CN114306899A - 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 - Google Patents

包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Download PDF

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Publication number
CN114306899A
CN114306899A CN202111310044.0A CN202111310044A CN114306899A CN 114306899 A CN114306899 A CN 114306899A CN 202111310044 A CN202111310044 A CN 202111310044A CN 114306899 A CN114306899 A CN 114306899A
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China
Prior art keywords
drug
lumen
silicone
elongated body
matrix system
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Pending
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CN202111310044.0A
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English (en)
Chinese (zh)
Inventor
李喜真
卡伦·丹尼尔
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Janssen Biotech Inc
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Taris Biomedical Inc
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Publication of CN114306899A publication Critical patent/CN114306899A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0009—Making of catheters or other medical or surgical tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216—Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00—Methods of manufacture, assembly or production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1078—Urinary tract
    • A61M2210/1085—Bladder

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN202111310044.0A 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法 Pending CN114306899A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462017775P 2014-06-26 2014-06-26
US62/017775 2014-06-26
CN201580033832.6A CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法
PCT/US2015/037887 WO2015200752A1 (en) 2014-06-26 2015-06-26 Intravesical drug delivery devices and methods including elastic polymer-drug matrix systems

Related Parent Applications (1)

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CN201580033832.6A Division CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

Publications (1)

Publication Number Publication Date
CN114306899A true CN114306899A (zh) 2022-04-12

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CN202111310044.0A Pending CN114306899A (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法
CN201580033832.6A Active CN106456951B (zh) 2014-06-26 2015-06-26 包含弹性聚合物-药物基质系统的膀胱内药物递送装置及方法

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Country Status (9)

Country Link
US (3) US10737078B2 (https=)
EP (3) EP3160442B1 (https=)
JP (3) JP6856380B2 (https=)
KR (4) KR102486216B1 (https=)
CN (2) CN114306899A (https=)
AU (4) AU2015279674B2 (https=)
DK (1) DK3160442T3 (https=)
ES (2) ES2728504T3 (https=)
WO (1) WO2015200752A1 (https=)

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CN115120854A (zh) * 2022-07-04 2022-09-30 奥格生物技术（六安）有限公司 前列腺自然直接给药法

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US20150250717A1 (en) 2014-03-06 2015-09-10 Taris Biomedical Llc Drug delivery systems and methods for treatment of bladder cancer with gemcitabine
WO2016176444A1 (en) * 2015-04-29 2016-11-03 Northwestern University 3d printing of biomedical implants
US11185670B2 (en) 2016-01-26 2021-11-30 Taris Biomedical Llc Multi-lumen drug delivery devices
CN118453872A (zh) 2016-05-06 2024-08-09 塔里斯生物医药公司 治疗下尿路尿道上皮癌的方法
SG10201913998YA (en) 2017-07-25 2020-03-30 Taris Biomedical Llc Methods of treating tumor metastasis
IL302714B1 (en) 2017-11-08 2026-01-01 Taris Biomedical Llc Methods for treating and maintaining bladder cancer using gemcitabine
WO2019232291A1 (en) * 2018-05-31 2019-12-05 Massachusetts Institute Of Technology Drug delivery articles for gram-level dosing
CN112839653A (zh) 2018-08-01 2021-05-25 塔里斯生物医药公司 使用曲司氯铵治疗膀胱过度活动症的方法
KR102941301B1 (ko) * 2018-11-09 2026-03-18 타리스 바이오메디컬 엘엘씨 상부 요로로의 국소 약물 전달을 위한 약물 전달 장치 및 시스템
WO2022067197A1 (en) * 2020-09-28 2022-03-31 The Regents Of The University Of California Drug implants containing apalutamide and methods of use thereof
EP4710986A2 (en) 2021-12-21 2026-03-18 TARIS Biomedical LLC Urinary placement catheter for intravesical devices
WO2024020105A1 (en) * 2022-07-20 2024-01-25 The Regents Of The University Of California Drug implants containing darolutamide and methods of use thereof
WO2024092159A1 (en) 2022-10-28 2024-05-02 Taris Biomedical Llc Methods of treating bladder cancer with gemcitabine
KR20250168664A (ko) 2023-04-10 2025-12-02 타리스 바이오메디컬 엘엘씨 바실루스 칼메트-구에린 요법에 무반응성인 고위험 근육 비침습성 방광암을 치료하는 방법에 사용하기 위한 젬시타빈
TW202532086A (zh) 2023-10-02 2025-08-16 美商塔里斯生物醫學有限責任公司 治療對卡介苗療法無反應之高風險非肌肉侵襲性膀胱癌之方法

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US5062829A (en) * 1989-03-17 1991-11-05 Carter Holt Harvey Plastic Products Group Limited Relates to devices for administering a substance such as a drug or chemical or the like
US20060052757A1 (en) * 1996-06-04 2006-03-09 Vance Products Incorporated, D/B/A Cook Urological Incorporated Implantable medical device with analgesic or anesthetic
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US20090149833A1 (en) * 2007-12-11 2009-06-11 Massachusetts Institute Of Technology Implantable Drug Delivery Device and Methods for Treatment of the Bladder and Other Body Vesicles or Lumens
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CN102596174A (zh) * 2009-09-10 2012-07-18 塔里斯生物医药公司 用于受控的药物递送的可植入装置
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115120854A (zh) * 2022-07-04 2022-09-30 奥格生物技术（六安）有限公司 前列腺自然直接给药法
CN115120854B (zh) * 2022-07-04 2023-10-13 奥格生物技术（六安）有限公司 前列腺自然直接给药装置

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AU2015279674A1 (en) 2017-01-12
AU2015279674B2 (en) 2020-07-23
AU2022204523B2 (en) 2024-05-16
JP2022022292A (ja) 2022-02-03
AU2024204468B2 (en) 2026-02-26
ES2728504T3 (es) 2019-10-25
AU2020250209A1 (en) 2020-11-05
US20200368508A1 (en) 2020-11-26
KR102391761B1 (ko) 2022-04-27
AU2024204468A1 (en) 2024-07-18
CN106456951B (zh) 2021-11-05
KR20170026465A (ko) 2017-03-08
JP7005668B2 (ja) 2022-01-21
US11904123B2 (en) 2024-02-20
KR20230142816A (ko) 2023-10-11
EP3160442A1 (en) 2017-05-03
EP4173615A3 (en) 2023-07-19
KR20220061254A (ko) 2022-05-12
KR102486216B1 (ko) 2023-01-09
JP2017524421A (ja) 2017-08-31
US12239807B2 (en) 2025-03-04
EP4173615A2 (en) 2023-05-03
ES2940478T3 (es) 2023-05-08
JP2020110615A (ja) 2020-07-27
US20170165460A1 (en) 2017-06-15
JP6856380B2 (ja) 2021-04-07
AU2022204523A1 (en) 2022-07-21
US20200368509A1 (en) 2020-11-26
EP3517099B1 (en) 2022-12-28
WO2015200752A8 (en) 2016-08-11
AU2020250209B2 (en) 2022-07-14
US10737078B2 (en) 2020-08-11
EP3160442B1 (en) 2019-03-06
CN106456951A (zh) 2017-02-22
KR20220061253A (ko) 2022-05-12
WO2015200752A1 (en) 2015-12-30
DK3160442T3 (da) 2019-06-11
EP3517099A1 (en) 2019-07-31

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