CN114748400A - Skin care product based on mesoporous silica nanoparticles and preparation method thereof - Google Patents
Skin care product based on mesoporous silica nanoparticles and preparation method thereof Download PDFInfo
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- CN114748400A CN114748400A CN202210338473.7A CN202210338473A CN114748400A CN 114748400 A CN114748400 A CN 114748400A CN 202210338473 A CN202210338473 A CN 202210338473A CN 114748400 A CN114748400 A CN 114748400A
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- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 title claims abstract description 75
- 239000000377 silicon dioxide Substances 0.000 title claims abstract description 27
- 239000002105 nanoparticle Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims description 12
- 239000000843 powder Substances 0.000 claims abstract description 36
- 239000004615 ingredient Substances 0.000 claims abstract description 26
- 239000003094 microcapsule Substances 0.000 claims abstract description 24
- 239000004965 Silica aerogel Substances 0.000 claims abstract description 21
- 235000015097 nutrients Nutrition 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 13
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 72
- 239000003921 oil Substances 0.000 claims description 34
- 235000019198 oils Nutrition 0.000 claims description 34
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 30
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 30
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 27
- 239000001140 aloe barbadensis leaf extract Substances 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims description 19
- 238000003756 stirring Methods 0.000 claims description 18
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 18
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims description 15
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 15
- 229930003268 Vitamin C Natural products 0.000 claims description 15
- 229930003427 Vitamin E Natural products 0.000 claims description 15
- 235000013793 astaxanthin Nutrition 0.000 claims description 15
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims description 15
- 229940022405 astaxanthin Drugs 0.000 claims description 15
- 239000001168 astaxanthin Substances 0.000 claims description 15
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 15
- 235000019154 vitamin C Nutrition 0.000 claims description 15
- 239000011718 vitamin C Substances 0.000 claims description 15
- 235000019165 vitamin E Nutrition 0.000 claims description 15
- 229940046009 vitamin E Drugs 0.000 claims description 15
- 239000011709 vitamin E Substances 0.000 claims description 15
- 238000005303 weighing Methods 0.000 claims description 12
- 108010020346 Polyglutamic Acid Proteins 0.000 claims description 10
- 235000021354 omega 7 monounsaturated fatty acids Nutrition 0.000 claims description 10
- 229920002643 polyglutamic acid Polymers 0.000 claims description 10
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 9
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 9
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical class CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 9
- 244000144725 Amygdalus communis Species 0.000 claims description 9
- 235000011437 Amygdalus communis Nutrition 0.000 claims description 9
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 9
- QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 claims description 9
- 108010087806 Carnosine Proteins 0.000 claims description 9
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 9
- CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 claims description 9
- 244000178231 Rosmarinus officinalis Species 0.000 claims description 9
- 235000011034 Rubus glaucus Nutrition 0.000 claims description 9
- 244000235659 Rubus idaeus Species 0.000 claims description 9
- 235000009122 Rubus idaeus Nutrition 0.000 claims description 9
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 9
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims description 9
- 239000008168 almond oil Substances 0.000 claims description 9
- 229960003237 betaine Drugs 0.000 claims description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 9
- 229940044199 carnosine Drugs 0.000 claims description 9
- CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 claims description 9
- 239000003995 emulsifying agent Substances 0.000 claims description 9
- 229940089161 ginsenoside Drugs 0.000 claims description 9
- 229930182494 ginsenoside Natural products 0.000 claims description 9
- 239000008169 grapeseed oil Substances 0.000 claims description 9
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 9
- 229920002674 hyaluronan Polymers 0.000 claims description 9
- 229960003160 hyaluronic acid Drugs 0.000 claims description 9
- 239000008213 purified water Substances 0.000 claims description 9
- 239000002904 solvent Substances 0.000 claims description 9
- 150000005846 sugar alcohols Polymers 0.000 claims description 9
- 235000002906 tartaric acid Nutrition 0.000 claims description 9
- 239000011975 tartaric acid Substances 0.000 claims description 9
- 229960003080 taurine Drugs 0.000 claims description 9
- 239000002562 thickening agent Substances 0.000 claims description 9
- 239000000341 volatile oil Substances 0.000 claims description 9
- 241000220317 Rosa Species 0.000 claims description 8
- 229940069521 aloe extract Drugs 0.000 claims description 8
- 240000008067 Cucumis sativus Species 0.000 claims description 7
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 claims description 7
- 235000020221 chamomile extract Nutrition 0.000 claims description 7
- 229940119217 chamomile extract Drugs 0.000 claims description 7
- 239000000783 alginic acid Substances 0.000 claims description 3
- 229920000615 alginic acid Polymers 0.000 claims description 3
- 235000010443 alginic acid Nutrition 0.000 claims description 3
- 229960001126 alginic acid Drugs 0.000 claims description 3
- 150000004781 alginic acids Chemical class 0.000 claims description 3
- 229940069638 aloe vera leaf extract Drugs 0.000 claims description 3
- 229940049638 carbomer homopolymer type c Drugs 0.000 claims description 3
- 229940043234 carbomer-940 Drugs 0.000 claims description 3
- 239000012071 phase Substances 0.000 claims 7
- 240000000950 Hippophae rhamnoides Species 0.000 claims 4
- 239000008346 aqueous phase Substances 0.000 claims 1
- 230000003020 moisturizing effect Effects 0.000 abstract description 5
- 235000012239 silicon dioxide Nutrition 0.000 abstract description 5
- 239000004964 aerogel Substances 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 230000002087 whitening effect Effects 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 3
- 229910052785 arsenic Inorganic materials 0.000 abstract description 2
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 abstract description 2
- 239000002775 capsule Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 abstract description 2
- 229910052753 mercury Inorganic materials 0.000 abstract description 2
- 206010033675 panniculitis Diseases 0.000 abstract description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 abstract description 2
- 230000037072 sun protection Effects 0.000 abstract description 2
- 241000229143 Hippophae Species 0.000 description 15
- 239000002537 cosmetic Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 4
- 230000036541 health Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 241001116389 Aloe Species 0.000 description 1
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 244000042664 Matricaria chamomilla Species 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 238000007792 addition Methods 0.000 description 1
- 239000003463 adsorbent Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 235000011399 aloe vera Nutrition 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000009499 grossing Methods 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/88—Polyamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a skin care product based on mesoporous silica nanoparticles, which comprises the following raw materials in parts by weight: 20-43 parts of water-phase ingredients, 15-35 parts of oil-phase ingredients, 5-14 parts of hydrophilic spherical mesoporous microencapsulated silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous microencapsulated silica aerogel powder and 5-13 parts of pearl powder. The invention is based on the spherical mesoporous microcapsule silicon dioxide aerogel powder, can bring effective nutrient components into a subcutaneous tissue layer to replace whitening materials such as arsenic, mercury, lead and the like, and fills moisturizing elements into the silicon dioxide nano microcapsule by a process to form a slow release capsule, so that the nutrient components are slowly released subcutaneously to play a skin care role for a long time, the specific surface area is very large, the damage of light rays of various wave bands to the skin surface can be effectively resisted, and the sun protection effect is achieved.
Description
Technical Field
The invention relates to the technical field of chemical products, in particular to a skin care product based on mesoporous silica nanoparticles and a preparation method thereof.
Background
The mesoporous silica nanoparticles have the characteristics of continuously adjustable uniform mesoporous aperture within the range of 2-50 nm, regular pore channels, stable skeleton structure, easily-modified inner and outer surfaces, no physiological toxicity and the like, and are very suitable for being used as carriers of drug molecules, and meanwhile, the mesoporous silica nanoparticles have huge specific surface area (>900m 2/g) and specific pore volume (>0.9cm 3/g).
In the field of cosmetics or health care products, functional cosmetics or health care products having whitening, spot removing, wrinkle removing and anti-aging effects are in the greatest demand. In order to realize the cosmetic and health care product with the functions, technicians in the industry research and develop a great number of preparation methods and formulas, but the effect is not very good.
In the prior art, the preparation method of the cosmetics or the care products is generally based on similar vaseline or talcum powder, but the problems of powder blocking, caking, allergy, heavy metal precipitation, nutrient floating on the skin and the like are easy to occur in the using process, so the prior art needs to be improved.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a skin care product based on mesoporous silica nanoparticles and a preparation method thereof.
In order to solve the technical problems, the invention is solved by the following technical scheme:
a skin care product based on mesoporous silica nanoparticles comprises the following raw materials in parts by weight:
20-43 parts of water-phase ingredients, 15-35 parts of oil-phase ingredients, 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder.
Preferably, the water-phase ingredients comprise the following raw materials in parts by weight:
2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe barbadensis leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine.
Preferably, the oil phase ingredients comprise the following raw materials in parts by weight:
10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol.
Preferably, the feed also comprises the following raw materials in parts by weight: 20-22 parts of carbomer 940 serving as an emulsifier and 9-12 parts of alginic acid serving as a thickening agent.
Preferably, the nutrient solution also comprises nutrient components, wherein the nutrient components are rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
In order to solve the technical problem, the invention is solved by the following technical scheme:
a preparation method of a skin care product based on mesoporous silica nanoparticles is characterized by comprising the following steps:
A. preparing water phase ingredients: weighing 2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe barbadensis leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine to prepare a mixture A;
B. preparing oil phase ingredients: weighing 10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol to prepare a mixture B;
C. Adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 50-90 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. sequentially adding 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture C is uniform, adding an emulsifier and a thickener, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. when the temperature of the mixture D is reduced to 40-60 ℃, adding the rest 2-6 parts of vitamin E, 2-6 parts of vitamin C, 1-8 parts of astaxanthin and 0.6-3 parts of aloe barbadensis leaf extract, and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product.
Preferably, steps A-F are all operated under an ultraviolet lamp having an intensity of 60-110uW/cm2。
Preferably, the nutrient component can be added in the step E, and the nutrient component is rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
Has the beneficial effects that: the invention aims to overcome the defects of the prior art and provide a cosmetic care product based on spherical mesoporous microcapsule silicon dioxide aerogel powder, which can bring effective nutrient components into a subcutaneous tissue layer to replace whitening materials such as arsenic, mercury, lead and the like, and pack moisture-keeping elements into silica nanometer microcapsules by a process to form a slow-release capsule, so that the nutrient components are slowly released subcutaneously, the skin-care effect is exerted for a long time, the specific surface area is large, the damage of light of each waveband on the skin surface can be effectively resisted, and the sun-proof effect is achieved. The spherical mesoporous microcapsule silicon dioxide aerogel powder is used as a carrier, a penetrating agent, an adsorbent, a smoothing agent and a viscosity control agent, so that the skin has moisturizing capability, and multiple moisturizing, moisturizing and mild care are brought to the delicate skin. Effectively improve the moisture of the skin, is beneficial to repairing the skin, improves the dryness of the skin, locks water for a long time and moistens the skin, and brings the moisture enjoyment to the skin.
In detail, the invention adopts spherical mesoporous microcapsule silicon dioxide aerogel powder as a carrier and also has the function of isolation and sun protection; the polyglutamic acid and the aloe extract are added, so that the moisturizing function is achieved; the omega 7 added into the seabuckthorn oil ensures that the care product has the anti-inflammatory effect; the spherical mesoporous microencapsulated silica aerogel powder also can slowly release the added nutrients.
Detailed Description
The present invention will be described in further detail with reference to examples, which are illustrative of the present invention and are not to be construed as being limited thereto.
In order to solve the technical problem, the invention is solved by the following technical scheme:
a skin care product based on mesoporous silica nanoparticles comprises the following raw materials in parts by weight:
20-43 parts of water-phase ingredients, 15-35 parts of oil-phase ingredients, 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder.
Preferably, the water-phase ingredients comprise the following raw materials in parts by weight:
2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe vera leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine.
Preferably, the oil phase ingredients comprise the following raw materials in parts by weight:
10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol.
Preferably, the feed also comprises the following raw materials in parts by weight: 20-22 parts of carbomer 940 serving as an emulsifier and 9-12 parts of alginic acid serving as a thickening agent.
Preferably, the nutrient solution also comprises nutrient components, wherein the nutrient components are rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
In order to solve the technical problem, the invention is solved by the following technical scheme:
a preparation method of a skin care product based on mesoporous silica nanoparticles is characterized by comprising the following steps:
A. preparing water-phase ingredients: weighing 2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe barbadensis leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine to prepare a mixture A;
B. Preparing oil phase ingredients: weighing 10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol to prepare a mixture B;
C. adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 50-90 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. sequentially adding 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture C is uniform, adding an emulsifier and a thickener, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. when the temperature of the mixture D is reduced to 40-60 ℃, adding the rest 2-6 parts of vitamin E, 2-6 parts of vitamin C, 1-8 parts of astaxanthin and 0.6-3 parts of aloe barbadensis leaf extract, and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product.
Preferably, said steps A-F are all operated under UV lamps having an intensity of 60-110uW/cm 2。
Preferably, a nutrient component can be added in the step E, and the nutrient component is rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
The first embodiment is as follows: rose whitening
A preparation method of a skin care product based on mesoporous silica nanoparticles comprises the following steps:
A. preparing water-phase ingredients: weighing 2 parts of vitamin E, 2 parts of vitamin C, 30 parts of purified water, 1 part of taurine, 0.6 part of aloe barbadensis leaf extract, 0.3 part of nicotinamide, 0.3 part of ginsenoside, 3 parts of hyaluronic acid, 0.3 part of polyglutamic acid, 0.1 part of betaine, 7 parts of solubilizer, 1 part of raspberry leaf extract, 1 part of tartaric acid and 0.1 part of carnosine to prepare a mixture A;
B. preparing oil phase ingredients: weighing 10 parts of sweet almond oil, 1 part of sea buckthorn oil, 2 parts of sea buckthorn oil, 7 parts of rosemary essential oil, 1 part of Jeao, 1 part of omega 7, 0.6 part of aloe barbadensis leaf extract, 0.01 part of grape seed oil, 1 part of astaxanthin, 3 parts of glycerol, 3 parts of butanediol, 0.1 part of hydrogenated lecithin, 0.1 part of 1, 2-hexanediol and 10 parts of polyhydric alcohol to prepare a mixture B;
C. adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 50 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. Sequentially adding 5 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture is uniform, adding an emulsifier and a thickening agent, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. when the temperature of the mixture D is reduced to 40-60 ℃, adding the rest 2 parts of vitamin E, 2 parts of vitamin C, 1 part of astaxanthin, 0.6 part of aloe barbadensis leaf extract and rose hydrosol, and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product. All the steps A to F are operated under an ultraviolet lamp with the intensity of 60W/cm2。
The second embodiment: chamomile for delaying senility
A preparation method of a skin care product based on mesoporous silica nanoparticles comprises the following steps:
A. preparing water phase ingredients: weighing 6 parts of vitamin E, 6 parts of vitamin C, 44 parts of purified water, 7 parts of taurine, 3 parts of aloe barbadensis leaf extract, 1 part of nicotinamide, 1 part of ginsenoside, 10 parts of hyaluronic acid, 1 part of polyglutamic acid, 0.3 part of betaine, 9 parts of solubilizer, 10 parts of raspberry leaf extract, 3 parts of tartaric acid and 0.5 part of carnosine to prepare a mixture A;
B. Preparing oil phase ingredients: weighing 13 parts of sweet almond oil, 8 parts of sea buckthorn oil, 5 parts of sea buckthorn oil, 9 parts of rosemary essential oil, 8 parts of Jeao, 6 parts of omega 7, 3 parts of aloe barbadensis leaf extract, 0.05 part of grape seed oil, 8 parts of astaxanthin, 10 parts of glycerol, 7 parts of butanediol, 0.4 part of hydrogenated lecithin, 0.5 part of 1, 2-hexanediol and 13 parts of polyhydric alcohol to prepare a mixture B;
C. adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 90 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. sequentially adding 14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 13 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture C is uniform, adding an emulsifier and a thickening agent, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. when the temperature of the mixture D is reduced to 40-60 ℃, adding the remaining 6 parts of vitamin E, 6 parts of vitamin C, 1-8 parts of astaxanthin, 3 parts of aloe barbadensis leaf extract and chamomile extract, and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product. All the steps A to F are operated under an ultraviolet lamp with the intensity of 110uW/cm 2。
Example three: aloe moisture-keeping agent
A preparation method of a skin care product based on mesoporous silica nanoparticles comprises the following steps:
A. preparing water phase ingredients: weighing 5 parts of vitamin E, 4 parts of vitamin C, 36 parts of purified water, 3 parts of taurine, 3 parts of aloe barbadensis leaf extract, 0.8 part of nicotinamide, 1 part of ginsenoside, 8 parts of hyaluronic acid, 1 part of polyglutamic acid, 0.2 part of betaine, 8 parts of solubilizer, 5 parts of raspberry leaf extract, 2 parts of tartaric acid and 0.15 part of carnosine to prepare a mixture A;
B. preparing oil phase ingredients: weighing 13 parts of sweet almond oil, 6 parts of sea buckthorn oil, 4 parts of sea buckthorn oil, 8 parts of rosemary essential oil, 4 parts of juao, 2 parts of omega 7, 2 parts of aloe barbadensis leaf extract, 0.04 part of grape seed oil, 5 parts of astaxanthin, 6 parts of glycerol, 6 parts of butanediol, 0.3 part of hydrogenated lecithin, 0.4 part of 1, 2-hexanediol and 12 parts of polyhydric alcohol to prepare a mixture B;
C. adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 70 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. sequentially adding 6 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 8 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 7 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture C is uniform, adding an emulsifier and a thickening agent, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. When the temperature of the mixture D is reduced to 40 ℃, adding the rest 4 parts of vitamin E, 5 parts of vitamin C, 6 parts of astaxanthin, 1 part of aloe vera leaf extract and aloe extract or/and cucumber extract and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product. All the steps A to F are operated under an ultraviolet lamp with the intensity of 90uW/cm2。
In addition, it should be noted that the specific embodiments described in the present specification may be different in terms of the parts, the shapes of the components, the names of the components, and the like. All equivalent or simple changes in the structure, characteristics and principles of the invention which are described in the patent conception are included in the protection scope of the invention. Various modifications, additions and substitutions for the specific embodiments described may be made by those skilled in the art without departing from the scope of the invention as defined in the accompanying claims.
Claims (8)
1. A skin care product based on mesoporous silica nanoparticles is characterized by comprising the following raw materials in parts by weight:
20-43 parts of water-phase ingredients, 15-35 parts of oil-phase ingredients, 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder.
2. The skin care product based on the mesoporous silica nanoparticles as claimed in claim 1, wherein the aqueous phase ingredients comprise the following raw materials in parts by weight:
2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe barbadensis leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine.
3. The skin care product based on the mesoporous silica nanoparticles as claimed in claim 1, wherein the oil phase ingredients comprise the following raw materials in parts by weight:
10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol.
4. The skin care product based on the mesoporous silica nanoparticles as claimed in claim 1, further comprising the following raw materials in parts by weight: 20-22 parts of carbomer 940 serving as an emulsifier and 9-12 parts of alginic acid serving as a thickening agent.
5. The method for preparing a skin care product based on mesoporous silica nanoparticles according to claim 1, further comprising a nutrient component, wherein the nutrient component is rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
6. A preparation method of a skin care product based on mesoporous silica nanoparticles is characterized by comprising the following steps:
A. preparing water phase ingredients: weighing 2-6 parts of vitamin E, 2-6 parts of vitamin C, 30-44 parts of purified water, 1-7 parts of taurine, 0.6-3 parts of aloe barbadensis leaf extract, 0.3-1 part of nicotinamide, 0.3-1 part of ginsenoside, 3-10 parts of hyaluronic acid, 0.3-1 part of polyglutamic acid, 0.1-0.3 part of betaine, 7-9 parts of solubilizer, 1-10 parts of raspberry leaf extract, 1-3 parts of tartaric acid and 0.1-0.5 part of carnosine to prepare a mixture A;
B. preparing oil phase ingredients: weighing 10-13 parts of sweet almond oil, 1-8 parts of sea buckthorn oil, 2-5 parts of sea buckthorn oil, 7-9 parts of rosemary essential oil, 1-8 parts of Kilo, 1-6 parts of omega 7, 0.6-3 parts of aloe barbadensis leaf extract, 0.01-0.05 part of grape seed oil, 1-8 parts of astaxanthin, 3-10 parts of glycerol, 3-7 parts of butanediol, 0.1-0.4 part of hydrogenated lecithin, 0.1-0.5 part of 1, 2-hexanediol and 10-13 parts of polyhydric alcohol to prepare a mixture B;
C. Adding the oil phase mixture B into the water phase mixture A at the following three temperature levels of 50-90 ℃, and stirring for 15 minutes until the mixture is uniform to prepare a mixture C;
D. sequentially adding 5-14 parts of hydrophilic spherical mesoporous micro-capsule silica aerogel powder, 5-14 parts of hydrophobic spherical mesoporous micro-capsule silica aerogel powder and 5-13 parts of pearl powder into the mixture C, continuing to emulsify, shear and stir for 8 minutes until the mixture is uniform, then adding an emulsifier and a thickening agent, and continuing to emulsify for 8 minutes to obtain a mixture D;
E. when the temperature of the mixture D is reduced to 40-60 ℃, adding the rest 2-6 parts of vitamin E, 2-6 parts of vitamin C, 1-8 parts of astaxanthin and 0.6-3 parts of aloe vera leaf extract, and uniformly stirring to obtain a mixture E;
F. and defoaming the mixture E to obtain a finished product.
7. The method of claim 6, wherein the steps A-F are performed under an ultraviolet lamp with an intensity of 60-110uW/cm2。
8. The method for preparing a skin care product based on mesoporous silica nanoparticles according to claim 6, wherein a nutrient component can be added in the step E, and the nutrient component is rose hydrosol, chamomile extract, aloe extract or/and cucumber extract.
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| WO2013124430A1 (en) * | 2012-02-23 | 2013-08-29 | L'oreal | Composition in the form of a foam constituted of an oil-in-water emulsion comprising hydrophobic silica aerogel particles |
| FR2989888A1 (en) * | 2012-04-26 | 2013-11-01 | Oreal | Cosmetic composition, useful in cosmetic/dermatological field for caring, protecting and/or making up keratin material such as bodily or facial skin and hair, comprises hydrophobic silica aerogel particles, and silane compound |
| US20150335536A1 (en) * | 2012-06-21 | 2015-11-26 | L'oreal | Translucent composition comprising silica aerogel particles |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
| CN113226261A (en) * | 2018-12-21 | 2021-08-06 | 欧莱雅 | Cosmetic composition with matte effect |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013124430A1 (en) * | 2012-02-23 | 2013-08-29 | L'oreal | Composition in the form of a foam constituted of an oil-in-water emulsion comprising hydrophobic silica aerogel particles |
| FR2989888A1 (en) * | 2012-04-26 | 2013-11-01 | Oreal | Cosmetic composition, useful in cosmetic/dermatological field for caring, protecting and/or making up keratin material such as bodily or facial skin and hair, comprises hydrophobic silica aerogel particles, and silane compound |
| US20150335536A1 (en) * | 2012-06-21 | 2015-11-26 | L'oreal | Translucent composition comprising silica aerogel particles |
| CN105411919A (en) * | 2015-12-01 | 2016-03-23 | 武汉光阴树生态科技有限公司 | Skin caring product made from roses and preparation method thereof |
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