CN113908253A - 环状鞘脂激活蛋白原肽及其用途 - Google Patents

环状鞘脂激活蛋白原肽及其用途 Download PDF

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Publication number
CN113908253A
CN113908253A CN202111206782.0A CN202111206782A CN113908253A CN 113908253 A CN113908253 A CN 113908253A CN 202111206782 A CN202111206782 A CN 202111206782A CN 113908253 A CN113908253 A CN 113908253A
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China
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peptide
cyclic
leu
pro
seq
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CN202111206782.0A
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English (en)
Chinese (zh)
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伦道夫·S·瓦特尼克
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Boston Children's Hospital
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Boston Children's Hospital
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN202111206782.0A 2014-03-26 2015-03-26 环状鞘脂激活蛋白原肽及其用途 Pending CN113908253A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461970853P 2014-03-26 2014-03-26
US61/970,853 2014-03-26
CN201580021626.3A CN106659764B (zh) 2014-03-26 2015-03-26 环状鞘脂激活蛋白原肽及其用途

Related Parent Applications (1)

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CN201580021626.3A Division CN106659764B (zh) 2014-03-26 2015-03-26 环状鞘脂激活蛋白原肽及其用途

Publications (1)

Publication Number Publication Date
CN113908253A true CN113908253A (zh) 2022-01-11

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CN202111206782.0A Pending CN113908253A (zh) 2014-03-26 2015-03-26 环状鞘脂激活蛋白原肽及其用途
CN201580021626.3A Active CN106659764B (zh) 2014-03-26 2015-03-26 环状鞘脂激活蛋白原肽及其用途

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Country Link
US (5) US10646541B2 (enExample)
EP (2) EP3122369B1 (enExample)
JP (4) JP6727129B2 (enExample)
CN (2) CN113908253A (enExample)
AU (4) AU2015235978B2 (enExample)
WO (1) WO2015148801A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3127549B1 (en) 2007-06-22 2019-12-18 Children's Medical Center Corporation Methods and uses thereof of a fragment of saposin a
US10646541B2 (en) * 2014-03-26 2020-05-12 Children's Medical Center Corporation Cyclic prosaposin peptides and uses thereof
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
EP4449125A4 (en) * 2021-12-17 2026-01-28 Vigeo Therapeutics Inc CANCER TREATMENT METHODS AND COMPOSITIONS

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CA2860226A1 (en) * 2011-12-22 2013-06-27 Randolph S. Watnick Saposin-a derived peptides and uses thereof
CN105358708A (zh) * 2013-03-14 2016-02-24 儿童医学中心公司 Cd36鉴定癌症对象以用于治疗的用途

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JP2025010144A (ja) 2025-01-20
JP2017512799A (ja) 2017-05-25
WO2015148801A1 (en) 2015-10-01
EP4154901A1 (en) 2023-03-29
AU2015235978A1 (en) 2016-10-20
AU2021203082A1 (en) 2021-06-10
EP3122369B1 (en) 2022-08-31
US20200246419A1 (en) 2020-08-06
US11191805B2 (en) 2021-12-07
US20260091083A1 (en) 2026-04-02
AU2015235978B2 (en) 2019-08-08
AU2023204392A1 (en) 2023-08-03
CA2943802A1 (en) 2015-10-01
US10646541B2 (en) 2020-05-12
JP2023053978A (ja) 2023-04-13
US20240139279A1 (en) 2024-05-02
CN106659764B (zh) 2021-11-02
EP3122369A4 (en) 2017-09-27
US11654178B2 (en) 2023-05-23
EP3122369A1 (en) 2017-02-01
JP7284726B2 (ja) 2023-05-31
US20220152146A1 (en) 2022-05-19
CN106659764A (zh) 2017-05-10
US20170173109A1 (en) 2017-06-22
JP6727129B2 (ja) 2020-07-22
AU2019204952A1 (en) 2019-07-25
EP4154901B1 (en) 2026-07-29
JP2020117504A (ja) 2020-08-06

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Application publication date: 20220111