CN104257883A - Traditional Chinese medicine composition for treating leucopenia after chemotherapy - Google Patents

Traditional Chinese medicine composition for treating leucopenia after chemotherapy Download PDF

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CN104257883A
CN104257883A CN201410559624.7A CN201410559624A CN104257883A CN 104257883 A CN104257883 A CN 104257883A CN 201410559624 A CN201410559624 A CN 201410559624A CN 104257883 A CN104257883 A CN 104257883A
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杨波
王海荣
王金绪
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杨波
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    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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Abstract

The invention discloses a traditional Chinese medicine composition for treating leucopenia after chemotherapy. The traditional Chinese medicine composition comprises the following raw materials: herba epimedii, radix morindae officinalis, astragalus membranaceus, herba pyrrosiae, caulis spatholobi, safflower, polygonum cuspidatum, polygonum multiflorum, raw white paeony root, fructus psoraleae, cortex lycii radicis, glossy privet fruit, cistanche, madder, stir-baked squama manitis and root of red-rooted salvia. The traditional Chinese medicine composition has the advantage of dialectical therapy of traditional Chinese medicine, is prepared by mixing the raw materials through multi-time clinical verifications, and has the effects of benefiting vital energy, nourishing blood, tonifying the spleen and kidney and regulating yin and yang of internal organs; after the traditional Chinese medicine composition is taken, the vital energy function of the body can be regulated, the blood can be replenished and activated, the kidney can be nourished, the essence can be strengthened, the marrow can be replenished, the yin and yang can be regulated, and the internal organs can be balanced, so that the immunity function can be improved and the survival and antiviral activity and the like of cell bodies can be enhanced; the hematopoietic system of a human body can be protected and the secretion of hematopoietic factors can be promoted, so that the blood biochemistry process is accelerated; the bone marrow microcirculation is improved, the bone marrow hyperplasia is stimulated, the nucleic acid synthesis of hematopoietic cells and the proliferation and differentiation of multipotential stem cells are promoted, and the leukocytopoiesis is stimulated, so that the clinical treatment standards are met.

Description

A kind of Chinese medicine composition for the treatment of leukopenia after chemotherapy
Technical field
The invention belongs to the field of Chinese medicines, specifically a kind of Chinese medicine composition can treating leukopenia after chemotherapy.
Background technology
Chemotherapy is one of Main Means for the treatment of tumor, and so its toxic and side effects is large, and common nausea,vomiting,diarrhea, alopecia, inappetence, tired weak, blood three are the diseases such as minimizing.Chemotherapeutics often lacks selectivity, while tumors destroyed cell, there is bone marrow depression, to the coup injury of hematopoietic stem cell and the damage to bone marrow mechanism cell or microcirculatory structure or function, cause leukopenia, cause the generation of the complication such as secondary infection, make chemotherapy be forced to interrupt, affect patient and effectively treat.Chemotherapy also can cause the damage of patient's body's immunity simultaneously.
Leukopenia refers to that patient peripheral's total white blood cells continues lower than 4 × 10 9/ L.At present, the leukopenia occurred after treatment chemotherapy, adopts the Western medicine therapies such as batilol, leucogen, granulocyte colony-stimulating factor, low dose of hormonotherapy clinically, although there is certain leukocyte increasing effect, but costly, be easy to repeatedly, curative effect is unreliable.Research shows, Chinese medicine leukocyte increasing has unique advantage, compensate for the deficiency of western medicine therapy.Traditional Chinese Medicine Fuzheng consolidates, attenuation synergistic; Stable curative effect, lasting; Improve body's immunity, transfer body resistance against diseases; Reduce chemotherapeutic to the injury of body, be conducive to completing smoothly of chemotherapy; Reduce the financial burden, shorten length of stay as far as possible; Extend life cycle, improve life quality.
Summary of the invention
The problem to be solved in the present invention is for above problem, the Chinese medicine composition for the treatment of leukopenia after chemotherapy provide a kind of strengthening the body resistance, stable curative effect, not easily recurring.
For solving the problem, the technical solution adopted in the present invention is:
Treat a Chinese medicine composition for leukopenia after chemotherapy, it is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20-30 gram, bar halberd 10-20 gram, Radix Astragali 10-20 gram, Folium Pyrrosiae 10-20 gram, Caulis Spatholobi 10-20 gram, Flos Carthami 10-20 gram, Rhizoma Polygoni Cuspidati 10-20 gram, Radix Polygoni Multiflori 10-20 gram, Radix Paeoniae Alba 10-20 gram, Fructus Psoraleae 8-15 gram, Cortex Lycii 8-12 gram, Fructus Ligustri Lucidi 8-12 gram, Herba Cistanches 8-12 gram, Radix Rubiae 8-12 gram, stir-baked SQUAMA MANITIS 8-12 gram, Radix Salviae Miltiorrhizae 8-15 gram.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20 grams, bar halberd 10 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 10 grams, Caulis Spatholobi 10 grams, Flos Carthami 10 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 10 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 8 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 8 grams, Herba Cistanches 8 grams, 8 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 8 grams, Radix Salviae Miltiorrhizae 8 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 30 grams, bar halberd 20 grams, the Radix Astragali 20 grams, Folium Pyrrosiae 20 grams, Caulis Spatholobi 20 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 20 grams, the Radix Polygoni Multiflori 20 grams, Radix Paeoniae Alba 20 grams, Fructus Psoraleae 15 grams, Cortex Lycii 12 grams, Fructus Ligustri Lucidi 12 grams, Herba Cistanches 12 grams, 12 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 15 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20 grams, bar halberd 20 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 10 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 15 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 12 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 8 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 25 grams, bar halberd 15 grams, the Radix Astragali 15 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 15 grams, Flos Carthami 15 grams, Rhizoma Polygoni Cuspidati 15 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 15 grams, Fructus Psoraleae 12 grams, Cortex Lycii 10 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 10 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 10 grams, Radix Salviae Miltiorrhizae 12 grams.
As a kind of prioritization scheme:
Described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Get 90 grams after Chinese medicine in described Chinese medicine composition mixes by weight, add water 800 milliliters, decoct to 500 milliliters, elimination medicinal residues, obtain oral administration solution.
Wherein:
Herba Epimedii, acrid, sweet, warm.Return liver, kidney channel.There is kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling.For muscles and bones Microsoft, rheumatic arthralgia, numbness contracture, climacteric hypertension.Herba Epimedii strengthens function of immune system in addition, the anabolic effect of blood pressure lowering, promotion medullary cell DNA.
Ba Ji, slightly warm in nature, sweet in the mouth, pungent.There is kidney-replenishing, benefiting essence-blood, effect of strengthening bone and muscle.Bar halberd can treat the muscles and bones Microsoft of deficiency of the liver and kindey, and lumbocrural pain, or rheumatism lingering arthralgia, walk with difficulty.
The Radix Astragali, sweet, tepor.Return lung, spleen, liver, kidney channel.Have benefiting QI for strengthening the superficies, arresting sweating takes off admittedly, holder skin ulcer granulation promoting, effect of inducing diuresis to remove edema.Be used for the treatment of the power of the deficiency of vital energy, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes.The Radix Astragali significantly can increase the total white blood cells in blood, promotes phagocytic function and the sterilizing ability of neutrophilic granulocyte and macrophage, obviously strengthens cellular immunization.The Radix Astragali also can protect the liver, resisting fatigue, heart tonifying, adjustment blood pressure, antiulcer, antitumor, osteoporosis.
Folium Pyrrosiae, cold nature, sweet in the mouth, hardship.Feeble QI, the micro-puckery hardship of taste.There is inducing diuresis for treating stranguria syndrome, effect of clearing away heat to stop bleeding.For pyretic stranguria, stranguria caused by urinary stone, dysuria, the puckery pain of pouring drop, haematemesis, epistaxis, hematuria, metrorrhagia, lung-heat, cough.
Caulis Spatholobi, bitter, sweet, temperature.Return liver, kidney channel.Enrich blood, invigorate blood circulation, effect of dredging collateral.For blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Caulis Spatholobi also has blood pressure lowering, anticancer effect.
Flos Carthami, acrid in the mouth, warm in nature, GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of stasis-dispelling and pain-killing.Cure mainly obstruction of qi in the chest and cardialgia, accumulation of blood, traumatic injury congestive edema, arthralgia, paralysis due to windstroke, macular eruption being dark-purple.Flos Carthami also has effect of blood pressure lowering, anticoagulation, resisting fatigue, analgesia, calmness, antiinflammatory.
Rhizoma Polygoni Cuspidati, micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, three pre-analgesic therapies, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, cough with copious phlegm, injury from falling down, carbuncle sore tumefacting virus.Rhizoma Polygoni Cuspidati has inhibitory action to various bacteria, virus and leptospira, also have antitussive in addition, relieving asthma, reduce phlegm, cathartic relieving constipation, protect the liver, antitumor, hemostasis effect.
The Radix Polygoni Multiflori, sweet, bitter, property is put down.GUIXIN, liver, large intestine channel.There is removing toxicity for eliminating carbuncles, effect of loosening bowel to relieve constipation.Be used for the treatment of rheumatism pruritus, dryness of the intestine constipation, the Radix Polygoni Multiflori also can promote hemopoietic function, strengthen immunologic function, blood fat reducing, atherosclerosis.
Radix Paeoniae Alba, bitter, sour, be slightly cold.Return liver, spleen channel.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, effect of astringing YIN to stop sweating.For dizzy, costalgia, stomachache, limb pain twin, blood deficiency and yellow complexion, spontaneous perspiration, the night sweat of having a headache.Radix Paeoniae Alba is scalable body immune system also, calm, analgesia, hepatoprotective, antiinflammatory, antibacterial and can the formation of anticoagulant and thrombosis.
Fructus Psoraleae, nature and flavor are pungent, bitter, temperature.Return kidney, spleen channel.There is reinforcing the kidney and supporting YANG, helping inspiration to relieve asthma, warming spleen and stopping diarrha effect.Main insufficiency of kidney-YANG, below element deficiency and cold, chills and pain of the waist and kness, frequent micturition, failure of the kidney in receiving QI, dyspnea due to deficiency is more than, asthenia of both the spleen and kidney, stool chronic diarrhea.Psoralen has stronger lethal effect to human leukemia cell, can significantly strengthen its immunologic function.
Cortex Lycii, cold in nature, sweet in the mouth.Enter lung, liver, kidney channel.Removing heat from blood is had to remove steaming, effect of lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, Lip river blood, epistaxis.
Fructus Ligustri Lucidi, sweet, bitter, cold.Return liver, kidney channel.Nourishing is had to stand up, effect of improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision, the hepatic and renal YIN deficiency, fever due to yin deficiency, gastropathy, gout and hyperuricemia.
Herba Cistanches, sweet, salty, temperature.Return kidney, large intestine channel.Kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.For soreness of the waist and knees, muscles and bones is unable, dryness of the intestine constipation.
Radix Rubiae, bitter, cold.Return Liver Channel.Removing heat from blood, hemostasis, blood stasis dispelling, stimulates the menstrual flow.For spitting blood, epistaxis, amenorrhea stasis blocking, arthralgia, tumbling and swelling.Radix Rubiae also can leukocyte increasing, anticancer, anti-infarction, antitussive, spasmolytic, adjustment metabolism, antibacterial.
Stir-baked SQUAMA MANITIS, has the routed carbuncle of detumescence, searches effect that wind is active.
Radix Salviae Miltiorrhizae, bitter, be slightly cold.GUIXIN, Liver Channel.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Chinese medicine " asthenia " category is belonged to according to differential diagnosis in tcm this disease theoretical.The spleen being the foundation of acquired constitution, source of generating QI and blood, as the congenital foundation, the raw marrow of main bone, spleen kidney deficiency, sends out the card for " asthenia ".Chemotherapy, as evil poison infringement body, causes internal organs QI and blood damage, especially impaired, the taste imbalance of kidney channel, neurally loses, and bone marrow does not fill, then essence and blood can not demutation; Deficiency-weakness of spleen-QI, indigestion, changes source not enough, and whole body loses supports, then deficient exhaustion all extremely.
The traditional Chinese medical science is thought, also, Chinese medicine composition of the present invention, with the advantage of tcm treatment according to syndrome differentiation, draws blood person foodstuff essence after several clinical verification compatibility, has effect that benefiting QI and nourishing blood, by force spleen are good for kidney, mediation internal organs negative and positive.After taking, drug effect in focus, rapid-onset, scalable body mechanism of qi, promoting the circulation of blood of enriching blood, the kidney invigorating and essence nourishing fills out marrow, YIN and YANG balance regulating, balance internal organs, thus strengthens immunologic function, extends cyton survival and antiviral isoreactivity; Protection human body hemopoietic system, improves the secretion of Hemopoietic factor, makes blood biochemical rapid; Improve Microcirculation in Bone Marrow, stimulate myelosis, promote the synthesis of hematopoietic cell nucleic acid and multipotency hepatocyte growth and differentiation, stimulation Leukocytopoiesis, thus reach clinical treatment standard.
In addition, Chinese medicine composition of the present invention not only good effect, and green natural, safe and reliable, not easily recur.Each course for the treatment of is seven days, takes the efficiency index that two to three courses for the treatment of can reach leukocyte increasing, and the leukopenia patient census after the routine chemotherapy of clinical treatment 98 shows, overall clinical efficacy rate reaches more than 93%.
Manufacture method of the present invention:
After being mixed by weight by above-mentioned Chinese medicine, add water 800 milliliters, decoct to 500 milliliters, filtering medicinal residues, obtain oral liquid.Be ground into end after above-mentioned Chinese medicine can mix by tablet, powder, pill or capsule by weight as made, make tablet, powder, pill or capsule.
Instructions of taking: every day potion, every day three times, bfore meals, within seven days, be a course for the treatment of.
For investigating clinical efficacy and the safety of Chinese medicine composition of the present invention further, we have selected the treatment curative effect of 98 routine leukopenia after chemotherapy patients to medicine of the present invention and carry out clinical trial.
Inclusive criteria:
1. all cases all through cytology or histopathologic diagnosis be malignant tumor;
2. there is chemotherapy indication;
3. without severe cardiac, Liver and kidney function obstacle and disease of hematopoietic system.4. reduce number through Leukocytes after Chemotherapy and meet inclusive criteria.
Exclusion standard:
1. because infecting, the leukopenia patient that causes of other factors such as immunity;
2. data is imperfect;
3. allergic constitution or multi-medicament allergy sufferers.
98 routine leukopenia after chemotherapy patients are divided into two groups at random, often organize 49 examples.In treatment group, man 26 example, female 23 example, 28 ~ 76 years old age, 46 years old mean age.In matched group, man 27 example, female 22 example, 26 ~ 75 years old age, 45 years old mean age.Two groups of there are no significant in age, sex, the course of disease and severity extent etc. differences (P>0.05), have comparability.
Therapeutic Method: all patients all give conventional Supporting Therapy of suiting the medicine to the illness.Treatment group takes Chinese medicine composition of the present invention, decocting extracting juice 500ml, every day 1 dose, and point morning, noon and afternoon 3 times are oral.The oral batilol 40mg of matched group, every day 3 times; Leucogen 20mg, every day 3 times; Adenine phosphate 20mg, every day 3 times.Two groups equal 7 days is 1 course for the treatment of, and 2 courses for the treatment of terminate rear equal follow-up observation 3 months, observe two groups of clinical efficacies.
Curative effect judging standard: according to leukocyte increasing criterion of therapeutical effect in " clinical drug research guideline " that health ministry is worked out.
1. effective: total white blood cells>=4 × 10 9/ L, and maintain curative effect until drug withdrawal 1 month, clinical symptoms significantly weakens or disappears;
2. effective: total white blood cells 4.0 × 10 9/ L, but rise 0.5 ~ 1.0 × 10 than before treatment 9/ L, and can curative effect be maintained until drug withdrawal 1 month, clinical symptoms takes a turn for the better;
3. invalid: total white blood cells increases 0.5 × 10 9/ L, clinical symptoms is without improvement.
Curative effect comparision result after two groups of case treatments is as table one.
Table 1 liang group comparitive study table
Group Number of cases Effective n (%) Effective n (%) Invalid n (%) Total effective rate n (%)
Treatment group 49 32(65.31) 14(28.57) 3(6.12) 46(93.88)
Matched group 49 15(30.61) 23(46.94) 11(22.45) 38(77.55)
Conclusion: treatment group total effective rate 93.88%, matched group total effective rate 77.55%, two groups of comparing differences have statistical significance (P<0.05).By contrast, obviously find out that treatment group leukocyte increasing curative effect is obviously better than matched group.Compare with Western medicine, Chinese medicine composition of the present invention is not only effective, and also has effect steadily lasting, low price, safe and reliable advantage, can improve clinical symptoms preferably, improve the quality of life of tumor patient promoting leukocytic while.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition being used for the treatment of leukopenia after chemotherapy, choose Herba Epimedii 20 grams, bar halberd 10 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 10 grams, Caulis Spatholobi 10 grams, Flos Carthami 10 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 10 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 8 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 8 grams, Herba Cistanches 8 grams, 8 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 8 grams, Radix Salviae Miltiorrhizae 8 grams, get 90 grams after mixing and add water 800 milliliters, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.
Embodiment 2: a kind of Chinese medicine composition being used for the treatment of leukopenia after chemotherapy, choose Herba Epimedii 30 grams, bar halberd 20 grams, the Radix Astragali 20 grams, Folium Pyrrosiae 20 grams, Caulis Spatholobi 20 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 20 grams, the Radix Polygoni Multiflori 20 grams, Radix Paeoniae Alba 20 grams, Fructus Psoraleae 15 grams, Cortex Lycii 12 grams, Fructus Ligustri Lucidi 12 grams, Herba Cistanches 12 grams, 12 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 15 grams, get 90 grams after mixing and add water 800 milliliters, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.
Embodiment 3: a kind of Chinese medicine composition being used for the treatment of leukopenia after chemotherapy, choose Herba Epimedii 20 grams, bar halberd 20 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 10 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 15 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 12 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 8 grams, get 90 grams after mixing and add water 800 milliliters, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.
Embodiment 4: a kind of Chinese medicine composition being used for the treatment of leukopenia after chemotherapy, choose Herba Epimedii 25 grams, bar halberd 15 grams, the Radix Astragali 15 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 15 grams, Flos Carthami 15 grams, Rhizoma Polygoni Cuspidati 15 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 15 grams, Fructus Psoraleae 12 grams, Cortex Lycii 10 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 10 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 10 grams, Radix Salviae Miltiorrhizae 12 grams, get 90 grams after mixing and add water 800 milliliters, decoct to 500 milliliters, every day potion, every day three times, each 160 milliliters, bfore meals, within seven days, be a course for the treatment of.
Some patients healing case is as follows:
Side certain, women, 39 years old, patient did gastric operation the year before because of gastric cancer, accepted chemotherapy afterwards, and Leukocytes after Chemotherapy is extremely low, used and rose the chemotherapy of carrying out next course for the treatment of after leukocyte is risen to certain level by BAIYAO again.But along with the progress of chemotherapy, leukocyte starts again to decline.From taking a course for the treatment of of Chinese medicine composition of the present invention, leukocyte just rises to 3000/ microlitre from 2000/ microlitre, so start the chemotherapy of next course for the treatment of, chemotherapeutic period still adheres to using Chinese medicine composition of the present invention, and within after end of chemotherapy second day, have a blood test, leukocyte is 4300/ microlitre, patient mental is in good condition, have a meal comparatively and be improved greatly, leukocyte rises to more than 5000/ microlitre, and maintains in this level always.
In certain, female, 75 years old, patient has rectal cancer, Leukocytes after Chemotherapy reduces, and coordinates western modern medicine treatment, though leukocyte count raises to some extent, but effect repeatedly, go hospital assay, leukocyte does not reach criterion of acceptability always, takes three courses for the treatment of of Chinese medicine composition of the present invention, leukocyte count is elevated to criterion of acceptability, follows up a case by regular visits to and maintains normal level in three months always.
Hao, man, 59 years old, patient suffered from pulmonary carcinoma, and after chemotherapy, appetite obviously declines, and quantity of leucocyte reduces.Fail to reach criterion of acceptability, take two courses for the treatment of of Chinese medicine composition of the present invention, appetite improves, and leukocyte rises to criterion of acceptability.
Zheng, man, 68 years old, pulmonary carcinoma mid-term, post-surgical chemotherapy, Leukocytes after Chemotherapy just drops to from 2000/ microlitre to 3000/ microlitre, take three courses for the treatment of of Chinese medicine composition of the present invention, leukocyte count was elevated to criterion of acceptability.Follow up a case by regular visits to and maintain normal level in three months always.

Claims (5)

1. treat a Chinese medicine composition for leukopenia after chemotherapy, it is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20-30 gram, bar halberd 10-20 gram, Radix Astragali 10-20 gram, Folium Pyrrosiae 10-20 gram, Caulis Spatholobi 10-20 gram, Flos Carthami 10-20 gram, Rhizoma Polygoni Cuspidati 10-20 gram, Radix Polygoni Multiflori 10-20 gram, Radix Paeoniae Alba 10-20 gram, Fructus Psoraleae 8-15 gram, Cortex Lycii 8-12 gram, Fructus Ligustri Lucidi 8-12 gram, Herba Cistanches 8-12 gram, Radix Rubiae 8-12 gram, stir-baked SQUAMA MANITIS 8-12 gram, Radix Salviae Miltiorrhizae 8-15 gram.
2. the Chinese medicine composition for the treatment of leukopenia after chemotherapy according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20 grams, bar halberd 10 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 10 grams, Caulis Spatholobi 10 grams, Flos Carthami 10 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 10 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 8 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 8 grams, Herba Cistanches 8 grams, 8 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 8 grams, Radix Salviae Miltiorrhizae 8 grams.
3. the Chinese medicine composition for the treatment of leukopenia after chemotherapy according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 30 grams, bar halberd 20 grams, the Radix Astragali 20 grams, Folium Pyrrosiae 20 grams, Caulis Spatholobi 20 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 20 grams, the Radix Polygoni Multiflori 20 grams, Radix Paeoniae Alba 20 grams, Fructus Psoraleae 15 grams, Cortex Lycii 12 grams, Fructus Ligustri Lucidi 12 grams, Herba Cistanches 12 grams, 12 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 15 grams.
4. the Chinese medicine composition for the treatment of leukopenia after chemotherapy according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 20 grams, bar halberd 20 grams, the Radix Astragali 10 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 10 grams, Flos Carthami 20 grams, Rhizoma Polygoni Cuspidati 10 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 10 grams, Fructus Psoraleae 15 grams, Cortex Lycii 8 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 12 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 12 grams, Radix Salviae Miltiorrhizae 8 grams.
5. the Chinese medicine composition for the treatment of leukopenia after chemotherapy according to claim 1, is characterized in that, described Chinese medicine composition is made up of the Chinese herb of following weight portion:
Herba Epimedii 25 grams, bar halberd 15 grams, the Radix Astragali 15 grams, Folium Pyrrosiae 15 grams, Caulis Spatholobi 15 grams, Flos Carthami 15 grams, Rhizoma Polygoni Cuspidati 15 grams, the Radix Polygoni Multiflori 15 grams, Radix Paeoniae Alba 15 grams, Fructus Psoraleae 12 grams, Cortex Lycii 10 grams, Fructus Ligustri Lucidi 10 grams, Herba Cistanches 10 grams, 10 grams, Radix Rubiae, stir-baked SQUAMA MANITIS 10 grams, Radix Salviae Miltiorrhizae 12 grams.
CN201410559624.7A 2014-10-20 2014-10-20 Traditional Chinese medicine composition for treating leucopenia after chemotherapy Pending CN104257883A (en)

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CN104800404A (en) * 2015-04-23 2015-07-29 郑奎英 Traditional Chinese medicine preparation for treating leucopenia after chemotherapy
CN105412900A (en) * 2016-01-21 2016-03-23 于曰俊 Traditional Chinese medicine preparation for treating syndromes after interventional operation
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CN104800404A (en) * 2015-04-23 2015-07-29 郑奎英 Traditional Chinese medicine preparation for treating leucopenia after chemotherapy
CN105412900A (en) * 2016-01-21 2016-03-23 于曰俊 Traditional Chinese medicine preparation for treating syndromes after interventional operation
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