CN114601896A - Traditional Chinese medicine composition and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition and preparation method and application thereof Download PDFInfo
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- CN114601896A CN114601896A CN202210294535.9A CN202210294535A CN114601896A CN 114601896 A CN114601896 A CN 114601896A CN 202210294535 A CN202210294535 A CN 202210294535A CN 114601896 A CN114601896 A CN 114601896A
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Classifications
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- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Botany (AREA)
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- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition and a preparation method and application thereof, wherein the traditional Chinese medicine composition comprises 5-10 parts by weight of fresh garlic and 5-10 parts by weight of dried orange peel, and the dried orange peel is soaked in 500 parts by weight of 100-fold liquid. In the composition, garlic is rich in various bioactive components and natural soil plant protein bodies with inhibiting effect on microorganisms and virus cells, and the sulfide component molecular crystalline state of the natural soil plant protein bodies is an orthorhombic system, so that the dense entanglement and winding of novel coronavirus overlong RNA can be continuously destroyed, thereby blocking the synthetic variation of coronaviruses and rapidly invading respiratory tracts, and the composition also has the effects of killing and inhibiting various bacteria and viruses and improving the immunity and resistance of organisms. The dried orange peel has the effects of regulating qi, lowering adverse qi, regulating the middle warmer, stimulating appetite, eliminating dampness and phlegm, and can form oral protein microecological flora in oral cavity under the synergistic effect of the stack state of the dried orange peel and the garlic, so as to fully destroy the rapid polymerization density of the novel coronavirus, and prevent the novel coronavirus from invading human body (respiratory system especially invading lung).
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, relates to a traditional Chinese medicine composition, a preparation method and application thereof, and particularly relates to a traditional Chinese medicine composition, a preparation method thereof and application thereof in preventing new coronavirus infection.
Background
Viruses of the genus coronavirus are enveloped, linear, single-stranded, positive-stranded RNA viruses of the genome, and a large group of viruses widely found in nature. Among them, the 2019 novel coronavirus (2019-nCoV, which causes novel coronavirus pneumonia COVID-19) is the 7 th known coronavirus capable of infecting people at present, and the novel coronavirus can be transmitted by respiratory droplets and close contact, has strong transmission capability, is not easy to prevent, and has higher infectivity, longer latency and stronger concealment. The clinical manifestations of the novel coronavirus infection are fever, hypodynamia, dry cough and gradual dyspnea, and the severe cases are acute respiratory distress syndrome, sepsis shock, metabolic acidosis and blood coagulation dysfunction which are difficult to correct, and the like.
Infection and pathogenesis of new coronavirus infections and other respiratory infectious diseases often begins with local infections of the mouth and throat of humans. Infectious bacteria, fungi or viruses, etc. adhere to the tissues of the mouth and throat where they find good conditions for propagation or specific receptors and activating enzyme systems that invade host cells, and these infectious agents are then carried by the inhaled air to the lungs, starting to form new colonies in the alveoli, attacking epithelial cells with the same characteristics. From there, the infectious agent eventually penetrates the alveolar wall into the blood circulation. Based on the characteristics of the novel coronavirus such as the aggregative morbidity, contact transmission and air droplet transmission, the prevention and treatment of the coronavirus become key points and difficulties in clinical and basic research at present.
At present, no traditional Chinese medicine composition which is simple in formula and easy to take and can prevent novel coronavirus exists in the market, and if the traditional Chinese medicine composition which is harmless to human bodies, can inhibit the replication and propagation of the novel coronavirus and can improve the virus removal efficiency in vivo is provided, huge social benefits are undoubtedly achieved.
Disclosure of Invention
Therefore, the invention aims to solve the technical problems, and provides a traditional Chinese medicine composition, a preparation method thereof and application thereof in preventing new coronavirus infection.
In order to solve the technical problems, the technical scheme of the invention is as follows:
the invention provides a traditional Chinese medicine composition which comprises, by weight, 5-10 parts of fresh garlic and 5-10 parts of dried orange peel, wherein the dried orange peel is soaked in 500 parts of liquid of 100-.
Preferably, the liquid is one of water, crystal sugar water, brown sugar water or honey water.
Preferably, the composition further comprises 30 parts of cassia bark, 30 parts of astragalus root, 30 parts of medlar, 30 parts of ginger, 30 parts of codonopsis pilosula and 10 parts of liquorice in parts by weight.
Preferably, the composition further comprises 10 parts of gypsum, 10 parts of borneol and 10 parts of honeysuckle in parts by weight.
In a second aspect, the present application provides a method for preparing the Chinese medicinal composition, which comprises the following steps:
peeling and crushing the fresh garlic;
and soaking the dried orange peel in a solution, namely a dried orange peel solution.
Preferably, the method also comprises the steps of extracting the crushed garlic in a dried orange peel solution, concentrating, and preparing pills and granules.
Preferably, the fresh garlic is subjected to a pulverization treatment by crushing or chopping.
The third aspect of the invention provides an application of the traditional Chinese medicine composition in preventing novel coronavirus infection.
Compared with the prior art, the technical scheme of the invention has the following advantages:
(1) the traditional Chinese medicine composition provided by the invention comprises 5-10 parts by weight of fresh garlic and 5-10 parts by weight of dried orange peel, wherein the dried orange peel is soaked in 500 parts by weight of liquid of 100 parts. In the composition, garlic is rich in various bioactive components, such as flavonoid and polyphenol, and natural soil plant protein bodies with inhibiting effect on microorganisms and virus cells, and sulfide component molecular crystalline state of the garlic is an orthorhombic system, so that dense entanglement of novel coronavirus ultralong RNA can be continuously destroyed, thereby blocking synthetic variation of coronaviral organisms and rapidly invading respiratory tract, and the garlic also has the effects of killing and inhibiting various bacteria and viruses and improving immunity and resistance of organisms. The dried orange peel has the effects of regulating qi, lowering adverse qi, regulating the middle warmer, stimulating appetite, eliminating dampness and phlegm, and can form oral protein microecological flora in oral cavity under the synergistic effect of the dried orange peel and garlic, so as to fully destroy the rapid polymerization density of the novel coronavirus, and prevent the novel coronavirus from invading human body (respiratory system especially invading lung).
(2) The traditional Chinese medicine composition provided by the invention further comprises 30 parts of cassia bark, 30 parts of astragalus root, 30 parts of medlar, 30 parts of ginger, 30 parts of codonopsis pilosula and 10 parts of liquorice in parts by weight. The cassia bark has the effects of warming middle-jiao to dispel cold and regulating qi to alleviate pain, the astragalus has the effects of tonifying qi, strengthening exterior, arresting sweating and tonifying lung and spleen, the ginger has the effects of relieving exterior syndrome, dispelling cold, warming middle-jiao to arrest vomiting, warming lung to relieve cough and detoxifying, the codonopsis pilosula has the effects of tonifying middle-jiao and qi, tonifying spleen and benefiting lung, the liquorice has the effects of tonifying spleen, tonifying qi, clearing heat, detoxifying, eliminating phlegm, relieving cough, relieving spasm and pain and harmonizing the medicines, the components have synergistic effect with the garlic and the dried orange peel, the invasion of new corona viruses can be prevented, and the health-care effect is realized.
(3) The traditional Chinese medicine composition provided by the invention further comprises 10 parts of gypsum, 10 parts of borneol and 10 parts of honeysuckle in parts by weight. Wherein, the plaster has the efficacies of clearing heat and purging fire, relieving restlessness and quenching thirst, the borneol and the honeysuckle have the efficacies of clearing heat and removing toxicity, and the components can effectively solve the problems of preventing and treating infectious diseases such as viral cold, viral pneumonia and the like by the synergistic effect with the garlic and the dried orange peel.
Detailed Description
In order that the present disclosure may be more readily and clearly understood, reference will now be made in detail to the present disclosure as illustrated in the accompanying drawings.
Example 1
This example provides a Chinese medicinal composition comprising 5g of fresh garlic and 5g of dried orange peel, which is soaked in 100g of water to obtain dried orange peel water.
The preparation method of the composition comprises the following steps:
s1, peeling fresh garlic, grinding and crushing;
s2, soaking pericarpium Citri Reticulatae in water to obtain pericarpium Citri Reticulatae water.
The composition is administered by chewing pulverized fresh garlic slowly to the pharynx, and then administering dried orange peel water.
The traditional Chinese medicine composition provided by the embodiment can be applied to prevention of novel coronavirus.
In the composition, garlic has a stable antibacterial effect, and the unpleasant odor generated by the garlic is the sulfide component in the garlic, and the component is in an orthorhombic molecular crystalline state, can block the synthesis and mutation of coronary pathogenic organisms from rapidly invading respiratory tract and inhibiting the growth of the coronary pathogenic organisms, and has very good effects of killing and inhibiting various bacteria and viruses and improving the immunity of organisms. Can also be used for preventing common cold, preventing wound infection, and treating infectious diseases. The dried orange peel has the effects of regulating qi, lowering adverse qi, regulating the middle warmer, stimulating appetite, eliminating dampness and phlegm, and has remarkable effect on inhibiting novel coronavirus due to synergistic effect of the two. The two components act synergistically and can form an oral protein microbial flora beneficial to human bodies in the oral cavity, thereby changing the properties of the novel coronavirus.
Meanwhile, garlic contains a capsaicin component called 'propylene sulfide', can reduce the content of bad cholesterol-low density lipoprotein in vivo, has the functions of obviously reducing blood fat, preventing thrombosis, promoting blood circulation and preventing coronary heart disease, arteriosclerotic heart disease and stroke, and can balance the sequelae of the new crown pneumonia after healing.
Example 2
This example provides a Chinese medicinal composition, which comprises 10g of fresh garlic and 10g of dried orange peel, wherein 10g of dried orange peel is soaked in 500ml of brown sugar water.
The preparation method of the composition comprises the following steps:
s1, peeling fresh garlic, grinding and crushing;
s2, soaking pericarpium Citri Reticulatae in brown sugar water to obtain pericarpium Citri Reticulatae water.
The composition is administered by chewing pulverized fresh garlic slowly to the pharynx, and then administering dried orange peel water.
The traditional Chinese medicine composition provided by the embodiment can be applied to prevention of novel coronavirus.
In the traditional Chinese medicine composition provided by the embodiment, the tangerine peel water is prepared by soaking tangerine peel in brown sugar water, wherein the brown sugar has high absorption and utilization rate, and also has the effects of conditioning breath and improving hypotension, and the tangerine peel water has synergistic effect with garlic and can obviously prevent novel coronavirus.
Example 3
The embodiment provides a traditional Chinese medicine composition, which comprises 7g of fresh garlic, 8g of dried orange peel and dried orange peel which are soaked in 200g of honey water.
The preparation method of the composition comprises the following steps:
s1, peeling fresh garlic, and cutting into powder;
s2, soaking pericarpium Citri Reticulatae in Mel water to obtain pericarpium Citri Reticulatae water.
The composition is administered by chewing pulverized fresh garlic slowly to the pharynx, and then administering dried orange peel water.
The traditional Chinese medicine composition provided by the embodiment can be applied to prevention of novel coronavirus.
Alternatively, the preparation method can also comprise extracting pulverized fresh Bulbus Allii and pericarpium Citri Tangerinae with water, concentrating, and making into pill.
In the traditional Chinese medicine composition provided by the embodiment, honey has the effects of moistening lung and reducing internal heat, and the crystal structure of honey can be cooperated with the crystal structure of garlic to destroy the RNA chain of the novel coronavirus.
Example 4
This example provides a Chinese medicinal composition comprising 6g of fresh garlic, 7g of dried orange peel, and dried orange peel soaked in 250g of rock candy water.
The preparation method of the composition comprises the following steps:
s1, peeling fresh garlic, cutting into pieces and crushing;
s2, soaking pericarpium Citri Reticulatae in crystal sugar water to obtain pericarpium Citri Reticulatae water.
The composition is administered by chewing pulverized fresh Bulbus Allii slowly to swallow, and then administering pericarpium Citri Tangerinae solution.
In the traditional Chinese medicine composition provided by the embodiment, the crystal sugar has the effects of tonifying middle-jiao and Qi, harmonizing stomach and moistening lung, and the crystal structure of the crystal sugar can be synergistic with that of garlic, so that the crystal sugar can destroy the RNA chain of the novel coronavirus.
Example 5
The embodiment provides a traditional Chinese medicine composition, which comprises 9g of fresh garlic, 6g of dried orange peel and dried orange peel soaked in 300g of brown sugar water.
Also comprises 30g of cassia bark, 30g of astragalus root, 30g of medlar, 30g of ginger, 30 parts of codonopsis pilosula and 10g of liquorice.
The traditional Chinese medicine composition is prepared by the following steps:
s1, peeling fresh garlic, and cutting into powder;
s2, soaking pericarpium Citri Reticulatae in crystal sugar water to obtain pericarpium Citri Reticulatae water.
S3, weighing the cassia bark, the astragalus root, the medlar, the ginger, the codonopsis pilosula and the liquorice according to the weight, and adding water to decoct the cassia bark, the astragalus root, the medlar, the ginger, the codonopsis pilosula and the liquorice into decoction.
The Chinese medicinal composition is taken in the following way: slowly chewing pulverized fresh Bulbus Allii, and administering pericarpium Citri Tangerinae water and the decoction.
Preferably, the decoction is prepared by decocting cortex Cinnamomi Japonici, radix astragali, fructus Lycii, rhizoma Zingiberis recens, radix Codonopsis, Glycyrrhrizae radix and native chicken.
The traditional Chinese medicine composition provided by the embodiment can be applied to prevention of novel coronavirus and can also be applied to health-care products.
Example 6
This example provides a Chinese medicinal composition, which comprises 6.5g of fresh garlic, 7.5g of dried orange peel, and dried orange peel soaked in 280g of honey water.
Also comprises 10g of gypsum, 10g of borneol and 10g of honeysuckle.
The traditional Chinese medicine composition is prepared by the following steps:
s1, peeling fresh garlic, and cutting into powder;
s2, soaking pericarpium Citri Reticulatae in Mel water to obtain pericarpium Citri Reticulatae water.
S3, weighing the gypsum, the borneol and the honeysuckle according to the weight, and adding water to decoct the mixture into a decoction.
The Chinese medicinal composition is taken in the following way: slowly chewing pulverized fresh Bulbus Allii, and administering pericarpium Citri Tangerinae water and the decoction.
The traditional Chinese medicine composition provided by the embodiment can be applied to prevention of novel coronavirus and can also be applied to health-care products.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the spirit or scope of the invention.
Claims (8)
1. A traditional Chinese medicine composition is characterized by comprising 5-10 parts by weight of fresh garlic and 5-10 parts by weight of dried orange peel, wherein the dried orange peel is soaked in 500 parts by weight of liquid of 100 portions.
2. The composition of claim 1, wherein the liquid is one of water, crystal sugar water, brown sugar water, or honey water.
3. The traditional Chinese medicine composition according to claim 2, further comprising 30 parts of cinnamon, 30 parts of radix astragali, 30 parts of medlar, 30 parts of ginger, 30 parts of radix codonopsis and 10 parts of liquorice by weight.
4. The traditional Chinese medicine composition according to claim 2, wherein the composition further comprises 10 parts by weight of gypsum, 10 parts by weight of borneol and 10 parts by weight of honeysuckle.
5. A method of preparing the Chinese medicinal composition of any one of claims 1-4, comprising the steps of:
peeling and crushing the fresh garlic;
and (3) soaking the dried orange peel in a solution, namely a dried orange peel solution.
6. The method for preparing a Chinese medicinal composition according to claim 5, further comprising the steps of extracting the pulverized garlic in a dried orange peel solution, concentrating, and preparing pills or granules.
7. The method for preparing a Chinese medicinal composition according to claim 5, wherein the fresh garlic is pulverized by crushing or chopping.
8. Use of a Chinese medicinal composition as claimed in any one of claims 1 to 4 for the prevention of a novel coronavirus infection.
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Application publication date: 20220610 |