CN114223898A - Formula and preparation process of active ingredients of oral product for improving sleep - Google Patents
Formula and preparation process of active ingredients of oral product for improving sleep Download PDFInfo
- Publication number
- CN114223898A CN114223898A CN202111503064.XA CN202111503064A CN114223898A CN 114223898 A CN114223898 A CN 114223898A CN 202111503064 A CN202111503064 A CN 202111503064A CN 114223898 A CN114223898 A CN 114223898A
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- China
- Prior art keywords
- parts
- oral product
- improving sleep
- formula
- mulberry
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- Pending
Links
- 239000013588 oral product Substances 0.000 title claims abstract description 18
- 229940023486 oral product Drugs 0.000 title claims abstract description 18
- 239000004480 active ingredient Substances 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 238000009472 formulation Methods 0.000 title claims description 4
- 240000000249 Morus alba Species 0.000 claims abstract description 10
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 10
- 235000011925 Passiflora alata Nutrition 0.000 claims abstract description 10
- 235000000370 Passiflora edulis Nutrition 0.000 claims abstract description 10
- 235000011922 Passiflora incarnata Nutrition 0.000 claims abstract description 10
- 240000002690 Passiflora mixta Species 0.000 claims abstract description 10
- 235000013750 Passiflora mixta Nutrition 0.000 claims abstract description 10
- 235000013731 Passiflora van volxemii Nutrition 0.000 claims abstract description 10
- 241000408747 Lepomis gibbosus Species 0.000 claims abstract description 8
- 244000197580 Poria cocos Species 0.000 claims abstract description 8
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 8
- 244000269722 Thea sinensis Species 0.000 claims abstract description 8
- 244000126014 Valeriana officinalis Species 0.000 claims abstract description 8
- 235000013832 Valeriana officinalis Nutrition 0.000 claims abstract description 8
- 235000009569 green tea Nutrition 0.000 claims abstract description 8
- 235000020236 pumpkin seed Nutrition 0.000 claims abstract description 8
- 235000016788 valerian Nutrition 0.000 claims abstract description 8
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 3
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 3
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 3
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 108090000790 Enzymes Proteins 0.000 claims description 19
- 102000004190 Enzymes Human genes 0.000 claims description 19
- 229940088598 enzyme Drugs 0.000 claims description 19
- 239000000706 filtrate Substances 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 8
- 108010059892 Cellulase Proteins 0.000 claims description 7
- 229940106157 cellulase Drugs 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 108010059820 Polygalacturonase Proteins 0.000 claims description 6
- 108010093305 exopolygalacturonase Proteins 0.000 claims description 6
- 235000017784 Mespilus germanica Nutrition 0.000 claims description 5
- 244000182216 Mimusops elengi Species 0.000 claims description 5
- 235000000560 Mimusops elengi Nutrition 0.000 claims description 5
- 235000007837 Vangueria infausta Nutrition 0.000 claims description 5
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 238000000227 grinding Methods 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 238000006460 hydrolysis reaction Methods 0.000 claims description 5
- 238000001694 spray drying Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 6
- 235000013305 food Nutrition 0.000 abstract description 6
- 231100000957 no side effect Toxicity 0.000 abstract description 4
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 4
- 239000000047 product Substances 0.000 abstract description 3
- 239000002131 composite material Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 5
- 241000196324 Embryophyta Species 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 210000002421 cell wall Anatomy 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 235000001188 Peltandra virginica Nutrition 0.000 description 1
- 108091005804 Peptidases Proteins 0.000 description 1
- 206010062519 Poor quality sleep Diseases 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
A formula of an active component of an oral product for improving sleep and a preparation process thereof, which relate to the technical field of health care products; the composite material consists of the following raw materials in parts by weight: 20-30 parts of passion flower, 15-20 parts of mulberry, 25-35 parts of pumpkin seed, 30-40 parts of valerian root, 35-45 parts of poria cocos, 13-20 parts of green tea, 43-50 parts of wolfberry and 25-35 parts of spina date seed. The formula and the preparation process of the active ingredient of the oral product for improving sleep provided by the invention adopt food formula, are homologous in medicine and food, can be taken for a long time, have no side effect or dependence, can improve sleep, and can achieve the effect which cannot be achieved by traditional Chinese medicines.
Description
Technical Field
The invention relates to the technical field of health products, in particular to a formula and a preparation process of an active ingredient of an oral product for improving sleep.
Background
The traditional sleep products mostly adopt the compound combination of Chinese herbal medicines as the main material, the traditional Chinese medicines have strong curative effect, the effect is prominent when the medicines are correctly taken, and obvious side effects are easy to appear when the medicines are not properly taken, so that the traditional Chinese medicine not only can treat the poor sleep, but also can cause great harm to the body.
Disclosure of Invention
The invention aims to provide a formula and a preparation process of an active ingredient of an oral product, which can be taken for a long time and has no side effect or dependence and can improve sleep aiming at the defects and the defects of the prior art.
In order to achieve the purpose, the invention adopts the technical scheme that: the formula of an oral product active component for improving sleep comprises the following raw materials in parts by weight: 20-30 parts of passion flower, 15-20 parts of mulberry, 25-35 parts of pumpkin seed, 30-40 parts of valerian root, 35-45 parts of poria cocos, 13-20 parts of green tea, 43-50 parts of wolfberry and 25-35 parts of spina date seed.
Furthermore, the weight portion of the passion flower is 25 g.
Further, the mulberry accounts for 15g in parts by weight.
A process for preparing an active ingredient of an oral product for improving sleep, comprising the steps of:
1. taking 20-30 parts of dry passion flower, 15-20 parts of mulberry, 25-35 parts of pumpkin seed, 30-40 parts of valerian root, 35-45 parts of poria cocos, 13-20 parts of green tea, 43-50 parts of medlar and 25-35 parts of spina date seed, and grinding the materials into fine powder by a grinder;
2. adding 0.5-1% of mixed aqueous solution of pectinase and cellulase with the weight of 1: 1-1: 3 into the fine powder obtained in the step 1, carrying out enzyme hydrolysis reaction at 40-60 ℃ for 1-8 hours, and obtaining enzyme treatment liquid layered up and down after the reaction is finished;
3. and fully mixing the enzyme treatment liquid, adding 6-10 times of water, heating to 50-70 ℃, stirring and extracting for 60-80 minutes, filtering to obtain a filtrate, extracting the filter residue for 1-2 times by the same method, combining the filtered filtrates, concentrating the filtrate to a thick paste with the relative density of 1.1-1.2, and spray-drying to obtain the enzyme preparation with the water content of 3-5%.
The invention has the following beneficial effects: the formula and the preparation process of the active ingredient of the oral product for improving sleep provided by the invention adopt food formula, are homologous in medicine and food, can be taken for a long time, have no side effect or dependence, can improve sleep, and can achieve the effect which cannot be achieved by traditional Chinese medicines.
Detailed Description
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the above technical solutions will be described in detail below.
Example 1
A process for preparing an active ingredient of an oral product for improving sleep, comprising the steps of:
1. grinding 20 parts of dry passion flower, 15 parts of mulberry, 25 parts of pumpkin seed, 30 parts of valerian root, 35 parts of poria cocos, 13 parts of green tea, 43 parts of medlar and 25 parts of spina date seed into fine powder by a grinder;
2. adding 0.5-1% of mixed aqueous solution of pectinase and cellulase with the weight of 1: 2 into the fine powder obtained in the step 1, carrying out enzyme hydrolysis reaction at 40 ℃ for 5 hours, and obtaining enzyme treatment liquid layered up and down after the reaction is finished;
3. mixing the enzyme treated solution, adding 8 times of water, heating to 70 deg.C, stirring and extracting for 60 min, filtering to obtain filtrate, extracting the residue with the same method for 2 times, mixing the filtrates, concentrating the filtrate to obtain soft extract with relative density of 1.1, and spray drying to water content of 3%.
Example 2
A process for preparing an active ingredient of an oral product for improving sleep, comprising the steps of:
1. taking 25g of dry passion flower, 15g of mulberry, 35g of pumpkin seed, 30g of valerian root, 40g of tuckahoe, 15g of green tea, 48g of medlar and 25g of spina date seed, and grinding into fine powder by a grinder;
2. adding 1% pectinase and cellulase mixed aqueous solution with the weight of 1: 2 into the fine powder obtained in the step 1, carrying out enzyme hydrolysis reaction at 50 ℃ for 6 hours, and obtaining enzyme treatment liquid with upper and lower layers after the reaction is finished;
3. mixing the enzyme treated solution, adding 8 times of water, heating to 60 deg.C, stirring and extracting for 70 min, filtering to obtain filtrate, extracting the residue with the same method for 2 times, mixing the filtrates, concentrating the filtrate to obtain soft extract with relative density of 1.2, and spray drying to water content of 4%.
Example 3
A process for preparing an active ingredient of an oral product for improving sleep, comprising the steps of:
1. grinding 30 parts of dry passion flower, 20 parts of mulberry, 35 parts of pumpkin seed, 40 parts of valerian root, 45 parts of poria cocos, 20 parts of green tea, 50 parts of medlar and 35 parts of spina date seed into fine powder by a grinder;
2. adding 0.5 percent of pectinase and cellulase mixed aqueous solution with the weight of 1: 2 into the fine powder obtained in the step 1, carrying out enzyme hydrolysis reaction at the temperature of 50 ℃ for 6 hours, and obtaining enzyme treatment liquid with upper and lower layers after the reaction is finished;
3. mixing the enzyme treated solution, adding 8 times of water, heating to 60 deg.C, stirring and extracting for 70 min, filtering to obtain filtrate, extracting the residue with the same method for 2 times, mixing the filtrates, concentrating the filtrate to obtain soft extract with relative density of 1.1, and spray drying to water content of 4%.
In the present embodiment, an enzyme extraction method is used in combination with a solvent extraction method: the cell wall of natural plant is made of cellulose, the effective components of plant are often wrapped in the cell wall, and the enzyme extraction method is a method for destroying the cell wall of plant by using cellulase, pectinase or protease (mainly cellulase) to promote the maximum dissolution and separation of the effective components of plant.
The beneficial effects produced by the specific implementation mode are as follows: according to the formula and the preparation process of the active ingredient of the oral product for improving sleep, a food formula is adopted, the medicine and food are homologous, the oral product can be taken for a long time, no side effect or dependence is caused, the sleep can be improved, and the effect which cannot be achieved by traditional Chinese medicines can be achieved.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (4)
1. The formula of the active ingredients of the oral product for improving sleep is characterized by comprising the following raw materials in parts by weight: 20-30 parts of passion flower, 15-20 parts of mulberry, 25-35 parts of pumpkin seed, 30-40 parts of valerian root, 35-45 parts of poria cocos, 13-20 parts of green tea, 43-50 parts of wolfberry and 25-35 parts of spina date seed.
2. A preparation process of an active ingredient of an oral product for improving sleep is characterized by comprising the following steps:
(1) taking 20-30 parts of dry passion flower, 15-20 parts of mulberry, 25-35 parts of pumpkin seed, 30-40 parts of valerian root, 35-45 parts of poria cocos, 13-20 parts of green tea, 43-50 parts of medlar and 25-35 parts of spina date seed, and grinding the materials into fine powder by a grinder;
(2) adding 0.5-1% of mixed aqueous solution of pectinase and cellulase in a weight ratio of 1: 1-1: 3 into the fine powder obtained in the step (1), performing enzyme hydrolysis reaction at 40-60 ℃ for 1-8 hours, and obtaining enzyme treatment liquid layered up and down after the reaction is finished;
(3) fully mixing the enzyme treatment liquid, adding 6-10 times of water, heating to 50-70 ℃, stirring and extracting for 60-80 minutes, filtering to obtain a filtrate, extracting the filter residue for 1-2 times by the same method, combining the filtered filtrates, concentrating the filtrate to a thick paste with the relative density of 1.1-1.2, and spray-drying to obtain the enzyme preparation with the water content of 3-5%.
3. The formulation of active ingredients of an oral product for improving sleep as claimed in claim 1, wherein: the weight portion of the passion flower is 25 g.
4. The formulation of active ingredients of an oral product for improving sleep as claimed in claim 1, wherein: the mulberry is 15g in parts by weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111503064.XA CN114223898A (en) | 2021-12-09 | 2021-12-09 | Formula and preparation process of active ingredients of oral product for improving sleep |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111503064.XA CN114223898A (en) | 2021-12-09 | 2021-12-09 | Formula and preparation process of active ingredients of oral product for improving sleep |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114223898A true CN114223898A (en) | 2022-03-25 |
Family
ID=80754470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111503064.XA Pending CN114223898A (en) | 2021-12-09 | 2021-12-09 | Formula and preparation process of active ingredients of oral product for improving sleep |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114223898A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784611A (en) * | 2014-01-23 | 2014-05-14 | 云南白药天颐茶品有限公司 | Composition capable of improving sleep and relieving pressure and application thereof |
| CN109893555A (en) * | 2019-02-15 | 2019-06-18 | 台湾中油股份有限公司 | A kind of pumpkin seeds extract and preparation method thereof and purposes |
| CN110507754A (en) * | 2019-10-15 | 2019-11-29 | 安徽省本草国药饮片有限公司 | A kind of semen ziziphi spinosae sleeping tea and preparation method thereof |
-
2021
- 2021-12-09 CN CN202111503064.XA patent/CN114223898A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103784611A (en) * | 2014-01-23 | 2014-05-14 | 云南白药天颐茶品有限公司 | Composition capable of improving sleep and relieving pressure and application thereof |
| CN109893555A (en) * | 2019-02-15 | 2019-06-18 | 台湾中油股份有限公司 | A kind of pumpkin seeds extract and preparation method thereof and purposes |
| CN110507754A (en) * | 2019-10-15 | 2019-11-29 | 安徽省本草国药饮片有限公司 | A kind of semen ziziphi spinosae sleeping tea and preparation method thereof |
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Application publication date: 20220325 |
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