CN114573692B - 用于检测嗜铬粒蛋白a的免疫测定与抗体 - Google Patents

用于检测嗜铬粒蛋白a的免疫测定与抗体 Download PDF

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CN114573692B
CN114573692B CN202210181051.3A CN202210181051A CN114573692B CN 114573692 B CN114573692 B CN 114573692B CN 202210181051 A CN202210181051 A CN 202210181051A CN 114573692 B CN114573692 B CN 114573692B
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chromogranin
antibody
antibodies
specific
cell line
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CN114573692A (zh
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帕斯卡利娜·卡吕埃尔
瓦莱丽·里戈
纳迪娜·介朗
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Cezanne SAS
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Cezanne SAS
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/042Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/044Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/062Gastritis or peptic ulcer disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/12Pulmonary diseases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/32Cardiovascular disorders
    • G01N2800/321Arterial hypertension

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN202210181051.3A 2014-04-15 2015-04-14 用于检测嗜铬粒蛋白a的免疫测定与抗体 Active CN114573692B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210181051.3A CN114573692B (zh) 2014-04-15 2015-04-14 用于检测嗜铬粒蛋白a的免疫测定与抗体

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14164809 2014-04-15
EP14164809.7 2014-04-15
CN201580019631.0A CN106461673A (zh) 2014-04-15 2015-04-14 用于检测嗜铬粒蛋白a的免疫测定与抗体
PCT/EP2015/058045 WO2015158701A1 (fr) 2014-04-15 2015-04-14 Dosage immunologique et anticorps pour la détection de la chromogranine a
CN202210181051.3A CN114573692B (zh) 2014-04-15 2015-04-14 用于检测嗜铬粒蛋白a的免疫测定与抗体

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CN114573692B true CN114573692B (zh) 2024-05-28

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CN201580019631.0A Pending CN106461673A (zh) 2014-04-15 2015-04-14 用于检测嗜铬粒蛋白a的免疫测定与抗体

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US (2) US10648984B2 (fr)
EP (2) EP3633378A1 (fr)
JP (2) JP6591442B2 (fr)
CN (2) CN114573692B (fr)
BR (1) BR112016021714A2 (fr)
DK (1) DK3132268T3 (fr)
EA (1) EA034364B1 (fr)
ES (1) ES2764225T3 (fr)
WO (1) WO2015158701A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112018067990A2 (pt) 2016-03-09 2019-02-05 Cezanne S A S cromogranina a como um marcador para câncer de bexiga
CN107090439B (zh) * 2017-06-02 2020-05-05 福州迈新生物技术开发有限公司 一株分泌抗嗜铬素a单克隆抗体的杂交瘤细胞株及其应用
WO2019178562A1 (fr) * 2018-03-16 2019-09-19 Quest Diagnostics Investments Llc Procédés de détection de chromogranine a par spectrométrie de masse
CN109507432A (zh) * 2018-11-14 2019-03-22 嘉兴行健生物科技有限公司 一种嗜铬蛋白a检测试剂及检测参考区间及检测方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632624B1 (en) * 1998-05-14 2003-10-14 Cis Bio International Human chromogranin A (CgA) immunologic assay, antibodies, reagents and kits for said assay
CN102520195A (zh) * 2011-12-30 2012-06-27 天津市协和医药科技集团有限公司 一种嗜铬粒蛋白a化学发光免疫分析试剂盒及其制备方法
CN102869681A (zh) * 2010-04-28 2013-01-09 欧罗诊断股份公司 嗜铬粒蛋白a的免疫测定法、抗体和试剂盒

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US4758522A (en) * 1985-03-08 1988-07-19 The Regents Of The University Of California Immunoassay for human chromogranin A
US6238877B1 (en) 1997-11-05 2001-05-29 Arup Institute Method for prediction prostate cancer patients' resistance to hormonal treatment by measuring serum concentrations of chromogranin A
US20050186642A1 (en) * 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
CN101377513A (zh) * 2008-04-16 2009-03-04 北京科美东雅生物技术有限公司 嗜铬素a化学发光免疫分析定量测定试剂盒及其制备方法
CN102482343A (zh) * 2009-06-16 2012-05-30 B.R.A.H.M.S有限公司 过氧化物氧还蛋白4的诊断应用
US9671413B2 (en) 2010-11-12 2017-06-06 William Marsh Rice University Prostate cancer point of care diagnostics
JP5817838B2 (ja) * 2011-11-02 2015-11-18 ウシオ電機株式会社 蛍光標識抗体可変領域含有ポリペプチド複合体を用いた蛍光免疫測定方法
US8658166B2 (en) 2011-11-08 2014-02-25 Caldera Health Limited Methods and materials for the diagnosis of prostate cancers
US8632971B2 (en) 2011-11-08 2014-01-21 Caldera Health Limited Methods and materials for determining the efficacy of prostate cancer therapies
BR112018067990A2 (pt) * 2016-03-09 2019-02-05 Cezanne S A S cromogranina a como um marcador para câncer de bexiga

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632624B1 (en) * 1998-05-14 2003-10-14 Cis Bio International Human chromogranin A (CgA) immunologic assay, antibodies, reagents and kits for said assay
CN102869681A (zh) * 2010-04-28 2013-01-09 欧罗诊断股份公司 嗜铬粒蛋白a的免疫测定法、抗体和试剂盒
CN102520195A (zh) * 2011-12-30 2012-06-27 天津市协和医药科技集团有限公司 一种嗜铬粒蛋白a化学发光免疫分析试剂盒及其制备方法

Non-Patent Citations (2)

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Cell-specific Processing of Chromogranin A in Endocrine Cells of the Rat Stomach;Per Norlen等;The Journal of Histochemistry & Cytochemistry;第49卷(第1期);9-18 *
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EP3132268A1 (fr) 2017-02-22
US11719697B2 (en) 2023-08-08
US20170122945A1 (en) 2017-05-04
JP6812521B2 (ja) 2021-01-13
CN106461673A (zh) 2017-02-22
JP2017514128A (ja) 2017-06-01
CN114573692A (zh) 2022-06-03
EA201692071A1 (ru) 2017-04-28
EA034364B1 (ru) 2020-01-30
US20200348304A1 (en) 2020-11-05
WO2015158701A1 (fr) 2015-10-22
BR112016021714A2 (pt) 2017-10-17
EP3633378A1 (fr) 2020-04-08
JP6591442B2 (ja) 2019-10-16
EP3132268B1 (fr) 2019-10-16
DK3132268T3 (da) 2020-01-02
US10648984B2 (en) 2020-05-12
ES2764225T3 (es) 2020-06-02
JP2020016660A (ja) 2020-01-30

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