CN111937888A - Insecticidal composition and application thereof - Google Patents
Insecticidal composition and application thereof Download PDFInfo
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- CN111937888A CN111937888A CN202010847847.9A CN202010847847A CN111937888A CN 111937888 A CN111937888 A CN 111937888A CN 202010847847 A CN202010847847 A CN 202010847847A CN 111937888 A CN111937888 A CN 111937888A
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- pyridalyl
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/58—1,2-Diazines; Hydrogenated 1,2-diazines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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Abstract
The invention provides an insecticidal composition and application thereof, belonging to the field of insecticides, wherein the insecticidal composition can effectively expand an insecticidal spectrum, improve the control effect, prolong the application suitable period, reduce the dosage, reduce the phytotoxicity, reduce the residue and delay the occurrence of drug resistance and drug resistance of pests after selecting active ingredients pyridaben and pyridalyl for compounding. The insecticidal composition comprises effective components and auxiliary components, wherein the effective components comprise pyridaben and pyridalyl in a weight ratio of 40:1-1:40, the effective components of the pyridaben and the pyridalyl in a weight percentage of 1-80%, the auxiliary components comprise a carrier and an auxiliary agent, the carrier is one or more of water, a solvent or a filler, and the auxiliary agent at least comprises a surfactant. The insecticidal composition can effectively control trialeurodes vaporariorum, leafhopper and aphid, and also has good control effect on lepidoptera pests such as asparagus caterpillar, diamond back moth, homoptera and coleoptera pests.
Description
Technical Field
The invention belongs to the field of pesticides, particularly relates to the field of insecticides, and particularly relates to an insecticidal composition and application thereof.
Background
In the agricultural production process, the application of chemical agents is the most effective means for controlling plant diseases and insect pests, but the chemical control of pests is most likely to cause the problem of pest resistance to drugs, and the long-term, continuous and high-dose application of a single chemical agent is likely to cause a series of problems such as drug residues and environmental pollution. One of the methods for solving the problems is to develop a new pesticide, but the development cost of a new active ingredient is high, the development period is long, the speed of generating resistance by pests can not be kept up to ever, and the new active ingredient is difficult to be really applied to actual production.
The pyridaben is a respiratory system inhibitor, is a novel high-efficiency, broad-spectrum and low-toxicity acaricidal insecticide, and mainly plays a role in killing mites and insects by inhibiting the synthesis of glutamate dehydrogenase in muscle tissues, nerve tissues and chromosome I of an electron transfer system. Can be used for preventing and treating various phytophagous harmful mites. The insecticidal composition has good effect on the whole growth period of mites, namely eggs, young mites, nymphs and adult mites, has obvious quick killing effect on adult mites in the moving period, and can effectively prevent and control the spider mites, rust mites, spider mites, pear psyllids, aphids, whiteflies and the like.
The trifluromethyl pyriproxyfen pesticide has a unique chemical structure, has a different action mechanism from common pesticides, and is mainly used for preventing and treating lepidoptera larvae which are harmful crops and cabbage moths, and has a good prevention and treatment effect. The control effect on beet armyworm is better. It also has excellent control effect on pests with resistance to the existing pesticide. While it has minimal impact on many beneficial arthropods.
Based on the problems in the prior art, through reasonable compounding or blending of different insecticides, the insecticidal composition has the characteristics of expanding insecticidal spectrum, improving control effect, prolonging the application period, reducing dosage, reducing phytotoxicity, reducing residues, delaying the occurrence and development of drug resistance and the like, and is an important means for comprehensively controlling plant diseases and insect pests. The pyridaben and pyridalyl have certain defects and limitations when used singly. At present, no compound medicine of the two is available, and the effect of the combination of other insecticides is not ideal.
Disclosure of Invention
The invention aims to provide an insecticidal composition and application thereof, wherein after the pyridaben and pyridalyl which are effective components are selected and reasonably compounded, the insecticidal spectrum can be expanded, the control effect can be improved, the application period can be prolonged, the dosage can be reduced, the phytotoxicity can be reduced, the residue can be reduced, and the occurrence of drug resistance and drug resistance of pests can be delayed.
In order to achieve the purpose, the invention adopts the technical scheme that:
the insecticidal composition comprises effective components and auxiliary components, wherein the effective components comprise pyridaben and pyridalyl in a weight ratio of 40:1-1: 40.
Preferably, the weight ratio of the active ingredients of the pyridaben to the pyridalyl is 8:1-1: 6.
Preferably, the weight ratio of the active ingredients of the pyridaben to the pyridalyl is 6:1-1: 6.
Preferably, the weight ratio of the active ingredients pyridaben to pyridalyl is 1:1 or 1:2 or 1: 4.
Preferably, the weight percentage of the active ingredients of the pyridaben and the pyridalyl is 1 to 80 percent.
Preferably, the auxiliary components comprise a carrier and an auxiliary agent, the carrier is one or more of water, a solvent or a filler, and the auxiliary agent at least comprises a surfactant.
The water is deionized water; the solvent is selected from one or a mixture of more of N, N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octyl pyrrolidone, ethanolamine, triethanolamine, isopropylamine, N-methyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol butyl ether, ethanolamine, ethyl acetate or acetonitrile; the filler is selected from one or a mixture of more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate.
Preferably, the surfactant is selected from one or more of an emulsifier, a dispersant, a wetting agent or a penetrant; the auxiliary agent also comprises one or more of an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent and a defoaming agent.
The emulsifier is selected from OP series phosphate (nonylphenol polyoxyethylene ether phosphate), 600# phosphate (phenylphenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate, magnesium alkyldiphenyl ether disulfonate, triethanolamine salt, Nostoc 400# (benzyldimethylphenol polyoxyethylene ether), Nostoc 700# (alkylphenol formaldehyde resin polyoxyethylene ether), Ningru 36# (phenethylphenol formaldehyde resin polyoxyethylene ether), agricultural cream 1600# (phenethyl phenol polyoxyethylene polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), BY series (castor oil polyoxyethylene ether), agricultural cream 33# (alkylaryl polyoxyethylene polyoxypropylene ether), span series (sorbitan monostearate), Tween series (sorbitan fatty acid ester polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether).
The dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, calcium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether or glycerin fatty acid ester polyoxyethylene ether.
The wetting agent is selected from one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, saponin powder, silkworm excrement or soapberry powder.
The penetrating agent is selected from one or a mixture of more of penetrating agent JFC (fatty alcohol-polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone or organic silicon.
The antifreezing agent is a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea.
The thickening agent is selected from one or a mixture of more of gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, xanthan gum, bentonite, silicon dioxide or magnesium aluminum silicate.
The stabilizer is selected from one or more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate or triphenyl phosphate.
The disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate.
The defoaming agent is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds.
Preferably, the dosage form of the insecticidal composition is one of wettable powder, water dispersible granules, water suspending agent or dispersible oil suspending agent.
The invention also provides an application of the insecticidal composition in any one of the preferable technical schemes, which is used for controlling field hemiptera pests and lepidoptera pests, wherein the hemiptera pests comprise trialeurodes vaporariorum and leafhopper, and the lepidoptera pests comprise asparagus caterpillars and diamond back moths.
Preferably, the pesticide composition also comprises the pesticide composition for controlling field aphids.
Compared with the prior art, the invention has the advantages and positive effects that:
1. the insecticidal composition provided by the invention has obvious synergistic effect, the interaction among the activities of the components is not simple superposition but obvious synergistic effect, and the insecticidal composition has good quick action, high knockdown speed and good effect on pests, eggs, larvae and nymphs;
2. the insecticidal composition provided by the invention has different action mechanisms of the active ingredients, increases the action sites, is favorable for delaying the generation of target drug resistance, prolongs the service life of the compound, expands the insecticidal spectrum, has high activity on trialeurodes vaporariorum and leafhopper, and has good control effect on aphids, lepidoptera pests such as asparagus caterpillars, diamond back moths, homoptera and coleoptera pests. At present, no single active ingredient in the composition of the invention is registered for controlling trialeurodes vaporariorum;
3. the insecticidal composition provided by the invention has the advantages that the pesticide effect is obviously improved, the field dosage of the active ingredients is reduced, the production and use cost is reduced, the preparation residue is less, and the pollution of pesticide residue to the environment is reduced;
4. the insecticidal composition provided by the invention is safe to human and livestock and has good environmental compatibility;
5. the insecticidal composition provided by the invention is low in cost, simple in preparation process and suitable for large-area popularization and use.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the invention provides an insecticidal composition and application thereof, wherein the insecticidal composition comprises effective components and auxiliary components, the effective components comprise pyridaben and pyridalyl, and the weight ratio of the pyridaben to the pyridalyl is 40:1-1: 40. The insecticidal composition provided in this example mainly contains pyridaben and pyridalyl as active ingredients, and in addition, contains auxiliary ingredients for forming the composition. In order to achieve the purposes of expanding the insecticidal spectrum and delaying the drug resistance and drug fastness of pests, the composition reduces the dosage according to different action mechanisms of compound components, is highly safe to field crops, and simultaneously reduces pesticide residue and environmental pollution.
In order to achieve the above objects and function, in a preferred embodiment of the present invention, the weight ratio of the active ingredients pyridaben and pyridalyl is set to 8:1 to 1: 6. Within the above range, the insecticidal effect of the active ingredients is shown as better addition or synergistic effect, for example: the weight ratio of the active ingredients of the pyridaben to the pyridalyl is as follows: 8:1, 4:1, 8:3, 2:1, 8:5, 4:3, 8:7, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, etc. As a more preferable example, the weight ratio of the active ingredients of the pyridaben to the pyridalyl is 6:1-1:6, wherein the best effect is realized when the weight ratio of the active ingredients of the pyridaben to the pyridalyl is 1:1 or 1:2 or 1: 4.
In a preferred embodiment, the weight percentage of the active ingredients of the pyridaben and the pyridalyl is 1-80%, and as a more preferred embodiment, the weight percentage of the active ingredients of the pyridaben and the pyridalyl is 10-70%. The specific addition amount can be determined according to the field area to be treated and the types of the pests, for example, the mass of pyridaben and pyridalyl can account for 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, and the like, or any other value in the range. In a more preferred embodiment, the mass of the pyridaben and the pyridalyl accounts for 20-66% of the total mass of the insecticidal composition. Within this range, the drug effect can be exerted and the preparation of a dosage form having an excellent effect can be facilitated.
In a preferred embodiment, the pesticide composition further comprises a carrier, the carrier being one or more of water, a solvent or a filler. Wherein, the water is preferably deionized water; the solvent is selected from one or more of N, N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octyl pyrrolidone, ethanolamine, triethanolamine, isopropylamine, N-methyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol butyl ether, ethanolamine, ethyl acetate or acetonitrile; the filler is selected from one or more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate. It will be appreciated that the above categories are merely exemplary and not exhaustive and that other suitable carriers may be used in the preparation of the above compositions.
In a preferred embodiment, the pesticide composition further comprises an auxiliary agent, wherein the auxiliary agent comprises at least one surfactant, and the surfactant is selected from one or more of an emulsifier, a dispersing agent, a wetting agent or a penetrating agent.
Wherein the emulsifier is selected from OP series phosphate (nonylphenol polyoxyethylene ether phosphate), 600# phosphate (phenylphenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate, magnesium salt of alkyl diphenyl ether disulfonate, triethanolamine salt, Nostoc 400# (benzyldimethylphenol polyoxyethylene ether), Nostoc 700# (alkylphenol formaldehyde resin polyoxyethylene ether), Ningru 36# (phenethylphenol formaldehyde resin polyoxyethylene ether), agricultural cream 1600# (phenethyl phenol polyoxyethylene polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (nonylphenol polyoxyethylene ether), BY series (castor oil polyoxyethylene ether), agricultural cream 33# (alkylaryl polyoxyethylene polyoxypropylene ether), span series (sorbitan monostearate), Tween series (sorbitan fatty acid ester polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether).
The dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, calcium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether or glycerin fatty acid ester polyoxyethylene ether.
The wetting agent is selected from one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, saponin powder, silkworm excrement or soapberry powder.
The penetrating agent is selected from one or a mixture of more of penetrating agent JFC (fatty alcohol-polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone or organic silicon.
It is understood that the surfactants listed in the above examples are common single or compound formulations of nonionic or anionic surfactants, but the surfactants selected are not limited to those listed above, and may be other reasonable surfactants known to those skilled in the art.
In a preferred embodiment, the auxiliary agent further comprises one or more of an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent and an antifoaming agent.
Wherein the antifreezing agent is a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea; the thickener is selected from one or more of gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, xanthan gum, bentonite, silicon dioxide or magnesium aluminum silicate; the stabilizer is selected from one or more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate or triphenyl phosphate; the disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate; the defoaming agent is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds. It will be appreciated that the above list of adjuvants is merely illustrative and not exhaustive and that other surfactants capable of acting accordingly are suitable for use in the preparation of the composition.
The insecticidal composition provided by the invention can be prepared into any one dosage form suitable for agriculture through a known method, and the better dosage form is wettable powder, water dispersible granules, water suspending agent or dispersible oil suspending agent.
Another embodiment of the present invention provides an application of the pesticidal composition according to any one of the above preferred embodiments, for controlling hemipteran pests and lepidopteran pests in fields, wherein the hemipteran pests include trialeurodes vaporariorum and leafhopper, and the lepidopteran pests include spodoptera exigua and diamondback moth.
In a preferred embodiment, the pesticide composition further comprises a pesticide composition for controlling field aphids.
In order to more clearly and specifically describe the pesticidal composition and its application provided by the embodiments of the present invention, the following description will be given with reference to specific embodiments.
Example 1: 42% pyridaben-pyridalyl wettable powder (20:1)
Proportioning: 40% of pyridaben; 2% of pyridalyl; wetting agent sodium dodecyl sulfate 2%; 8% of dispersant calcium lignosulfonate; 18% of filler white carbon black and the balance of filler kaolin.
Example 2: 60% pyridaben-pyridalyl-pyridalyl wettable powder (9:1)
Proportioning: 54 percent of pyridaben; 6% of pyridalyl; wetting agent sodium dodecyl sulfate 2%; 8% of dispersant calcium lignosulfonate; 18% of filler white carbon black and the balance of filler kaolin.
Example 3: 45% pyridaben-pyridalyl-pyridalyl wettable powder (8:1)
Proportioning: 40% of pyridaben; 5% of pyridalyl; wetting agent sodium dodecyl sulfate 2%; 8% of dispersant calcium lignosulfonate; 18% of filler white carbon black and the balance of filler kaolin;
the preparation method of examples 1-3 was: according to the proportion, the active ingredients of pyridaben and pyridalyl are added into a carrier, and a surfactant and other functional additives are added into the carrier, mixed, subjected to air flow crushing and then mixed to prepare the wettable powder. The main equipment is mixer and jet mill.
Example 4: 28% pyridaben-pyridalyl microemulsion (6:1)
Proportioning: 24 percent of pyridaben; 4% of pyridalyl; the solvent is cyclohexanone and N, N-dimethylformamide, and the dosage is 15% and 15% respectively; the emulsifier is selected from agricultural milk 602# and agricultural milk 500# with the dosage of 9% and 6% respectively; the balance of water.
Example 5: 25% pyridaben-pyridalyl microemulsion (4:1)
Proportioning: 20% of pyridaben; 5% of pyridalyl; the solvent is cyclohexanone and N, N-dimethylformamide, and the dosage is respectively 10% and 10%; the emulsifier is selected from agricultural milk 602# and agricultural milk 500# with the dosage of 9% and 6% respectively; the balance of water.
Example 6: 15% pyridaben-pyridalyl microemulsion (2:1)
Proportioning: 10% of pyridaben; 5% of pyridalyl; the solvent is cyclohexanone and N, N-dimethylformamide, and the dosage is respectively 12% and 12%; the emulsifier is selected from agricultural milk 602# and agricultural milk 500# with the dosage of 9% and 6% respectively; the balance of water;
the preparation of examples 4-6 was as follows: according to the proportion, the effective components of pyridaben and pyridalyl are completely dissolved by using a solvent and a cosolvent, then other auxiliary agents are added and uniformly mixed, finally water is added, and the mixture is fully stirred to obtain the microemulsion preparation of the insecticidal composition.
Example 7: 30% pyridaben-pyridalyl-pyridalyl water dispersible granule (1:1)
Proportioning: 15% of pyridaben; 15% of pyridalyl; sodium dodecylbenzenesulfonate wetting agent 3%; 6% of dispersant alkyl naphthalene sulfonate formaldehyde condensate; the balance of filler attapulgite.
Example 8: 30% pyridaben-pyridalyl-pyridalyl water dispersible granule (1:2)
Proportioning: 10% of pyridaben; 20% of pyridalyl; 4% of sodium dodecyl benzene sulfonate serving as a wetting agent; 8% of dispersant alkyl naphthalene sulfonate formaldehyde condensate; the balance of filler attapulgite;
the preparation method of examples 7-8 was: adding the active ingredients pyridaben and pyridalyl into a carrier according to the proportion, adding a surfactant and other functional auxiliaries, mixing, carrying out air flow crushing, adding 10-25% of water, kneading, granulating, drying and screening to obtain a water dispersible granule product; or spraying water to the pulverized powder in a boiling granulator, granulating, drying, and sieving to obtain the final product. The main equipment comprises a mixer, a jet mill, a kneader, an extrusion granulator, a drying room or a fluidized bed for drying, or a boiling granulator and a sieving machine.
Example 9: 25% pyridaben-pyridalyl-pyridalyl aqueous suspension (1:4)
Proportioning: 5% of pyridaben; 20% of pyridalyl; emulsifier Nongru NP-10, 2%; 8% of dispersant polycarboxylate; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.15% and 1.5% respectively; 5% of antifreeze glycol; 0.2 percent of defoaming agent silicone compound; the balance of water.
Example 10: 28% pyridaben-pyridalyl pyriproxyfen aqueous suspension (1:6)
Proportioning: 4% of pyridaben; 24% of pyridalyl; emulsifier Nongru NP-10, 2%; 8% of dispersant polycarboxylate; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.12% and 1.2% respectively; 5% of antifreeze glycol; 0.2 percent of defoaming agent silicone compound; the balance of water;
the preparation method of examples 9-10 was: according to the proportion, the active ingredients of pyridaben, pyridalyl, surfactant and other functional additives are sequentially placed in a reaction kettle, water is added for uniform mixing, and the product is obtained through high-speed shearing, wet sanding and finally homogeneous filtration. The main equipment is a batching kettle, a colloid mill or a homogenizing mixer, and a sand mill.
Example 11: 32% pyridaben-pyridalyl emulsion in water (1:7)
Proportioning: 4% of pyridaben; 28% of pyridalyl; emulsifier Nongru NP-10, 2%; 2% of castor oil polyoxyethylene ether; 2% of phenyl phenol polyoxyethylene ether phosphate; 20% of a solvent; 10% of cosolvent; 5% of antifreeze glycol; 0.2 percent of defoaming agent silicone compound; the balance of water.
Example 12: 20% pyridaben-pyridalyl emulsion in water (1:9)
Proportioning: 2% of pyridaben; 18% of pyridalyl; emulsifier Nongru NP-10, 2%; 1.6 percent of castor oil polyoxyethylene ether; 2% of phenyl phenol polyoxyethylene ether phosphate; 15% of a solvent; 8% of cosolvent; 5% of antifreeze glycol; 0.2 percent of defoaming agent silicone compound; the balance of water.
Example 13: 31% pyridaben-pyridalyl emulsion in water (1:30)
Proportioning: 1% of pyridaben; 30% of pyridalyl; emulsifier Nongru NP-10, 2%; 1.6 percent of castor oil polyoxyethylene ether; 2% of phenyl phenol polyoxyethylene ether phosphate; 15% of a solvent; 8% of cosolvent; 5% of antifreeze glycol; 0.2 percent of defoaming agent silicone compound; the balance of water;
the preparation of examples 11-13 was as follows: according to the proportion, the effective components, the emulsifier, the solvent and the cosolvent are dissolved into an oil phase, and water, the antifreeze agent, the preservative, the thickening agent and other components are uniformly mixed to form a water phase; and (3) dropwise adding the oil phase into the water phase while shearing at a high speed in the reaction kettle, and shearing for a period of time to form the stable oil-in-water emulsion in water.
Indoor combined virulence bioassay
An indoor combined toxicity bioassay test is adopted to verify whether the pyridaben and the pyridalyl have synergistic effect after being compounded or not.
Test agent:
95% of pyridaben technical, 95% of pyridalyl technical;
test targets:
the test insects are first-generation adults which are bred, bred and hatched indoors from greenhouse trialeurodes vaporariorum collected from fields;
experimental procedure:
(1) preparing a medicament:
dissolving the raw medicines with acetone, respectively dissolving the two raw medicines on the basis of pre-test, diluting with 0.1% Tween 80 aqueous solution to obtain 5 medicinal solutions with gradient concentration, and placing in a beaker for use;
(2) medicament treatment:
a glass slide dipping method (refer to NY/T1154.12-2008 pesticide laboratory bioassay test standard insecticide, part 12: tetranychus urticae glass dipping method) is adopted, and the specific operation method is as follows:
5 different concentration gradients are set for each single agent and mixed agent (on the basis of a preliminary test result, the mortality of the trialeurodes vaporariorum is set in a range of 5-90% according to an geometric progression);
selecting the trialeurodes vaporariorum which is fed indoors and has consistent physiological form;
cutting the double-sided adhesive tape into 2cm long, sticking it on one end of the glass slide, selecting healthy trialeurodes vaporariorum, sticking its back on the double-sided adhesive (taking care not to stick feet, tentacles and mouthparts), placing 30 pieces each in a container with wet sponge pad, covering with a cover, and standing at (25 + -1) ° C. Performing microscopic examination after 2h, removing dead and injured individuals, and supplementing 30 heads;
soaking the glass slide in the liquid medicine, slightly oscillating for 5s, taking out, sucking off excessive liquid medicine with absorbent paper, placing in a white porcelain dish filled with wet sponge, and covering with plastic film with good light transmittance;
repeating the treatment for 4 times, and setting the treatment without medicament as blank control;
(3) feeding and observing:
feeding and observing the container containing the treated test insects under the conditions of temperature (25 +/-1 ℃) and illumination period L: D ═ (16: 8);
(4) the test environmental conditions can be properly adjusted by checking special conditions:
and (5) checking the death condition of the test insects 48 hours after treatment, and respectively recording the total number of the insects and the number of the dead insects. According to the test requirements and the medicament characteristics, the inspection time can be shortened or prolonged;
(5) data statistics and analysis:
the corrected mortality for each treatment was calculated from the survey statistics and the co-toxicity coefficient (CTC value) of the combination was calculated by the Sun cloud Peter method with reference to NY/T1154.7-2006. If the control mortality rate is less than 5%, not correcting, and the control mortality rate is between 5% and 20%, correcting, the control mortality rate is greater than 20%, and the test needs to be redone, wherein the mortality rate calculation formula is as follows:
in the formula: p-mortality in percent (%); k represents the number of dead insects and the unit is head; n- - -represents the total number of heads processed.
Respectively establishing virulence regression equations by taking the logarithm value of the medicament concentration (mg/L) as an independent variable x and the value of the corrected mortality as a dependent variable y, calculating LC50 of single dose and mixed dose by adopting DPS software, and calculating the cotoxicity coefficient (CTC) according to the Sun Yunpei method. The co-toxicity coefficient CTC is calculated according to the following formula: (pyridaben is taken as a standard medicament, and the virulence index is 100):
the theoretical virulence index (TTI) of a compounded formulation ═ Σ (virulence index ATI of a particular active ingredient x the percentage of that active ingredient in the compound);
note: the CTC is synergistic when the CTC is more than 120, antagonistic when the CTC is less than 80, and additive when the CTC is 80-120.
According to the method, the toxicity test results of the active ingredients pyridaben and pyridalyl (namely, the examples 1 to 13) on tomato whitefly are tested, and the results are shown in the following table:
TABLE 1 virulence determination results of tomato whitefly with different active ingredient ratios
As can be seen from the above table, when the active ingredients of pyridaben and pyridalyl in the pesticide composition are in a ratio of 8:1-1:6, the co-toxicity coefficients are both greater than 120, and the pesticide composition shows a synergistic effect on trialeurodes vaporariorum, particularly when the active ingredients of pyridaben: when the mass ratio of the pyridalyl is 1:1, the synergistic effect is most obvious, and the co-toxicity coefficient is 165.
Test of field drug effect
By adopting a field pesticide effect test method, the combination of pyridaben and pyridalyl in the field is further proved to have synergistic effect on pest control, and the field pesticide effect control on tomato whitefly is carried out by using the pyridaben missible oil and the pyridalyl missible oil of the above examples 4-10 and 20 percent and the pyridalyl missible oil of 10 percent.
Test methods:
the field efficacy test is designed to carry out 10 treatments of medicament, contrast medicament, clear water and the like, and the area of each test cell is 50m2And 4 times of treatment, cells are randomly arranged, and 0.5m protection rows are arranged between every two cells and around the test field. Using an artificial spraying method to apply the pesticide to the citrus, wherein 1 survey is carried out 1 time before the pesticide application, and 3 days, 7 days and 15 days after the pesticide application, wherein each survey is carried out 1 time and 4 times;
the investigation method comprises the following steps: a five-point sampling method and a listing marking method are adopted. Surveying 10 tomatoes at a fixed point in each cell, selecting different parts for each tomato to hang and mark 10 leaves, surveying the population base number and the residual population, and calculating the population decline number and the prevention and treatment effect, wherein the calculation formula is as follows:
oral cavity decline rate (%) [ (number of insects before application-number of insects after application)/number of insects before application ] × 100
Control effect (%) [ (treatment area population reduction rate-blank control area population reduction rate)/(1-blank control area population reduction rate) ] × 100
Corrected control effect (%) [ (control effect in treatment area-control area)/(control effect in 100-control area) ] × 100
Test results:
the results of the field efficacy test are shown in the following table:
TABLE 2 field efficacy test results of treatment agents for controlling tomato whitefly
It can be seen from the above data that after different formulations are compounded, and after the agents are applied for 3d, 7d and 15d, the control effect of the agents used in examples 4-10 on tomato whitefly is obviously higher than that of the control agent 1 (20% pyridaben EC) and the control agent 2 (10% pyridaben EC), the knockdown time is obviously shortened, and the quick action is good. After 15 days of pesticide application, the control effect of the pesticide on the tomato whitefly is still over 80 percent, which shows that the two effective components of pyridaben and pyridalyl are compounded according to a certain proportion to have obvious synergistic effect, the quick-acting performance is obviously better than that of a single pesticide, the lasting period is longer, and the pesticide has obvious effect on the whitefly and leafhopper. Experiments show that the compound composition obviously reduces the using amount of the medicament, and reduces the production cost, the pesticide residue and the environmental pollution.
In addition, the indoor activity determination and the field efficacy test show that the treatment liquid medicine of the embodiment medicament has no influence on the growth of crops, is safe to the surrounding beneficial organisms and has good compatibility with the environment. The pyridaben and pyridalyl compound insecticidal composition has the advantages of small dosage, capability of delaying the generation of drug resistance of pests, safety, environmental protection, short knockdown time, quick response and the like, so that the pyridaben and the pyridalyl compound insecticidal composition are ideal compound insecticidal products. The research, development and popularization of the invention have important significance for farmers to become rich and for the protection of local ecological environment.
Claims (10)
1. The insecticidal composition is characterized by comprising effective components and auxiliary components, wherein the effective components comprise pyridaben and pyridalyl, and the weight ratio of the pyridaben to the pyridalyl is 40:1-1: 40.
2. The insecticidal composition according to claim 1, wherein the weight ratio of the active ingredients pyridaben and pyridalyl is 8:1-1: 6.
3. The insecticidal composition according to claim 1, wherein the weight ratio of the active ingredients pyridaben and pyridalyl is 6:1-1: 6.
4. The insecticidal composition according to claim 1, wherein the weight ratio of the active ingredients pyridaben and pyridalyl is 1:1 or 1:2 or 1: 4.
5. The insecticidal composition according to any one of claims 1 to 4, wherein the weight percentage content of the active ingredients pyridaben and pyridalyl is 1 to 80%.
6. An insecticidal composition according to claim 5 wherein said auxiliary ingredients comprise a carrier and an adjuvant, the carrier being one or more of water, a solvent or a filler, the adjuvant comprising at least one surfactant.
7. The insecticidal composition according to claim 6, wherein the surfactant is selected from one or more of an emulsifier, a dispersant, a wetting agent or a penetrant; the auxiliary agent also comprises one or more of an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent and a defoaming agent.
8. The insecticidal composition as claimed in claim 5, wherein the formulation of the insecticidal composition is one of wettable powder, water dispersible granule, water suspension or dispersible oil suspension.
9. Use of a pesticidal composition according to any one of claims 1 to 8 for the control of hemipteran pests and lepidopteran pests in fields, said hemipteran pests including whitefly and leafhopper, and lepidopteran pests including beet armyworm and diamondback moth.
10. The use according to claim 9, further comprising control of field aphids.
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| CN114041466A (en) * | 2021-12-09 | 2022-02-15 | 中国农业科学院棉花研究所 | Insecticidal composition and preparation method and application thereof |
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| CN101669490A (en) * | 2009-09-08 | 2010-03-17 | 深圳诺普信农化股份有限公司 | Pesticide combination |
| CN102972413A (en) * | 2012-12-06 | 2013-03-20 | 海利尔药业集团股份有限公司 | Pyridalyl and flutenzine-containing insecticidal compound |
| CN110402947A (en) * | 2018-04-27 | 2019-11-05 | 吕连友 | A kind of Hexythiazox and pyridalyl mixed insecticide preparation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1088061C (en) * | 1994-10-14 | 2002-07-24 | 住友化学工业株式会社 | Dihalopropene compounds, insecticidal/acaricidal agent contg. same, and intermediates |
| CN101669490A (en) * | 2009-09-08 | 2010-03-17 | 深圳诺普信农化股份有限公司 | Pesticide combination |
| CN102972413A (en) * | 2012-12-06 | 2013-03-20 | 海利尔药业集团股份有限公司 | Pyridalyl and flutenzine-containing insecticidal compound |
| CN110402947A (en) * | 2018-04-27 | 2019-11-05 | 吕连友 | A kind of Hexythiazox and pyridalyl mixed insecticide preparation |
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| CN114041466A (en) * | 2021-12-09 | 2022-02-15 | 中国农业科学院棉花研究所 | Insecticidal composition and preparation method and application thereof |
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