CN114073288A - Antioxidant composition containing quercitrin - Google Patents
Antioxidant composition containing quercitrin Download PDFInfo
- Publication number
- CN114073288A CN114073288A CN202010815810.8A CN202010815810A CN114073288A CN 114073288 A CN114073288 A CN 114073288A CN 202010815810 A CN202010815810 A CN 202010815810A CN 114073288 A CN114073288 A CN 114073288A
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- antioxidant
- composition
- antioxidant composition
- feed
- quercetagetin
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- 239000003963 antioxidant agent Substances 0.000 title claims abstract description 58
- 239000000203 mixture Substances 0.000 title claims abstract description 50
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 48
- LUJAXSNNYBCFEE-UHFFFAOYSA-N Quercetin 3,7-dimethyl ether Natural products C=1C(OC)=CC(O)=C(C(C=2OC)=O)C=1OC=2C1=CC=C(O)C(O)=C1 LUJAXSNNYBCFEE-UHFFFAOYSA-N 0.000 title claims abstract description 5
- PUTDIROJWHRSJW-UHFFFAOYSA-N Quercitrin Natural products CC1OC(Oc2cc(cc(O)c2O)C3=CC(=O)c4c(O)cc(O)cc4O3)C(O)C(O)C1O PUTDIROJWHRSJW-UHFFFAOYSA-N 0.000 title claims abstract description 5
- OXGUCUVFOIWWQJ-XIMSSLRFSA-N acanthophorin B Natural products O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OXGUCUVFOIWWQJ-XIMSSLRFSA-N 0.000 title claims abstract description 5
- OEKUVLQNKPXSOY-UHFFFAOYSA-N quercetin 3-O-beta-D-glucopyranosyl(1->3)-alpha-L-rhamnopyranosyl(1->6)-beta-d-galactopyranoside Natural products OC1C(O)C(C(O)C)OC1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OEKUVLQNKPXSOY-UHFFFAOYSA-N 0.000 title claims abstract description 5
- QPHXPNUXTNHJOF-UHFFFAOYSA-N quercetin-7-O-beta-L-rhamnopyranoside Natural products OC1C(O)C(O)C(C)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 QPHXPNUXTNHJOF-UHFFFAOYSA-N 0.000 title claims abstract description 5
- OXGUCUVFOIWWQJ-HQBVPOQASA-N quercitrin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OXGUCUVFOIWWQJ-HQBVPOQASA-N 0.000 title claims abstract description 5
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N quercetagetin Chemical compound C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims abstract description 65
- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims abstract description 21
- 238000007254 oxidation reaction Methods 0.000 claims abstract description 14
- 230000003647 oxidation Effects 0.000 claims abstract description 13
- 238000000034 method Methods 0.000 claims abstract description 12
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 claims abstract description 6
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 claims abstract description 3
- 235000006708 antioxidants Nutrition 0.000 claims description 55
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims description 10
- 239000003674 animal food additive Substances 0.000 claims description 8
- 239000003925 fat Substances 0.000 claims description 8
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- 229940088594 vitamin Drugs 0.000 claims description 6
- 229930003231 vitamin Natural products 0.000 claims description 6
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- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims description 5
- 235000021466 carotenoid Nutrition 0.000 claims description 5
- 150000001747 carotenoids Chemical class 0.000 claims description 5
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims description 5
- 229960001285 quercetin Drugs 0.000 claims description 5
- 235000005875 quercetin Nutrition 0.000 claims description 5
- 235000005881 Calendula officinalis Nutrition 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 3
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000002738 chelating agent Substances 0.000 claims description 2
- 239000003995 emulsifying agent Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 229910021645 metal ion Inorganic materials 0.000 claims description 2
- 239000003094 microcapsule Substances 0.000 claims description 2
- 241000736851 Tagetes Species 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 1
- 235000019197 fats Nutrition 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 230000000979 retarding effect Effects 0.000 claims 1
- 230000009044 synergistic interaction Effects 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 16
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 13
- 238000002156 mixing Methods 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 9
- 239000002994 raw material Substances 0.000 description 8
- 239000000377 silicon dioxide Substances 0.000 description 8
- 235000012239 silicon dioxide Nutrition 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 150000002978 peroxides Chemical class 0.000 description 4
- 239000004519 grease Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 235000013332 fish product Nutrition 0.000 description 2
- 230000001590 oxidative effect Effects 0.000 description 2
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- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 235000019542 Cured Meats Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 239000004258 Ethoxyquin Substances 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 235000019764 Soybean Meal Nutrition 0.000 description 1
- 240000000785 Tagetes erecta Species 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- -1 and the like Chemical compound 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000015496 breakfast cereal Nutrition 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
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- 230000029087 digestion Effects 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 235000019285 ethoxyquin Nutrition 0.000 description 1
- DECIPOUIJURFOJ-UHFFFAOYSA-N ethoxyquin Chemical compound N1C(C)(C)C=C(C)C2=CC(OCC)=CC=C21 DECIPOUIJURFOJ-UHFFFAOYSA-N 0.000 description 1
- 229940093500 ethoxyquin Drugs 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019261 food antioxidant Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 235000008446 instant noodles Nutrition 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 229910000357 manganese(II) sulfate Inorganic materials 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3544—Organic compounds containing hetero rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3472—Compounds of undetermined constitution obtained from animals or plants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/349—Organic compounds containing oxygen with singly-bound oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fodder In General (AREA)
- Medicinal Preparation (AREA)
Abstract
The application relates to an antioxidant composition, which contains quercitrin and one or two of EQ (ethoxyquinoline) and BHT (dibutyl hydroxy toluene). The quercetagetin is compounded with the common antioxidants of EQ, BHT and the like in the feed at present, has obvious synergistic interaction, can effectively delay the oxidation process of the feed, and ensures the stability of the feed.
Description
Technical Field
The invention belongs to the field of feed additives, and particularly relates to an antioxidant composition containing quercetagetin and application thereof.
Background
During the laying process of the feed, the effective components such as oil, vitamins, carotenoids and the like in the feed are subjected to oxidation reaction, so that the content of the effective components is reduced, wherein the oxidation of the oil is the most important. Oxidation of fats can lead to fat deterioration and off-flavors. Oxidative rancidity of fats can lead to a number of negative effects: the nutritional value of the oil is reduced; the oil is oxidized to generate bad smell, so that the palatability of the feed is poor, and the ingestion of animals is influenced; the secondary product of the oil oxidation reacts with protein to reduce the digestion and absorption of the protein; the oxidation products of the oil and fat have destructive effect on the vitamins and the like.
In order to delay the oxidation of feed, synthetic antioxidants such as EQ, BHT, and the like, BHT, namely dibutyl hydroxy toluene, also known as 2, 6-di-tert-butyl-p-cresol, are commonly added into feed at present. The dibutyl hydroxy toluene is white crystal or crystalline powder, basically odorless and tasteless, has a melting point of 69.5-71.5 ℃, a boiling point of 265 ℃, and is quite stable to heat. The dibutyl hydroxy toluene can be used for edible oil and fat, fried food, dried fish product, biscuit, instant noodle, instant rice, canned nut, cured meat product, breakfast cereal food, and its maximum usage amount is 0.2 g/kg. EQ, ethoxyquinoline. The ethoxyquin is one of feed antioxidants with excellent performance, is the most economic antioxidant, is suitable for premix, fish meal and products added with fat, can prevent vitamin A, D, E and the like in the premix, prevent fat oxygen from deteriorating natural pigment from oxidative discoloration, and has certain mildew-proof and fresh-keeping effects; in addition, the product can be used as food antioxidant, fruit preservative and rubber antioxidant.
Quercetin, chemical name is 3,3,4,5,6, 7-hexahydroxyflavone, has important pharmacological actions of resisting oxidation, inflammation, allergy and tumor, etc. It is mainly derived from plant extracts. At present, the research on the quercetagetin mainly focuses on the pharmacological activity of the quercetagetin, and the quercetagetin is not applied to the field of feed antioxidants.
The application finds that the quercetagetin and the synthetic feed antioxidants such as EQ, BHT and the like which are commonly used at present are compounded for use, so that the synergistic effect is obvious, the oxidation process of the feed can be effectively delayed, and the stability of the feed is ensured.
Disclosure of Invention
In order to improve the antioxidation effect of the feed, the invention provides an antioxidation composition containing quercetagetin, which produces obvious synergistic effect by compounding the quercetagetin with the commonly used synthetic feed antioxidants such as EQ, BHT and the like at present.
The technical scheme adopted by the invention for solving the technical problems is as follows: an antioxidant composition contains quercitrin, and one or two of EQ and BHT.
The application further provides an antioxidant composition, wherein the content of quercetagetin in the composition is 1-50% of the total antioxidant; preferably 5% -40%; further preferably 10% to 30%.
The application further provides an antioxidant composition, wherein the content of quercetagetin in the composition in total antioxidants can be preferably 10-28%; or 10-26%; or 10-24%; or 10-22%; or 10-20%; or 10-18%; or 10-16%; or 10-14%; or 10-12%; also preferably 12-30%; 12 to 28 percent; or 12-26%; or 12-24%; or 12-22%; or 12-20%; or 12 to 18 percent; or 12-16%; or 12-14%; also preferably 14-30%; 14 to 28 percent; or 14-26%; or 14-24%; or 14-22%; or 14-20%; or 14-18%; or 14-16%; also preferably 16-30%; 16 to 28 percent; or 16-26%; or 16-24%; or 16-22%; or 16-20%; or 16-18%; also preferably 18-30%; 18 to 28 percent; or 18 to 26 percent; or 18 to 24 percent; or 18-22%; or 18-20%; also preferably 20-30%; 20 to 28 percent; or 20-26%; or 20-24%; or 20-22%; also preferably 22-30%; 22 to 28 percent; or 22-26%; or 22-24%; also preferably 24-30%; 24 to 28 percent; or 24-26%; also preferably 26-30%; 26 to 28 percent; it is also preferably 28 to 30%.
Further, in the above antioxidant composition, the content of quercetagetin in the total antioxidant may be 50%, 49%, 48%, 47%, 46%, 45%, 44%, 43%, 42%, 41%, 40%, 39%, 38%, 37%, 36%, 35%, 34%, 33%, 32%, 31%, 30%, 29%, 28%, 27%, 26%, 25%, 24%, 23%, 22%, 21%, 20%, 19%, 18%, 17%, 16%, 15%, 14%, 13%, 12%, 11%, 10%, 9%, 8%, 7%, 6%, 5%, 4%, 3%, 2%, 1%.
The quercetagetin is obtained by plant extraction or chemical synthesis.
The total antioxidant refers to the sum of all active substances with antioxidant effect in the composition.
The content of quercetagetin in total antioxidant is the mass percentage of quercetagetin and total antioxidant.
Furthermore, the dosage ratio of EQ to BHT in the antioxidant combination is arbitrary.
Furthermore, the antioxidant composition also comprises one or more components such as a suitable carrier, a metal ion chelating agent, an emulsifier, and the like.
The antioxidant composition can be used as a feed additive, can effectively delay the oxidation process of each component in the feed, and ensures the stability of the feed quality.
The antioxidant composition can effectively delay the oxidation process of components such as grease, vitamins, carotenoids and the like, and ensure the stability of the components.
The antioxidant composition can be used as a feed additive, can effectively delay the oxidation process of components such as grease, vitamins, carotenoids and the like, and ensures the stability of the feed quality.
The application also provides a feed additive, namely the composition is prepared into any acceptable and suitable feed additive preparation according to a conventional preparation method, and the acceptable and suitable feed additive preparation can be preferably processed into powder, liquid or microcapsule.
The invention has the beneficial effects that:
the inventor of the application finds that when the quercetagetin and the synthetic antioxidants such as EQ, BHT and the like are compounded and used according to a certain proportion, the quercetagetin-containing composition has an obvious synergistic effect, under the same additive amount, the protection effect of the quercetagetin-containing composition on grease, vitamins, carotenoids and the like in the feed is obviously better than that of the quercetagetin-containing composition or the antioxidants such as EQ, BHT and the like which are used independently, the oxidation process of the feed can be further delayed, and the quality of the feed in the storage process can be guaranteed.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1
The antioxidant composition of example 1 was prepared by mixing the following raw materials in proportions: 12.5g of 80 percent content of quercetagetin, 40.8g of 98 percent content of EQ and 46.7g of carrier silicon dioxide, and the mixed composition contains 10 percent of quercetagetin, 40 percent of EQ and 20 percent of quercetagetin in the total antioxidant.
Example 2
The antioxidant composition of example 2 was prepared by mixing the following raw materials in proportions: 37.5g of 80% content of quercetagetin, 60.6g of 99% content of BHT60, and 1.9g of carrier silicon dioxide, wherein the mixed composition contains 30% of quercetagetin, 60% of BHT, and the proportion of quercetagetin in total antioxidant is 33%.
Example 3
The antioxidant composition of example 3 was prepared by mixing the following raw materials in proportions: 0.6g of 80% quercetagetin, 19.7g of BHT19.7g of 99% content, 30.6g of EQ of 98% content, carrier silicon dioxide, 40.1g, and the mixed composition contains 0.5% quercetagetin, 19.5% BHT, 30% EQ and 1% quercetagetin in of total antioxidant.
Example 4
The antioxidant composition of example 4 was prepared by mixing the following raw materials in proportions: 31.3g of 80% pure quercetagetin, 25.5g of 98% EQ, 43.2g of carrier silicon dioxide, 25% of quercetagetin, 25% EQ in the mixed composition, and 50% of quercetagetin in the total antioxidant.
Comparative example 1
The antioxidant composition of comparative example 1 was prepared by mixing the following raw materials in proportions: 98% of EQ40.8g and 59.2g of carrier silica, and the mixed composition contains EQ 40%.
Comparative example 2
The antioxidant composition of comparative example 2 was prepared by mixing the following raw materials in proportions: 99% BHT60.6g and carrier silica 39.4g, and the mixed composition contains BHT 60%.
Comparative example 3
The antioxidant composition of comparative example 3 was prepared by mixing the following raw materials in proportions: 99% BHT3.0g, 98% EQ6.1g, and 90.9g carrier silicon dioxide, and the mixed composition contains BHT 3% and EQ 6%.
Comparative example 4
The antioxidant composition of comparative example 4 was prepared by mixing the following raw materials in proportions: 80% of QG50g, 50g of carrier silicon dioxide, and 40% of quercetin marigold after mixing.
Evaluation of antioxidant effect:
(1) pulverizing semen Maydis and soybean meal;
(2) self-made premix formula (CuSO)4 51％+FeSO4 32％+MnSO417%) for uniform mixing, equal amounts of SiO were added2Fully and uniformly mixing by using a grinder;
(3) preparing feed (corn 74.5% + bean pulp 20% + premix 0.5% + soybean oil 5%), adding the antioxidant of examples 1-4 and comparative examples 1-4 respectively to prepare 7 groups of samples with antioxidant content of 150ppm, wherein the antioxidant content is calculated by the total content of antioxidant active ingredients, additionally setting blank control groups, repeating three groups, mixing the samples uniformly, and placing the samples in a beaker in a sealing way;
(4) evaluation indexes are as follows: peroxide number
(5) Storage conditions are as follows: the mixture was allowed to stand at 55 ℃ and 60% humidity for 5 days.
The antioxidant value of each sample was measured after standing for 5 days under the above-mentioned storage conditions. The results are shown in Table 1.
The peroxide value is determined by the following method: the detection is carried out according to the method of GB 5009.227-2016 determination of peroxide value in food safety national standard food.
TABLE 1 peroxide number determination of feeds with different antioxidant compositions
Claims (8)
1. An antioxidant composition contains quercitrin, and one or two of EQ (ethoxyquinoline) and BHT (dibutylhydroxytoluene).
2. The antioxidant composition of claim 1, wherein the quercetin marigold is present in the composition in an amount of 1% to 50% of the total antioxidants.
3. The antioxidant composition of claim 2, wherein the quercetin marigold is present in the composition in an amount of 5% to 40% of the total antioxidants.
4. The antioxidant composition of claim 3, wherein the quercetin marigold is present in the composition in an amount of 10% to 30% of the total antioxidants.
5. The antioxidant composition of any of claims 1 to 4, further comprising one or more ingredients selected from the group consisting of suitable carriers, metal ion chelating agents, emulsifiers, and the like.
6. A feed additive formulation comprising the antioxidant composition of any of claims 1-5 and prepared according to any conventional formulation method, preferably processed into a powder, liquid or microcapsule.
7. Use of an antioxidant composition as claimed in any of claims 1 to 6 as a feed additive to ensure the stability of the feed quality.
8. Use of an antioxidant composition as claimed in any of claims 1-7 for retarding the oxidation process of active ingredients like fats and oils, vitamins, carotenoids etc.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103181453A (en) * | 2011-12-27 | 2013-07-03 | 北京资源亚太动物药品有限公司 | Feed antioxidant |
| CN103549222A (en) * | 2013-11-22 | 2014-02-05 | 安徽科技学院 | Compound feed additive for preventing piglet diarrhea and preparation method thereof |
| CN105831424A (en) * | 2016-04-12 | 2016-08-10 | 重庆威士化工有限公司 | A feed antioxidant resisting self attenuation, a preparing method thereof and a feed antioxidation method |
| CN107156523A (en) * | 2017-06-27 | 2017-09-15 | 皖西学院 | A kind of free range chicken feed and preparation method thereof |
| WO2021223682A1 (en) * | 2020-05-06 | 2021-11-11 | 晨光生物科技集团股份有限公司 | Quercetagetin-containing feed and use thereof |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103181453A (en) * | 2011-12-27 | 2013-07-03 | 北京资源亚太动物药品有限公司 | Feed antioxidant |
| CN103549222A (en) * | 2013-11-22 | 2014-02-05 | 安徽科技学院 | Compound feed additive for preventing piglet diarrhea and preparation method thereof |
| CN105831424A (en) * | 2016-04-12 | 2016-08-10 | 重庆威士化工有限公司 | A feed antioxidant resisting self attenuation, a preparing method thereof and a feed antioxidation method |
| CN107156523A (en) * | 2017-06-27 | 2017-09-15 | 皖西学院 | A kind of free range chicken feed and preparation method thereof |
| WO2021223682A1 (en) * | 2020-05-06 | 2021-11-11 | 晨光生物科技集团股份有限公司 | Quercetagetin-containing feed and use thereof |
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