CN113907402A - Traditional Chinese medicine health-care product, preparation method and application thereof - Google Patents
Traditional Chinese medicine health-care product, preparation method and application thereof Download PDFInfo
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- CN113907402A CN113907402A CN202111450711.5A CN202111450711A CN113907402A CN 113907402 A CN113907402 A CN 113907402A CN 202111450711 A CN202111450711 A CN 202111450711A CN 113907402 A CN113907402 A CN 113907402A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Abstract
The invention provides a traditional Chinese medicine health-care product, a preparation method and application thereof, and relates to the technical field of health-care products for cigarettes. A traditional Chinese medicine health-care product comprises the following raw materials in parts by weight: 20-30 parts of lily, 10-20 parts of liquorice, 5-10 parts of lotus leaf, 2-5 parts of honeysuckle, 2-5 parts of boat-fruited sterculia seed, 2-5 parts of momordica grosvenori, 2-5 parts of dwarf lilyturf tuber, 2-5 parts of baical skullcap root, 2-5 parts of swordlike atractylodes rhizome, 2-5 parts of aster, 2-5 parts of largehead atractylodes rhizome, 2-5 parts of cyrtomium rhizome, 2-5 parts of mint and 1-3 parts of root of straight ladybell. The product has the comprehensive effects of clearing heat, moistening lung, relieving cough, eliminating phlegm, killing bacteria, removing toxic substance, invigorating spleen and invigorating qi, and can be used in electronic cigarette tobacco tar and conventional cigarette for relieving discomfort of smoking to lung, protecting lung and reducing harm.
Description
Technical Field
The invention relates to the technical field of health products for cigarettes, and particularly relates to a traditional Chinese medicine health product, a preparation method and application thereof.
Background
The traditional cigarette is made of tobacco shreds, has a history for thousands of years, has a vast smoker base in the world, and the cigarette products in the market can release substances such as nicotine, tar, benzene and the like during burning and smoking, thereby bringing great potential safety hazards to smokers and surrounding people. The harm of electron cigarette than traditional cigarette is a lot of little, and the electron cigarette passes through electron smog spinning disk atomiser heating electron cigarette tobacco tar, can produce like the cigarette fog, releases substances such as nicotine and edible essence, and the overwhelming majority of harm of smoking the electron cigarette depends on electron cigarette tobacco tar.
At present, the conventional cigarettes and electronic cigarette tobacco tar in the market are harmful to a certain extent, and smokers are susceptible to diseases such as pharyngitis and pneumonia, so that the technical defect that the conventional cigarettes and electronic cigarette tobacco tar are harmful to human health becomes a problem to be solved by technical staff in the field.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine health-care product which can relieve discomfort caused by smoking to the lung and has a certain protection effect on the lung.
The invention also aims to provide a preparation method of the traditional Chinese medicine health-care product, and the product prepared by the preparation method can fully exert the drug effects of the raw medicinal materials when being applied to the tobacco tar of the electronic cigarette, so that the harm caused by smoking the electronic cigarette is reduced.
The invention also aims to provide a preparation method of the traditional Chinese medicine health-care product, and the product prepared by the preparation method can fully exert the drug effects of the raw medicinal materials when being applied to the traditional cigarette, so that the content of harmful ingredients in the traditional cigarette is reduced.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the embodiment of the application provides a traditional Chinese medicine health-care product, and the dosage of the raw materials is as follows by weight: 20-30 parts of lily, 10-20 parts of liquorice, 5-10 parts of lotus leaf, 2-5 parts of honeysuckle, 2-5 parts of boat-fruited sterculia seed, 2-5 parts of momordica grosvenori, 2-5 parts of dwarf lilyturf tuber, 2-5 parts of baical skullcap root, 2-5 parts of swordlike atractylodes rhizome, 2-5 parts of aster, 2-5 parts of largehead atractylodes rhizome, 2-5 parts of cyrtomium rhizome, 2-5 parts of mint and 1-3 parts of root of straight ladybell.
On the other hand, the embodiment of the application provides a preparation method of a traditional Chinese medicine health-care product, which comprises the following steps:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain Chinese medicinal concentrated solution; adding starch, potassium sorbate and protein powder into the Chinese medicinal concentrated solution, and mixing to obtain the final product.
The traditional Chinese medicine health-care product prepared by the preparation method is applied to the tobacco tar of the electronic cigarette.
In another aspect, an embodiment of the present application further provides a method for preparing a traditional Chinese medicine health product, including the following steps:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain the final product.
Spraying the Chinese medicinal health product prepared by the above preparation method on tobacco leaf or soaking tobacco leaf in the Chinese medicinal health product and sun drying, and then producing traditional cigarette according to normal cigarette process.
The effects of the raw materials are as follows:
lily: has sweet taste and cold nature, and has effects of nourishing yin, moistening lung, clearing heart fire and tranquilizing mind, and can be used for treating chronic cough due to yin deficiency, blood-stained sputum, vexation, pavor, insomnia, dreaminess, and absentmindedness.
Licorice root: the traditional Chinese medicine composition has sweet taste and mild nature, enters heart, lung, spleen and stomach channels, has the functions of tonifying spleen and qi, clearing heat and detoxicating, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing the medicines, and is used for treating weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough and excessive phlegm, abdominal and limb spasm and pain, carbuncle swelling and sore toxicity, and relieving drug toxicity and pungency.
Lotus leaf: bitter taste, neutral nature, entering liver, spleen and stomach meridians, has effects of clearing summer-heat, raising fever, clearing yang, cooling blood and stopping bleeding, and can be used for treating summer-heat polydipsia, summer-heat damp diarrhea, spleen deficiency diarrhea, blood heat hematemesis and epistaxis, hematochezia metrorrhagia and metrostaxis.
Honeysuckle flower: sweet taste and cold nature, enters lung, heart and stomach channels, has the effects of clearing heat and removing toxicity, and cooling and dispersing wind-heat, and is used for treating carbuncle, swelling, furuncle, pharyngitis, erysipelas, heat-toxin and bloody dysentery, wind-heat type common cold, warm disease and fever.
Boat-fruited sterculia seed: has sweet taste and cold nature, enters lung and large intestine channels, has the effects of clearing heat, moistening lung, relieving sore throat, relieving voice, moistening intestine and relaxing bowels, and is used for treating lung heat hoarseness, dry cough without phlegm, dry and painful throat, heat accumulation, constipation, headache and conjunctival congestion.
Momordica grosvenori: cool in nature, sweet in flavor, entering lung channel and large intestine channel, and has the effects of clearing heat, moistening lung, lubricating intestine and relaxing bowels.
Radix ophiopogonis: sweet and slightly bitter in taste and slightly cold in nature, enters heart, lung and stomach channels, has the effects of nourishing yin, promoting the production of body fluid, moistening lung and clearing heart, and is used for treating dry cough due to lung dryness. Cough due to consumptive disease, thirst due to body fluid consumption, insomnia due to vexation, internal heat, diabetes, constipation due to intestinal dryness.
Scutellaria baicalensis: bitter taste and cold nature, and belongs to the channels of lung, gallbladder, spleen, large intestine and small intestine, has the efficacies of clearing heat and drying dampness, purging fire and removing toxicity, stopping bleeding and preventing abortion, and is used for treating damp-warm disease, summer-warm disease, chest distress and nausea, damp-heat fullness, dysentery, jaundice, lung-heat cough, high fever and polydipsia, blood heat and hematemesis, carbuncle swelling and sore toxicity and threatened abortion.
Rhizoma atractylodis: the medicine has pungent and bitter taste and warm nature, has the effects of invigorating spleen, eliminating dampness, dispelling wind and cold and improving eyesight, and is used for treating abdominal distension, diarrhea, edema, beriberi atrophy 36484, rheumatalgia, wind-cold type common cold and night blindness.
Aster root: it is pungent and bitter in taste, warm in nature, enters lung meridian, has effects of moistening lung, descending qi, eliminating phlegm and relieving cough, and can be used for treating excessive phlegm, cough, chronic cough, and cough with hemoptysis.
White atractylodes rhizome: bitter and sweet in taste, warm in nature, entering spleen and stomach meridians, has the effects of strengthening spleen and replenishing qi, eliminating dampness and promoting diuresis, arresting sweating and preventing miscarriage, and is used for treating spleen deficiency and anorexia, abdominal distention and diarrhea, phlegm and fluid retention and dizziness, edema, spontaneous perspiration and threatened abortion.
Rhizoma Osmundae: bitter and astringent taste, cold nature, liver and stomach meridians entered, has effects of killing parasite, clearing heat, removing toxic substance, cooling blood, and stopping bleeding, and can be used for treating wind-heat type common cold, warm macula, hematemesis, hemoptysis, epistaxis, hematochezia, metrorrhagia and metrostaxis, bloody dysentery, leukorrhagia and intestinal parasitosis such as hook, ascaris, tapeworm, etc.
Mint: has pungent taste and cool nature, enters lung and liver meridians, has effects of dispelling pathogenic wind heat, clearing head and eyes, and promoting eruption, and can be used for treating wind-heat type common cold, headache, conjunctival congestion, pharyngitis, aphtha, rubella, measles, and chest and hypochondrium swelling and distress.
Root of straight ladybell: has sweet taste and cold nature, has effects of clearing heat, nourishing yin, moistening lung, and relieving cough, and can be used for treating tracheitis, pertussis, cough due to lung heat, and yellow and thick expectoration.
In the formula components, lily, boat-fruited sterculia seed, momordica grosvenori and ophiopogon root are matched with each other and enter lung channels to play the roles of clearing heat and moistening lung; radix Asteris and radix Adenophorae are matched with each other, so that the decoction has the effects of dissolving phlegm and relieving cough; the lotus leaves, the honeysuckle, the scutellaria baicalensis and the mint are matched with each other, so that the effects of clearing heat and drying dampness can be achieved; the rhizoma Osmundae has antibacterial and toxic materials clearing away effects; the rhizoma atractylodis, the rhizoma atractylodis macrocephalae and the liquorice are matched with each other and enter spleen channels, so that the effects of tonifying spleen and qi can be achieved. The Chinese medicinal herbs are combined and matched with each other, have synergistic interaction, have the comprehensive effects of clearing heat, moistening lung, relieving cough, reducing phlegm, sterilizing, detoxifying, tonifying spleen and replenishing qi, are delicate and lovely in the lung, are worried about and disliked, can relieve the discomfort caused by smoking to the lung, play a certain role in protecting the lung and reduce the harm.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
the lily and lotus leaf health-care tea is prepared from lily, liquorice, lotus leaves, honeysuckle, boat-fruited sterculia seed, momordica grosvenori, dwarf lilyturf tuber, scutellaria baicalensis, rhizoma atractylodis, aster, bighead atractylodes rhizome, cyrtomium rhizome, mint and root of straight ladybell as raw materials, all the raw materials are combined and matched with one another, and the synergistic effect is achieved.
When the traditional Chinese medicine health-care product prepared by the invention is added into the electronic cigarette base oil and is placed in an electronic cigarette, the traditional Chinese medicine health-care product is concentrated and added with starch to become thick, and then the thick liquid is added into the electronic cigarette base oil to form an electronic cigarette tobacco tar blend, so that the consistency of the electronic cigarette tobacco tar is increased, the boiling point of evaporation of the electronic cigarette tobacco tar is reduced, the content of harmful aldehydes generated by alcohols in an atomization process is reduced, and after atomization, beneficial substances in the traditional Chinese medicine health-care product are easy to absorb, and after the traditional Chinese medicine health-care product is inhaled into the lung, the traditional Chinese medicine health-care product has the experience of smoking and the function of moistening the lung, can avoid the damage of the electronic cigarette tobacco tar to the lung, improves the comfort of a smoker in the smoking process, and has higher safety performance.
When the traditional Chinese medicine health-care product prepared by the invention is used for treating tobacco leaves and then manufacturing traditional cigarettes, as the tobacco leaves are hot and dry, a large amount of harmful substances can be generated in the tobacco curing process, the cell structure is damaged along with the loss of the moisture of the tobacco leaves, the membrane permeability is rapidly increased, substances in cells are leaked out, and the effective accumulation of nitrosamine is synchronously increased, but the traditional Chinese medicine health-care product of the invention can clear heat and dry, after the traditional Chinese medicine health-care product is treated, the traditional Chinese medicine health-care product permeates into the tobacco leaves and forms a layer of protective membrane on the surface of the tobacco leaves, so that the tobacco alkaloid existing in the tobacco leaves is blocked from reacting with NOx in the combustion process to generate harmful substances such as nitrosamine and the like in the tobacco leaves, the content of harmful ingredients such as nicotine, tar, CO and the like in the cigarettes can be reduced after the tobacco leaves are fully combusted, the harm to the tobacco leaves is reduced, the harm to the lung in the smoking process is reduced, and the taste of the processed tobacco leaves is soft and sweet, has fragrant smell of Chinese medicinal materials, and can improve quality of tobacco leaf.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
The embodiment of the invention provides a traditional Chinese medicine health-care product, which comprises the following raw materials in parts by weight: 20-30 parts of lily, 10-20 parts of liquorice, 5-10 parts of lotus leaf, 2-5 parts of honeysuckle, 2-5 parts of boat-fruited sterculia seed, 2-5 parts of momordica grosvenori, 2-5 parts of dwarf lilyturf tuber, 2-5 parts of baical skullcap root, 2-5 parts of swordlike atractylodes rhizome, 2-5 parts of aster, 2-5 parts of largehead atractylodes rhizome, 2-5 parts of cyrtomium rhizome, 2-5 parts of mint and 1-3 parts of root of straight ladybell.
In the embodiment, lily, liquorice, lotus leaves, honeysuckle, boat-fruited sterculia seed, momordica grosvenori, radix ophiopogonis, scutellaria baicalensis, rhizoma atractylodis, aster, bighead atractylodes rhizome, cyrtomium fortunei, mint and radix adenophorae are used as raw materials, the raw materials are combined and matched with one another, synergy is realized, the comprehensive effects of clearing heat and moistening lung, relieving cough and reducing sputum, sterilizing and detoxifying, invigorating spleen and replenishing qi are realized, the lung is delicate, moistening and disgusting are favored, the discomfort brought to the lung by smoking can be relieved, a certain protection effect on the lung is realized, and the harm is reduced.
In some embodiments of the present invention, the raw materials are used in the following amounts by weight: 25 parts of lily, 15 parts of liquorice, 8 parts of lotus leaf, 3 parts of honeysuckle, 3 parts of boat-fruited sterculia seed, 3 parts of momordica grosvenori, 3 parts of dwarf lilyturf tuber, 3 parts of baical skullcap root, 3 parts of swordlike atractylodes rhizome, 3 parts of aster, 3 parts of largehead atractylodes rhizome, 3 parts of cyrtomium rhizome, 3 parts of mint and 2 parts of root of straight ladybell.
In some embodiments of the present invention, the raw materials further include, by weight: 1-5 parts of starch, 1-5 parts of potassium sorbate and 1-5 parts of protein powder. When the preservative is applied to the electronic cigarette tobacco tar, starch, potassium sorbate and protein powder are added on the basis of the embodiment, the starch can be used for thickening, the potassium sorbate can be used for preserving freshness, the storage time of the electronic cigarette tobacco tar is prolonged, and the protein powder can increase satiety of a smoker in the using process.
The embodiment of the invention also provides a preparation method of the traditional Chinese medicine health-care product, which comprises the following steps:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain Chinese medicinal concentrated solution; adding starch, potassium sorbate and protein powder into the Chinese medicinal concentrated solution, and mixing to obtain the final product.
In the embodiment, the preparation method is simple and convenient in flow, the prepared traditional Chinese medicine concentrated solution contains a large amount of beneficial substances after decoction and filtration, starch, potassium sorbate and protein powder are added to achieve the effects of thickening, preserving and increasing satiety, and the prepared traditional Chinese medicine health-care product is applied to the field of electronic cigarette tobacco tar.
In some embodiments of the invention, the soaking is performed in water at 50-55 ℃ for 1-1.5 h. After soaking, beneficial ingredients in the raw medicinal materials can be separated out conveniently in the subsequent decocting step.
In some embodiments of the present invention, the weight ratio of the raw materials to the added water amount is 1: (0.8-1.8), decocting until the amount of water is reduced by 60% -65%. The added water amount is less, the situation that the concentration is not enough when the electronic cigarette tobacco tar is used can be avoided, and after decoction, the liquid medicine is concentrated, so that the proportion of beneficial substances in a finished product can be improved, and the taste of the electronic cigarette tobacco tar is richer.
The embodiment of the invention also provides a preparation method of the traditional Chinese medicine health-care product, which comprises the following steps:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain the final product.
In the embodiment, the preparation method is simple and convenient in process, only the raw medicinal materials are decocted and filtered, and the prepared traditional Chinese medicine health-care product is applied to the field of traditional cigarettes.
In some embodiments of the invention, the weight ratio of the raw materials to the added water amount is 1: (8-9) decocting until the amount of water is reduced by 45-50%. After decocting, the liquid medicine is concentrated, so that more beneficial substances in the raw medicinal materials can be extracted, and the proportion of the beneficial substances in the finished product is improved.
The embodiment of the application also provides application of the traditional Chinese medicine health-care product in the tobacco tar of the electronic cigarette, and the traditional Chinese medicine health-care product is added into the base oil of the electronic cigarette and is placed in the electronic cigarette
In the above embodiment, the traditional Chinese medicine health care product is concentrated and becomes thick after being added with starch, and is added into the electronic cigarette base oil, so that an electronic cigarette tobacco tar blend is formed, the consistency of the electronic cigarette tobacco tar is increased, the boiling point of evaporation of the electronic cigarette tobacco tar is reduced, the content of harmful aldehyde substances generated by alcohol substances in the atomization process is reduced, and after atomization, beneficial substances in the traditional Chinese medicine health care product are favorable for absorption, after the traditional Chinese medicine health care product is inhaled into the lung, the traditional Chinese medicine health care product has the experience of smoking and can play a role in moistening the lung, the damage of the electronic cigarette tobacco tar to the lung can be avoided, the comfort of a smoker in the smoking process is improved, and the traditional Chinese medicine health care product has higher safety performance.
The embodiment of the application also provides application of the traditional Chinese medicine health-care product in the traditional cigarette, the prepared traditional Chinese medicine health-care product is sprayed on tobacco leaves or the tobacco leaves are soaked in the traditional Chinese medicine health-care product and then dried in the sun, and then the traditional cigarette is produced according to a normal cigarette process.
In the embodiment, because the tobacco leaves are hot and dry, a large amount of harmful substances are generated in the tobacco curing process, the cell structure is damaged along with the loss of the moisture of the tobacco leaves, the permeability of the membrane is rapidly increased, the substances in the cells are externally permeated, the effective accumulation of the nitrosamine is synchronously increased, and the traditional Chinese medicine health-care product can clear heat and dry dampness, after the treatment, the Chinese medicinal health product permeates into tobacco leaf, and forms a layer of protective film on tobacco leaf surface, in the process of flue-curing tobacco, prevents tobacco alkaloid in tobacco leaf from reacting with NOx in combustion process to generate nitrosamine and other harmful substances, can reduce the content of nicotine, tar and CO and other harmful components in cigarette after full combustion, is beneficial to reducing harm and tar of cigarette, reduces the harm to lung in the smoking process, the processed tobacco leaves are soft and sweet in taste, have faint scent of traditional Chinese medicines, and can improve the quality of the tobacco leaves.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
A traditional Chinese medicine health product is prepared by the following steps:
soaking 25g of lily, 15g of liquorice, 8g of lotus leaf, 3g of honeysuckle, 3g of boat-fruited sterculia seed, 3g of momordica grosvenori, 3g of dwarf lilyturf tuber, 3g of baical skullcap root, 3g of swordlike atractylodes rhizome, 3g of aster, 3g of largehead atractylodes rhizome, 3g of cyrtomium rhizome, 3g of mint and 2g of root of straight ladybell in water at 52 ℃ for 1.2h, adding 104g of water for decocting until the amount of the water is reduced by 62%, and filtering to obtain a traditional Chinese medicine concentrated solution;
adding 3g of starch, 3g of potassium sorbate and 3g of protein powder into the Chinese medicinal concentrated solution, and uniformly mixing to obtain the Chinese medicinal health product.
The traditional Chinese medicine health-care product is added into the base oil of the electronic cigarette and is placed in the electronic cigarette.
Example 2
A traditional Chinese medicine health product is prepared by the following steps:
soaking 20g of lily, 10g of liquorice, 5g of lotus leaf, 2g of honeysuckle, 2g of boat-fruited sterculia seed, 2g of momordica grosvenori, 2g of dwarf lilyturf tuber, 2g of baical skullcap root, 2g of swordlike atractylodes rhizome, 2g of aster, 2g of largehead atractylodes rhizome, 2g of cyrtomium rhizome, 2g of mint and 1g of root of straight ladybell in water at the temperature of 50 ℃ for 1.5h, adding 68g of water for decoction, and filtering to obtain a traditional Chinese medicine concentrated solution after the water amount is reduced by 60%;
adding 1g of starch, 1g of potassium sorbate and 1g of protein powder into the Chinese medicinal concentrated solution, and mixing uniformly to obtain the Chinese medicinal health product.
The traditional Chinese medicine health-care product is added into the base oil of the electronic cigarette and is placed in the electronic cigarette.
Example 3
A traditional Chinese medicine health product is prepared by the following steps:
soaking 30g of lily, 20g of liquorice, 10g of lotus leaf, 5g of honeysuckle, 5g of boat-fruited sterculia seed, 5g of momordica grosvenori, 5g of dwarf lilyturf tuber, 5g of baical skullcap root, 5g of swordlike atractylodes rhizome, 5g of aster, 5g of largehead atractylodes rhizome, 5g of cyrtomium rhizome, 5g of mint and 3g of root of straight ladybell in water at the temperature of 55 ℃ for 1.0h, adding 113g of water for decocting until the amount of the water is reduced by 65%, and filtering to obtain a traditional Chinese medicine concentrated solution;
adding 5g of starch, 5g of potassium sorbate and 1g of protein powder into the Chinese medicinal concentrated solution, and mixing uniformly to obtain the Chinese medicinal health product.
The traditional Chinese medicine health-care product is added into the base oil of the electronic cigarette and is placed in the electronic cigarette.
Example 4
A traditional Chinese medicine health product is prepared by the following steps:
soaking 25g of lily, 15g of liquorice, 8g of lotus leaf, 3g of honeysuckle, 3g of boat-fruited sterculia seed, 3g of momordica grosvenori, 3g of dwarf lilyturf tuber, 3g of baical skullcap root, 3g of swordlike atractylodes rhizome, 3g of aster, 3g of largehead atractylodes rhizome, 3g of cyrtomium rhizome, 3g of mint and 2g of root of straight ladybell, adding 680g of water, decocting until the water amount is reduced by 48%, and filtering to obtain the traditional Chinese medicine health-care product.
Spraying the prepared traditional Chinese medicine health product on tobacco leaves to moisten the surfaces of the tobacco leaves, and then producing the traditional cigarettes according to a normal cigarette process.
Example 5
A traditional Chinese medicine health product is prepared by the following steps:
soaking 20g of lily, 10g of liquorice, 5g of lotus leaf, 2g of honeysuckle, 2g of boat-fruited sterculia seed, 2g of momordica grosvenori, 2g of dwarf lilyturf tuber, 2g of baical skullcap root, 2g of swordlike atractylodes rhizome, 2g of aster, 2g of largehead atractylodes rhizome, 2g of cyrtomium rhizome, 2g of mint and 1g of root of straight ladybell, adding 504g of water, decocting until the amount of water is reduced by 45%, and filtering to obtain the traditional Chinese medicine health-care product.
Spraying the prepared traditional Chinese medicine health product on tobacco leaves to moisten the surfaces of the tobacco leaves, and then producing the traditional cigarettes according to a normal cigarette process.
Example 6
A traditional Chinese medicine health product is prepared by the following steps:
soaking 30g of lily, 20g of liquorice, 10g of lotus leaf, 5g of honeysuckle, 5g of boat-fruited sterculia seed, 5g of momordica grosvenori, 5g of dwarf lilyturf tuber, 5g of baical skullcap root, 5g of swordlike atractylodes rhizome, 5g of aster, 5g of largehead atractylodes rhizome, 5g of cyrtomium rhizome, 5g of mint and 3g of root of straight ladybell, adding 904g of water, decocting until the amount of water is reduced by 50%, and filtering to obtain the traditional Chinese medicine health-care product.
Soaking tobacco leaf in the Chinese medicinal health product, sun drying, and producing conventional cigarette according to normal cigarette process.
Examples of the experiments
Firstly, analysis of harmful components of the traditional Chinese medicine health product when applied to traditional cigarettes
Selecting tobacco leaves (manufactured by Xinzheng cigarette factory of tobacco industry Limited liability company in Henan), dividing the tobacco leaves into 4 groups, treating 1-3 groups with the traditional Chinese medicine health care products prepared in the embodiments 4-6, not treating the 4 th group, producing cigarettes according to the traditional cigarette process for each group, and respectively measuring the main stream smoke of cigarettes and 7 harmful components in the cigarettes according to related industry and national standards, wherein the measurement results are shown in tables 1 and 2.
TABLE 1 cigarette mainstream smoke component test results
As can be seen from Table 1, when the tobacco leaves treated by the traditional Chinese medicine health-care product prepared by the invention are used for making cigarettes, the total grain phase substances, the nicotine content and the tar content in the cigarettes are reduced compared with the content of the tobacco leaves which are not treated and directly made into the cigarettes, and the harm can be reduced when the traditional Chinese medicine health-care product is applied to the traditional cigarettes.
TABLE 2 cigarette smoke 7 harmful ingredient detection results
As can be seen from Table 2, when the tobacco leaves treated by the traditional Chinese medicine health-care product prepared by the invention are used for making cigarettes, the contents of phenol, HCN, ammonia and CO in the cigarettes are reduced compared with the contents of phenol, HCN, ammonia and CO in the cigarettes directly made from the tobacco leaves which are not treated, and the contents of harmful ingredients can be reduced to a certain extent when the traditional Chinese medicine health-care product is applied to the traditional cigarettes.
(II) testing the content of aldehyde substances in smoke generated when the traditional Chinese medicine health-care product is applied to the tobacco tar of the electronic cigarette
The content of aldehydes in smoke generated when the traditional Chinese medicine health-care product prepared in the examples 1-3 is applied to the electronic cigarette as the electronic cigarette tobacco tar is measured by adopting a high performance liquid chromatography according to the industry standard, meanwhile, a control group is arranged, the control group adopts the commercial electronic cigarette tobacco tar (the main components are polyethylene glycol, glycerin, tobacco extract, nicotine, tobacco essence and propylene glycol), and the measurement results are shown in table 3.
TABLE 3
Group of | Formaldehyde (ng/200puffs) | Acetaldehyde (ng/200puffs) | Acrolein (ng/200puffs) |
Example 1 | Not detected out | 0.0001 | 0.0005 |
Example 2 | Not detected out | 0.0002 | 0.0007 |
Example 3 | Not detected out | 0.0001 | 0.0007 |
Control group | 0.02 | 0.15 | 0.10 |
As can be seen from table 3, the traditional Chinese medicine health products prepared in examples 1 to 3 of the present invention have no formaldehyde content detected in smoke generated when applied to electronic cigarette smoke, and the acetaldehyde and acrolein contents are significantly reduced compared to the conventional electronic cigarette smoke, which indicates that after the traditional Chinese medicine health products prepared in the present invention are added, the generation of harmful aldehydes can be reduced, and the traditional Chinese medicine health products have higher safety performance.
In conclusion, the invention provides a traditional Chinese medicine health-care product which is prepared from lily, liquorice, lotus leaves, honeysuckle, boat-fruited sterculia seed, momordica grosvenori, ophiopogon root, scutellaria baicalensis, rhizoma atractylodis, aster, bighead atractylodes rhizome, cyrtomium rhizome, mint and adenophora stricta serving as raw materials, wherein the raw materials are combined and matched with one another to realize synergistic interaction, so that the traditional Chinese medicine health-care product has the comprehensive effects of clearing heat, moistening lung, relieving cough, reducing phlegm, sterilizing, detoxifying, tonifying spleen and tonifying qi, is moist and dry in the lung and can relieve discomfort caused by smoking to the lung, protect the lung to a certain extent and reduce harm.
When the traditional Chinese medicine health-care product prepared by the invention is added into electronic cigarette base oil and placed in an electronic cigarette, the traditional Chinese medicine health-care product is concentrated and added with starch to become thick, and the thick mixture is added into the electronic cigarette base oil to form an electronic cigarette tobacco tar blend, so that the consistency of the electronic cigarette tobacco tar is increased, and the evaporation boiling point of the electronic cigarette tobacco tar is reduced, so that the content of harmful aldehydes substances generated by alcohol substances in the atomization process is reduced.
In addition, the invention also provides an application of the traditional Chinese medicine health product in the traditional cigarette, when the traditional Chinese medicine health product prepared by the invention is used for treating the tobacco leaves and then manufacturing the traditional cigarette, as the tobacco leaves are hot and dry, a large amount of harmful substances can be generated in the tobacco curing process, the cell structure is damaged along with the loss of the tobacco leaves, the membrane permeability is rapidly increased, the substances in the cells are externally permeated, and the effective accumulation of the nitrosamine is synchronously increased, but the traditional Chinese medicine health product of the invention can clear heat and dry dampness, after the treatment, the traditional Chinese medicine health product permeates into the tobacco leaves, and a layer of protective membrane is formed on the surface of the tobacco leaves, so that the tobacco alkaloid in the tobacco leaves is blocked from reacting with NOx in the combustion process to generate the harmful substances such as the nitrosamine and the like in the tobacco leaves in the process of curing, the content of the harmful ingredients such as nicotine, tar, CO and the like in the cigarette can be reduced after the tobacco is fully combusted, the harm and the tar reduction of the cigarette is facilitated, the harm to the lung in the smoking process is reduced, and the processed tobacco leaves are soft and sweet in taste, have faint scent of traditional Chinese medicines, and can improve the quality of the tobacco leaves.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. A traditional Chinese medicine health product is characterized by comprising the following raw materials in parts by weight: 20-30 parts of lily, 10-20 parts of liquorice, 5-10 parts of lotus leaf, 2-5 parts of honeysuckle, 2-5 parts of boat-fruited sterculia seed, 2-5 parts of momordica grosvenori, 2-5 parts of dwarf lilyturf tuber, 2-5 parts of baical skullcap root, 2-5 parts of swordlike atractylodes rhizome, 2-5 parts of aster, 2-5 parts of largehead atractylodes rhizome, 2-5 parts of cyrtomium rhizome, 2-5 parts of mint and 1-3 parts of root of straight ladybell.
2. The traditional Chinese medicine health product according to claim 1, wherein the raw materials are used in the following amounts in parts by weight: 25 parts of lily, 15 parts of liquorice, 8 parts of lotus leaf, 3 parts of honeysuckle, 3 parts of boat-fruited sterculia seed, 3 parts of momordica grosvenori, 3 parts of dwarf lilyturf tuber, 3 parts of baical skullcap root, 3 parts of swordlike atractylodes rhizome, 3 parts of aster, 3 parts of largehead atractylodes rhizome, 3 parts of cyrtomium rhizome, 3 parts of mint and 2 parts of root of straight ladybell.
3. The traditional Chinese medicine health product of claim 1, wherein the raw materials further comprise, in parts by weight: 1-5 parts of starch, 1-5 parts of potassium sorbate and 1-5 parts of protein powder.
4. A method for preparing a health product of a traditional Chinese medicine according to any one of claims 1 to 3, comprising the steps of:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain Chinese medicinal concentrated solution;
adding starch, potassium sorbate and protein powder into the Chinese medicinal concentrated solution, and mixing to obtain the final product.
5. The method for preparing a health product of Chinese herbs in accordance with claim 4, wherein the soaking is carried out in water at 50-55 ℃ for 1-1.5 h.
6. The method for preparing a health product of Chinese herbs according to claim 4, wherein the weight ratio of the raw materials to the added water is 1: (0.8-1.8), decocting until the amount of water is reduced by 60% -65%.
7. A method for preparing a health product of a traditional Chinese medicine according to any one of claims 1-2, comprising the steps of:
soaking Bulbus Lilii, Glycyrrhrizae radix, folium Nelumbinis, flos Lonicerae, semen Scaphii Lychnophori, fructus Siraitiae Grosvenorii, radix Ophiopogonis, Scutellariae radix, rhizoma Atractylodis, radix Asteris, Atractylodis rhizoma, rhizoma Osmundae, herba Menthae and radix Adenophorae, decocting in water, and filtering to obtain the final product.
8. The method for preparing a health product of Chinese herbs according to claim 7, wherein the weight ratio of the raw materials to the added water is 1: (8-9) decocting until the amount of water is reduced by 45-50%.
9. An application of a traditional Chinese medicine health product in electronic cigarette tobacco tar is characterized in that the traditional Chinese medicine health product is prepared by the preparation method of any one of claims 4 to 6, and is added into the electronic cigarette base oil and placed in an electronic cigarette.
10. The application of a traditional Chinese medicine health product in traditional cigarettes is characterized in that the traditional Chinese medicine health product is prepared by the preparation method of any one of claims 7 to 8, and is sprayed on tobacco leaves or the tobacco leaves are soaked in the traditional Chinese medicine health product and then dried in the sun, and then the traditional cigarettes are produced according to a normal cigarette process.
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101461565A (en) * | 2009-01-08 | 2009-06-24 | 华健 | Medicinal health type tobacco juice for electronic smoke |
CN104126865A (en) * | 2014-07-11 | 2014-11-05 | 深圳市汇金禾生物制剂有限公司 | Preparation formula and method of cigarette poison reducing liquid and method for reducing tobacco toxicity |
CN106036991A (en) * | 2016-06-01 | 2016-10-26 | 熊轶 | Electronic cigarette tobacco tar with efficacies of clearing away lung-heat and moistening throat and preparation method of electronic cigarette tobacco tar |
CN113577144A (en) * | 2021-08-19 | 2021-11-02 | 广西馨海药业科技有限公司 | A composition with effect in improving respiratory system inflammation and its preparation method |
-
2021
- 2021-11-30 CN CN202111450711.5A patent/CN113907402A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101461565A (en) * | 2009-01-08 | 2009-06-24 | 华健 | Medicinal health type tobacco juice for electronic smoke |
CN104126865A (en) * | 2014-07-11 | 2014-11-05 | 深圳市汇金禾生物制剂有限公司 | Preparation formula and method of cigarette poison reducing liquid and method for reducing tobacco toxicity |
CN106036991A (en) * | 2016-06-01 | 2016-10-26 | 熊轶 | Electronic cigarette tobacco tar with efficacies of clearing away lung-heat and moistening throat and preparation method of electronic cigarette tobacco tar |
CN113577144A (en) * | 2021-08-19 | 2021-11-02 | 广西馨海药业科技有限公司 | A composition with effect in improving respiratory system inflammation and its preparation method |
Non-Patent Citations (2)
Title |
---|
罗安伟等: "《食品安全保藏学第三版》", 31 December 2019, 中国轻工业出版社 * |
老中医养生堂: "《药食同源中药材药理研究与应用》", 辽宁科学技术出版社 * |
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