CN114366728A - Carsickness-preventing essential oil, carsickness-preventing fragrance material and fragrance generator - Google Patents
Carsickness-preventing essential oil, carsickness-preventing fragrance material and fragrance generator Download PDFInfo
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- CN114366728A CN114366728A CN202210036839.5A CN202210036839A CN114366728A CN 114366728 A CN114366728 A CN 114366728A CN 202210036839 A CN202210036839 A CN 202210036839A CN 114366728 A CN114366728 A CN 114366728A
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- perilla
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Abstract
The invention provides carsickness-preventing essential oil, a carsickness-preventing fragrance material and a fragrance generator, wherein the carsickness-preventing essential oil comprises the following raw materials in parts by weight: 45% of peppermint oil, 25% of ginger oil, 15% of citrus extract, 5% of angelica extract, 5% of perilla extract and 5% of patchouli oil. The invention has the advantages of good safety, environmental tolerance, durability and the like, and can be particularly used for preventing carsickness.
Description
Technical Field
The invention belongs to the field of medicines and the technical field of vehicle-mounted fragrance, and particularly relates to carsickness-preventing essential oil, a carsickness-preventing fragrance material and a fragrance generator.
Background
The environment in the automobile is an important component of the daily living environment of people, and is more and more concerned by customers, so that the development work of building a high-efficiency environment-friendly, anti-germ and self-cleaning automobile moving space and starting a healthy automobile is imperative. At present, the atmosphere in a vehicle is often regulated through fragrance essential oil, most of common fragrances are prepared by modulating essence, and the fragrance can generate side effects on a human body, for example, patent document CN112538399A discloses a vehicle-mounted fragrance and a preparation method thereof, which can effectively improve the problem of peculiar smell in the vehicle, effectively improve the quality of the smell sense organ in the vehicle and the commodity of the vehicle, and have obvious brand recognition, but the fragrance contains a large amount of essence and chemical components and can possibly generate adverse effects on the human body.
Carsickness is easy to happen when people take electric vehicles, people can choose to take carsickness prevention medicines, but the ingredients of thevenin and the like in the traditional carsickness medicines are the ingredients of neuroleptic, and the ingredients can bring adverse effects on human health and driving safety. For example, patent document CN107510845A discloses a car sickness drug for regulating brain functions, which comprises a pharmaceutically active ingredient and an auxiliary material, wherein the pharmaceutically active ingredient comprises benzodiazepines, piracetam, glucocorticoid and metoclopramide, and the car sickness drug has high biological toxicity and is easy to generate side effects.
In order to meet the diversified demands of consumers, traditional Chinese medicine components without stimulation and side effects are gradually developed in the prior art to prepare a fragrance material with an anti-carsickness effect, for example, patent document CN107184754A discloses an smelling carsickness medicament and a preparation method thereof, wherein the components comprise 3-6 parts of flowers, 2-4 parts of artemisia annua, 2-4 parts of fragrant rods and 3-6 parts of lysimachia christinae hance, the important components are crushed and placed in a packaging bag, and the carsickness relieving effect is achieved by smelling the components. However, the existing fragrant materials taking traditional Chinese medicines as active ingredients usually have the defects of poor environmental tolerance, poor persistence and the like, and the carsickness materials in the prior art are basically reused when carsickness symptoms appear and used for relieving carsickness, and the carsickness prevention materials suitable for preventing carsickness are rarely researched and reported.
In view of the above, it is an urgent need to solve the problem of the art to provide an anti-carsickness essential oil which can prevent carsickness and has good safety, environmental tolerance and durability.
Disclosure of Invention
The invention provides carsickness-preventing essential oil, a carsickness-preventing fragrance material and a fragrance generator, which have the advantages of good safety, environmental tolerance, durability and the like, can be particularly used for preventing carsickness and can effectively overcome the defects in the prior art.
On one aspect of the invention, the carsickness prevention essential oil is provided and comprises the following raw materials in parts by weight: 40-50% of peppermint oil, 20-30% of ginger oil, 10-20% of citrus extract, 3-7% of angelica extract, 3-7% of perilla extract and 3-7% of patchouli oil.
According to an embodiment of the present invention, the angelica sinensis extract is prepared according to a preparation process comprising the steps of: soaking radix Angelicae sinensis in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain radix Angelicae sinensis extractive solution; wherein, the concentration of the angelica sinensis extract is controlled to meet the following requirements: the ratio of the volume of the angelica extract to the mass of the angelica raw material is 3mL-7 mL: 1g of the total weight of the composition.
According to an embodiment of the present invention, the perilla extract is prepared according to a preparation process comprising the steps of: soaking Perillae herba in ethanol solution for 0.3-0.7 hr, decocting, filtering, and concentrating the filtrate to obtain Perillae herba extractive solution; wherein, the concentration of the perilla extract is controlled to meet the following requirements: the ratio of the volume of the perilla extracting solution to the mass of the perilla raw material is 3-6 mL: 1g of the total weight of the composition.
According to one embodiment of the present invention, the citrus extract is prepared according to a process comprising the steps of: soaking pericarpium Citri Tangerinae in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain citrus extract; wherein, the concentration of the citrus extract is controlled to meet the following requirements: the ratio of the volume of the citrus extract to the mass of the dried orange peel raw material is 3mL-6 mL: 1g of a compound; and/or, the peppermint oil is prepared according to the preparation process comprising the following steps: soaking a mint leaf raw material in a soluble salt solution, distilling to obtain a distillate, removing a water phase in the distillate to obtain mint oil, wherein the ratio of the mass of the mint leaf raw material to the volume of the soluble salt solution is 1: 9-13; and/or, the ginger oil is prepared according to the preparation process comprising the following steps: drying the ginger raw material, grinding the dried ginger raw material into ginger powder, mixing the ginger powder with diethyl ether, treating the mixture at 45-50 ℃ for 30min, then filtering the mixture, filtering the obtained first filtrate under reduced pressure, and collecting a second filtrate to obtain ginger oil, wherein the ratio of the mass of the ginger powder to the volume of the diethyl ether is 1: 2-5; and/or, the patchouli oil is prepared according to the preparation process comprising the following steps: drying and grinding agastache rugosus raw materials into agastache rugosus powder, adding water for distillation to obtain distillate, and removing a water phase in the distillate to obtain the agastache rugosus oil, wherein the mass ratio of the agastache rugosus powder to the water is 1: 3-7.
In a second aspect of the invention, there is provided an anti-carsickness fragrance material comprising a carrier matrix and the anti-carsickness essential oil, wherein the carrier matrix comprises at least one of gel, ethylene-vinyl acetate copolymer, ceramic and gypsum.
In a third aspect of the present invention, there is provided a fragrance generator comprising: the fragrance container is used for containing the carsickness-preventing fragrance material; the fragrance container is provided with a fragrance outlet for emitting fragrance generated by the carsickness-preventing fragrance material; and the chip is connected with the fragrance container and is used for obtaining the residual amount of the carsickness-preventing fragrance material in the fragrance container.
According to one embodiment of the invention, the number of the fragrance containers is at least two, each fragrance container is provided with an independent fragrance outlet, and the fragrance outlet of each fragrance container is provided with a switch.
According to an embodiment of the invention, the perfume device further comprises at least two perfume outlet pipes, each perfume container is provided with an independent perfume outlet, and the perfume outlet of each perfume container is communicated with the perfume outlet pipe.
According to one embodiment of the invention, the car sickness prevention fragrance container further comprises a fan matched with the fragrance container and used for blowing out the fragrance generated by the car sickness prevention fragrance materials in the fragrance container.
According to one embodiment of the invention, the number of fragrance containers is three.
The implementation of the invention has at least the following beneficial effects:
the carsickness-preventing essential oil provided by the invention adopts the traditional Chinese medicine components without stimulation and side effects as raw materials, has good safety, and meets the requirements of no toxicity and no harm to human bodies; the carsickness-preventing essential oil is in a liquid state at normal temperature, can be directly used or used after being diluted according to needs, and is flexible in application mode.
The carsickness-preventing fragrance material provided by the invention has the advantages that the natural plant essential oil is solidified into the fragrance solid by adopting the carrier matrix, so that the storage and the use are convenient, the service life of the carsickness-preventing fragrance material is further prolonged, carsickness of drivers and passengers can be relieved by the carsickness-preventing fragrance material, the defect that the driving safety of drivers is influenced by common carsickness medicines is overcome, carsickness can be prevented at the same time, and the carsickness-preventing fragrance material has excellent safety and carsickness-preventing effect.
The fragrance generator provided by the invention can be used as a vehicle-mounted fragrance generator to be matched with other parts in a vehicle, so that good sensory experience can be brought to drivers and passengers, and the carsickness prevention effect can be realized. The chip in the fragrance generator can identify the emission parameters and the service life of the anti-carsickness fragrance material in the fragrance generator, and timely remind customers of replacing and adjusting products; the customer can switch or switch the anti-carsickness fragrance material as required, fragrance emission of the customer when the fragrance is not needed is avoided, meanwhile, the fragrance generator has good appearance design, the sense organ of the product is high-grade, and the confidence of the customer on the product can be improved.
The carsickness-preventing essential oil, the carsickness-preventing fragrance material and the fragrance generator provided by the invention can realize the carsickness-preventing effect and meet the requirements of no toxicity and no harm to human bodies.
Drawings
FIG. 1 is a fragrance generator according to one embodiment of the present invention;
FIG. 2 is a diagram of an identification chip in a fragrance generator according to an embodiment of the present invention;
FIG. 3 is a perspective view of a fragrance container in a fragrance generator according to an embodiment of the present invention.
Detailed Description
In order that those skilled in the art will better understand the concept of the present invention, the following detailed description is given with reference to the accompanying drawings.
The carsickness prevention essential oil provided by the invention comprises the following raw materials in parts by weight: 40-50% of peppermint oil, 20-30% of ginger oil, 10-20% of citrus extract, 3-7% of angelica extract, 3-7% of perilla extract and 3-7% of patchouli oil.
Specifically, the carsickness prevention essential oil comprises six traditional Chinese medicine components of angelica, purple perilla, citrus, peppermint oil, ginger oil and palchouli oil, wherein the angelica has the effects of nourishing blood, promoting blood circulation and removing obstruction in channels to relieve pain, and contains active medicine components; the perilla and the agastache are main components of the ageratum vital qi powder, have the effects of relieving exterior syndrome, regulating the middle warmer, regulating qi and resolving dampness, especially have the effect of relieving symptoms such as damp turbidity vertigo and can relieve vertigo caused by sultriness in the riding process. Citrus reticulata is called as dried orange peel in traditional Chinese medicine, has the effects of harmonizing stomach and reducing phlegm, and is often prepared into Erchen decoction with pinellia ternate and other components to treat wind-phlegm disturbing type vertigo. The mint leaves are usually used for cooling and invigorating stomach, have the effects of inducing resuscitation and restoring consciousness, and the mint oil prepared from the mint leaves has the effect of relieving nasal dryness and can also relieve symptoms of nausea and vomiting and the like of patients after general anesthesia. The research of ginger shows that the ginger can prevent and treat motion sickness such as sea sickness, carsickness and the like by regulating the gastrointestinal function. The carsickness-preventing essential oil prepared from the components can improve the peculiar smell in a car, has the carsickness-preventing effect, and ensures the safety of the carsickness-preventing essential oil by the traditional Chinese medicine components.
In the anti-carsickness essential oil, the mass content of the mint oil is 40% -50%, such as 40%, 42%, 45%, 48%, 50% or the range of any two of the above components; the ginger oil is 20-30% by mass, for example 20%, 22%, 25%, 28%, 30% or any two of them; the mass content of the citrus extract is 10% -20%, for example 10%, 12%, 15%, 18%, 20% or any two of them; the mass content of the angelica sinensis extract is 3% -7%, for example, 3%, 4%, 5%, 6%, 7% or the range of any two of them; the mass content of the perilla extract is 3% -7%, for example, 3%, 4%, 5%, 6%, 7% or any two of them; the patchouli oil is present in an amount of 3% to 7% by mass, for example 3%, 4%, 5%, 6%, 7% or any combination of both.
Specifically, the preparation method of the carsickness prevention essential oil comprises the following steps: adding the angelica sinensis extract, the perilla herb extract and the citrus extract meeting the quality component requirements into a stirrer, uniformly stirring, adding the peppermint oil, the ginger oil and the agastache oil, stirring uniformly to obtain a mixed liquid, and placing the mixed liquid into a distillation flask for distillation treatment to obtain the carsickness-preventing essential oil, wherein the distillation treatment conditions are as follows: the distillation temperature is 50 ℃, and the distillation time is 2-3 hours. And cooling the prepared carsickness prevention essential oil to room temperature, and pouring the cooled carsickness prevention essential oil into a prepared packaging bottle for sealed storage. The carsickness-preventing essential oil is in a liquid state at normal temperature and can be directly used or diluted for reuse according to needs.
In some embodiments, the angelica sinensis extract is prepared according to a preparation process comprising the following steps: soaking radix Angelicae sinensis in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain radix Angelicae sinensis extractive solution; wherein, the soaking time is, for example, 0.5 hour, 0.8 hour, 1 hour, 1.5 hours or any two of the ranges, and the concentration of the angelica sinensis extract is controlled to satisfy: the ratio of the volume of the angelica extract to the mass of the angelica raw material is 3mL-7 mL: 1g, e.g. 3 mL: 1g, 4 mL: 1g, 5 mL: 1g, 6 mL: 1g, 7 mL: 1g or any two thereof.
In the specific implementation of the invention, the preparation process of the angelica sinensis extract comprises the following steps: weighing a proper amount of Chinese angelica raw materials, soaking the Chinese angelica raw materials in water for 1h, adding water, heating and decocting for 3h, and filtering to obtain a first Chinese angelica filtrate and a first Chinese angelica, wherein the mass ratio of the added water to the Chinese angelica raw materials is 15: 1; adding water into the first angelica, heating and decocting for 0.5h, and filtering to obtain a second angelica filtrate and a second angelica, wherein the mass ratio of the added water to the first angelica is 8: 1; adding water into the second angelica, heating and decocting for 0.5h, and filtering to obtain a third angelica filtrate and a third angelica, wherein the ratio of the added water to the second angelica is 8: 1, then; and (3) mixing the first angelica filtrate, the second angelica filtrate and the third angelica filtrate to obtain a total angelica filtrate, and concentrating the total angelica filtrate to obtain an angelica extract, wherein the ratio of the volume of the angelica extract to the mass of the angelica raw material is 5 mL: 1g, wherein the decoction process can be carried out according to the conventional decoction method in the field.
In some embodiments, the perilla extract is prepared according to a preparation process comprising the steps of: soaking Perillae herba in ethanol solution for 0.3-0.7 hr, decocting, filtering, and concentrating the filtrate to obtain Perillae herba extractive solution; wherein the soaking time is, for example, 0.3 hour, 0.5 hour, 0.6 hour, 0.7 hour, or a range consisting of any two thereof; controlling the concentration of the perilla extract to meet the following conditions: the ratio of the volume of the perilla extracting solution to the mass of the perilla raw material is 3-6 mL: 1g, e.g. 3 mL: 1g, 4 mL: 1g, 5 mL: 1g, 6 mL: 1g or any two thereof.
In the specific implementation of the invention, the preparation process of the perilla extract comprises the following steps: weighing an appropriate amount of perilla raw materials, adding the perilla raw materials into an ethanol solution, soaking for 0.5h, adding ethanol, heating and decocting for 2h, and filtering to obtain a first perilla filtrate and a first perilla, wherein the mass ratio of the added ethanol to the perilla raw materials is 25: 1; adding ethanol into the first perilla, heating and decocting for 1.5h, and filtering to obtain a second perilla filtrate and a second perilla, wherein the mass ratio of the added ethanol to the first perilla is 20: 1; adding ethanol into the second perilla, heating and decocting for 2h, and filtering to obtain a third perilla filtrate and a third perilla, wherein the ratio of the added ethanol to the second perilla is 16: 1; mixing the first perilla filtrate, the second perilla filtrate and the third perilla filtrate to obtain a total perilla filtrate, and concentrating the total perilla filtrate to obtain a perilla extracting solution, wherein the mass ratio of the volume of the perilla extracting solution to the perilla raw materials is 4 mL: 1g, wherein the ethanol solution has a mass percentage concentration of 80%, four layers of gauze are adopted for filtering, and the decoction process can be carried out according to a conventional decoction method in the field.
In some embodiments, the citrus extract is prepared according to a process comprising the steps of: soaking pericarpium Citri Tangerinae in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain citrus extract; wherein the soaking time is, for example, 0.5 hour, 0.8 hour, 1 hour, 1.5 hours, or any two thereof; controlling the concentration of the orange extract to meet the following conditions: the ratio of the volume of the citrus extract to the mass of the dried orange peel raw material is 3mL-6 mL: 1g, e.g. 3 mL: 1g, 4 mL: 1g, 5 mL: 1g, 6 mL: 1g or any two thereof.
Specifically, the preparation process of the citrus extract comprises the following steps: weighing a proper amount of dried orange peel raw materials, soaking the dried orange peel raw materials in water for 1 hour, adding water with the mass of 20 times that of the dried orange peel raw materials, heating and decocting for 1.5 hours, filtering to obtain a first orange filtrate and a first orange, adding water with the mass of 12 times that of the first orange into the first orange, decocting for 1.5 hours, and filtering to obtain a second orange filtrate and a second orange; adding water in an amount which is 4 times the weight of the second citrus into the second citrus, heating and decocting, and filtering to obtain a third citrus filtrate and a third citrus; and combining the first citrus filtrate, the second citrus filtrate and the third citrus filtrate to obtain a total citrus filtrate, and concentrating the total citrus filtrate to obtain a citrus extract, so that the volume of the citrus extract and the mass ratio of the raw material of the dried orange peel are 4 mL: 1g, wherein the filtration is carried out by adopting double-layer gauze.
In some embodiments, the peppermint oil is prepared according to a preparation process comprising the steps of: soaking a mint leaf raw material in a soluble salt solution, distilling to obtain a distillate, removing a water phase in the distillate to obtain mint oil, wherein the ratio of the mass of the mint leaf raw material to the volume of the soluble salt solution is 1: 9-13, e.g. 1: 9. 1: 10. 1: 11. 1: 12. 1: 13, or any two thereof. The soluble salt includes, for example, sodium chloride, and the like, and the soluble salt solution may specifically be a soluble salt aqueous solution in which the soluble salt is dissolved in water, and includes, for example, a sodium chloride solution, and the concentration of the sodium chloride solution may be 2%.
In the specific implementation of the invention, a proper amount of dried mint leaves are weighed as mint raw materials, the mint raw materials are soaked in a soluble salt solution at room temperature, then the mint raw materials and the soluble salt solution are transferred into a distillation device for distillation treatment for 3 hours to obtain distillate, the distillate is kept stand for layering, and then upper-layer essential oil is collected, namely the mint oil, wherein the volume ratio (material-to-liquid ratio) of the mint raw materials to the soluble salt solution is 1: 11.
In some embodiments, the ginger oil is prepared according to a preparation process comprising the following steps: drying the ginger raw material, grinding the dried ginger raw material into ginger powder, mixing the ginger powder with diethyl ether, treating the mixture at 45-50 ℃ for 30min, then filtering the mixture, filtering the obtained first filtrate under reduced pressure, and collecting a second filtrate to obtain ginger oil, wherein the ratio of the mass of the powder to the volume of the diethyl ether is 1: 2-5, e.g. 1: 2. 1: 3. 1: 3.5, 1: 4. 1: 5 or any two thereof.
In the specific implementation of the invention, a proper amount of ginger is cleaned, sliced and dried, then ground into powder, the powder is sieved by a 60-80 mesh sieve to obtain ginger powder, ether is added into the ginger powder, extraction is carried out for 30min under the condition of water bath at 45-50 ℃ to obtain extract liquor, then the extract liquor is filtered to obtain first filtrate, the obtained first filtrate is subjected to reduced pressure filtration, and second filtrate is collected to obtain ginger oil, wherein the drying condition is as follows: the drying temperature is 60 ℃, the drying time is 1h, and the ratio of the mass of the ginger powder to the volume of the diethyl ether is 1: 3.
in some embodiments, the patchouli oil is prepared according to a preparation process comprising the steps of: drying and grinding agastache rugosus raw materials into agastache rugosus powder, adding water for distillation to obtain distillate, and removing a water phase in the distillate to obtain the agastache rugosus oil, wherein the mass ratio of the agastache rugosus powder to the water is 1: 3-7, e.g. 1: 3. 1: 4. 1: 5. 1: 6. 1: 7, or any two thereof.
In the specific implementation of the invention, the patchouli leaves are cleaned and dried, placed in a blender and stirred into powder, the powder is mixed with distilled water to obtain a mixed solution, the mixed solution is distilled by adopting a steam distillation method to obtain a distillate, the distillate is sequentially extracted by using petroleum ether, diethyl ether and ethyl acetate, and the patchouli oil is obtained by adopting a reflux extraction method at the temperature of 55 ℃ after extraction, wherein the mass ratio of the powder to the distilled water is 1: 5.
the invention provides an anti-carsickness fragrant material which comprises a carrier matrix and the anti-carsickness essential oil, wherein the carrier matrix comprises at least one of gel, ethylene-vinyl acetate copolymer, ceramic and gypsum.
Specifically, the anti-carsickness essential oil is added into the carrier matrix and solidified into a solid state, so that the storage of the anti-carsickness essential oil is facilitated, the release rate of the anti-carsickness essential oil is delayed, and the flame retardance of the anti-carsickness essential oil can be improved. Common carrier substrates are gelatin, Ethylene Vinyl Acetate (EVA), ceramics, gypsum, and the like. The gel base material is adopted in the specific implementation of the invention, and has the advantages of long fragrance retention time and slow release effect. The process for preparing the anti-carsickness fragrant material by using the gel as the carrier matrix comprises the following steps: placing the compound rubber powder, agar powder and potassium chloride in a beaker, fully stirring at normal temperature until the mixture is uniformly mixed, adding ultrapure water for soaking to obtain compound gel, heating the compound gel in a water bath, stirring and dissolving the compound gel into transparent glue solution, adding the anti-carsickness essential oil, continuously stirring until the mixture is uniformly mixed to obtain mixed solution, placing the mixed solution into a split charging box for split charging, ventilating and cooling, and solidifying to obtain gel fragrance solid, namely the anti-carsickness fragrance material.
Generally, the carsickness-preventing fragrance material is placed in a container for containing the carsickness-preventing fragrance material to emit fragrance, for example, the carsickness-preventing fragrance material can be placed in a cloth bag to be made into a fragrance bag (a sachet), the fragrance is emitted through the fragrance bag, the carsickness-preventing fragrance material can also be placed in a fragrance generator in a vehicle, and the fragrance generator emits the fragrance to achieve a better carsickness-preventing effect and a better car interior fragrance sensing effect, so that the carsickness-preventing fragrance material is flexible to use.
The present invention provides a fragrance generator comprising: the fragrance container is used for containing the carsickness-preventing fragrance material; the fragrance container is provided with a fragrance outlet for emitting fragrance generated by the carsickness-preventing fragrance material; and the chip is connected with the fragrance container and is used for obtaining the residual amount of the carsickness-preventing fragrance material in the fragrance container.
Generally, the fragrance generator is a vehicle-mounted fragrance generator, the position of the fragrance generator can be adjusted as required, the fragrance generator is generally arranged in the middle of an automobile instrument desk or at the rear of an auxiliary instrument desk, the fragrance generator comprises a fragrance container and a chip, wherein the fragrance container is filled with anti-carsickness materials, the fragrance emitted by the anti-carsickness materials is emitted through a fragrance outlet of the fragrance container, and the chip is used for obtaining the residual amount of the anti-carsickness materials in the fragrance container. As shown in fig. 1 and 2, the fragrance generator includes a fragrance identification area (fragrance type identification), an identification chip (chip) in the fragrance identification area is connected to a fragrance type identification PCB, the fragrance type identification PCB can transmit information such as emission parameters of the fragrance and the remaining amount of the fragrance to a vehicle-mounted screen, and a customer can obtain the information according to the vehicle-mounted screen.
In some embodiments, the number of the fragrance containers is at least two, each fragrance container is provided with an independent fragrance outlet, and the fragrance outlet of each fragrance container is provided with a switch. Specifically, each fragrance container is provided with an independent switch, and a customer opens the fragrance container according to needs to enable the anti-carsickness fragrance material to emit fragrance from the fragrance outlet.
In some embodiments, the fragrance container further comprises at least two fragrance outlet pipes, each fragrance container is provided with an independent fragrance outlet, and the fragrance outlet of each fragrance container is communicated with the fragrance outlet pipe.
In the specific implementation of the invention, when the number of the fragrance containers is at least two, the fragrance generator further comprises a fragrance outlet pipe, the bottom of the fragrance outlet pipe comprises an air inlet pipe perpendicular to the fragrance outlet pipe, and a fragrance outlet of the fragrance container is communicated with the fragrance outlet pipe through the air inlet pipe.
In some embodiments, a fan is further included that cooperates with the fragrance container to blow out the fragrance created by the anti-carsickness fragrance material in the fragrance container.
Specifically, the fragrance with different concentrations can be obtained by controlling the wind speed of the fan, in the specific implementation of the invention, the fragrance outlet of the fragrance generator is connected with the main air pipe of the air-conditioning blowing surface in the vehicle through the air guide pipeline, so that the fragrance emitted by the anti-carsickness fragrance material can be uniformly emitted in the vehicle, the problems of nonuniform distribution of the fragrance emitted in the vehicle and the like caused by over-low power of the fan are solved, and the anti-carsickness effect of passengers in the back row is improved.
In some embodiments, the number of the fragrance containers is three, as shown in fig. 3, the three fragrance containers are arranged side by side, specifically, as shown in fig. 1, the fragrance container a, the fragrance container B and the fragrance container C are arranged side by side, each fragrance container is provided with a chip, in the fragrance generator, fragrance outlets of the fragrance container a, the fragrance container B and the fragrance container C are connected by independent fragrance inlet pipes, when the three fragrance containers are in an open state, the fragrance emitted from the three fragrance containers enters respective air inlet pipes through the fragrance outlets, and the fragrance is gathered at air inlets of the fragrance outlet pipes and emitted through the fragrance outlets of the fragrance outlet pipes.
The present invention will be further illustrated by the following specific examples and comparative examples.
Example 1
Adding the angelica sinensis extract, the perilla extract and the citrus extract into a stirrer, stirring for 60 minutes, adding the peppermint oil, the ginger oil and the agastache rugosus oil, stirring for 80 minutes again to obtain a mixed liquid, and placing the mixed liquid into a distillation flask for distillation treatment to obtain the carsickness-prevention essential oil, wherein the conditions of the distillation treatment are as follows: distilling at 50 deg.C for 2 hr, cooling the carsickness preventing essential oil to room temperature, and sealing in a packaging bottle; wherein the components meet the following weight portions: 45% of peppermint oil, 25% of ginger oil, 15% of citrus extract, 5% of angelica extract, 5% of perilla extract and 5% of patchouli oil;
placing the compound rubber powder, agar powder and potassium chloride in a beaker, fully stirring at normal temperature until the mixture is uniformly mixed, adding ultrapure water for soaking to obtain compound gel, heating the compound gel in a water bath, stirring and dissolving the compound gel into transparent glue solution, adding the anti-carsickness essential oil, continuously stirring until the mixture is uniformly mixed to obtain mixed solution, placing the mixed solution into a split charging box for split charging, ventilating and cooling, and solidifying to obtain the anti-carsickness fragrant material.
The following tests were performed on the anti-carsickness essential oils in the examples:
anti-carsickness effect test (product validity test)
1. Evaluation of animal vertigo:
taking healthy adult ICR mice, pre-stimulating the ICR mice in a low-speed centrifuge for half a minute of rotation, eliminating the mice (with the score of 0) which are not sensitive to the rotation stimulation (motion sickness), and then dividing the remaining mice into a blank control group, a positive control group and a rotation stimulation (experimental group), wherein 10 mice are used in each group, the total number of the mice is 40, the weight of the mice is 18g-22g, and the number of the mice is 20 respectively;
wherein, 1mg/kg of scopolamine is injected into the abdominal cavity of the mice of the positive control group, and physiological saline is injected into the mice of the blank control group and the experimental group; the experimental group receives high-dose and low-dose spray treatment of the anti-dizziness essential oil for 15min, and the rest group receives normal saline spray; wherein the conditions of the spray treatment are as follows: high dose is 0.03 mL/body, low dose is 0.01 mL/body, spray time: 15 min;
immediately subjecting the treated three groups of mice to a rotary stimulation treatment, wherein the rotary stimulation treatment comprises the following steps: placing the mouse into a 50mL centrifugal tube, and centrifugally rotating the mouse on a centrifugal machine at 250r/min for 30 min; wherein cotton pads are arranged at the periphery and the bottom in the centrifugal tube; the following methods were used to evaluate the extent of vertigo in mice:
1. open field behavior experiment
Placing a mouse generating vertigo in an open-air box, and recording the time taken for the belly of the mouse to be separated from the ground and the time taken for the tail to be separated from the ground (if the mouse is not completely recovered within 30min, the mouse is recorded as not recovered); the results of Kruskal-Wallis H test of each group of data are shown in table 1-1, and the overall comparison difference of abdomen off-ground time of each group of mice has statistical significance (H value is 21.564, P value is less than 0.01) and tail off-ground time of each group of mice has statistical significance (H value is 29.822, P value is less than 0.01). The results of pairwise comparison show: the abdomen off-ground time and tail off-ground time of the scopolamine group, the low dose of the anti-dizziness essence oil group and the high dose of the anti-dizziness essence oil group are both obviously lower than those of the blank group (the P value is less than 0.01).
Table 1-1 results of experiments on open field in each group of mice (n ═ 10)
2. Experiment of spontaneous Activity
The spontaneous activity experiment is an experiment for observing and researching the neuropsychiatric change of experimental animals and various behaviors after the experimental animals enter a wide environment. Mice producing vertigo were placed in a spontaneous motility apparatus and the number of movements of the mice within 5min was determined. The behavioral indexes of the spontaneous activity reduction are similar to the behavioral indexes of mental depression and reaction retardation after vertigo occurs, indirectly reflect the change of the central nervous system, and can be used as a specific index for judging the occurrence of motion sickness. The results, using one-way anova, as shown in tables 1-2, showed that the mice in each group had spontaneous activity (F-value 12.411, P-value < 0.01), and the overall comparison was statistically significant. The results of two-to-two comparison show that the scopolamine group, the low-dose anti-dizziness essential oil group and the high-dose anti-dizziness essential oil group can obviously increase the times of spontaneous activities of mice (P value is less than 0.01).
Table 1-2 experimental results of spontaneous activity of each group of mice (n ═ 10)
3. Motion sickness symptom scoring
Observing the spontaneous activity phenomena of three groups of mice, adopting halo response indexes to reflect the dizziness degree of the mice (shown in tables 1-3), namely taking excrement, urine, pilus and shiver as evaluation indexes, and quantitatively grading the dizziness degree by a method of giving scores, wherein the bigger the halo response index is, the worse the halo degree is.
TABLE 1-3 halo response index scoring tables
TABLE 1-4 evaluation test results of motion sickness symptoms in each group of mice
(n＝10)
| Group of | Total fraction of halo reaction index | t value | P value |
| Blank control group | 3.886±1.799 | — | — |
| Scopolamine group | 1.200±0.000 | 3.949 | 0.008 |
| Low dose of anti-dizziness essential oil | 1.680±1.159 | 2.855 | 0.018 |
| High-dose anti-dizziness essential oil group | 1.300±0.392 | 3.740 | 0.009 |
The total comparison difference of the abdomen off-ground time of each group of mice has statistical significance by using Kruskal-Wallis H test (H value is 17.250, P value is less than 0.01). The results of pairwise comparison show: the scopolamine group and the low-dose and high-dose anti-dizziness essential oil can reduce the dizziness reaction index (P value is less than 0.01) of the mouse.
The content of polybrominated biphenyls and polybrominated diphenyl ethers in heavy metals and non-metallic materials in the anti-carsickness fragrance material is tested according to a test method of Q/JLY J7110845B-2016, and the result shows that the test result of cadmium, lead, mercury and hexavalent chromium in the anti-carsickness fragrance material and the test result of polybrominated biphenyls and polybrominated diphenyl ethers in the non-metallic materials meet the standard Q/JL J160001-2020;
the content of the asbestos fiber in the anti-carsickness fragrant material is tested according to the test method of Q/JLY J7110808B-2016, and the result shows that the requirement that the parts in Q/JL J160001-2020 are forbidden to use the asbestos fiber is met;
verifying the toxicity of the carsickness-preventing fragrance material according to the specification of an SN _ T4030-2014 fragrance cosmetic acute inhalation toxicity test; the result shows that the carsickness-preventing fragrance material provided by the invention belongs to a non-toxic grade.
In conclusion, the carsickness prevention essential oil, the carsickness prevention fragrance material and the fragrance generator provided by the invention adopt the traditional Chinese medicine components without stimulation and side effects as raw materials, meet the requirements of no toxicity and no harm to human bodies, and have excellent safety and carsickness prevention effects. The carsickness-preventing essential oil is solidified into the fragrance solid by adopting the carrier matrix, so that the fragrance solid is convenient to store and use, the carsickness-preventing fragrance material can relieve carsickness of drivers and passengers, and the defect that the driving safety of the drivers is influenced by common carsickness medicines is overcome.
The embodiments of the present invention have been described above. However, the present invention is not limited to the above embodiment. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The carsickness prevention essential oil is characterized by comprising the following raw materials in parts by weight: 40-50% of peppermint oil, 20-30% of ginger oil, 10-20% of citrus extract, 3-7% of angelica extract, 3-7% of perilla extract and 3-7% of patchouli oil.
2. The carsickness prevention essential oil as claimed in claim 1, wherein the angelica sinensis extract is prepared according to a preparation process comprising the following steps: soaking radix Angelicae sinensis in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain radix Angelicae sinensis extractive solution; wherein the concentration of the angelica sinensis extracting solution is controlled to meet the following requirements: the ratio of the volume of the Chinese angelica extracting solution to the mass of the Chinese angelica raw material is 3-7 mL: 1g of the total weight of the composition.
3. The carsickness prevention essential oil as claimed in claim 1, wherein the perilla herb extract is prepared by a preparation process comprising the following steps: soaking the perilla raw material in an ethanol solution for 0.3 to 0.7 hours, decocting, filtering, and concentrating the obtained filtrate to obtain the perilla extracting solution; wherein, the concentration of the perilla extract is controlled to meet the following conditions: the ratio of the volume of the perilla extracting solution to the mass of the perilla raw material is 3-6 mL: 1g of the total weight of the composition.
4. The carsickness prevention essential oil as claimed in claim 1, wherein the citrus extract is prepared according to a preparation process comprising the following steps: soaking pericarpium Citri Tangerinae in water for 0.5-1.5 hr, decocting, filtering, and concentrating the filtrate to obtain the citrus extract; wherein, the concentration of the citrus extract is controlled to meet the following conditions: the ratio of the volume of the citrus extract to the mass of the dried orange peel raw material is 3mL-6 mL: 1g of a compound; and/or the presence of a gas in the gas,
the peppermint oil is prepared according to the preparation process comprising the following steps: soaking a mint leaf raw material in a soluble salt solution, distilling to obtain a distillate, removing a water phase in the distillate to obtain the mint oil, wherein the ratio of the mass of the mint leaf raw material to the volume of the soluble salt solution is 1: 9-13; and/or the presence of a gas in the gas,
the ginger oil is prepared according to a preparation process comprising the following steps: drying a ginger raw material, grinding the dried ginger raw material into ginger powder, mixing the ginger powder with diethyl ether, treating the mixture at 45-50 ℃ for 30min, then filtering the mixture, filtering the obtained first filtrate under reduced pressure, and collecting a second filtrate to obtain the ginger oil, wherein the ratio of the mass of the ginger powder to the volume of the diethyl ether is 1: 2-5; and/or the presence of a gas in the gas,
the patchouli oil is prepared by the preparation process comprising the following steps: drying and grinding agastache rugosus raw materials into agastache rugosus powder, adding water to distill to obtain distillate, and removing a water phase in the distillate to obtain the agastache rugosus oil, wherein the mass ratio of the agastache rugosus powder to the water is 1: 3-7.
5. An anti-carsickness fragrance material comprising a carrier matrix and the anti-carsickness essential oil of any one of claims 1-4, wherein the carrier matrix comprises at least one of a gel, an ethylene vinyl acetate copolymer, a ceramic, and gypsum.
6. A fragrance generator, comprising:
a fragrance container for containing the anti-carsickness fragrance material of claim 5; the fragrance container is provided with a fragrance outlet for emitting fragrance generated by the carsickness-preventing fragrance material;
and the chip is connected with the fragrance container and is used for obtaining the residual amount of the anti-carsickness fragrance material in the fragrance container.
7. The fragrance generator of claim 6, wherein the number of fragrance containers is at least two, each fragrance container has an independent fragrance outlet, and each fragrance container outlet is provided with a switch.
8. The fragrance generator according to claim 6 or 7, further comprising at least two fragrance outlets, each fragrance container having an independent fragrance outlet, the fragrance outlet of each fragrance container being in communication with the fragrance outlet.
9. The fragrance generator of claim 6, further comprising a fan coupled to the fragrance container for blowing out the fragrance created by the anti-carsickness fragrance material in the fragrance container.
10. The fragrance generator of claim 8, wherein the number of fragrance containers is three.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210036839.5A CN114366728A (en) | 2022-01-13 | 2022-01-13 | Carsickness-preventing essential oil, carsickness-preventing fragrance material and fragrance generator |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210036839.5A CN114366728A (en) | 2022-01-13 | 2022-01-13 | Carsickness-preventing essential oil, carsickness-preventing fragrance material and fragrance generator |
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| CN114366728A true CN114366728A (en) | 2022-04-19 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210036839.5A Pending CN114366728A (en) | 2022-01-13 | 2022-01-13 | Carsickness-preventing essential oil, carsickness-preventing fragrance material and fragrance generator |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115040625A (en) * | 2022-06-17 | 2022-09-13 | 浙江芳香生物科技有限公司 | Essential oil for relieving carsickness and preparation method and use method thereof |
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| CN107158343A (en) * | 2017-05-31 | 2017-09-15 | 皖南医学院 | A kind of carsickness-proof essential oil containing Chinese medical extract and preparation method thereof |
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