CN109258935A - Feed growth promotion oxidation-resistant compound additive and its preparation method and application - Google Patents
Feed growth promotion oxidation-resistant compound additive and its preparation method and application Download PDFInfo
- Publication number
- CN109258935A CN109258935A CN201811176313.7A CN201811176313A CN109258935A CN 109258935 A CN109258935 A CN 109258935A CN 201811176313 A CN201811176313 A CN 201811176313A CN 109258935 A CN109258935 A CN 109258935A
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- feed
- parts
- growth promotion
- product
- food
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Classifications
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- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
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- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
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- A—HUMAN NECESSITIES
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- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/10—Foods or foodstuffs containing additives; Preparation or treatment thereof containing emulsifiers
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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Abstract
The present invention relates to field of feed additive technology, especially a kind of feed growth promotion oxidation-resistant compound additive and its preparation method and application is prepared by following substance by appended parts by weight: 100 parts of glycocyamine, 10-90 parts of antioxidant, 5-20 parts of emulsifier, 5-30 parts of synergist, 15-70 parts of anticaking agent.Preparation method is: (1) smashing thicker solid material at fineness is more than that 60 mesh powder shape materials are spare;(2) liquid or material paste and anticaking agent are mixed into runny powdery intermediate products;(3) sieving is packaged into product after being sufficiently mixed various materials uniformly.The present invention passes through glycocyamine and the reasonable compatibility of various antioxidants, synergistic function is played on growth promotion and antioxidation, the use of emulsifier and synergist can increase diffusion and infiltration, synergistic function is further promoted, then the remuneration for improving feed promotes production to animal, is anti-oxidant, removing free radical and health care etc. play a significant role.
Description
Technical field
The present invention relates to feed additive field, specific field is a kind of feed growth promotion antioxidant.
Background technique
More than ten clenbuterol hydrochloride such as clenobuterol hydrochloride be China forbid using feed addition types of drugs, can be bright after use
The aobvious remuneration for improving feed and increase lean meat percentage.The product original is adrenin CNS stimulant, is treatment human asthma
Drug about once misuses in feed twenty years ago, causes biggish harm.Livestock technology worker is by exerting in the recent decade
Power, finally by glycocyamine with legal identity instead of drugs such as illegal Clenbuterols, be made that great tribute for animal husbandry
It offers, so that the remuneration of low-protein diet feed can also greatly improve, reduces nitrogen discharged in animal wastes.
Glycocyamine is growth accelerator, and synergistic function has been used in combination with glycine betaine or choline chloride, has been typically formulated
It is used at concentrated feed.But glycocyamine early stage is used in combination with various antioxidants, can promote respective growth promotion and antioxygen
Change function to have not been reported.
Summary of the invention
The purpose of the present invention is to provide a kind of feed growth promotion oxidation-resistant compound additive and preparation method thereof and answer
With to solve, the addition concentration height of each additive such as glycocyamine in the prior art, addition is at high cost, palatability is bad, uses
Inconvenient, the problems such as price of deed is low.
To achieve the above object, the invention provides the following technical scheme:
A kind of feed growth promotion oxidation-resistant compound additive is prepared by following substance by appended parts by weight: guanidine radicals
100 parts of acetic acid, 10-90 parts of antioxidant;5-20 parts of emulsifier;5-30 parts of synergist;15-70 parts of anticaking agent.
Feed of the present invention growth promotion oxidation-resistant compound additive, wherein the glycocyamine is feed grade guanidine
Guanidine-acetic acid, major function are growth promotions.
Feed of the present invention growth promotion oxidation-resistant compound additive, wherein the antioxidant is following several
One of group substance is a variety of:
A, Rosmarinus officinalis extract, including carnosic acid, carnosol, Rosmarinic acid, rosmanol and ursolic acid;
B, bamboo-leaves flavones, refer to bamboo extractive, and main component contains the complex mixtures such as flavonoids, lactone, phenolic acid class
General name;
C, turmeric refers to the rhizome of ginger tannin plant turmeric, includes the curcumin of 2%-6%;
D, grape pip, refers to the seed dried object of table grapes, wherein the polyphenoils component procyanidine contained, abbreviation OPC,
There are also the anti-oxidant families of other a small amount of natural organic acids compositions;
E, tea polyphenols, refer to green-tea extract polyphenol mixture general name, and polyphenol content is 30% or more;
F, tert-butyl hydroquinone TBHQ is chemically synthesized food or feed grade product;
G, butylhydroxy anisole BHA is chemically synthesized food or feed grade product;
H, di-tert-butyl hydroxy toluene BHT is chemically synthesized food or feed grade product;
I, propylgallate PG is chemically synthesized food or feed grade product;
J, ethoxyquinoline EQ is chemically synthesized food or feed grade product;
Feed of the present invention growth promotion oxidation-resistant compound additive, wherein the emulsifier is following kinds
One of or it is a variety of:
A. TWEEN Series: being chemically synthesized food or feed including polysorbas20, polysorbate40, polysorbate60, Tween 80
Grade product;
B. fatty glyceride: being chemically synthesized food including glycerin monostearate or single bi-tristearin
Product or feed grade product.
Feed of the present invention growth promotion oxidation-resistant compound additive, wherein the synergist be it is following a kind of or
Two kinds:
A. citric acid, for Citric Acid Mono or anhydrous citric acid, food or feed grade product;
B. propylene glycol, for 1,3-PD or 1,2-PD, food or feed grade product.
Feed of the present invention growth promotion oxidation-resistant compound additive, wherein the anticaking agent is feed grade two
Silica.
The preparation method of any feed growth promotion oxidation-resistant compound additive of the present invention, comprising the following steps:
A. to reach 60 mesh used above for ambient ground or fineness under nitrogen protection as required for the big raw material of particle;
B. liquid charging stock be prefabricated into anticaking agent silica 2.5:1 weight ratio powdered semi-finished product place respectively to
With;
C. paste raw materials are slightly heated up to 45 DEG C -55 DEG C, are prefabricated into semi-finished product with b method and place for use;
D. raw material of the weight ratio less than 1% uses after being diluted to 10%-50% concentration with silica premix, so as not to it is mixed
It is uneven to close stirring;
E. sieving, is packaged into product after various materials being sufficiently mixed uniformly;
Wherein, in production, inside is in the inertia protection of industrial nitrogen all devices, and reduction is contacted with air.
The application of any feed growth promotion oxidation-resistant compound additive of the present invention, addition 300- per ton in feed
1000 grams.
The present invention improves glycocyamine and various antioxidants under the multiple action of emulsifier and synergist, mentions significantly
High synergistic effect, reduces the additive amount when exclusive use of glycocyamine and antioxidant in feed.Guanidine radicals
Acetic acid is added in right amount to promote production and antioxidation, there is the side effect of enzymatic oxidation when additive amount is too big instead, a variety of anti-oxidant
Agent equally has this disadvantage, and additive amount is excessive, and the product after oxidation equally has the side effect of enzymatic oxidation.Invention also provides
The scientific and reasonable preparation method of feed growth promotion oxidation-resistant compound additive.
Compared with prior art, the beneficial effects of the present invention are:
(1) glycocyamine original is the derivative of amino acids, non-clenbuterol hydrochloride.Body can be made to generate a large amount of phosphoric acid after addition
Gene transfer substance (phosphocreatine) promotes energy source to provide power for the organizationally efficient work such as muscle, brain, sexual gland
Source is constantly distributed into musculature, and growth promoting function is played.And have been reported that glycine betaine and choline play synergy work
With.Glycocyamine additive amount has anti-oxidant and enzymatic oxidation dual positive negative action that can show when larger.Guanidine in the present invention
Guanidine-acetic acid somatotrophic additive amount in feed only needs half of normal usage or so that can achieve the desired results, and prevents to promote oxygen
The side effect of change.
(2) present invention is safely and effectively kind using 10 groups of antioxidants, when use in addition to having synergy mutually,
Also there is apparent synergistic effect to glycocyamine.Meanwhile the antioxidant effect of glycocyamine is easy to get to performance, and glycocyamine
Enzymatic oxidation side effect is overcome.
(3) emulsifier and synergist that the present invention uses, two analog assistant also functions to positive effect in the production process, it
It can make early stage between material that can diffuse into one another, permeate, merge.It is demonstrated experimentally that being added again in Feed Manufacturing each in the present invention
Class component, effect can not show a candle to the effect of product of the present invention.
(4) additive prepared by the present invention obviously reinforces the antioxidant effect of feed, and using effect proves, it is certain easily
The hay varieties of oxidation is handled using the method for a large amount of addition antioxidants, is given using can reasonably add after product of the present invention
To solve, never violation excess is added, that is, can solve the problem of feed oxide.
(5) present invention, which can efficiently solve animal vivo oxidation, to improve feed color with the function of eliminating free radical
On the basis of fragrance and the promotion price of deed, enhances animal immunizing power, improve the quality of meat, egg and milk, reduce various
The use of drug.
Product of the present invention can be obviously improved using the function of each component in early application than the later period respectively.This product adds
Add that concentration is low, function is strong, palatability is good, highly-safe, add at low cost, easy to use, the price of deed is high.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is general
Logical technical staff every other embodiment obtained without making creative work, belongs to protection of the present invention
Range.
Feed growth promotion oxidation-resistant compound additive is prepared by following substance by appended parts by weight: glycocyamine
100 parts, 10-90 parts of antioxidant;5-20 parts of emulsifier;5-30 parts of synergist;15-70 parts of anticaking agent.
Wherein, the glycocyamine is feed grade glycocyamine.
Wherein, the antioxidant is one of following several groups of substances or a variety of: a, Rosmarinus officinalis extract, including mouse
Tail oxalic acid, carnosol, Rosmarinic acid, rosmanol and ursolic acid;B, bamboo-leaves flavones refer to bamboo extractive;C, turmeric refers to
The rhizome of ginger tannin plant turmeric, includes the curcumin of 2%-6%;D, grape pip refers to the seed dried object of table grapes, wherein containing
Some polyphenoils component procyanidine;E, tea polyphenols refer to green-tea extract polyphenol mixture general name, polyphenol content 30%
More than;F, tert-butyl hydroquinone TBHQ is chemically synthesized food or feed grade product;G, butylhydroxy anisole
BHA is chemically synthesized food or feed grade product;H, di-tert-butyl hydroxy toluene BHT is chemically synthesized food or feeding
Expect grade product;I, propylgallate PG is chemically synthesized food or feed grade product;J, ethoxyquinoline EQ, for chemistry
The food or feed grade product of synthesis;
Wherein, the emulsifier is one of following kinds or a variety of: a. TWEEN Series: including polysorbas20, tween
40, polysorbate60, Tween 80 are chemically synthesized food or feed grade product;B. fatty glyceride: including monostearate
Glyceride or single bi-tristearin, are chemically synthesized food or feed grade product.
Wherein, the synergist is a kind of following or two kinds: a. citric acids, is Citric Acid Mono or anhydrous citric acid, food
Product or feed grade product;B. propylene glycol, for 1,3-PD or 1,2-PD, food or feed grade product.
Wherein, anticaking agent is feed grade silicon dioxide.
Embodiment 1
A kind of feed growth promotion oxidation-resistant compound additive, raw material ratio:
Feed grade glycocyamine, double centner;
Natural Rosmarinus officinalis extract (including Rosmarinic acid 5%, carnosic acid 5%, ursolic acid 25% etc.), 1 kilogram;
Bamboo-leaves flavones (bamboo extractive), 1 kilogram;
Natural turmeric part (turmeric cellulose content 5%), 5 kilograms;
Grape pip (moisture content < 8%), 20 kilograms;
Tea polyphenols (polyphenol content 40%), 20 kilograms;
Food-grade polysorbas20,5 kilograms;
Food-grade list tristearin glyceride, 10 kilograms;
Food-grade citric acid, 10 kilograms;
Food grade propylene glycol, 8 kilograms;
Feed grade silicon dioxide, 20 kilograms.
Preparation method:
It is spare after must crushing 1. material particles are greater than 60 mesh.In order to keep the stability of material, nitrogen guarantor can be used
It is smashed in the state of shield, it is spare after the sieving of 60 mesh.The raw material that need to be crushed has: glycocyamine, turmeric, grape pip, the list of sheet are hard
Glycerol, citric acid etc..
2. mixing step: putting into 20 kilograms of silica in mixing and blending machine, stirring is opened, and the tween of liquid is then put into
20 5 kilograms and 8 kilograms of propylene glycol, then successively 20 kilograms of tea polyphenols of investment, 1 kilogram of rosemary, 1 kilogram of bamboo-leaves flavones, turmeric
5 kilograms of powder, 20 kilograms of grape pip, 10 kilograms and 10 kilograms of citric acid of glycerin monostearate, finally put into glycocyamine 100
Kilogram, stir 5-10 minute, 60 mesh be sieved 200 kilograms of product.
This product 300-500 grams of addition per ton in mixed feed, that is, can reach the effect of 300-500 grams of pure glycocyamine
The growth-promoting effect of fruit, i.e. glycocyamine is multiplied.Highest additive amount is no more than 1000 g tons in mixed feed, excess
Increase cannot be synchronized by adding its effect.This product antioxidant effect is also fabulous.Product Safety is high, and palatability is good.In concentrated feed
Additive amount can take the circumstances into consideration to increase.
Embodiment 2
A kind of feed growth promotion oxidation-resistant compound additive, raw material ratio:
Feed grade glycocyamine, double centner;
Food or feed grade tert-butyl hydroquinone, 5 kilograms;
Food or feed grade di-t-butyl hydroxyanisole, 3 kilograms;
Food or feed grade tert-butyl hydroxy toluene, 30 kilograms;
Food-grade Tween 80,5 kilograms;
Food-grade list bi-tristearin, 10 kilograms;
Food-grade citric acid, 15 kilograms;
Food grade propylene glycol, 12 kilograms;
Feed grade silicon dioxide, 15 kilograms.
Preparation method:
1. by the preparation method of embodiment 1 1. by raw material glycocyamine, tert-butyl hydroquinone, tert-butyl hydroxy fennel
Ether, di-tert-butyl hydroxy toluene, single bi-tristearin, citric acid etc. pulverize and sieve spare after 60 mesh.
2. mixing step: first putting into 15 kilograms of silica in mixing and blending machine, Tween 80 (such as winter is added after stirring starting
When it is in paste, 40 DEG C -50 DEG C are previously heated to, viscosity can obviously reduce, in liquid) 5 kilograms, 12 kilograms of propylene glycol, then
Single 10 kilograms of bi-tristearin, 5 kilograms of tert-butyl hydroquinone, 3 kilograms of butylhydroxy anisole, two is successively added
30 kilograms and 15 kilograms of citric acid of tert-butyl hydroxy toluene, it is eventually adding glycocyamine double centner, is stirred 5-10 minutes, 60 mesh
Sieving 200 kilograms of product.
This product 300-500 grams of addition per ton in mixed feed, that is, can reach the effect of 300-500 grams of pure glycocyamine
Fruit, i.e. glycocyamine effect are multiplied.Highest additive amount is no more than 750 g tons in mixed feed.
It is intended to reach comparatively ideal antioxidant effect, this product adds (500-600) g ton in mixed feed.In concentrated feed
In can take the circumstances into consideration increase additive amount.
Embodiment 3
A kind of feed growth promotion oxidation-resistant compound additive, raw material ratio:
Feed grade glycocyamine, double centner;
Food or feed grade propylgallate, 5 kilograms;
Food or feed grade ethoxyquinoline, 15 kilograms;
Food-grade Tween 80,3 kilograms;
Food-grade citric acid, 3 kilograms;
Food grade propylene glycol, 5 kilograms;
Feed grade silicon dioxide, 70 kilograms.
Preparation method:
1. by the preparation method of embodiment 1 1. by material glycocyamine, propylgallate, citric acid, maize cob meal etc.
It crushed spare after 60 meshes.
2. mixing step: first putting into 70 kilograms of silica in mixing and blending machine, Tween 80 3,000 is added after stirring starting
Gram and 15 kilograms of ethoxyquinoline (two kinds of materials temperature lower winter be in paste, 40 DEG C -50 DEG C can be previously heated to, glue
Degree can obviously reduce, in liquid) and 5 kilograms of propylene glycol, 5 kilograms of propylgallate are then successively added, citric acid 3
Kilogram, 57 kilograms of maize cob meal, be eventually adding glycocyamine double centner stir 5-10 minute, 60 mesh be sieved product 200
Kilogram.
This product 300-500 grams of addition per ton in mixed feed, that is, can reach the effect of 300-500 grams of pure glycocyamine
Fruit, i.e. glycocyamine effect are multiplied, and highest additive amount is no more than 1200 g tons in mixed feed.
Glycocyamine and the unsuitable excess addition of antioxidant, excess adds its growth promotion and antioxidant effect is possible to anti-
And reduce, palatability and safety may also decrease.Corn, beans need to be used when concentrated feed is because being processed into mixed feed
The dilution such as dregs of rice, therefore can take the circumstances into consideration to increase additive amount.
Embodiment 4
A kind of feed growth promotion oxidation-resistant compound additive, raw material ratio:
Feed grade glycocyamine, double centner;
Feed grade tea polyphenols (polyphenol content 30%), 30 kilograms;
Food-grade or feed grade di-tert-butyl hydroxy toluene, 30 kilograms;
Food-grade list bi-tristearin, 10 kilograms;
Food-grade citric acid, 15 kilograms;
Food grade propylene glycol, 15 kilograms;
Feed grade silicon dioxide, 25 kilograms.
Preparation method:
1. the preparation method by embodiment 1 is 1. double hard by material glycocyamine, di-tert-butyl hydroxy toluene, citric acid, list
It is spare that glycerol etc. crushed 60 mesh.
2. mixing step: first putting into 25 kilograms of silica in mixing and blending machine, propylene glycol 15,000 is added after stirring starting
Gram and single 10 kilograms of bi-tristearin, 30 kilograms of tea polyphenols, 30 kilograms of di-tert-butyl hydroxy toluene are then successively added,
15 kilograms of citric acid, be eventually adding glycocyamine double centner, stir 5-10 minute, 60 mesh be sieved 225 kilograms of products.
This product 300-500 grams of addition per ton in mixed feed is close to and reaches 300-500 grams of pure glycocyamine
Effect, i.e. glycocyamine effect are multiplied, and highest additive amount is no more than 1000 g tons in mixed feed.Through related feeding
With feed antioxidant effect it is demonstrated experimentally that this product optimum addition in mixed feed is 500 g tons, additive amount in mixed feed
It increases between (500-1000) g ton, growth promotion and antioxidant effect have an increase, when additive amount is up to 2000 g tons, even
It will appear certain negative effects.Additive amount in concentrated feed can take the circumstances into consideration to increase, be diluted to concentration in mixed feed by it
It is best for 500 g tons.
In order to compare the product of the embodiment 4 progress oxidation resistant effect of growth promotion, broiler feeding experiment is carried out, now will
Various data are summarized.
Broiler chicken kind: AA white meat-type chickens have raised 18 ages in days, and average weight up to 500 grams/plumage or so, is selected from same
Batch, same farm, same cultivating condition AA chicken, this batch cultivate about 1200 plumage of number, therefore randomly choose every group wherein
200 plumages divide A, B, C, D, E five groups, and every group of male and female ratio is essentially identical.
The housing conditions of cultivation: area, daylighting, ventilation, heat preservation, illumination, henroost, pad paving, slot material of every booth etc. are homogeneous
Together, and the disinfection of booth, sterilization, epidemic prevention it is all the same.
Feeding feed stuff: the 19th starts, and the basic feed condition of 5 experimental groups is identical, answers in the mixed feed separately processed
The drug and nutriment matter of addition is all consistent, and feeding frequency is also all consistent with scale of feeding.It should be noted that not another in feed
Row addition glycine betaine or choline chloride, only have any different on growth promotion oxidation-resistant compound additive additive amount.
Experimental period: September 1 day to September 20th in 2017
AA chicken feed result comparison sheet
Note: 1. every all 500kg of test group mixed feed usage amount are fed, root after precalculating by feed ration incremental change
It has been observed that substantially without wasting phenomenon.
2. the capture generated due to changing for experimental site, resettlement and weighing etc. stress influence, second day discovery A, B,
C, respectively there are 2 plumage chickens dull for three groups, D and E respectively have found that 1 plumage death and 1 plumage are dull, and selection weight is closer to from original cultivation group
Give and exchange, it is ensured that every group is 200 plumages.Until September 20th, under conditions of managing with delicacy and raising, disease does not occur
And death.
Conclusion: 1. in administering transgenic, in addition to control group, remaining four groups obtain effect of significantly promoting production.2. effect
It is best with C and two groups of D.The reason is that D group additive amount is up to 1000mg/kg;C group additive amount is only 500mg/kg, though effect
Lower than D group, but cost reduction half is added, therefore cost performance improves;E group the result is that additive amount is too big, played negative effect.B
For group due to not operating by requirement of the invention, addition cost is slightly higher, and effect is not also significant.Comprehensive Evaluation, C group are most ideal.
In addition, the present embodiment has also carried out the anti-oxidant comparative test of feed:
Feed is customized according to the nutritional need of AA chicken, 3% soybean oil is added to, along with thick in corn-soybean meal
Fat, oil quantity should test season duration late summer, therefore can more clearly observe the oxidization condition of feed far away from 5% or more.Examination
The feed tested and production on August 25 days 24,2017, every group of production 600kg select the product of embodiment 4 respectively in C, D, E
Feed group is added when producing, compared with A and B group carries out antioxidant effect in the future.Although the acid value and peroxidating of grease in feed
Value measures roughly after can only extracting, but the data quantified for reference, but can increase manually smelly for feedstuff oil and rancidity
Smelling sense organ distinguish, to the level evaluation of five group feed oxide degree after one month, it may be determined that be correct.September 25 days
The data of measurement and the feed product of observation all obtain sample in the remaining original packing that do not break a seal in five feed groups.
Feed oxide degree comparison sheet
Conclusion: the artificial reference data for distinguishing binding assay, by storage in 31 days, A group feed had apparent oxidation;B
Group has a little oxidation;C, D and E group is better, no significant difference, and antioxidant effect is preferable.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding
And modification, the scope of the present invention is defined by the appended.
Claims (8)
1. a kind of feed growth promotion oxidation-resistant compound additive, which is characterized in that prepared by following substance by appended parts by weight
It forms: 100 parts of glycocyamine, 10-90 parts of antioxidant;5-20 parts of emulsifier;5-30 parts of synergist;15-70 parts of anticaking agent.
2. feed according to claim 1 growth promotion oxidation-resistant compound additive, it is characterised in that: the glycocyamine
For feed grade glycocyamine.
3. feed according to claim 1 growth promotion oxidation-resistant compound additive, it is characterised in that: described is anti-oxidant
Agent is one of following several groups of substances or a variety of:
A, Rosmarinus officinalis extract, including carnosic acid, carnosol, Rosmarinic acid, rosmanol and ursolic acid;
B, bamboo-leaves flavones refer to bamboo extractive;
C, turmeric refers to the rhizome of ginger tannin plant turmeric, includes the curcumin of 2%-6%;
D, grape pip, refers to the seed dried object of table grapes, wherein the polyphenoils component procyanidine contained;
E, tea polyphenols, refer to green-tea extract polyphenol mixture general name, and polyphenol content is 30% or more;
F, tert-butyl hydroquinone TBHQ is chemically synthesized food or feed grade product;
G, butylhydroxy anisole BHA is chemically synthesized food or feed grade product;
H, di-tert-butyl hydroxy toluene BHT is chemically synthesized food or feed grade product;
I, propylgallate PG is chemically synthesized food or feed grade product;
J, ethoxyquinoline EQ is chemically synthesized food or feed grade product.
4. feed according to claim 1 growth promotion oxidation-resistant compound additive, it is characterised in that: the emulsifier
For one of following kinds or a variety of:
A. TWEEN Series: being that chemically synthesized food or feed grade produce including polysorbas20, polysorbate40, polysorbate60, Tween 80
Product;
B. fatty glyceride: including glycerin monostearate or single bi-tristearin, be chemically synthesized food or
Feed grade product.
5. feed according to claim 1 growth promotion oxidation-resistant compound additive, it is characterised in that: the synergist is
It is following a kind of or two kinds:
A. citric acid, for Citric Acid Mono or anhydrous citric acid, food or feed grade product;
B. propylene glycol, for 1,3-PD or 1,2-PD, food or feed grade product.
6. feed according to claim 1 growth promotion oxidation-resistant compound additive, it is characterised in that: the anticaking agent
For feed grade silicon dioxide.
7. the preparation method of any feed growth promotion oxidation-resistant compound additive of claim 1-6, including following step
It is rapid:
A. to reach 60 mesh used above for ambient ground or fineness under nitrogen protection as required for the big raw material of particle;
B. liquid charging stock is prefabricated into powdered semi-finished product with anticaking agent silica 2.5:1 weight ratio and places respectively for use;
C. paste raw materials are slightly heated up to 45 DEG C -55 DEG C, are prefabricated into semi-finished product with b method and place for use;
D. raw material of the weight ratio less than 1% uses after being diluted to 10%-50% concentration with silica premix, in case mixing is stirred
Mix unevenness;
E. sieving, is packaged into product after various materials being sufficiently mixed uniformly;
Wherein, in production, inside is in the inertia protection of industrial nitrogen all devices, and reduction is contacted with air.
8. the application of any feed growth promotion oxidation-resistant compound additive of claim 1-6, it is characterised in that: feed
In 300-1000 grams of addition per ton.
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110664907A (en) * | 2019-10-22 | 2020-01-10 | 广州白云山宝神动物保健品有限公司 | Composition for preventing enveloped virus infection and preparation method and application thereof |
CN111034896A (en) * | 2019-12-23 | 2020-04-21 | 宜兴市天石饲料有限公司 | Composite antioxidant and preparation method thereof |
CN112369520A (en) * | 2020-11-16 | 2021-02-19 | 广东轻工职业技术学院 | Pig compound feed with antioxidant additive and preparation method thereof |
CN114831242A (en) * | 2022-04-20 | 2022-08-02 | 翁源广业清怡食品科技有限公司 | Compound antioxidant for feed and preparation method thereof |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110257075A1 (en) * | 2004-06-09 | 2011-10-20 | Thomas Gastner | Guanidino acetic acid used as an animal food additive |
CN103549198A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Broiler chicken compound feed additive without antibiotics |
CN107259148A (en) * | 2017-07-05 | 2017-10-20 | 北京四方红饲料科技有限公司 | A kind of growing-finishing pig later stage compound premix and grain |
CN108013234A (en) * | 2016-11-04 | 2018-05-11 | 李侯根 | Feed turmeric composite antioxidant and preparation method thereof |
-
2018
- 2018-10-10 CN CN201811176313.7A patent/CN109258935A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110257075A1 (en) * | 2004-06-09 | 2011-10-20 | Thomas Gastner | Guanidino acetic acid used as an animal food additive |
CN103549198A (en) * | 2013-11-05 | 2014-02-05 | 安徽科技学院 | Broiler chicken compound feed additive without antibiotics |
CN108013234A (en) * | 2016-11-04 | 2018-05-11 | 李侯根 | Feed turmeric composite antioxidant and preparation method thereof |
CN107259148A (en) * | 2017-07-05 | 2017-10-20 | 北京四方红饲料科技有限公司 | A kind of growing-finishing pig later stage compound premix and grain |
Non-Patent Citations (1)
Title |
---|
王娇等: "胍基乙酸在家禽生产中的应用", 《中国饲料》 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110664907A (en) * | 2019-10-22 | 2020-01-10 | 广州白云山宝神动物保健品有限公司 | Composition for preventing enveloped virus infection and preparation method and application thereof |
CN110664907B (en) * | 2019-10-22 | 2021-09-24 | 广州白云山宝神动物保健品有限公司 | Composition for preventing enveloped virus infection and preparation method and application thereof |
CN111034896A (en) * | 2019-12-23 | 2020-04-21 | 宜兴市天石饲料有限公司 | Composite antioxidant and preparation method thereof |
CN112369520A (en) * | 2020-11-16 | 2021-02-19 | 广东轻工职业技术学院 | Pig compound feed with antioxidant additive and preparation method thereof |
CN114831242A (en) * | 2022-04-20 | 2022-08-02 | 翁源广业清怡食品科技有限公司 | Compound antioxidant for feed and preparation method thereof |
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