CN113813355A - 一种用于肝硬化的药丸及其制备方法 - Google Patents
一种用于肝硬化的药丸及其制备方法 Download PDFInfo
- Publication number
- CN113813355A CN113813355A CN202111264428.3A CN202111264428A CN113813355A CN 113813355 A CN113813355 A CN 113813355A CN 202111264428 A CN202111264428 A CN 202111264428A CN 113813355 A CN113813355 A CN 113813355A
- Authority
- CN
- China
- Prior art keywords
- parts
- rhizoma
- radix
- pill
- raw materials
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种用于肝硬化的药丸,所述药丸由以下原料组成:柴胡、茵陈、丹参、莪术、白术、黄芪、淫羊藿、鳖甲、五味子、大腹皮、猪苓、茯苓、泽泻、白茅根、赤芍、三棱、延胡索、郁金、人参、熟地黄、当归、红花、金钱草、蛇舌草、虎杖和垂盆草;一种用于肝硬化的药丸的制备方法,包括以下步骤:称取制备药丸的原材料;将称取的所述原材料在60℃下进行杀;其后在60℃下烘干5h;进行磨粉,得到粒径为20μm的药粉;其后向所述药粉中掺入重量为所述药粉重量的20%的水在制丸机中进行制丸;其后在60℃下干燥6h;本发明制备的所述药丸集治疗肝硬化和保护肝功能于一体,能有效提高治疗肝硬化的有效率和治愈率。
Description
技术领域
本发明涉及中草药领域,具体是一种用于肝硬化的药丸的制备方法。
背景技术
肝硬化是临床常见的慢性进行性肝病,由一种或多种病因长期或反复作用形成的弥漫性肝损害。在我国大多数为肝炎后肝硬化,少部分为酒精性肝硬化和血吸虫性肝硬化。病理组织学上有广泛的肝细胞坏死、残存肝细胞结节性再生、结缔组织增生与纤维隔形成,导致肝小叶结构破坏和假小叶形成,肝脏逐渐变形、变硬而发展为肝硬化。早期由于肝脏代偿功能较强可无明显症状,后期则以肝功能损害和门脉高压为主要表现,并有多系统受累,晚期常出现上消化道出血、肝性脑病、继发感染、脾功能亢进、腹水、癌变等并发症。
所以治疗肝硬化的变得尤为重要,治疗肝硬化的药物的有效率和治愈率也变得举足轻重,在现有的治疗肝硬化或同类疾病药物中,在治疗过程中的有效率和治愈率都无法进一步提高。
发明内容
本发明的目的在于克服现有技术的不足,提供一种用于肝硬化的药丸的制备方法,以至少达到提高用于肝硬化药物的有效率和治愈率的目的。
本发明的目的是通过以下技术方案来实现的:一种用于肝硬化的药丸,所述药丸由以下原料组成:柴胡、茵陈、丹参、莪术、白术、黄芪、淫羊藿、鳖甲、五味子、大腹皮、猪苓、茯苓、泽泻、白茅根、赤芍、三棱、延胡索、郁金、人参、熟地黄、当归、红花、金钱草、蛇舌草、虎杖和垂盆草。
进一步的,所述药丸由以下原料组成:10份柴胡、90份茵陈、90份丹参、57份莪术、90份白术、90份黄芪、90份淫羊藿、135份鳖甲、67份五味子、90份大腹皮、90份猪苓、90份茯苓、90份泽泻、90份白茅根、90份赤芍、45份三棱、67份延胡索、90份郁金、67份人参、90份熟地黄、67份当归、27份红花、67份金钱草、90份蛇舌草、135份虎杖和135份垂盆草。
本发明涉及的所述药丸主要针对肝硬化中期和早期的患者进行治疗,通常能在一年内治愈。“肝属木、脾属土、肾属水,有土有水树木才能生长”,说明补肾、健脾对肝硬化的康复有重要的促进作用。本发明通过柴胡(北柴胡)和郁金舒肝理气;通过当归、丹参、三棱、莪术、赤芍、延胡索和红花活血化瘀;通过三棱、莪术和鳖甲软坚散结;通过大腹皮、猪苓、茯苓、泽泻和白茅根利水消胀,同时与健脾药(人参、黄芪、白术、茯苓)相配起到健脾利水的作用,与舒肝理气的药物(柴胡、郁金)相配起到行气利水的作用;通过人参、黄芪、白术、茯苓健脾;通过熟地黄、淫羊藿相配,使得肾阴肾阳双补;通过茵陈、金钱草、和虎杖清热利湿,与舒肝理气药(柴胡、郁金)相配具有舒肝利胆额功效;通过蛇舌草和虎杖清热、利湿、解毒;通过黄芪、五味子(北五味)、垂盆草和金钱草保护肝功能,降低转氨酶。
进一步的,所述药丸的制备方法具体包括以下步骤:
S1、称取制备药丸的原材料:称取10份柴胡、90份茵陈、90份丹参、57份莪术、90份白术、90份黄芪、90份淫羊藿、135份鳖甲、67份五味子、90份大腹皮、90份猪苓、90份茯苓、90份泽泻、90份白茅根、90份赤芍、45份三棱、67份延胡索、90份郁金、67份人参、90份熟地黄、67份当归、27份红花、67份金钱草、90份蛇舌草、135份虎杖和135份垂盆草备用;
S2、杀菌:将步骤S1称取的所述原材料放入微波炉中杀菌,杀菌温度设定为60℃;
S3、烘干:将步骤S2杀菌后的所述原材料放入烘干机中烘干,烘干温度设置为60℃,烘干时间设定为5h;
S4、磨粉、将步骤S3中烘干后的所述原材料进行磨粉,得到粒径为20μm的药粉;
S5、制丸、步骤S4得到的药粉放入制丸机中,并向所述药粉中掺水,经所述制丸机制备得到药丸;所述药粉的水的重量比为5:1;
S6、药丸干燥:将制备好的药丸置于烘干机中进行干燥,干燥温度设定为60℃,干燥时间为6h。
本发明的有益效果是:所以本发明涉及的药丸的功效相互协调,共同作用下促使肝硬化患者康复,提高药丸的有效率和治愈率,同时使治疗和养护集结于一体。
(1)本发明涉及的药丸通过舒肝理气和活血化淤两方面对肝硬化的进行治疗,可促进肝脏内的血液循环,即可增强肝细胞的供血供氧,肝脏血液循环增加可增加门静脉的血液流入肝脏,减轻门静脉、肠系膜静脉和食管及胃底静脉的压力。舒肝理气和活血化淤又可促进侧支循环的建立,也可减轻门静脉、肠系膜静脉和食管及胃底静脉的压力。
(2)同时本发明涉及的药丸还可软坚散结,即可以使硬化的肝脏变软,更进一步促进肝脏的血液循环。同时能利水消肿,使腹水渐渐消失,没有腹水的情况则可预防腹水的产生。
(3)本发明涉及的药丸还可健脾补肾和降低转氨酶、保护肝功能,可以营养肝细胞,恢复肝功能。同时舒肝利胆,可使胆管畅通,肝功能得以正常运行。清热利湿,可以改善肝脏内环竟,使肝脏的功能活动顺利进行。
(4)本发明涉及的药丸对肝硬化的有效率为100%,治愈率为50%。
具体实施方式
下面进一步详细描述本发明的技术方案,但本发明的保护范围不局限于以下所述。
实施例
一种用于肝硬化的药丸的制备方法,包括以下步骤:
S1、称取制备药丸的原材料:称取10g柴胡、90g茵陈、90g丹参、57g莪术、90g白术、90g黄芪、90g淫羊藿、135g鳖甲、67g五味子、90g大腹皮、90g猪苓、90g茯苓、90g泽泻、90g白茅根、90g赤芍、45g三棱、67g延胡索、90g郁金、67g人参、90g熟地黄、67g当归、27g红花、67g金钱草、90g蛇舌草、135g虎杖和135g垂盆草备用;
S2、杀菌:将步骤S1称取的所述原材料放入微波炉中杀菌,杀菌温度设定为60℃;
S3、烘干:将步骤S2杀菌后的所述原材料放入烘干机中烘干,烘干温度设置为60℃,烘干时间设定为5h;
S4、磨粉、将步骤S3中烘干后的所述原材料进行磨粉,得到粒径为20μm的药粉;
S5、制丸、步骤S4得到的药粉放入制丸机中,并向所述药粉中掺水,经所述制丸机制备得到药丸;所述药粉的水的重量比为5:1;
S6、药丸干燥:将制备好的药丸置于烘干机中进行干燥,干燥温度设定为60℃,干燥时间为6h;
S7、装袋:将干燥后的药丸每10g装一袋。
治疗方法:一日两次,早饭和晚饭前服,每次10克(1袋),三个月为一个疗程;感冒、发烧和月经期暂停服用。
治疗效果:本发明涉及的药丸对肝硬化的有效率为100%,治愈率为50%。
典型病例:
病例(一):魏绍双,男,60岁。于医院检查已患肝硬化早期,经别人介绍来我诊所就诊。用本发明制备的药丸进行治疗,舒肝理气、活血化淤、软坚散结、健脾补肾。毎日两次,每次十克,三个月为一疗程。病人服药半年(两个疗程)后,于2014年12月底到医院检查,结果肝硬化全愈。
病例(二):刘成林,男, 64岁,于2019年12月26日经子女介绍来我诊所就诊。医院B超显示肝硬化。就诊时面色偏黑,面部静脉显示明显。用本发明制备的药丸进行治疗,以舒肝理气、活血化淤、软坚散结、健脾补肾。服用4个疗程(十二个月)后,于2021年补到医院检查,肝功能和B超显示完全正常
病例(三):王德文,男, 53岁。经绵阳四0四医院检查为肝硬化,肝脏硬度35.2。患者面色发黄、发黑,肝区不适。用本发明制备的药丸进行治疗,以舒肝理气、活血化淤、软坚散结、健脾补肾。服用所述药丸7个疗程后,于2021年8月3日到绵阳四0四医院检查,检查结果显示肝脏硬度好转到8.7,肝功能正常,AG比值为2.2,各项指标基本正常。
病例(四):杨光维,男, 74岁。因为在医院B超和CT诊断为肝硬化,于2021年8月6日经别人介绍来我诊所就诊。就诊时患者头晕、有黑便,面色偏暗。用本发明制备的药丸进行治疗,于2021年8月15日开始服用该丸,一个疗程(三个月)后,于2021年9月22在医体检时,经彩超和CT检查结果,服用1个月零7天的所述药丸后,肝硬化有明显好转,再未出现便血的症状。现在仍在持续治疗中。
病例(五):鲁元平,男, 49岁,于2021年5月18日经蒋医生介绍来我诊所就诊。就诊时身目发黄严重,重度腹水,精神萎靡。总胆红素204.6,直接胆红素140.4,间接胆红素64.2。用本发明制备的药丸进行治疗,一疗程(三个月)吃完后,于2021年9月16复诊。身目发黄症状减轻百分之八十以上,精神大为好转。总胆红素减至155.6,直接胆红素减至118.8,间接胆红素减至36.6。服一个疗程后各项身体指标有明显好转,现还在持续治疗中。
病例(六):颊天模,男,82岁。因患肝硬化于2019年8月17日来我诊所就诊,就诊时患者面色暗黑,精神不好,腹水严重,肝区不舒服。用本发明制备的药丸(一个疗程)进行治疗。今日(2021年9月25日)打电话回访,患者家属回答说:当年一个疗程吃完后,病情有明显好转,各种症状都有改善。但患者岁数已大,不想服药,中西药都不吃,因停药一年多病情加重住进了医院。本案患者服用所述药丸一个疗程后症状有明显好转,也说明了该药丸的有效性。
Claims (3)
1.一种用于肝硬化的药丸,其特征在于,所述药丸由以下原料组成:柴胡、茵陈、丹参、莪术、白术、黄芪、淫羊藿、鳖甲、五味子、大腹皮、猪苓、茯苓、泽泻、白茅根、赤芍、三棱、延胡索、郁金、人参、熟地黄、当归、红花、金钱草、蛇舌草、虎杖和垂盆草。
2.根据权利要求1所述的一种用于肝硬化的药丸,其特征在于,所述药丸由以下原料组成:10份柴胡、90份茵陈、90份丹参、57份莪术、90份白术、90份黄芪、90份淫羊藿、135份鳖甲、67份五味子、90份大腹皮、90份猪苓、90份茯苓、90份泽泻、90份白茅根、90份赤芍、45份三棱、67份延胡索、90份郁金、67份人参、90份熟地黄、67份当归、27份红花、67份金钱草、90份蛇舌草、135份虎杖和135份垂盆草。
3.根据权利要求1所述的一种用于肝硬化的药丸的制备方法,其特征在于,包括以下步骤:
S1、称取制备药丸的原材料:称取10份柴胡、90份茵陈、90份丹参、57份莪术、90份白术、90份黄芪、90份淫羊藿、135份鳖甲、67份五味子、90份大腹皮、90份猪苓、90份茯苓、90份泽泻、90份白茅根、90份赤芍、45份三棱、67份延胡索、90份郁金、67份人参、90份熟地黄、67份当归、27份红花、67份金钱草、90份蛇舌草、135份虎杖和135份垂盆草备用;
S2、杀菌:将步骤S1称取的所述原材料放入微波炉中杀菌,杀菌温度设定为60℃;
S3、烘干:将步骤S2杀菌后的所述原材料放入烘干机中烘干,烘干温度设置为60℃,烘干时间设定为5h;
S4、磨粉、将步骤S3中烘干后的所述原材料进行磨粉,得到粒径为20μm的药粉;
S5、制丸、步骤S4得到的药粉放入制丸机中,并向所述药粉中掺水,经所述制丸机制备得到药丸;所述药粉的水的重量比为5:1;
S6、药丸干燥:将制备好的药丸置于烘干机中进行干燥,干燥温度设定为60℃,干燥时间为6h。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111264428.3A CN113813355A (zh) | 2021-10-28 | 2021-10-28 | 一种用于肝硬化的药丸及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111264428.3A CN113813355A (zh) | 2021-10-28 | 2021-10-28 | 一种用于肝硬化的药丸及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113813355A true CN113813355A (zh) | 2021-12-21 |
Family
ID=78919086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111264428.3A Pending CN113813355A (zh) | 2021-10-28 | 2021-10-28 | 一种用于肝硬化的药丸及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN113813355A (zh) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102861310A (zh) * | 2012-09-17 | 2013-01-09 | 喻可安 | 乙肝药 |
CN103908640A (zh) * | 2014-04-25 | 2014-07-09 | 解建峰 | 一种治疗肝硬化的中药组合物 |
CN104547774A (zh) * | 2015-01-14 | 2015-04-29 | 孙顺新 | 一种治疗肝病的中药组合物及其制备方法与用途 |
-
2021
- 2021-10-28 CN CN202111264428.3A patent/CN113813355A/zh active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102861310A (zh) * | 2012-09-17 | 2013-01-09 | 喻可安 | 乙肝药 |
CN103908640A (zh) * | 2014-04-25 | 2014-07-09 | 解建峰 | 一种治疗肝硬化的中药组合物 |
CN104547774A (zh) * | 2015-01-14 | 2015-04-29 | 孙顺新 | 一种治疗肝病的中药组合物及其制备方法与用途 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102488850B (zh) | 治疗酒精性脂肪肝的中药组合物及其制备方法 | |
CN102319407B (zh) | 一种治疗胃下垂的中药及其提取方法 | |
ZA200302647B (en) | Novel medicinal herbal composition for treating liver diseases. | |
CN103908640A (zh) | 一种治疗肝硬化的中药组合物 | |
CN102657835B (zh) | 治疗高血压或/和类风湿性关节炎的组合物、药酒及其制备方法和应用 | |
CN102319408B (zh) | 一种健脾化湿治疗胃下垂的中药及其提取方法 | |
CN1692939A (zh) | 一种治疗乙型肝炎中药药丸的制作方法 | |
CN1245707A (zh) | 一种治疗艾滋病及癌症的药物 | |
CN101708297A (zh) | 一种治疗痛风病的药物 | |
CN101229355B (zh) | 风湿汤 | |
CN103301267B (zh) | 一种治疗高血压和/或动脉粥样硬化的中药组合物及应用 | |
CN103721185A (zh) | 一种治疗脾虚气陷证型胃下垂病的中药 | |
CN103599495A (zh) | 一种治疗乙肝的中药组合物 | |
CN108042766A (zh) | 一种补肾通络养脑膏及其制备方法 | |
CN104958448A (zh) | 一种治疗产褥感染的药物 | |
CN102327572B (zh) | 一种平补元气治疗胃下垂的中药 | |
CN100534506C (zh) | 一种治疗病毒性肝炎的中药组合物 | |
CN101244183B (zh) | 一种治疗小儿肠系膜淋巴结肿大的中药组合物 | |
CN104147526A (zh) | 一种治疗黄疸型肝炎的中药颗粒及其制备方法 | |
CN113813355A (zh) | 一种用于肝硬化的药丸及其制备方法 | |
CN103690869B (zh) | 治疗肠易激综合征的中药及其制备方法 | |
CN101549136A (zh) | 一种治疗类风湿性关节炎的药物 | |
CN103656199B (zh) | 一种治疗肾阴不足证型咳嗽的中药 | |
CN103212033B (zh) | 一种治疗病毒性肝炎的药物组合物 | |
CN102309725B (zh) | 治疗乙肝肝硬化中药制剂及制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211221 |
|
RJ01 | Rejection of invention patent application after publication |