CN111374137A - Insecticidal composition containing tebuconazole and chlorfenapyr - Google Patents
Insecticidal composition containing tebuconazole and chlorfenapyr Download PDFInfo
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- CN111374137A CN111374137A CN202010258210.6A CN202010258210A CN111374137A CN 111374137 A CN111374137 A CN 111374137A CN 202010258210 A CN202010258210 A CN 202010258210A CN 111374137 A CN111374137 A CN 111374137A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
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Abstract
The invention belongs to the field of pesticide, and relates to a composition containing tebuconazole and chlorfenapyr and application thereof. The pesticide composition comprises tebuconazole and chlorfenapyr, and the weight part ratio of the two active components is 1: 80-80: 1. The pesticide composition has the advantages of synergism, resistance reduction and the like, and can be used for preventing and controlling agricultural and forestry pests and sanitary pests.
Description
Technical Field
The invention belongs to the technical field of pesticides, and relates to application of a composition containing tebuconazole and chlorfenapyr to crop pests.
Background
Tetrazolamides are anthranylaminobenzamide insecticides developed by bayer (development code: BCS-CL73507), CAS accession No.: 1229654-66-3. The tebuconazole amide also belongs to bisamide insecticides, is a ryanodine receptor agent, and can efficiently activate insect ryanodine (muscle) receptors. Excessive release of calcium ions in calcium reservoirs in cells causes weakening of muscle regulation function of pests, leads to paralysis and death of insects, can be used for field crops and fruit and vegetable crops, and has wide insecticidal spectrum and good persistence.
Chlorfenapyr (Chlorfenapyr) is a novel pyrrole compound, and is a high-efficiency insecticidal and acaricidal agent developed by cyanamide company in 20 th century and 80 years later. The action mechanism is that after the insects eat or contact the chlorfenapyr, the insect is oxidized and metabolized in the insect body to be changed into a compound with insecticidal activity, then the compound acts on mitochondria of cells in the insect body, the multifunctional oxidase in the insect body acts to mainly inhibit the conversion of Adenosine Diphosphate (ADP) to Adenosine Triphosphate (ATP), and the adenosine triphosphate stores energy required by the cells to maintain the life functions of the cells, and finally the pests die.
One plant may be harmed by several kinds of pests, and most of the single agents can only control one kind of pest or one kind of pest. The effect of treating different pests can be achieved by the mixed use of two or more medicaments with different action mechanisms; can also improve the control effect and quick-acting property of the medicament, and achieve the effects of increasing the medicament effect and reducing the medicament resistance; can also improve the efficiency and reduce the medication cost. In addition, in the prior art, the technical scheme of the composition containing the tebuconazole and the chlorfenapyr is not specifically disclosed.
Disclosure of Invention
The invention aims to provide a composition containing tebuconazole and chlorfenapyr, which has a synergistic effect, low use cost and good control effect.
In order to achieve the purpose, the invention adopts the technical scheme that: an insecticidal composition containing tebuconazole and chlorfenapyr comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is tebuconazole (Tetraniliprole), and the structural formula is as follows:
the active component B is chlorfenapyr.
Further, the weight part ratio of the active ingredient A to the active ingredient B is 1: 80-80: 1;
further, the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 20-10: 1;
further, the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 5-3: 1;
further, the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 3-1: 1.
Further, the sum of the contents of the active ingredient A and the active ingredient B in the insecticidal composition is 0.5-95%, preferably 1-85% based on 100 wt% of the total mass of the insecticidal composition.
Further, the insecticidal composition also comprises an auxiliary agent, wherein the auxiliary agent comprises a carrier and an auxiliary agent;
further, the carrier is one, two or three of water, solvent or filler, and the water is preferably deionized water;
further, the solvent is selected from the group consisting of N, N-dimethylformamide, cyclohexanone, toluene, xylene, dimethyl sulfoxide, methanol, ethanol, trimethylcyclohexanone, N-octylpyrrolidone, ethanolamine, triethanolamine, and isopropylamine. One or more of N-methyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, ethanolamine, isopropylamine, ethyl acetate or acetonitrile;
further, the filler is selected from one or a mixture of more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate;
the auxiliary agent at least comprises a surfactant, and other functional auxiliary agents such as an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent, a defoaming agent, a slow release agent, a binder and the like can be added according to different use occasions and requirements;
the surfactant is selected from one or more of an emulsifier, a dispersant, a wetting agent, a dispersion medium or a penetrant.
The surfactant is a single agent or a compound preparation of a common nonionic surfactant or an anionic surfactant;
the other functional auxiliary agents are selected from one or more of an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent or a defoaming agent;
further, the emulsifier is selected from one or more of agricultural milk 500# (calcium alkyl benzene sulfonate), OP series phosphate (surfactant phosphate), 600# phosphate (phenyl phenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether wetting agent salt, magnesium salt of alkyl diphenyl ether disulfonate, triethanolamine salt, agricultural milk 400# (benzyl dimethyl phenol polyoxyethylene ether), agricultural milk 700# (alkylphenol formaldehyde resin polyoxyethylene ether), Ning milk 36# (phenethylphenol formaldehyde resin polyoxyethylene ether), agricultural milk 1600# (phenethylphenol polyoxyethylene polypropylene ether), ethylene oxide-propylene oxide block copolymer, OP series (surfactant), BY series (castor oil polyoxyethylene ether), agricultural milk 33# (alkylaryl polyoxyethylene propylene ether), span series (sorbitan monostearate), Tween series (sorbitan fatty acid ester polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether) An agent;
further, the dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene formaldehyde condensate sulfate, calcium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene, fatty amine polyoxyethylene, fatty acid polyoxyethylene or glycerol fatty acid ester polyoxyethylene;
further, the wetting agent is selected from one or a mixture of more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, Chinese honeylocust fruit powder, silkworm excrement or soapberry powder;
further, the penetrating agent is selected from a mixture consisting of one or more of penetrating agent JFC (fatty alcohol-polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone or organic silicon;
further, a dispersion medium such as one or more of soybean oil, rapeseed oil, wheat oil, methyl oleate, diesel oil, machine oil, mineral oil, and the like;
further, the antifreezing agent is a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea;
further, the thickening agent is selected from one or more of xanthan gum, a disintegrating agent, bentonite, carboxymethyl cellulose or magnesium aluminum silicate;
further, the stabilizer is selected from one or more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate and triphenyl phosphate;
further, the disintegrating agent is selected from one or more of bentonite, urea, wetting agent, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate;
further, the defoaming agent is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds.
The insecticidal composition of the invention can be prepared into the dosage forms acceptable in pesticide according to the method known by the technical personnel in the technical field, including solid preparation, liquid preparation, seed treatment agent and other preparations;
further, the solid preparation is powder, dispersible tablets, granules, soluble powder, soluble granules, soluble tablets, milk powder, milk granules, water dispersible granules, wettable powder, micro-capsule granules, macro-granules and water dispersible tablets;
further, the liquid preparation is microcapsule suspending agent, dispersible agent, missible oil, emulsion granules, oil emulsion, emulsion powder, aqueous emulsion, microemulsion, dispersible oil suspending agent, oil dispersion powder, suspending agent, suspoemulsion, soluble agent and ultra-low volume liquid;
further, the seed treatment preparation is a suspended seed coating agent, a seed treatment dry powder agent, a seed treatment dispersible powder agent, a seed treatment suspending agent and a seed treatment liquid agent;
further, the other preparation is bait, concentrated bait, gas preparation, aerosol, smoke agent;
furthermore, the preparation formulation is preferably a suspending agent, a water dispersible granule, an emulsion in water, a granule, a wettable powder and a dispersible oil suspending agent;
further, the composition is prepared into a suspending agent, and the components and the content of the suspending agent are preferably as follows: 0.1-80% of tebuconazole amide, 0.1-80% of chlorfenapyr, 2-10% of dispersing agent, 2-10% of wetting agent, 0.01-2% of defoaming agent, 0-2% of thickening agent, 0-8% of antifreezing agent and the balance of deionized water;
further, the composition is prepared into water dispersible granules, and the components and the content of the water dispersible granules are preferably as follows: 0.1-80% of tebuconazole, 0.1-80% of chlorfenapyr, 3-12% of dispersing agent, 1-8% of wetting agent, 1-10% of disintegrating agent and the balance of filler;
further, the composition is prepared into an aqueous emulsion, and the components and the content of the composition are preferably as follows: 0.1-80% of tebuconazole amide, 0.1-80% of chlorfenapyr, 5-15% of emulsifier, 2-10% of solvent, 5-10% of antifreeze, 0.5-3% of stabilizer and the balance of deionized water;
further, the composition is prepared into wettable powder, and the components and the content of the wettable powder are preferably as follows: 0.1-80% of tebuconazole amide, 0.1-80% of chlorfenapyr, 5-20% of wetting agent, 10-20% of dispersing agent and solid carrier, wherein the solid carrier is complemented to 100%;
further, the composition is prepared into granules, and the components and the content of the granules are preferably as follows: 0.1-80% of tebuconazole amide, 0.1-80% of chlorfenapyr, 2-10% of dispersing agent, 2-10% of wetting agent and the balance of filler;
further, the composition is prepared into the dispersible oil suspending agent, and the components and the content of the dispersible oil suspending agent are preferably as follows: 0.1-80% of tebuconazole amide, 0.1-80% of chlorfenapyr, 1-15% of dispersing agent, 0.5-20% of emulsifying agent, 1-10% of wetting agent, 1-10% of thickening agent, 0-10% of antifreezing agent and the balance of dispersing medium.
Further, the application of the insecticidal composition in the aspect of preventing and controlling agricultural and forestry pests and sanitary pests;
still further, the agricultural and forestry pests and sanitary pests are lepidoptera, coleopteran and dipteran pests; further, the lepidoptera pests are diamondback moths, beet armyworms and cabbage caterpillars; the coleoptera pests are phyllotreta striolata and potato flea beetles; the dipteran pest is bradysia odoriphaga and leaf miner.
Further, the agricultural and forestry pests and the sanitary pests are lepidoptera pests on cruciferous plants;
still further, the lepidopteran pest on the cruciferous plants is asparagus caterpillar.
Further, the pesticidal composition is applied to a pest or a medium in which it grows in need of control in an effective amount.
The insecticidal composition of the invention has the following advantages: the composition shows synergistic effect in a certain proportion range, and improves the control effect of the composition on pests; the control targets of all effective components in the composition are different, so that the insecticidal range can be enlarged, and the production cost can be effectively reduced; the two active components in the composition have different action mechanisms, so that the generation of drug resistance of pests is effectively delayed, and the service life of the product is prolonged; the two active components in the composition are combined in a proper proportion range, so that the pest control effect is improved.
Detailed Description
The invention will be further illustrated by reference to the following examples, which are not intended to limit the invention thereto, but are in each case based on the weight.
The compositions of the present invention may be provided in the form of a finished formulation. Can be prepared into suspending agents, water dispersible granules, emulsion in water, granules, wettable powder, dispersible oil suspending agents and the like according to requirements. The sum of the contents of the insecticidal composition is 0.5-95%, preferably 1-85%. The amount of active ingredient present in the compositions of the invention depends on the application rate used alone, on the compounding ratio and on the degree of synergism. The optimum range of active ingredient content will vary depending upon the type of formulation of the composition.
Formulation preparation example:
example 1: 30% Tebuconazole-chlorfenapyr suspending agent (1:2)
The formula is as follows: 10% of tebuconazole amide, 20% of chlorfenapyr, 2% of alkyl sodium sulfate, 3% of alkylphenol formaldehyde resin polyoxyethylene ether, 0.4% of carboxymethyl cellulose, 5% of propylene glycol, 0.2% of isothiazolinone and deionized water, wherein the balance is made up;
the preparation method comprises the following steps: according to the formula proportion, the effective components of the tebuconazole amide, the chlorfenapyr, the surfactant and other functional auxiliaries are sequentially placed in a reaction kettle, water is added for uniform mixing, and the suspending agent product is obtained through high-speed shearing, wet sanding and finally homogeneous filtration.
Example 2: 20% Tebuconazole-chlorfenapyr suspending agent (1:1)
The formula is as follows: 10% of tebuconazole amide, 10% of chlorfenapyr, 10% of dodecyl polyoxyethylene ether phosphate, 2% of sodium alkyl polyoxyethylene ether sulfonate, 0.4% of magnesium aluminum silicate, 0.2% of carboxyethyl cellulose, 4% of sorbitol, 0.1% of sodium benzoate, 0.5% of silicone oil and deionized water for balancing;
the preparation method comprises the following steps: the same as in example 1.
Example 3: 30% Tebuconazole-chlorfenapyr suspending agent (1:1)
The formula is as follows: 15% of tebuconazole amide, 15% of chlorfenapyr, 8% of dodecyl polyoxyethylene ether phosphate, 2% of alkyl polyoxyethylene ether sodium sulfonate, 0.4% of xanthan gum, 0.1% of carboxyethyl cellulose, 3% of sorbitol, 0.1% of sodium benzoate, 0.5% of silicone oil and deionized water, and the balance is made up;
the preparation method comprises the following steps: the same as in example 1.
Example 4: 30% tebuconazole-chlorfenapyr water dispersible granule (1:1)
The formula is as follows: 15% of tebuconazole amide, 15% of chlorfenapyr, 4% of lignosulfonate, 3% of sodium dodecyl benzene sulfonate, 5% of aluminum chloride and the balance of white carbon black.
The preparation method comprises the following steps: adding active ingredients of tebuconazole and chlorfenapyr into a carrier according to the formula proportion of an embodiment, adding a surfactant and other functional auxiliaries, mixing, performing jet milling, adding 10-25% of water, kneading, granulating, drying and screening to obtain a water dispersible granule product; or spraying water to the pulverized powder in a boiling granulator, granulating, drying, and sieving to obtain the final product.
Example 5: 30% tebuconazole-chlorfenapyr water dispersible granule (1:2)
The formula is as follows: 10% of tebuconazole amide, 20% of chlorfenapyr, 5% of lignosulfonate, 3% of nekal BX, 5% of aluminum chloride and kaolin for supplementing the balance.
The preparation method comprises the following steps: the same as in example 4.
Example 6: 20% Tebuconazole amide-chlorfenapyr water dispersible granule (1:3)
The formula is as follows: 5% of tebuconazole amide, 15% of chlorfenapyr, 5% of sodium salt of a naphthalene sulfonic acid formaldehyde condensate, 4% of nekal BX, 8% of aluminum chloride and kaolin for supplementing the balance.
The preparation method comprises the following steps: the same as in example 4.
Example 7: 25% Tebuconazole-chlorfenapyr emulsion in water (2:3)
The formula is as follows: 10% of tebuconazole amide, 15% of chlorfenapyr, 12% of phosphate, 8% of propylene glycol and deionized water;
the preparation method comprises the following steps: according to the formula proportion of the embodiment, the active ingredient tebuconazole amide, the chlorfenapyr, the solvent and the emulsifier are added together to be dissolved into a uniform oil phase; mixing deionized water and an antifreezing agent together to form a uniform water phase; adding the oil phase into the water phase while stirring at a high speed in the reaction kettle, slowly adding water until a phase inversion point is reached, starting a shearing machine to shear at a high speed, adding the rest water, and shearing for about half an hour to form the aqueous emulsion.
Example 8: 20% Tebuconazole-chlorfenapyr emulsion in water (1:3)
The formula is as follows: 5% of tebuconazole amide, 15% of chlorfenapyr, 3% of farm milk 1601#, 7% of ethylene glycol and deionized water to make up the balance;
the preparation method comprises the following steps: the same as in example 7.
Example 9: 30% Tebuconazole-chlorfenapyr emulsion in water (1:2)
The formula is as follows: 10% of tebuconazole amide, 20% of chlorfenapyr, 6% of phosphate, 7% of ethylene glycol and deionized water to make up the balance;
the preparation method comprises the following steps: the same as in example 7.
Example 10: 0.9% Tebuconazole amide-chlorfenapyr granules (1:2)
The formula is as follows: 0.3 percent of tebuconazole amide, 0.6 percent of chlorfenapyr, 4 percent of nekal BX, 3 percent of wetting penetrant F, 13 percent of lignosulfonate and light calcium carbonate for supplementing the balance;
the preparation method comprises the following steps: weighing the active ingredients of the tebuconazole amide, the chlorfenapyr, the binder and the carrier according to a required proportion, crushing the tebuconazole amide and the chlorfenapyr, mixing the crushed tebuconazole amide and the ground chlorfenapyr with the carrier, adding the binder, stirring and granulating, and packaging after the inspection is qualified to obtain the product.
Example 11: 1% Tebuconazole amide-chlorfenapyr granules (1:1)
The formula is as follows: 0.5 percent of tebuconazole amide, 0.5 percent of chlorfenapyr, 10 percent of nekal BX, 12 percent of wetting penetrant F, 2 percent of polycarboxylate and bentonite for supplementing the balance;
the preparation method comprises the following steps: the same as in example 10.
Example 12: 3% Tebuconazole amide-chlorfenapyr granules (1:1)
The formula is as follows: 1.5 percent of tebuconazole amide, 1.5 percent of chlorfenapyr, 13 percent of sodium dodecyl benzene sulfonate, 1 percent of Chinese honeylocust fruit powder, 13 percent of lignosulfonate and bentonite for residue supplement;
the preparation method comprises the following steps: the same as in example 10.
Example 13: 30% tebuconazole-chlorfenapyr wettable powder (1:2)
The formula is as follows: 10% of tebuconazole amide, 20% of chlorfenapyr, 7% of polycarboxylate, 4% of sodium dodecyl benzene sulfonate and kaolin for supplementing;
the preparation method comprises the following steps: according to the formula proportion of the embodiment, the effective components of the tebuconazole and the chlorfenapyr are added into the carrier, and the surfactant and other functional additives are added into the carrier, mixed, subjected to air flow crushing and then mixed to prepare the wettable powder.
Example 14: 24% tebuconazole-chlorfenapyr wettable powder (3:5)
The formula is as follows: 9% of tebuconazole amide, 15% of chlorfenapyr, 1% of fatty amine polyoxyethylene ether, 3% of sodium dodecyl benzene sulfonate and kaolin for supplementing the balance;
the preparation method comprises the following steps: the same as in example 13.
Example 15: 24% tebuconazole-chlorfenapyr wettable powder (1:3)
The formula is as follows: 6 percent of tebuconazole amide, 18 percent of chlorfenapyr, 5 percent of alkylphenol ethoxylates, 3 percent of wetting penetrant F and diatomite for balance;
the preparation method comprises the following steps: the same as in example 13.
Example 16: 20% tetrazolium amide chlorfenapyr dispersible oil suspending agent (1:3)
The formula is as follows: 5% of tebuconazole amide, 15% of chlorfenapyr, 2% of Nongru No. 700, 5% of Nongru S-80, 10% of methyl oleate, 3% of white carbon black, 1 part of Nongru T-20 and the balance of soybean oil;
the preparation method comprises the following steps: according to the formula proportion, the active ingredient tebuconazole amide, the chlorfenapyr, the surfactant and other functional auxiliaries are sequentially placed in a reaction kettle, added with oil and uniformly mixed, subjected to high-speed shearing, wet sanding and finally homogenized and filtered to obtain the product.
Example 17: 25% tetrazolium amide chlorfenapyr dispersible oil suspending agent (2:3)
The formula is as follows: 10% of tebuconazole amide, 15% of chlorfenapyr, 1% of Nongru S-80, 2% of Nongru 700#, 5% of Nongru 0203B, 10% of methyl oleate, 3% of white carbon black, 1% of Nongru T-20 and the balance of soybean oil;
the preparation method comprises the following steps: the same as in example 16.
Example 18: 40% tetrazolium amide chlorfenapyr dispersible oil suspending agent (1:1)
The formula is as follows: 20% of tebuconazole amide, 20% of chlorfenapyr, 6% of Nongru 0201B, 2% of Nongru No. 700, 5% of Nongru S-80, 10% of methyl oleate, 3% of white carbon black, 1% of Nongru T-20 and the balance of rapeseed oil;
the preparation method comprises the following steps: the same as in example 16.
Indoor biological activity assay
Example 19: combined toxicity of tebuconazole amide and chlorfenapyr mixed on cabbage spodoptera exigua
The embodiment of the invention adopts a method combining indoor toxicity measurement and field test. Firstly, determining the co-toxicity coefficient (CTC) of two medicaments compounded according to a certain proportion by indoor toxicity measurement, wherein the CTC is less than 80 and is antagonistic, the CTC is more than 120 and is synergistic, and the CTC is added between 80 and 120, and then carrying out field test on the basis.
The test is carried out according to NY/T1154.14-2008 'indoor pesticide bioassay test standard part 14 leaf dipping method'.
The tested pests: spodoptera exigua (Hiibner,1808), a consistent 3-instar larva was housed.
Test agents: the 96% tebuconazole technical material and the 98% chlorfenapyr technical material are provided by the Hill pharmaceutical industry group Limited company.
Preparing a medicament: the original drug is dissolved by DMF respectively to prepare high-concentration mother liquor, and the mother liquor is diluted by 0.1% Tween 80 aqueous solution, and 5 different concentrations are set for each treatment for standby.
The test was repeated: 80 heads were treated at each concentration and divided into 4 replicates, with an aqueous solution containing 0.1% Tween 80 as a control.
Medicament treatment: soaking fresh leaves of caulis et folium Brassicae Capitatae in different concentrations of medicinal liquid for 10s, taking out, removing excessive medicinal liquid, air drying, and culturing in culture dish with diameter of 12 cm. Each plate was picked with 20 larvae of 3 instar spodoptera exigua, and each treatment was repeated 4 times.
Feeding and observing: and (3) feeding and observing the treated test insects under the conditions that the temperature is 25 ℃, the humidity is 60-70%, the photoperiod is L: D: 16h:8h, and checking the dead insect number on each leaf 48h after treatment.
Data statistics and analysis: the blank control mortality rate is less than 5% without correction; the blank control mortality rate is 5% -10%, and the mortality rate needs to be corrected; the blank mortality rate was above 10%, and the test was repeated. The calculation formula is as follows:
by LC50The relatively small-value agent is a standard agent, and the virulence index TI thereof is 100.
The theoretical toxicity index TTI ═ TI of mixed agentA×PA+TIB×PB
Co-toxicity coefficient
In the formula: pA、PBRespectively the proportion of the active component A, B in the composition.
Wherein A is tebuconazole and B is chlorfenapyr.
And (3) test results: see Table 1
TABLE 1 indoor toxicity test results of tebuconazole amide and chlorfenapyr compounded on cabbage beet armyworm
As can be seen from Table 1, the tebuconazole amide and chlorfenapyr are mixed to have a good combined effect on cabbage spodoptera exigua, the co-toxicity coefficient is greater than 80 when the weight ratio of the tebuconazole amide to the chlorfenapyr is 1: 80-80: 1, the co-toxicity coefficient is greater than 120 when the weight ratio of the tebuconazole amide to the chlorfenapyr is 1: 5-3: 1, the co-toxicity coefficient is greater than 140 when the weight ratio of the tebuconazole amide to the chlorfenapyr is 1: 3-1: 1, the co-toxicity coefficient is 161.74 at most when the weight ratio of the tebuconazole amide to the chlorfenapyr is 1:2, and the co-toxicity coefficient is not higher than the co-toxicity coefficient. The reasonability and feasibility of the tebuconazole and chlorfenapyr mixed control of cabbage spodoptera exigua are demonstrated.
Examples of the effects of the field
Example 20: tebuconazole amide and chlorfenapyr mixed field control effect on cabbage spodoptera exigua
Test crops and targets: cabbage, Spodoptera exigua (Hiibner, 1808).
Test site: village village of Qiao West city of Qingdao city
Test time: 6 and 15 months in 2019
And (3) test environment: the damage degree of the cabbages is consistent, the cultivation conditions of all test districts are uniform and consistent, and the same fertilizer and water management level is adopted.
Test agents: 20 percent of tebuconazole amide-chlorfenapyr suspending agent (1:1), 30 percent of tebuconazole amide-chlorfenapyr water dispersible granule (1:2), 10 percent of tebuconazole amide suspending agent and 20 percent of chlorfenapyr suspending agent, which are provided by research and development centers of Heliel pharmaceutical industry group Limited.
The test basis is as follows: GB-T17980.13-2000 part 13 of pesticide field efficacy test guidelines: the pesticide can be used for preventing and treating Lepidoptera larva of cruciferous vegetables.
The test method comprises the following steps: the application is started when the number of cabbage spodoptera exigua in each cell is not less than 20, and the application is carried out for 1 time.
Cell area and repetition: each cell was 20 square meters, repeated 4 times per treatment.
The investigation method comprises the following steps: 30 cabbages are investigated in each cell, population base number is investigated before pesticide application, and survival number of cabbage spodoptera exigua is investigated 1 day, 3 days and 7 days after pesticide application.
Calculation formula and data analysis:
the prevention and treatment effect calculation formula is as follows:
in the formula:
PT: control effect,%;
PT0the number of live insects before the pesticide is applied in the pesticide treatment area is the unit of head;
PT1the number of live insects after the pesticide is applied in the pesticide treatment area is the head;
CK0the number of live insects in unit of head before drug application in the blank control area;
CK1the number of live insects in unit of head after the drug is applied to the blank control area.
Two decimal points are reserved in the calculation result.
TABLE 2 Tebuconazole amide and Chlorfenapyr mixture for preventing and controlling cabbage beet armyworm field drug effect
Note: the data are average values of 4 repetitions, and the numerical values retain two decimal points.
The test result shows that: the 20% tebuconazole amide and chlorfenapyr suspending agent (1:1) and the 30% tebuconazole amide and chlorfenapyr water dispersible granule (1:2) have better control effect on cabbage beet armyworm, and each compound medicament with control effect at 1d, 3d and 7d after application is superior to two single agents, namely 10% tebuconazole amide suspending agent and 30% chlorfenapyr suspending agent; the control effect of the 30% tebuconazole amide and chlorfenapyr water dispersible granule (1:2) on cabbage beet armyworm is slightly better than that of the 20% tebuconazole amide and chlorfenapyr suspending agent (1:1), and the lowest dose of the 30% tebuconazole amide and chlorfenapyr water dispersible granule (1:2) is 10g ai/hm2The control effect is 61.96 percent, the control effect is 87.52 percent after 7 days, and the control effect shows better quick action and persistence.
Through indoor toxicity measurement and field tests, the pesticide composition compounded by the tetrazolium amide and the chlorfenapyr has a good control effect on lepidoptera pest spodoptera exigua. The pesticide composition or the preparation thereof obtained by compounding has obvious control effect, and is superior to a single preparation in the aspects of delaying the generation of drug resistance and prolonging the drug-holding property. And the compound pesticide is not found to cause phytotoxicity to crops in the test, which shows that the production cost and the use cost can be reduced and the pesticide composition or the preparation is safe to the crops under the condition of improving the insecticidal synergy.
Although the invention has been described in detail with respect to the general description and the specific embodiments, it will be apparent to those skilled in the art that modifications and improvements can be made thereto without departing from the spirit of the invention.
Claims (10)
1. An insecticidal composition containing tebuconazole and chlorfenapyr is characterized in that: the composition comprises an active component A and an active component B, wherein the active component A is tebuconazole (Tetraniliprole), and the structural formula is as follows:
the active component B is chlorfenapyr.
2. The insecticidal composition of claim 1, wherein: the weight part ratio of the active component A to the active component B is 1: 80-80: 1.
3. The insecticidal composition of claim 1, wherein: the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 20-10: 1.
Preferably, the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 5-3: 1;
more preferably, the mass ratio of the tebuconazole amide to the chlorfenapyr is 1: 3-1: 1.
4. An insecticidal composition according to any one of claims 1 to 3, characterized in that: the sum of the contents of the active ingredient A and the active ingredient B in the insecticidal composition is 0.5-95%, preferably 1-85% calculated by the total mass of the insecticidal composition being 100 wt%.
5. An insecticidal composition according to any one of claims 1 to 4, characterized in that: the insecticidal composition also comprises an auxiliary agent, wherein the auxiliary agent comprises a carrier and an auxiliary agent.
6. An insecticidal composition according to any one of claims 1 to 5, characterized in that: the insecticidal composition can be prepared into preparations acceptable in pesticides, including solid preparations, liquid preparations, seed treatment agents and other preparations;
preferably, the preparation is in the form of a suspending agent, a water dispersible granule, an emulsion in water, a granule, a wettable powder and a dispersible oil suspending agent.
7. The use of the pesticidal composition of any one of claims 1-6 for controlling agricultural and forestry pests, sanitary pests.
8. Use of an insecticidal composition according to claim 7, characterized in that: the agricultural and forestry pests and sanitary pests are lepidoptera, coleopteran and dipteran pests;
preferably, the lepidoptera pests are diamondback moths, beet armyworms and cabbage caterpillars; the coleoptera pests are phyllotreta striolata and potato flea beetles; the dipteran pest is bradysia odoriphaga and leaf miner.
9. Use according to any one of claims 7 to 8, characterized in that: the agricultural and forestry pests and the sanitary pests are lepidoptera pests on cruciferous plants;
preferably, the lepidopteran pest on the cruciferous plants is beet armyworm.
10. Use of a composition according to claims 7-9, characterized in that: the insecticidal composition is applied to the pests or the medium in which the pests need to be controlled in an effective dose.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068235A (en) * | 2010-06-18 | 2013-04-24 | 拜耳知识产权有限责任公司 | Active substance combinations with insecticide and acaricide properties |
| CN109258651A (en) * | 2018-10-19 | 2019-01-25 | 海利尔药业集团股份有限公司 | A kind of Pesticidal combination containing bromine worm fluorobenzene bisamide and capillary |
| CN112568224A (en) * | 2019-09-27 | 2021-03-30 | 青岛奥迪斯生物科技有限公司 | Insecticidal composition containing bromofenoxaprop-p-fluorobenzene bisamide and diafenthiuron |
-
2020
- 2020-04-03 CN CN202010258210.6A patent/CN111374137A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103068235A (en) * | 2010-06-18 | 2013-04-24 | 拜耳知识产权有限责任公司 | Active substance combinations with insecticide and acaricide properties |
| CN109258651A (en) * | 2018-10-19 | 2019-01-25 | 海利尔药业集团股份有限公司 | A kind of Pesticidal combination containing bromine worm fluorobenzene bisamide and capillary |
| CN112568224A (en) * | 2019-09-27 | 2021-03-30 | 青岛奥迪斯生物科技有限公司 | Insecticidal composition containing bromofenoxaprop-p-fluorobenzene bisamide and diafenthiuron |
Non-Patent Citations (1)
| Title |
|---|
| 刘步林: ""水乳剂定义"", 《农药剂型加工技术（第二版）》 * |
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