CN114732023B - Insecticidal composition containing Oxazosulfyl and chlorantraniliprole and application thereof - Google Patents
Insecticidal composition containing Oxazosulfyl and chlorantraniliprole and application thereof Download PDFInfo
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- CN114732023B CN114732023B CN202210578028.8A CN202210578028A CN114732023B CN 114732023 B CN114732023 B CN 114732023B CN 202210578028 A CN202210578028 A CN 202210578028A CN 114732023 B CN114732023 B CN 114732023B
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- Prior art keywords
- chlorantraniliprole
- oxazosulfyl
- mass ratio
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- synergistic
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- 239000005886 Chlorantraniliprole Substances 0.000 title claims abstract description 44
- 239000000203 mixture Substances 0.000 title claims abstract description 37
- PSOVNZZNOMJUBI-UHFFFAOYSA-N chlorantraniliprole Chemical compound CNC(=O)C1=CC(Cl)=CC(C)=C1NC(=O)C1=CC(Br)=NN1C1=NC=CC=C1Cl PSOVNZZNOMJUBI-UHFFFAOYSA-N 0.000 title claims abstract description 35
- PTQBEFQWTBZMED-UHFFFAOYSA-N 2-(3-ethylsulfonylpyridin-2-yl)-5-(trifluoromethylsulfonyl)-1,3-benzoxazole Chemical group CCS(=O)(=O)C1=CC=CN=C1C1=NC2=CC(S(=O)(=O)C(F)(F)F)=CC=C2O1 PTQBEFQWTBZMED-UHFFFAOYSA-N 0.000 title claims abstract description 32
- 230000000749 insecticidal effect Effects 0.000 title abstract description 8
- 239000004480 active ingredient Substances 0.000 claims abstract description 17
- 230000002195 synergetic effect Effects 0.000 claims abstract description 11
- 241001477931 Mythimna unipuncta Species 0.000 claims description 11
- 239000002270 dispersing agent Substances 0.000 claims description 8
- 239000000080 wetting agent Substances 0.000 claims description 8
- 239000004562 water dispersible granule Substances 0.000 claims description 7
- 239000004563 wettable powder Substances 0.000 claims description 7
- 239000002917 insecticide Substances 0.000 claims description 5
- 239000002671 adjuvant Substances 0.000 claims description 4
- 239000002518 antifoaming agent Substances 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 4
- -1 synergists Substances 0.000 claims description 4
- 239000002562 thickening agent Substances 0.000 claims description 4
- 239000007798 antifreeze agent Substances 0.000 claims description 2
- 239000000969 carrier Substances 0.000 claims description 2
- 239000007884 disintegrant Substances 0.000 claims description 2
- 239000004495 emulsifiable concentrate Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 239000000839 emulsion Substances 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000004530 micro-emulsion Substances 0.000 claims description 2
- 239000003094 microcapsule Substances 0.000 claims description 2
- 239000003755 preservative agent Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 239000003381 stabilizer Substances 0.000 claims description 2
- 239000000725 suspension Substances 0.000 claims description 2
- 241000607479 Yersinia pestis Species 0.000 abstract description 11
- 238000012360 testing method Methods 0.000 description 20
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- 239000000575 pesticide Substances 0.000 description 12
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- PXBFMLJZNCDSMP-UHFFFAOYSA-N 2-Aminobenzamide Chemical compound NC(=O)C1=CC=CC=C1N PXBFMLJZNCDSMP-UHFFFAOYSA-N 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- 241000353522 Earias insulana Species 0.000 description 2
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- 230000000996 additive effect Effects 0.000 description 2
- 230000008485 antagonism Effects 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 230000007750 drug combination effect Effects 0.000 description 2
- 235000012055 fruits and vegetables Nutrition 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000008194 pharmaceutical composition Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
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- 210000002784 stomach Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- BCMCBBGGLRIHSE-UHFFFAOYSA-N 1,3-benzoxazole Chemical compound C1=CC=C2OC=NC2=C1 BCMCBBGGLRIHSE-UHFFFAOYSA-N 0.000 description 1
- LWEAHXKXKDCSIE-UHFFFAOYSA-M 2,3-di(propan-2-yl)naphthalene-1-sulfonate Chemical compound C1=CC=C2C(S([O-])(=O)=O)=C(C(C)C)C(C(C)C)=CC2=C1 LWEAHXKXKDCSIE-UHFFFAOYSA-M 0.000 description 1
- RWNISPVLLBWJBU-UHFFFAOYSA-N 2-sulfonyl-1h-pyridine Chemical group O=S(=O)=C1C=CC=CN1 RWNISPVLLBWJBU-UHFFFAOYSA-N 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 239000005995 Aluminium silicate Substances 0.000 description 1
- 241001124076 Aphididae Species 0.000 description 1
- 235000007319 Avena orientalis Nutrition 0.000 description 1
- 241000209763 Avena sativa Species 0.000 description 1
- 235000007558 Avena sp Nutrition 0.000 description 1
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 1
- 235000014698 Brassica juncea var multisecta Nutrition 0.000 description 1
- 235000006008 Brassica napus var napus Nutrition 0.000 description 1
- 240000000385 Brassica napus var. napus Species 0.000 description 1
- 235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
- 241001414720 Cicadellidae Species 0.000 description 1
- 241000254173 Coleoptera Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241001466042 Fulgoromorpha Species 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241000219146 Gossypium Species 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 235000004431 Linum usitatissimum Nutrition 0.000 description 1
- 240000006240 Linum usitatissimum Species 0.000 description 1
- 241001494184 Myxozoa Species 0.000 description 1
- 241000256259 Noctuidae Species 0.000 description 1
- 241000255969 Pieris brassicae Species 0.000 description 1
- 240000000111 Saccharum officinarum Species 0.000 description 1
- 235000007201 Saccharum officinarum Nutrition 0.000 description 1
- 241000209056 Secale Species 0.000 description 1
- 235000007238 Secale cereale Nutrition 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 244000062793 Sorghum vulgare Species 0.000 description 1
- 241000985245 Spodoptera litura Species 0.000 description 1
- 235000021536 Sugar beet Nutrition 0.000 description 1
- 241001414989 Thysanoptera Species 0.000 description 1
- 241000255901 Tortricidae Species 0.000 description 1
- 235000019714 Triticale Nutrition 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 235000012211 aluminium silicate Nutrition 0.000 description 1
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229910001424 calcium ion Inorganic materials 0.000 description 1
- 229920005551 calcium lignosulfonate Polymers 0.000 description 1
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- GVGUFUZHNYFZLC-UHFFFAOYSA-N dodecyl benzenesulfonate;sodium Chemical compound [Na].CCCCCCCCCCCCOS(=O)(=O)C1=CC=CC=C1 GVGUFUZHNYFZLC-UHFFFAOYSA-N 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- CXEGAUYXQAKHKJ-NSBHKLITSA-N emamectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](NC)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 CXEGAUYXQAKHKJ-NSBHKLITSA-N 0.000 description 1
- 230000005669 field effect Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 229940095686 granule product Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 235000019713 millet Nutrition 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 102000042094 ryanodine receptor (TC 1.A.3.1) family Human genes 0.000 description 1
- 108091052345 ryanodine receptor (TC 1.A.3.1) family Proteins 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 229940080264 sodium dodecylbenzenesulfonate Drugs 0.000 description 1
- 229920005552 sodium lignosulfonate Polymers 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
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- 238000002723 toxicity assay Methods 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/76—1,3-Oxazoles; Hydrogenated 1,3-oxazoles
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention provides an insecticidal composition containing Oxazosulfyl and chlorantraniliprole, wherein the active ingredients comprise Oxazosulfyl and chlorantraniliprole, and the mass ratio of Oxazosulfyl to chlorantraniliprole is (1); the composition has obvious synergistic effect and can be used for preventing and controlling crop pests.
Description
Technical Field
The invention relates to the technical field of pesticides, in particular to an insecticidal composition containing Oxazosulfyl and chlorantraniliprole and application thereof.
Background
Oxazosulfyl is an insecticide developed by Sumitomo chemical Co., ltd., japan, and has the development code No. S-1587. The oxasulfenyl is also a first benzoxazole pesticide, the molecule of the oxasulfenyl contains a sulfonyl pyridine fragment, and the chemical structure is as follows:oxazosulfyl has good control effect on lepidoptera, coleoptera and diptera rice pests and also has good control effect on part of mites.
Chlorantraniliprole, english name: chlorantraniliprole, belonging to the group of anthranilamide insecticides. The chemical structure is as follows:the chlorantraniliprole pesticide is a broad-spectrum pesticide, is mainly used for preventing and controlling lepidoptera pests (having good control effect on noctuidae, stem borer family, moth-eating family, leaf roller moth family, pink moth family, plutella xylostella family and the like) of various crops, and also has better prevention effect on other pests. The mechanism of action is the combination of chlorantraniliprole and a ryanodine receptor, which causes the uncontrolled release and the loss of endogenous calcium ions of cells and leads the contraction function of muscle cells to be difficult to continue. The action modes are stomach toxicity and contact toxicity, and stomach toxicity is the main action mode. Can penetrate into plant body through the surface of stem and leaf, and can be absorbed by root and moved in xylem.
The synergistic compounding of the pesticide is an effective measure for expanding a control spectrum, improving the control effect and reducing the pesticide cost of farmers, and the applicant carries out deep research on the mixed preparation of Oxazosulfyl and chlorantraniliprole, and finds that the mixed preparation of the chlorantraniliprole and the emamectin benzoate has strong synergistic effect; can effectively slow down the generation of drug resistance of pests, reduce the dosage of active ingredients and lighten environmental pollution.
Disclosure of Invention
The invention aims to provide a synergistic insecticidal composition which can effectively slow down the generation of drug resistance of pests, reduce the dosage of active ingredients and reduce environmental pollution.
The specific technical scheme is as follows:
an insecticidal composition containing Oxazosulfyl and chlorantraniliprole is characterized in that active ingredients comprise Oxazosulfyl and chlorantraniliprole, and the mass ratio of Oxazosulfyl to chlorantraniliprole is 1. The preferable mass ratio of Oxazosulfyl to chlorantraniliprole is 1. The preferable mass ratio of Oxazosulfyl to chlorantraniliprole is 1. The preferable mass ratio of Oxazosulfyl to chlorantraniliprole is 1. The mass ratio of Oxazosulfyl to chlorantraniliprole is 1.
In some embodiments, the present invention provides an insecticidal formulation comprising the insecticidal combination of claim and an adjuvant.
In some embodiments, the formulation is in the form of emulsifiable concentrate, wettable powder, suspension, granules, water dispersible granules, microemulsion, aqueous emulsion, microcapsules.
The composition or preparation of the present invention contains, in addition to the active ingredients Oxazosulfyl and chlorantraniliprole, adjuvants generally used in agricultural chemicals, such as wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreezes, antifoaming agents, solvents, preservatives, stabilizers, synergists, carriers, and the like, and can be added as appropriate according to the needs of the preparation, and may be changed depending on the circumstances, and is not particularly limited.
The composition comprises the following components in percentage by weight when prepared into wettable powder: 1-75% of active ingredient, 1-10% of dispersing agent, 1-10% of wetting agent and the balance of filler to 100%.
The active ingredients, the dispersant, the wetting agent and the filler are mixed, uniformly mixed in a mixing cylinder, crushed by a jet mill and uniformly mixed, and the wettable powder product of the composition can be prepared.
When the composition is prepared into water dispersible granules, the composition comprises the following components in percentage by weight: 1-75% of active ingredient, 1-10% of dispersing agent, 1-8% of wetting agent, 1-5% of disintegrating agent, 1-5% of binding agent and the balance of filler to 100%.
The active ingredients, the dispersing agent, the wetting agent, the disintegrating agent, the filler and the like are crushed by airflow to obtain the required particle size, and other auxiliary agents such as a binder and the like are added to obtain the granulating material. And (3) quantitatively feeding the materials into a fluidized bed granulation dryer, and granulating and drying to obtain the water dispersible granule product of the composition.
The composition is prepared into a suspending agent and comprises the following components in percentage by weight: 1-75% of active ingredient, 1-10% of dispersant, 1-10% of wetting agent, 0.1-3% of defoaming agent, 0.1-3% of thickening agent, 0.1-5% of antifreeze agent and deionized water for making up 100%.
The dispersant, the wetting agent, the defoaming agent, the thickening agent and the antifreeze in the formula materials are sheared and mixed uniformly at a high speed, the active ingredients are added, and the mixture is ball-milled in a ball mill for 2 to 3 hours to ensure that the particle size of particles is below 5 mu m, so that the suspending agent product of the composition is prepared.
The treatment of plants and plant parts with the compositions or preparations according to the invention comprising Oxazosulfyl and chlorantraniliprole can be carried out directly or by applying the compositions or preparations to their surroundings, habitat or storage area using customary treatment methods, for example by dipping, spraying, misting and seed treatment.
The present invention is primarily directed to crops such as corn, soybean, cotton, canola, rice, wheat, sugar beet, sugarcane, oat, rye, barley, millet, triticale, flax, vines, and various fruits and vegetables from various plant taxa, horticultural and forest crops; an ornamental plant.
In some embodiments, the invention provides the use of a pesticidal composition comprising Oxazosulfyl and chlorantraniliprole for controlling pests of crops and fruits and vegetables. Preferably, the insects are diamondback moths, armyworms, plant hoppers, leafhoppers, aphids, stem borers, thrips, cabbage caterpillars, prodenia lituras and the like.
The beneficial technical effects are as follows:
1. the compound has obvious synergistic effect, improves the control effect and prolongs the service life of the medicament; 2. the prevention and treatment spectrum is expanded; 3. the two active ingredients are compounded, so that the use amount of the pesticide is reduced, the cost is reduced, and the pollution to the environment is reduced.
Detailed Description
The present invention will be further explained with reference to specific embodiments.
EXAMPLE 1 determination of the indoor toxicity of Agents on Plutella xylostella
And (3) testing pests: cabbage diamondback moth. Collected in the field, and used for bioassay after indoor breeding for 4 generations by using fresh cabbage leaves. During the test, healthy 3-instar larvae with consistent sizes are selected as test insects.
The test method comprises the following steps: the leaf soaking method is adopted. On the basis of a pre-test, 7 medicaments with different concentration gradients are arranged. Beating fresh cabbage into leaf dishes by using a puncher with the diameter of 20mm, soaking the leaf dishes in test liquid medicine for 10s, taking out and drying the leaf dishes, putting the leaf dishes into culture dishes padded with moisturizing filter paper, putting 5 leaf dishes into each dish, naturally drying, selecting starved test insects for 4 hours into the culture dishes, and repeating the steps of treating for 4 times for 15 heads of each dish. After the treatment is finished, the container cover is covered, the container cover is placed in an artificial climate chamber for feeding, the death condition of the insect mouth is checked after 48 hours, and the death judgment standard of the tested insects is that the death is counted by the condition that the tip of the writing brush lightly contacts the tested insects and does not react. Calculating according to analysis software to obtain an LC50 value; and evaluating the drug combination effect. The combined action mode adopts a method which is proposed in 1960 by Sun Yunpei et al and calculates the combined toxicity of the mixture through the toxicity index, namely a co-toxicity coefficient (CTC) method.
The co-toxicity coefficient is calculated as follows:
actually measured virulence index (ATI) = (standard medicament LC 50/test medicament LC 50) × 100
Theoretical virulence index (TTI) = a medicament ATI x percentage of a in the mixture + B medicament ATI x percentage of B in the mixture
Co-toxicity coefficient (CTC) = (ATI/TTI mixed dose) × 100
When the CTC is less than or equal to 80, the composition shows antagonism, when the CTC is more than 80 and less than 120, the composition shows additive action, and when the CTC is more than or equal to 120, the composition shows synergistic action.
And (3) testing results: as can be seen from Table 1, the combination of Oxazosulfyl and chlorantraniliprole shows two different combined effects of addition and synergy for diamondback moth. When the mass ratio of Oxazosulfyl to chlorantraniliprole is 1. When the mass ratio of Oxazosulfyl to chlorantraniliprole is 1-15. Particularly, when the mass ratio of Oxazosulfyl to chlorantraniliprole is 5. When the composition shows synergism, the dosage of active ingredients can be effectively reduced, the generation of pesticide resistance is slowed down, and the environmental pollution is alleviated.
Table 1: combined action determination result of compound medicament on diamondback moth
EXAMPLE 2 agent indoor toxicity assay for myxozoa
And (3) testing pests: sticking insects; collecting 5-6 instar armyworm larvae in a field, and feeding indoors until the armyworm larvae lay eggs. Hatched larvae of the F1 generation were reared to 3 instar larvae as test insects.
The test method comprises the following steps: the leaf soaking method is adopted. On the basis of the preliminary test, 7 agents with different concentration gradients are set. Soaking the corn leaves (without spraying any insecticide) in the liquid medicine to be tested for 10s, and then naturally airing the corn leaves on a culture dish. And (3) putting a proper amount of treated leaves into each culture dish, inoculating 10 uniform armyworm larvae of 3 years old, repeating for 4 times at each concentration, sealing with a sealing film, and putting into an incubator for feeding. After 72h of processing, the death condition of the test insects is checked, and an LC50 value is calculated according to analysis software according to the death standard that the larvae can not climb normally; and evaluating the drug combination effect. The combined action mode adopts a method which is proposed in 1960 by Sun Yunpei et al and calculates the combined toxicity of the mixture through a toxicity index, namely a co-toxicity coefficient (CTC) method.
The co-toxicity coefficient is calculated as follows:
actually measured virulence index (ATI) = (standard medicament LC 50/test medicament LC 50) × 100
Theoretical virulence index (TTI) = a medicament ATI x percentage of a in the mixture + B medicament ATI x percentage of B in the mixture
Cotoxicity coefficient (CTC) = (ATI/TTI) x 100
When the CTC is less than or equal to 80, the composition shows antagonism, when the CTC is more than 80 and less than 120, the composition shows additive action, and when the CTC is more than or equal to 120, the composition shows synergistic action.
And (3) testing results: as can be seen from Table 2, the combination of Oxazosulfyl and chlorantraniliprole showed two different combined effects of addition and synergism on armyworm. When the mass ratio of Oxazosulfyl to chlorantraniliprole is 1. When the mass ratio of Oxazosulfyl to chlorantraniliprole is 5. Particularly, when the mass ratio of Oxazosulfyl to chlorantraniliprole is 1. When the composition shows synergism, the dosage of active ingredients can be effectively reduced, the generation of pesticide resistance is slowed down, and the environmental pollution is reduced.
Table 1: determination result of combined effect of compound medicament on armyworm
Example 3 formulation example
20 percent of Oxa-chlorantraniliprole wettable powder, which comprises the following components in percentage by weight:
oxazosulfyl 10%, chlorantraniliprole 10%, sodium lignosulphonate 3%, nekal BX2%, white carbon black 2%, and kaolin for 100%.
18% oxa-chlorantraniliprole suspension concentrate comprising the following ingredients in weight percent:
15% of Oxazosulfyl, 3% of chlorantraniliprole, 4% of sodium dodecyl benzene sulfonate, 425% of Morwet D, 0.5% of an organic silicon defoamer, 1% of ethylene glycol, 2% of xanthan gum, 1% of magnesium aluminum silicate, 1.5% of sodium benzoate and deionized water for making up 100%.
30 percent of Oxa-chlorantraniliprole water dispersible granules, which comprise the following components in percentage by weight:
5% of Oxazosulfyl, 25% of chlorantraniliprole, 4894% of TERSPERSE, 3% of calcium lignosulfonate, 2% of ammonium sulfate, 1% of sodium carboxymethylcellulose and 100% of bentonite.
Example 4 field control of cabbage diamondback moth with the pharmaceutical formulation
Test objects: cabbage diamondback moth
The test method comprises the following steps: when the pesticide is applied, the cabbage is in a vigorous state, the generation amount of diamondback moths is large, and the cabbage is mainly provided with low-age larvae. A random block arrangement was used, with a cell area of 50m2, with 4 replicates per treatment. The population base number of insects is investigated before the medicine, and the control effect is investigated 14 days after the medicine. Randomly marking 5 points in each district, investigating 5 plants in each point, investigating the number of pests on leaves of each cabbage, counting the number of live pests, and calculating the reduction rate of insect population and the control effect.
And (3) testing results: as is clear from Table 3, 20% of the Oxa-chlorantraniliprole wettable powder prepared by the present invention, 18% of Oxa-chlorantraniliprole suspending agent and 30% of Oxa-chlorantraniliprole water dispersible granule the field effect against cabbage diamondback moth was 80% or more, particularly 90% or more, when the amount thereof was 2.5 g/mu, when the field amount of the active ingredient was 1.5 to 2.5 g/mu. The compound pesticide has excellent control effect on cabbage diamondback moths, and is safe for cabbage crops through field observation.
Table 3: the medicinal preparation has field control effect on cabbage diamondback moth
EXAMPLE 5 field control of corn armyworm with the pharmaceutical formulation
Test object(s): corn armyworm
The test method comprises the following steps: when the pesticide is applied, field test insects are in the full growth period during the test, and the low-age larvae are mainly used. A random block arrangement was used, with a cell area of 25m2, with 4 replicates per treatment. Sampling is carried out at 5 points in each cell, each point is 1m < 2 >, the population base number is investigated before the medicine is taken, and the control effect is investigated 7 days after the medicine is taken. Counting the number of live insects, calculating the reduction rate of insect population and preventing and treating effect.
And (3) testing results: as is apparent from Table 3, the 20% Oxa-chlorantraniliprole wettable powder prepared by the present invention, 18% Oxa-chlorantraniliprole suspending agent and 30% Oxa-chlorantraniliprole water dispersible granule when the field use amount of the active ingredients was 1.0 to 2.0 g/acre had an excellent control effect on corn armyworm of 80% or more, and was safe for corn crops in field observation.
Table 4: the medicinal preparation has field control effect on corn armyworm
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same.
Claims (4)
1. The synergistic application of the insecticide for preventing and controlling armyworms is characterized in that active ingredients comprise Oxazosulfyl and chlorantraniliprole, and the mass ratio of the Oxazosulfyl to the chlorantraniliprole is 1: 1-5: 1.
2. Synergistic use according to claim 1, characterized in that the insecticide comprises adjuvants.
3. The synergistic use according to claim 2, wherein the adjuvants are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, antifoaming agents, solvents, preservatives, stabilizers, synergists, carriers.
4. The synergistic use as claimed in claim 3, wherein the formulation is an emulsifiable concentrate, a wettable powder, a suspension, a granule, a water dispersible granule, a microemulsion, an aqueous emulsion or a microcapsule.
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Denomination of invention: A insecticidal composition containing Oxazosulfyl and Chlorfenamide and its application Granted publication date: 20230418 Pledgee: China Merchants Bank Limited by Share Ltd. Hefei branch Pledgor: ANHUI ZHONGBANG BIOLOGICAL ENGINEERING Co.,Ltd. Registration number: Y2024980011410 |