CN114431328A - Composite tablet candy capable of improving symptoms of female dysmenorrhea - Google Patents
Composite tablet candy capable of improving symptoms of female dysmenorrhea Download PDFInfo
- Publication number
- CN114431328A CN114431328A CN202210128273.9A CN202210128273A CN114431328A CN 114431328 A CN114431328 A CN 114431328A CN 202210128273 A CN202210128273 A CN 202210128273A CN 114431328 A CN114431328 A CN 114431328A
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- Prior art keywords
- powder
- compound
- parts
- candy
- turmeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 43
- 206010013935 Dysmenorrhoea Diseases 0.000 title claims abstract description 24
- 208000005171 Dysmenorrhea Diseases 0.000 title claims abstract description 22
- 208000024891 symptom Diseases 0.000 title claims abstract description 21
- 239000002131 composite material Substances 0.000 title claims abstract description 17
- 239000000843 powder Substances 0.000 claims abstract description 49
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 24
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract description 23
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 22
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims abstract description 21
- 235000013793 astaxanthin Nutrition 0.000 claims abstract description 21
- 239000001168 astaxanthin Substances 0.000 claims abstract description 21
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims abstract description 21
- 229940022405 astaxanthin Drugs 0.000 claims abstract description 21
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 20
- 235000003373 curcuma longa Nutrition 0.000 claims abstract description 20
- 235000013976 turmeric Nutrition 0.000 claims abstract description 20
- 240000000851 Vaccinium corymbosum Species 0.000 claims abstract description 17
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims abstract description 17
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims abstract description 17
- 235000021014 blueberries Nutrition 0.000 claims abstract description 17
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims abstract description 14
- 235000017803 cinnamon Nutrition 0.000 claims abstract description 14
- 108010010803 Gelatin Proteins 0.000 claims abstract description 13
- 229920000159 gelatin Polymers 0.000 claims abstract description 13
- 239000008273 gelatin Substances 0.000 claims abstract description 13
- 235000019322 gelatine Nutrition 0.000 claims abstract description 13
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 13
- 235000000346 sugar Nutrition 0.000 claims abstract description 12
- 150000005846 sugar alcohols Chemical class 0.000 claims abstract description 12
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 11
- 235000013336 milk Nutrition 0.000 claims abstract description 10
- 239000008267 milk Substances 0.000 claims abstract description 10
- 210000004080 milk Anatomy 0.000 claims abstract description 10
- 229920001184 polypeptide Polymers 0.000 claims abstract description 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract description 10
- 150000001875 compounds Chemical class 0.000 claims description 26
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 13
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims description 12
- 235000010355 mannitol Nutrition 0.000 claims description 8
- 239000000284 extract Substances 0.000 claims description 7
- 229920001353 Dextrin Polymers 0.000 claims description 6
- 239000004375 Dextrin Substances 0.000 claims description 6
- DLRVVLDZNNYCBX-UHFFFAOYSA-N Polydextrose Polymers OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(O)O1 DLRVVLDZNNYCBX-UHFFFAOYSA-N 0.000 claims description 6
- 235000019425 dextrin Nutrition 0.000 claims description 6
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 5
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 claims description 5
- 239000008101 lactose Substances 0.000 claims description 5
- 239000000845 maltitol Substances 0.000 claims description 5
- 235000010449 maltitol Nutrition 0.000 claims description 5
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 5
- 229940035436 maltitol Drugs 0.000 claims description 5
- 229940052016 turmeric extract Drugs 0.000 claims description 5
- 235000020240 turmeric extract Nutrition 0.000 claims description 5
- 239000008513 turmeric extract Substances 0.000 claims description 5
- 235000012754 curcumin Nutrition 0.000 claims description 4
- 239000004148 curcumin Substances 0.000 claims description 4
- 229940109262 curcumin Drugs 0.000 claims description 4
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims description 4
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims description 3
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 239000004386 Erythritol Substances 0.000 claims description 3
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims description 3
- 229930091371 Fructose Natural products 0.000 claims description 3
- 239000005715 Fructose Substances 0.000 claims description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 3
- 241000168517 Haematococcus lacustris Species 0.000 claims description 3
- 229920002774 Maltodextrin Polymers 0.000 claims description 3
- 239000005913 Maltodextrin Substances 0.000 claims description 3
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims description 3
- 229930195725 Mannitol Natural products 0.000 claims description 3
- 239000004368 Modified starch Substances 0.000 claims description 3
- 229920000881 Modified starch Polymers 0.000 claims description 3
- 229920001100 Polydextrose Polymers 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 3
- FYGDTMLNYKFZSV-DZOUCCHMSA-N alpha-D-Glcp-(1->4)-alpha-D-Glcp-(1->4)-D-Glcp Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](O[C@@H]2[C@H](OC(O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-DZOUCCHMSA-N 0.000 claims description 3
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims description 3
- 235000019414 erythritol Nutrition 0.000 claims description 3
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims description 3
- 229940009714 erythritol Drugs 0.000 claims description 3
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 claims description 3
- 229940107187 fructooligosaccharide Drugs 0.000 claims description 3
- 235000021255 galacto-oligosaccharides Nutrition 0.000 claims description 3
- 150000003271 galactooligosaccharides Chemical class 0.000 claims description 3
- 239000008103 glucose Substances 0.000 claims description 3
- 239000000905 isomalt Substances 0.000 claims description 3
- 235000010439 isomalt Nutrition 0.000 claims description 3
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 claims description 3
- 229940035034 maltodextrin Drugs 0.000 claims description 3
- 239000000594 mannitol Substances 0.000 claims description 3
- 229960001855 mannitol Drugs 0.000 claims description 3
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 3
- 239000003094 microcapsule Substances 0.000 claims description 3
- 235000019426 modified starch Nutrition 0.000 claims description 3
- 150000003904 phospholipids Chemical class 0.000 claims description 3
- 239000001259 polydextrose Substances 0.000 claims description 3
- 235000013856 polydextrose Nutrition 0.000 claims description 3
- 229940035035 polydextrose Drugs 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 235000010356 sorbitol Nutrition 0.000 claims description 3
- 229960002920 sorbitol Drugs 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 235000020357 syrup Nutrition 0.000 claims description 3
- 239000006188 syrup Substances 0.000 claims description 3
- 239000000811 xylitol Substances 0.000 claims description 3
- 235000010447 xylitol Nutrition 0.000 claims description 3
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 3
- 229960002675 xylitol Drugs 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 13
- 208000002193 Pain Diseases 0.000 abstract description 7
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 206010061218 Inflammation Diseases 0.000 abstract description 2
- 235000010208 anthocyanin Nutrition 0.000 abstract description 2
- 239000004410 anthocyanin Substances 0.000 abstract description 2
- 229930002877 anthocyanin Natural products 0.000 abstract description 2
- 150000004636 anthocyanins Chemical class 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 210000004369 blood Anatomy 0.000 abstract description 2
- 230000002175 menstrual effect Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000004936 stimulating effect Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 235000013305 food Nutrition 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000002994 raw material Substances 0.000 description 5
- 235000014375 Curcuma Nutrition 0.000 description 4
- -1 phospholipid compound Chemical class 0.000 description 4
- 238000009475 tablet pressing Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 235000009001 Quillaja saponaria Nutrition 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 230000000391 smoking effect Effects 0.000 description 2
- 208000007848 Alcoholism Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 description 1
- 241001092473 Quillaja Species 0.000 description 1
- 241001454523 Quillaja saponaria Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 201000007930 alcohol dependence Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/44—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Endocrinology (AREA)
- Alternative & Traditional Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composite tablet candy capable of improving symptoms of female dysmenorrhea, which comprises the following main components: turmeric, sugar alcohol, astaxanthin powder, sugar, magnesium stearate, blueberry powder, cinnamon powder, donkey-hide gelatin peptide and milk polypeptide. According to the invention, turmeric, astaxanthin powder, blueberry powder, cinnamon powder, donkey-hide gelatin peptide, milk polypeptide, sugar or sugar alcohol are mixed, and tabletting candy with scientific beneficial substance ratio is prepared by tabletting technology, so that the tabletting candy is more suitable for modern young women, wherein the turmeric has the effects of breaking blood and promoting qi circulation, and stimulating menstrual flow and relieving pain, and has obvious effects in the aspects of resisting inflammation and the like, and blueberry anthocyanin contained in the blueberry powder has obvious effects in the aspect of treating primary dysmenorrhea.
Description
Technical Field
The invention relates to the technical field of food processing, in particular to a composite tablet candy capable of improving female dysmenorrheal symptoms.
Background
Dysmenorrhea is the most common symptom in gynecology, uncomfortable symptoms such as lower abdomen cramping pain, falling and swelling, headache, lumbocrural pain and the like appear before and after menstruation or during menstruation, the dysmenorrhea is a big problem troubling women all the time, the life quality of the women is seriously affected, and the female dysmenorrhea is one of the problems which are not overcome in the current medicine.
Dysmenorrhea needs to be relieved by a medicine-food homologous product in the treatment process, but the existing medicine-food homologous product has poor treatment effect, and can generate the phenomenon of aggravation of pain when suffering from climate change, eating irritant food, smoking, alcoholism, over-pressure and the like, so that the requirement of carrying and using of a patient cannot be met.
Disclosure of Invention
In order to solve the problems in the background art, the invention aims to provide a composite tablet candy capable of improving female dysmenorrheal symptoms, which has the advantage of improving the dysmenorrheal relieving effect on the basis of convenient carrying, and solves the problems that the existing medicinal and edible products have poor treatment effect, and can not meet the portable use requirements of patients due to the phenomenon of aggravation of pain caused by climate change, irritating food eating, excessive smoking and drinking, excessive pressure and the like.
In order to achieve the purpose, the invention provides the following technical scheme: a composite tablet candy capable of improving female dysmenorrheal symptoms comprises the following main components: turmeric, sugar alcohol, astaxanthin powder, sugar, magnesium stearate, blueberry powder, cinnamon powder, donkey-hide gelatin peptide and milk polypeptide.
Preferably, the composite tablet candy comprises the following components in parts by weight: 15-85 parts of turmeric, 15-50 parts of sugar alcohol, 0-40 parts of astaxanthin powder, 0-30 parts of sugar, 0.1-1.5 parts of magnesium stearate, 0-10 parts of blueberry powder, 0-10 parts of cinnamon powder, 0-5 parts of donkey-hide gelatin peptide and 0-5 parts of milk polypeptide.
Preferably, the curcumin content of the turmeric is 5 to 95 wt%.
Preferably, the astaxanthin content in the astaxanthin powder is 1-10 wt%.
In the present invention, the sugar alcohol is preferably any one or a combination of more of D-mannitol, erythritol, isomalt, sorbitol, mannitol, xylitol and maltitol.
Preferably, the astaxanthin powder is one or the combination of haematococcus pluvialis powder and astaxanthin microcapsule powder.
Preferably, the sugar is any one or combination of more of lactose, sucrose, maltose, maltodextrin, glucose syrup, dextrin, isomaltooligosaccharide, maltooligosaccharide, fructooligosaccharide, galactooligosaccharide, fructose, resistant dextrin, polydextrose, starch and modified starch.
Preferably, the turmeric is one or the combination of a complex of turmeric extract and phospholipid or a complex of turmeric extract and quillaia bark extract.
Compared with the prior art, the invention has the following beneficial effects:
1. the invention mixes turmeric, astaxanthin powder, blueberry powder, cinnamon powder, donkey-hide gelatin peptide, milk polypeptide, sugar or sugar alcohol, and prepares the tabletting candy with scientific and beneficial substance ratio by tabletting technology, which is more suitable for the use of modern young women, wherein, the turmeric has the functions of breaking blood and promoting qi circulation, and stimulating menstrual flow and relieving pain, and also has significant effect in the aspects of anti-inflammation, etc., the bioavailability of the turmeric phospholipid compound or the turmeric soap bark extract compound used in the invention is more than 2 times of that of common curcumin, so the effect is more significant, the blueberry anthocyanin contained in the blueberry powder has significant effect in the aspect of treating primary dysmenorrhea, the cinnamon has the effects of dispelling cold and relieving pain, and warming and dredging meridians, and is one of the medicine and food for treating dysmenorrhea in the aspect of improving female dysmenorrhea, the effect is significant and has no toxic or side effect, moreover, the raw materials adopted by the invention all accord with the national food safety standard, and the invention is safe and reliable, has good taste and is convenient to eat.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention provides a composite tablet candy capable of improving symptoms of female dysmenorrhea, which comprises the following main components: turmeric, sugar alcohol, astaxanthin powder, sugar, magnesium stearate, blueberry powder, cinnamon powder, donkey-hide gelatin peptide and milk polypeptide.
The invention is further configured to: the composite tablet candy comprises the following components in parts by weight: 15-85 parts of turmeric, 15-50 parts of sugar alcohol, 0-40 parts of astaxanthin powder, 0-30 parts of sugar, 0.1-1.5 parts of magnesium stearate, 0-10 parts of blueberry powder, 0-10 parts of cinnamon powder, 0-5 parts of donkey-hide gelatin peptide and 0-5 parts of milk polypeptide.
The invention is further configured to: the curcumin content of Curcuma rhizome is 5-95 wt%.
The invention is further configured to: the astaxanthin content in the astaxanthin powder is 1-10 wt%.
The invention is further configured to: the sugar alcohol is any one or combination of more of D-mannitol, erythritol, isomalt, sorbitol, mannitol, xylitol and maltitol.
The invention is further configured to: the astaxanthin powder is one or the combination of haematococcus pluvialis powder and astaxanthin microcapsule powder.
The invention is further configured to: the sugar is any one or combination of lactose, sucrose, maltose, maltodextrin, glucose syrup, dextrin, isomaltooligosaccharide, maltooligosaccharide, fructo-oligosaccharide, galacto-oligosaccharide, fructose, resistant dextrin, polydextrose, starch and modified starch.
The invention is further configured to: the Curcuma rhizome is one or two of Curcuma rhizome extract and phospholipid complex or Curcuma rhizome extract and cortex Gleditsiae Abnormalis extract complex.
The composite tablet candy for improving female dysmenorrheal symptoms, which is provided by the invention, comprises the following examples:
example 1:
a composite tablet candy for improving female dysmenorrhea is prepared from the following raw materials in parts by weight: 49 parts of turmeric phospholipid compound, 25 parts of maltitol, 24 parts of lactose, 0.8 part of magnesium stearate, 0.4 part of blueberry powder, 0.4 part of cinnamon powder and 0.4 part of donkey-hide gelatin peptide, wherein the materials are prepared into the compound tablet candy by a tablet pressing technology, and the compound tablet candy is swallowed after being pressed into tablets at a dose of 0.51g per tablet and 2 tablets each time 2 times a day.
Example 2:
a composite tablet candy for improving female dysmenorrhea is prepared from the following raw materials in parts by weight: 40 parts of turmeric phospholipid compound, 30 parts of maltitol, 27.5 parts of lactose, 0.9 part of magnesium stearate, 0.4 part of blueberry powder, 0.4 part of cinnamon powder, 0.3 part of donkey-hide gelatin peptide and 0.5 part of milk polypeptide, wherein the materials are prepared into the compound tablet candy by a tablet pressing technology, and the compound tablet candy is swallowed by 2 tablets each time and 0.63g per tablet per day.
Example 3:
a composite tablet candy for improving female dysmenorrhea is prepared from the following raw materials in parts by weight: 35 parts of a compound of a turmeric extract and a quillaja bark extract, 35 parts of D-mannitol, 27.6 parts of isomaltose hypgather, 0.9 part of magnesium stearate, 0.5 part of blueberry powder, 0.5 part of cinnamon powder and 0.5 part of donkey-hide gelatin peptide, wherein the compound is prepared into compound tablet candy by a tablet pressing technology, and the compound tablet candy is swallowed 2 tablets each time and 0.72g per tablet 2 times a day.
Example 4:
a composite tablet candy for improving female dysmenorrhea is prepared from the following raw materials in parts by weight: 45 parts of turmeric phospholipid compound, 28 parts of D-mannitol, 25 parts of isomaltooligosaccharide, 0.8 part of magnesium stearate, 0.4 part of blueberry powder, 0.4 part of cinnamon powder and 0.4 part of donkey-hide gelatin peptide, wherein the materials are prepared into the compound tablet candy by a tablet pressing technology, and the compound tablet candy is swallowed by 2 tablets each time and 0.56g per tablet per day.
Example 5:
human body trial test: female volunteers with dysmenorrhea symptoms were recruited by using a self-control design, and volunteers should participate voluntarily.
Test protocol: 120 volunteers were recruited as samples, divided into 4 groups of 30 persons, and the patients were taken according to the administration method in the examples, swallowed, and administered for 60 days; during taking the product, volunteers are required to stop taking all medicines or foods capable of treating or relieving dysmenorrheal symptoms to eliminate influence.
And (3) test results:
in a normal experimental environment: example 1 comprises 30 samples, wherein the effective rate is 73.3% when 5 persons, 17 persons and 8 persons are effective and ineffective;
in a normal experimental environment: example 2 comprises 30 samples, wherein the effective rate is 73.3% when 6 persons, 16 persons and 8 persons are effective and ineffective;
in a normal experimental environment: example 3 comprises 30 samples, wherein 8 effective patients, 16 effective patients and 6 ineffective patients are remarkably effective, and the effective rate is 75%;
in a normal experimental environment: example 4 contained 30 samples, with a significant 8, 15, and 7 effective, response rates of 74.6%.
The test result of human trial administration shows that the compound tablet candy of the invention has good improvement effect on dysmenorrheal symptoms with different degrees when being taken, but no side effect is found.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A composite tablet candy capable of improving female dysmenorrheal symptoms is characterized in that: the main components of the composite tablet candy are as follows: turmeric, sugar alcohol, astaxanthin powder, sugar, magnesium stearate, blueberry powder, cinnamon powder, donkey-hide gelatin peptide and milk polypeptide.
2. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the composite tablet candy comprises the following components in parts by weight: 15-85 parts of turmeric, 15-50 parts of sugar alcohol, 0-40 parts of astaxanthin powder, 0-30 parts of sugar, 0.1-1.5 parts of magnesium stearate, 0-10 parts of blueberry powder, 0-10 parts of cinnamon powder, 0-5 parts of donkey-hide gelatin peptide and 0-5 parts of milk polypeptide.
3. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the curcumin content of the turmeric is 5-95 wt%.
4. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the astaxanthin content in the astaxanthin powder is 1-10 wt%.
5. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the sugar alcohol is any one or combination of more of D-mannitol, erythritol, isomalt, sorbitol, mannitol, xylitol and maltitol.
6. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the astaxanthin powder is one or the combination of haematococcus pluvialis powder and astaxanthin microcapsule powder.
7. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the sugar is any one or combination of more of lactose, sucrose, maltose, maltodextrin, glucose syrup, dextrin, isomaltooligosaccharide, maltooligosaccharide, fructo-oligosaccharide, galacto-oligosaccharide, fructose, resistant dextrin, polydextrose, starch and modified starch.
8. The compound tabletted candy as claimed in claim 1, wherein the compound tabletted candy is capable of improving symptoms of female dysmenorrhea and is characterized in that: the turmeric is one or the combination of two of a complex of turmeric extract and phospholipid or a complex of turmeric extract and quillaia bark extract.
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| CN202210128273.9A CN114431328A (en) | 2022-02-11 | 2022-02-11 | Composite tablet candy capable of improving symptoms of female dysmenorrhea |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115671238A (en) * | 2022-11-08 | 2023-02-03 | 广州四季泰来生物技术有限公司 | Formula and preparation process of nutritional supplement for improving secondary ovarian function decline of women of childbearing age |
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| CN109601680A (en) * | 2019-01-17 | 2019-04-12 | 云南龙布瑞生物科技有限公司 | A kind of maintenance joint and the Astaxanthin In Haematococcus Pluvialis pressed candy of connective tissue health and preparation method thereof |
| CN111345388A (en) * | 2020-04-07 | 2020-06-30 | 亳州寿叶生物科技有限公司 | Method and equipment for preparing tablet candy with liver protecting, spleen invigorating and anti-tumor effects |
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- 2022-02-11 CN CN202210128273.9A patent/CN114431328A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109601680A (en) * | 2019-01-17 | 2019-04-12 | 云南龙布瑞生物科技有限公司 | A kind of maintenance joint and the Astaxanthin In Haematococcus Pluvialis pressed candy of connective tissue health and preparation method thereof |
| CN111345388A (en) * | 2020-04-07 | 2020-06-30 | 亳州寿叶生物科技有限公司 | Method and equipment for preparing tablet candy with liver protecting, spleen invigorating and anti-tumor effects |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115671238A (en) * | 2022-11-08 | 2023-02-03 | 广州四季泰来生物技术有限公司 | Formula and preparation process of nutritional supplement for improving secondary ovarian function decline of women of childbearing age |
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