CN114831242A - Compound antioxidant for feed and preparation method thereof - Google Patents
Compound antioxidant for feed and preparation method thereof Download PDFInfo
- Publication number
- CN114831242A CN114831242A CN202210417239.3A CN202210417239A CN114831242A CN 114831242 A CN114831242 A CN 114831242A CN 202210417239 A CN202210417239 A CN 202210417239A CN 114831242 A CN114831242 A CN 114831242A
- Authority
- CN
- China
- Prior art keywords
- antioxidant
- feed
- parts
- weight
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 177
- 239000003963 antioxidant agent Substances 0.000 title claims abstract description 146
- 150000001875 compounds Chemical class 0.000 title claims abstract description 34
- 238000002360 preparation method Methods 0.000 title abstract description 15
- 235000006708 antioxidants Nutrition 0.000 claims abstract description 145
- 235000005881 Calendula officinalis Nutrition 0.000 claims abstract description 35
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 claims abstract description 33
- 229930003944 flavone Natural products 0.000 claims abstract description 33
- 150000002212 flavone derivatives Chemical class 0.000 claims abstract description 33
- 235000011949 flavones Nutrition 0.000 claims abstract description 33
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 claims abstract description 33
- 239000002131 composite material Substances 0.000 claims abstract description 23
- 239000002994 raw material Substances 0.000 claims abstract description 10
- 238000000034 method Methods 0.000 claims abstract description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 46
- 241000736851 Tagetes Species 0.000 claims description 34
- 239000000203 mixture Substances 0.000 claims description 28
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 24
- 235000013824 polyphenols Nutrition 0.000 claims description 24
- 238000002156 mixing Methods 0.000 claims description 21
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 20
- 229930003268 Vitamin C Natural products 0.000 claims description 20
- 235000019154 vitamin C Nutrition 0.000 claims description 20
- 239000011718 vitamin C Substances 0.000 claims description 20
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- 229910021536 Zeolite Inorganic materials 0.000 claims description 10
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 239000010457 zeolite Substances 0.000 claims description 10
- BGNXCDMCOKJUMV-UHFFFAOYSA-N Tert-Butylhydroquinone Chemical compound CC(C)(C)C1=CC(O)=CC=C1O BGNXCDMCOKJUMV-UHFFFAOYSA-N 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 238000002844 melting Methods 0.000 claims description 7
- 239000004250 tert-Butylhydroquinone Substances 0.000 claims description 7
- 235000019281 tert-butylhydroquinone Nutrition 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 7
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 6
- ZTHYODDOHIVTJV-UHFFFAOYSA-N Propyl gallate Chemical compound CCCOC(=O)C1=CC(O)=C(O)C(O)=C1 ZTHYODDOHIVTJV-UHFFFAOYSA-N 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- 239000006229 carbon black Substances 0.000 claims description 6
- 239000002530 phenolic antioxidant Substances 0.000 claims description 4
- SPSPIUSUWPLVKD-UHFFFAOYSA-N 2,3-dibutyl-6-methylphenol Chemical compound CCCCC1=CC=C(C)C(O)=C1CCCC SPSPIUSUWPLVKD-UHFFFAOYSA-N 0.000 claims description 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims description 3
- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
- 239000011668 ascorbic acid Substances 0.000 claims description 3
- 229960005070 ascorbic acid Drugs 0.000 claims description 3
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 claims description 3
- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 3
- 235000010388 propyl gallate Nutrition 0.000 claims description 3
- 239000000473 propyl gallate Substances 0.000 claims description 3
- 229940075579 propyl gallate Drugs 0.000 claims description 3
- 244000269722 Thea sinensis Species 0.000 claims 5
- 230000000694 effects Effects 0.000 abstract description 12
- 230000002195 synergetic effect Effects 0.000 abstract description 6
- 230000008901 benefit Effects 0.000 abstract description 5
- 244000144972 livestock Species 0.000 abstract description 5
- 244000144977 poultry Species 0.000 abstract description 5
- 230000011506 response to oxidative stress Effects 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 3
- 239000003674 animal food additive Substances 0.000 abstract description 2
- 240000000785 Tagetes erecta Species 0.000 abstract 1
- 241001122767 Theaceae Species 0.000 description 18
- 238000012360 testing method Methods 0.000 description 12
- 230000003647 oxidation Effects 0.000 description 9
- 238000007254 oxidation reaction Methods 0.000 description 9
- 239000013068 control sample Substances 0.000 description 7
- 239000000523 sample Substances 0.000 description 7
- 235000021323 fish oil Nutrition 0.000 description 5
- 235000012424 soybean oil Nutrition 0.000 description 5
- 239000003549 soybean oil Substances 0.000 description 5
- 239000004258 Ethoxyquin Substances 0.000 description 4
- 238000013329 compounding Methods 0.000 description 4
- 235000019285 ethoxyquin Nutrition 0.000 description 4
- DECIPOUIJURFOJ-UHFFFAOYSA-N ethoxyquin Chemical compound N1C(C)(C)C=C(C)C2=CC(OCC)=CC=C21 DECIPOUIJURFOJ-UHFFFAOYSA-N 0.000 description 4
- 229940093500 ethoxyquin Drugs 0.000 description 4
- 239000004519 grease Substances 0.000 description 4
- 239000000969 carrier Substances 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 150000002978 peroxides Chemical class 0.000 description 3
- 235000019733 Fish meal Nutrition 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000004467 fishmeal Substances 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N quercetagetin Chemical compound C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3544—Organic compounds containing hetero rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/349—Organic compounds containing oxygen with singly-bound oxygen
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/3463—Organic compounds; Microorganisms; Enzymes
- A23L3/3481—Organic compounds containing oxygen
- A23L3/3508—Organic compounds containing oxygen containing carboxyl groups
- A23L3/3517—Carboxylic acid esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
- A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
- A23L3/358—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/90—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in food processing or handling, e.g. food conservation
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Inorganic Chemistry (AREA)
- Fodder In General (AREA)
Abstract
The invention relates to the technical field of feed additives, in particular to a compound antioxidant for feed and a preparation method thereof. The composite antioxidant for the feed comprises the following raw material components in parts by weight: 2-5 parts of marigold flavone, 10-30 parts of antioxidant and 50-80 parts of carrier. The composite antioxidant for the feed can play a synergistic effect among the antioxidants, has an obvious antioxidant effect, a strong antioxidant effect and a good antioxidant capacity maintaining effect, can relieve the oxidative stress reaction of organisms, promotes the healthy growth of livestock and poultry, and solves the problems that the existing antioxidant for the feed has a poor antioxidant effect and the antioxidant capacity is easily and quickly weakened. The prepared composite antioxidant for the feed can be contacted with the feed more fully, so that a more effective antioxidant effect is exerted, and the preparation method has the advantages of simple process and safety.
Description
Technical Field
The invention relates to the technical field of feed additives, in particular to a compound antioxidant for feed and a preparation method thereof.
Background
The feed is rich in nutrient components, is very easy to oxidize in the production, processing, transportation and storage processes, and the oxidation of the feed can cause the loss of the nutrient components of the feed, so that the palatability of the feed is reduced, the oxidative stress is stimulated, and the health state of animals is further influenced. The oxidation of the feed can be effectively avoided by adding the feed antioxidant, ethoxyquin is the most common antioxidant in the feed, has the advantages of good using effect, low price and the like, but because ethoxyquin has physiological toxicity, part of countries of European Union have banned low-content ethoxyquin, and the development of new feed antioxidant products without ethoxyquin is the trend of the current market. At present, natural antioxidant ingredients are also applied to feed antioxidants, but the antioxidant which singly uses the natural antioxidant ingredients has poor antioxidant effect, and the antioxidant capacity is easy to quickly weaken, so that the antioxidant effect applied to the feed is not obvious.
Disclosure of Invention
Aiming at the problems brought forward by the background technology, the invention aims to provide a compound antioxidant for feed, which can play a role in synergy among antioxidants, has remarkable antioxidant effect, strong antioxidant effect and good antioxidant capacity maintaining effect, can relieve the oxidative stress reaction of organisms, promotes the healthy growth of livestock and poultry, and solves the problems that the existing antioxidant for feed has poor antioxidant effect and the antioxidant capacity is easy to weaken quickly.
The invention also aims to provide a preparation method of the compound antioxidant for the feed, the prepared compound antioxidant for the feed can be contacted with the feed more fully, so that the more effective antioxidant effect is exerted, and the preparation method has the advantages of simple process and safety.
In order to achieve the purpose, the invention adopts the following technical scheme:
the composite antioxidant for the feed comprises the following raw material components in parts by weight:
2-5 parts of marigold flavone
10-30 parts of antioxidant
50-80 parts of a carrier.
Further, the feed also comprises the following raw material components in parts by weight:
2-5 parts of tea polyphenol
4-10 parts of vitamin C.
Further, the weight ratio of the total weight of the marigold flavone and the tea polyphenol to the vitamin C is 1: 1.
further, the weight ratio of the total weight of the marigold flavone and the tea polyphenol to the antioxidant is 1: 3.
still further, the antioxidant is a phenolic antioxidant, and the antioxidant is selected from any one or more of tert-butyl hydroquinone, butyl hydroxy anisole, dibutyl hydroxy toluene and propyl gallate.
Further, the feed also comprises the following raw material components in parts by weight: 1-5 parts of a synergist.
Still further, the synergist is selected from any one or more of citric acid, phosphoric acid and ascorbic acid.
Still further, the carrier is selected from any one or a combination of two of zeolite powder and white carbon black.
A preparation method of a compound antioxidant for feed is used for preparing the compound antioxidant for feed, and comprises the following steps:
(1) weighing marigold flavone, an antioxidant, a carrier, tea polyphenol, vitamin C and a synergist according to parts by weight;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 60-80 ℃, and uniformly mixing the antioxidant with 70% by weight of the carrier in the step (2) to obtain a mixture A;
(4) uniformly mixing marigold flavone, tea polyphenol, vitamin C and a synergist with the carrier with the weight percentage of 30% in the step (2) to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
Compared with the prior art, the embodiment of the invention has the following beneficial effects:
the antioxidant effect of the antioxidant can be greatly improved by using the natural antioxidant and the artificially synthesized antioxidant in a compounding way, the synergistic effect of the antioxidant effect of 1+1 & gt 2 can be achieved under the condition of less antioxidant using amount, in addition, the artificial antioxidant and the natural marigold flavone in a compounding way have good maintaining effect of antioxidant capacity and are not easy to be oxidized by air, and the in-vitro and in-vivo double-effect antioxidant effect can be achieved. The oxidation resistance is easy to be rapidly weakened;
the composite antioxidant for the feed prepared by the preparation method of the composite antioxidant for the feed can be used in products such as feed, premix, concentrate, grease for feed, fish meal and the like, and has excellent antioxidant effect.
Detailed Description
The composite antioxidant for the feed comprises the following raw material components in parts by weight:
2-5 parts of marigold flavone
10-30 parts of antioxidant
50-80 parts of a carrier.
Marigold flavone is a natural substance extracted from marigold, has the effects of resisting oxidation, inflammation, allergy, blood pressure, arrhythmia, tumor and the like, is a natural antioxidant, has good antioxidant effect, can effectively inhibit the oxidative stress reaction of organisms when used in livestock and poultry, and has the effects of promoting the growth of the livestock and poultry and reducing the feed conversion ratio. The antioxidant effect of the antioxidant can be greatly improved by using the natural antioxidant and the artificially synthesized antioxidant in a compounding way, the synergistic effect of the antioxidant effect of 1+1 > 2 can be achieved under the condition of less antioxidant using amount, in addition, the antioxidant capacity is well kept by using the artificial antioxidant and the natural marigold flavone in a compounding way, the antioxidant is not easily oxidized by air, and the in-vitro and in-vivo double-effect antioxidant effect can be achieved.
The compound antioxidant for the feed can play a synergistic effect among the antioxidants, has an obvious antioxidant effect, a strong antioxidant effect and a good maintaining effect of antioxidant capacity, improves the antioxidant effect of the compound antioxidant on the feed and feed grease products on the one hand, and can relieve the oxidative stress reaction of organisms and promote the healthy growth of livestock and poultry on the other hand due to the addition of marigold flavone, has the advantage of low production cost, and solves the problems that the existing antioxidant for the feed has a poor antioxidant effect and the antioxidant capacity is easily and quickly weakened.
Further, the feed also comprises the following raw material components in parts by weight:
2-5 parts of tea polyphenol
4-10 parts of vitamin C.
Tea polyphenol is a natural antioxidant, has the biological activity effects of natural oxidation resistance, inflammation resistance, antibiosis, blood sugar and lipid reduction, regulation of intestinal flora and the like, can effectively remove free radicals in vivo to achieve the effect of oxidation resistance, can effectively improve the oxidation resistance of the compound antioxidant by cooperating with marigold flavone, and in addition, by adding vitamin C, the vitamin C has stronger oxidation resistance, and can play a role of synergy by cooperating with the tea polyphenol and the marigold flavone which are used as the natural antioxidant, thereby further enhancing the oxidation resistance of the compound antioxidant for feed.
Preferably, the weight ratio of the total weight of the marigold flavone and the tea polyphenol to the vitamin C is 1: 1.
preferably, the content of quercetagetin in the marigold flavonoids is more than or equal to 50 percent according to the mass percentage, the antioxidant activity is strong, and the antioxidant effect is good.
More specifically, the weight ratio of the total weight of the marigold flavone and the tea polyphenol to the vitamin C is preferably 1: 1, the vitamin C can play the best synergistic effect by matching with the tea polyphenol and the marigold flavone, and the antioxidant effect of the compound antioxidant is strong in the proportion.
Preferably, the weight ratio of the total weight of the marigold flavone and the tea polyphenol to the antioxidant is 1: 3.
the composite antioxidant for the feed has the advantages that the two natural antioxidants of the tea polyphenol and the marigold flavone are used and are matched with the artificially synthesized antioxidant, the antioxidant effect is obvious, the composite antioxidant for the feed is compounded by using a plurality of antioxidants, the proportion is reasonable, and the synergistic effect of the antioxidants can be exerted to the maximum extent.
Still further, the antioxidant is a phenolic antioxidant, and the antioxidant is selected from any one or more of tert-butyl hydroquinone, butyl hydroxy anisole, dibutyl hydroxy toluene and propyl gallate.
The phenolic antioxidant has the characteristics of excellent antioxidant effect and safe use, is widely applied to edible oil and food, has good protection effect on feeding grease and feed, and is the best product for replacing ethoxyquinoline in the current market.
Further, the feed also comprises the following raw material components in parts by weight: 1-5 parts of a synergist.
By adding the synergist, the antioxidant effect of the antioxidant can be effectively enhanced, and the antioxidant effect of the composite antioxidant for feed is improved, so that the antioxidant effect of the composite antioxidant for feed in feed is more remarkable.
Preferably, the synergist is selected from any one or combination of more of citric acid, phosphoric acid and ascorbic acid.
The synergist can effectively improve the antioxidant effect of the compound antioxidant for the feed, wherein citric acid is an excellent antioxidant and can further enhance the antioxidant effect of the compound antioxidant.
Preferably, the carrier is selected from any one or a combination of two of zeolite powder and white carbon black.
The zeolite powder and the white carbon black are selected as carriers, both the zeolite powder and the white carbon black have larger specific surface areas, so that the zeolite powder and the white carbon black have stronger adsorption capacity and good dispersibility, are good carriers of trace element additives, and are selected as carriers of additive premixes, so that the loading effect is good, and the antioxidant effect of active ingredients in the composite antioxidant for the feed is ensured.
A preparation method of a compound antioxidant for feed is used for preparing the compound antioxidant for feed, and comprises the following steps:
(1) weighing marigold flavone, an antioxidant, a carrier, tea polyphenol, vitamin C and a synergist according to parts by weight;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 60-80 ℃, and then uniformly mixing the antioxidant with 70 wt% of the carrier in the step (2) to obtain a mixture A;
(4) uniformly mixing marigold flavone, tea polyphenol, vitamin C and a synergist with the carrier with the weight percentage of 30% in the step (2) to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
The invention firstly heats and melts the antioxidant and then mixes the antioxidant with part of the carrier, so that the antioxidant and the carrier are mutually permeated and fully and uniformly mixed together.
The composite antioxidant for the feed prepared by the preparation method can be used in products such as feed, premix, concentrated feed, feed grease, fish meal and the like, and when the composite antioxidant for the feed is applied to the feed, the addition amount of the composite antioxidant for the feed is 200-400 mg/kg of basic ration, and a relatively small amount of the composite antioxidant for the feed can achieve a relatively good antioxidant effect.
In order to facilitate an understanding of the present invention, a more complete description of the present invention is provided below. The present invention may be embodied in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
The examples, where specific techniques or conditions are not indicated, are to be construed according to the techniques or conditions described in the literature in the art or according to the product specifications. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products commercially available.
Example 1
A preparation method of a compound antioxidant for feed comprises the following steps:
(1) weighing 2 parts of marigold flavone, 10 parts of antioxidant and 50 parts of carrier according to parts by weight, wherein the antioxidant is tert-butyl hydroquinone, and the carrier is zeolite powder;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 70 ℃, and uniformly mixing the antioxidant with 70% of the carrier in the step (2) by weight to obtain a mixture A;
(4) uniformly mixing marigold flavone with 30% of the carrier in the step (2) by weight to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
Example 2
A preparation method of a compound antioxidant for feed comprises the following steps:
(1) weighing 5 parts of marigold flavone, 30 parts of antioxidant and 80 parts of carrier according to parts by weight, wherein the antioxidant is tert-butylhydroquinone, and the carrier is zeolite powder;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 70 ℃, and uniformly mixing the antioxidant with 70% of the carrier in the step (2) by weight to obtain a mixture A;
(4) uniformly mixing marigold flavone with 30% of the carrier in the step (2) by weight to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
Example 3
A preparation method of a compound antioxidant for feed comprises the following steps:
(1) weighing 3 parts of marigold flavone, 18 parts of antioxidant, 70 parts of carrier, 3 parts of tea polyphenol and 6 parts of vitamin C according to parts by weight, wherein the antioxidant is tert-butyl hydroquinone, and the carrier is zeolite powder;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 70 ℃, and uniformly mixing the antioxidant with 70% of the carrier in the step (2) by weight to obtain a mixture A;
(4) uniformly mixing marigold flavone, tea polyphenol and vitamin C with the carrier of which the weight is 30% in the step (2) to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
Example 4
A preparation method of a compound antioxidant for feed comprises the following steps:
(1) weighing 3 parts of marigold flavone, 18 parts of antioxidant, 70 parts of carrier, 3 parts of tea polyphenol, 6 parts of vitamin C and 2 parts of synergist according to parts by weight, wherein the antioxidant is tert-butylhydroquinone, the carrier is zeolite powder, and the synergist is citric acid;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 70 ℃, and uniformly mixing the antioxidant with 70% of the carrier in the step (2) by weight to obtain a mixture A;
(4) uniformly mixing marigold flavone, tea polyphenol, vitamin C and a synergist with the carrier with the weight percentage of 30% in the step (2) to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
And (3) testing the antioxidant effect:
using commercially conventional feed, soybean oil and fish oil, six groups of samples were set, wherein three groups were set as a feed blank control sample, a fish oil blank control sample and a soybean oil blank control sample (the blank control sample was not added with an antioxidant), and the other three groups were set as a feed test sample, a fish oil test sample and a soybean oil test sample (the test sample was added with the compound antioxidant for feed prepared in example 1, the addition amount of the compound antioxidant for feed was 300mg/kg, and the effective component of the compound antioxidant for feed was 60%), the three groups of blank control samples and the three groups of test samples were stored at 40 ℃, peroxide values were measured once per week, and the test results are shown in table 1 below:
TABLE 1 test results of antioxidant Effect
From the test results, the peroxide values of the feed blank control sample, the fish oil blank control sample and the soybean oil blank control sample are rapidly increased along with the storage time, and after the composite antioxidant for feed is added, the peroxide values of the feed test sample, the fish oil test sample and the soybean oil test sample are slowly increased, so that the composite antioxidant for feed prepared by the invention has good antioxidant effect and good antioxidant capacity maintaining effect, and can achieve better antioxidant effect only by adding a small amount of the composite antioxidant for feed prepared by the invention into basic daily ration.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (9)
1. The composite antioxidant for the feed is characterized by comprising the following raw material components in parts by weight:
2-5 parts of marigold flavone
10-30 parts of antioxidant
50-80 parts of a carrier.
2. The compound antioxidant for feed as claimed in claim 1, further comprising the following raw material components in parts by weight:
2-5 parts of tea polyphenol
4-10 parts of vitamin C.
3. The complex antioxidant for feed as claimed in claim 2, wherein the weight ratio of the total weight of marigold flavone and tea polyphenol to the vitamin C is 1: 1.
4. the complex antioxidant for feed as claimed in claim 2, wherein the weight ratio of the total weight of marigold flavone and tea polyphenol to the antioxidant is 1: 3.
5. the complex antioxidant for feed as claimed in claim 2, wherein the antioxidant is a phenolic antioxidant, and the antioxidant is selected from the group consisting of tert-butylhydroquinone, butylhydroxyanisole, dibutylhydroxytoluene, and propyl gallate.
6. The compound antioxidant for feed as claimed in claim 2, further comprising the following raw material components in parts by weight: 1-5 parts of a synergist.
7. The complex antioxidant for feedstuff as claimed in claim 6, wherein the synergist is selected from one or more of citric acid, phosphoric acid and ascorbic acid.
8. The composite antioxidant for feed as claimed in claim 1, wherein the carrier is selected from one or a combination of two of zeolite powder and white carbon black.
9. A method for preparing the composite antioxidant for feed, which is used for preparing the composite antioxidant for feed as claimed in any one of claims 6 to 7, and comprises the following steps:
(1) weighing marigold flavone, an antioxidant, a carrier, tea polyphenol, vitamin C and a synergist according to parts by weight;
(2) dividing the carrier weighed in the step (1) into two parts according to 70% and 30% by weight;
(3) heating and hot-melting an antioxidant at 60-80 ℃, and uniformly mixing the antioxidant with 70% by weight of the carrier in the step (2) to obtain a mixture A;
(4) uniformly mixing marigold flavone, tea polyphenol, vitamin C and a synergist with the carrier with the weight percentage of 30% in the step (2) to obtain a mixture B;
(5) and uniformly mixing the mixture A and the mixture B to obtain the compound antioxidant for the feed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210417239.3A CN114831242A (en) | 2022-04-20 | 2022-04-20 | Compound antioxidant for feed and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210417239.3A CN114831242A (en) | 2022-04-20 | 2022-04-20 | Compound antioxidant for feed and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114831242A true CN114831242A (en) | 2022-08-02 |
Family
ID=82565925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210417239.3A Pending CN114831242A (en) | 2022-04-20 | 2022-04-20 | Compound antioxidant for feed and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114831242A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113117A (en) * | 1995-04-25 | 1995-12-13 | 李侯根 | Composite oxidation preventive for fodder and its production method |
| CN101095460A (en) * | 2006-06-28 | 2008-01-02 | 李侯根 | Tea polyphenol composite antioxidant for feedstuff and method for preparing the same |
| CN102308915A (en) * | 2011-07-26 | 2012-01-11 | 上海交通大学 | Anti-oxidant composition for improving animal immune function and preparation method thereof |
| CN102318742A (en) * | 2011-08-26 | 2012-01-18 | 上海交通大学 | Antioxidant health care egg production method and composite antioxidant used by same |
| CN107373093A (en) * | 2017-06-21 | 2017-11-24 | 宜兴市天石饲料有限公司 | A kind of oil-free composite antioxidant and preparation method thereof |
| CN107996834A (en) * | 2017-11-30 | 2018-05-08 | 味氏（广东）生物科技股份有限公司 | Feed addictive, its preparation method and include its feed |
| CN109258935A (en) * | 2018-10-10 | 2019-01-25 | 江苏奥迈生物科技有限公司 | Feed growth promotion oxidation-resistant compound additive and its preparation method and application |
| CN110250394A (en) * | 2019-06-04 | 2019-09-20 | 广东省农业科学院动物科学研究所 | A kind of feed composite antioxidant and preparation method thereof |
| CN113749206A (en) * | 2020-06-02 | 2021-12-07 | 晨光生物科技集团股份有限公司 | Oil-soluble marigold flavone preparation and preparation method and application thereof |
-
2022
- 2022-04-20 CN CN202210417239.3A patent/CN114831242A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1113117A (en) * | 1995-04-25 | 1995-12-13 | 李侯根 | Composite oxidation preventive for fodder and its production method |
| CN101095460A (en) * | 2006-06-28 | 2008-01-02 | 李侯根 | Tea polyphenol composite antioxidant for feedstuff and method for preparing the same |
| CN102308915A (en) * | 2011-07-26 | 2012-01-11 | 上海交通大学 | Anti-oxidant composition for improving animal immune function and preparation method thereof |
| CN102318742A (en) * | 2011-08-26 | 2012-01-18 | 上海交通大学 | Antioxidant health care egg production method and composite antioxidant used by same |
| CN107373093A (en) * | 2017-06-21 | 2017-11-24 | 宜兴市天石饲料有限公司 | A kind of oil-free composite antioxidant and preparation method thereof |
| CN107996834A (en) * | 2017-11-30 | 2018-05-08 | 味氏（广东）生物科技股份有限公司 | Feed addictive, its preparation method and include its feed |
| CN109258935A (en) * | 2018-10-10 | 2019-01-25 | 江苏奥迈生物科技有限公司 | Feed growth promotion oxidation-resistant compound additive and its preparation method and application |
| CN110250394A (en) * | 2019-06-04 | 2019-09-20 | 广东省农业科学院动物科学研究所 | A kind of feed composite antioxidant and preparation method thereof |
| CN113749206A (en) * | 2020-06-02 | 2021-12-07 | 晨光生物科技集团股份有限公司 | Oil-soluble marigold flavone preparation and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Valenti et al. | Effect of different dietary tannin extracts on lamb growth performances and meat oxidative stability: Comparison between mimosa, chestnut and tara | |
| CN101095460B (en) | Tea polyphenol composite antioxidant for feedstuff and method for preparing the same | |
| CN105124176A (en) | Compounded feed of improving anti-oxidizing activity of pork | |
| Ipek et al. | Effects of humic acid on some hematological parameters, total antioxidant capacity and laying performance in Japanese quails | |
| CN109258935A (en) | Feed growth promotion oxidation-resistant compound additive and its preparation method and application | |
| Li et al. | Comparison of chelated zinc and zinc sulfate as zinc sources for growth and bone mineralization of channel catfish (Ictalurus punctatus) fed practical diets | |
| Al-Bazy et al. | Impact of feeds containing optifeed®, vêo® premium, and oleobiotec® on the lipid peroxidation of male broilers under heat stress | |
| KR20110134194A (en) | Functional enhanced feed to produce the black pig meat by using herbs | |
| CN104824371A (en) | Novel liquid antioxidant and preparation method thereof | |
| EP0581926A1 (en) | Animal feedstuff for growth increase. | |
| AU2014257626B2 (en) | Method for improving mineral resorption in farmed fish and crustacean | |
| Sharifi et al. | The effect of grapeseed oil on performance, rumen fermentation, antioxidant status and subcutaneous adipose fatty acid profile in lambs | |
| CN114831242A (en) | Compound antioxidant for feed and preparation method thereof | |
| Mašek et al. | The influence of the addition of thymol, tannic acid or gallic acid to broiler diet on growth performance, serum malondialdehyde value and cecal fermentation. | |
| KR101358036B1 (en) | method for manufacturing a ferment feeds including Japanese Lacquer | |
| Hou et al. | Effects of dietary supplement of mulberry leaf (Morus alba) on growth and meat quality in rabbits | |
| CN108887489A (en) | A kind of mutton sheep Ration Compound method producing functional mutton | |
| CN106804947A (en) | Application of the Nobiletin in the feed addictive for improving meat quality is prepared | |
| Soliva et al. | Ruminal fermentation of mixed diets supplemented with St. John’s Wort (Hypericum perforatum) flowers and pine (Pinus mugo) oil or mixtures containing these preparations | |
| CN111919967A (en) | Premix for removing free radicals in livestock and poultry bodies and preparation method and application thereof | |
| Sugiharto | Fermented leaves in broiler rations: Effects on growth performance, physiological condition, and meat characteristics | |
| CN111513199A (en) | Pig feed additive and preparation method and application thereof | |
| CN110115321A (en) | A kind of fermentation pannage and preparation method thereof | |
| CN109907165A (en) | One boar food and preparation method thereof | |
| CN112205538B (en) | Compound feed additive for preventing occurrence of fatty liver bleeding plaques of Langder geese |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |