TWI820001B - 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 - Google Patents

醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 Download PDF

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TWI820001B
TWI820001B TW106117023A TW106117023A TWI820001B TW I820001 B TWI820001 B TW I820001B TW 106117023 A TW106117023 A TW 106117023A TW 106117023 A TW106117023 A TW 106117023A TW I820001 B TWI820001 B TW I820001B
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therapeutically effective
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TW201808288A (zh
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雷米 盧思林格
麥可 大衛森
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日商田邊三菱製藥股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
TW106117023A 2016-05-25 2017-05-23 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途 TWI820001B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662341590P 2016-05-25 2016-05-25
US62/341,590 2016-05-25

Publications (2)

Publication Number Publication Date
TW201808288A TW201808288A (zh) 2018-03-16
TWI820001B true TWI820001B (zh) 2023-11-01

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TW112118953A TWI851224B (zh) 2016-05-25 2017-05-23 非思覺失調症病患之負性症狀治療用醫藥組成物
TW106117023A TWI820001B (zh) 2016-05-25 2017-05-23 醫藥組成物的用於製造非思覺失調症病患之負性症狀治療劑的用途

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TW112118953A TWI851224B (zh) 2016-05-25 2017-05-23 非思覺失調症病患之負性症狀治療用醫藥組成物

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US (2) US20190216793A1 (enExample)
EP (1) EP3463356A1 (enExample)
JP (3) JP2019516756A (enExample)
KR (2) KR20240005110A (enExample)
CN (3) CN113908156A (enExample)
PH (1) PH12018502445A1 (enExample)
SG (2) SG11201810358YA (enExample)
TW (2) TWI851224B (enExample)
WO (1) WO2017205393A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018501217A (ja) 2014-12-02 2018-01-18 田辺三菱製薬株式会社 統合失調症を治療するための2−((1−(2(4−フルオロフェニル)−2−オキソエチル)ピペリジン−4−イル)メチル)イソインドリン−1−オン
IL271606B2 (en) 2017-06-21 2024-05-01 Minerva Neurosciences Inc Gastro-resistant controlled release oral dosage forms
CA3108882A1 (en) * 2018-08-21 2020-02-27 Minerva Neurosciences, Inc. Use of roluperidone to treat negative symptoms and disorders, increase neuroplasticity, and promote neuroprotection
TWI879755B (zh) * 2020-02-20 2025-04-11 日商田邊三菱製藥股份有限公司 魯哌啶酮用於治療負性症狀及疾病、增加神經可塑性及促進神經保護的用途
KR102360137B1 (ko) * 2020-03-25 2022-02-08 주식회사 케이티앤지 카트리지 및 이를 포함하는 에어로졸 생성 장치
GEAP202416348A (en) * 2021-02-09 2024-01-10 Xenon Pharmaceuticals Inc Methods and uses for treating anhedonia
WO2024138073A1 (en) * 2022-12-21 2024-06-27 Woebot Labs, Inc. Administering a digital therapeutic using a device interface to treat anxiety or depression

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
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TW200616608A (en) * 2004-07-09 2006-06-01 Forest Laboratories Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients
JP2009525979A (ja) * 2006-02-07 2009-07-16 田辺三菱製薬株式会社 4−アシルアミノピリジン誘導体を介した神経新生
CN101273982A (zh) * 2007-03-30 2008-10-01 田边三菱制药株式会社 预防和/或治疗抑郁症的药物
US8937900B2 (en) * 2010-07-20 2015-01-20 Qualcomm Incorporated Enhancing pilot channel transmission in TD-SCDMA multicarrier systems using secondary carrier frequencies
CA3154027A1 (en) * 2010-07-20 2012-01-26 Cyrenaic Pharmaceuticals, Inc. Use of cyclic amide derivatives to treat sigma receptor-mediated disorders
US9737531B2 (en) * 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
JP6531093B2 (ja) * 2014-05-16 2019-06-12 武田薬品工業株式会社 含窒素複素環化合物
JP2018501217A (ja) * 2014-12-02 2018-01-18 田辺三菱製薬株式会社 統合失調症を治療するための2−((1−(2(4−フルオロフェニル)−2−オキソエチル)ピペリジン−4−イル)メチル)イソインドリン−1−オン

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1426405A (zh) * 2000-02-29 2003-06-25 三菱制药株式会社 新型环状酰胺衍生物
CN103220910A (zh) * 2010-07-20 2013-07-24 昔勒尼药品公司 使用环酰胺衍生物治疗精神分裂症的方法

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Publication number Publication date
US20230190726A1 (en) 2023-06-22
US20190216793A1 (en) 2019-07-18
CN109689055A (zh) 2019-04-26
TW201808288A (zh) 2018-03-16
KR20240005110A (ko) 2024-01-11
SG11201810358YA (en) 2018-12-28
TWI851224B (zh) 2024-08-01
SG10202011470UA (en) 2021-01-28
TW202335672A (zh) 2023-09-16
WO2017205393A1 (en) 2017-11-30
CN113694065A (zh) 2021-11-26
CN113908156A (zh) 2022-01-11
JP2025000921A (ja) 2025-01-07
JP2019516756A (ja) 2019-06-20
JP2022188185A (ja) 2022-12-20
EP3463356A1 (en) 2019-04-10
PH12018502445A1 (en) 2019-09-09
KR20190013846A (ko) 2019-02-11

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