CN114712282A - Peony skin-care antibacterial composition and skin-care antibacterial liquid soap prepared from same - Google Patents
Peony skin-care antibacterial composition and skin-care antibacterial liquid soap prepared from same Download PDFInfo
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- CN114712282A CN114712282A CN202210364856.1A CN202210364856A CN114712282A CN 114712282 A CN114712282 A CN 114712282A CN 202210364856 A CN202210364856 A CN 202210364856A CN 114712282 A CN114712282 A CN 114712282A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention belongs to the technical field of liquid soap processing, and particularly relates to a peony skin-care antibacterial composition and a skin-care antibacterial liquid soap prepared from the same. The peony skin-care antibacterial composition disclosed by the invention achieves a high-efficiency antibacterial effect by utilizing the synergistic antibacterial effect of natural plant extracts such as a peony flower extract, a peony root extract, a rosemary extract and a mint extract, has good skin-care and antibacterial effects, and can be used for developing skin-care antibacterial care products.
Description
Technical Field
The invention belongs to the technical field of liquid soap processing, and particularly relates to a peony skin-care antibacterial composition and a skin-care antibacterial liquid soap prepared from the same.
Background
Skin, especially hand skin, is often exposed to air and is often in contact with various objects, and therefore, skin is the most vulnerable human tissue to bacteria, and many pathogens are likely to enter the mouth through the hand skin or cause body infection through contact of the hand skin with the nasal mucosa and eyes. Therefore, inhibiting or killing pathogens on the skin surface is one of the effective means to prevent infection and spread of disease.
Daily chemical articles such as soap are one of common washing articles in real life, and mainly aim at the skin of a human body, such as washing hands, faces, bathing and the like. Most of soap products sold in the market at present exist in a solid form, the solid soap is easy to lose water and crack and increase hardness in the using process and is difficult to store, the pH value of the solid soap is generally alkaline, and the weak acid environment on the surface of the skin can be damaged after long-term use, so that various uncomfortable symptoms such as roughness, crack and desquamation of the skin can be caused. With the gradual improvement of living standard, people have further knowledge on the pursuit of health, and people hope to protect the health of skin while cleaning the skin. The liquid soap has the advantages of convenient use, mildness, comfort and the like, and is gradually a favorite daily washing article.
Consumers prefer to purchase antibacterial washing products in order to inhibit or kill pathogens on the skin surface. The traditional antibacterial washing products are generally added with a certain amount of chemical antibacterial components on the basis of common washing products, and can play an antibacterial role while cleaning the skin. However, the long-term use of washing products containing chemical antibacterial agents causes certain damage to the skin, and chemical components may also cause systemic toxic and side effects by penetrating into the body through the skin or entering the body through the oral cavity. In addition, chemical biocides also cause environmental pollution. Many plants contain natural antibacterial components, and the natural extract also has the skin care effects of moisturizing, moistening the skin and the like, and is a natural, green and environment-friendly antibacterial agent. Therefore, the addition of natural antibacterial agents to liquid toilet soaps is gaining increasing consumer acceptance.
Disclosure of Invention
Therefore, the technical problem to be solved by the invention is to provide a peony skin-care antibacterial composition;
the second technical problem to be solved by the invention is to provide the skin-care antibacterial liquid soap which contains natural skin-care antibacterial ingredients and is easy to industrially produce.
In order to solve the technical problems, the peony skin-care antibacterial composition provided by the invention comprises the following raw materials in parts by weight: 3-120 parts of surfactant, 1-20 parts of humectant, 0.05-5 parts of skin conditioner, 0.2-3 parts of viscosity regulator, 2-30 parts of peony extract, 5-40 parts of peony root extract, 4-80 parts of rosemary extract, 0.01-1 part of mint extract and 30-100 parts of water.
Preferably, the peony skin-care antibacterial composition comprises the following raw materials in parts by weight: 27 parts of surfactant, 1.1 parts of humectant, 0.1 part of skin conditioner, 1 part of viscosity regulator, 5 parts of peony extract, 5 parts of peony root extract, 10 parts of rosemary extract, 0.2 part of mint extract and 50 parts of water.
Preferably, the peony extract is an ethanol extract of peony, and the specific extraction step can refer to a conventional ethanol extraction process.
Preferably, the peony root extract is an ethanol extract of peony root bark, and the specific extraction step can refer to a conventional ethanol extraction process.
Preferably, the rosemary extract is a water extract of rosemary leaves, and the specific extraction step can refer to a conventional water extraction process.
Preferably, the mint extract is a water extract of mint leaves, and the specific extraction steps can refer to a conventional ethanol extraction process.
Specifically, the peony skin-care antibacterial composition comprises the following components in parts by weight:
the surfactant comprises one or a mixture of more of coco glucoside, coconut fatty acid diethanolamide, fatty alcohol ether ester sodium sulfate, cocamidopropyl betaine, olive oil foaming agent, lauramidopropyl betaine, sodium cocoeth sulfate, PEG-7 glyceryl cocoate, sodium lauroyl amino acid and sodium cocoyl malic amino acid;
the humectant comprises one or more of glycerol, butanediol, pentanediol, hexanediol, propylene glycol, polyethylene glycol, xylitol, polypropylene glycol, sorbitol, sodium pyrrolidone carboxylate, erythritol, panthenol, hyaluronic acid, betaine, allantoin, and trehalose;
the skin conditioner comprises one or more of dipotassium glycyrrhizinate, nicotinamide, glabridin, glycyrrhetinic acid, and arbutin;
the viscosity regulator comprises one or more of sodium sulfate, sodium chloride and magnesium chloride.
The invention also discloses application of the peony skin-care antibacterial composition in preparing skin-care antibacterial liquid soap.
The invention also discloses a skin-care antibacterial liquid soap prepared based on the peony skin-care antibacterial composition.
The invention also discloses a method for preparing the skin-care antibacterial liquid soap, which comprises the steps of fully and uniformly mixing selected amounts of the surfactant, water, a skin conditioner, a humectant, a viscosity regulator, a peony flower extract, a peony root extract, a rosemary extract and a mint extract in sequence, and degassing to obtain the required skin-care antibacterial liquid soap.
Specifically, the preparation method of the skin-care antibacterial liquid soap comprises the following steps:
(1) sequentially adding a selected amount of the surfactant and deionized water into a stirring kettle, heating to 70-85 ℃, and continuously stirring for 40-50min to prepare a first mixture solution;
(2) fully stirring the first mixture solution, cooling, adding a selected amount of the skin conditioner, the humectant and the viscosity regulator when the temperature is reduced to 50-60 ℃, and continuously stirring for 40-50min to prepare a second mixture solution;
(3) and cooling the second mixture solution, respectively adding a selected amount of the peony flower extract, the peony root extract, the rosemary extract and the mint extract when the temperature is reduced to 30-45 ℃, continuously stirring for 20-30min, and degassing to obtain the required skin-care antibacterial liquid soap.
Specifically, in the step (3), the degassing treatment step is vacuum degassing treatment, preferably, the vacuum degree is controlled to be-0.02 to 0.06MPa, and the degassing time is 30 to 45 min.
Specifically, in the preparation method of the skin-care antibacterial liquid soap, the rotation speed in the stirring step is preferably controlled to be 20-35 rpm.
The peony skin-care antibacterial composition disclosed by the invention achieves a high-efficiency antibacterial effect by utilizing the synergistic antibacterial effect of natural plant extracts such as a peony flower extract, a peony root extract, a rosemary extract and a mint extract, has good skin-care and antibacterial effects, and can be used for developing skin-care antibacterial care products.
The skin-care antibacterial liquid soap is prepared based on the peony skin-care antibacterial composition, a surfactant, a humectant, a skin conditioner, a viscosity regulator, a peony flower extract, a peony root extract, a rosemary extract and a mint extract are used as effective components, a natural plant extract with good antibacterial effect is adopted to replace a chemical antibacterial agent in the traditional liquid soap, and organic acids and polyphenols in the peony flower and peony root extract can play an antibacterial role by changing the pH value in a pathogen cell membrane or changing the permeability of the pathogen cell membrane; in addition, the peony and peony root extracts also contain polysaccharide and flavonoid components, and have good effects of resisting oxidation and promoting hand blood circulation. The skin-care antibacterial liquid soap disclosed by the invention can clean skin and play a role in high-efficiency bacteriostasis, meanwhile, various natural components in the plant extract have good effects of resisting oxidation and promoting blood circulation of hands, and the liquid soap is free of skin irritation, and is safe, healthy, green and environment-friendly.
Drawings
In order that the present disclosure may be more readily and clearly understood, the following detailed description of the present disclosure is provided in connection with specific embodiments thereof and the accompanying drawings, in which,
fig. 1 shows the result of the detergency of the liquid soap, wherein a is the peony skin-care antibacterial liquid soap of example 1; b is the peony skin-care antibacterial liquid soap of the embodiment 2; c is the peony skin care antibacterial liquid soap of example 3;
fig. 2 is the result of the antibacterial performance of the liquid soap, wherein a is the peony skin-care antibacterial liquid soap of example 1; b is the peony skin-care antibacterial liquid soap of the embodiment 2; c is the peony skin care antibacterial liquid soap of example 3.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention.
Preparation example 1 peony extract
The peony extract in the preparation example is prepared according to the following method: freeze-drying fresh peony flowers, crushing, sieving with a 16-mesh sieve, placing 2g of crushed peony flowers in 80mL of extraction solvent (ethanol: water: 70: 30, v/v), performing ultrasonic treatment at the ultrasonic power of 260W for 1 hour, and performing suction filtration to obtain the required peony flower extract.
Preparation example 2 peony root extract
The peony root extract in the preparation example is prepared according to the following method: adding 5g of peony root bark powder into 50mL of 80% ethanol, carrying out reflux extraction at 80 ℃ for 4 hours, and carrying out suction filtration to obtain a peony root bark extract.
Preparation example 3 Rosemary extract
The rosemary extract described in this preparation example was prepared as follows: 20g of fresh rosemary leaves are taken, 60mL of deionized water is added for distillation, and then the extract of the labdane is obtained.
Preparation example 4 mint extract
The mint extract described in this preparation example was prepared as follows: taking 20g of fresh mint leaves, adding 100mL of deionized water, carrying out reflux extraction at 85 ℃ for 3 hours, and filtering to obtain the mint extract.
Example 1
The skin-care antibacterial liquid soap comprises the following components in parts by weight: 27 parts of coco glucoside, 1.1 parts of butanediol, 0.1 part of glycyrrhetinic acid, 1 part of sodium chloride, 5 parts of peony extract, 5 parts of peony root extract, 10 parts of rosemary extract, 0.2 part of mint extract and 50 parts of deionized water.
The preparation method of the skin-care antibacterial liquid soap comprises the following steps:
(1) sequentially adding the surfactant and deionized water into a stirring kettle, heating to 75 ℃, and continuously stirring for 45min at the rotating speed of 30rpm to prepare a first mixture solution;
(2) stirring and cooling the first mixture solution, adding a skin conditioner, a humectant and a viscosity regulator when the temperature is reduced to 55 ℃, and continuously stirring for 45min at the rotating speed of 30rpm to prepare a second mixture solution;
(3) cooling the second mixture solution, respectively adding flos moutan extract, radix moutan extract, herba Rosmarini officinalis extract and herba Menthae extract when the temperature is reduced to 35 deg.C, stirring at 30rpm for 25min, and vacuum degassing at-0.04 Mpa for 40min to obtain the final product.
Example 2
The skin-care antibacterial liquid soap comprises the following components in parts by weight: 15 parts of cocamidopropyl betaine, 5 parts of glycerol, 0.2 part of nicotinamide, 1.5 parts of magnesium chloride, 10 parts of peony flower extract, 15 parts of peony root extract, 8 parts of rosemary extract, 0.5 part of mint extract and 60 parts of deionized water.
The preparation method of the skin-care antibacterial liquid soap comprises the following steps:
(1) sequentially adding the surfactant and deionized water into a stirring kettle, heating to 70 ℃, and continuously stirring at the rotating speed of 35rpm for 40min to prepare a first mixture solution;
(2) stirring and cooling the first mixture solution, adding a skin conditioner, a humectant and a viscosity regulator when the temperature is reduced to 50 ℃, and continuously stirring at the rotating speed of 35rpm for 40min to prepare a second mixture solution;
(3) cooling the second mixture solution, respectively adding flos moutan extract, radix moutan extract, herba Rosmarini officinalis extract and herba Menthae extract when the temperature is reduced to 30 deg.C, stirring at 35rpm for 20min, and vacuum degassing at-0.02 Mpa for 45min to obtain the final product.
Example 3
The skin-care antibacterial liquid soap comprises the following components in parts by weight: 65 parts of coconut oil fatty acid diethanolamide, 10 parts of hyaluronic acid, 0.07 part of nicotinamide, 0.9 part of sodium sulfate, 20 parts of peony extract, 10 parts of peony root extract, 40 parts of rosemary extract, 0.5 part of mint extract and 45 parts of deionized water.
The preparation method of the skin-care antibacterial liquid soap comprises the following steps:
(1) sequentially adding the surfactant and deionized water into a stirring kettle, heating to 85 ℃, and continuously stirring at the rotating speed of 20rpm for 50min to prepare a first mixture solution;
(2) stirring the first mixture solution, cooling, adding skin conditioner, humectant and viscosity regulator when the temperature is reduced to 60 deg.C, and stirring at 20rpm for 50min to obtain second mixture solution;
(3) cooling the second mixture solution, respectively adding flos moutan extract, radix moutan extract, herba Rosmarini officinalis extract and herba Menthae extract when the temperature is reduced to 45 deg.C, stirring at 20rpm for 30min, and vacuum degassing at-0.06 Mpa for 30min to obtain the final product.
Example 4
The skin-care antibacterial liquid soap comprises the following components in parts by weight: 3 parts of PEG-7 glyceryl cocoate, 20 parts of panthenol, 0.05 part of arbutin, 3 parts of sodium chloride, 2 parts of peony extract, 40 parts of peony root extract, 4 parts of rosemary extract, 1 part of mint extract and 100 parts of deionized water.
The skin care antibacterial liquid soap of this example was prepared in the same manner as in example 1.
Example 5
The skin-care antibacterial liquid soap comprises the following components in parts by weight: 120 parts of olive oil foaming agent, 1 part of allantoin, 5 parts of glabridin, 0.2 part of magnesium chloride, 30 parts of peony extract, 5 parts of peony root extract, 80 parts of rosemary extract, 0.01 part of mint extract and 30 parts of deionized water.
The skin care antibacterial liquid soap of this example was prepared in the same manner as in example 1.
Comparative example 1
The liquid soap of this example was prepared in the same manner as in example 1 except that the peony extract was not contained.
Comparative example 2
The liquid soap of this example was prepared in the same manner as in example 1 except that the peony root extract was not contained.
Comparative example 3
The liquid soap of this example was prepared in the same manner as in example 1, except that it did not contain rosemary extract.
Comparative example 4
The liquid soap of this example was prepared in the same manner as in example 1 except that the mint extract was not contained.
Examples of the experiments
1. Sensory evaluation of liquid soap
The volunteers were recruited to perform sensory evaluation of the liquid soap, and the odor, lather, rinse level, wettability and viscosity of the liquid soap were evaluated for each of men and women, respectively, and the evaluation results are shown in table 1 below.
TABLE 1 sensory evaluation results of liquid soap
| Test sample | Evaluation results |
| Example 1 liquid soap | Fragrance; the foam is rich and fine; easy to wash; mild in nature and moderate in consistency |
| Example 2 liquid soap | Fragrance; the foam is rich and fine; easy to wash; mild in nature and moderate in consistency |
| Example 3 liquid soap | Fragrance; the foam is rich and fine; easy to wash; mild in nature and moderate in consistency |
Therefore, the liquid soap disclosed by the invention is mild in property, rich and fine in foam, moderate in consistency, easy to wash and good in use comfort level.
2. Evaluation of physical and chemical Properties of liquid soap
(1) Testing of foam properties of liquid soap
Respectively weighing peony liquid soap, placing into a beaker, adding 10mL of distilled water, stirring with a glass rod, transferring into a 50mL measuring cylinder with a plug, covering the plug, shaking for 30 times, immediately measuring the bubble height with a graduated scale, and marking as H1And after 30min, measuring the height of the measuring cylinder again by using the graduated scale and recording as H2The results were recorded and calculated for foam stability and are shown in table 2 below.
Foam stability calculation formula: foam stability (%) ═ H2/H1×100％。
TABLE 2 foam stability results
| Test sample | Foam stability (%) |
| Example 1 liquid soap | 91.30 |
| Example 2 liquid soap | 95.83 |
| Example 3 liquid soap | 88.39 |
As can be seen from the data in table 2, the foam stability of the liquid soap of the present invention is greater than 88%, which indicates that the liquid soap of the present invention has good foam stability.
(2) Testing of stain removal Performance of liquid soap
Cutting absorbent cotton gauze into gauze with the same size of 10 × 10cm by using a pair of scissors, taking lipstick from a medical cotton swab, uniformly coating the lipstick on the gauze, and airing; weighing 1g of peony liquid soap, putting into a beaker, adding 10mL of tap water, and uniformly stirring with a glass rod; the gauze coated with the lipstick was respectively placed in a peony liquid soap beaker and soaked for 30min, taken out, washed clean with tap water, naturally dried and observed for its decontamination effect, and the results are shown in fig. 1.
As can be seen from the results shown in fig. 1, the liquid soap of the present invention has good detergency, and can satisfy the detergency requirement of people.
(3) Determination of pH value of liquid soap
1g of peony liquid soap is weighed and placed in a beaker, 10mL of freshly boiled and cooled deionized water is added and uniformly stirred, and the results are measured by a pH meter and are shown in the following table 3.
TABLE 3 determination of pH of liquid soap
| Test sample | pH value |
| Example 1 liquid soap | 6.23 |
| Example 2 liquid soap | 6.6 |
| Example 3 liquid soap | 6.9 |
As can be seen from the results in Table 3, the liquid soap of the present invention has a pH of weak acidity, which is similar to the pH of the skin surface (between 6.0 and 7.0), and is mild in nature and does not cause irritation to the skin.
(4) Determination of heat and cold resistance of liquid soap
10g of the liquid soap is put into a penicillin bottle and then put into a high-low temperature experimental box to be observed for 24 hours at the set temperature of 40 +/-1 ℃ and (-5 to-10 ℃) and the measurement results are shown in the following table 4.
TABLE 4 determination results of heat and cold resistance of liquid soap
As can be seen from the data in Table 4, the liquid soap of the present invention is transparent and has no flocculation and delamination phenomena after being placed at 40 +/-1 ℃ and-5 to-10 ℃ for 24 hours and being recovered to room temperature, which indicates that the liquid soap has good stability.
(5) Viscosity test of liquid soap
50mL of the liquid soap is placed in a beaker, the viscosity of the liquid soap at room temperature is measured by a digital display viscometer (No. 3 rotor, rotating speed 60rpm), and the experimental results are recorded as shown in Table 5 below.
TABLE 5 measurement of viscosity of liquid soap
| Test sample | Viscosity (cp) |
| Example 1 liquid soap | 2034.83 |
| Example 2 liquid soap | 2194.16 |
| Example 3 liquid soap | 1318.33 |
Therefore, the liquid soap has moderate viscosity and comfortable use feeling.
3. Evaluation of antibacterial Properties of liquid soap
Placing beef extract, NaCl, peptone and agar in a beaker, boiling, dissolving, cooling, subpackaging in a culture dish, and sterilizing (121 deg.C, 20 min); and taking the staphylococcus aureus suspension for inoculation and culture. Round paper pieces with the diameter of 6mm are taken, autoclaved and then respectively placed in the liquid soap prepared in the examples 1-3 and the comparative examples 1-4 to be soaked for 30min, and the paper pieces are clamped by sterile tweezers and placed in a drying oven at the temperature of 37 ℃. The dried paper sheets are pasted in a culture dish which is inoculated with staphylococcus aureus, slightly pressed by using sterile forceps, inverted and placed in an incubator at 37 ℃ for culturing for 24 hours, the size of the inhibition zone is observed, the size of the inhibition zone is measured by a scale, and the results are shown in the attached figure 2 and the following table 6 respectively.
TABLE 6 bacteriostatic Properties of the comparative examples
| Test sample | Size of bacteriostatic circle (mm) |
| Comparative example 1 | 22 |
| Comparative example 2 | 15 |
| Comparative example 3 | 14 |
| Comparative example 4 | 17 |
As can be seen from the results in FIG. 2, the diameter of the zone of inhibition of Staphylococcus aureus by the liquid soap of the present invention is about 25mm, which indicates that the liquid soap of the present invention has good antibacterial performance.
The above embodiments of the present invention are described in detail, and the principle and the implementation of the present invention are explained by applying specific embodiments, and the above description of the embodiments is only used to help understanding the method of the present invention and the core idea thereof; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed, and in summary, the content of the present specification should not be construed as a limitation to the present invention.
Claims (10)
1. The peony skin-care antibacterial composition is characterized by comprising the following raw materials in parts by weight: 3-120 parts of surfactant, 1-20 parts of humectant, 0.05-5 parts of skin conditioner, 0.2-3 parts of viscosity regulator, 2-30 parts of peony extract, 5-40 parts of peony root extract, 4-80 parts of rosemary extract, 0.01-1 part of mint extract and 30-100 parts of water.
2. A peony skin-care antibacterial composition according to claim 1, characterized in that: the composite material comprises the following raw materials in parts by weight: 27 parts of surfactant, 1.1 parts of humectant, 0.1 part of skin conditioner, 1 part of viscosity regulator, 5 parts of peony extract, 5 parts of peony root extract, 10 parts of rosemary extract, 0.2 part of mint extract and 50 parts of water.
3. The peony skin-care antibacterial composition according to claim 1 or 2, wherein the peony extract is an ethanol extract of peony.
4. The peony skin-care antibacterial composition according to any one of claims 1 to 3, wherein the peony root extract is an ethanol extract of peony root bark.
5. A peony skin-care antibacterial composition according to any one of claims 1-4, wherein said rosemary extract is an aqueous extract of rosemary leaves.
6. A peony skin-care antibacterial composition according to any one of claims 1 to 5, wherein said mint extract is an aqueous extract of mint leaves.
7. A peony skin-care antibacterial composition according to any one of claims 1-6, characterized in that:
the surfactant comprises one or a mixture of more of coco glucoside, coconut fatty acid diethanolamide, fatty alcohol ether ester sodium sulfate, cocamidopropyl betaine, olive oil foaming agent, lauramidopropyl betaine, sodium cocoeth sulfate, PEG-7 glyceryl cocoate, sodium lauroyl amino acid and sodium cocoyl malic amino acid;
the humectant comprises one or more of glycerol, butanediol, pentanediol, hexanediol, propylene glycol, polyethylene glycol, xylitol, polypropylene glycol, sorbitol, sodium pyrrolidone carboxylate, erythritol, panthenol, hyaluronic acid, betaine, allantoin, and trehalose;
the skin conditioner comprises one or more of dipotassium glycyrrhizinate, nicotinamide, glabridin, glycyrrhetinic acid, and arbutin;
the viscosity regulator comprises one or more of sodium sulfate, sodium chloride and magnesium chloride.
8. Use of the peony skin care antibacterial composition according to any one of claims 1 to 6 for preparing a skin care antibacterial liquid soap.
9. A skin care antibacterial liquid soap prepared based on the peony skin care antibacterial composition of any one of claims 1-6.
10. The method for preparing the skin-care antibacterial liquid soap as claimed in claim 9, which is characterized by comprising the steps of fully and uniformly mixing selected amounts of the surfactant, water, the skin conditioner, the humectant, the viscosity regulator, the peony flower extract, the peony root extract, the rosemary extract and the mint extract in sequence, and degassing to obtain the required skin-care antibacterial liquid soap.
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060165644A1 (en) * | 2002-08-14 | 2006-07-27 | Fancl Corporation | Cosmetics |
| CN103751058A (en) * | 2014-01-10 | 2014-04-30 | 河南科技大学 | Peony skin care product and preparation method thereof |
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