CN114062067A - Sample incubation device and sample analyzer - Google Patents
Sample incubation device and sample analyzer Download PDFInfo
- Publication number
- CN114062067A CN114062067A CN202010753020.1A CN202010753020A CN114062067A CN 114062067 A CN114062067 A CN 114062067A CN 202010753020 A CN202010753020 A CN 202010753020A CN 114062067 A CN114062067 A CN 114062067A
- Authority
- CN
- China
- Prior art keywords
- sample
- incubation
- plate
- bottom plate
- heat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000011534 incubation Methods 0.000 title claims abstract description 111
- 230000005540 biological transmission Effects 0.000 claims abstract description 31
- 238000010438 heat treatment Methods 0.000 claims description 16
- 230000001360 synchronised effect Effects 0.000 claims description 15
- 230000003287 optical effect Effects 0.000 claims description 10
- 230000004308 accommodation Effects 0.000 claims description 9
- 238000009434 installation Methods 0.000 claims description 5
- 239000004020 conductor Substances 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000004458 analytical method Methods 0.000 abstract description 4
- 239000000523 sample Substances 0.000 description 64
- 238000010586 diagram Methods 0.000 description 3
- 230000012447 hatching Effects 0.000 description 3
- 229930040373 Paraformaldehyde Natural products 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920006324 polyoxymethylene Polymers 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 229920001342 Bakelite® Polymers 0.000 description 1
- -1 Polyoxymethylene Polymers 0.000 description 1
- 239000004676 acrylonitrile butadiene styrene Substances 0.000 description 1
- 239000004637 bakelite Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Abstract
The application discloses device and sample analysis appearance are hatched to sample, wherein, this sample is hatched the device and is applied to sample analysis appearance, sample analysis appearance includes a bottom plate, the sample is hatched the device and is included: the incubation mechanism is arranged on the bottom plate, is arranged at intervals with the bottom plate, is used for incubating samples, and comprises an incubation disc used for bearing the samples to be tested; the power mechanism is arranged on the bottom plate and used for providing power; the transmission mechanism is respectively connected with the incubation mechanism and the power mechanism and is used for receiving power provided by the power mechanism so as to drive the incubation disc to rotate; the connecting part of the transmission mechanism and the power mechanism is arranged between the bottom plate and the incubation mechanism, and the distance from the transmission mechanism to the incubation disc is not more than the distance from the transmission mechanism to the bottom plate. Through the mode, the stability of device is hatched to sample can be improved to this application to reduce the cost of device operation to a certain extent.
Description
Technical Field
The application relates to the technical field of medical equipment, in particular to a sample incubation device and a sample analyzer.
Background
A sample analyzer is an apparatus for analyzing data of a biological sample such as blood or urine in medical care.
To meet the requirement of functionality, the devices inside the current sample analyzer are generally complex, and the weight and volume of some devices are large, thereby affecting the stability and cost of the analyzer to some extent.
Disclosure of Invention
The main technical problem who solves of this application provides a device and sample analysis appearance are hatched to sample, can improve the stability that the device was hatched to the sample to reduce the cost of device operation to a certain extent.
In order to solve the technical problem, the application adopts a technical scheme that: the utility model provides a device is hatched to sample, is applied to sample analyzer, sample analyzer includes a bottom plate to have an accommodation space and with the installing port of accommodation space intercommunication, the device is hatched to sample sets up in the accommodation space, and install on the bottom plate, the installing port is located one side that deviates from the bottom plate of hatching the device, the device is hatched to sample includes: the incubation mechanism is arranged on the bottom plate, is arranged at intervals with the bottom plate, is used for incubating samples, and comprises an incubation disc used for bearing the samples to be tested; the power mechanism is arranged on the bottom plate and used for providing power; the transmission mechanism is respectively connected with the incubation mechanism and the power mechanism and is used for receiving power provided by the power mechanism so as to drive the incubation disc to rotate; the connecting part of the transmission mechanism and the power mechanism is arranged between the bottom plate and the incubation mechanism, and the distance from the transmission mechanism to the incubation disc is not more than the distance from the transmission mechanism to the bottom plate.
In order to solve the above technical problem, another technical solution adopted by the present application is: there is provided a sample analyzer comprising: a base plate; a sample incubation device mounted on the base plate, wherein the sample incubation device is as described above.
The beneficial effect of this application is: be different from prior art's condition, this application sample is hatched the device and is applied from sample analyzer including hatching the mechanism, and this sample analyzer includes a bottom plate to have an accommodation space and with the installing port of this accommodation space intercommunication, this sample is hatched the device and is set up in the accommodation space, and install on the bottom plate, the installing port is located one side that deviates from the bottom plate of hatching the device, and this sample is hatched the device and is included: the incubation mechanism is arranged on the bottom plate, is arranged at intervals with the bottom plate, is used for incubating samples, and comprises an incubation disc used for bearing the samples to be tested; the power mechanism is arranged on the bottom plate and used for providing power; the transmission mechanism is respectively connected with the incubation mechanism and the power mechanism and is used for receiving power provided by the power mechanism so as to drive the incubation disc to rotate; the connecting part of the transmission mechanism and the power mechanism is arranged between the bottom plate and the incubation mechanism, and the distance from the transmission mechanism to the incubation disc is not more than the distance from the incubation disc to the bottom plate. In the above mode, the junction of drive mechanism and power unit sets up in the bottom plate and incubates between the mechanism, and the distance to incubating the dish is not more than the distance to the bottom plate to can reduce drive mechanism's moment of inertia, reduce the power that needs, improve the stability that the device was incubated to the sample, and reduce the cost that the device operated to a certain extent.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts. Wherein:
FIG. 1 is a schematic block diagram of an embodiment of a sample analyzer according to the present application;
FIG. 2 is a schematic structural diagram of an embodiment of a sample incubation device according to the present application;
FIG. 3 is a schematic partial view of one embodiment of a sample incubation device according to the present disclosure;
FIG. 4 is a schematic partial view of one embodiment of a sample incubation device of the present application;
FIG. 5 is a schematic partial structure view of an embodiment of a sample incubation device according to the present application.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a sample analyzer according to the present application. In the present embodiment, the sample analyzer may be a fluorescence immunoassay analyzer, a blood cell detection instrument, or the like, and is not limited herein.
The sample analyzer may include a sample incubation device 100, a bottom plate 200, and a receiving space 300 and a mounting opening 400 communicating with the receiving space 300. The sample incubation device 100 is disposed in the accommodating space 300 and is mounted on the bottom plate 200. When the operator attaches, detaches, and maintains the sample incubation device 100, the operator can operate the sample incubation device through the attachment port 400.
Further, referring to fig. 2, in one embodiment, the sample incubation device 100 may include an incubation mechanism 10, a power mechanism 30, and a transmission mechanism 20.
The incubation mechanism 10 may be mounted on the bottom plate 200 and spaced apart from the bottom plate 200 for storing and incubating samples. Specifically, the incubation mechanism 10 can be fixedly mounted on the base plate 200 by a mounting structure, or can be detachably mounted on the base plate 200 and spaced from the base plate 200 by the mounting structure. The incubation mechanism 10 can provide an environment suitable for incubating the sample, such as a temperature environment, a closed environment, and the like. In particular, the incubation mechanism 10 may comprise an incubation tray 11 for carrying and incubating the sample to be tested. It should be noted that the incubation tray 11 can be rotated under the drive of the sample incubation device during the actual operation of the device to meet different operation requirements.
The power mechanism 30 may also be mounted to the base plate 200 by a corresponding mounting structure and is used to provide power for rotating the incubation plate 11. The power mechanism 30 may be a motor, and may generate power when energized.
The transmission mechanism 20 may be respectively connected to the incubation mechanism 10 and the power mechanism 30, and is configured to receive power provided by the power mechanism 30 to rotate, so as to drive the incubation plate 11 to rotate. The transmission mechanism 20 may be composed of a gear, a shaft, a bearing, and other devices having a transmission function, and may be specifically selected according to actual needs, which is not limited herein.
It should be noted that the power mechanism 30 transmits power to the transmission mechanism 20 at the connection between the transmission mechanism 20 and the power mechanism 30, and the farther the connection between the transmission mechanism 20 and the power mechanism 30 is from the incubation disc 11, the larger the moment of inertia is, the more power the power mechanism 30 needs to provide, which is not favorable for the stability of the whole sample incubation device 100 and may increase the operation cost of the device to some extent.
In the present embodiment, the connection between the transmission mechanism 20 and the power mechanism 30 is disposed between the bottom plate 200 and the incubation mechanism 10, and the distance from the incubation plate 11 is not greater than the distance from the bottom plate 200, so as to reduce the rotational inertia of the transmission mechanism 20, reduce the required power, improve the stability of the sample incubation device 100, and reduce the operation cost of the device to a certain extent.
Specifically, in one embodiment, the transmission mechanism 20 may include a timing pulley 21 and a rotating shaft 22. One end of the rotary shaft 22 is connected to the incubation plate 11, and the other end is connected to the timing pulley 21.
Further, the power mechanism 30 may include a driving wheel 31 and a transmission belt 32. The driving belt 32 can connect the driving wheel 31 and the synchronous pulley 21 respectively to drive the synchronous pulley 21 to rotate along with the driving wheel 31, and further drive the incubation plate 11 to rotate through the rotating shaft 22.
In the related art, the power mechanism 30 and the synchronous pulley 21 are disposed close to the bottom plate 200, so that the axial distance from the synchronous pulley 21 to the incubation plate 11 is much greater than the axial distance to the bottom plate 200, and in addition, since the axial distance from the synchronous pulley 21 to the incubation plate 11 is equal to the axial size of the rotating shaft 22, the weight and the volume of the rotating shaft 22 are increased, and the moment of inertia of the rotating shaft 22 is also greatly increased.
In the present embodiment, the axial distance from the synchronous pulley 21 to the incubation plate 11 is not greater than the axial distance from the synchronous pulley 21 to the bottom plate 200, that is, the axial dimension of the rotating shaft 22, that is, the length of the rotating shaft, is relatively short, so that the weight of the rotating shaft 22 can be reduced, the volume can be reduced, the moment of inertia of the rotating shaft 22 can be reduced, and the stability of the apparatus can be improved.
Further, referring to fig. 3, in one embodiment, the rotating shaft 22 has an axially through mounting channel 221 therein, and the sample incubation device 100 further includes a fixing shaft 40, one end of the fixing shaft 40 is fixed on the bottom plate 200, and the other end far from the bottom plate 200 is disposed in the mounting channel 221.
In the present embodiment, the transmission mechanism 20 may further include a first rotation bearing 23 and a second rotation bearing 24. The first rotating bearing 23 and the second rotating bearing 24 may be disposed in the mounting channel 221 at an interval, a bearing retainer ring may be disposed between the two, inner rings of the two are all sleeved and mounted on the periphery of the fixing shaft 40, and outer rings are all abutted against the inner sidewall of the mounting channel 221, so that the rotating shaft 22 is driven by the power mechanism 30 to rotate relative to the fixing shaft 40.
Wherein, the inner ring and the outer ring of the first rotary bearing 23 and the second rotary bearing 24 can respectively correspond to the inner sidewall of the installation channel 221 of the rotating shaft 22 and the outer sidewall of the fixed shaft 40 located in the installation channel 221 in an interference fit manner, so as to further fix the rotating shaft 22 in the axial direction, thereby improving the stability of the transmission mechanism 20.
Further, referring to fig. 4, in one embodiment, the incubation mechanism 10 may include a housing 12 and a cover 13.
The housing 12 has a receiving groove 121, and a first opening 122 and a second opening 123 communicated with the receiving groove 121, wherein the first opening 122 is located on a side of the housing 12 away from the bottom plate 200, and the second opening 123 is located on a side of the housing 12 facing the bottom plate 200.
The material of the housing 12 may be bakelite which is not easy to conduct heat, and the accommodating groove 121 may be an inverted U-shaped groove with an opening facing the bottom plate 200, or may be configured in other shapes as required.
The cover 13 may cover the first opening 122 and may be further detachably mounted at the first opening 122 by a mounting structure such as a pin. The incubation disc 11 is located in the containing groove 121 and covers the second opening 123, and one end of the rotating shaft 22 away from the synchronous pulley 21 is connected with the incubation disc 11 at the second opening 123.
Further, the sample incubation apparatus 100 further includes a support shaft 50, wherein one end of the support shaft 50 is connected to the housing 12, and the other end is connected to the base plate 200, thereby mounting the housing 12 on the base plate 200. The number of the supporting shafts 50 may be one or more, for example, three supporting shafts 50 are arranged in parallel and spaced apart, and jointly support the housing 12 of the incubation mechanism 10.
Referring to fig. 5, in one embodiment, the incubation plate 11 may include a connection plate 111, a support plate 112 and a plurality of accommodating tubes 113.
The connecting plate 111 covers the second opening 123 at one side of the accommodating groove 121, and can be connected to one end of the rotating shaft 22 away from the synchronous pulley 21, so that the rotating shaft 22 can drive the whole incubation disc 11 to rotate through the connecting plate 111. The supporting plate 112 may be spaced apart from the connecting plate 111 and located at a side of the connecting plate 111 facing the base plate 200. A plurality of receiving tubes 113 may be disposed between the connecting plate 111 and the supporting plate 112.
The connecting plate 111 has a plurality of positioning holes 1111 spaced from each other, and the plurality of positioning holes 1111 and the plurality of accommodating tubes 113 have a one-to-one correspondence relationship. Each of the receiving tubes 113 has a receiving tube 113 with two open ends, one end of the receiving tube is connected to the connecting plate 111 and surrounds the corresponding positioning hole 1111 to communicate with the corresponding positioning hole 1111, and the other end of the receiving tube abuts against the supporting plate 112.
The sample incubation device 100 has a sample container 500 for accommodating a sample to be incubated in the incubation mechanism 10, and may be a test tube, a reaction cup, or the like. In this embodiment, the sample container 500 can be received in the space defined by the positioning hole 1111 and the receiving tube 113 through the corresponding positioning hole 1111, and placed on the supporting plate 112.
After the sample holder 500 is placed in the accommodating tube 113, a certain gap may exist between the outer sidewall of the sample holder 500 and the inner sidewall of the accommodating tube 113. Further, the diameter of the positioning hole 1111 may be slightly larger than the outer diameter of the sample container 500, so as to not affect the smooth placement of the sample container 500, and limit the offset of the sample container 500 from the center of the positioning hole 1111; moreover, the side wall of the positioning hole 1111 may be designed with a chamfer so as to guide the correspondingly placed sample container 500.
Further, in one embodiment, the connecting plate 111 has a receiving groove 1112 on a side facing the bottom plate 200, and the incubation tray 11 may further include a heating element 114, a heat-conducting plate 115, and a heat-conducting column 116.
The heating element 114 may be disposed in the receiving groove 1112 for generating heat. The heat conducting plate 115 may cover the accommodating groove 1112 to seal the accommodating groove 1112 and be connected to the heating member 114, so as to conduct and diffuse heat generated by the heating member 114.
The heat-conducting column 116 may be disposed between the heat-conducting plate 115 and the supporting plate 112, and one end of the heat-conducting column is connected to the heat-conducting plate 115, and the other end of the heat-conducting column is connected to the supporting plate 112 for further conducting the heat conducted by the heat-conducting plate 115. The number of the heat conduction columns 116 may be one or more, and may be specifically set according to the size of the whole incubation disc 11.
In this embodiment, the heat conducting plate 115, the heat conducting pillar 116, the supporting plate 112 and the accommodating tube 113 all have a heat conducting function, and in an application scenario, the heat conducting plate, the heat conducting pillar 116, the supporting plate 112 and the accommodating tube 113 all can be made of a heat conducting material, such as aluminum, aluminum alloy, stainless steel, or a polymer composite material with a heat conducting function. In addition, the cover 13 and the connecting plate 111 may be made of a material that is not easy to conduct heat, for example, the cover 13 may be made of acrylonitrile-butadiene-styrene (ABS), the connecting plate 111 may be made of plastic, Polyoxymethylene (POM), and the like, because the cover 13 covers the first opening 122 of the accommodating groove 121, and the connecting plate 111 and the related connecting structure cover the second opening 123 of the accommodating groove 121, the accommodating groove 121 forms a relatively closed space, thereby effectively reducing outward diffusion of air in the accommodating groove 121 and reducing outward conduction of heat.
It should be noted that, in the present embodiment, the heat-conducting column 116 can further conduct the heat conducted by the heat-conducting plate 115 to the supporting plate 112 through the connection with the heat-conducting plate 115, so as to directly heat the sample-accommodating member 500 placed on the supporting plate 112. Further, the heat conducting plate 115, the heat conducting post 116, the accommodating tube 113 and the supporting plate 112 in this embodiment may also be used to further conduct the heat generated by the heating element 114 to the air in the accommodating groove 121, heat the air in the accommodating groove 121, so as to heat the sample accommodating element 500 through the heated air, and the accommodating tube 113 and the supporting plate 112 may directly heat the air in the accommodating channel 1131, and each accommodating tube 113 is relatively independent, thereby further reducing the influence of the temperature in the accommodating tube 113 on the external environment, and reducing the fluctuation of the temperature. In this way, the arrangement of the heat conducting plate 115, the heat conducting columns 116 and the supporting plate 112 with heat conducting function enables the sample incubation device 100 to heat the sample container 500 by solid direct heating and air bath, thereby improving the efficiency of incubating the sample in the sample container 500.
In addition, since the accommodating groove 121 is relatively closed, the heated air in the accommodating groove is relatively less diffused outwards, and the incubation disc 11 can rotate in the accommodating groove 121 under the driving of the power mechanism 30, and the rotational motion of the incubation disc 11 promotes the air flowability in the accommodating groove 121 to be enhanced, thereby contributing to the improvement of the uniformity of the air temperature in the accommodating groove 121. Furthermore, the heating speed can be increased by the mode of heating the solid directly and the air bath simultaneously, and the temperature fluctuation is small.
It should be further noted that the heat conducting plate 115 and the supporting plate 112 can be made of sheet metal, and the accommodating tube 113 can be made of standard aluminum tube by cutting, so that the instrument can be conveniently processed and assembled, and the cost is low, thereby improving the overall economy of the instrument.
Further, in one embodiment, the heat conducting plate 115 may have a plurality of heat conducting holes 1151, and the plurality of heat conducting holes 1151 respectively have a one-to-one correspondence relationship with the plurality of positioning holes 1111 and the plurality of accommodating tubes 113. Each accommodating tube 113 is in clearance fit with the corresponding heat conduction hole 1151, and can penetrate through the heat conduction plate 115 through the corresponding heat conduction hole 1151 to be communicated with the corresponding positioning hole 1111, and the inner side wall of the heat conduction hole 1151 is abutted to the outer side wall of the corresponding accommodating tube 113.
In this embodiment, the accommodating tube 113 may also be made of a heat conductive material, so that the heat conducted by the heat conductive plate 115 can be received by the contact between the inner sidewall of the heat conductive hole 1151 and the outer sidewall of the accommodating tube 113, the air in the accommodating tube 113 can be heated, and the sample accommodating member 500 placed in the accommodating tube 113 can be heated by the heated air.
Further, with reference to fig. 4, in an embodiment, the connection plate 111 is provided with a first through hole 1113, one side of the rotation shaft 22 facing the connection plate 111 is provided with a second through hole 222 corresponding to the first through hole 1113, and the sample incubation device 100 further includes an assembly member 60, wherein the assembly member 60 penetrates the first through hole 1113 from one side of the connection plate 111 far away from the rotation shaft 22 and enters the second through hole 222, so that the connection plate 111 is detachably mounted on one side of the rotation shaft 22.
It should be noted that the number of the first assembly holes 1113, the second assembly holes 222 and the assembly members 60 is the same, and may be one or more, and have a one-to-one correspondence relationship. Specifically, the fitting 60 may be a detachable connector such as a screw.
In the present embodiment, since the connection plate 111 is provided on the side of the rotation shaft 22 away from the bottom plate 200, i.e., toward the mounting opening 400 of the sample analyzer, and the fitting 60 is provided so as to be able to pass through the first fitting hole 1113 and enter the second fitting hole 222 from the side of the connection plate 111 away from the rotation shaft 22, an operator can easily mount or dismount the fitting 60 through the mounting opening 400 when mounting or dismounting the connection plate 111, thereby improving maintainability of the apparatus.
In addition, in one embodiment, in this embodiment, the components of the incubation tray 11, such as the connection plate 111, the heating member 114, the heat conducting plate 115, the heat conducting post 116, the supporting plate 112, the accommodating tube 113, etc., can be directly or indirectly, detachably or non-detachably mounted together by screws and positioning pins, so as to form an integral structure, and the incubation tray 11 is mounted on the rotating shaft 22 by the connection between the connection plate 111 and the rotating shaft 22, so that when the incubation tray 11 needs to be disassembled, the whole incubation tray 11 can be taken down by directly disassembling the assembly part 60, which is convenient for the operator to operate.
Furthermore, the incubation tray 11 may further include a temperature sensor, a temperature protection switch, and other components, wherein the heating element 114, the temperature sensor, and the temperature protection switch are all accommodated in the accommodating groove 1112 of the connecting plate 111, and an opening of the accommodating groove 1112 is covered by the heat conducting plate 115 to form a closed space, so that the overall structure of the incubation tray 11 is more compact, and meanwhile, liquid is effectively prevented from being splashed onto electrical elements such as the heating element 114, and the safety performance and the service life of the incubation tray 11 can be improved.
Further, with continued reference to fig. 1 and fig. 2, in one embodiment, the sample incubation apparatus 100 further includes an optical coupler 70, and the optical coupler 70 may be used to detect the initial position of the incubation plate 11.
In this embodiment, the outer side wall of the housing 12 defines a mounting position of the optical coupler 70, and the optical coupler 70 is detachably mounted on the mounting position of the optical coupler 70. That is, in the present embodiment, the optical coupler is detachably mounted on the outer sidewall of the housing 12, so that an operator can conveniently enter from the mounting opening 400 to detach and mount the optical coupler.
Further, with continued reference to fig. 2, in one embodiment, the power mechanism 30 includes a mounting side 33 facing the mounting opening 400.
The sample incubation device 100 may further include a mounting bracket 80 and a mounting member 90, wherein the mounting bracket 80 is disposed on a side of the power mechanism 30 away from the mounting opening 400 and is mounted on the bottom plate 200, and further, the mounting member 90 may detachably mount the power mechanism 30 on the mounting bracket 80 through the mounting side 33.
In the present embodiment, since the mounting member 90 detachably mounts the power mechanism 30 to the mounting bracket 80 on the side of the power mechanism 30 facing the mounting opening 400, an operator can easily detach and mount the power mechanism 30 from the mounting opening 400 of the sample analyzer, thereby further improving the maintainability of the apparatus.
The above embodiments are merely examples and are not intended to limit the scope of the present disclosure, and all modifications, equivalents, and flow charts using the contents of the specification and drawings of the present disclosure or those directly or indirectly applied to other related technical fields are intended to be included in the scope of the present disclosure.
Claims (12)
1. The utility model provides a device is hatched to sample, is applied to sample analyzer, its characterized in that, sample analyzer includes a bottom plate to have an accommodation space and with the installing port of accommodation space intercommunication, the device is hatched to sample sets up in the accommodation space, and install on the bottom plate, the installing port is located one side that deviates from the bottom plate of device is hatched to sample, the device is hatched to sample includes:
the incubation mechanism is arranged on the bottom plate, is arranged at intervals with the bottom plate, is used for incubating samples, and comprises an incubation disc used for bearing the samples to be tested;
the power mechanism is arranged on the bottom plate and used for providing power;
the transmission mechanism is respectively connected with the incubation mechanism and the power mechanism and is used for receiving power provided by the power mechanism so as to drive the incubation disc to rotate;
the connecting part of the transmission mechanism and the power mechanism is arranged between the bottom plate and the incubation mechanism, and the distance from the transmission mechanism to the incubation disc is not more than the distance from the transmission mechanism to the bottom plate.
2. The sample incubation device of claim 1, wherein the transmission mechanism comprises:
one end of the rotating shaft is connected with the incubation disc;
the synchronous belt wheel is connected with the other end of the rotating shaft, which is far away from the incubation disc;
the power mechanism comprises:
a driving wheel;
and the transmission belt is respectively connected with the driving wheel and the synchronous belt wheel so as to drive the synchronous belt wheel to rotate along with the driving wheel, and then the incubation disc is driven to rotate through the rotating shaft.
3. The sample incubation device of claim 2, wherein the length of the rotating shaft is no greater than the axial distance of the synchronous pulley to the bottom plate.
4. The sample incubation device of claim 2, wherein the rotating shaft has an axially through mounting channel therein, the sample incubation device further comprising:
one end of the fixed shaft is fixed on the bottom plate, and the other end, far away from the bottom plate, of the fixed shaft is arranged in the installation channel;
the transmission mechanism further includes:
first swivel bearing, second swivel bearing, the interval set up in the installation passageway, and the inner circle all overlap and establish and install the periphery of fixed axle, the outer lane all with the inside wall butt of installation passageway, so that power unit's drive down, the rotation axis for the fixed axle rotates.
5. The sample incubation device of claim 2, wherein the incubation mechanism comprises:
the shell is provided with an accommodating groove, a first opening which is communicated with the accommodating groove and is positioned on one side of the shell, which is far away from the bottom plate, and a second opening which is positioned on one side of the shell, which is far towards the bottom plate;
the cover body is covered at the first opening;
the incubation disc is positioned in the accommodating groove and covers the second opening, and one end, far away from the synchronous belt pulley, of the rotating shaft is connected with the incubation disc at the second opening;
the sample incubation device further comprises a support shaft, one end of the support shaft is connected with the shell, and the other end of the support shaft is connected with the bottom plate, so that the shell is installed on the bottom plate.
6. The sample incubation device of claim 5, wherein the incubation tray comprises:
the connecting plate is connected with one end of the rotating shaft, which is far away from the synchronous belt pulley, and is provided with a plurality of positioning holes which are mutually spaced;
the supporting plate is arranged at an interval with the connecting plate and is positioned on one side of the connecting plate, which faces the bottom plate;
the holding pipes are connected between the connecting plate and the supporting plate and are arranged at intervals and respectively correspond to the positioning holes one by one, wherein each holding pipe is provided with a holding pipeline with two open ends, one end of each holding pipe is connected with the connecting plate, is arranged around the periphery of the corresponding positioning hole and is communicated with the corresponding positioning hole, and the other end of each holding pipe is abutted against the supporting plate, so that the sample holding piece can be held in a space defined by the positioning hole and the holding pipeline together and is placed on the supporting plate.
7. The sample incubation device of claim 6, wherein the support plate is made of a thermally conductive material, and a receiving groove is formed on a side of the connection plate facing the bottom plate, and the incubation tray further comprises:
the heating element is arranged in the accommodating groove and used for generating heat;
the heat conducting plate is covered outside the accommodating groove to seal the accommodating groove and is connected with the heating element to conduct heat generated by the heating element;
the heat conduction column is connected and arranged between the heat conduction plate and the support plate and is used for further conducting heat conducted by the heat conduction plate to the support plate so as to heat the sample accommodating part placed on the support plate;
the heat conducting plate is also used for conducting heat generated by the heating element to the air in the accommodating groove, and heating the air in the accommodating groove so as to heat the sample accommodating element through the heated air.
8. The sample incubation device according to claim 7, wherein the heat-conducting plate defines a plurality of heat-conducting holes, the plurality of heat-conducting holes respectively correspond to the plurality of positioning holes and the plurality of accommodating tubes, each accommodating tube communicates with the corresponding positioning hole through the heat-conducting plate via the corresponding heat-conducting hole, and an inner sidewall of the heat-conducting hole abuts against an outer sidewall of the corresponding accommodating tube.
9. The sample incubation device according to claim 6, wherein the connection plate is provided with a first through hole, the rotation shaft is provided with a second through hole corresponding to the first through hole on one side of the connection plate, and the sample incubation device further comprises an assembly member which penetrates the first through hole from one side of the connection plate close to the mounting opening and enters the second through hole, so that the connection plate is detachably mounted on one side of the rotation shaft.
10. The sample incubation device of claim 5, wherein the housing defines an outer sidewall with a light coupling mounting location;
the sample incubation device further comprises an optical coupler, and the optical coupler is detachably mounted on the optical coupler mounting position.
11. The sample incubation device of claim 1, wherein the actuating mechanism comprises a mounting side facing the mounting opening;
the sample incubation device further comprises:
the mounting bracket is arranged on one side of the power mechanism, which is far away from the mounting opening, and is mounted on the bottom plate;
the mounting piece detachably mounts the power mechanism on the mounting bracket through the mounting side.
12. A sample analyzer, comprising:
a base plate;
a sample incubation device mounted on the base plate, wherein the sample incubation device is as claimed in any one of claims 1 to 11.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010753020.1A CN114062067B (en) | 2020-07-30 | 2020-07-30 | Sample incubation device and sample analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010753020.1A CN114062067B (en) | 2020-07-30 | 2020-07-30 | Sample incubation device and sample analyzer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114062067A true CN114062067A (en) | 2022-02-18 |
| CN114062067B CN114062067B (en) | 2024-04-19 |
Family
ID=80226665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010753020.1A Active CN114062067B (en) | 2020-07-30 | 2020-07-30 | Sample incubation device and sample analyzer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114062067B (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010019826A1 (en) * | 1998-05-01 | 2001-09-06 | Gen-Probe Incorporated | Automated diagnostic analyzer and method |
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
| CN207457256U (en) * | 2017-09-30 | 2018-06-05 | 深圳迈瑞生物医疗电子股份有限公司 | Automatic clinical chemistry analyzer |
| CN108226463A (en) * | 2018-01-19 | 2018-06-29 | 深圳市亚辉龙生物科技股份有限公司 | Blending incubation device and method |
| CN207798861U (en) * | 2017-08-16 | 2018-08-31 | 北京普利生仪器有限公司 | Sample analysis apparatus and its sample incubation device |
| CN209560376U (en) * | 2018-11-28 | 2019-10-29 | 深圳市帝迈生物技术有限公司 | Incubate device and the sample analyser comprising it |
| CN110441539A (en) * | 2019-08-21 | 2019-11-12 | 东软威特曼生物科技（沈阳）有限公司 | Reaction cup holder and automatic clinical chemistry analyzer for solid directly-heated type or air bath reaction tray |
| CN111381057A (en) * | 2018-12-29 | 2020-07-07 | 深圳市帝迈生物技术有限公司 | Sample analyzer and control method thereof |
-
2020
- 2020-07-30 CN CN202010753020.1A patent/CN114062067B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010019826A1 (en) * | 1998-05-01 | 2001-09-06 | Gen-Probe Incorporated | Automated diagnostic analyzer and method |
| CN207798861U (en) * | 2017-08-16 | 2018-08-31 | 北京普利生仪器有限公司 | Sample analysis apparatus and its sample incubation device |
| CN207457256U (en) * | 2017-09-30 | 2018-06-05 | 深圳迈瑞生物医疗电子股份有限公司 | Automatic clinical chemistry analyzer |
| CN108061809A (en) * | 2017-11-27 | 2018-05-22 | 桂林优利特医疗电子有限公司 | Biochemical instruments react cup holding rack and reaction tray movement accuracy-control system |
| CN108226463A (en) * | 2018-01-19 | 2018-06-29 | 深圳市亚辉龙生物科技股份有限公司 | Blending incubation device and method |
| CN209560376U (en) * | 2018-11-28 | 2019-10-29 | 深圳市帝迈生物技术有限公司 | Incubate device and the sample analyser comprising it |
| CN111381057A (en) * | 2018-12-29 | 2020-07-07 | 深圳市帝迈生物技术有限公司 | Sample analyzer and control method thereof |
| CN110441539A (en) * | 2019-08-21 | 2019-11-12 | 东软威特曼生物科技（沈阳）有限公司 | Reaction cup holder and automatic clinical chemistry analyzer for solid directly-heated type or air bath reaction tray |
Non-Patent Citations (1)
| Title |
|---|
| 徐春英;李玉中;郝卫平;李巧珍;董一威;房福力;郭智成;: "反硝化细菌法结合痕量气体分析仪/同位素比质谱仪分析水体硝酸盐氮同位素组成", 分析化学, no. 09, 30 September 2012 (2012-09-30), pages 1360 - 1365 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114062067B (en) | 2024-04-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4569030B2 (en) | Fluorescence detection method and apparatus capable of measurement under external light | |
| US5229074A (en) | Automatic multiple-sample multiple-reagent chemical analyzer | |
| CN114062067A (en) | Sample incubation device and sample analyzer | |
| CN114062102A (en) | Sample incubation device and sample analyzer | |
| CN113324985B (en) | Centrifugal micro-fluidic detection device and centrifugal micro-fluidic detection system | |
| CN215178997U (en) | Sample incubation device and sample analyzer | |
| CN114878668B (en) | Full-automatic dry three-electrode electrochemiluminescence analyzer and application thereof in electrochemiluminescence detection | |
| CN110672595A (en) | Water quality monitor | |
| CN111999460A (en) | Rapid quantitative analysis mechanism of trace silicate analyzer and use method thereof | |
| CN111812340B (en) | Temperature raising disc mechanism of full-automatic urine specific protein analyzer | |
| CN108444799A (en) | A kind of blending incubation device | |
| CN111394220B (en) | Nucleic acid extraction device | |
| CN220564625U (en) | Biological agent activity detection device | |
| CN113019213A (en) | Water bath test or inspection device | |
| CN219348885U (en) | Reaction disc system and full-automatic inspection instrument | |
| CN208591853U (en) | A kind of constant-temperature incubation device | |
| CN216926563U (en) | Constant temperature reaction device | |
| CN100365418C (en) | Flowing injection unit for immobilized enzyme biosensor analyzer | |
| CN211057114U (en) | Fluorescent quantitative PCR instrument | |
| CN213824849U (en) | Reaction cup mixing device | |
| CN216718414U (en) | Multichannel fast switching device suitable for water quality automatic detector | |
| CN214585508U (en) | Full-automatic biochemical analyzer sample injector | |
| CN115901396A (en) | Intelligent full-automatic blood sample preprocessing instrument | |
| CN219328803U (en) | Partition sample tray and full-automatic inspection instrument | |
| CN215540816U (en) | Reaction cup for electrolyte analyzer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant |