CN115901396A - Intelligent full-automatic blood sample preprocessing instrument - Google Patents
Intelligent full-automatic blood sample preprocessing instrument Download PDFInfo
- Publication number
- CN115901396A CN115901396A CN202211669345.7A CN202211669345A CN115901396A CN 115901396 A CN115901396 A CN 115901396A CN 202211669345 A CN202211669345 A CN 202211669345A CN 115901396 A CN115901396 A CN 115901396A
- Authority
- CN
- China
- Prior art keywords
- control module
- temperature
- module
- shell
- sample tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Abstract
The invention belongs to the field of medical devices, and discloses an intelligent full-automatic blood sample pretreatment instrument, which comprises a shell; a rotating module, a sample tube and a control module are arranged in the shell; the sample tube is connected with the rotating module, and two accommodating spaces are arranged in the sample tube; a temperature control module is arranged on one side of the shell, and the temperature control module and the rotating module are both connected with the control module; the temperature control module is used for monitoring the real-time temperature in the shell and sending the real-time temperature to the control module; the control module is used for acquiring a rotation control signal and controlling the rotation module to rotate the sample tube according to the rotation control signal; and the temperature control module is also used for acquiring a temperature control signal and controlling the internal temperature of the shell by controlling the temperature control module according to the temperature control signal and the real-time temperature. The method can integrate the operations of reagent addition, impurity cell lysis, centrifugal separation, mixing, antibody combination, dyeing, constant-temperature incubation and the like, has low professional requirements on operators, is low in cost, has stable and adjustable internal temperature, and can adapt to different detection environments.
Description
Technical Field
The invention belongs to the field of medical devices, and relates to an intelligent full-automatic blood sample pretreatment instrument.
Background
Blood detection has important significance and value in disease diagnosis. By detecting components or cells in blood, an important basis can be provided for disease diagnosis or drug treatment effect. Taking aids detection as an example, there are tens of thousands of new aids patients each year at present, and there is a further increasing trend. In the detection of AIDS, the cell such as CD4 in blood can be detected, so as to provide reference for the diagnosis of AIDS and the curative effect of anti-AIDS drugs. In order to accurately detect components or cells in blood, a blood sample needs to be pretreated, and the pretreatment generally comprises the processes of adding reagents, lysing impurity cells, centrifuging, mixing, dyeing, and incubating at constant temperature. The purpose of pre-treating blood samples mainly includes: 1) Separating the component to be measured from the complex sample to prepare a solution form convenient for measurement; 2) Removing matrix material that interferes with the analytical determination; 3) When the concentration of the component to be detected is low, the concentration of the component to be detected is improved through concentration and enrichment, such as centrifugation and other operations; 4) The substance to be detected is quantitatively converted into another substance which is easy to detect by means of derivatization treatment of a sample and the like.
At present, the blood sample pretreatment operation of the majority of medical health departments and laboratories still adopts an artificial mode. The sample pretreatment process has the disadvantages of complicated steps, complex operation, high professional requirement, high experimental environment requirement, time and labor consumption, and the risk of influencing the subsequent detection accuracy due to human misoperation exists. Therefore, the operation of blood sample pretreatment is integrated, intelligentized and automated, the traditional manual operation is replaced by the high efficiency and the accuracy of the machine work, and the method has huge application potential and market prospect. At present, few blood sample pretreatment instruments are reported, most of the existing blood sample pretreatment instruments have single functions, can only realize single-type detection or can only realize a single process in pretreatment, and cannot meet the diversified requirements of blood sample pretreatment.
Disclosure of Invention
The invention aims to overcome the defects that the existing blood sample pretreatment instrument in the prior art has single function and cannot meet the diversified requirements of blood sample pretreatment, and provides an intelligent full-automatic blood sample pretreatment instrument.
In order to achieve the purpose, the invention adopts the following technical scheme to realize the purpose:
an intelligent full-automatic blood sample pretreatment instrument comprises a shell; a rotating module, a sample tube and a control module are arranged in the shell; the sample tube is connected with the rotating module, and two accommodating spaces are arranged in the sample tube; a temperature control module is arranged on one side of the shell, and the temperature control module and the rotating module are both connected with the control module; the temperature control module is used for monitoring the real-time temperature in the shell and sending the real-time temperature to the control module; the control module is used for acquiring a rotation control signal and controlling the rotation module to rotate the sample tube according to the rotation control signal; and the temperature control module is also used for acquiring a temperature control signal and controlling the internal temperature of the shell by controlling the temperature control module according to the temperature control signal and the real-time temperature.
Optionally, the rotating module includes a motor, a motor driving board, a transmission assembly and a rotating shaft; the control end of the motor is connected with the control module through a motor drive plate, and the output shaft of the motor is connected with the rotating shaft through a transmission assembly; the one end that transmission assembly was kept away from to the axis of rotation sets up the sample cell support that can dismantle, sets up a plurality of mounting holes that are used for the holding sample cell on the sample cell support.
Optionally, a spring buckle sensor is arranged in the mounting hole, a mounting groove matched with the spring buckle sensor is formed in the outer wall of the sample tube, and the sample tube and the spring buckle sensor are fixed in the mounting hole through the mounting groove; the spring buckle sensor is used for detecting whether a sample tube exists in the mounting hole or not, obtaining sample tube detection information and sending the sample tube detection information to the control module.
Optionally, a partition plate is arranged in the housing, and divides the housing into a control cavity and an operation cavity; the motor and the transmission assembly are positioned in the control cavity, the sample tube bracket is positioned in the operation cavity, and the rotating shaft penetrates through the isolation plate; the operation cavity of the shell is provided with a side plate capable of being opened and closed.
Optionally, the sample tube comprises a cover body and a tube body which are connected with each other; a first containing space is arranged in the cover body, and a second containing space is arranged in the tube body.
Optionally, a dried reagent or a soluble reagent capsule is arranged in the first accommodating space; when the reagent drying and dissolving device is used, the dried reagent or the reagent dissolving capsule can be dissolved by liquid contained in the second containing space.
Optionally, the temperature control module includes a heating component, a refrigerating component and a temperature sensor; the heating assembly and the refrigerating assembly are both connected with the control module and are both arranged on one side of the shell; the heating assembly is used for increasing the temperature inside the shell, and the refrigerating assembly is used for reducing the temperature inside the shell; the temperature sensor is connected with the control module, and one end of the temperature sensor is located inside the shell and used for monitoring the real-time temperature inside the shell and sending the real-time temperature to the control module.
Optionally, the heating assembly and the refrigerating assembly adopt the same semiconductor refrigerating sheet and circuit switching module; the two working surfaces of the semiconductor refrigerating sheet are oppositely arranged, and one working surface is positioned in the shell; the two working surfaces are provided with radiating fins; the control end of the semiconductor refrigeration piece is connected with the circuit switching module, the circuit switching module is connected with the control module, and the control module is used for controlling the direction of the current inside the semiconductor refrigeration piece through the circuit switching module.
Optionally, a heat dissipation fan is arranged on one side of the heat dissipation sheet, which is far away from the working surface, and heat conduction silicone grease is arranged between the heat dissipation sheet and the working surface.
Optionally, the control module includes a control unit and a human-computer interaction unit connected to each other; the control unit is connected with both the temperature control module and the rotating module, and the human-computer interaction unit is used for acquiring a rotation control signal and a temperature control signal and sending the rotation control signal and the temperature control signal to the control unit; the display control unit is also used for displaying real-time temperature and rotation control signals and temperature control signals sent by the control unit; the control unit is used for controlling the rotating module to rotate the sample tube according to the rotating control signal; and the temperature control module is also used for controlling the internal temperature of the shell according to the temperature control signal and the real-time temperature.
Compared with the prior art, the invention has the following beneficial effects:
the intelligent full-automatic blood sample pretreatment instrument has the characteristic of modular design, and intelligently senses and regulates the internal temperature of the shell by arranging the temperature control module; by arranging the sample tube and arranging the two accommodating spaces in the sample tube, different reagents can be accommodated as required, different components and cells in blood can be detected, and the device has better applicability and can meet different detection requirements; the rotation of the sample tube is realized by arranging the rotation module, and the mixing, dyeing, cracking, centrifugation and the like of substances in the sample tube are realized. This intelligent full-automatic blood specimen preprocessing instrument has automatic and integrated characteristics, can integrate and realize operations such as reagent addition, impurity cell schizolysis, centrifugal separation, mixture, antibody combination, dyeing, constant temperature incubation, and the professional requirement to operating personnel is low, and is small, with low costs, and inside temperature is stable adjustable, can adapt to different detection environment.
Drawings
Fig. 1 is a schematic structural view of an intelligent fully-automatic blood sample pretreatment instrument according to an embodiment of the present invention.
Fig. 2 is a schematic view of a planar structure of a single mounting hole of a sample tube holder according to an embodiment of the present invention.
Fig. 3 is a schematic diagram of a cover structure of a sample tube according to an embodiment of the present invention.
Fig. 4 is a schematic structural diagram of a tube body of a sample tube according to an embodiment of the present invention.
Wherein: 1-a shell; 2-a control chamber; 3-an operation cavity; 4-a separation plate; 5-side plates; 6, a motor; 7-a motor drive board; 8-a transmission assembly; 9-a control unit; 10-a temperature control module; 11-a rotating shaft; 12-sample tube holder; 13-a human-computer interaction unit; 14-spring snap sensor; 15-a cover body; 16-a tube body.
Detailed Description
In order to make the technical solutions of the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It should be noted that the terms "first," "second," and the like in the description and claims of the present invention and in the drawings described above are used for distinguishing between similar elements and not necessarily for describing a particular sequential or chronological order. It is to be understood that the data so used is interchangeable under appropriate circumstances such that the embodiments of the invention described herein are capable of operation in sequences other than those illustrated or described herein. Furthermore, the terms "comprises," "comprising," and "having," and any variations thereof, are intended to cover a non-exclusive inclusion, such that a process, method, system, article, or apparatus that comprises a list of steps or elements is not necessarily limited to those steps or elements expressly listed, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus.
The invention is described in further detail below with reference to the accompanying drawings:
referring to fig. 1 to 4, in an embodiment of the present invention, an intelligent fully automatic blood sample pretreatment apparatus is provided, which includes a housing 1; a rotating module, a sample tube and a control module are arranged in the shell 1; the sample tube is connected with the rotating module, and two accommodating spaces are arranged in the sample tube; a temperature control module 10 is arranged on one side of the shell 1, and the temperature control module 10 and the rotating module are both connected with a control module; the temperature control module 10 is used for monitoring the real-time temperature inside the shell 1 and sending the real-time temperature to the control module; the control module is used for acquiring a rotation control signal and controlling the rotation module to rotate the sample tube according to the rotation control signal; and is also used for acquiring a temperature control signal and controlling the internal temperature of the shell 1 by controlling the temperature control module 10 according to the temperature control signal and the real-time temperature.
The temperature control module 10 is used for stably controlling the internal environment temperature of the instrument and providing required temperature conditions for operations such as cell activity maintaining and incubation maintaining; the sample tube is used for providing places for fully mixing the blood sample with other reagents, centrifuging the blood sample and reacting, and simultaneously providing reagents required by the reaction; the control module is used for realizing parameter setting and detection control; the housing 1 serves to isolate the interior space from the exterior environment and to provide the desired spatial environment for the pretreatment of the blood sample.
In summary, the intelligent full-automatic blood sample pretreatment instrument has the characteristic of modular design, and intelligently senses and regulates the internal temperature of the shell by arranging the temperature control module; by arranging the sample tube and arranging the two accommodating spaces in the sample tube, different reagents can be accommodated as required, different components and cells in blood can be detected, and the device has better applicability and can meet different detection requirements; realize the rotation of sample cell through setting up the rotation module, realize the mixing of the intraductal object of sample, dyeing, schizolysis and centrifugation etc. have characteristics automatic and integration, can integrate and realize that reagent adds, impurity cell schizolysis, centrifugation, mix, antibody combine, operation such as dyeing, constant temperature incubation, low to operating personnel's professional requirement, small, with low costs, and inside temperature is stable adjustable, can adapt to different detection ring border.
In one possible embodiment, the rotating module comprises a motor 6, a motor driving plate 7, a transmission assembly 8 and a rotating shaft 11; the control end of the motor 6 is connected with the control module through a motor drive plate 7, and the output shaft of the motor 6 is connected with a rotating shaft 11 through a transmission assembly 8; one end of the rotating shaft 11, which is far away from the transmission assembly 8, is provided with a detachable sample tube support 12, and the sample tube support 12 is provided with a plurality of mounting holes for accommodating sample tubes.
Specifically, the control module is connected with the motor 6 and can control parameters such as the rotating direction, the rotating speed, the rotating time and the like of the motor 6; the control module controls the motor drive board 7 to output a specific digital signal, so that the purpose of controlling the rotation of the motor 6 is achieved. The motor 6 is connected with the transmission assembly 8, the transmission assembly 8 is connected with the rotating shaft 11, the transmission assembly 8 transmits the rotation of the motor 6 to the rotating shaft 11, the sample tube support 12 is fixed on the rotating shaft 11, and the sample tube support 12 rotates along with the rotating shaft 11.
Wherein, the transmission assembly 8 can be realized by a transmission gear. Optionally, a bearing may be further provided, the bearing is fixed to the housing, and the bearing is connected to the rotating shaft 11 to support the rotating shaft 11.
In a possible embodiment, a partition plate 4 is arranged in the housing 1, dividing the housing 1 into a control chamber 2 and an operation chamber 3; the motor 6 and the transmission component 8 are positioned in the control cavity 2, the sample tube bracket 12 is positioned in the operation cavity 3, and the rotating shaft 11 transversely penetrates through the isolation plate 4; the operating chamber 3 of the housing 1 is provided with a side plate 5 that can be opened and closed. Optionally, the housing 1 is further provided with a mounting base and a positioning member for each component, so as to facilitate the processing of the whole device.
Specifically, through curb plate 5 that can open and shut, can be used to observe interior equipment behavior and provide the light-resistant environment for blood sample processing process.
Optionally, the motor driving board 7 is located right below the motor 6, and the motor 6 is located at the lower right of the control cavity 2 and close to the housing 1; the rotating shaft 11 is positioned in the center of the operation cavity 3, and a sample tube bracket 12 is fixed on the rotating shaft; the sample tube bracket 12 is a detachable component, so that a plurality of sample tubes can be inserted outside the device after being detached, and the sample tube bracket and the rotating shaft 11 form a combined body to rotate synchronously after being installed.
In a possible implementation manner, a spring buckle sensor 14 is arranged in the mounting hole, a mounting groove matched with the spring buckle sensor 14 is formed in the outer wall of the sample tube, and the sample tube and the spring buckle sensor 14 are fixed in the mounting hole through the mounting groove; the spring buckle sensor 14 is used for detecting whether a sample tube exists in the mounting hole or not, obtaining sample tube detection information and sending the sample tube detection information to the control module.
Specifically, the spring snap sensor 14, while serving as a spring snap, also serves as a switch, which is connected to the control module for detecting whether a sample tube is present in the corresponding mounting hole of the sample tube holder 12. When no sample tube is in the mounting hole, the spring buckle sensor 14 is in an extension state, and the switch is in a closing state at the moment; when the sample tube is inserted into the mounting hole, the spring snap sensor 14 is in a compressed state, and the switch is in an open state at the moment; the control module obtains the signal, records parameters such as the position serial number of the mounting hole, the time for inserting the sample tube into the mounting hole and the like, and can display the parameters on a display screen of the control module.
In a possible embodiment, the sample tube comprises a cover 15 and a tube 16 connected to each other; a first accommodating space is formed in the cover body 15, and a second accommodating space is formed in the pipe body 16.
Specifically, before use, the cover 15 and the tube 16 are two independent units, and the inner spaces of the two units are respectively closed. The space of the cover 15 facing the pipe 16 is not communicated with the space inside the pipe 16. The cover body 15 and the tube body 16 can be plugged by rubber plugs to form respective closed spaces. When the sealing device is used, the cover body 15 and the pipe body 16 are in sealing fit through interference fit or a threaded structure, so that the space of one side, facing the pipe body 16, of the cover body 15 is communicated with the inner space of the pipe body.
Optionally, the cover 15 may be used to store dried reagent or soluble reagent capsule on the side facing the tube 16, and the soluble reagent capsule is dissolved when contacting with the corresponding liquid, so as to release the quantitative reagent wrapped inside the soluble reagent capsule. Quantitative reagents are preset in the tube body 16, and a fixing clamping groove is designed on the outer wall surface of the tube body 16 and is used for being matched with the spring buckle sensor 14 on the sample tube support.
In one possible embodiment, the temperature control module 10 comprises a heating assembly, a cooling assembly and a temperature sensor; the heating assembly and the refrigerating assembly are both connected with the control module and are both arranged on one side of the shell 1; the heating assembly is used for increasing the internal temperature of the shell 1, and the refrigerating assembly is used for reducing the internal temperature of the shell 1; the temperature sensor is connected with the control module, and one end of the temperature sensor is positioned inside the shell 1 and used for monitoring the real-time temperature inside the shell 1 and sending the real-time temperature to the control module.
Optionally, the heating assembly and the refrigerating assembly adopt the same semiconductor refrigerating sheet and circuit switching module; two working surfaces of the semiconductor refrigerating sheet are oppositely arranged, and one working surface is positioned in the shell 1; the two working surfaces are provided with radiating fins; the control end of the semiconductor refrigeration piece is connected with the circuit switching module, the circuit switching module is connected with the control module, and the control module is used for controlling the direction of the current inside the semiconductor refrigeration piece through the circuit switching module. In order to enhance the heat exchange effect, a heat radiation fan may be disposed on one side of the heat radiation fin away from the working surface, and a heat conductive silicone grease may be disposed between the heat radiation fin and the working surface.
Specifically, the heat or cold generated by the semiconductor refrigerating sheet facing the side of the operation chamber 3 is transferred to the heat radiating sheet through the heat conducting silicone grease, and then the air convection is strengthened through the heat radiating fan, so that the heat or cold enters the operation chamber 3 to maintain the constant temperature in the operation chamber 3. The semiconductor refrigerating sheet correspondingly generates cold or heat on the surface back to the operation cavity 3, the cold or heat is transmitted to the radiating sheet through the heat-conducting silicone grease, and then the air convection is enhanced through the radiating fan, so that the cold or heat is transmitted into the external environment of the instrument, and the normal work of the semiconductor refrigerating sheet is ensured.
The semiconductor refrigerating sheet is based on the Peltier principle, and the current direction in the semiconductor refrigerating sheet is controlled through the circuit switching module, so that the heating or refrigerating function is achieved. Optionally, the circuit switching module is composed of a relay and an external power supply, and is controlled by the control module.
In a possible embodiment, the control module comprises a control unit 9 and a human-computer interaction unit 13 connected to each other; the control unit 9 is connected with the temperature control module 10 and the rotating module, and the human-computer interaction unit 13 is used for acquiring a rotation control signal and a temperature control signal and sending the rotation control signal and the temperature control signal to the control unit 9; and is also used for displaying the real-time temperature and the rotation control signal and the temperature control signal sent by the control unit 9; the control unit 9 is used for controlling the rotating module to rotate the sample tube according to the rotating control signal; and is also used for controlling the internal temperature of the shell 1 by controlling the temperature control module 10 according to the temperature control signal and the real-time temperature.
Specifically, a user can input a rotation control signal and a temperature control signal through the man-machine interaction unit 13, such as setting parameters of temperature, time, execution programs and the like; and displaying the real-time temperature sent by the control unit 9 and information such as the set temperature, the processing time, the operating step serial number and the like contained in the rotation control signal and the temperature control signal on a display screen. The control unit 9 controls the overall process of the apparatus.
Optionally, the control unit 9 is a single chip microcomputer and is located on one side of the motor drive plate 7 below the control cavity 2.
In one possible embodiment, the blood sample pretreatment before the detection of CD4 cells is taken as an example to illustrate the intelligent fully automatic blood sample pretreatment apparatus of the present invention.
In this embodiment, a blood sample is added into a sample tube, a predetermined amount of ACEA hemolysin is preset in a tube body 16 of the sample tube, and a predetermined amount of dried antibody capable of binding to CD4 cells is fixed to a side of the tube body 16 facing a cover 15 of the sample tube. The special sample tube is inserted into the sample tube support 12, the fixing clamping groove on the outer wall of the tube body 16 is matched with the spring buckle sensor 14 on the sample tube support, the spring buckle sensor 14 is fixed and detects that the sample tube exists in the mounting hole, and the detection information is transmitted to the control unit 9 and the human-computer interaction interface 13 to be displayed. The user sets parameters such as temperature, time and execution program through the man-machine interaction interface 13; the corresponding parameters are detected by internal sensors and displayed on the human-computer interaction interface 13 by the control unit 9. The temperature control module 10 realizes real-time monitoring and dynamic control of the temperature inside the casing 1, and maintains a suitable temperature for cell incubation.
The motor 6 in the rotating module receives the instruction of the control unit 9, rotates according to certain program steps, further drives the rotating shaft 11, the sample tube bracket 12 and the sample tube to perform mixed motion, and then stands in a dark place for incubation for a certain time to realize the lysis of the red blood cells of the blood sample. Subsequently, under the drive of the motor 6, the sample tube support 12 drives the sample tube to turn over and move in a circumferential reciprocating manner, and the sample tube is kept standing for incubation for a certain time in a dark place, so that the dissolution of the dried antibody and the specific combination with the CD4 cells are realized, and finally the staining of the cells is realized. After the flow operation is completed, the sample tube is placed right under the action of the motor 6, the completion of sample pretreatment is displayed through the human-computer interaction interface 13, and the user is informed.
In conclusion, the intelligent full-automatic blood sample pretreatment instrument has the characteristic of intelligence, and intelligent detection and control of the whole operation are realized through the intelligent human-computer interaction interface 13 and the control unit 9. The temperature inside the instrument is intelligently sensed and regulated through the temperature control module 10. Through the spring buckle sensor 14 on the sample tube bracket 12, the state of the sample tube can be intelligently identified and detected. The invention has the characteristic of modular design, can detect different components and cells in blood by changing the preset reagent, the dried reagent or the soluble reagent capsule in the sample tube, has better applicability and can meet different detection requirements. The invention is provided with the sample tube bracket with a plurality of mounting holes, can be used for preprocessing a plurality of blood samples at the same time, and has high efficiency. Therefore, the novel efficient intelligent full-automatic blood sample pretreatment instrument provided by the invention has wide popularization prospect and application value in the vast medical institutions, especially the basic medical institutions.
The above-mentioned contents are only for illustrating the technical idea of the present invention, and the protection scope of the present invention is not limited thereby, and any modification made on the basis of the technical idea of the present invention falls within the protection scope of the claims of the present invention.
Claims (10)
1. An intelligent full-automatic blood sample pretreatment instrument is characterized by comprising a shell (1);
a rotating module, a sample tube and a control module are arranged in the shell (1); the sample tube is connected with the rotating module, and two accommodating spaces are arranged in the sample tube; a temperature control module (10) is arranged on one side of the shell (1), and the temperature control module (10) and the rotating module are both connected with the control module;
the temperature control module (10) is used for monitoring the real-time temperature in the shell (1) and sending the real-time temperature to the control module;
the control module is used for acquiring a rotation control signal and controlling the rotation module to rotate the sample tube according to the rotation control signal; and the temperature control module is also used for acquiring a temperature control signal and controlling the internal temperature of the shell (1) through the control temperature control module (10) according to the temperature control signal and the real-time temperature.
2. The intelligent fully-automatic blood sample pretreatment instrument according to claim 1, wherein the rotation module comprises a motor (6), a motor driving board (7), a transmission assembly (8) and a rotation shaft (11);
the control end of the motor (6) is connected with the control module through a motor drive plate (7), and the output shaft of the motor (6) is connected with a rotating shaft (11) through a transmission assembly (8); one end of the rotating shaft (11) far away from the transmission assembly (8) is provided with a detachable sample tube bracket (12), and the sample tube bracket (12) is provided with a plurality of mounting holes for accommodating sample tubes.
3. The intelligent full-automatic blood sample pretreatment instrument according to claim 2, wherein a spring snap sensor (14) is arranged in the mounting hole, a mounting groove matched with the spring snap sensor (14) is formed in the outer wall of the sample tube, and the sample tube is fixed in the mounting hole through the mounting groove and the spring snap sensor (14); the spring buckle sensor (14) is used for detecting whether a sample tube exists in the mounting hole or not, obtaining sample tube detection information and sending the sample tube detection information to the control module.
4. The intelligent fully-automatic blood sample pretreatment instrument according to claim 2, characterized in that a separation plate (4) is arranged in the housing (1) to divide the housing (1) into a control chamber (2) and an operation chamber (3);
the motor (6) and the transmission assembly (8) are positioned in the control cavity (2), the sample tube bracket (12) is positioned in the operation cavity (3), and the rotating shaft (11) transversely penetrates through the isolation plate (4); the operation cavity (3) of the shell (1) is provided with a side plate (5) which can be opened and closed.
5. The intelligent fully-automatic blood sample pretreatment instrument according to claim 1, wherein said sample tube comprises a cover (15) and a tube body (16) connected to each other;
a first accommodating space is formed in the cover body (15), and a second accommodating space is formed in the pipe body (16).
6. The intelligent fully-automatic blood sample pretreatment instrument according to claim 5, wherein a dried reagent or a dissolvable reagent capsule is disposed in the first accommodation space; when the reagent drying and dissolving device is used, the dried reagent or the reagent dissolving capsule can be dissolved by liquid contained in the second containing space.
7. The intelligent fully-automatic blood sample pretreatment instrument according to claim 1, wherein said temperature control module (10) comprises a heating component, a cooling component and a temperature sensor;
the heating assembly and the refrigerating assembly are both connected with the control module and are both arranged on one side of the shell (1); the heating assembly is used for increasing the internal temperature of the shell (1), and the refrigerating assembly is used for reducing the internal temperature of the shell (1);
the temperature sensor is connected with the control module, one end of the temperature sensor is located inside the shell (1) and used for monitoring the real-time temperature inside the shell (1) and sending the real-time temperature to the control module.
8. The intelligent full-automatic blood sample pretreatment instrument according to claim 7, wherein the heating assembly and the cooling assembly employ the same semiconductor cooling plate and circuit switching module;
the two working surfaces of the semiconductor refrigerating sheet are oppositely arranged, and one working surface is positioned in the shell (1); the two working surfaces are provided with radiating fins;
the control end of the semiconductor refrigeration piece is connected with the circuit switching module, the circuit switching module is connected with the control module, and the control module is used for controlling the direction of the current inside the semiconductor refrigeration piece through the circuit switching module.
9. The intelligent fully-automatic blood sample pretreatment instrument according to claim 8, wherein a heat dissipation fan is disposed on a side of the heat dissipation plate away from the working surface, and a heat conductive silicone grease is disposed between the heat dissipation plate and the working surface.
10. The intelligent fully automatic blood sample pretreatment instrument according to claim 1, characterized in that said control module comprises a control unit (9) and a human-machine interaction unit (13) connected to each other;
the control unit (9) is connected with the temperature control module (10) and the rotating module,
the man-machine interaction unit (13) is used for acquiring a rotation control signal and a temperature control signal and sending the rotation control signal and the temperature control signal to the control unit (9); the temperature control device is also used for displaying real-time temperature, a rotation control signal and a temperature control signal sent by the control unit (9);
the control unit (9) is used for controlling the rotating module to rotate the sample tube according to the rotating control signal; and the temperature control module is also used for controlling the internal temperature of the shell (1) by controlling the temperature control module (10) according to the temperature control signal and the real-time temperature.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211669345.7A CN115901396A (en) | 2022-12-24 | 2022-12-24 | Intelligent full-automatic blood sample preprocessing instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211669345.7A CN115901396A (en) | 2022-12-24 | 2022-12-24 | Intelligent full-automatic blood sample preprocessing instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115901396A true CN115901396A (en) | 2023-04-04 |
Family
ID=86472768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211669345.7A Pending CN115901396A (en) | 2022-12-24 | 2022-12-24 | Intelligent full-automatic blood sample preprocessing instrument |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN115901396A (en) |
-
2022
- 2022-12-24 CN CN202211669345.7A patent/CN115901396A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US9856517B2 (en) | Instrument for cassette for sample preparation | |
| EP3184158B1 (en) | Blood collector with capillary structure | |
| WO2007105198A2 (en) | Automated sampling and analysis using a pesonal sampler device | |
| CN106918715B (en) | A kind of chemiluminescence diagnostic device and its system | |
| US11360107B1 (en) | Systems and methods for sample handling | |
| US20200150138A1 (en) | Laboratory instrument and insertable network instrument | |
| CN115901396A (en) | Intelligent full-automatic blood sample preprocessing instrument | |
| EP3888795A1 (en) | Centrifuge and specimen preparation device | |
| EP4127647A1 (en) | Sex toy adapted to collect body fluid and/or cells for diagnostic testing | |
| CN112284865A (en) | Slide pretreatment system | |
| CN109030139B (en) | Luminous immunity quality control re-melting device | |
| CN204824895U (en) | A portable environmental chamber for test paper | |
| CN208308862U (en) | A kind of TCF7L2 rs7903146 gene parting detecting reagent | |
| CN115197834A (en) | Nucleic acid detection equipment with separation air channel design and nucleic acid detection method | |
| US20200191813A1 (en) | Laboratory instrument and insertable network instrument | |
| CN114062102B (en) | Sample incubation device and sample analyzer | |
| CN208390246U (en) | Compatibility of transfusing blood detection test Incubation centrifuge | |
| CN110361552A (en) | The centrifugal portable microfluidic analysis device of one kind and its application method | |
| CN106290161A (en) | A kind of sample cell for Dynamic Absorption spectra collection | |
| CN209784378U (en) | Qualitative/quantitative biochip reaction instrument | |
| CN102095844A (en) | Biochemical analyzer and biochemical analysis method thereof | |
| CN215178997U (en) | Sample incubation device and sample analyzer | |
| CN206311617U (en) | One kind centrifugation detection Integral small-sized spy's egg analyzer | |
| CN216417220U (en) | Portable device of 24 hours urine specimens of control by temperature change | |
| CN109810893A (en) | A kind of portable agar medium of substance containing temperature sensitive active continuously automatic preparation facilities and method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |