CN113943373B - 一种β冠状病毒多聚体抗原、其制备方法和应用 - Google Patents

一种β冠状病毒多聚体抗原、其制备方法和应用 Download PDF

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CN113943373B
CN113943373B CN202011165603.9A CN202011165603A CN113943373B CN 113943373 B CN113943373 B CN 113943373B CN 202011165603 A CN202011165603 A CN 202011165603A CN 113943373 B CN113943373 B CN 113943373B
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CN113943373A (zh
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高福
戴连攀
徐坤
韩雨旋
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Institute of Microbiology of CAS
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CN202011165603.9A 2020-10-27 2020-10-27 一种β冠状病毒多聚体抗原、其制备方法和应用 Active CN113943373B (zh)

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Application Number Priority Date Filing Date Title
CN202210965078.1A CN115838433A (zh) 2020-10-27 2020-10-27 一种β冠状病毒多聚体抗原、其制备方法和应用
CN202011165603.9A CN113943373B (zh) 2020-10-27 2020-10-27 一种β冠状病毒多聚体抗原、其制备方法和应用
PCT/CN2021/126639 WO2022089471A1 (fr) 2020-10-27 2021-10-27 ANTIGÈNE MULTIMÈRE DE β-CORONAVIRUS, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION

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CN113817029B (zh) * 2021-03-31 2022-09-23 国药中生生物技术研究院有限公司 一种新型冠状病毒s-rbd三聚体蛋白疫苗、其制备方法和应用
CN115975042B (zh) * 2021-08-26 2023-12-29 中国科学院微生物研究所 一种β冠状病毒异源多聚体抗原、其制备方法和应用
CN115124626A (zh) * 2022-05-11 2022-09-30 中国科学院微生物研究所 串联式杂合三聚体新冠疫苗
CN114989308B (zh) * 2022-05-12 2023-04-04 中国科学院微生物研究所 新冠病毒嵌合核酸疫苗及其用途
CN115678906B (zh) * 2022-05-12 2023-09-19 中国科学院微生物研究所 经优化的新冠病毒嵌合核酸疫苗及其用途
CN114751992B (zh) * 2022-05-25 2024-05-31 中国科学院微生物研究所 一种冠状病毒的通用疫苗及其应用
CN117582492A (zh) * 2022-08-12 2024-02-23 上海市公共卫生临床中心 重组多价疫苗

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CN111217919A (zh) * 2020-03-04 2020-06-02 中山大学 一种基于火球菌铁蛋白的新型冠状病毒s蛋白双区域亚单位纳米疫苗
CN111592602A (zh) * 2020-02-10 2020-08-28 中国科学院微生物研究所 一种β冠状病毒抗原、其制备方法和应用

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EP3046579A1 (fr) * 2013-09-19 2016-07-27 Novavax, Inc. Compositions de coronavirus du syndrome respiratoire du moyen-orient (mers-cov) immunogènes et procédés
US10676511B2 (en) * 2015-09-17 2020-06-09 Ramot At Tel-Aviv University Ltd. Coronaviruses epitope-based vaccines
CN106928326B (zh) * 2015-12-31 2019-12-24 中国科学院微生物研究所 一种基于二聚化的受体结合区亚单位的冠状病毒疫苗
CN112048005B (zh) * 2020-09-04 2022-09-09 江苏省中国科学院植物研究所 新型冠状病毒s蛋白片段多倍体及其制备方法、检测试剂盒、疫苗及药物
CN113461787A (zh) * 2021-04-28 2021-10-01 国药中生生物技术研究院有限公司 一种重组新型冠状病毒s-rbd三聚体蛋白、其制备方法和应用
CN113861278B (zh) * 2021-06-18 2022-08-05 国药中生生物技术研究院有限公司 一种产生广谱交叉中和活性的重组新型冠状病毒rbd三聚体蛋白疫苗、其制备方法和应用
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CN111217919A (zh) * 2020-03-04 2020-06-02 中山大学 一种基于火球菌铁蛋白的新型冠状病毒s蛋白双区域亚单位纳米疫苗

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