CN114126585A - 包含氯己定或其衍生物的抗菌耐久性得以改善的水溶性消毒组合物及包含其的纤维型消毒剂 - Google Patents
包含氯己定或其衍生物的抗菌耐久性得以改善的水溶性消毒组合物及包含其的纤维型消毒剂 Download PDFInfo
- Publication number
- CN114126585A CN114126585A CN202080052523.4A CN202080052523A CN114126585A CN 114126585 A CN114126585 A CN 114126585A CN 202080052523 A CN202080052523 A CN 202080052523A CN 114126585 A CN114126585 A CN 114126585A
- Authority
- CN
- China
- Prior art keywords
- water
- chlorhexidine
- disinfecting composition
- derivative
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 99
- 230000000249 desinfective effect Effects 0.000 title claims abstract description 82
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title claims abstract description 63
- 229960003260 chlorhexidine Drugs 0.000 title claims abstract description 62
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 40
- 239000000645 desinfectant Substances 0.000 title claims abstract description 39
- 239000000835 fiber Substances 0.000 title claims abstract description 32
- -1 fatty acid ester Chemical class 0.000 claims abstract description 47
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 36
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims abstract description 35
- 229910052710 silicon Inorganic materials 0.000 claims abstract description 35
- 239000010703 silicon Substances 0.000 claims abstract description 35
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 27
- 239000000194 fatty acid Substances 0.000 claims abstract description 27
- 229930195729 fatty acid Natural products 0.000 claims abstract description 27
- 230000001186 cumulative effect Effects 0.000 claims abstract description 26
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 25
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 25
- 239000000463 material Substances 0.000 claims description 19
- 239000002245 particle Substances 0.000 claims description 19
- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims description 18
- 229940083037 simethicone Drugs 0.000 claims description 18
- 239000004745 nonwoven fabric Substances 0.000 claims description 14
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 13
- 230000007774 longterm Effects 0.000 claims description 11
- 239000003381 stabilizer Substances 0.000 claims description 9
- 229920000742 Cotton Polymers 0.000 claims description 7
- 238000009826 distribution Methods 0.000 claims description 7
- 235000011187 glycerol Nutrition 0.000 claims description 7
- 230000000845 anti-microbial effect Effects 0.000 claims description 6
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 5
- 229920000297 Rayon Polymers 0.000 claims description 5
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 5
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 5
- 239000002964 rayon Substances 0.000 claims description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 4
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 4
- 241001330002 Bambuseae Species 0.000 claims description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 4
- 239000004743 Polypropylene Substances 0.000 claims description 4
- 239000011425 bamboo Substances 0.000 claims description 4
- 229920000728 polyester Polymers 0.000 claims description 4
- 229920001155 polypropylene Polymers 0.000 claims description 4
- WJLVQTJZDCGNJN-UHFFFAOYSA-N Chlorhexidine hydrochloride Chemical compound Cl.Cl.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WJLVQTJZDCGNJN-UHFFFAOYSA-N 0.000 claims description 3
- 229920001131 Pulp (paper) Polymers 0.000 claims description 3
- 239000002390 adhesive tape Substances 0.000 claims description 3
- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical compound CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 claims description 3
- 229960001884 chlorhexidine diacetate Drugs 0.000 claims description 3
- 229940071160 cocoate Drugs 0.000 claims description 3
- 239000004744 fabric Substances 0.000 claims description 3
- 230000002439 hemostatic effect Effects 0.000 claims description 3
- 239000002759 woven fabric Substances 0.000 claims description 2
- JNAYPSWVMNJOPQ-UHFFFAOYSA-N 2,3-bis(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C JNAYPSWVMNJOPQ-UHFFFAOYSA-N 0.000 claims 1
- 239000008346 aqueous phase Substances 0.000 abstract description 8
- 238000013268 sustained release Methods 0.000 abstract description 6
- 239000012730 sustained-release form Substances 0.000 abstract description 6
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- 230000000052 comparative effect Effects 0.000 description 15
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 14
- 239000000839 emulsion Substances 0.000 description 12
- 239000000126 substance Substances 0.000 description 10
- 229940074047 glyceryl cocoate Drugs 0.000 description 8
- 239000006185 dispersion Substances 0.000 description 7
- 239000002904 solvent Substances 0.000 description 7
- 238000001179 sorption measurement Methods 0.000 description 7
- 238000004659 sterilization and disinfection Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 5
- 238000011156 evaluation Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 231100000683 possible toxicity Toxicity 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 239000003021 water soluble solvent Substances 0.000 description 4
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 239000004205 dimethyl polysiloxane Substances 0.000 description 3
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 229940050410 gluconate Drugs 0.000 description 3
- 238000004811 liquid chromatography Methods 0.000 description 3
- 239000003002 pH adjusting agent Substances 0.000 description 3
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 3
- 229920001223 polyethylene glycol Polymers 0.000 description 3
- 229920000223 polyglycerol Polymers 0.000 description 3
- 239000004094 surface-active agent Substances 0.000 description 3
- DJXPNUIRGNRCPQ-UHFFFAOYSA-N 2-[2,3-bis[2-(16-methylheptadecanoyloxy)ethoxy]propoxy]ethyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCCOCC(COCCOC(=O)CCCCCCCCCCCCCCC(C)C)OCCOC(=O)CCCCCCCCCCCCCCC(C)C DJXPNUIRGNRCPQ-UHFFFAOYSA-N 0.000 description 2
- 229920001213 Polysorbate 20 Polymers 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 229940075507 glyceryl monostearate Drugs 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000001788 mono and diglycerides of fatty acids Substances 0.000 description 2
- 229940086539 peg-7 glyceryl cocoate Drugs 0.000 description 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 2
- 229940068977 polysorbate 20 Drugs 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 230000002459 sustained effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- MMINFSMURORWKH-UHFFFAOYSA-N 3,6-dioxabicyclo[6.2.2]dodeca-1(10),8,11-triene-2,7-dione Chemical compound O=C1OCCOC(=O)C2=CC=C1C=C2 MMINFSMURORWKH-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- RDOFJDLLWVCMRU-UHFFFAOYSA-N Diisobutyl adipate Chemical compound CC(C)COC(=O)CCCCC(=O)OCC(C)C RDOFJDLLWVCMRU-UHFFFAOYSA-N 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 241000186366 Mycobacterium bovis Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920001219 Polysorbate 40 Polymers 0.000 description 1
- 229920001214 Polysorbate 60 Polymers 0.000 description 1
- 229920002642 Polysorbate 65 Polymers 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 150000004287 bisbiguanides Chemical class 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 229940031769 diisobutyl adipate Drugs 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- LRCFXGAMWKDGLA-UHFFFAOYSA-N dioxosilane;hydrate Chemical compound O.O=[Si]=O LRCFXGAMWKDGLA-UHFFFAOYSA-N 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 125000003827 glycol group Chemical group 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 description 1
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 description 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
- 239000001816 polyoxyethylene sorbitan tristearate Substances 0.000 description 1
- 235000010988 polyoxyethylene sorbitan tristearate Nutrition 0.000 description 1
- 229940101027 polysorbate 40 Drugs 0.000 description 1
- 229940113124 polysorbate 60 Drugs 0.000 description 1
- 229940099511 polysorbate 65 Drugs 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 229940068968 polysorbate 80 Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 229960004029 silicic acid Drugs 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (14)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020190088288A KR102340804B1 (ko) | 2019-07-22 | 2019-07-22 | 클로르헥시딘 또는 이의 유도체를 포함하는 항균 지속성이 개선된 수용성 소독용 조성물 및 이를 포함하는 섬유형 소독제 |
KR10-2019-0088288 | 2019-07-22 | ||
PCT/KR2020/008139 WO2021015426A1 (ko) | 2019-07-22 | 2020-06-24 | 클로르헥시딘 또는 이의 유도체를 포함하는 항균 지속성이 개선된 수용성 소독용 조성물 및 이를 포함하는 섬유형 소독제 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN114126585A true CN114126585A (zh) | 2022-03-01 |
CN114126585B CN114126585B (zh) | 2024-04-09 |
Family
ID=74193048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202080052523.4A Active CN114126585B (zh) | 2019-07-22 | 2020-06-24 | 包含氯己定或其衍生物的抗菌耐久性得以改善的水溶性消毒组合物及包含其的纤维型消毒剂 |
Country Status (4)
Country | Link |
---|---|
US (1) | US20220249407A1 (zh) |
KR (1) | KR102340804B1 (zh) |
CN (1) | CN114126585B (zh) |
WO (1) | WO2021015426A1 (zh) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070025948A1 (en) * | 2003-04-22 | 2007-02-01 | Dainippon Sumitomo Pharma Co. Ltd | Dilution-type sterilizer composition |
CN101384253A (zh) * | 2006-02-15 | 2009-03-11 | 丸石制药株式会社 | 消毒用软膏剂 |
WO2009089346A2 (en) * | 2008-01-08 | 2009-07-16 | Quick-Med Technologies, Inc. | Disinfectant alcohol-soluble quaternary ammonium polymers |
CN101720786A (zh) * | 2009-11-30 | 2010-06-09 | 时敏秀 | 一种临床手术器械消毒剂 |
CN101959493A (zh) * | 2008-03-07 | 2011-01-26 | 金伯利-克拉克环球有限公司 | 手部保湿卫生洗涤剂 |
CN104622716A (zh) * | 2015-02-27 | 2015-05-20 | 李航 | 一种不含酒精的长效抗菌去污医用护理湿巾及消毒液 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2424003A1 (en) * | 2003-03-28 | 2004-09-28 | Austin & Repatriation Medical Centre | Anti-microbial topical composition comprising alcohol and chlorhexidine salt |
CN102149392B (zh) * | 2008-08-15 | 2016-06-01 | 艾克斯特瑞姆实验室公司 | 温和无刺激无醇的皮肤消毒剂 |
US8603550B1 (en) * | 2013-05-15 | 2013-12-10 | Normajean Fusco | Compositions for topical treatment |
CN107530468A (zh) * | 2015-03-10 | 2018-01-02 | 科发龙技术公司 | 局部减少微生物皮肤菌群的方法 |
-
2019
- 2019-07-22 KR KR1020190088288A patent/KR102340804B1/ko active IP Right Grant
-
2020
- 2020-06-24 US US17/629,197 patent/US20220249407A1/en active Pending
- 2020-06-24 WO PCT/KR2020/008139 patent/WO2021015426A1/ko active Application Filing
- 2020-06-24 CN CN202080052523.4A patent/CN114126585B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070025948A1 (en) * | 2003-04-22 | 2007-02-01 | Dainippon Sumitomo Pharma Co. Ltd | Dilution-type sterilizer composition |
CN101384253A (zh) * | 2006-02-15 | 2009-03-11 | 丸石制药株式会社 | 消毒用软膏剂 |
WO2009089346A2 (en) * | 2008-01-08 | 2009-07-16 | Quick-Med Technologies, Inc. | Disinfectant alcohol-soluble quaternary ammonium polymers |
CN101959493A (zh) * | 2008-03-07 | 2011-01-26 | 金伯利-克拉克环球有限公司 | 手部保湿卫生洗涤剂 |
CN101720786A (zh) * | 2009-11-30 | 2010-06-09 | 时敏秀 | 一种临床手术器械消毒剂 |
CN104622716A (zh) * | 2015-02-27 | 2015-05-20 | 李航 | 一种不含酒精的长效抗菌去污医用护理湿巾及消毒液 |
Also Published As
Publication number | Publication date |
---|---|
KR102340804B1 (ko) | 2021-12-17 |
US20220249407A1 (en) | 2022-08-11 |
WO2021015426A1 (ko) | 2021-01-28 |
CN114126585B (zh) | 2024-04-09 |
KR20210011187A (ko) | 2021-02-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TWI301068B (en) | Medical dressing containing antimicrobial agent | |
JP3974203B2 (ja) | 殺菌組成物 | |
EP1868665B1 (en) | Silver coatings and methods of manufacture | |
EP1755569B1 (de) | Wundauflage | |
KR20120104156A (ko) | 항미생물제를 포함하는 입자 | |
DE69018684T2 (de) | Antimikrobielle Kunststoffmaterialien mit Breitbandwirkung. | |
JP2003500554A (ja) | 抗微生物性物品 | |
BRPI0622130B1 (pt) | artigos absorventes compreendendo um sal orgânico de zinco e um agente antibacteriano ou cloreto de metal alcalino ou cloreto de metal alcalino terroso | |
CN111418607B (zh) | 一种复合纳米银抗病毒剂及其制备方法和应用 | |
WO2007115635A1 (de) | Biguanidhaltige liposomen | |
EP3430181B1 (en) | Processes for deposition of elemental silver onto a substrate | |
KR20170077173A (ko) | 산화아연 함유 셀룰로즈 섬유를 함유하는 액체-함침된 부직포 | |
US20130149367A1 (en) | Processes for producing antitoxic fibers and fabrics | |
CN114126585B (zh) | 包含氯己定或其衍生物的抗菌耐久性得以改善的水溶性消毒组合物及包含其的纤维型消毒剂 | |
EP2855761B1 (en) | Antitoxic fibers and fibrous media and methods for manufacturing same | |
EP2819711B1 (de) | Antiseptische wundauflage | |
KR20130057179A (ko) | 천연항생물질인 프로폴리스의 활동성분 또는 자몽종자추출물을 함유한 의료용 제품 및 그 제조방법 | |
CN114073921A (zh) | 一种复合微球及其制备方法和应用 | |
US20110052651A1 (en) | Antimicrobial compositions and products | |
EP4195967A1 (de) | Textiles flächengebilde mit virenhemmender ausrüstung | |
JP2021138774A (ja) | 人体用害虫忌避剤 | |
US11352715B2 (en) | Active apparel and fabric and coverings | |
EP1703014A1 (en) | Allergen suppressor, allergen-suppression processed fiber and method of producing the same | |
US20230320351A1 (en) | Antibacterial and antiviral fabric, formulation for soft coating and method of fabricating the same | |
AT521126A2 (de) | Sprühpflasterzusammensetzung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB02 | Change of applicant information | ||
CB02 | Change of applicant information |
Address after: Gyeonggi Do, South Korea Applicant after: HUONS CO.,LTD. Applicant after: Huines Medical Co.,Ltd. Address before: Gyeonggi Do, South Korea Applicant before: HUONS CO.,LTD. Applicant before: Fuminkang Medical Instrument Co.,Ltd. |
|
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Jin Beiyong Inventor after: Li Dongri Inventor after: Li Enqing Inventor after: Kang Minxi Inventor after: Zhao Zaimin Inventor after: Wu Junjiao Inventor after: Li Xiangwan Inventor before: Jin Beiyong Inventor before: Li Dongri Inventor before: Li Enqing Inventor before: Kang Minxi Inventor before: Zhao Zaimin Inventor before: Wu Junjiao |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40068800 Country of ref document: HK |
|
GR01 | Patent grant | ||
GR01 | Patent grant |