CN1140078A - Formula of dizzy-eliminating and dizziness-stopping tablet and its production process - Google Patents
Formula of dizzy-eliminating and dizziness-stopping tablet and its production process Download PDFInfo
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- CN1140078A CN1140078A CN 95119066 CN95119066A CN1140078A CN 1140078 A CN1140078 A CN 1140078A CN 95119066 CN95119066 CN 95119066 CN 95119066 A CN95119066 A CN 95119066A CN 1140078 A CN1140078 A CN 1140078A
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 10
- 208000002173 dizziness Diseases 0.000 title abstract description 18
- 239000003814 drug Substances 0.000 claims abstract description 33
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 4
- 239000000843 powder Substances 0.000 claims abstract description 3
- 206010042772 syncope Diseases 0.000 claims description 8
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 5
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 5
- 239000004615 ingredient Substances 0.000 claims description 5
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 229920002472 Starch Polymers 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 4
- 235000019698 starch Nutrition 0.000 claims description 4
- 239000008107 starch Substances 0.000 claims description 4
- 229920001353 Dextrin Polymers 0.000 claims description 2
- 239000004375 Dextrin Substances 0.000 claims description 2
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 238000001816 cooling Methods 0.000 claims description 2
- 235000019425 dextrin Nutrition 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims description 2
- 238000002386 leaching Methods 0.000 claims description 2
- 235000019359 magnesium stearate Nutrition 0.000 claims description 2
- 239000000047 product Substances 0.000 claims description 2
- 239000007921 spray Substances 0.000 claims description 2
- 238000001256 steam distillation Methods 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 238000009495 sugar coating Methods 0.000 claims description 2
- 239000006228 supernatant Substances 0.000 claims description 2
- 208000012886 Vertigo Diseases 0.000 abstract description 4
- 238000001035 drying Methods 0.000 abstract description 4
- 231100000889 vertigo Toxicity 0.000 abstract description 4
- 241000213006 Angelica dahurica Species 0.000 abstract description 3
- 229940126678 chinese medicines Drugs 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 239000000341 volatile oil Substances 0.000 abstract 2
- 241001127714 Amomum Species 0.000 abstract 1
- 241000132012 Atractylodes Species 0.000 abstract 1
- 240000000425 Chaenomeles speciosa Species 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 241000305492 Gastrodia Species 0.000 abstract 1
- 244000047734 Paederia foetida Species 0.000 abstract 1
- 235000019116 Paederia foetida Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 240000003109 Persicaria chinensis Species 0.000 abstract 1
- 241001522129 Pinellia Species 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- 238000004806 packaging method and process Methods 0.000 abstract 1
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- 235000005412 red sage Nutrition 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- -1 tabletting Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 11
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 206010062717 Increased upper airway secretion Diseases 0.000 description 7
- 208000026435 phlegm Diseases 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 241000721047 Danaus plexippus Species 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 206010065559 Cerebral arteriosclerosis Diseases 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000027530 Meniere disease Diseases 0.000 description 1
- 201000006559 Vertebrobasilar insufficiency Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 201000010861 basilar artery insufficiency Diseases 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 201000005851 intracranial arteriosclerosis Diseases 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 230000004206 stomach function Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
A formula of a dizzy-eliminating and dizziness-stopping tablet and a production process thereof are as follows: the prescription comprises Chinese knotweed, paederia scandens, ginger processed pinellia tuber, largehead atractylodes rhizome, tall gastrodia tuber, red sage root, Chinese angelica, white paeony root, Indian buead, common floweringquince fruit, immature bitter orange, villous amomum fruit, grassleaf sweelflag rhizome and dahurian angelica root. The production process is that fourteen Chinese medicines in the formula are divided into three groups, and volatile oil is extracted by distillation respectively; decocting with water to obtain extract; pulverizing the raw materials into fine powder, adding into the extract, mixing, granulating, drying, grading, adding volatile oil, tabletting, coating, drying with silica gel, packaging, inspecting, and warehousing. The invention has unique formula and advanced process, and is a specific Chinese medicament for treating vertigo.
Description
The invention belongs to the technical field of Chinese medicine three kind new medicines.
At present in the world, western patent medicine is various, but be used for the treatment of vertigo in, western patent medicine seldom, have the medicine of special efficacy rare especially to vertigo.Fainting-relieving tablet is the new Chinese medicine of making through proved recipe through a kind of specially good effect that is used for the treatment of dizziness of the tcm clinical practice research of two more than ten years, invention.
The fainting-relieving slice prescription is formed:
Herb Polygoni Chinensis's 400 grams, fevervine 100 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 50 grams, the Rhizoma Atractylodis Macrocephalae 50 grams, Rhizoma Gastrodiae 50 grams, Radix Salviae Miltiorrhizae 100 grams, Radix Angelicae Sinensis 25 grams, the Radix Paeoniae Alba 40 grams, Poria 50 grams, art melon 40 grams, Fructus Aurantii Immaturus 25 grams, Fructus Amomi 5 grams, Rhizoma Acori Graminei 50 grams, the Radix Angelicae Dahuricae 15 grams.
Each medicine total amount of filling a prescription is 1000 grams, makes 1000 of coated tablets altogether, every weight of plain sheet 0.35 gram, and every is equivalent to contain crude drug in whole 1 gram.We are made up of 14 flavor Chinese medicines, just in the Herb Polygoni Chinensis have dampness removing and reduce phlegm, the effect of regulating the liver and spleen is used for the treatment of dizzyly, effect is good, particularly under the situation of reusing, more can bring into play its speciality.Fevervine has dehumidifying and reduces phlegm, the effect that spleen invigorating is invigorated blood circulation, and therefore kind the dizzy of stagnation of turbid phlegm in middle-JIAO of controlling be listed as monarch drug with the Herb Polygoni Chinensis.
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) drying dampness to eliminate phlegm in the side, stopping nausea and vomiting by lowering the adverse flow of QI, Rhizoma Atractylodis Macrocephalae the spleen strengthening and damp drying, Jiao's retardance in the row strengthens the fortuneization function, the Rhizoma Gastrodiae suppressing the hyperactive liver to relieve the wind syndrome, Radix Salviae Miltiorrhizae is invigorated blood circulation, and the same usefulness of this four Chinese medicine and monarch drug can strengthen the effect of the dizzy card of treatment, so be ministerial drug.
Chinese angelica blood supplementing is invigorated blood circulation in the side, is the gas medicine in the blood; Radix Paeoniae Alba regulating nutrient QI and blood is the blood medicine in the blood.Two medicines share, tonify without causing stagnation, nutrient blood is in harmonious proportion, also can take into account treatment because of blood deficiency cause dizzy.The Poria invigorating spleen to remove dampness, the removing dampness of Fructus Chaenomelis stomach function regulating also has the effect of suppressing the hyperactive liver concurrently, Fructus Aurantii Immaturus activating QI to eliminate phlegm, normalizing the stomach by guiding QI downward, Fructus Amomi invigorating the spleen and regulating the stomach, the turbid damp of resistance in can changing.Rhizoma Acori Graminei, the Radix Angelicae Dahuricae, its gas fragrance, the wind that looses that can dehumidify, dissolving turbidity for resucitation.This eight flavors medicine both can assist monarch drug to treat dizzy card, can remove some assorted cards of holding concurrently again, was adjuvant drug therefore.Full side does not need the medicine of guiding drug and coordinating the actions of various ingredients in a prescription, does not therefore have messenger drug in the side.These monarch's side two ministers four are called prescription with ingredients even in number.
Function with cure mainly: spleen invigorating dehumidifying, the blood stasis dispelling suppressing the hyperactive liver is used for the treatment of stagnation of turbid phlegm in middle-JIAO type dizzy (comprise aural vertigo, cerebral arteriosclerosis vertigo and basilar artery insufficiency are dizzy).
Usage and consumption: oral, every day 3 times, each 5, boiled water takes.
Advantage of the present invention:
The fainting-relieving slice prescription is reasonable, and technology is advanced stable, makes meticulously, and the mass production processes maturation is ratified through Ministry of Public Health at present, is carrying out the second stage of clinical research work.
Fainting-relieving tablet has the spleen invigorating dehumidifying, and blood stasis dispelling suppressing the hyperactive liver function is the specific medicament of treatment stagnation of turbid phlegm in middle-JIAO type dizziness.Treatment to dizziness has important breakthrough.
During this Chinese medicine three kind new medicines have solved, doctor trained in Western medicine and treat a big difficult problem of dizziness both at home and abroad, will inevitably be subjected to home and abroad doctor and dizziness patient's attention after the operation and like, so it will demonstrate great economic benefit and social benefit.
The production process of fainting-relieving tablet:
With the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Fructus Aurantii Immaturus, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) five kinds of Chinese medicine clean, chopping, extract volatile component with steam distillation, collects stand-byly, aqueous solution device is in addition preserved, medicinal residues keep for decocting usefulness.
Herb Polygoni Chinensis, fevervine, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Chaenomelis five kinds of Chinese medicine are cleaned, shredded, merge, decoct with water three times with above-mentioned medicinal residues.1.5 hours for the first time, second and third time each 1 hour.Add for the first time the water of 8 times of amounts, second and third time respectively adds the water of 6 times of amounts.Each time decoction liquor leaves standstill 15 hours leaching supernatant, and it is 1.35-1.38 (50 degrees centigrade) thick paste that merging is condensed into relative density.
With starch-containing more, less valuable medicinal Rhizoma Gastrodiae, Poria, Fructus Amomi, the Radix Angelicae Dahuricae of consumption cleaned, and oven dry is pulverized, and sieve (120 order), mixing sterilization back adds in the thick paste.
Thick paste is mixed with above-mentioned medicated powder, and the ethanol that adds supplementary product starch, dextrin and 80% is an amount of, and mixing is granulated with 16 mesh sieves.At temperature 60-70 degree centigrade, vacuum 0.080MPa dry about 7 hours down gets final product to moisture≤6%.
After the granule of the waiting cooling, spray adds collected volatile ingredient and 0.3% magnesium stearate, mixing, and with 14 mesh sieve granulate, tabletting (sheet weighs 0.359), sugar coating is promptly.
Through new patent searching, retrieve following pertinent literature:
1, No. 33, medicine " Yuntongling " for treating dizziness and headache CN1090771A10 volume
2, No. 25, herb medicine tablet for curing dizziness and deaf disease CN1103795A11 volume
3, No. 31, the dizzy Dingxuan medicine CN1105876A11 volume of radical cure
From the pertinent literature that detects, do not find the prescription and the identical patent documentation of production technology that are adopted with this project.
Accompanying drawing is a process chart
Claims (2)
1, a kind of prescription of fainting-relieving tablet and production technology thereof is characterized in that: prescription is made up of Herb Polygoni Chinensis's 400 grams, fevervine 100, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 50 grams, the Rhizoma Atractylodis Macrocephalae 50 grams, Rhizoma Gastrodiae 50 grams, Radix Salviae Miltiorrhizae 100 grams, Radix Angelicae Sinensis 25 grams, the Radix Paeoniae Alba 40 grams, Poria 50 grams, Fructus Chaenomelis 40 grams, Fructus Aurantii Immaturus 25 grams, Fructus Amomi 5 grams, Rhizoma Acori Graminei 50 grams, the Radix Angelicae Dahuricae 15 grams.
2,, it is characterized in that its production technology is according to the prescription and the production technology thereof of the described fainting-relieving tablet of claim 1:
With the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Rhizoma Acori Graminei, Fructus Aurantii Immaturus, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) five kinds of Chinese medicine clean, chopping, extract volatile ingredient with steam distillation, collects stand-byly, aqueous solution device is in addition preserved, medicinal residues keep for decocting usefulness.
Herb Polygoni Chinensis, fevervine, Radix Salviae Miltiorrhizae, the Radix Paeoniae Alba, Fructus Chaenomelis five kinds of Chinese medicine are cleaned, shredded, merge, decoct with water three times with above-mentioned medicinal residues.1.5 hours for the first time, second and third time each 1 hour.Add for the first time the water of 8 times of amounts, second and third time respectively adds the water of 6 times of amounts.Each time decoction liquor leaves standstill 15 hours leaching supernatant, and it is 1.35-138 (50 degrees centigrade) thick paste that merging is condensed into relative density.
With starch-containing more, less valuable medicinal Rhizoma Gastrodiae, Poria, Fructus Amomi, the Radix Angelicae Dahuricae of consumption cleaned, and oven dry is pulverized, and sieve (120 order), mixing sterilization back adds in the thick paste.
Thick paste is mixed with above-mentioned medicated powder, and the ethanol that adds supplementary product starch, dextrin and 80% is an amount of, and mixing is granulated with 16 mesh sieves.At temperature 60-70 degree centigrade, vacuum 0.080MPa dry about 7 hours down gets final product to water content≤6%.
After the granule of the waiting cooling, spray adds collected volatile ingredient and 0.3% magnesium stearate, mixing, and with 14 mesh sieve granulate, tabletting (the heavy 0.35g of sheet), sugar coating is promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95119066A CN1059569C (en) | 1995-12-13 | 1995-12-13 | Dizzy-eliminating and dizziness-stopping tablet and its production process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95119066A CN1059569C (en) | 1995-12-13 | 1995-12-13 | Dizzy-eliminating and dizziness-stopping tablet and its production process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1140078A true CN1140078A (en) | 1997-01-15 |
| CN1059569C CN1059569C (en) | 2000-12-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95119066A Expired - Fee Related CN1059569C (en) | 1995-12-13 | 1995-12-13 | Dizzy-eliminating and dizziness-stopping tablet and its production process |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1059569C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087952C (en) * | 1999-12-24 | 2002-07-24 | 贡道仁 | Method for producing medicine for curing vertigo |
| CN101966299A (en) * | 2010-10-26 | 2011-02-09 | 左权县蓝天中药科技开发有限公司 | Medicament for treating wind-caused dizziness |
| CN101264143B (en) * | 2008-04-15 | 2011-09-14 | 贵州金宇药业有限公司 | Chinese medicine preparation for treating gynecologic inflammation and preparation thereof |
| CN104162021A (en) * | 2014-07-24 | 2014-11-26 | 杜业坚 | Powder for treating carsickness and preparation method thereof |
| CN104645075A (en) * | 2013-11-22 | 2015-05-27 | 童绥君 | Pharmaceutical composition for treating dizziness |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1105876A (en) * | 1994-01-31 | 1995-08-02 | 贺易庭 | "Dingxuan" medicine for radically treating dizziness disease |
-
1995
- 1995-12-13 CN CN95119066A patent/CN1059569C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087952C (en) * | 1999-12-24 | 2002-07-24 | 贡道仁 | Method for producing medicine for curing vertigo |
| CN101264143B (en) * | 2008-04-15 | 2011-09-14 | 贵州金宇药业有限公司 | Chinese medicine preparation for treating gynecologic inflammation and preparation thereof |
| CN101966299A (en) * | 2010-10-26 | 2011-02-09 | 左权县蓝天中药科技开发有限公司 | Medicament for treating wind-caused dizziness |
| CN104645075A (en) * | 2013-11-22 | 2015-05-27 | 童绥君 | Pharmaceutical composition for treating dizziness |
| CN104162021A (en) * | 2014-07-24 | 2014-11-26 | 杜业坚 | Powder for treating carsickness and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN1059569C (en) | 2000-12-20 |
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