CN113994194B - 生物分析装置和系统 - Google Patents

生物分析装置和系统

Info

Publication number
CN113994194B
CN113994194B CN202080044632.1A CN202080044632A CN113994194B CN 113994194 B CN113994194 B CN 113994194B CN 202080044632 A CN202080044632 A CN 202080044632A CN 113994194 B CN113994194 B CN 113994194B
Authority
CN
China
Prior art keywords
excitation
emission
sample
excitation light
analysis system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202080044632.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN113994194A (zh
Inventor
陈明松
张智伟
罗戊耿
符文玉
巫冠文
N·莱克勒克
R·柯埃林奈尔
T·富克斯
S·布瑞特费勒德尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Technology Holdings Pte Ltd
Life Technologies Corp
Original Assignee
Life Technology Holdings Pte Ltd
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technology Holdings Pte Ltd, Life Technologies Corp filed Critical Life Technology Holdings Pte Ltd
Publication of CN113994194A publication Critical patent/CN113994194A/zh
Application granted granted Critical
Publication of CN113994194B publication Critical patent/CN113994194B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6478—Special lenses

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202080044632.1A 2019-06-19 2020-06-18 生物分析装置和系统 Active CN113994194B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962863774P 2019-06-19 2019-06-19
US62/863,774 2019-06-19
PCT/US2020/038352 WO2020257399A1 (en) 2019-06-19 2020-06-18 Biological analysis devices and systems

Publications (2)

Publication Number Publication Date
CN113994194A CN113994194A (zh) 2022-01-28
CN113994194B true CN113994194B (zh) 2026-03-24

Family

ID=71579657

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080044632.1A Active CN113994194B (zh) 2019-06-19 2020-06-18 生物分析装置和系统

Country Status (6)

Country Link
US (3) US11237108B2 (https=)
EP (1) EP3987274A1 (https=)
JP (2) JP7553487B2 (https=)
KR (1) KR20220024561A (https=)
CN (1) CN113994194B (https=)
WO (1) WO2020257399A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10473591B2 (en) * 2017-05-01 2019-11-12 Wyatt Technology Corporation High throughput method and apparatus for measuring multiple optical properties of a liquid sample
CN113994194B (zh) * 2019-06-19 2026-03-24 生命科技控股私人有限公司 生物分析装置和系统
CN114397285A (zh) * 2022-03-02 2022-04-26 北京卓立汉光分析仪器有限公司 多样品光致发光测试装置
WO2025117598A1 (en) * 2023-11-28 2025-06-05 Life Technologies Holdings Pte Ltd Illumination system for a bio-analytical instrument

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101995398A (zh) * 2009-08-12 2011-03-30 索尼公司 光检测装置
JP2017189175A (ja) * 2012-07-31 2017-10-19 ジェン−プローブ・インコーポレーテッド 自動インキュベーションのためのシステム、方法、および装置

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JP2000346828A (ja) * 1999-06-02 2000-12-15 Hitachi Ltd 電気泳動装置
US7217573B1 (en) 1999-10-05 2007-05-15 Hitachi, Ltd. Method of inspecting a DNA chip
US6563581B1 (en) 2000-07-14 2003-05-13 Applera Corporation Scanning system and method for scanning a plurality of samples
DE10127611C2 (de) * 2001-06-07 2003-08-07 Jena Optronik Gmbh Anordnung zum Anregen und Auslesen der Fluoreszenzstrahlung eines Probenträgers mit einer Vielzahl von Einzelproben
ATE412170T1 (de) * 2004-12-17 2008-11-15 Koninkl Philips Electronics Nv Mehrpunktuntersuchungsgerät
US20070057211A1 (en) * 2005-05-25 2007-03-15 Karsten Bahlman Multifocal imaging systems and method
JP2007064749A (ja) 2005-08-30 2007-03-15 Jasco Corp 試料用セル、及びセルホルダ
US7329860B2 (en) * 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
US8686376B2 (en) 2008-06-24 2014-04-01 Koninklijke Philips N.V. Microarray characterization system and method
WO2010039975A1 (en) 2008-10-03 2010-04-08 Nanodrop Technologies Llc Dual sample mode spectrophotometer
US10101274B2 (en) * 2012-12-05 2018-10-16 Genepoc Inc. Optical interrogation device
AU2015326540B2 (en) 2014-09-29 2020-11-26 Bd Kiestra B.V. Apparatus for optical inspection of small volumes of liquid sample and cuvettes therefor
EP3312593A1 (de) * 2016-10-20 2018-04-25 Hain Lifescience GmbH Verfahren und vorrichtung zur optischen anregung einer mehrzahl von analyten in einem array von reaktionsgefässen und zur erfassung von fluoreszenzlicht aus dem analyten
CN113994194B (zh) * 2019-06-19 2026-03-24 生命科技控股私人有限公司 生物分析装置和系统
CN112683869B (zh) * 2020-12-25 2023-03-14 中国科学院苏州生物医学工程技术研究所 一种荧光定量检测方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101995398A (zh) * 2009-08-12 2011-03-30 索尼公司 光检测装置
JP2017189175A (ja) * 2012-07-31 2017-10-19 ジェン−プローブ・インコーポレーテッド 自動インキュベーションのためのシステム、方法、および装置

Also Published As

Publication number Publication date
US11680905B2 (en) 2023-06-20
US20230417676A1 (en) 2023-12-28
KR20220024561A (ko) 2022-03-03
JP7553487B2 (ja) 2024-09-18
JP2022536804A (ja) 2022-08-18
US11237108B2 (en) 2022-02-01
US20220205915A1 (en) 2022-06-30
JP2024180392A (ja) 2024-12-26
WO2020257399A1 (en) 2020-12-24
EP3987274A1 (en) 2022-04-27
CN113994194A (zh) 2022-01-28
US20200400569A1 (en) 2020-12-24
US12140544B2 (en) 2024-11-12

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