CN113876638A - High-stability skin-care moisturizing particle essence and preparation method thereof - Google Patents
High-stability skin-care moisturizing particle essence and preparation method thereof Download PDFInfo
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- CN113876638A CN113876638A CN202111208637.6A CN202111208637A CN113876638A CN 113876638 A CN113876638 A CN 113876638A CN 202111208637 A CN202111208637 A CN 202111208637A CN 113876638 A CN113876638 A CN 113876638A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 11
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- 239000002562 thickening agent Substances 0.000 claims abstract description 25
- 239000003906 humectant Substances 0.000 claims abstract description 24
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 22
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 20
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- 238000003756 stirring Methods 0.000 claims description 25
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 14
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 claims description 12
- 229940093497 ergothioneine Drugs 0.000 claims description 11
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
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- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 5
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 5
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 5
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 239000008117 stearic acid Substances 0.000 claims description 5
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
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- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a high-stability skin-care moisturizing particle essence which comprises the following components in parts by weight: 5-15 parts of a humectant, 0.2-0.5 part of a thickener, 10-20 parts of an emollient, 0.5-1 part of an antioxidant, 0.1-0.5 part of a pH regulator, 5-10 parts of a skin conditioner and 60-80 parts of deionized water. The invention relates to the technical field of skin care essence, and particularly provides a high-stability skin care moisturizing particle essence and a preparation method thereof, which solve the technical problems that the moisturizing degree of a common aqueous agent system formula and a plurality of fatting agents cannot be normally added, and the functions of long-term stable preservation and application can be achieved by wrapping individual active ingredients in the system by a plurality of oily fatting agents under a specific process state; secondly, the formula of the system can effectively improve the moisture retention of the aqueous formula and improve the effect of actual use.
Description
Technical Field
The invention relates to the technical field of skin care essence, in particular to high-stability skin care and moisturizing particle essence and a preparation method thereof.
Background
With the continuous improvement of living standard of people, many people can unconsciously take in excessive sugar, and the brown protein generated by combining the sugar which can not be absorbed and protein can directly influence the skin state, so that the skin becomes rough, dark and lusterless; meanwhile, with the continuous development of science and technology, various pollutions are increased, the concentration of free radicals generated by the continuous contact of the human body and the outside is greatly increased, and the oxidative attack of excessive free radicals cannot be counteracted by cells of the human body, so that the skin becomes loose, wrinkles are generated, and aging is catalyzed.
However, the essence on the market is water-oil emulsion, and some essence or essential oil of plant extraction origin needs to be added in the essence processing process in order to cover the taste of the material.
Disclosure of Invention
In order to overcome the defects, the invention provides the skin-care moisturizing particle essence which can quickly replenish water, has excellent moisturizing performance and high stability and the preparation method thereof.
The invention provides the following technical inventions: the invention provides a high-stability skin-care moisturizing particle essence which comprises the following components in parts by weight: 5-15 parts of a humectant, 0.2-0.5 part of a thickener, 10-20 parts of an emollient, 0.5-1 part of an antioxidant, 0.1-0.5 part of a pH regulator, 5-10 parts of a skin conditioner and 60-80 parts of deionized water.
Preferably, the skin care and moisturizing particle essence with high stability comprises the following components in parts by weight: 8-12 parts of a humectant, 0.3-0.4 part of a thickener, 13-17 parts of an emollient, 0.7-0.8 part of an antioxidant, 0.2-0.4 part of a pH regulator, 6-9 parts of a skin conditioner and 65-75 parts of deionized water.
Preferably, the skin care and moisturizing particle essence with high stability comprises the following components in parts by weight: 10 parts of humectant, 0.35 part of thickener, 15 parts of emollient, 0.75 part of antioxidant, 0.3 part of pH regulator, 7.5 parts of skin conditioner and 70 parts of deionized water.
Further, the humectant comprises 3-7 parts of glycerol, 2-5 parts of fucoidin-H, 3-5 parts of neopentyl glycol didecanoate, 1-3 parts of glycerol tri (ethyl hexanoate), 1-2 parts of damnacanthate, 1-5 parts of propylene glycol and 0.1-0.5 part of Bridgkin fruit oil.
Further, the thickening agent comprises 0.1-0.3 part of xanthan gum, 0.1-0.3 part of carbomer and 1-3 parts of behenyl alcohol.
Further, the emollient comprises 0.5-2 parts of 1, 2-hexanediol, 0.05-0.2 part of carnosine, 1-3 parts of liquid organic silicon and 0.1-1 part of oryzanol.
Further, the antioxidant comprises 0.5-1 part of p-hydroxyacetophenone, 0.1-0.5 part of astaxanthin and 0.01-0.05 part of ergothioneine.
Further, the pH regulator is triethanolamine.
Further, the skin conditioner comprises 1-3 parts of stearic acid and 1-3 parts of ethylhexyl hydroxystearate.
The invention relates to a preparation method of a high-stability skin-care moisturizing particle essence, which specifically comprises the following steps:
step one, well doing sanitary cleaning work, strictly cleaning and disinfecting equipment and utensils;
step two, adding the humectant and the thickener into deionized water at the temperature of 80-85 ℃, uniformly stirring, and cooling to 45 ℃;
step three, heating the emollient and the skin conditioner to 80 ℃, uniformly stirring, and cooling to 75 ℃;
step four, adding the humectant and the thickener which are uniformly mixed in the step two into the emollient and the skin conditioner in the step three, stirring at a medium speed until no oil phase exists on the surface, and controlling to stir at a slow speed;
step five, adding the antioxidant, and uniformly stirring at a slow speed;
and step six, adding a pH regulator, and regulating the pH to 5-5.5 to obtain a finished product.
Haematococcus gel-H: the Fucus vesiculosus extract contains glutamic acid which can increase the softness and smoothness of skin, effectively nourish skin, provide sebum membrane for skin, protect skin, and help the metabolism of fat cells and the regeneration of connective tissues. The minerals, vitamins and polyphenols contained therein stimulate the body's natural healing process.
Carnosine: is a dipeptide composed of beta-alanine and L-histidine, and naturally exists in various tissues of the body. Can resist free radical damage, remove free radical, and achieve antioxidant effect; carnosine can also achieve the effect of delaying aging by protecting mitochondrial function and reducing the generation of ROS; can also react with active substances in vivo to protect protein from glycosylation, and has anti-glycation effect.
Oryzanol: can accelerate blood circulation and metabolism of skin, and has effects of nourishing skin, preventing skin aging, and promoting skin health.
Ergothioneine: ergothioneine (L-Ergothionine, EGT) with the chemical name of 2-sulfydryl histidine trimethyl inner salt is the only known natural 2-thioimidazole amino acid (2-thio-imidazole) to date. The human epidermis is composed of stratum corneum cells, melanocytes, and fibroblasts, all of which express ETT, a transporter of EGT, and thus can absorb and accumulate EGT. The EGT has the absorption wavelength similar to that of DNA in the ultraviolet absorption range, and can effectively prevent the damage caused by ultraviolet radiation; meanwhile, EGT has strong oxidation resistance, can ensure that 70 percent of cells still have reducibility under the condition of continuous irradiation of ultraviolet rays for 18 hours, and can also inhibit the formation of various active oxides, lipid peroxidation and apoptosis of irradiated cells. In addition, EGT has good chemical stability, can be accumulated in epidermal cells, and is nontoxic. Therefore, the EGT has wide application prospect in the cosmetic industry, and has the effects of preventing radiation, whitening, reducing wrinkles, removing acnes and pouches, shrinking pores, delaying senescence and the like.
Tangeretin macrocarpa ester: the components of the oil are sweet almond oil, tangerine peel oil and sweet almond oil, contain various vitamins, proteins, polyunsaturated fatty acids, mineral substances and glucoside, are base oil which is quite soft, smooth and not greasy, have the function of isolating ultraviolet rays, have the characteristics of being mild and easy to absorb, and have the functions of nourishing and moisturizing, and relieving and resisting allergy; meanwhile, the tangerine peel oil effectively covers the unpleasant odor of the product, improves the sensory quality of the product and also can improve the health state of the skin.
Astaxanthin: is a final product of carotenoid synthesis, is a haematochrome which is widely existed in organisms, is difficult to artificially and chemically synthesize and has a cis-structure mostly. It is a very potent antioxidant vitamin in nature, with the reputation of "super vitamin E", and is effective in protecting the skin from ultraviolet (UVA, UVB) rays, consuming putrescine when the skin is exposed to light, as a potential photo-protective agent for preventing photoaging of the skin and inducing skin cancer. It has strong ability of eliminating free radicals, and can prevent skin cells from being damaged by free radicals, and reduce wrinkle and freckle.
Buric fruit oil: the main component is the oil of Daphnia lansium Hemsl. The oil is rich in oleic acid, linoleic acid, palmitic acid, carotenoid, VE, VC and the like, has good permeability, can nourish the skin, and has good stability and good moisturizing effect.
The invention adopting the components has the following beneficial effects: the invention provides a high-stability skin-care moisturizing particle essence and a preparation method thereof, which solve the technical problems that the moisturizing degree of a common aqueous agent system formula and a plurality of fatting agents cannot be normally added, and the functions of long-term stable preservation and application can be achieved by wrapping individual active ingredients in the system by a plurality of oily fatting agents under a specific process state; secondly, the formula of the system can effectively improve the moisture retention of the aqueous formula and improve the effect of actual use.
Detailed Description
The technical invention in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
a high-stability skin-care moisturizing particle essence comprises the following components in parts by weight: 5 parts of humectant, 0.2 part of thickener, 10 parts of emollient, 0.5 part of antioxidant, 0.1 part of pH regulator, 5 parts of skin conditioner and 60 parts of deionized water.
The humectant comprises 3 parts of glycerol, 2 parts of fucoidin-H, 3 parts of neopentyl glycol didecanoate, 1 part of glycerol tri (ethyl hexanoate), 1 part of tangeretin, 1 part of propylene glycol and 0.1 part of Bridgkin fruit oil. The thickener comprises 0.1 part of xanthan gum, 0.1 part of carbomer and 1 part of behenyl alcohol. The emollient comprises 0.5 parts of 1, 2-hexanediol, 0.05 parts of carnosine, 1 part of liquid organic silicon and 0.1 part of oryzanol. The antioxidant comprises 0.5 part of p-hydroxyacetophenone, 0.1 part of astaxanthin and 0.01 part of ergothioneine. The pH regulator is triethanolamine. The skin conditioner includes 1 part of stearic acid and 1 part of ethylhexyl hydroxystearate.
The invention relates to a preparation method of a high-stability skin-care moisturizing particle essence, which specifically comprises the following steps:
step one, well doing sanitary cleaning work, strictly cleaning and disinfecting equipment and utensils;
step two, adding the humectant and the thickener into deionized water at the temperature of 80-85 ℃, uniformly stirring, and cooling to 45 ℃;
step three, heating the emollient and the skin conditioner to 80 ℃, uniformly stirring, and cooling to 75 ℃;
step four, adding the humectant and the thickener which are uniformly mixed in the step two into the emollient and the skin conditioner in the step three, stirring at a medium speed until no oil phase exists on the surface, and controlling to stir at a slow speed;
step five, adding the antioxidant, and uniformly stirring at a slow speed;
and step six, adding a pH regulator, and regulating the pH to 5-5.5 to obtain a finished product.
Example 2
The invention provides a high-stability skin-care moisturizing particle essence which comprises the following components in parts by weight: 10 parts of humectant, 0.35 part of thickener, 15 parts of emollient, 0.75 part of antioxidant, 0.3 part of pH regulator, 7.5 parts of skin conditioner and 70 parts of deionized water.
The humectant comprises 5 parts of glycerol, 3.5 parts of fucoidin-H, 4 parts of neopentyl glycol didecanoate, 2 parts of glycerol tri (ethyl hexanoate), 1.5 parts of tangeretin, 3 parts of propylene glycol and 0.3 part of Bridgkin fruit oil. The thickener comprises 0.2 parts of xanthan gum, 0.2 parts of carbomer and 2 parts of behenyl alcohol. The emollient comprises 1.25 parts of 1, 2-hexanediol, 0.125 parts of carnosine, 2 parts of liquid organosilicon and 0.55 part of oryzanol. The antioxidant comprises 0.75 parts of p-hydroxyacetophenone, 0.3 parts of astaxanthin and 0.03 parts of ergothioneine. The pH regulator is triethanolamine. The skin conditioner includes 2 parts stearic acid and 2 parts ethylhexyl hydroxystearate.
The invention relates to a preparation method of a high-stability skin-care moisturizing particle essence, which specifically comprises the following steps:
step one, well doing sanitary cleaning work, strictly cleaning and disinfecting equipment and utensils;
step two, adding the humectant and the thickener into deionized water at the temperature of 80-85 ℃, uniformly stirring, and cooling to 45 ℃;
step three, heating the emollient and the skin conditioner to 80 ℃, uniformly stirring, and cooling to 75 ℃;
step four, adding the humectant and the thickener which are uniformly mixed in the step two into the emollient and the skin conditioner in the step three, stirring at a medium speed until no oil phase exists on the surface, and controlling to stir at a slow speed;
step five, adding the antioxidant, and uniformly stirring at a slow speed;
and step six, adding a pH regulator, and regulating the pH to 5-5.5 to obtain a finished product.
Example 3
The invention provides a high-stability skin-care moisturizing particle essence which comprises the following components in parts by weight: 15 parts of humectant, 0.5 part of thickener, 20 parts of emollient, 1 part of antioxidant, 0.5 part of pH regulator, 10 parts of skin conditioner and 80 parts of deionized water.
The humectant comprises 7 parts of glycerol, 5 parts of fucoidin-H, 5 parts of neopentyl glycol didecanoate, 3 parts of glycerol tri (ethyl hexanoate), 2 parts of tangeretin, 5 parts of propylene glycol and 0.5 part of Bridgkin fruit oil. The thickener comprises 0.3 parts of xanthan gum, 0.3 parts of carbomer and 3 parts of behenyl alcohol. The emollient comprises 2 parts of 1, 2-hexanediol, 0.2 part of carnosine, 3 parts of liquid organic silicon and 1 part of oryzanol. The antioxidant comprises 1 part of p-hydroxyacetophenone, 0.5 part of astaxanthin and 0.05 part of ergothioneine. The pH regulator is triethanolamine. The skin conditioner includes 3 parts stearic acid and 3 parts ethylhexyl hydroxystearate.
The invention relates to a preparation method of a high-stability skin-care moisturizing particle essence, which specifically comprises the following steps:
step one, well doing sanitary cleaning work, strictly cleaning and disinfecting equipment and utensils;
step two, adding the humectant and the thickener into deionized water at the temperature of 80-85 ℃, uniformly stirring, and cooling to 45 ℃;
step three, heating the emollient and the skin conditioner to 80 ℃, uniformly stirring, and cooling to 75 ℃;
step four, adding the humectant and the thickener which are uniformly mixed in the step two into the emollient and the skin conditioner in the step three, stirring at a medium speed until no oil phase exists on the surface, and controlling to stir at a slow speed;
step five, adding the antioxidant, and uniformly stirring at a slow speed;
and step six, adding a pH regulator, and regulating the pH to 5-5.5 to obtain a finished product.
The high-stability skin-care moisturizing particle essence provided by the scheme is brought into 14 women and 16 men with ages of 18-65 years, the moisture content of the horny layer of a forearm test area is 15-45 (Comeometer Unit, C.U), the 14 women and the 16 men are used as subjects for tests, according to a random table, the inner side of one forearm is randomly selected as a sample area, the other side of the forearm is used as a blank control area, and the sample area uses a test sample according to the (2.0 +/-0.1) mg/cm2The amount of the skin cuticle moisture content is measured by a skin moisture measuring probe, the larger the measured value is, the higher the skin cuticle moisture content is, and the measuring result is shown in the following table:
note: t0 in the table represents the stratum corneum moisture content at the start of the test.
From the above test results, it can be seen that, after sample application for 1h, the moisture content of stratum corneum in the area where 30 subjects applied the ergothioneine double-antibody essence was significantly different from that before sample application, wherein the moisture content of stratum corneum of example 1 was increased by 63.39%, the moisture content of stratum corneum of example 2 was increased by 65.31%, and the moisture content of stratum corneum of example 3 was increased by 64.53%; the water content of the skin cutin in the blank control area is increased by 1.94%; there was a significant difference between the two sets of data for the sample area and the blank area.
After 2h of using the sample, the moisture content of the stratum corneum in the area of 30 subjects coated with the ergothioneine double-antibody essence is significantly different from that before using the sample, wherein the moisture content of the stratum corneum of example 1 is increased by 51.31%, the moisture content of the stratum corneum of example 2 is increased by 51.99%, and the moisture content of the stratum corneum of example 3 is increased by 50.62%; the water content of the skin cutin in the blank control area is increased by 2.08 percent; there was a significant difference between the two sets of data for the sample area and the blank area.
After 3h of using the sample, the moisture content of the stratum corneum in the area of 30 subjects coated with the ergothioneine double-antibody essence is significantly different from that before using the sample, wherein the moisture content of the stratum corneum of example 1 is increased by 48.23%, the moisture content of the stratum corneum of example 2 is increased by 48.56%, and the moisture content of the stratum corneum of example 3 is increased by 48.33%; the water content of the skin cutin in the blank control area is increased by 0.61%; there was a significant difference between the two sets of data for the sample area and the blank area.
After 4h of using the sample, the moisture content of the stratum corneum in the area of 30 subjects coated with the ergothioneine double-antibody essence is significantly different from that before using the sample, wherein the moisture content of the stratum corneum of example 1 is increased by 40.95%, the moisture content of the stratum corneum of example 2 is increased by 41.51%, and the moisture content of the stratum corneum of example 3 is increased by 41.18%; the water content of the skin cutin in the blank control area is increased by 0.69%; there was a significant difference between the two sets of data for the sample area and the blank area.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. The high-stability skin-care moisturizing particle essence is characterized by comprising the following components in parts by weight: 5-15 parts of a humectant, 0.2-0.5 part of a thickener, 10-20 parts of an emollient, 0.5-1 part of an antioxidant, 0.1-0.5 part of a pH regulator, 5-10 parts of a skin conditioner and 60-80 parts of deionized water.
2. The high-stability skin-care moisturizing essence according to claim 1, which comprises the following components in parts by weight: 8-12 parts of a humectant, 0.3-0.4 part of a thickener, 13-17 parts of an emollient, 0.7-0.8 part of an antioxidant, 0.2-0.4 part of a pH regulator, 6-9 parts of a skin conditioner and 65-75 parts of deionized water.
3. The high-stability skin-care moisturizing essence according to claim 1, wherein the high-stability skin-care moisturizing essence comprises the following components in parts by weight: 10 parts of humectant, 0.35 part of thickener, 15 parts of emollient, 0.75 part of antioxidant, 0.3 part of pH regulator, 7.5 parts of skin conditioner and 70 parts of deionized water.
4. The skin care and moisturizing essence of claim 1, wherein the moisturizer comprises 3 to 7 parts of glycerin, 2 to 5 parts of furcellaran-H, 3 to 5 parts of neopentyl glycol didecanoate, 1 to 3 parts of glycerol tri (ethyl hexanoate), 1 to 2 parts of damanthate, 1 to 5 parts of propylene glycol, and 0.1 to 0.5 part of Bridgkin's fruit oil.
5. The high-stability skin-care moisturizing particle essence of claim 4, wherein the thickener comprises 0.1-0.3 parts of xanthan gum, 0.1-0.3 parts of carbomer and 1-3 parts of behenyl alcohol.
6. The skin care and moisturizing essence with high stability as claimed in claim 5, wherein the emollient comprises 0.5-2 parts of 1, 2-hexanediol, 0.05-0.2 parts of carnosine, 1-3 parts of liquid silicone, and 0.1-1 part of oryzanol.
7. The skin-care moisturizing essence with high stability of claim 6, wherein the antioxidant comprises 0.5-1 parts of p-hydroxyacetophenone, 0.1-0.5 parts of astaxanthin and 0.01-0.05 parts of ergothioneine.
8. The skin care and moisturizing essence of claim 7, wherein the pH regulator is triethanolamine.
9. The skin care and moisturizing essence of claim 8, wherein the skin conditioner comprises 1-3 parts of stearic acid and 1-3 parts of ethylhexyl hydroxystearate.
10. The preparation method of the skin-care moisturizing essence with high stability as claimed in any one of claims 1 to 9, which is characterized by comprising the following steps:
step one, well doing sanitary cleaning work, strictly cleaning and disinfecting equipment and utensils;
step two, adding the humectant and the thickener into deionized water at the temperature of 80-85 ℃, uniformly stirring, and cooling to 45 ℃;
step three, heating the emollient and the skin conditioner to 80 ℃, uniformly stirring, and cooling to 75 ℃;
step four, adding the humectant and the thickener which are uniformly mixed in the step two into the emollient and the skin conditioner in the step three, stirring at a medium speed until no oil phase exists on the surface, and controlling to stir at a slow speed;
step five, adding the antioxidant, and uniformly stirring at a slow speed;
and step six, adding a pH regulator, and regulating the pH to 5-5.5 to obtain a finished product.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114366696A (en) * | 2022-01-07 | 2022-04-19 | 广州妮趣化妆品有限公司 | A nanometer emulsion of fructus Bruceae oil with antiaging effect, and its preparation method and application |
CN114469804A (en) * | 2022-01-26 | 2022-05-13 | 南昌大学第一附属医院 | Method for preparing skin cream |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107875037A (en) * | 2017-11-08 | 2018-04-06 | 诺斯贝尔化妆品股份有限公司 | A kind of skin softening gel containing color wax and preparation method thereof |
CN107951753A (en) * | 2017-12-27 | 2018-04-24 | 广州善草纪化妆品有限公司 | A kind of composite skin care product, skin care item and its preparation method and application |
CN109846748A (en) * | 2018-11-02 | 2019-06-07 | 上海珈凯生物科技有限公司 | A kind of moisturiser containing black phycocolloid and preparation method thereof, application |
CN110742842A (en) * | 2019-11-12 | 2020-02-04 | 医美生物科技(上海)有限公司 | Essence composition for delaying skin aging and preparation method thereof |
CN112603870A (en) * | 2021-01-28 | 2021-04-06 | 广州希施尔化妆品有限公司 | Multi-effect essence cream and preparation method thereof |
CN113081890A (en) * | 2021-04-27 | 2021-07-09 | 上海肤徕生物高科技有限公司 | Essence with anti-sugar and anti-oxidation functions and preparation method thereof |
-
2021
- 2021-10-18 CN CN202111208637.6A patent/CN113876638A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107875037A (en) * | 2017-11-08 | 2018-04-06 | 诺斯贝尔化妆品股份有限公司 | A kind of skin softening gel containing color wax and preparation method thereof |
CN107951753A (en) * | 2017-12-27 | 2018-04-24 | 广州善草纪化妆品有限公司 | A kind of composite skin care product, skin care item and its preparation method and application |
CN109846748A (en) * | 2018-11-02 | 2019-06-07 | 上海珈凯生物科技有限公司 | A kind of moisturiser containing black phycocolloid and preparation method thereof, application |
CN110742842A (en) * | 2019-11-12 | 2020-02-04 | 医美生物科技(上海)有限公司 | Essence composition for delaying skin aging and preparation method thereof |
CN112603870A (en) * | 2021-01-28 | 2021-04-06 | 广州希施尔化妆品有限公司 | Multi-effect essence cream and preparation method thereof |
CN113081890A (en) * | 2021-04-27 | 2021-07-09 | 上海肤徕生物高科技有限公司 | Essence with anti-sugar and anti-oxidation functions and preparation method thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114366696A (en) * | 2022-01-07 | 2022-04-19 | 广州妮趣化妆品有限公司 | A nanometer emulsion of fructus Bruceae oil with antiaging effect, and its preparation method and application |
CN114469804A (en) * | 2022-01-26 | 2022-05-13 | 南昌大学第一附属医院 | Method for preparing skin cream |
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