CN114569677A - Traditional Chinese medicine formula for treating depression - Google Patents

Traditional Chinese medicine formula for treating depression Download PDF

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Publication number
CN114569677A
CN114569677A CN202210269117.4A CN202210269117A CN114569677A CN 114569677 A CN114569677 A CN 114569677A CN 202210269117 A CN202210269117 A CN 202210269117A CN 114569677 A CN114569677 A CN 114569677A
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chinese medicine
traditional chinese
medicine formula
treating depression
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任振芳
徐剑峰
崔赪
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Cui Cheng
Ren Zhenfang
Xu Xianfeng
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Shenzhen Zhongchang Health Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses a traditional Chinese medicine formula for treating depression, which comprises the following components in parts by weight: 18-22 parts of poria cocos, 14-16 parts of radix puerariae, 8-10 parts of rhizoma gastrodiae, 10-12 parts of dogwood, 10-12 parts of angelica sinensis, 3-4 parts of ginseng, 8-10 parts of rhizoma polygonati, 8-10 parts of liquorice and 10-12 parts of astragalus membranaceus. Is suitable for patients with depression of different sexes and age groups, and is mainly used for treating mild and moderate depression and climacteric syndrome.

Description

Traditional Chinese medicine formula for treating depression
Technical Field
The invention relates to the field of disease treatment, in particular to a traditional Chinese medicine formula for treating depression.
Background
Depression is a common mental disorder, and belongs to the category of depression in traditional Chinese medicine. The depression seriously troubles the life and work of patients and brings a heavy burden to families. Current treatments are mainly psychotherapeutic, pharmacotherapeutic and electroconvulsive (tic) therapy. The psychological treatment method is only suitable for mild cases, moderate and severe cases need drug treatment, and for severe cases, the method of electric shock treatment is used. Western medicines are mostly used as antidepressant medicines and have strong dependence.
The following were used: 1. tricyclic drugs: such as doxepin, amitriptyline, clomipramine and the like, although the medicaments have low price, the side effects are large, mainly dry mouth, accelerated heart rate and the like, and the life risk is caused by overdose of the medicaments.
2. 5-hydroxytryptamine reuptake blocking class: such as fluoxetine, paloxetine, sertraline and the like, can cause adverse gastrointestinal reactions such as constipation, nausea, vomiting and the like.
Norepinephrine drugs: mirtazapine, venlafaxine, etc. can produce side effects such as hepatotoxicity, sexual dysfunction, obesity, etc. when taken in excess.
Therefore, a traditional Chinese medicine formula for treating depression is provided.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine formula for treating depression.
In order to achieve the purpose, the invention is realized by the following technical scheme:
the invention provides a traditional Chinese medicine formula for treating depression, which comprises the following components in parts by weight: 18-22 parts of poria cocos, 14-16 parts of kudzu root, 8-10 parts of gastrodia elata, 10-12 parts of dogwood, 10-12 parts of angelica sinensis, 3-4 parts of ginseng, 8-10 parts of rhizoma polygonati, 8-10 parts of liquorice and 10-12 parts of astragalus membranaceus.
Preferably, the traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 18 parts of tuckahoe, 14 parts of kudzu root, 8 parts of gastrodia elata, 10 parts of dogwood, 10 parts of angelica, 3 parts of ginseng, 8 parts of rhizoma polygonati, 8 parts of liquorice and 10 parts of astragalus membranaceus.
Preferably, the traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 20 parts of tuckahoe, 15 parts of kudzu root, 9 parts of gastrodia elata, 11 parts of dogwood, 11 parts of angelica, 3 parts of ginseng, 9 parts of rhizoma polygonati, 9 parts of liquorice and 11 parts of astragalus membranaceus.
Preferably, the traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 22 parts of tuckahoe, 16 parts of kudzu root, 10 parts of gastrodia elata, 12 parts of dogwood, 12 parts of angelica, 4 parts of ginseng, 10 parts of rhizoma polygonati, 10 parts of liquorice and 12 parts of astragalus membranaceus.
Preferably, the traditional Chinese medicine needs 100 parts by weight of water, and is stewed in boiling water.
Preferably, the boiling water is stewed in a standard atmospheric pressure device for 3 hours.
Kudzu root: sweet and pungent in flavor and cool in nature; entering lung and stomach meridians; has effects in expelling pathogenic factors from muscles, relieving fever, promoting eruption, promoting salivation, quenching thirst, invigorating yang, and relieving diarrhea; can be used for treating fever due to exterior syndrome, pain of neck and back, measles without adequate eruption, fever thirst, yin deficiency with thirst, heat diarrhea, dysentery, and diarrhea due to spleen deficiency.
Gastrodia elata: mild in nature and bland in taste, entering liver meridian. Has effects of suppressing hyperactive liver, calming endogenous wind, and relieving spasm, and can be used for treating headache, giddiness, limbs anesthesia, infantile convulsion, epilepsia, convulsion, and tetanus. The rhizoma Gastrodiae extract and water decoction have tranquilizing, analgesic, and anticonvulsive effects; the rhizoma Gastrodiae polysaccharide has effects of enhancing nonspecific immunity and cellular immunity of experimental animal organism and resisting inflammation. In addition, it has the functions of delaying senility, inhibiting platelet aggregation, protecting cardiac muscle cell, etc.
Dogwood fruit: slightly warm in nature, sour and astringent in taste; entering liver and kidney meridians; has effects in tonifying liver and kidney, and inducing astringency to arrest spontaneous perspiration; can be used for treating vertigo, tinnitus, soreness of waist and knees, sexual impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, leukorrhagia, sweating, internal heat, and diabetes. Pharmacological research shows that the medicine has the functions of enhancing the immune system, resisting inflammation, resisting hemorrhagic shock, reducing blood sugar, inhibiting platelet aggregation, improving the cardiac function and the hemodynamics, resisting bacteria, promoting urination, etc.
Chinese angelica root: warm in nature, sweet and pungent in flavor; it enters liver meridian, heart meridian and spleen meridian; has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, loosening bowel, and relieving constipation; it is used to treat sallow complexion due to blood deficiency, vertigo, palpitation, menoxenia, amenorrhea, dysmenorrhea, abdominal pain due to deficiency cold, constipation due to intestinal dryness, rheumatic arthralgia, traumatic injury, carbuncle, cellulitis, and pyocutaneous disease.
Ginseng: warm in nature, sweet and slightly bitter in taste; enter heart meridian, lung meridian, spleen meridian, kidney meridian; has effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, and tranquilizing; can be used for treating asthenia, desire for loss of life, short breath, dyspnea, spontaneous perspiration, cold limbs, listlessness, anorexia, emesis, diarrhea, asthma due to qi deficiency, chronic cough, body fluid deficiency, thirst, diabetes, insomnia, dreaminess, palpitation, amnesia, sexual impotence, frequent micturition, and deficiency of qi, blood, and body fluid. Ginseng radix has effects of bidirectional regulating central nervous system, promoting intelligence, relieving pain, relieving fever, resisting convulsion and reducing muscle strength. Has effects in tonifying heart, relieving ischemia, dilating blood vessel, and lowering blood pressure; has the functions of protecting and stimulating hematopoiesis to the blood system, and resisting blood coagulation and thrombus; has corticotropin-like and sex hormone-like effects on endocrine system.
Rhizoma polygonati: mild in nature and sweet in taste; it enters lung, spleen and kidney meridians; has effects in invigorating qi, nourishing yin, invigorating spleen, moistening lung, and invigorating kidney; it is used to treat weakness of spleen and stomach, tiredness, asthenia, xerostomia, dry cough due to lung deficiency, insufficiency of essence and blood, and diabetes due to internal heat.
Licorice root: mild in nature and sweet in taste; the heart meridian, the stomach meridian, the spleen meridian and the lung meridian; has effects in invigorating spleen, invigorating qi, relieving cough, eliminating phlegm, relieving spasm, relieving pain, and regulating drug properties; treating weakness of spleen and stomach, deficiency of middle-warmer energy, cough, asthma, carbuncle, sore, abdominal spasm, pain, and relieving drug toxicity. Unprocessed for clearing heat, stir-baked for tonifying middle energizer.
Astragalus root: mild in nature and sweet in taste; spleen and lung meridians entered; has effects in invigorating qi, consolidating superficial resistance, promoting urination, expelling toxin, expelling pus, and promoting granulation; can be used for treating short breath, palpitation, asthenia, collapse, spontaneous perspiration, night sweat, asthenia, edema, chronic nephritis, chronic diarrhea, proctoptosis, uterine prolapse, carbuncle, cellulitis, ulcer, infantile bronchial asthma, chronic hepatitis B, chronic nephritis, and viral myocarditis. Stir-baked for tonifying qi, unprocessed for checking sweating, inducing diuresis, expelling toxin, discharging pus and promoting tissue regeneration.
The invention has the following beneficial effects:
the traditional Chinese medicine composition has the advantages of simple raw materials, low cost, quick curative effect, simple and convenient use, improvement of the curative effect and no toxic or side effect by adopting a specific traditional Chinese medicine extraction method compared with other compositions for treating depression. Is suitable for patients with depression of different sexes and age groups, and is mainly used for treating mild and moderate depression and climacteric syndrome.
Detailed Description
The following further describes embodiments of the present invention with reference to examples. The following examples are only for illustrating the technical solutions of the present invention more clearly, and the protection scope of the present invention is not limited thereby.
Example 1
The traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 18 parts of tuckahoe, 14 parts of kudzu root, 8 parts of gastrodia elata, 10 parts of dogwood, 10 parts of angelica, 3 parts of ginseng, 8 parts of rhizoma polygonati, 8 parts of liquorice and 10 parts of astragalus membranaceus.
The traditional Chinese medicine needs 100 parts by weight of water, and is stewed in boiling water.
Boiling water was used for 3 hours under standard atmospheric pressure.
Example 2
The traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 20 parts of poria cocos, 15 parts of kudzu root, 9 parts of gastrodia elata, 11 parts of dogwood, 11 parts of angelica sinensis, 3 parts of ginseng, 9 parts of rhizoma polygonati, 9 parts of liquorice and 11 parts of astragalus membranaceus.
The traditional Chinese medicine needs 100 parts by weight of water, and is stewed in boiling water.
Boiling water was used for 3 hours under standard atmospheric pressure.
Example 3
The traditional Chinese medicine formula for treating depression comprises the following components in parts by weight: 22 parts of tuckahoe, 16 parts of kudzu root, 10 parts of rhizoma gastrodiae, 12 parts of dogwood, 12 parts of angelica, 4 parts of ginseng, 10 parts of rhizoma polygonati, 10 parts of liquorice and 12 parts of astragalus.
The traditional Chinese medicine is prepared by mixing 100 parts by weight of water, and stewing in boiling water.
Boiling water was used for 3 hours under standard atmospheric pressure.
The invention researches the medical records as follows: in the first case, a woman is 42 years old today, sleep disorder is about ten years old, the woman can sleep after lying for about two hours, the woman does not sleep all night seriously, the brain is uncontrolled, and the woman feels reluctant to think about, after eating 3 courses of traditional Chinese medicine this year, the sleep quality is improved greatly, the mind is joyful, and the body is relaxed.
Case two: zhao, a woman, 32 years old, 3 months postpartum, the self-describing emotion is extremely low, the feeling of anxiety, sitting and standing is uneasy, the mind is indefinite, the people love the spleen qi, the thinking is slow, the people feel tired, the people can hardly fall asleep without taking hypnotics at night, diagnosis and treatment are carried out before introduction by friends, the emotion and sleep are greatly improved after three months of treatment, and the people recover to be normal after half a year.
Case three, Dongqi, male, age 31. Disease occurred in 11 months in 2008, and 12 years so far. At that time, the patient can not feel suffocated and sleep at night, the illusion and the auditory hallucinations appear, western medicines such as viscusia, olanzapine and the like are taken, although the sleep is increased, the illusion always exists, the body is fat, and the emotion is dull. The traditional Chinese medicine formula is taken from No. 4/8, all the functions of the body are recovered, and the patient can not have trouble.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (6)

1. The traditional Chinese medicine formula for treating depression is characterized by comprising the following components in parts by weight: 18-22 parts of poria cocos, 14-16 parts of radix puerariae, 8-10 parts of rhizoma gastrodiae, 10-12 parts of dogwood, 10-12 parts of angelica sinensis, 3-4 parts of ginseng, 8-10 parts of rhizoma polygonati, 8-10 parts of liquorice and 10-12 parts of astragalus membranaceus.
2. The traditional Chinese medicine formula for treating depression according to claim 1, which is characterized by comprising the following components in parts by weight: 18 parts of tuckahoe, 14 parts of kudzu root, 8 parts of gastrodia elata, 10 parts of dogwood, 10 parts of angelica, 3 parts of ginseng, 8 parts of rhizoma polygonati, 8 parts of liquorice and 10 parts of astragalus membranaceus.
3. The traditional Chinese medicine formula for treating depression according to claim 1, which is characterized by comprising the following components in parts by weight: 20 parts of poria cocos, 15 parts of kudzu root, 9 parts of gastrodia elata, 11 parts of dogwood, 11 parts of angelica sinensis, 3 parts of ginseng, 9 parts of rhizoma polygonati, 9 parts of liquorice and 11 parts of astragalus membranaceus.
4. The traditional Chinese medicine formula for treating depression according to claim 1, which is characterized by comprising the following components in parts by weight: 22 parts of tuckahoe, 16 parts of kudzu root, 10 parts of rhizoma gastrodiae, 12 parts of dogwood, 12 parts of angelica, 4 parts of ginseng, 10 parts of rhizoma polygonati, 10 parts of liquorice and 12 parts of astragalus.
5. The traditional Chinese medicine formula for treating depression according to claim 1, wherein the traditional Chinese medicine is prepared by mixing 100 parts by weight of water and stewing in boiling water.
6. The traditional Chinese medicine formula for treating depression according to claim 5, wherein the boiling water stewing is carried out under a standard atmospheric pressure for 3 hours.
CN202210269117.4A 2022-03-18 2022-03-18 Traditional Chinese medicine formula for treating depression Pending CN114569677A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450103A (en) * 2007-11-30 2009-06-10 戚郁芬 Medicine composition for treating hypochondria and anxiety neurosis
CN112826901A (en) * 2019-11-24 2021-05-25 王忠民 Medicine for quickly relieving senile dementia symptoms
CN113575944A (en) * 2021-06-29 2021-11-02 任振芳 Food additive with efficacy of expelling toxoplasma gondii and preparation method and application thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450103A (en) * 2007-11-30 2009-06-10 戚郁芬 Medicine composition for treating hypochondria and anxiety neurosis
CN112826901A (en) * 2019-11-24 2021-05-25 王忠民 Medicine for quickly relieving senile dementia symptoms
CN113575944A (en) * 2021-06-29 2021-11-02 任振芳 Food additive with efficacy of expelling toxoplasma gondii and preparation method and application thereof

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