CN113908156A - 用于治疗非精神分裂症患者中的阴性症状的组合物和方法 - Google Patents

用于治疗非精神分裂症患者中的阴性症状的组合物和方法 Download PDF

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Publication number
CN113908156A
CN113908156A CN202111014298.8A CN202111014298A CN113908156A CN 113908156 A CN113908156 A CN 113908156A CN 202111014298 A CN202111014298 A CN 202111014298A CN 113908156 A CN113908156 A CN 113908156A
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compound
subject
weeks
disorder
composition
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Pending
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CN202111014298.8A
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English (en)
Chinese (zh)
Inventor
R·鲁斯林格
M·达维德森
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Tanabe Pharma Corp
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Mitsubishi Tanabe Pharma Corp
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Publication of CN113908156A publication Critical patent/CN113908156A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN202111014298.8A 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法 Pending CN113908156A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662341590P 2016-05-25 2016-05-25
US62/341590 2016-05-25
CN201780045461.2A CN109689055A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法

Related Parent Applications (1)

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CN201780045461.2A Division CN109689055A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法

Publications (1)

Publication Number Publication Date
CN113908156A true CN113908156A (zh) 2022-01-11

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Family Applications (3)

Application Number Title Priority Date Filing Date
CN202111014298.8A Pending CN113908156A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法
CN201780045461.2A Pending CN109689055A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法
CN202111014262.XA Pending CN113694065A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201780045461.2A Pending CN109689055A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法
CN202111014262.XA Pending CN113694065A (zh) 2016-05-25 2017-05-23 用于治疗非精神分裂症患者中的阴性症状的组合物和方法

Country Status (9)

Country Link
US (2) US20190216793A1 (enExample)
EP (1) EP3463356A1 (enExample)
JP (3) JP2019516756A (enExample)
KR (2) KR20240005110A (enExample)
CN (3) CN113908156A (enExample)
PH (1) PH12018502445A1 (enExample)
SG (2) SG10202011470UA (enExample)
TW (2) TWI820001B (enExample)
WO (1) WO2017205393A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015355226B2 (en) 2014-12-02 2020-04-02 Minerva Neurosciences, Inc. Compositions comprising 2-((1-(2(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one for treating schizophrenia
IL319156A (en) 2017-06-21 2025-04-01 Minerva Neurosciences Inc Controlled-release oral dosage forms are resistant to gastric acid.
US11083723B2 (en) * 2018-08-21 2021-08-10 Minerva Neurosciences, Inc. Use of roluperidone to treat negative symptoms and disorders, increase neuroplasticity, and promote neuroprotection
TWI879755B (zh) * 2020-02-20 2025-04-11 日商田邊三菱製藥股份有限公司 魯哌啶酮用於治療負性症狀及疾病、增加神經可塑性及促進神經保護的用途
KR102360137B1 (ko) * 2020-03-25 2022-02-08 주식회사 케이티앤지 카트리지 및 이를 포함하는 에어로졸 생성 장치
CN116847843A (zh) * 2021-02-09 2023-10-03 泽农医药公司 用于治疗快感缺乏的电压门控的钾通道开放剂
US20240212824A1 (en) * 2022-12-21 2024-06-27 Woebot Labs, Inc. Administering a digital therapeutic using a device interface to treat anxiety or depression

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN101273982A (zh) * 2007-03-30 2008-10-01 田边三菱制药株式会社 预防和/或治疗抑郁症的药物
CN101378752A (zh) * 2006-02-07 2009-03-04 田边三菱制药株式会社 4-酰氨基吡啶衍生物介导的神经发生
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200616608A (en) * 2004-07-09 2006-06-01 Forest Laboratories Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients
RU2746871C2 (ru) * 2010-07-20 2021-04-21 Сиренейк Фармасьютикалз Инк. Способы применения производных циклического амида для лечения опосредуемых сигма-рецепторами расстройств
US8937900B2 (en) * 2010-07-20 2015-01-20 Qualcomm Incorporated Enhancing pilot channel transmission in TD-SCDMA multicarrier systems using secondary carrier frequencies
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
JP6531093B2 (ja) * 2014-05-16 2019-06-12 武田薬品工業株式会社 含窒素複素環化合物
AU2015355226B2 (en) * 2014-12-02 2020-04-02 Minerva Neurosciences, Inc. Compositions comprising 2-((1-(2(4-Fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one for treating schizophrenia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN101378752A (zh) * 2006-02-07 2009-03-04 田边三菱制药株式会社 4-酰氨基吡啶衍生物介导的神经发生
CN101273982A (zh) * 2007-03-30 2008-10-01 田边三菱制药株式会社 预防和/或治疗抑郁症的药物
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

Also Published As

Publication number Publication date
JP2025000921A (ja) 2025-01-07
JP2022188185A (ja) 2022-12-20
JP2019516756A (ja) 2019-06-20
TW201808288A (zh) 2018-03-16
US20230190726A1 (en) 2023-06-22
CN113694065A (zh) 2021-11-26
SG10202011470UA (en) 2021-01-28
PH12018502445A1 (en) 2019-09-09
CN109689055A (zh) 2019-04-26
KR20190013846A (ko) 2019-02-11
KR20240005110A (ko) 2024-01-11
TWI851224B (zh) 2024-08-01
TW202335672A (zh) 2023-09-16
WO2017205393A1 (en) 2017-11-30
EP3463356A1 (en) 2019-04-10
TWI820001B (zh) 2023-11-01
US20190216793A1 (en) 2019-07-18
SG11201810358YA (en) 2018-12-28

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