CN114652628A - Anti-aging cream for beautifying chest and body and enhancing skin immune barrier and preparation method thereof - Google Patents

Anti-aging cream for beautifying chest and body and enhancing skin immune barrier and preparation method thereof Download PDF

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CN114652628A
CN114652628A CN202210332138.6A CN202210332138A CN114652628A CN 114652628 A CN114652628 A CN 114652628A CN 202210332138 A CN202210332138 A CN 202210332138A CN 114652628 A CN114652628 A CN 114652628A
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陈剑英
陈伟杰
王秀清
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Guangzhou Tenglin Biotechnology Co ltd
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Guangzhou Tenglin Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention relates to an anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier, which belongs to the technical field of skin care products and comprises the following raw materials in parts by weight: 48.4292-53.4592 parts of P1 phase, 11.1-12.1 parts of P2 phase, 1.3 parts of P3 phase, 0.2 part of P4 phase, 3.8008-6.4008 parts of P5 phase, 8.4-11.3 parts of P6 phase and 16.64-22.08 parts of P7 phase, and in order to reduce the irritation of the cream to the chest, the cream is mainly prepared from pure plant essences, wherein the pure plant essences are medicinal plant raw materials such as kudzu root extract, papaya fruit extract, lucid ganoderma extract, long-noded dioscorea root extract, oldenlandia diffusa extract, total radix cimicifugae extract, pseudo-ginseng extract and hydrolyzed soybean extract, so that the safety and efficacy of the cream are improved, and the efficacy active substances are better absorbed by the skin by adopting a tetrahydropiperine natural penetration enhancer, and the cream has the characteristics of high safety, high mildness and the like.

Description

Anti-aging cream for beautifying chest and body and enhancing skin immune barrier and preparation method thereof
Technical Field
The invention belongs to the technical field of skin care products, and particularly relates to anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier and a preparation method thereof.
Background
The breast massage anti-aging cream solves the problem of breasts fundamentally, adopts a perfect combination of a pure natural plant formula and a modern biotechnology, contains natural active enzyme components extracted from ginseng, Thailand wild radix puerariae and the like, is compounded with polypeptide and a plant-free permeation promoting technology, acts on breast tissues at 360 degrees without dead angles through simple smearing and massage, directly permeates and quickly absorbs the breast tissues, deeply improves the blood circulation of the breasts, comprehensively nourishes the activity of breast cells, polymerizes fat in the breasts, promotes the breasts to enter a secondary development stage, effectively strengthens suspended ligaments and a reticular supporting structure of the breasts in a short time, strengthens the breast enlarging effect, and ensures that the breasts become fine, smooth, full and firm.
The research shows that the 'cream' is easily absorbed by the skin of a human body and is easy to volatilize, while the cream rich in heparin sodium and piperine has double absorption force, and the volatilization amount is reduced to the minimum in the same time. The cream is rich in piperine, can enable the cream to be free and to be separated from the breast cortex and breast tissue cells, has the penetrating and absorbing capacity more than 20 times that of common cream, has certain adsorption capacity, can achieve the effects of close attachment and continuous absorption with breast tissue cells, effectively approaches 100 percent absorption, and comprehensively activates dormant breast cells.
At present, the penetration enhancer laurocapram is generally used in cosmetics such as skin cream due to low price, however, the penetration enhancer laurocapram has large irritation to skin and low safety. At present, the consumption concepts of environmental protection, safety and no public nuisance are increasingly deeply bored, along with the continuous improvement of cosmetic technology and laws and regulations, the safety requirements of cosmetics such as skin care emulsion are higher and higher, and the skin care cream which is safe, mild, non-irritant and good in effect represents the development direction of the skin care cream in the future, and the traditional skin care cream adopting penetration enhancer laurocapram is difficult to meet the requirements.
Disclosure of Invention
In order to solve the technical problems mentioned in the background technology, the invention provides anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier and a preparation method thereof.
The purpose of the invention can be realized by the following technical scheme:
an anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier comprises the following raw materials in parts by weight: 48.4292-53.4592 parts of P1 phase, 11.1-12.1 parts of P2 phase, 1.3 parts of P3 phase, 0.2 part of P4 phase, 3.8008-6.4008 parts of P5 phase, 8.4-11.3 parts of P6 phase and 16.64-22.08 parts of P7 phase;
the P1 phase comprises the following components in parts by weight: 39.4492-42.6092 parts of water, 0.03 part of ethylene diamine tetraacetic acid, 0.2-0.5 part of tetrahydro-methylpyrimidine carboxylic acid, 0.2 part of carbomer, 3 parts of glycerol, 1 part of propylene glycol, 0.02-0.05 part of sodium hyaluronate, 2-4 parts of ganoderma extract solution, 0.1-0.3 part of hydrolyzed soybean oil solution, 0.5-1.5 parts of ginseng extract solution, 0.1 part of heparin sodium and 0.1 part of long-hair dioscorea root extract solution;
further, the ganoderma lucidum extract solution is prepared from water, ganoderma lucidum extract and phenoxyethanol according to a mass ratio of 96.6: 3.0: 0.4 mixing;
further, the hydrolyzed soybean oil solution is prepared from water, a hydrolyzed soybean extract and phenoxyethanol according to a mass ratio of 96.6: 3.0: 0.4 mixing;
further, the ginseng extract solution is prepared from water, ginseng root extract and phenoxyethanol according to a mass ratio of 96.5:3: 0.5;
further, the weight ratio of the long-hair dioscorea root extract solution to the butanediol to the long-hair dioscorea root extract is 13: 85: 2, mixing;
the P2 phase comprises the following components in parts by weight: 2 parts of a first emulsified composition, 0.8 part of a second emulsified composition, 2 parts of cetostearyl alcohol, 1 part of jojoba seed oil, 1-2 parts of evening primrose oil, 1 part of polydimethylsiloxane, 3 parts of an emollient, 2 parts of squalane, 3 parts of isopropyl myristate and 0.1 part of bisabolol;
further, the first emulsifying composition is prepared from cetearyl alcohol, cetearyl glucoside, water and glucose according to a mass ratio of 80: 19.6: 0.1: 0.3, mixing;
further, the second emulsifying composition is prepared by mixing glycerol stearate and PEG-100 stearate according to the mass ratio of 13: 7;
further, the softening agent is prepared from cyclopentadidimethyl siloxane and cyclohexasiloxane according to a mass ratio of 7: 3, mixing;
the P3 phase comprises the following components in parts by weight: 0.3 part of tetrahydropiperine and 1 part of propylene glycol;
the P4 phase comprises the following components in parts by weight: 0.2 portion of triethanolamine
The P5 phase comprises the following components in parts by weight: 0.5 part of p-hydroxyacetophenone, 0.5 part of 1, 2-hexanediol, 0.5 part of antioxidant component, 0.25 part of antiseptic synergistic component, 1 part of propylene glycol, 0.1-0.5 part of moisturizing component, 172000.08 parts of CI and 1-4 parts of crocus sativus extract solution;
further, the antioxidant component is prepared by mixing ethyl hexyl glycerol and tocopherol according to the mass ratio of 99.9: 0.1;
further, the antiseptic synergistic component is prepared by mixing 1, 3-propylene glycol and caprylyl hydroximic acid according to the mass ratio of 92.5: 7.5;
further, the moisture-keeping component is formed by mixing glycerol and glycerol glucoside according to the mass ratio of 1: 1;
further, the crocus extract solution is prepared by mixing water, crocus extract and phenoxyethanol according to the mass ratio of 96.6:3: 0.4;
the P6 phase comprises the following components in parts by weight: 0.1-1 part of oldenlandia diffusa extract solution, 2.5-4 parts of total-shaped Shengmagen extract solution, 2-4 parts of pseudo-ginseng extract solution, 0.1-0.6 part of water retention component and 1.5-5 parts of soybean isoflavone solution;
furthermore, the oldenlandia diffusa extract solution is prepared by mixing water, oldenlandia diffusa extract and phenoxyethanol according to the mass ratio of 96.5:3: 0.4;
further, the total rhizoma cimicifugae extract solution is prepared by mixing water, the total rhizoma cimicifugae extract and phenoxyethanol according to the mass ratio of 96.5:3: 0.5;
further, the pseudo-ginseng extract solution is prepared from water, pseudo-ginseng extract and phenoxyethanol according to a mass ratio of 96.6:3:0.4 mixing;
further, the water retention component is formed by mixing water, saccharide isomerate, sodium benzoate and citric acid according to the mass ratio of 98.4:0.9:0.6: 0.1;
further, the soybean isoflavone solution is prepared by mixing soybean isoflavone and polyethylene glycol-4 according to a mass ratio of 1: 9 mixing the components;
the P7 phase comprises the following components in parts by weight: 3-8 parts of kudzu root extract solution, 3-6 parts of papaya fruit extract solution, 0.1-0.5 part of repairing component, 0.01-0.2 part of third emulsifying composition, 0.01-0.2 part of anti-aging component, 0.1-0.5 part of first nutrient component, 5-11 parts of second nutrient component, 0.02-0.05 part of vanillyl butyl ether and 0.01-0.03 part of rosa damascena flower oil;
further, the kudzu root extract solution is prepared by mixing water, kudzu root extract and phenoxyethanol according to the mass ratio of 96.5:3: 0.5;
further, the papaya fruit extract solution is prepared by mixing water, papaya fruit extract and phenoxyethanol according to a ratio of 96.6:3: 0.4;
further, the repair component is formed by mixing water, phenoxyethanol, ethylhexyl glycerol and arginine/lysine polypeptide according to the mass ratio of 99.4:0.5:0.07: 0.003;
further, the third emulsifying composition is prepared by mixing glycerol, water, butanediol, polysorbate-20, carbomer and palmitoyl pentapeptide-4 according to the mass ratio of 67:26.67:6:0.5:0.2: 0.01;
further, the anti-aging component is prepared by mixing water, caprylyl glycol and acetyl hexapeptide-8 according to the mass ratio of 99.45:0.5: 0.05;
further, the first nutritional component is formed by mixing water, oligopeptide-1, trehalose, p-hydroxyacetophenone and 1.2-hexanediol according to a mass ratio of 84:10:5:0.5: 0.5;
further, the second nutritional component is formed by mixing water, butanediol, oat beta-glucan, 1, 2-hexanediol and capryl glycol according to the mass ratio of 86.8:10:1:2: 0.2;
the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier is prepared by the following steps:
firstly, cleaning and disinfecting production equipment, tools and containers, adding a P1 phase into a reaction kettle, completely dispersing, heating to 82-85 ℃, and completely stirring and dissolving;
secondly, adding the P2 phase into a stirring pot, and heating to 78-82 ℃ to completely dissolve;
thirdly, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 5-8 minutes, stirring for dissolving, preserving heat for 15-20 minutes, and defoaming to obtain a first composition;
fourthly, cooling water is boiled, when the temperature of the first composition is reduced to 64-66 ℃, pre-dissolved P3 and P4 phases (pre-heated to 60 +/-2 ℃ for complete dissolution) are sequentially added, the P5 phase is added after uniform stirring, the temperature is continuously reduced to below 45 ℃, the P6 phase (pre-heated to 60 +/-2 ℃ for complete dissolution) and the P7 phase are sequentially added, and uniform stirring is carried out;
and fifthly, sampling and detecting, closing cooling water when the temperature is 38-40 ℃ after the cream is qualified, and discharging the cooling water through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
The core component has the following functions:
core component 1: rosa DAMASCENA (ROSA DAMASCENA) flower oil can enhance the strength of blood vessels, can prevent skin red blood filaments, and has the promotion effect on the generation of ceramide, which shows that the ceramide content in sebum can be increased, so that the skin softening effect is achieved; the inhibition effect on elastase shows that the cosmetic has anti-wrinkle performance, and is used as a 100% pure natural and very safe cosmetic active raw material.
Core component 2: palmitoyl pentapeptide-4, palmitoyl pentapeptide-4 is an anti-aging component, can penetrate dermis to increase collagen, and can reverse skin aging process through reconstruction from inside to outside; palmitoyl pentapeptide-4 stimulates the proliferation of collagen, elastic fibers and hyaluronic acid, improves the moisture content and water locking degree of skin, increases the thickness of the skin and reduces wrinkles, pentapeptide has five amino acids, which is one of the most popular collagen peptides in cosmetics, and palmitoyl pentapeptide-4 can increase the absorption effect.
Core component 3: the acetyl hexapeptide-8 and the acetyl hexapeptide-8 are bioactive polypeptides which can reduce existing facial wrinkles and effectively prevent new wrinkles, and the research of human volunteers shows that the acetyl hexapeptide-8 has excellent anti-wrinkle effect, the wrinkles around eyes are reduced by up to 17% after 15 days of use, and the wrinkles are reduced by 27% after 30 days of use, thereby showing the surprising effect on the anti-wrinkle activity, and the acetyl hexapeptide-8 have great breakthrough in the cosmetic science field, can lighten the depth of the wrinkles, are external-use botulinum toxin substitutes for inhibiting the expression muscle contraction, are used for reducing the wrinkles, particularly forehead and eye circumference, do not generate side effects, and are recognized as high-efficiency anti-wrinkle components.
Core component 4: the ectoin is an amino acid derivative and a cell water retention component, can stimulate the generation of aminoglucan, promotes the generation and construction of protein polysaccharide (such as gelatinous protein network and sugar serving as a bracket and an intercellular shock absorber) in an extracellular matrix, continuously improves the water retention capacity of skin epidermal cells and a natural moisture-retaining barrier, does not immediately reduce the water retention capacity of the skin even after the skin is stopped, is higher than a control group after the skin is stopped for one week, is a very excellent moisture-retaining barrier repairing component, and is used as a 100% pure natural and very safe cosmetic active raw material.
Core component 5: arginine/lysine polypeptide promotes the regeneration of fibroblasts, stimulates the synthesis of collagen and restores the elasticity of skin, and the arginine/lysine polypeptide is biologically simulated conotoxin peptide, provides a strong muscle relaxation effect through sequencing and artificial synthesis and provides rapid and instant anti-wrinkle.
Core component 6: tetrahydropiperine, a safe, highly effective, natural penetration enhancer, increases the "rate" of penetration of the active into the skin in a minimum amount of time to allow better absorption of the active by the skin.
The invention has the beneficial effects that:
the invention provides an anti-aging cream for beautifying chest and body and enhancing skin immune barrier, which is prepared from pure plant essences serving as raw materials in order to reduce stimulation of cream on chest skin to zero, wherein the raw materials comprise medicinal plant raw materials such as kudzu root extract, papaya extract, lucid ganoderma extract, dioscorea villosa root extract, oldenlandia diffusa extract, total gnetum root extract, pseudo-ginseng extract and hydrolyzed soybean extract, so as to improve safety and efficacy of the cream.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
An anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier comprises the following raw materials: a P1 phase, a P2 phase, a P3 phase, a P4 phase, a P5 phase, a P6 phase, a P7 phase, as shown in Table 1;
the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier is prepared by the following steps:
step one, cleaning and disinfecting production equipment, tools and containers, adding a P1 phase into a reaction kettle, completely dispersing, heating to 82 ℃, and completely stirring and dissolving;
secondly, adding the P2 phase into a stirring pot, and heating to 78-82 ℃ to completely dissolve;
step three, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 5 minutes, stirring for dissolving, preserving heat for 15 minutes, and defoaming to obtain a first composition;
fourthly, cooling water is boiled, when the temperature of the first composition is reduced to 64 ℃, pre-dissolved P3 and P4 phases (pre-heated to 60 +/-2 ℃ for complete dissolution) are sequentially added, the P5 phase is added after uniform stirring, the temperature is continuously reduced to below 45 ℃, the P6 phase (pre-heated to 60 +/-2 ℃ for complete dissolution) and the P7 phase are sequentially added, and the uniform stirring is carried out;
and fifthly, sampling and detecting, closing cooling water when the temperature is 38 ℃ after the cream is qualified, and discharging the cooling water through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
Example 2
An anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier comprises the following raw materials: a P1 phase, a P2 phase, a P3 phase, a P4 phase, a P5 phase, a P6 phase, a P7 phase, as shown in Table 1;
the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier is prepared by the following steps:
step one, cleaning and disinfecting production equipment, tools and containers, adding a P1 phase into a reaction kettle, completely dispersing, heating to 84 ℃, and completely stirring and dissolving;
secondly, adding the P2 phase into a stirring pot, and heating to 78-82 ℃ to completely dissolve;
thirdly, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 7 minutes, stirring for dissolving, preserving heat for 18 minutes, and defoaming to obtain a first composition;
fourthly, cooling water is boiled, when the temperature of the first composition is reduced to 65 ℃, pre-dissolved P3 and P4 phases (pre-heated to 60 +/-2 ℃ for complete dissolution) are sequentially added, the P5 phase is added after uniform stirring, the temperature is continuously reduced to below 45 ℃, the P6 phase (pre-heated to 60 +/-2 ℃ for complete dissolution) and the P7 phase are sequentially added, and the uniform stirring is carried out;
and fifthly, sampling and detecting, closing cooling water when the temperature is 39 ℃ after the cream is qualified, and discharging the cooling water through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
Example 3
An anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier comprises the following raw materials: a P1 phase, a P2 phase, a P3 phase, a P4 phase, a P5 phase, a P6 phase, a P7 phase, as shown in Table 1;
the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier is prepared by the following steps:
step one, cleaning and disinfecting production equipment, tools and containers, adding a P1 phase into a reaction kettle, completely dispersing, heating to 85 ℃, and completely stirring and dissolving;
secondly, adding the P2 phase into a stirring pot, and heating to 82 ℃ to completely dissolve;
thirdly, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 8 minutes, stirring for dissolving, preserving heat for 20 minutes, and defoaming to obtain a first composition;
fourthly, cooling water is boiled, when the temperature of the first composition is reduced to 66 ℃, pre-dissolved P3 and P4 phases (pre-heated to 60 +/-2 ℃ for complete dissolution) are sequentially added, the P5 phase is added after uniform stirring, the temperature is continuously reduced to below 45 ℃, the P6 phase (pre-heated to 60 +/-2 ℃ for complete dissolution) and the P7 phase are sequentially added, and the uniform stirring is carried out;
and fifthly, sampling and detecting, closing cooling water when the temperature is 40 ℃ after the cream is qualified, and discharging the cooling water through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
Example 4
An anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier comprises the following raw materials: a P1 phase, a P2 phase, a P3 phase, a P4 phase, a P5 phase, a P6 phase, a P7 phase, as shown in Table 1;
the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier is prepared by the following steps:
step one, cleaning and disinfecting production equipment, tools and containers, adding a P1 phase into a reaction kettle, completely dispersing, heating to 85 ℃, and completely stirring and dissolving;
secondly, adding the P2 phase into a stirring pot, and heating to 80 ℃ to completely dissolve;
thirdly, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 8 minutes, stirring for dissolving, preserving heat for 20 minutes, and defoaming to obtain a first composition;
fourthly, cooling water is boiled, when the temperature of the first composition is reduced to 65 ℃, pre-dissolved P3 and P4 phases (pre-heated to 60 +/-2 ℃ for complete dissolution) are sequentially added, the P5 phase is added after uniform stirring, the temperature is continuously reduced to below 45 ℃, the P6 phase (pre-heated to 60 +/-2 ℃ for complete dissolution) and the P7 phase are sequentially added, and the uniform stirring is carried out;
and fifthly, sampling and detecting, closing cooling water when the temperature is 39 ℃ after the cream is qualified, and discharging the cooling water through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
TABLE 1
Figure BDA0003573468470000091
Figure BDA0003573468470000101
Figure BDA0003573468470000111
100 office workers (100 women, age 25-50 years) were selected for testing, and the activation creams of examples 1-4 were each tested on 100 subjects. The subject is smeared on the chest with the activation cream every night and massaged evenly until being absorbed; the revitalizing cream is continuously used for four weeks, the subjects score the chest skin effect according to the feelings of the subjects, the score is 5 points, 1 point is the worst, 3 points are moderate, 5 points are the best, the higher the score is, the better the effect is, the score is 1-2 points before the use of 100 subjects, and the effect evaluation results after the use are as shown in the following table 2:
TABLE 2
Examples Moistening degree Q elasticity Irritation property Compactness Results
1 4 3 3 2 3
2 5 4 4 3 4
3 3 3 3 2 2.75
4 4 3 4 3 3.5
The test results in table 2 show that the chest relaxation problem is significantly favored by the activation cream of the invention, and all the subjects showed that the activation cream of the invention is favorable, the product is safe and mild without allergy, and 80% of the subjects continue to use regularly after two weeks; the added arginine/lysine polypeptide, palmitoyl pentapeptide-4, acetyl hexapeptide-8 and the radix puerariae extract have the effects of enhancing the skin elasticity, keeping the skin water locking capacity and compacting the skin, and the skin can be effectively compacted to be moist, smooth and elastic.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing is illustrative and explanatory only and is not intended to be exhaustive or to limit the invention to the precise embodiments described, and various modifications, additions, and substitutions may be made by those skilled in the art without departing from the scope of the invention or exceeding the scope of the claims.

Claims (8)

1. The anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier is characterized by comprising the following raw materials in parts by weight: 48.4292-53.4592 parts of P1 phase, 11.1-12.1 parts of P2 phase, 1.3 parts of P3 phase, 0.2 part of P4 phase, 3.8008-6.4008 parts of P5 phase, 8.4-11.3 parts of P6 phase and 16.64-22.08 parts of P7 phase;
the P1 phase comprises the following components in parts by weight: 39.4492-42.6092 parts of water, 0.03 part of ethylene diamine tetraacetic acid disodium, 0.2-0.5 part of tetrahydro-methyl pyrimidine carboxylic acid, 0.2 part of carbomer, 3 parts of glycerol, 1 part of propylene glycol, 0.02-0.05 part of sodium hyaluronate, 2-4 parts of lucid ganoderma extract solution, 0.1-0.3 part of hydrolyzed soybean oil solution, 0.5-1.5 parts of ginseng extract solution, 0.1 part of heparin sodium and 0.1 part of long dioscorea villosa root extract solution;
the P2 phase comprises the following components in parts by weight: 2 parts of a first emulsified composition, 0.8 part of a second emulsified composition, 2 parts of cetostearyl alcohol, 1 part of jojoba seed oil, 1-2 parts of evening primrose oil, 1 part of polydimethylsiloxane, 3 parts of an emollient, 2 parts of squalane, 3 parts of isopropyl myristate and 0.1 part of bisabolol;
the P3 phase comprises the following components in parts by weight: 0.3 part of tetrahydropiperine and 1 part of propylene glycol;
the P4 phase comprises the following components in parts by weight: 0.2 part of triethanolamine;
the P5 phase comprises the following components in parts by weight: 0.5 part of p-hydroxyacetophenone, 0.5 part of 1, 2-hexanediol, 0.5 part of antioxidant component, 0.25 part of antiseptic synergistic component, 1 part of propylene glycol, 0.1-0.5 part of moisturizing component, 172000.08 parts of CI and 1-4 parts of crocus sativus extract solution;
the P6 phase comprises the following components in parts by weight: 0.1-1 part of oldenlandia diffusa extract solution, 2.5-4 parts of total-shaped Shengmagen extract solution, 2-4 parts of pseudo-ginseng extract solution, 0.1-0.6 part of water retention component and 1.5-5 parts of soybean isoflavone solution;
the P7 phase comprises the following components in parts by weight: 3-8 parts of kudzu root extract solution, 3-6 parts of papaya fruit extract solution, 0.1-0.5 part of repairing component, 0.01-0.2 part of third emulsion composition, 0.01-0.2 part of anti-aging component, 0.1-0.5 part of first nutrient component, 5-11 parts of second nutrient component, 0.02-0.05 part of vanillyl butyl ether and 0.01-0.03 part of rosa damascena flower oil.
2. The anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier according to claim 1, wherein the ganoderma lucidum extract solution is prepared from water, ganoderma lucidum extract and phenoxyethanol according to a mass ratio of 96.6: 3.0: 0.4, and the hydrolyzed soybean oil solution is prepared by mixing water, hydrolyzed soybean extract and phenoxyethanol according to a mass ratio of 96.6: 3.0: 0.4, and the ginseng extract solution is prepared by mixing water, ginseng root extract and phenoxyethanol according to a mass ratio of 96.5:3:0.5, wherein the weight ratio of the long-hair dioscorea root extract solution to the butanediol to the long-hair dioscorea root extract is 13: 85: 2, mixing the components.
3. The anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier as claimed in claim 1, wherein the first emulsifying composition is prepared from cetearyl alcohol, cetearyl glucoside, water and glucose in a mass ratio of 80: 19.6: 0.1: 0.3, mixing; the second emulsifying composition is formed by mixing glycerol stearate and PEG-100 stearate according to the mass ratio of 13: 7.
4. The anti-aging cream for beautifying breasts and enhancing skin immune barriers as claimed in claim 1, wherein the anti-oxidation component is prepared by mixing ethylhexyl glycerol and tocopherol according to a mass ratio of 99.9:0.1, the preservative synergistic component is prepared by mixing 1, 3-propylene glycol and caprylyl hydroximic acid according to a mass ratio of 92.5:7.5, and the moisturizing component is prepared by mixing glycerol and glycerol glucoside according to a mass ratio of 1: 1.
5. The anti-aging cream for beautifying breast and enhancing skin immune barrier according to claim 1, characterized in that the oldenlandia diffusa extract solution is formed by mixing water, oldenlandia diffusa extract and phenoxyethanol according to a mass ratio of 96.5:3:0.4, the total rhizoma cimicifugae extract solution is formed by mixing water, total rhizoma cimicifugae extract and phenoxyethanol according to a mass ratio of 96.5:3:0.5, and the panax notoginseng extract solution is formed by mixing water, panax notoginseng extract and phenoxyethanol according to a mass ratio of 96.6:3:0.4, the water retention component is formed by mixing water, saccharide isomerate, sodium benzoate and citric acid according to the mass ratio of 98.4:0.9:0.6:0.1, the soybean isoflavone solution is formed by mixing soybean isoflavone and polyethylene glycol-4 according to the mass ratio of 1: 9, and mixing.
6. The anti-aging cream for beautifying the chest and body and enhancing the skin immune barrier as claimed in claim 1, wherein the repairing component is formed by mixing water, phenoxyethanol, ethylhexyl glycerol and arginine/lysine polypeptide according to a mass ratio of 99.4:0.5:0.07: 0.003.
7. The cream of claim 1, wherein the anti-aging component is prepared by mixing water, caprylyl glycol and acetyl hexapeptide-8 according to a mass ratio of 99.45:0.5:0.05, the first nutritional component is prepared by mixing water, oligopeptide-1, trehalose, p-hydroxyacetophenone and 1.2-hexanediol according to a mass ratio of 84:10:5:0.5:0.5, and the second nutritional component is prepared by mixing water, butanediol, oat beta-glucan, 1, 2-hexanediol and caprylyl glycol according to a mass ratio of 86.8:10:1:2: 0.2.
8. The method for preparing the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier according to claim 1 is characterized by comprising the following steps of:
firstly, adding a P1 phase into a reaction kettle, heating to 82-85 ℃, and stirring for dissolving;
secondly, adding the P2 phase into a stirring pot, heating to 78-82 ℃, and stirring for dissolving;
thirdly, vacuumizing the reaction kettle, adding the dissolved P2 phase into the dissolved P1 phase, homogenizing for 5-8 minutes, stirring for dissolving, preserving heat for 15-20 minutes, and defoaming to obtain a first composition;
and fourthly, cooling the first composition to 64-66 ℃, sequentially adding pre-dissolved P3 and P4 phases, uniformly stirring, adding the P5 phase, continuously cooling to below 45 ℃, sequentially adding the P6 phase and the P7 phase, uniformly stirring, and discharging through a 100-mesh filter screen to obtain the anti-aging cream for beautifying the chest and the body and enhancing the skin immune barrier.
CN202210332138.6A 2022-03-30 2022-03-30 Anti-aging cream for beautifying chest and body and enhancing skin immune barrier and preparation method thereof Pending CN114652628A (en)

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CN113952276A (en) * 2021-11-24 2022-01-21 上海小愿生物科技有限公司 Plant aromatic skin care composition with anti-aging effect and preparation method thereof

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CN111166683A (en) * 2019-12-28 2020-05-19 嘉汶化妆品(东莞)有限公司 Fullerene anti-aging antioxidant beauty and skin care cosmetic and preparation method thereof
CN111686068A (en) * 2020-05-08 2020-09-22 佐登妮丝(广州)美容化妆品有限公司 Anti-wrinkle skin-activating cream and preparation method thereof
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Application publication date: 20220624