CN207798861U - Sample analysis apparatus and its sample incubation device - Google Patents
Sample analysis apparatus and its sample incubation device Download PDFInfo
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- CN207798861U CN207798861U CN201721030876.6U CN201721030876U CN207798861U CN 207798861 U CN207798861 U CN 207798861U CN 201721030876 U CN201721030876 U CN 201721030876U CN 207798861 U CN207798861 U CN 207798861U
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Abstract
The utility model provides a kind of sample incubation device, including：Driving mechanism, for exporting rotary motion；And it is incubated mechanism, it is set in the driving mechanism, the driving mechanism drives the incubation mechanism rotation；The incubation mechanism includes being incubated disk and multiple reaction cups with ball, opens up multiple putting holes on the incubation disk, multiple reaction cups are installed in multiple putting holes；The driving mechanism drives the incubation mechanism rotation so that the ball moves in the reaction cup, and stirs the liquid in the reaction cup.The sample and reagent that can be stirred to react in cup can be moved in reaction cup under ball centrifugation force effect so that sample is sufficiently mixed with reagent, ensures to be uniformly mixed, and then ensures that testing result is accurate so that sample analysis apparatus plays more preferably function.The utility model also provides a kind of sample analysis apparatus.
Description
Technical field
The utility model is related to technical field of medical equipment, more particularly to a kind of sample analysis apparatus and its sample incubation
Device.
Background technology
In the automatic detection field of medical instrument, the environment for needing to simulate human body when analysis is detected to the extract of human body
Temperature will generally use incubating device.Incubating device is in order to meet increasing inspection demand, generally simultaneously using tray type structure
And more incubation position is arranged on disk.Currently, there are many shapes for reaction cup, also there are many forms for the placement of reaction cup.Often
The band ball container etc. that the reaction cupulate seen has cylindric, square column, cross sectional shape is rectangle, corresponding mode are：
Cylindric or square column is put in circumference array, or array is put in rectangular area；Band ball rectangle reaction cup is in square
Shape is put in region.But incubating device is using above-mentioned reaction cup when coordinating corresponding disposing way to place, the liquid in reaction cup
Body can not mix, and cause mixed effect bad, and then influence testing result.
Utility model content
Based on this, it is necessary to which when being placed for current reaction cup the problem of influence mixed effect, providing one kind can make
The sample incubation device that sample is uniformly mixed with reagent is obtained, while a kind of sample containing above-mentioned sample incubation device point being also provided
Desorption device.
Above-mentioned purpose is achieved through the following technical solutions：
A kind of sample incubation device, including：
Driving mechanism, for exporting rotary motion；And
It is incubated mechanism, is set in the driving mechanism, the driving mechanism drives the incubation mechanism rotation；
The incubation mechanism includes being incubated disk and multiple reaction cups with ball, and multiple placements are opened up on the incubation disk
Hole, multiple reaction cups are installed in multiple putting holes；
The driving mechanism drives the incubation mechanism rotation so that the ball moves in the reaction cup, and stirs
Mix the liquid in the reaction cup.
Each reaction cup is more than described along the size of the radial direction for being incubated disk in one of the embodiments,
Size of the reaction cup along the circumferential direction for being incubated disk.
Each reaction cup is less than described along the size of the radial direction for being incubated disk in one of the embodiments,
Size of the reaction cup along the circumferential direction for being incubated disk.
The cross sectional shape of the reaction cup bottom is arc in one of the embodiments,.
The mechanism that is incubated further includes the heating element for being heated to the incubation disk in one of the embodiments,
The heating element is in contact with the incubation disk.
The mechanism that is incubated further includes the heat preservation for keeping the temperature for being incubated disk in one of the embodiments,
Pot, the incubation disk are set in the fireless cooker, and the heating element is located between the fireless cooker and the incubation disk.
The sample incubation device is in sample analysis apparatus, the sample analysis to be set in one of the embodiments,
Standby corresponding the incubations Pan Chu, which has, to be put glass station and takes a glass station, one of them described putting hole move to described in put a glass work
, one of in remaining described putting hole a glass station is taken in described.
A kind of sample incubation device, including：
Driving mechanism, for exporting rotary motion；And
It is incubated mechanism, is set in the driving mechanism, the driving mechanism drives the incubation mechanism rotation；
The mechanism that is incubated includes being incubated the rectangular reaction cup of disk and multiple cross sections, is opened up on the incubation disk multiple
Putting hole, multiple reaction cups are respectively arranged in the putting hole, and ball, Duo Gesuo are provided in each reaction cup
It states reaction cup to arrange successively along the incubation disk circumferencial direction, the rectangle extending direction of each putting hole is the incubation disk
Radial direction；
The driving mechanism drives the incubation mechanism rotation so that the ball moves in the reaction cup, and stirs
Mix the liquid in the reaction cup.
A kind of sample analysis apparatus includes the transfer dress into cup device, for transfer reaction cup for conveying reaction cup
It sets, the sample testing apparatus for detecting sample and the sample incubation device as described in any of the above-described technical characteristic；
It is described into cup device, the transfer device and the sample testing apparatus station in the one of the sample incubation device
The reaction cup conveyed into cup device can be transferred in the sample incubation device by side, the transfer device, described turn
Reaction cup in the sample incubation device can also be transferred in the sample testing apparatus by moving device.
The sample analysis apparatus further includes retracting device in one of the embodiments, and the retracting device is set to
The side of the sample testing apparatus；
The sample testing apparatus can be detected the reaction cup completed and be transferred to the recycling by the transfer device
In device.
The retracting device, which has, in one of the embodiments, loses rim of a cup, described to have into cup device into rim of a cup, described
There is sample analysis apparatus glass station of putting for corresponding to the sample incubation device setting, the sample testing apparatus to have detection work
Position, it is described into rim of a cup, it is described lose rim of a cup, it is described put a glass station, the detection station is collinearly arranged, and the corresponding transfer device
Movement locus.
After adopting the above technical scheme, the beneficial effects of the utility model are：
The sample analysis apparatus and its sample incubation device of the utility model, the reaction cup with ball are placed on putting hole
In, such driving mechanism drives the incubation disk for being incubated mechanism to rotate and will produce centrifugal force, so that in reaction cup
Ball is under the influence of centrifugal force in reaction cup；Effective solution current reaction cup influences asking for mixed effect when placing
Topic, ball move the sample and reagent that can be stirred to react in cup in reaction cup so that sample is sufficiently mixed with reagent, is ensured
It is uniformly mixed, and then ensures that testing result is accurate so that sample analysis apparatus plays more preferably function.
Description of the drawings
Fig. 1 is that the sample incubation device of one embodiment of the utility model removes the stereogram of lid；
Fig. 2 is the vertical view of sample incubation device shown in FIG. 1；
Fig. 3 is the schematic cross-sectional view of sample incubation device shown in FIG. 1；
Fig. 4 is the partial enlarged view at A shown in Fig. 3；
Fig. 5 is that sample incubation device shown in Fig. 2 adds lid vertical view；
Fig. 6 is the vertical view that sample incubation device shown in Fig. 2 removes reaction cup；
Fig. 7 is the flow chart for being incubated disk and executing forced oscillation；
Wherein：
100- sample incubation devices；
110- driving mechanisms；
111- driving motors；
112- transmission parts；
120- is incubated mechanism；
121- is incubated disk；
1211- putting holes；
122- heating elements；
123- fireless cookers；
124- reaction cups；
1241- balls；
130- lids.
Specific implementation mode
In order to make the purpose of the utility model, technical solutions and advantages more clearly understood, by the following examples, it and ties
Attached drawing is closed, sample analysis apparatus and its sample incubation device to the utility model are further elaborated.It should be appreciated that
Specific embodiment described herein only to explain the utility model, is not used to limit the utility model.
" connection ", " connection " described in the application include unless otherwise instructed directly or indirectly connecting (connection).At this
In the description of utility model, it is to be understood that term "upper", "lower", "front", "rear", "left", "right", "vertical", " water
It is flat ", "top", "bottom", "inner", "outside", " clockwise ", the orientation or positional relationship of the instructions such as " counterclockwise " is based on shown in attached drawing
Orientation or positional relationship, be merely for convenience of describing the present invention and simplifying the description, do not indicate or imply the indicated
Device or element must have a particular orientation, with specific azimuth configuration and operation, therefore should not be understood as new to this practicality
The limitation of type.
In the present invention unless specifically defined or limited otherwise, fisrt feature is "above" or "below" second feature
Can be that the first and second features are in direct contact or the first and second features pass through intermediary mediate contact.Moreover, first is special
Sign second feature " on ", " top " and " above " can be fisrt feature and be directly above or diagonally above the second feature, or only
Indicate that fisrt feature level height is higher than second feature.Fisrt feature second feature " under ", " lower section " and " below " can be with
It is that fisrt feature is directly under or diagonally below the second feature, or is merely representative of fisrt feature level height and is less than second feature.
Referring to Fig. 1, Fig. 2 and Fig. 6, Fig. 1 is that the sample incubation device 100 of one embodiment of the utility model removes lid 130
Stereogram, Fig. 2 be sample incubation device 100 shown in FIG. 1 vertical view, Fig. 6 be sample incubation device 100 shown in Fig. 2
Remove the vertical view of reaction cup 124.The utility model provides a kind of sample incubation device 100, which answers
For in sample analysis apparatus, reaction cup 124 of the sample incubation device 100 installation with ball 1421 to be used for sample to be measured
This is heated to about 37 DEG C with reagent before formal measure, and to be incubated to the sample in reaction cup 124, and then ensures reaction
It is normally carried out.It should be noted that the specific type of sample to be measured is unrestricted, and in some embodiments, sample to be measured
Including solid sample or liquid sample.It is appreciated that when being detected liquid sample, need liquid sample being placed in sample
It could be carried out on frame.Further liquid sample includes but not limited to blood sample.It is filled using the sample incubation of the utility model
When setting 100 pairs of samples and being incubated, sample is enabled to be sufficiently mixed with reagent, ensure to be uniformly mixed, and then ensures detection knot
Fruit is accurate so that sample analysis apparatus plays more preferably function.
In the present invention, sample incubation device 100 includes driving mechanism 110 and incubation mechanism 120.It is incubated mechanism
120 are set in driving mechanism 110, are incubated mechanism 120 and are used for being incubated sample, driving mechanism 110, which is used for driving, is incubated mechanism 120
Rotation so that be incubated mechanism 120 and move to corresponding position so that sample analysis apparatus executes accordingly to being incubated mechanism 120
Operation.Driving mechanism 110 can export rotary motion, and then incubation mechanism 120 is driven to rotate.It enables to incubate in this way
It educates mechanism 120 and generates centrifugal force, so that the sample being incubated in mechanism 120 is uniformly mixed under the action of the centrifugal force with reagent.
Specifically, it includes being incubated disk 121 and multiple reaction cups 124 with ball 1421 to be incubated mechanism 120, it is incubated disk 121
On open up multiple putting holes 1211, multiple reaction cups 124 are respectively installed in multiple putting holes 1211.Driving mechanism 110 with incubate
The drive connection of disk 121 is educated, driving mechanism 110 can drive incubation disk 121 to rotate.Sample incubation device 100 is to sample
When this carries out being incubated operation, sample and reagent are by the puncture needle mechanism of sample analysis apparatus, comprehensive needle mechanism and reagent needle machine
Structure is transferred in each reaction cup 124 of sample incubation device 100.When driving mechanism 110 drives incubation disk 121 to rotate, it is incubated
Disk 121 can drive the reaction cup 124 in putting hole 1211 thereon to rotate together, and then the ball 1421 in reaction cup 124 exists
The reciprocally swinging in reaction cup 124 is incubated under the centrifugation force effect that the rotation of disk 121 generates, with the sample being stirred to react in cup 124
With reagent, the operation of mixing sample and reagent is realized.Preferably, ball 1421 can be steel ball.Optionally, it is incubated disk 121
Shape setting in disk form avoids other parts of sample analysis apparatus when such driving structure drives incubation disk 121 to rotate
It is interfered with disk 121 is incubated, the whole installation of convenience sample analytical equipment.Certainly, in other embodiment party of the utility model
In formula, incubation disk 121 can also be square, oval or other can drive the shape that reaction cup 124 rotates thereon.
The centrifugal force that the driving of driving mechanism 110 is incubated the incubation disk 121 rotation generation of mechanism 120 enables to ball 1421
Reciprocally swinging is stirred to react sample and reagent in cup 124 in reaction cup 124.In addition, driving mechanism 110 is incubated disk in driving
Inertia force is will produce when 121 startups and shutdown, when speed change rotation, ball 1421 also can be in reaction cup under the action of inertia force
Reciprocally swinging in 124, to be stirred to react the sample and reagent in cup 124.Optionally, driving mechanism 110 exports reciprocating rotary
Transhipment is dynamic, and then incubation mechanism 120 is driven to do crankmotion, by being incubated the reciprocally swinging of disk 121, can increase sample
With the mixed effect of reagent.Certainly, in the other embodiment of the utility model, the also exportable unidirectional rotation of driving mechanism 110
Transhipment is dynamic, and then incubation mechanism 120 is driven to do unidirectional rotary motion.
Preferably, multiple putting holes 1211 are set gradually on the circumferencial direction for being incubated disk 121.Sample is enabled in this way
Incubating device 100 is simultaneously incubated multiple samples, improves operating efficiency.Multiple reaction cups 124 are respectively installed to multiple put
It sets in hole 1211.Moreover, after the reaction cup 124 being incubated on disk 121 is diverted, it can also retransfer new reaction cup 124 and place
Into putting hole 1211.
Can be that each reaction cup 124 is more than reaction cup 124 along incubation disk along the size for the radial direction for being incubated disk 121
The size of 121 circumferential direction.Here reaction cup 124 refers to that reaction cup 124 is pacified along the size for the radial direction for being incubated disk 121
Be attached to be incubated disk 121 putting hole 1211 in reaction cup 124 along be incubated 121 radial direction of disk length dimension；124 edge of reaction cup
The size for being incubated the circumferential direction of disk 121 refers to that reaction cup 124 is installed to reaction cup 124 in the putting hole 1211 for being incubated disk 121
Along the length dimension for being incubated 121 circumferential direction of disk.The length dimension of the radial direction of each reaction cup 124 is more than circumferential direction
Length dimension, that is to say, that modes of emplacement of each reaction cup 124 on being incubated disk 121 is the length dimension side of reaction cup 124
To being extended along the radial direction for being incubated disk 121, multiple reaction cups 124 are extended in a radial direction on being incubated disk 121 and edge
Circumferencial direction is arranged successively.Since the size of reaction cup 124 radially is more than the size of circumferential direction so that ball 1421
Radially there is certain space in reaction cup 124.It is rotated in this way, the driving of driving mechanism 110 is incubated disk 121 and does
When movement, it is incubated the centrifugal force that disk 121 will produce radial direction, ball 1421 can be in reaction cup under radial centrifugation force effect
Space reciprocally swinging in 124 radially, to be stirred to react the sample and reagent in cup 124 so that sample and reality
Border is uniformly mixed.Meanwhile the length direction of multiple reaction cups 124 can also to be incubated disk 121 along radially extending for disk 121 is incubated
It is compact-sized, it is easy to accomplish scheduling.
It can also be that each reaction cup 124 is less than reaction cup 124 along incubation disk along the size for the radial direction for being incubated disk 121
The size of 121 circumferential direction.Here reaction cup 124 refers to that reaction cup 124 is pacified along the size for the radial direction for being incubated disk 121
Be attached to be incubated disk 121 putting hole 1211 in reaction cup 124 along be incubated 121 radial direction of disk length dimension；124 edge of reaction cup
The size for being incubated the circumferential direction of disk 121 refers to that reaction cup 124 is installed to reaction cup 124 in the putting hole 1211 for being incubated disk 121
Along the length dimension for being incubated 121 circumferential direction of disk.The length dimension of the radial direction of each reaction cup 124 is less than circumferential direction
Length dimension, that is to say, that modes of emplacement of each reaction cup 124 on being incubated disk 121 is the length dimension side of reaction cup 124
To being extended along the circumferential direction for being incubated disk 121, multiple reaction cups 124 extend along circumferential direction on being incubated disk 121 and edge
Circumferencial direction is arranged successively.Since the size of reaction cup 124 radially is less than the size of circumferential direction so that ball 1421
There is certain space along circumferential direction in reaction cup 124.In this way, driving mechanism 110 drives incubation disk 121 to rotate
The inertia force generated is moved it is also possible that space reciprocally swinging of the ball 1421 in reaction cup 124 along circumferential direction,
To be stirred to react the sample and reagent in cup 124 so that sample is uniformly mixed with reagent.
Certainly, in the other embodiment of the utility model, reaction cup 124 can also embark on journey in column or be arranged with other
Form setting be incubated disk 121 on, by driving mechanism 110 drive be incubated disk 121 rotate generation centrifugal force and/or
Inertia force realizes reciprocally swinging of the ball 1421 in reaction cup 124, realizes that sample is uniformly mixed with reagent.It needs to illustrate
It is that the shape of putting hole 1211 can be identical as the shape of reaction cup 124, to ensure that reaction cup 124 is reliably mounted at placement
In hole 1211.If the cross sectional shape of reaction cup 124 and putting hole 1211 can be rectangle, circle, ellipse or other energy
Enough realize the shape etc. that ball 1421 moves.In the present embodiment, reaction cup 124 and the cross sectional shape of putting hole 1211 are
Rectangle.Certainly, in the other embodiment of the utility model, the shape of putting hole 1211 also can be with the shape of reaction cup 124
Difference, as long as reaction cup 124 can be fixed in putting hole 1211.Such as 1211 cross sectional shape of putting hole is
The cross sectional shape of rectangle, reaction cup 124 can be ellipse, the round, rectangle etc. smaller than the area of section of putting hole 1211.
Referring to Fig. 3 and Fig. 4, Fig. 3 is the schematic cross-sectional view of sample incubation device 100 shown in FIG. 1, and Fig. 4 is Fig. 3 institutes
The partial enlarged view at A shown.Optionally, the arc-shaped shape in 124 bottom of reaction cup.Bottom, which is the reaction cup 124 of arc, to rise
To the effect of guiding, increases inertia force when ball 1421 is swung, be further ensured that the sample in reaction cup 124 is mixed with reagent
Uniformly.Moreover, reaction cup 124 is radially set in the putting hole 1211 for being incubated disk 121, reaction cup 124 is circumferentially square
To width dimensions can be adapted with the diameter of ball 1421, enable to ball 1421 under the action of the centrifugal force can only in this way
Radially moving, the displacement of limitation ball 1421 along circumferential direction avoids ball 1421 from being glanced off in swing process,
Ensure mixed effect.Meanwhile the reaction cup 124 of arc-shaped shape can also make the movement of ball 1421 there are the displacement of upper and lower directions,
Enhance mixed effect.
In general, sample analysis apparatus is when to addition sample and reagent in the reaction cup 124 of disk 121 is incubated, usual sample
With reagent added in reaction cup 124 close to the marginal position for being incubated 121 outside of disk, such driving mechanism 110 is being incubated disk
When 121 rotation, ball 1421, sample and reagent in reaction cup 124 can be under the action of the centrifugal force to the outer sidesways for being incubated disk 121
Dynamic, the movement of ball 1421 mixes the sample in reaction cup 124 with reagent.
Further, it further includes the heating element 122 for being heated to being incubated disk 121, heating element to be incubated mechanism 120
122 are in contact with disk 121 is incubated.Heating element 122 is used for the sample to being incubated in the reaction cup 124 of disk 121 and reagent progress
Heating so that the temperature of sample and reagent in reaction cup 124 reaches preset temperature, such as 37 DEG C or so, with to reaction cup 124
In sample be incubated, and then ensure reaction be normally carried out.Preferably, heating element 122 can be heating film, heating film patch
In the bottom for being incubated disk 121.Certainly, in the other embodiment of the utility model, heating element 122 can also be heater strip
Or other can realize the structure of heating.Moreover, being incubated the heat preservation that mechanism 120 further includes the temperature for keeping being incubated disk 121
Pot 123 is incubated disk 121 and is set in fireless cooker 123, and heating element 122 is located at fireless cooker 123 and is incubated between disk 121.Heat preservation
Pot 123 can play insulation effect to the incubation disk 121 after heating so that the temperature of sample and reagent in reaction cup 124 is protected
Hold it is constant so that be incubated disk 121 sample in reaction cup 124 is incubated, ensure reaction is normally carried out.
Referring to Fig. 1 and Fig. 5, Fig. 5 is that sample incubation device 100 shown in Fig. 2 adds 130 vertical view of lid.As one kind
Embodiment, sample incubation device 100 are used in sample analysis apparatus, and sample analysis apparatus, which corresponds to incubation Pan121Chu, to be had
It puts glass station and takes a glass station, one of putting hole 1211, which moves to, puts a glass station, location A as shown in Figure 5, remaining placement
It is in one of in hole 1211 and takes a glass station, B location as shown in Figure 5.Sample analysis apparatus will be anti-by transfer device
Answer cup 124 from be transferred into from cup device be incubated disk 121 on, then by reaction cup 124 from be incubated disk 121 on be transferred to pattern detection
On device, reaction cup 124 is transferred to be incubated on disk 121 and be carried out on putting glass station by transfer device, and transfer device will be anti-
It is that glass station is being taken to carry out to answer cup 124 to be moved away from incubation disk 121.Moreover, transfer device include the first transfer device and
Second transfer device, the first transfer device put a glass station for reaction cup 124 to be transferred to, and the second transfer device is used for will be anti-
Cup 124 is answered to be moved away from incubation disk 121；Also, in order to make full use of the first transfer device and the second transfer device, improve behaviour
Make efficiency, the first transfer device can also move away the reaction cup 124 put in glass station.
When driving mechanism 110 drives incubation disk 121 to rotate, putting hole one of on incubation disk 121
1211 move to and put a glass station, and one in remaining putting hole 1211, which just moves to, takes a glass station, at this point, the first transfer device
Glass station placing response cup 124 can put or taking out the reaction cup 124 in putting hole 1211, meanwhile, the second transfer device
The reaction cup 124 in the corresponding putting hole of glass station 1211 can will be taken to take out.The first transfer device and are enabled in this way
Two transfer devices are carried out at the same time operation, while facilitating the first transfer device and the second transfer device captures, improve operation effect
Rate.Preferably, the angle for taking glass station and putting between glass station relative to the center of circle for being incubated disk 121 is 90 °, to facilitate first turn
Telephone-moving structure and the second transfer device capture.Certainly, it in the other embodiment of the utility model, takes glass station and puts a glass station
Between angle can also be other angles, as long as can adapt to the first transfer device and the second transfer device.
Further, sample analysis apparatus also has stirring station, location of C as shown in Figure 5.Sample analysis apparatus is stirring
Mix station setting agitating device, the sample in reaction cup 124 is mixed with reagent by agitating device, be further ensured that sample and
Reagent is uniformly mixed.
Sample incubation device 100 further includes supporting rack, and supporting rack is used to support fireless cooker 123.Moreover, sample incubation device
100 further include lid 130, and the lid of lid 130 is located on fireless cooker 123, reagent adding station is reserved on lid 130, is loaded this work
Position takes a glass station, puts glass station and stirring station, and corresponding operation carries out on corresponding station, avoids maloperation and pollute
Sample in reaction cup 124 and reagent ensure that reaction is accurate.
As a kind of embodiment, driving mechanism 110 includes driving motor 111 and is installed on driving motor 111
Transmission parts 1112.1112 drive connection driving motor 111 of transmission parts and incubation disk 121,121 reciprocating rotary of disk is incubated with driving
Turn.One end of transmission parts 1112 is sequentially connected with disk 121 is incubated, the other end and the driving motor 111 of transmission parts 1112
Output end is sequentially connected, and such driving motor 111 can drive transmission parts 1112 to move, and then drives to be incubated disk 121 and do and revolve
Transhipment is dynamic, so that being incubated the generation centrifugal force of disk 121 and the sample in hybrid reaction cup 124 and reagent.Driving motor 111 drives
It is incubated disk 121 to rotate so that incubation disk 121 drives reaction cup 124 thereon to turn to and takes a glass station, is loaded this station, additional examination
Agent station and a glass station is put, and executes corresponding operation.Transmission parts 1112 may be used synchronous belt transfer assembly or other
It can realize the component that movement is transmitted, such as lead screw, sprocket wheel structure.
The utility model additionally provides a kind of sample incubation device 100, includes the driving mechanism for exporting rotary motion
110 and be incubated mechanism 120.Driving mechanism 110 is set in driving mechanism 110, and driving mechanism 110, which drives, is incubated 120 turns of mechanism
It is dynamic.It is incubated mechanism 120 and includes the rectangular reaction cup 124 of incubation disk 121 and multiple cross sections, opened up on incubation disk 121 multiple
Putting hole 1211, multiple reaction cups 124 are respectively arranged in putting hole 1211, and ball 1421 is provided in each reaction cup 124,
Multiple reaction cups 124 are arranged successively along 121 circumferencial direction of disk is incubated, and the rectangle extending direction of each putting hole 1211 is to be incubated disk
121 radial direction.Driving mechanism 110, which drives, is incubated the rotation of mechanism 120 so that and ball 1421 moves in reaction cup 124, and
The liquid being stirred to react in cup 124.
The reaction cup 124 of rectangular band ball 1421 is placed in putting hole 1211, radially due to putting hole 1211
Extend, the length of putting hole 1211 radially is more than width along circumferential direction in addition, and the drive of such driving mechanism 110 is incubated
When educating the incubation disk 121 of mechanism 120 and rotating, ball 1421 in reaction cup 124 can by under centrifugation force effect anti-
It answers and is radially moved in cup 124, enable to ball 1421 that radially there is enough spaces, it being capable of mixing
Sample in reaction cup 124 and reagent ensure that testing result is accurate.Meanwhile the sample incubation device 100 of the utility model can
The circumference on being incubated disk 121 of reaction cup 124 is set to put successively so that sample incubation device 100 is compact-sized, it is easy to accomplish adjusts
Degree so that sample analysis apparatus performance more preferably more can.It should be noted that driving mechanism 110 be incubated mechanism 120 it is specific
The driving mechanism 110 and incubation mechanism in sample incubation device 100 in structure, position and movement relation and above-described embodiment
120 is identical, does not just repeat one by one herein.
The utility model additionally provides a kind of control method of sample incubation device 100, is applied to such as the sample in embodiment
The controlling party of this incubating device 100, sample incubation device 100 includes the following steps：
Obtain the current location information for being incubated 121 one of putting hole 1211 of disk；
Obtain the target position information of putting hole 1211；
Disk 121 is incubated in current location information and target position information driving turn to target position according to putting hole 1211
It sets.
When carrying out sample operations, first obtaining incubation disk 121, one of them puts the sample incubation device 100 of the utility model
The current location information in hole 1211 is set, that is, obtains and is incubated 121 one of putting hole 1211 of disk relative to the initial of incubation disk 121
The information of position；Then the putting hole 1211 is determined according to the putting hole 1211 next step to be executed operation on incubation disk 121
Target position information, that is, be incubated disk 121 initial position will turn to the next position information be initial position with respect to mesh
The information of cursor position；Further according to the rotation of the current location information and target position information determination incubation disk 121 of putting hole 1211
Displacement, driving mechanism 110 are incubated disk 121 according to the rotation displacement driving of incubation disk 121 and rotate so that are incubated being somebody's turn to do on disk 121
Putting hole 1211 turns to target location, and executes corresponding operation.
Specifically, target location refers to putting a glass station, taking a glass station, sample-adding station, reagent adding station for sample analysis apparatus
And stirring station.Incubation disk 121 drives putting hole 1211 to turn to and puts a glass station, and sample analysis apparatus execution puts cup or cup is taken to grasp
Make.Incubation disk 121 drives putting hole 1211 to turn to and takes a glass station, and sample analysis apparatus execution takes cup to operate.It is incubated 121 band of disk
Dynamic putting hole 1211 turns to sample-adding station, and sample analysis apparatus executes plus sample operations.It is incubated disk 121 and drives putting hole 1211
Reactant station is turned to plus spits, sample analysis apparatus executes reagent adding operation.Incubation disk 121 drives putting hole 1211 to turn to and stirs
Station is mixed, sample analysis apparatus executes stirring operation.It putting a glass station moreover, the driving of driving mechanism 110 is incubated disk 121, taking cup
When being rotated between station, sample-adding station, reagent adding station and stirring station, it is incubated disk 121 and will produce centrifugal force, so that putting
The reciprocally swinging in reaction cup 124 of the ball 1421 in hole 1211 is set, to be stirred to react the sample and reagent in cup 124 so that
Sample is uniformly mixed with reagent.It should be noted that when the initial position for being incubated disk 121 refers to sample analysis apparatus booting, incubate
Educate 1211 corresponding zero-bit of one of disk 121 putting hole.
Further, current location information refer to putting hole 1211 current location be incubated 121 initial position of disk and incubate
Educate the first central angle that the center of circle of disk 121 is formed, target position information refers to target location and incubation 121 initial position of disk and incubate
The second central angle that the center of circle of disk 121 is formed is educated, is driven according to the difference of the first central angle and the second central angle and is incubated 121 turns of disk
It moves to target location.Sample incubation device 100, which first obtains, is incubated disk 121 putting hole 1211 and initial position at current location
Relative to the first central angle that the center of circle for being incubated disk 121 is formed, target position will be moved to by then obtaining the putting hole 1211 again
The second central angle that target location is formed with initial position relative to the center of circle for being incubated disk 121 when setting, then pass through the second central angle
The difference of target location and current location is obtained with the difference of the first central angle, driving mechanism 110 drives according to difference and is incubated disk
121 rotations so that the putting hole 1211 being incubated on disk 121 turns to target location.
Optionally, as shown in fig. 7, Fig. 7 is the flow chart for being incubated disk 121 and executing forced oscillation.Sample incubation device 100
Control method further includes following steps：
Step S1：Obtain the signal being incubated when disk 121 is in idle condition；
Step S2：Driving is incubated one of disk 121 putting hole 1211 and turns to the first swing along the first rotation direction
Position；
Step S3：It is incubated 121 static preset time of disk；
Step S4：The putting hole 1211 that driving is incubated disk 121 turns to the second swing position along the second rotation direction.
When being incubated 121 proper motion of disk, the driving of driving mechanism 110 is incubated disk 121 and rotates, and moves to each operation position
Execute corresponding operation.Driving mechanism 110 is incubated when disk 121 rotates in driving and also will produce certain mixed effect,
When being incubated 121 free time of disk, being incubated disk 121 will not rotate, and the ball 1421 in reaction cup 124 will not be in outer force effect at this time
Lower stirring sample and reagent.In order to increase the mixed effect of sample and reagent, the driving of driving mechanism 110 is incubated disk 121 and executes
Operation is stated, is i.e. when the putting hole 1211 of incubation disk 121 moves to the first swing position and the second swing position, is incubated disk 121 and holds
Row forced oscillation operates.It is incubated disk 121 during idle time, driving mechanism 110 can drive incubation disk 121 to do pressure swinging operation, make
Disk 121 must be incubated to rotate in fireless cooker 123, the ball 1421 being incubated in the reaction cup 124 of disk 121 under the action of the centrifugal force can
Sample and reagent in enough hybrid reaction cups 124, increase mixed effect.It should be noted that preset time refer to be incubated disk 121 to
Pause 1s less.
It should be noted that the first swing position can be any position for being incubated disk 121 with the second swing position, that is, incubate
It can be any position for being incubated disk 121 to educate the starting position rotated when 121 free time of disk, be incubated the knot rotated when 121 free time of disk
Beam position can be any position for being incubated disk 121, can increase the mixing of sample and reagent in reaction cup 124 in this way.First
Rotation direction can be same direction or opposite direction with the second rotation direction, and driving mechanism 110 exports single direction rotation fortune
When dynamic, the first rotation direction and the second rotation direction can be same direction.When driving mechanism 110 exports crankmotion,
First rotation direction and the second rotation direction can be opposite direction.Preferably, the first swing position is to put a glass station, the second pendulum
Dynamic position is stirring station.In this way in the case of existing resource component actuation and parameter constant, make incubation disk 121 in two phases
It swings away from the farthest position in position, so that the swinging distance for being incubated disk 121 is maximum, can speed up so that being incubated disk 121
It is run to maximum speed.The ball 1421 in reaction cup 124 has time enough to move under the action of the centrifugal force with sample at this time
To the outside of reaction cup 124, ensure mixing effect.
Optionally, the forced oscillation operation for being incubated disk 121 is also used as being incubated the correct operation of disk 121.It is incubated disk 121
Timing, the first swing position are incubated 121 initial position of disk with one in the second swing position.Driving mechanism 110 drives
It is incubated to exist when disk 121 rotates and loses step phenomenon, the calibrating coordinates that forced oscillation operation setting is incubation disk 121 are moved
Make, mixing can either be played the role of, and accumulative step of losing can be eliminated and ensure that coordinate is accurate.
The utility model additionally provides a kind of sample analysis apparatus, include for convey reaction cup 124 into cup device, use
Sample in the transfer device, sample testing apparatus and above-described embodiment for detecting sample of transfer reaction cup 124 is incubated
Educate device 100.Reaction cup 124 into cup device for conveying improves conveying to realize the automatic conveying of empty reaction cup 124
Efficiency.Transfer device is used for transfer reaction cup 124, so that reaction cup 124 can move to each position of sample analysis apparatus
It sets, realizes the detection that automatically analyzes of sample, improve operating efficiency.Sample testing apparatus is for detecting sample, to obtain sample
Corresponding parameter.Into cup device, transfer device and sample testing apparatus station in the side of sample incubation device 100, transfer device
The reaction cup 124 conveyed into cup device can be transferred in the incubation disk 121 of sample incubation device 100, transfer device can also
Reaction cup 124 in sample incubation device 100 is transferred in sample testing apparatus.
Further, sample analysis apparatus further includes retracting device, and retracting device is set to the side of sample testing apparatus.
Sample testing apparatus can be detected the reaction cup 124 completed and is transferred in retracting device by transfer device.Retracting device recycling inspection
The reaction cup 124 surveyed, avoid sample and the reagent sinuous flow in reaction cup 124 from leading to environmental pollution.
Still further, retracting device, which has, loses rim of a cup, have into cup device into rim of a cup, sample analysis apparatus, which has, to be corresponded to
What sample incubation device 100 was arranged puts a glass station, and sample testing apparatus has detection station, into rim of a cup, loses rim of a cup, puts a glass work
Position, detection station are collinearly arranged, and the movement locus of corresponding transfer device.Shift module is in the reaction into rim of a cup crawl sky in this way
Cup 124, and it is transferred to the putting on glass station of sample incubation module；Shift module can also take out reaction cup 124 on putting glass station,
And reaction cup 124 is transferred in pattern detection module and is detected, after the completion of detection, detection module will be in pattern detection module
Reaction cup 124 be transferred to and lose in rim of a cup.Take empty cup station, lose rim of a cup, put a glass station, detection station collinearly setting enable to
Shift module saves shift module the space occupied, and then reduce sample analysis in the same direction toward straight reciprocating motion is done
The package size of equipment, while shift module moves in a straight line and is also avoided that shift module or other parts interfere,
Ensure the reliability of movement.
Each technical characteristic of embodiment described above can be combined arbitrarily, to keep description succinct, not to above-mentioned reality
It applies all possible combination of each technical characteristic in example to be all described, as long as however, the combination of these technical characteristics is not deposited
In contradiction, it is all considered to be the record scope of this specification.
Above-described embodiments merely represent several embodiments of the utility model, the description thereof is more specific and detailed,
But it should not be understood as limiting the scope of the patent of the utility model.It should be pointed out that for the common of this field
For technical staff, without departing from the concept of the premise utility, various modifications and improvements can be made, these all belong to
In the scope of protection of the utility model.Therefore, the protection domain of the utility model patent should be determined by the appended claims.
Claims (11)
1. a kind of sample incubation device, which is characterized in that including：
Driving mechanism, for exporting rotary motion；And
It is incubated mechanism, is set in the driving mechanism, the driving mechanism drives the incubation mechanism rotation；
The incubation mechanism includes being incubated disk and multiple reaction cups with ball, and multiple putting holes are opened up on the incubation disk,
Multiple reaction cups are installed in multiple putting holes；
The driving mechanism drives the incubation mechanism rotation so that the ball moves in the reaction cup, and stirs institute
State the liquid in reaction cup.
2. sample incubation device according to claim 1, which is characterized in that each reaction cup is along the incubation disk
The size of radial direction is more than size of the reaction cup along the circumferential direction for being incubated disk.
3. sample incubation device according to claim 1, which is characterized in that each reaction cup is along the incubation disk
The size of radial direction is less than size of the reaction cup along the circumferential direction for being incubated disk.
4. sample incubation device according to claim 1, which is characterized in that the arc-shaped shape in reaction cup bottom.
5. sample incubation device according to any one of claims 1 to 4, which is characterized in that the incubation mechanism further includes
For the heating element to the incubation disk heating, the heating element is in contact with the incubation disk.
6. sample incubation device according to claim 5, which is characterized in that the incubation mechanism further includes for keeping
The fireless cooker for the temperature for being incubated disk is stated, the incubation disk is set in the fireless cooker, and the heating element is located at the heat preservation
Between pot and the incubation disk.
7. sample incubation device according to claim 1, which is characterized in that the sample incubation device is used for sample analysis
In equipment, the sample analysis apparatus, which corresponds to the incubation Pan Chu and has, to be put glass station and takes a glass station, is put described in one of them
Set hole move to it is described put a glass station, take a glass station in described one of in remaining described putting hole.
8. a kind of sample incubation device, which is characterized in that including：
Driving mechanism, for exporting rotary motion；And
It is incubated mechanism, is set in the driving mechanism, the driving mechanism drives the incubation mechanism rotation；
The mechanism that is incubated includes being incubated the rectangular reaction cup of disk and multiple cross sections, and multiple placements are opened up on the incubation disk
Hole, multiple reaction cups are respectively arranged in the putting hole, and ball is provided in each reaction cup, multiple described anti-
Incubation disk circumferencial direction described in cup edge is answered to arrange successively, the rectangle extending direction of each putting hole is the diameter for being incubated disk
To direction；
The driving mechanism drives the incubation mechanism rotation so that the ball moves in the reaction cup, and stirs institute
State the liquid in reaction cup.
9. a kind of sample analysis apparatus, which is characterized in that include for convey reaction cup into cup device, be used for transfer reaction cup
Transfer device, the sample testing apparatus for detecting sample and sample incubation as described in any one of claim 1 to 7 dress
It sets；
It is described into cup device, the transfer device and the sample testing apparatus station in the side of the sample incubation device,
The reaction cup conveyed into cup device can be transferred in the sample incubation device by the transfer device, the transfer dress
Setting can also be transferred to the reaction cup in the sample incubation device in the sample testing apparatus.
10. sample analysis apparatus according to claim 9, which is characterized in that the sample analysis apparatus further includes recycling
Device, the retracting device are set to the side of the sample testing apparatus；
The sample testing apparatus can be detected the reaction cup completed and be transferred to the retracting device by the transfer device
In.
11. sample analysis apparatus according to claim 10, which is characterized in that the retracting device, which has, loses rim of a cup, institute
Stating has into cup device into rim of a cup, and the sample analysis apparatus puts a glass station with the corresponding sample incubation device setting,
The sample testing apparatus has a detection station, it is described into rim of a cup, described lose rim of a cup, described put a glass station, the detection station
Conllinear setting, and the movement locus of the corresponding transfer device.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721030876.6U CN207798861U (en) | 2017-08-16 | 2017-08-16 | Sample analysis apparatus and its sample incubation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721030876.6U CN207798861U (en) | 2017-08-16 | 2017-08-16 | Sample analysis apparatus and its sample incubation device |
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| CN207798861U true CN207798861U (en) | 2018-08-31 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109406810A (en) * | 2017-08-16 | 2019-03-01 | 北京普利生仪器有限公司 | Sample analysis apparatus, sample incubation device and its control method |
| WO2020087255A1 (en) * | 2018-10-30 | 2020-05-07 | 深圳迎凯生物科技有限公司 | Dilution method, dilution device and immunoassay analyzer |
| CN111122886A (en) * | 2018-10-30 | 2020-05-08 | 深圳迎凯生物科技有限公司 | Dilution method, dilution device, and immunoassay analyzer |
| CN112230008A (en) * | 2020-12-18 | 2021-01-15 | 南京澳林生物科技有限公司 | Portable POCT full-automatic biochemical analyzer and use method thereof |
| CN114062067A (en) * | 2020-07-30 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Sample incubation device and sample analyzer |
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2017
- 2017-08-16 CN CN201721030876.6U patent/CN207798861U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109406810A (en) * | 2017-08-16 | 2019-03-01 | 北京普利生仪器有限公司 | Sample analysis apparatus, sample incubation device and its control method |
| WO2020087255A1 (en) * | 2018-10-30 | 2020-05-07 | 深圳迎凯生物科技有限公司 | Dilution method, dilution device and immunoassay analyzer |
| CN111122886A (en) * | 2018-10-30 | 2020-05-08 | 深圳迎凯生物科技有限公司 | Dilution method, dilution device, and immunoassay analyzer |
| CN111122886B (en) * | 2018-10-30 | 2023-08-08 | 深圳迎凯生物科技有限公司 | Dilution method, dilution device and immunoassay instrument |
| CN114062067A (en) * | 2020-07-30 | 2022-02-18 | 深圳市帝迈生物技术有限公司 | Sample incubation device and sample analyzer |
| CN114062067B (en) * | 2020-07-30 | 2024-04-19 | 深圳市帝迈生物技术有限公司 | Sample incubation device and sample analyzer |
| CN112230008A (en) * | 2020-12-18 | 2021-01-15 | 南京澳林生物科技有限公司 | Portable POCT full-automatic biochemical analyzer and use method thereof |
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Address after: 102200 1st, 2nd, 4th and 5th floors, building 3, No. 18, kekeyuan Road, Life Science Park, Changping District, Beijing Patentee after: Beijing Mindray Medical Instrument Co.,Ltd. Address before: 100000 East, second floor, building 5, Shangdi Qunying Science Park, Haidian District, Beijing Patentee before: BEIJING PRECIL INSTRUMENT Co.,Ltd. |
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