CN114733586B - 一种微粒子流动聚焦装置及方法 - Google Patents

一种微粒子流动聚焦装置及方法 Download PDF

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Publication number
CN114733586B
CN114733586B CN202210228904.4A CN202210228904A CN114733586B CN 114733586 B CN114733586 B CN 114733586B CN 202210228904 A CN202210228904 A CN 202210228904A CN 114733586 B CN114733586 B CN 114733586B
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flow
sorting
focusing
flow channel
particles
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Chinese (zh)
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CN114733586A (zh
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陈华英
徐正
陈思远
陈震林
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Zhuhai Ontario Technology Co ltd
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Zhuhai Ontario Technology Co ltd
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Priority to PCT/CN2022/085184 priority patent/WO2023168775A1/fr
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202210228904.4A 2022-03-09 2022-03-09 一种微粒子流动聚焦装置及方法 Active CN114733586B (zh)

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CN202210228904.4A CN114733586B (zh) 2022-03-09 2022-03-09 一种微粒子流动聚焦装置及方法
PCT/CN2022/085184 WO2023168775A1 (fr) 2022-03-09 2022-04-02 Dispositif et procédé de focalisation d'écoulement de microparticules

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CN202210228904.4A CN114733586B (zh) 2022-03-09 2022-03-09 一种微粒子流动聚焦装置及方法

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CN114733586A CN114733586A (zh) 2022-07-12
CN114733586B true CN114733586B (zh) 2023-05-26

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CN (1) CN114733586B (fr)
WO (1) WO2023168775A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110496655A (zh) * 2019-07-26 2019-11-26 北京工业大学 一种基于微流控技术的肿瘤细胞检测芯片

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US20090052272A1 (en) * 2007-08-20 2009-02-26 Artann Laboratories, Inc. Ultrasonic stirring of liquids in small volumes
WO2012072822A1 (fr) * 2010-12-03 2012-06-07 Mindseeds Laboratories Srl Microanalyse d'une fonction cellulaire
US9597692B2 (en) * 2011-08-26 2017-03-21 Imec Micro-fluidic device for sorting particles, and methods for sorting particles
CN103191791B (zh) * 2013-03-01 2014-09-10 东南大学 生物微粒高通量分选和计数检测的集成芯片系统及应用
US9618520B2 (en) * 2013-04-25 2017-04-11 Vladislav B. Bergo Microarray compositions and methods of their use
CN103341372A (zh) * 2013-07-05 2013-10-09 西北工业大学 一种用于流式细胞仪的微流控芯片结构及其制作方法
CN104195028B (zh) * 2014-08-05 2017-07-25 深圳先进技术研究院 用于对特异性细胞进行筛选的微流控芯片及细胞筛选方法
US10488321B2 (en) * 2015-03-19 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Devices and methods for high-throughput single cell and biomolecule analysis and retrieval in a microfluidic chip
JP2017219479A (ja) * 2016-06-09 2017-12-14 住友電気工業株式会社 微小粒子計測装置及び分析方法
US10391493B2 (en) * 2017-08-29 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
CN108034586B (zh) * 2018-01-02 2023-09-22 清华大学深圳研究生院 一种用于单细胞捕捉和培养的微流控芯片
CN109943475A (zh) * 2019-04-12 2019-06-28 广西医科大学第一附属医院 一种微流控分选芯片及其分选系统
CN111019998A (zh) * 2019-12-26 2020-04-17 广东省医疗器械研究所 一种用于异质循环肿瘤细胞即时检测的方法及装置
CN111733074B (zh) * 2020-07-30 2020-12-04 首都医科大学附属北京友谊医院 用于循环肿瘤细胞高通量磁力分选的微流控芯片及其系统

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110496655A (zh) * 2019-07-26 2019-11-26 北京工业大学 一种基于微流控技术的肿瘤细胞检测芯片

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CN114733586A (zh) 2022-07-12
WO2023168775A1 (fr) 2023-09-14

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