JP6727129B2 - 環状プロサポシンペプチドおよびその使用 - Google Patents

環状プロサポシンペプチドおよびその使用 Download PDF

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Publication number
JP6727129B2
JP6727129B2 JP2016559300A JP2016559300A JP6727129B2 JP 6727129 B2 JP6727129 B2 JP 6727129B2 JP 2016559300 A JP2016559300 A JP 2016559300A JP 2016559300 A JP2016559300 A JP 2016559300A JP 6727129 B2 JP6727129 B2 JP 6727129B2
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Prior art keywords
peptide
cyclic
seq
cancer
peptides
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Japanese (ja)
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JP2017512799A5 (enExample
JP2017512799A (ja
Inventor
ワトニック，ランドルフ，エス．
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Boston Children's Hospital
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Boston Children's Hospital
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2016559300A 2014-03-26 2015-03-26 環状プロサポシンペプチドおよびその使用 Active JP6727129B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461970853P 2014-03-26 2014-03-26
US61/970,853 2014-03-26
PCT/US2015/022745 WO2015148801A1 (en) 2014-03-26 2015-03-26 Cyclic prosaposin peptides and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020029398A Division JP7284726B2 (ja) 2014-03-26 2020-02-25 環状プロサポシンペプチドおよびその使用

Publications (3)

Publication Number Publication Date
JP2017512799A JP2017512799A (ja) 2017-05-25
JP2017512799A5 JP2017512799A5 (enExample) 2018-05-24
JP6727129B2 true JP6727129B2 (ja) 2020-07-22

Family

ID=54196396

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016559300A Active JP6727129B2 (ja) 2014-03-26 2015-03-26 環状プロサポシンペプチドおよびその使用
JP2020029398A Active JP7284726B2 (ja) 2014-03-26 2020-02-25 環状プロサポシンペプチドおよびその使用
JP2023010162A Pending JP2023053978A (ja) 2014-03-26 2023-01-26 環状プロサポシンペプチドおよびその使用
JP2024170459A Pending JP2025010144A (ja) 2014-03-26 2024-09-30 環状プロサポシンペプチドおよびその使用

Family Applications After (3)

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JP2020029398A Active JP7284726B2 (ja) 2014-03-26 2020-02-25 環状プロサポシンペプチドおよびその使用
JP2023010162A Pending JP2023053978A (ja) 2014-03-26 2023-01-26 環状プロサポシンペプチドおよびその使用
JP2024170459A Pending JP2025010144A (ja) 2014-03-26 2024-09-30 環状プロサポシンペプチドおよびその使用

Country Status (6)

Country Link
US (5) US10646541B2 (enExample)
EP (2) EP3122369B1 (enExample)
JP (4) JP6727129B2 (enExample)
CN (2) CN113908253A (enExample)
AU (4) AU2015235978B2 (enExample)
WO (1) WO2015148801A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020117504A (ja) * 2014-03-26 2020-08-06 ザ チルドレンズ メディカル センター コーポレーション 環状プロサポシンペプチドおよびその使用
US12117448B2 (en) 2007-06-22 2024-10-15 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
EP4449125A4 (en) * 2021-12-17 2026-01-28 Vigeo Therapeutics Inc CANCER TREATMENT METHODS AND COMPOSITIONS

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12117448B2 (en) 2007-06-22 2024-10-15 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof
JP2020117504A (ja) * 2014-03-26 2020-08-06 ザ チルドレンズ メディカル センター コーポレーション 環状プロサポシンペプチドおよびその使用
JP7284726B2 (ja) 2014-03-26 2023-05-31 ザ チルドレンズ メディカル センター コーポレーション 環状プロサポシンペプチドおよびその使用

Also Published As

Publication number Publication date
JP2025010144A (ja) 2025-01-20
JP2017512799A (ja) 2017-05-25
WO2015148801A1 (en) 2015-10-01
EP4154901A1 (en) 2023-03-29
AU2015235978A1 (en) 2016-10-20
AU2021203082A1 (en) 2021-06-10
EP3122369B1 (en) 2022-08-31
US20200246419A1 (en) 2020-08-06
US11191805B2 (en) 2021-12-07
US20260091083A1 (en) 2026-04-02
AU2015235978B2 (en) 2019-08-08
AU2023204392A1 (en) 2023-08-03
CA2943802A1 (en) 2015-10-01
US10646541B2 (en) 2020-05-12
JP2023053978A (ja) 2023-04-13
US20240139279A1 (en) 2024-05-02
CN106659764B (zh) 2021-11-02
EP3122369A4 (en) 2017-09-27
US11654178B2 (en) 2023-05-23
EP3122369A1 (en) 2017-02-01
JP7284726B2 (ja) 2023-05-31
US20220152146A1 (en) 2022-05-19
CN106659764A (zh) 2017-05-10
US20170173109A1 (en) 2017-06-22
AU2019204952A1 (en) 2019-07-25
CN113908253A (zh) 2022-01-11
EP4154901B1 (en) 2026-07-29
JP2020117504A (ja) 2020-08-06

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