizing cylinder (31) is arranged above the fan (33), an air box (43) is arranged below the fan (33), the pressurizing cylinder (31) is in a funnel shell shape, an L-shaped air pipe (30) is arranged above the pressurizing cylinder (31), the bottom end of the L-shaped air pipe (30) extends into the pressurizing cylinder (31), and an L-shaped support rod (32) is fixedly connected between the pressurizing cylinder (31) and the lifting block (36).
6. The sterile culture apparatus for preparing an influenza vaccine according to claim 4, wherein: an inner control column (41) is fixedly connected below the lifting block (36), a second spring (38) is sleeved on the inner control column (41), the second spring (38) is cushioned between the lifting block (36) and the L-shaped interception plate (39), the inner control column (41) is movably sleeved in a through hole formed in the bottom plate of the L-shaped interception plate (39), one side of the bottom of a vertical plate of the L-shaped interception plate (39) is fixedly connected with a U-shaped plate-shaped inner connecting plate (40), one end of the inner connecting plate (40) is fixed on the L-shaped interception plate (39), the other end of the inner connecting plate (40) is fixed on a gas box (43), the gas box (43) is in a square box shell shape with an opening at the top, one side of the top of the vertical plate of the L-shaped interception plate (39) is fixedly connected with an external frame (34), one end of the external frame (34) is fixedly connected with a direction control rail column (14), part of the direction control rail column (14) protrudes to the outside of the long braking plate (15), and the external frame (34) is fixed on the protruding part of the direction control rail column (14).
7. The sterile culture apparatus for preparing an influenza vaccine according to claim 4, wherein: the gas box (43) is in a box shell body shape with an opening at the top, one side of the gas box (43) is communicated with a gas guide pipe (42), part of the pipe body of the gas guide pipe (42) is distributed above the conveying belt (3) in parallel, and a plurality of uniformly distributed through holes are formed in the part of the pipe body.
CN202210676786.3A 2022-06-16 2022-06-16 Sterile culture device for preparing influenza vaccine Pending CN114752497A (en)

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CN202210676786.3A CN114752497A (en) 2022-06-16 2022-06-16 Sterile culture device for preparing influenza vaccine
CN202211338331.7A CN115537337A (en) 2022-06-16 2022-10-28 Sterile culture device for preparing influenza vaccine

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CN202210676786.3A CN114752497A (en) 2022-06-16 2022-06-16 Sterile culture device for preparing influenza vaccine

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CN202211338331.7A Pending CN115537337A (en) 2022-06-16 2022-10-28 Sterile culture device for preparing influenza vaccine

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105238692A (en) * 2015-09-18 2016-01-13 天津开发区合普工贸有限公司 Multifunctional experiment chicken embryo culture and detection device
CN107205365A (en) * 2015-01-26 2017-09-26 硕腾服务有限责任公司 Equipment and associated method for harvesting eggs fluid
CN108471727A (en) * 2015-08-18 2018-08-31 赛瓦动物医疗有限公司 Selectively apply the improvement of the function module of substance in fertile egg
CN111575188A (en) * 2020-06-22 2020-08-25 张雅琴 Epithelial cell culture device capable of automatically conveying detection sample
CN113444643A (en) * 2021-05-24 2021-09-28 邵小文 Clinical laboratory is with bacterin research and development virus culture apparatus
CN113637587A (en) * 2021-09-02 2021-11-12 大连雅立峰生物制药有限公司 Full-automatic high-speed chick embryo dish changing and disinfecting linkage device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107205365A (en) * 2015-01-26 2017-09-26 硕腾服务有限责任公司 Equipment and associated method for harvesting eggs fluid
CN108471727A (en) * 2015-08-18 2018-08-31 赛瓦动物医疗有限公司 Selectively apply the improvement of the function module of substance in fertile egg
CN105238692A (en) * 2015-09-18 2016-01-13 天津开发区合普工贸有限公司 Multifunctional experiment chicken embryo culture and detection device
CN111575188A (en) * 2020-06-22 2020-08-25 张雅琴 Epithelial cell culture device capable of automatically conveying detection sample
CN113444643A (en) * 2021-05-24 2021-09-28 邵小文 Clinical laboratory is with bacterin research and development virus culture apparatus
CN113637587A (en) * 2021-09-02 2021-11-12 大连雅立峰生物制药有限公司 Full-automatic high-speed chick embryo dish changing and disinfecting linkage device

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