CN114099411A

CN114099411A - Self-repairing small needle nutrient solution formula

Info

Publication number: CN114099411A
Application number: CN202111430479.9A
Authority: CN
Inventors: 赵彬
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-11-29
Filing date: 2021-11-29
Publication date: 2022-03-01

Abstract

The invention discloses a formula of an autologous repair small needle nutrient solution, and relates to the technical field of medical cosmetology, wherein the preparation of an S1 repair solution, an S2 nutrient solution and an S3 adaptation solution are included. This little needle nutrient solution prescription repair liquid of autorestoration can inject into affected part along with the nutrient solution together, repair liquid can arouse the regeneration rate of affected part cell, this can promote the absorption effect of nutrient solution, arouse the regeneration rate of affected part cell simultaneously and enable the patient and carry out the autorestoration, this reduction affected part healing time that can be very big, adaptation liquid can strengthen human skin to nutrient solution, repair liquid's adaptability, avoid injecting into the too big inflammation of volume and say the infection, nutrient solution simultaneously, repair liquid and adaptation liquid's proportion can be adjusted according to the in service behavior, this makes the use of nutrient solution can nimble activation, make it can adapt to different patients and can reduce medical cosmetic operation risk.

Description

Self-repairing small needle nutrient solution formula

Technical Field

The invention relates to the technical field of medical cosmetology, in particular to a formula of a self-repairing small needle nutrient solution.

Background

The minimally invasive beauty treatment is a minimally invasive technology which is used for medical beauty treatment and has the characteristics of small wound, safety, rapidness, light pain and quick recovery, so the minimally invasive beauty treatment is favored by more and more beauty lovers, the injection of the small needle beauty treatment is one of the minimally invasive beauty treatment, the injection of the small needle beauty treatment is a beauty treatment method for beautifying the face contour and improving the skin texture to obtain the youthful and beautified face, and for patients, the injection beauty treatment has the advantages of small pain, safety, effectiveness, quick response, short downtime or no treatment.

The existing nutrient solution for injecting small needles for beauty treatment has single function, does not have the functions of allergy prevention and self-adaption, and causes allergic reaction easily caused after the patients are injected.

Disclosure of Invention

The invention aims to provide a self-repairing small needle nutrient solution formula to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: the self-repairing small needle nutrient solution formula comprises the following operation steps:

s1, preparation of a repairing liquid:

mixing 40 parts of normal saline, 5 parts of epidermal growth factor, 5 parts of water-soluble vitamin E, 10 parts of ceramide, 3 parts of allantoin, 7 parts of coenzyme Q10 and 30 parts of fat stem cell suspension.

S2, preparation of nutrient solution:

mixing 40 parts of normal saline, 25 parts of collagen peptide, 10 parts of sodium selenite, 20 parts of provitamin B5, 10 parts of hyaluronic acid and 5 parts of trace element permeation promoting factors.

S3, preparing an adaptation solution:

mixing 40 parts of normal saline, 10 parts of aloe juice, 10 parts of ursolic acid, 15 parts of bear antioxidant molecules, 10 parts of brown algae polysaccharide and ascorbic acid.

Preferably, in the step S1, the adipose stem cell suspension is prepared by mixing physiological saline and adipose stem cells.

Preferably, in the step S1, the repair solution is prepared by mixing a centrifuge and a centrifuge tube.

Preferably, in step S2, the trace element permeation promoting factor is prepared by blending trace elements (magnesium, chlorine, sodium, calcium, iron, zinc, manganese, copper, iodine, potassium) and physiological saline.

Preferably, in the S2 step, the nutrient solution is stored in a low-temperature storage chamber at 0-5 ℃.

Preferably, in the step S3, the antioxidant molecule is synthesized by using superoxide dismutase and protocatechuic acid.

Preferably, in the step S3, the ascorbic acid is vitamin C and the ascorbic acid is 15 parts.

The invention provides a self-repairing small needle nutrient solution formula, which has the following beneficial effects:

1. the repair liquid can be injected into the affected part along with the nutrient solution, the repair liquid can stimulate the regeneration speed of cells of the affected part, the absorption effect of the nutrient solution can be improved, the regeneration speed of the cells of the affected part can be stimulated to enable a patient to carry out self-repair, the healing time of the affected part can be greatly reduced, and the whole period of medical treatment and cosmetology can be greatly reduced.

2. The adaptation liquid can strengthen the adaptability of human skin to nutrient solution, repair liquid, avoids the too big inflammation speech infection of injection volume, and the proportion of nutrient solution, repair liquid and adaptation liquid can be adjusted according to the in service behavior simultaneously, and this makes the use of nutrient solution flexible activation for it can adapt to different patients, and can reduce medical cosmetic operation risk.

Detailed Description

The invention provides the technical scheme that: the self-repairing small needle nutrient solution formula comprises the following operation steps:

s1, preparation of a repairing liquid:

40 parts of normal saline: the physiological saline can assist the mixing of various solutions, and the physiological saline has the characteristics of sterility and safety,

5 parts of epidermal growth factor: the epidermal growth factor can promote the healing of skin wound and increase the skin elasticity;

5 parts of water-soluble vitamin E: the water-soluble vitamin E can delay skin cell aging, has the effects of resisting oxidation and removing free radicals, can maintain normal cell metabolism, and can improve the circulation of blood and capillary vessels so as to accelerate the speed of autologous repair of a patient;

10 parts of ceramide: the ceramide has the effects of resisting skin aging, whitening, moisturizing and resisting allergy, can participate in regulating various cell activities such as cell growth, proliferation, differentiation, apoptosis, injury and the like, can effectively accelerate the autologous repair speed of a patient, and has a better anticancer effect;

3 parts of allantoin: the allantoin has the effects of repairing skin injury, promoting cell growth, softening keratin layer, and promoting wound healing, and also has the effects of moistening skin, keeping moisture, and relieving inflammation, and can prevent inflammation and infection of wound;

7 parts of coenzyme Q10: coenzyme Q10 can inhibit lipid peroxidation, reduce the generation of free radicals, and protect the active center and the structure of superoxide dismutase from being damaged by the oxidation of free radicals, and coenzyme Q10 has the functions of resisting apoptosis, maintaining the integrity and stability of cell membranes, and enhancing cell metabolism, so that the regeneration speed of cells in affected parts can be increased;

30 parts of adipose-derived stem cell suspension: the adipose-derived stem cell suspension is a suspension prepared by mixing normal saline and adipose-derived stem cells, wherein the adipose-derived stem cells are prepared by separating and culturing adipose tissues of a human body, and mainly recover the repairing function of the tissue cells, so that the regeneration of affected cells can be promoted, and the body function can be improved.

Solution preparation:

injecting 30 parts of normal saline into a centrifugal test tube, sequentially injecting 5 parts of epidermal growth factor, 5 parts of water-soluble vitamin E, 10 parts of ceramide, 3 parts of allantoin and 7 parts of coenzyme into the centrifugal test tube, putting the centrifugal test tube into a centrifuge, starting the centrifuge, working for 5min, centrifugally mixing the raw materials, pumping out a mixed solution by using a needle tube after mixing, discarding precipitates in the centrifugal test tube, injecting the pumped out mixed solution into a sealed test tube, putting the test tube into a sterilization box for sterilization, wherein the temperature of the sterilization box is 55-60 ℃, the working time is 20min, and after sterilization is finished, putting the mixed solution into a storage chamber at 0-5 ℃ for refrigeration for later use.

And injecting 10 parts of physiological saline and 30 parts of adipose-derived stem cell suspension into a centrifugal test tube, starting a centrifugal machine, working for 1min, diluting the adipose-derived stem cell suspension by the physiological saline so as to facilitate the adipose-derived stem cell suspension to absorb other liquids, dividing the mixed solution into three equal parts, sequentially injecting the three equal parts into the diluted adipose-derived stem cell suspension, centrifugally mixing, wherein the first centrifugal mixing time and the second centrifugal mixing time are 3min, and the third mixing time is 5min, preparing a repair solution after the mixed solution and the adipose-derived stem cell suspension are mixed, extracting the prepared repair solution by using a straw, discarding precipitates in the centrifugal test tube, injecting the prepared repair solution into a vacuum bag, and placing in a storage chamber at 0-5 ℃ for refrigeration.

S2, preparation of nutrient solution:

40 parts of normal saline: the physiological saline can assist the mixing of various solutions, and the physiological saline has the characteristics of sterility and safety

35 parts of collagen peptide: the collagen peptide glue is high-molecular functional protein, the collagen peptide has high nutrition, and meanwhile, the collagen peptide can form a fine elastic net in the skin to firmly lock water to support the skin, so that the absorption effect of the nutrient solution can be improved;

20 parts of provitamin B5: the provitamin B5 has the effects of activating epithelial cells and promoting the generation of the epithelial cells, can promote the absorption of the cells to nutrient substances by activating the epithelial cells, has the functions of diminishing inflammation and helping wound healing, can promote the healing speed of wounds, has the functions of resisting allergic dermatitis, detoxifying and preserving moisture, and can greatly reduce the allergic state of a patient;

10 parts of hyaluronic acid: the hyaluronic acid has repairing, nourishing and moisturizing effects on damaged skin, has lubricating and film-forming properties, and can thicken the nutrient solution to improve the mixing stability of the nutrient solution.

5 parts of trace element permeation promoting factor, wherein the trace element permeation promoting factor is prepared by mixing trace elements (magnesium, chlorine, sodium, calcium, iron, zinc, manganese, copper, iodine and potassium) and normal saline, and can promote the permeation of various nutrient components to subcutaneous tissues, so that the absorption effect of a human body on nutrient solution can be improved.

Solution preparation: injecting 30 parts of normal saline into a centrifugal test tube, sequentially injecting 10 parts of hyaluronic acid and 20 parts of provitamin B5 into the normal saline, operating a centrifugal machine for 10min, mixing the three, extracting a mixed solution by using a needle tube after mixing is finished, and discarding internal precipitates;

injecting 35 parts of collagen peptide and 10 parts of normal saline into a centrifugal test tube, operating a centrifugal machine for 3min to mix and dilute the normal saline and the collagen peptide, injecting all mixed liquid into the diluted collagen peptide after mixing and diluting, starting the centrifugal machine for 3min to preliminarily mix liquid, injecting 5 parts of trace element permeation promoting factors into the mixed liquid, starting the centrifugal machine to operate for 10min to completely mix the liquid, and thus, completing the preparation of the nutrient solution, extracting the nutrient solution by using a needle tube, discarding precipitates in the nutrient solution, injecting the prepared nutrient solution into a vacuum bag, and then placing the vacuum bag into a storage chamber with the temperature of 0-5 ℃ for refrigeration for later use.

S3, preparing an adaptation solution:

40 parts of normal saline: the physiological saline can assist the mixing of various solutions, and the physiological saline has the characteristics of sterility and safety;

10 parts of aloe juice: the aloe liquid has better mildness, almost completely coincides with substances required by human cells, can improve the adaptability and the rejection of the adaptation liquid and a human body, and simultaneously, the aloe is a herbaceous plant and can reduce the loss of chemical substances to the skin of the human body;

10 parts of ursolic acid: ursolic acid is a triterpenoid existing in natural plants, has various biological effects of tranquilizing, resisting inflammation, resisting bacteria, resisting diabetes, resisting ulcer, reducing blood sugar and the like, can improve the suitability of adaptation liquid and a human body, has an obvious antioxidant function, is a herbal plant extract, and can reduce damage to the human body;

15 parts of antioxidant molecules: the antioxidant molecules are synthesized by superoxide dismutase and protocatechuic acid, can prevent skin from contacting with external harmful substances to generate rejection reaction, and can help to capture and neutralize free radicals, so that the damage of the free radicals to a human body is eliminated, and the adaptability of the adaptive liquid to the human body is improved;

10 parts of brown algae polysaccharide: the brown algae polysaccharide is prepared by mixing extracts of seaweeds such as kelp, Ascophyllum nodosum and Fucus vesiculosus, has the function of removing active oxygen, can also obviously reduce the content of lipid peroxide, improves the activity of peroxidase and superoxide dismutase, has the functions of removing excessive free radicals and resisting lipid peroxidation, and can improve the adaptability of the adaptation liquid to a human body;

15 parts of ascorbic acid: the ascorbic acid is vitamin C, which can improve the activity of the skin, thus improving the adaptation speed of the skin and the adaptation liquid, although the vitamin C has strong reducibility and is easy to contact with air to be oxidized into dehydrovitamin C, the oxidation of the vitamin C can be greatly reduced by contacting with antioxidant molecules.

Injecting 10 parts of normal saline and 10 parts of aloe solution into a centrifugal test tube, mixing for 5min, then injecting 10 parts of normal saline and 10 parts of ursolic acid into the centrifugal test tube, mixing for 5min, then injecting 10 parts of normal saline and 10 parts of brown algae polysaccharide into the centrifugal test tube, mixing for 5min to obtain three parts of herbal mixed solution, then sequentially injecting 10 parts of normal saline, 15 parts of antioxidant molecules and 15 parts of ascorbic acid into the centrifugal test tube, starting a centrifugal machine, mixing for 10min, after mixing, injecting three parts of herbal mixed solution into mixed solution of normal saline, antioxidant molecule and ascorbic acid for three times, wherein the single mixing time is 7min, after mixing, preparing adaptation liquid, extracting the adaptation liquid with needle tube, discarding the precipitate, injecting the prepared adaptation liquid into vacuum bag, and refrigerating in 0-5 deg.C storage chamber.

Use after preparation was complete:

(1) the test flow comprises the following steps: injecting the mixed solution of the micronutrient solution and the repairing solution into the affected part of the patient, observing for 30min, and observing whether the affected part of the patient has inflammatory reaction.

(2) Normal patient use procedure: the affected part of the patient has no inflammatory reaction, 300ml of nutrient solution, 150ml of repair solution and 50ml of adaptation solution are taken and mixed, the mixed solution is extracted by using a small needle and injected into the affected part of the patient, and the adaptation solution can enhance the adaptability of the skin of the human body to the nutrient solution and the repair solution and avoid inflammation and speech infection caused by excessive injection amount.

(3) The use process of the inflammation patients is as follows: if the affected part of the patient has inflammatory reaction in the test process, retesting is carried out by using a mixed solution of nutrient solution, repair solution and adaptation solution (the proportion of the nutrient solution and the repair solution is 6 parts in total, and the adaptation solution is 4 parts), the mixed solution with a trace amount is injected into the affected part and then is tested, after observation is carried out for 30min, after the affected part of the patient has no inflammatory reaction, 200ml of nutrient solution, 100ml of repair solution and 200ml of adaptation solution are taken and mixed, and are divided into a plurality of parts, the mixed solution is extracted by using a small needle, the mixed solution is injected into the affected part of the patient for a plurality of times, and the proportion of the nutrient solution, the repair solution and the adaptation solution can be adjusted according to the use condition, so that the use of the nutrient solution can be activated flexibly, the patient can adapt to different patients, and the surgical risk of medical cosmetology can be reduced.

Claims

1. The self-repairing small needle nutrient solution formula is characterized by comprising the following operation steps:

s1, preparation of a repairing liquid:

S2, preparation of nutrient solution:

S3, preparing an adaptation solution:

2. The self-repairing small needle nutrient solution formulation as claimed in claim 1, wherein in the step S1, the adipose stem cell suspension is prepared by mixing normal saline and adipose stem cells.

3. The self-repairing small needle nutrient solution formula as claimed in claim 1, wherein in the step S1, a centrifuge and a centrifuge tube are used for preparing the repairing solution.

4. The self-repairing small needle nutrient solution formulation as claimed in claim 1, wherein in the step S2, the trace element penetration promoting factor is prepared from trace elements (magnesium, chlorine, sodium, calcium, iron, zinc, manganese, copper, iodine, potassium) and normal saline.

5. The self-repairing small needle nutrient solution formulation as claimed in claim 1, wherein in the step of S2, the nutrient solution is stored in a low-temperature storage chamber at 0-5 ℃.

6. The self-repairing small needle nutrient solution formula as claimed in claim 1, wherein in the step of S3, the antioxidant molecules are synthesized by using superoxide dismutase and protocatechuic acid.

7. The self-repairing small needle nutrient solution formula as claimed in claim 1, wherein in the step of S3, the ascorbic acid is vitamin C, and the ascorbic acid is 15 parts.