TWI820001B - 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 - Google Patents

醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 Download PDF

Info

Publication number
TWI820001B
TWI820001B TW106117023A TW106117023A TWI820001B TW I820001 B TWI820001 B TW I820001B TW 106117023 A TW106117023 A TW 106117023A TW 106117023 A TW106117023 A TW 106117023A TW I820001 B TWI820001 B TW I820001B
Authority
TW
Taiwan
Prior art keywords
compound
weeks
subject
therapeutically effective
item
Prior art date
Application number
TW106117023A
Other languages
English (en)
Chinese (zh)
Other versions
TW201808288A (zh
Inventor
雷米 盧思林格
麥可 大衛森
Original Assignee
日商田邊三菱製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日商田邊三菱製藥股份有限公司 filed Critical 日商田邊三菱製藥股份有限公司
Publication of TW201808288A publication Critical patent/TW201808288A/zh
Application granted granted Critical
Publication of TWI820001B publication Critical patent/TWI820001B/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW106117023A 2016-05-25 2017-05-23 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 TWI820001B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662341590P 2016-05-25 2016-05-25
US62/341,590 2016-05-25

Publications (2)

Publication Number Publication Date
TW201808288A TW201808288A (zh) 2018-03-16
TWI820001B true TWI820001B (zh) 2023-11-01

Family

ID=58794265

Family Applications (2)

Application Number Title Priority Date Filing Date
TW106117023A TWI820001B (zh) 2016-05-25 2017-05-23 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途
TW112118953A TWI851224B (zh) 2016-05-25 2017-05-23 非思覺失調症病患之負性症狀治療用醫藥組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW112118953A TWI851224B (zh) 2016-05-25 2017-05-23 非思覺失調症病患之負性症狀治療用醫藥組成物

Country Status (9)

Country Link
US (2) US20190216793A1 (enExample)
EP (1) EP3463356A1 (enExample)
JP (3) JP2019516756A (enExample)
KR (2) KR20240005110A (enExample)
CN (3) CN113694065A (enExample)
PH (1) PH12018502445A1 (enExample)
SG (2) SG10202011470UA (enExample)
TW (2) TWI820001B (enExample)
WO (1) WO2017205393A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL301320B2 (en) 2014-12-02 2024-11-01 Minerva Neurosciences Inc Compositions comprising 2-((1-(2(4-fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one for treating schizophrenia
JP2020525436A (ja) 2017-06-21 2020-08-27 ミネルバ・ニューロサイエンシズ・インコーポレイテッド 胃耐性制御放出経口剤形
EP3840835A1 (en) * 2018-08-21 2021-06-30 Minerva Neurosciences, Inc. Use of roluperidone to treat negative symptoms and disorders, increase neuroplasticity, and promote neuroprotection
TWI879755B (zh) * 2020-02-20 2025-04-11 日商田邊三菱製藥股份有限公司 魯哌啶酮用於治療負性症狀及疾病、增加神經可塑性及促進神經保護的用途
KR102360137B1 (ko) * 2020-03-25 2022-02-08 주식회사 케이티앤지 카트리지 및 이를 포함하는 에어로졸 생성 장치
TW202245744A (zh) * 2021-02-09 2022-12-01 加拿大商再諾製藥公司 治療失樂症之方法及用途
WO2024138073A1 (en) * 2022-12-21 2024-06-27 Woebot Labs, Inc. Administering a digital therapeutic using a device interface to treat anxiety or depression

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200616608A (en) * 2004-07-09 2006-06-01 Forest Laboratories Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients
KR20080093453A (ko) * 2006-02-07 2008-10-21 미쓰비시 타나베 파마 코퍼레이션 4-아실아미노피리딘 유도체 매개된 신경조직발생
KR20080089279A (ko) * 2007-03-30 2008-10-06 미쓰비시 타나베 파마 코퍼레이션 우울증의 예방 및/또는 치료제
US8937900B2 (en) * 2010-07-20 2015-01-20 Qualcomm Incorporated Enhancing pilot channel transmission in TD-SCDMA multicarrier systems using secondary carrier frequencies
RU2746871C2 (ru) * 2010-07-20 2021-04-21 Сиренейк Фармасьютикалз Инк. Способы применения производных циклического амида для лечения опосредуемых сигма-рецепторами расстройств
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
JP6531093B2 (ja) * 2014-05-16 2019-06-12 武田薬品工業株式会社 含窒素複素環化合物
IL301320B2 (en) * 2014-12-02 2024-11-01 Minerva Neurosciences Inc Compositions comprising 2-((1-(2(4-fluorophenyl)-2-oxoethyl)piperidin-4-yl)methyl)isoindolin-1-one for treating schizophrenia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

Also Published As

Publication number Publication date
CN109689055A (zh) 2019-04-26
TW202335672A (zh) 2023-09-16
SG11201810358YA (en) 2018-12-28
JP2019516756A (ja) 2019-06-20
KR20190013846A (ko) 2019-02-11
JP2025000921A (ja) 2025-01-07
JP2022188185A (ja) 2022-12-20
WO2017205393A1 (en) 2017-11-30
EP3463356A1 (en) 2019-04-10
KR20240005110A (ko) 2024-01-11
TW201808288A (zh) 2018-03-16
SG10202011470UA (en) 2021-01-28
TWI851224B (zh) 2024-08-01
US20230190726A1 (en) 2023-06-22
US20190216793A1 (en) 2019-07-18
CN113694065A (zh) 2021-11-26
PH12018502445A1 (en) 2019-09-09
CN113908156A (zh) 2022-01-11

Similar Documents

Publication Publication Date Title
US11680044B2 (en) Pharmaceutical composition comprising 5-methoxy-n,n-dimethyltryptamine
TWI851224B (zh) 非思覺失調症病患之負性症狀治療用醫藥組成物
CN113993523A (zh) 用赛洛西宾治疗抑郁症和其他各种病症
KR20230170716A (ko) 본태성 진전 치료
US20250000881A1 (en) Treatment of treatment resistant depression with psilocybin
CN120641095A (zh) 精神障碍的治疗
HK1207593A1 (en) Medicament for treating mental and behavioural disorders
JP2022526101A (ja) 重水素化デキストロメトルファン及びキニジンを使用して統合失調症の陰性症状を治療する方法
US20260041667A1 (en) Prescription digital therapeutics
TW201242600A (en) Treatment of cognitive dysfunction in schizophrenia
KR20240122455A (ko) 치료-저항성 우울증의 치료에서 사용하기 위한 실로사이빈 및 보조적 세로토닌 재흡수 저해제
WO2025218751A1 (zh) 一种组合物在制备药物中的应用
JP2026507099A (ja) シロシビン類似体を用いて障害を治療する方法
WO2026068950A1 (en) Pharmaceutical compositions of 5-meo-dmt for use in the treatment of alcohol use disorders
CN118488843A (zh) 用赛洛西宾治疗难治性抑郁症
Zornig the beauty of~ relief.
HK1190945A (en) Use of testosterone and a 5-ht1a agonist in the treatment of sexual dysfunction