CN113812666A - High-concentration CBD electronic atomized liquid with large smoke generation amount and preparation method thereof - Google Patents
High-concentration CBD electronic atomized liquid with large smoke generation amount and preparation method thereof Download PDFInfo
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Abstract
A high-concentration CBD electronic atomized liquid with large smoke quantity and a preparation method thereof belong to the technical field of electronic atomized liquid processing, and particularly relate to a CBD electronic atomized liquid and a preparation method thereof. The invention aims to solve the problem that the existing electronic atomized liquid containing CBD can not keep large smoke volume under the condition of high-concentration CBD. The electronic atomized liquid comprises propylene glycol, vegetable glycerin, cannabidiol crystal, 5 essence/cooling agent mixture and nicotine salt. The preparation method comprises the following steps: firstly, weighing; and secondly, mixing to obtain the high-concentration CBD electronic atomized liquid with large smoke amount. The advantages are that: the characters are clear and stable; the CBD content reaches 5-20%, and the smoke amount is closer to the mouth feel of the traditional cigarette; can better assist smokers to quit smoking and reduce the irritation to the lung and the generation of macromolecular smoke particles. The invention is mainly used for preparing the CBD electronic atomized liquid.
Description
Technical Field
The invention belongs to the technical field of electronic atomized liquid processing, and particularly relates to CBD electronic atomized liquid and a preparation method thereof.
Background
Tar and carbon monoxide in cigarettes are important factors harmful to human health, so smoking cessation is an action that every smoker should take; however, smoking is addictive, so that smoking cessation is difficult to smoothly carry out, the electronic cigarette does not contain tar and carbon monoxide, and is a healthier smoking mode, on one hand, the electronic cigarette can meet the smoking requirements of smokers, and on the other hand, the situation that the tar and the carbon monoxide in the cigarette are harmful to the health of people can be avoided.
Cannabidiol (CBD) is white crystal powder extracted from industrial cannabis sativa, can reduce addiction, weaken nerve stimulation, relieve relaxation and have no addiction, and based on the advantages, the CBD can be added into the electronic cigarette to effectively reduce smoking addiction and smoking frequency so as to achieve the aim of smoking cessation, but important components of vegetable glycerol and propylene glycol which smoke in the existing electronic cigarette have the melting point of more than 65 ℃, are solid at low temperature and are oil-soluble substances; the propylene glycol and the vegetable glycerin are not easy to disperse to form emulsion at low temperature (45 ℃); and the liquid cannabidiol can be preferentially wrapped by the vegetable glycerol and cooled to form hard white solid particles to be suspended in the solution, and the hard white solid particles can not be continuously decomposed when being heated, so that the vegetable glycerol and the cannabidiol are easy to form white solidified hard blocks, the service life of the electronic cigarette is reduced, and the smoking experience of smokers can be influenced. In order to solve the problem, the existing method for reducing the glycerin content of the vegetables or the CBD content is adopted, but the glycerin content of the vegetables is low, so that the smoke quantity is insufficient, and people cannot feel the smoke satisfaction; the CBD content is low, and the content required by inhalation cannot be achieved; therefore, the existing CBD-containing electronic atomized liquid cannot realize the problem of keeping the smoke volume large under the condition of high concentration CBD.
Disclosure of Invention
The invention aims to solve the problem that the existing CBD-containing electronic atomized liquid can not keep large smoke emission under the condition of high-concentration CBD, and provides the high-concentration CBD electronic atomized liquid with large smoke emission and the preparation method thereof.
A high-concentration CBD electronic atomized liquid with large smoke quantity comprises, by weight, 30-40 parts of propylene glycol, 30-50 parts of vegetable glycerin, 5-20 parts of cannabidiol crystals, 5-10 parts of an essence/cooling agent mixture and 3-5 parts of nicotine salt; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2).
A preparation method of high-concentration CBD electronic atomized liquid with large smoke emission amount is specifically completed according to the following steps:
firstly, weighing: weighing 30-40 parts of propylene glycol, 30-50 parts of vegetable glycerol, 5-20 parts of cannabidiol crystals, 5-10 parts of essence/cooling agent mixture and 3-5 parts of nicotine salt according to parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2);
secondly, mixing: uniformly stirring and mixing the propylene glycol and the vegetable glycerol weighed in the step one by a high-speed shearing machine under the oil bath heating condition to obtain a propylene glycol/vegetable glycerol mixture, and uniformly dividing the propylene glycol/vegetable glycerol mixture into 2 parts; heating and dissolving the cannabidiol crystal weighed in the step one in a solvent oil bath, adding 1 part of the propylene glycol/vegetable glycerin mixture in the step two, stirring and mixing the mixture by a high-speed shearing machine under the oil bath heating condition until the solvent is completely evaporated, adding the 1 part of the propylene glycol/vegetable glycerin mixture in the step two, continuously stirring and uniformly mixing the mixture by the high-speed shearing machine under the oil bath heating condition, naturally cooling the mixture to room temperature, and then performing rotary oscillation to obtain a medium mixture; thirdly, stirring and mixing the medium mixture under the oil bath heating condition through a high-speed shearing machine until the medium mixture is clarified, then adding the essence/cooling agent mixture and the nicotine salt weighed in the step one, and continuously stirring the mixture under the oil bath heating condition through the high-speed shearing machine until the mixture is clarified to obtain the high-concentration CBD electronic atomized liquid with large smoke emission.
The invention has the advantages that:
firstly, the propylene glycol and the vegetable glycerol are uniformly stirred by a high-speed shearing machine under the oil bath heating condition, the propylene glycol/vegetable glycerol mixture is added into the cannabidiol solution by times by the high-speed shearing machine under the oil bath heating condition (cannabidiol crystals are dissolved by using a solvent), the mixture is cooled to room temperature and then is swirled, the mixture is stirred by the high-speed shearing machine under the oil bath heating condition again until the mixture is clarified, the essence/cooling agent mixture and the nicotine salt are added, and then the mixture is stirred by the high-speed shearing machine under the oil bath heating condition until the mixture is clarified, so that the high-concentration CBD electronic atomized liquid with large smoke emission is obtained, and therefore, the problem that the high-content CBD is blocked in the vegetable glycerol cannot be used is solved by a physical mode.
Secondly, the CBD content in the high-concentration CBD electronic atomized liquid with large smoke quantity reaches 5-20%, the vegetable glycerin content is 30-50%, the CBD content is high, the smoke quantity is closer to the mouth feel of the traditional cigarette, and no fake smoke feeling is brought to people.
The high-concentration CBD electronic atomized liquid with large smoke quantity has high CBD content, can reduce mental addiction, has no addiction, and can better assist smokers to quit smoking.
Compared with the electronic atomized liquid of the existing electronic cigarette, the high-concentration CBD electronic atomized liquid with large smoke quantity has the advantage that the content of propylene glycol is reduced, so that the irritation to the lung and the generation of macromolecular smoke particles can be reduced.
Fifth, the electronic cigarette without nicotine belongs to mandatory nicotine withdrawal, which can cause the spirit or body discomfort of smokers and death of serious smokers, and the high-concentration CBD electronic atomized liquid with large smoke generation amount of the invention is added with a small amount of nicotine salt (the content is 3-5 percent), which can avoid the above problems.
Drawings
FIG. 1 is a chromatogram of a high-concentration CBD electronic atomized liquid with a large smoke emission obtained in example 1;
FIG. 2 is a photograph of an electron-atomized liquid, in which A represents the CBD electron-atomized liquid obtained in comparative example 1, and B represents the high-concentration CBD electron-atomized liquid with a large amount of smoke obtained in example 1.
Detailed Description
The first embodiment is as follows: the embodiment is a high-concentration CBD electronic atomized liquid with large smoke quantity, which comprises 30-40 parts of propylene glycol, 30-50 parts of vegetable glycerin, 5-20 parts of cannabidiol crystals, 5-10 parts of essence/cooling agent mixture and 3-5 parts of nicotine salt in parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2).
The propylene glycol of the present embodiment is produced by the dow group of america.
The vegetable glycerin according to the present embodiment is produced by malabao corporation.
The cannabidiol crystal according to the present embodiment is produced by Harbin Hanbo Biotech Co., Ltd.
The second embodiment is as follows: the present embodiment differs from the first embodiment in that: the high-concentration CBD electronic atomized liquid with large smoke quantity comprises, by weight, 40 parts of propylene glycol, 30 parts of vegetable glycerin, 20 parts of cannabidiol crystals, 7 parts of an essence/cooling agent mixture and 3 parts of nicotine salt. The rest is the same as the first embodiment.
The third concrete implementation mode: the present embodiment differs from the first or second embodiment in that: the high-concentration CBD electronic atomized liquid with large smoke quantity comprises, by weight, 35 parts of propylene glycol, 45 parts of vegetable glycerin, 10 parts of cannabidiol crystals, 5 parts of an essence/cooling agent mixture and 5 parts of nicotine salt. The others are the same as in the first or second embodiment.
The fourth concrete implementation mode: the difference between this embodiment and one of the first to third embodiments is as follows: the high-concentration CBD electronic atomized liquid with large smoke quantity comprises, by weight, 30 parts of propylene glycol, 50 parts of vegetable glycerin, 5 parts of cannabidiol crystals, 10 parts of an essence/cooling agent mixture and 5 parts of nicotine salt. The others are the same as the first to third embodiments.
The fifth concrete implementation mode: the difference between this embodiment and one of the first to fourth embodiments is: the edible essence is one or more of mint essence, fruit essence and fresh flower essence; the cooling agent is cooling agent WS-23. The rest is the same as the first to fourth embodiments.
The mint essence, the fruit essence or the fresh flower essence according to the embodiment is produced by Huabao group, Ltd.
The cooling agent WS-23 of the embodiment is produced by Huabao group Limited.
The sixth specific implementation mode: the difference between this embodiment and one of the first to fifth embodiments is as follows: the purity of CBD in the cannabidiol crystal is more than 99%. The rest is the same as the first to fifth embodiments.
The seventh embodiment: the embodiment is a preparation method of high-concentration CBD electronic atomized liquid with large smoke quantity, which is specifically completed according to the following steps:
firstly, weighing: weighing 30-40 parts of propylene glycol, 30-50 parts of vegetable glycerol, 5-20 parts of cannabidiol crystals, 5-10 parts of essence/cooling agent mixture and 3-5 parts of nicotine salt according to parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2);
secondly, mixing: uniformly stirring and mixing the propylene glycol and the vegetable glycerol weighed in the step one by a high-speed shearing machine under the oil bath heating condition to obtain a propylene glycol/vegetable glycerol mixture, and uniformly dividing the propylene glycol/vegetable glycerol mixture into 2 parts; heating and dissolving the cannabidiol crystal weighed in the step one in a solvent oil bath, adding 1 part of the propylene glycol/vegetable glycerin mixture in the step two, stirring and mixing the mixture by a high-speed shearing machine under the oil bath heating condition until the solvent is completely evaporated, adding the 1 part of the propylene glycol/vegetable glycerin mixture in the step two, continuously stirring and uniformly mixing the mixture by the high-speed shearing machine under the oil bath heating condition, naturally cooling the mixture to room temperature, and then performing rotary oscillation to obtain a medium mixture; thirdly, stirring and mixing the medium mixture under the oil bath heating condition through a high-speed shearing machine until the medium mixture is clarified, then adding the essence/cooling agent mixture and the nicotine salt weighed in the step one, and continuously stirring the mixture under the oil bath heating condition through the high-speed shearing machine until the mixture is clarified to obtain the high-concentration CBD electronic atomized liquid with large smoke emission.
The specific implementation mode is eight: the seventh embodiment is different from the seventh embodiment in that: in the first step, 40 parts of propylene glycol, 30 parts of vegetable glycerin, 20 parts of cannabidiol crystals, 7 parts of essence/cooling agent mixture and 3 parts of nicotine salt are weighed according to parts by weight. The rest is the same as the seventh embodiment.
The specific implementation method nine: the seventh embodiment is different from the seventh embodiment in that: in the first step, 35 parts of propylene glycol, 45 parts of vegetable glycerin, 10 parts of cannabidiol crystals, 5 parts of an essence/cooling agent mixture and 5 parts of nicotine salt are weighed according to parts by weight. The rest is the same as the seventh embodiment.
The detailed implementation mode is ten: the seventh embodiment is different from the seventh embodiment in that: in the first step, 30 parts of propylene glycol, 50 parts of vegetable glycerin, 5 parts of cannabidiol crystals, 10 parts of essence/cooling agent mixture and 5 parts of nicotine salt are weighed according to parts by weight. The rest is the same as the seventh embodiment.
The concrete implementation mode eleven: the seventh to tenth embodiments are different from the first to seventh embodiments in that: in the step one, the edible essence is one or more of mint essence, fruit essence and fresh flower essence; the cooling agent is cooling agent WS-23. The rest is the same as the seventh to tenth embodiments.
The mint essence, the fruit essence or the fresh flower essence according to the embodiment is produced by Huabao group, Ltd.
The cooling agent WS-23 of the embodiment is produced by Huabao group Limited.
The specific implementation mode twelve: the seventh to eleventh embodiments are different from the first to the second embodiments in that: in the step one, the purity of CBD in the cannabidiol crystal is more than 99%. The others are the same as in embodiments seven to eleven.
The specific implementation mode is thirteen: the seventh to twelfth embodiments are different from the seventh to twelfth embodiments in that: mixing the propylene glycol and the vegetable glycerol weighed in the step one, heating in an oil bath to 75-85 ℃, stirring and mixing at the rotation speed of 13000 r/min-15000 r/min for 2 min-3 min at the temperature of 75-85 ℃ through a high-speed shearing machine, continuing heating to 115-125 ℃, continuing heating at the temperature of 115-125 ℃ for 25 min-35 min to obtain a propylene glycol/vegetable glycerol mixture, and uniformly dividing the propylene glycol/vegetable glycerol mixture into 2 parts. The rest is the same as the seventh to twelfth embodiments.
The specific implementation mode is fourteen: the seventh to twelfth points of this embodiment are different from the seventh to twelfth points of the embodiment: step two, adding the cannabidiol crystals weighed in the step one into a solvent, heating the mixture to 65-75 ℃ in an oil bath, heating the mixture at the temperature of 65-75 ℃, stirring the mixture until the cannabidiol crystals are completely dissolved, then adding 1 part of the propylene glycol/vegetable glycerin mixture in the second step, stirring and mixing at the high-speed shearing machine at the rotating speed of 16000 r/min-20000 r/min at the temperature of 115-125 ℃ until the solvent is completely evaporated, adding 1 part of the propylene glycol/vegetable glycerin mixture in the second step, continuously stirring and mixing the mixture for 5 to 10 minutes at the temperature of 115 to 125 ℃ by a high-speed shearing machine at the rotating speed of 15000 to 17000r/min, naturally cooling the mixture to room temperature, and performing rotary oscillation for 20 to 30 hours at the temperature of 25 ℃ by a constant-temperature oscillator at the rotating speed of 100 to 150r/min to obtain a medium mixture; the solvent is absolute ethyl alcohol. The others are the same as those of the seventh to thirteenth embodiments.
The concrete implementation mode is fifteen: the seventh to fourteenth embodiments are different from the first to the second embodiments in that: and step two, heating the intermediate mixture in a water bath to 85-95 ℃, stirring and mixing the intermediate mixture at 85-95 ℃ through a high-speed shearing machine at the rotating speed of 10000 r/min-12000 r/min until the intermediate mixture is clarified, then adding the essence/cooling agent mixture and the nicotine salt weighed in the step one, stirring and mixing the mixture at the temperature of 85-95 ℃ through the high-speed shearing machine at the rotating speed of 8000 r/min-12000 r/min until the intermediate mixture is clarified, and obtaining the high-concentration CBD electronic atomized liquid with large smoke emission. The rest is the same as the seventh to the fourteenth embodiments.
The invention is not limited to the above embodiments, and one or a combination of several embodiments may also achieve the object of the invention.
The following tests are adopted to verify the effect of the invention:
example 1: a preparation method of high-concentration CBD electronic atomized liquid with large smoke emission amount is specifically completed according to the following steps:
firstly, weighing: weighing 40 parts of propylene glycol, 30 parts of vegetable glycerol, 20 parts of cannabidiol crystals, 7 parts of essence/cooling agent mixture and 3 parts of nicotine salt according to parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2: 1;
secondly, mixing: mixing the propylene glycol and the vegetable glycerol weighed in the step one, heating the mixture in an oil bath to 80 ℃, stirring and mixing the mixture for 3min at the rotation speed of 14000r/min by a high-speed shearing machine at the temperature of 80 ℃, continuously heating the mixture to 120 ℃, continuously heating the mixture for 30min at the temperature of 120 ℃ to obtain a propylene glycol/vegetable glycerol mixture, and uniformly dividing the propylene glycol/vegetable glycerol mixture into 2 parts; adding the cannabidiol crystals weighed in the first step into a solvent, heating the mixture in an oil bath to 70 ℃, heating and stirring the mixture at the temperature of 70 ℃ until the cannabidiol crystals are completely dissolved, adding 1 part of the propylene glycol/vegetable glycerin mixture in the second step, stirring and mixing the mixture at the temperature of 120 ℃ through a high-speed shearing machine at the rotating speed of 18000r/min until the solvent is completely evaporated, adding 1 part of the propylene glycol/vegetable glycerin mixture in the second step, stirring and mixing the mixture at the temperature of 120 ℃ through the high-speed shearing machine at the rotating speed of 16000r/min for 8min, naturally cooling the mixture to room temperature, and performing rotary oscillation on the mixture at the temperature of 25 ℃ at the rotating speed of 120r/min for 25h through a constant-temperature oscillation instrument to obtain a medium mixture; the solvent is absolute ethyl alcohol; thirdly, heating the mixture in water bath to 90 ℃, stirring and mixing the mixture at the temperature of 90 ℃ and the rotation speed of 11000r/min by a high-speed shearing machine until the mixture is clarified, then adding the essence/cooling agent mixture and the nicotine salt weighed in the first step, stirring and mixing the mixture at the temperature of 90 ℃ and the rotation speed of 10000r/min by the high-speed shearing machine until the mixture is clarified, and obtaining the high-concentration CBD electronic atomized liquid with large smoke emission.
In the first step of this embodiment, the edible essence is mint essence; the cooling agent is cooling agent WS-23.
In the first step of this embodiment, the purity of CBD in the cannabidiol crystals is 99% or more.
The mint, fruit or floral essence described in this example was produced by huabao group, inc.
The cooling agent WS-23 described in this example was produced by Huabao group, Inc.
The propylene glycol of the present embodiment is produced by the dow group of america.
The vegetable glycerin according to the present embodiment is produced by malabao corporation.
The cannabidiol crystal according to the present embodiment is produced by Harbin Hanbo Biotech Co., Ltd.
Liquid chromatography detection is performed on the high-concentration CBD electronic atomized liquid with large smoke generation amount obtained in example 1, as shown in fig. 1, fig. 1 is a chromatogram of the high-concentration CBD electronic atomized liquid with large smoke generation amount obtained in example 1, the retention time of cannabidiol is 5.347min, the corresponding factor is 35.529, the content is 18.34%, and the high-concentration CBD electronic atomized liquid with large smoke generation amount obtained in example 1 does not contain Tetrahydrocannabinol (THC).
Example 2: the present embodiment differs from embodiment 1 in that: in the first step, 35 parts of propylene glycol, 45 parts of vegetable glycerin, 10 parts of cannabidiol crystals, 5 parts of an essence/cooling agent mixture and 5 parts of nicotine salt are weighed according to parts by weight. The rest is the same as in example 1.
Example 3: the present embodiment differs from embodiment 1 in that: in the first step, 30 parts of propylene glycol, 50 parts of vegetable glycerin, 5 parts of cannabidiol crystals, 10 parts of essence/cooling agent mixture and 5 parts of nicotine salt are weighed according to parts by weight. The rest is the same as in example 1.
Comparative example 1: the prior method comprises the following steps:
weighing 40 parts of propylene glycol, 30 parts of vegetable glycerin, 20 parts of cannabidiol crystals, 7 parts of essence/cooling agent mixture and 3 parts of nicotine salt according to parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2: 1;
secondly, adding propylene glycol into vegetable glycerin at the temperature of 55 ℃, stirring for 20min, then adding a cooling agent and an essence/cooling agent mixture, and stirring for 10min to obtain a primary mixture: adding the cannabidiol crystals into the solvent, and stirring until the cannabidiol crystals are completely dissolved to obtain a cannabidiol solution; dropwise adding the cannabidiol solution into the primary mixture, after 10min of dropwise addition, blowing nitrogen gas with the flow rate of 10mL/min, continuously stirring for 60min, cooling to obtain a semi-finished product, standing for 3h, filtering by using a filter screen to remove impurities, wherein the aperture of the filter screen is 2000 meshes, and standing for 2h to obtain the CBD electronic atomized liquid.
In the first step of this embodiment, the edible essence is mint essence; the cooling agent is cooling agent WS-23.
In the first step of this embodiment, the purity of CBD in the cannabidiol crystals is 99% or more.
The mint, fruit or floral essence described in this example was produced by huabao group, inc.
The cooling agent WS-23 described in this example was produced by Huabao group, Inc.
The propylene glycol of the present embodiment is produced by the dow group of america.
The vegetable glycerin according to the present embodiment is produced by malabao corporation.
The cannabidiol crystal according to the present embodiment is produced by Harbin Hanbo Biotech Co., Ltd.
FIG. 2 is a photograph of an electron-atomized liquid, in which A represents the CBD electron-atomized liquid obtained in comparative example 1, and B represents the high-concentration CBD electron-atomized liquid with a large amount of smoke obtained in example 1; as can be seen from fig. 2, the high-concentration CBD electronic atomized liquid with a large smoke emission obtained in example 1 is yellowish purple in color, clear and transparent, and no white foam or massive solid is generated; because the glycerol contains three hydroxyl groups and is strong in hydrophilicity, the cannabidiol is a resorcinol compound, the side chain contains cyclohexene and ethylene structures, and is more oleophilic, and the two are mixed at normal temperature in a large amount to cause double bond damage, contraction and solidification, so that white foam appears in the CBD electronic atomized liquid obtained in the comparative example 1.
The electronic cigarette smoke amount test was carried out according to the method provided in the "method for evaluating the electronic cigarette smoke amount" (application No. CN201410380290.7) published in china on examples 1 to 3, comparative example 1, commercially available CBD-free tobacco tar, Vegetable Glycerin (VG), Propylene Glycol (PG), and a vegetable glycerin/propylene glycol mixture (vegetable glycerin/propylene glycol mixture is formed by mixing vegetable glycerin and propylene glycol in the sequence of vegetable glycerin to propylene glycol mass ratios of 8:2, 6:4, 5:5, 4:6, and 2:8), and the test results are shown in table 1.
TABLE 1
As can be seen from table 1, the smoke quality of Vegetable Glycerin (VG) alone is the highest, and the smoke quality gradually decreases as Propylene Glycol (PG) increases, so that the smoke generation amount can be increased by increasing Vegetable Glycerin (VG).
As can be seen from table 1, the smoke quality of the high-concentration CBD electronic atomized liquid with large smoke generation amount prepared by the present invention is significantly higher than that of the commercially available CBD-free tobacco tar in comparison with the commercially available CBD-free tobacco tar in examples 1 to 3; the high-concentration CBD electronic atomized liquid with large smoke generation amount obtained by the invention has the advantage of large smoke generation amount; compared with the comparative example 1, the smoke quality of the high-concentration CBD electronic atomized liquid with large smoke generation amount prepared in the example 1 is obviously higher than that of the CBD electronic atomized liquid obtained in the comparative example 1, so that the improvement of the preparation method provided by the invention can obviously improve the smoke generation amount.
Claims (10)
1. The high-concentration CBD electronic atomized liquid with large smoke quantity is characterized by comprising 30-40 parts by weight of propylene glycol, 30-50 parts by weight of vegetable glycerin, 5-20 parts by weight of cannabidiol crystals, 5-10 parts by weight of essence/cooling agent mixture and 3-5 parts by weight of nicotine salt; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2).
2. The CBD electronic atomized liquid with large smoke generation amount of claim 1, wherein the CBD electronic atomized liquid with large smoke generation amount comprises, by weight, 40 parts of propylene glycol, 30 parts of vegetable glycerin, 20 parts of cannabidiol crystals, 7 parts of essence/cooling agent mixture and 3 parts of nicotine salt.
3. The CBD electronic atomized liquid with large smoke generation amount of claim 1, wherein the CBD electronic atomized liquid with large smoke generation amount comprises 35 parts by weight of propylene glycol, 45 parts by weight of vegetable glycerin, 10 parts by weight of cannabidiol crystals, 5 parts by weight of flavor/cooling agent mixture and 5 parts by weight of nicotine salt.
4. The CBD electronic atomized liquid with large smoke generation amount of claim 1, wherein the CBD electronic atomized liquid with large smoke generation amount comprises 30 parts by weight of propylene glycol, 50 parts by weight of vegetable glycerin, 5 parts by weight of cannabidiol crystals, 10 parts by weight of flavor/cooling agent mixture and 5 parts by weight of nicotine salt.
5. The high-concentration CBD electronic atomized liquid with large smoke generation amount according to the claim 1, 2, 3 or 4, wherein the edible essence is one or more of mint essence, fruit essence and fresh flower essence; the cooling agent is cooling agent WS-23.
6. The highly concentrated CBD electrospray with high smoke generation according to claim 5, wherein the CBD purity in the cannabidiol crystals is above 99%.
7. A preparation method of high-concentration CBD electronic atomized liquid with large smoke quantity is characterized by comprising the following steps:
firstly, weighing: weighing 30-40 parts of propylene glycol, 30-50 parts of vegetable glycerol, 5-20 parts of cannabidiol crystals, 5-10 parts of essence/cooling agent mixture and 3-5 parts of nicotine salt according to parts by weight; the flavor/cooling agent mixture is formed by mixing edible flavor and cooling agent, and the mass ratio of the edible flavor to the cooling agent is 2 (0.8-1.2);
secondly, mixing: uniformly stirring and mixing the propylene glycol and the vegetable glycerol weighed in the step one by a high-speed shearing machine under the oil bath heating condition to obtain a propylene glycol/vegetable glycerol mixture, and uniformly dividing the propylene glycol/vegetable glycerol mixture into 2 parts; heating and dissolving the cannabidiol crystal weighed in the step one in a solvent oil bath, adding 1 part of the propylene glycol/vegetable glycerin mixture in the step two, stirring and mixing the mixture by a high-speed shearing machine under the oil bath heating condition until the solvent is completely evaporated, adding the 1 part of the propylene glycol/vegetable glycerin mixture in the step two, continuously stirring and uniformly mixing the mixture by the high-speed shearing machine under the oil bath heating condition, naturally cooling the mixture to room temperature, and then performing rotary oscillation to obtain a medium mixture; thirdly, stirring and mixing the medium mixture under the oil bath heating condition through a high-speed shearing machine until the medium mixture is clarified, then adding the essence/cooling agent mixture and the nicotine salt weighed in the step one, and continuously stirring the mixture under the oil bath heating condition through the high-speed shearing machine until the mixture is clarified to obtain the high-concentration CBD electronic atomized liquid with large smoke emission.
8. The preparation method of the high-concentration CBD electronic atomized liquid with large smoke emission according to claim 7, wherein the second step is that the propylene glycol weighed in the first step is mixed with vegetable glycerin, then the mixture is subjected to oil bath heating to 75-85 ℃, and is stirred and mixed for 2-3 min at the rotation speed of 13000-15000 r/min by a high-speed shearing machine at the temperature of 75-85 ℃, and is further heated to 115-125 ℃, and is further heated for 25-35 min at the temperature of 115-125 ℃ to obtain a propylene glycol/vegetable glycerin mixture, and the propylene glycol/vegetable glycerin mixture is divided into 2 parts.
9. The method for preparing high-concentration CBD electronic atomized liquid with large smoke emission according to claim 8, wherein the second step comprises adding the cannabidiol crystals weighed in the first step into a solvent, heating the mixture in an oil bath to 65-75 ℃, heating and stirring the mixture at 65-75 ℃ until the cannabidiol crystals are completely dissolved, adding 1 part of propylene glycol/vegetable glycerin mixture in the second step, stirring and mixing the mixture at a high speed of 16000 r/min-20000 r/min by a high speed shearing machine at a temperature of 115-125 ℃ until the solvent is completely evaporated, adding 1 part of propylene glycol/vegetable glycerin mixture in the second step, stirring and mixing the mixture at a high speed of 15000 r/min-17000 r/min by a high speed shearing machine at a temperature of 115-125 ℃ for 5-10 min, naturally cooling the mixture to room temperature, and shaking the mixture at a constant temperature of 25 ℃ at a speed of 100 r/min-150 r/min for 20h The mixture is obtained after 30 hours; the solvent is absolute ethyl alcohol.
10. The method for preparing a high-concentration CBD electronic atomized liquid with large smoke emission according to claim 9, wherein the second step is heating the mixture in water bath to 85-95 ℃, stirring and mixing the mixture at 85-95 ℃ and 10000-12000 r/min by a high-speed shearing machine until the mixture is clarified, adding the essence/cooling agent mixture and nicotine salt weighed in the first step, stirring and mixing the mixture at 85-95 ℃ and 8000-12000 r/min by the high-speed shearing machine until the mixture is clarified, and obtaining the high-concentration CBD electronic atomized liquid with large smoke emission.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2023135408A1 (en) * | 2022-01-14 | 2023-07-20 | Nicoventures Trading Limited | Aerosolisable material |
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- 2021-11-08 CN CN202111314599.2A patent/CN113812666A/en active Pending
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| 李长征: "《<中华人名共和国禁毒法>贯彻实施与毒品监督管理、犯罪侦查及易制毒化学品管理执法实用手册》", 29 February 2008, 中国公安科学出版社 * |
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| WO2023135408A1 (en) * | 2022-01-14 | 2023-07-20 | Nicoventures Trading Limited | Aerosolisable material |
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